Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS324G03f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 76 9e-14
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 76 9e-14
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 76 9e-14
AB300051-1|BAF64841.1| 1044|Homo sapiens MEGF11 protein. 76 9e-14
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 76 9e-14
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 71 2e-12
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 71 2e-12
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 71 2e-12
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 71 2e-12
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 71 2e-12
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 71 2e-12
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 71 3e-12
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 71 3e-12
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 71 3e-12
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 71 3e-12
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 3e-12
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 3e-12
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 3e-12
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 3e-12
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 71 3e-12
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 71 3e-12
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 71 3e-12
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 70 6e-12
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 70 6e-12
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 70 6e-12
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 69 8e-12
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 69 8e-12
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 69 8e-12
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 69 1e-11
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 68 2e-11
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 68 2e-11
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 68 2e-11
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 68 2e-11
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 68 2e-11
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 68 2e-11
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 68 2e-11
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 67 3e-11
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 67 3e-11
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 67 3e-11
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 67 3e-11
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 67 3e-11
BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein. 67 4e-11
AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro... 67 4e-11
AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant... 67 4e-11
AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein. 67 4e-11
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 66 7e-11
BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. 66 7e-11
U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein ... 64 2e-10
BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and di... 64 2e-10
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 64 3e-10
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 64 3e-10
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 64 3e-10
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 64 3e-10
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 64 3e-10
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 64 3e-10
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 64 3e-10
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 64 3e-10
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 64 4e-10
BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog (D... 63 7e-10
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 63 7e-10
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 63 7e-10
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 63 7e-10
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 63 7e-10
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 63 7e-10
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 63 7e-10
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 63 7e-10
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 62 9e-10
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 62 1e-09
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 62 1e-09
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 62 1e-09
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 62 1e-09
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 62 2e-09
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 62 2e-09
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 61 2e-09
AL050329-2|CAB99359.1| 399|Homo sapiens protein ( Human DNA seq... 61 2e-09
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 61 2e-09
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 61 2e-09
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 61 2e-09
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 61 2e-09
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 61 2e-09
AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. 61 3e-09
U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein ... 60 3e-09
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 60 3e-09
BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein. 60 3e-09
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 60 3e-09
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 60 3e-09
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 60 3e-09
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 60 3e-09
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 60 3e-09
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 60 5e-09
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 60 5e-09
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 60 5e-09
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 60 5e-09
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 60 5e-09
AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein. 60 5e-09
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 60 5e-09
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 60 5e-09
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 60 6e-09
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 59 8e-09
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 59 8e-09
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 59 8e-09
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 59 8e-09
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 59 8e-09
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 59 8e-09
AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein. 59 1e-08
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 59 1e-08
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 59 1e-08
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 58 2e-08
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 58 2e-08
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 58 2e-08
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 58 2e-08
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 58 2e-08
DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 57 4e-08
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 57 4e-08
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 57 4e-08
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 57 4e-08
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 57 4e-08
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 57 4e-08
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 57 4e-08
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 57 4e-08
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 56 6e-08
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 56 6e-08
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 56 6e-08
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 56 6e-08
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 56 6e-08
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 56 8e-08
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 56 8e-08
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 56 8e-08
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 56 8e-08
BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t... 56 1e-07
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 56 1e-07
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 56 1e-07
AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 56 1e-07
AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 56 1e-07
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 56 1e-07
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 56 1e-07
AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 56 1e-07
AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 56 1e-07
AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 56 1e-07
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 56 1e-07
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 56 1e-07
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 55 1e-07
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 55 1e-07
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 55 1e-07
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 55 2e-07
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ... 54 2e-07
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote... 54 2e-07
J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroit... 54 2e-07
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr... 54 2e-07
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 54 2e-07
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 54 2e-07
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 54 2e-07
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro... 54 2e-07
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 54 3e-07
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 54 3e-07
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 54 3e-07
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 54 3e-07
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 54 3e-07
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 54 3e-07
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 53 7e-07
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 53 7e-07
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 53 7e-07
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 53 7e-07
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 53 7e-07
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 53 7e-07
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 53 7e-07
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ... 52 9e-07
D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) pro... 52 9e-07
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 52 1e-06
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 52 1e-06
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 52 1e-06
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 52 1e-06
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 52 2e-06
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 52 2e-06
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 52 2e-06
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 52 2e-06
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 52 2e-06
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 52 2e-06
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 52 2e-06
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 52 2e-06
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 52 2e-06
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 52 2e-06
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 52 2e-06
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 52 2e-06
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 52 2e-06
AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein. 51 3e-06
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 50 4e-06
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 50 5e-06
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 50 5e-06
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 50 5e-06
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 50 5e-06
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 50 5e-06
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 50 5e-06
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 50 5e-06
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 50 5e-06
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 50 5e-06
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 50 5e-06
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 50 7e-06
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 50 7e-06
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 50 7e-06
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 49 9e-06
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 49 9e-06
BC031251-1|AAH31251.1| 375|Homo sapiens EGF-like, fibronectin t... 49 9e-06
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 49 9e-06
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 49 9e-06
AK092479-1|BAC03900.1| 463|Homo sapiens protein ( Homo sapiens ... 49 9e-06
AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens ... 49 9e-06
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 49 1e-05
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 49 1e-05
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 49 1e-05
BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein. 49 1e-05
BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein. 49 1e-05
AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein. 49 1e-05
AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein. 49 1e-05
AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein. 49 1e-05
AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein. 49 1e-05
AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein. 49 1e-05
AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens ... 48 2e-05
BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1... 48 2e-05
AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein. 48 2e-05
AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1... 48 2e-05
AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein. 48 2e-05
AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS... 48 2e-05
AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein p... 48 2e-05
AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain c... 47 3e-05
X73902-1|CAA52108.1| 1193|Homo sapiens nicein protein. 47 5e-05
U31201-1|AAC50457.1| 1193|Homo sapiens laminin gamma2 chain prot... 47 5e-05
U31200-1|AAC50456.1| 1111|Homo sapiens alternatively spliced lam... 47 5e-05
BC113378-1|AAI13379.1| 1111|Homo sapiens laminin, gamma 2 protein. 47 5e-05
BC112286-1|AAI12287.1| 1111|Homo sapiens laminin, gamma 2 protein. 47 5e-05
AL354953-2|CAH70980.1| 1193|Homo sapiens laminin, gamma 2 protein. 47 5e-05
BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein pr... 46 6e-05
BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein pr... 46 6e-05
AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing p... 46 6e-05
AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand f... 46 6e-05
AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens ... 46 6e-05
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 46 6e-05
Z15009-1|CAA78729.1| 1111|Homo sapiens Laminin protein. 46 8e-05
Z15008-1|CAA78728.1| 1193|Homo sapiens Laminin protein. 46 8e-05
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 46 8e-05
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 46 8e-05
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 46 8e-05
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 46 8e-05
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 46 8e-05
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 46 8e-05
AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 46 8e-05
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 46 8e-05
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 46 8e-05
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 46 8e-05
AB086825-1|BAC45250.1| 788|Homo sapiens receptor protein tyrosi... 46 8e-05
Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 46 1e-04
Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 46 1e-04
Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog... 46 1e-04
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 46 1e-04
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 46 1e-04
AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 46 1e-04
AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 46 1e-04
AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homol... 46 1e-04
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 46 1e-04
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 46 1e-04
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 46 1e-04
AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein. 46 1e-04
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 46 1e-04
AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein. 45 1e-04
AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein. 45 1e-04
M35672-1|AAA51981.1| 291|Homo sapiens F9 protein. 45 2e-04
M11309-1|AAA52023.1| 461|Homo sapiens F9 protein. 45 2e-04
K02402-1|AAB59620.1| 461|Homo sapiens factor IX protein. 45 2e-04
K02053-1|AAA56822.1| 461|Homo sapiens protein ( Human factor IX... 45 2e-04
J00137-1|AAA52763.1| 461|Homo sapiens F9 protein. 45 2e-04
J00136-1|AAA98726.1| 462|Homo sapiens factor IX protein. 45 2e-04
DQ431790-1|ABF68979.1| 37|Homo sapiens coagulation factor IX p... 45 2e-04
BC109215-1|AAI09216.1| 461|Homo sapiens F9 protein protein. 45 2e-04
BC109214-1|AAI09215.1| 461|Homo sapiens F9 protein protein. 45 2e-04
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 45 2e-04
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 45 2e-04
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 45 2e-04
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 45 2e-04
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 45 2e-04
AL033403-1|CAI42103.1| 461|Homo sapiens coagulation factor IX (... 45 2e-04
AF536327-1|AAM96188.1| 461|Homo sapiens coagulation factor IX (... 45 2e-04
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 44 2e-04
BC063620-1|AAH63620.1| 488|Homo sapiens AGRN protein protein. 44 2e-04
BC007649-1|AAH07649.1| 488|Homo sapiens AGRN protein protein. 44 2e-04
AL645608-14|CAI15576.1| 270|Homo sapiens agrin protein. 44 2e-04
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 44 2e-04
S78220-1|AAB21215.1| 599|Homo sapiens prostaglandin endoperoxid... 44 3e-04
S36271-1|AAB22217.1| 599|Homo sapiens prostaglandin G/H synthas... 44 3e-04
S36219-1|AAB22216.1| 562|Homo sapiens prostaglandin G/H synthas... 44 3e-04
M59979-1|AAA03630.1| 599|Homo sapiens prostaglandin endoperoxid... 44 3e-04
M31822-1|AAA36439.1| 599|Homo sapiens prostaglandin-endoperoxid... 44 3e-04
DQ180742-1|ABA60099.1| 630|Homo sapiens cyclooxygenase 1b3 prot... 44 3e-04
DQ180741-1|ABA60098.1| 630|Homo sapiens cyclooxygenase 1b2 prot... 44 3e-04
BC105690-1|AAI05691.1| 195|Homo sapiens Unknown (protein for MG... 44 3e-04
BC078143-1|AAH78143.1| 446|Homo sapiens secretory protein LOC34... 44 3e-04
BC029840-1|AAH29840.1| 599|Homo sapiens prostaglandin-endoperox... 44 3e-04
BC013770-1|AAH13770.1| 530|Homo sapiens netrin G2 protein. 44 3e-04
AY449688-1|AAR08907.1| 599|Homo sapiens prostaglandin-endoperox... 44 3e-04
AL359636-8|CAM45741.1| 599|Homo sapiens prostaglandin-endoperox... 44 3e-04
AL359636-7|CAM45740.1| 562|Homo sapiens prostaglandin-endoperox... 44 3e-04
AL353631-2|CAI16125.1| 530|Homo sapiens netrin G2 protein. 44 3e-04
AL353631-1|CAI16126.1| 522|Homo sapiens netrin G2 protein. 44 3e-04
AL162424-14|CAI14715.1| 599|Homo sapiens prostaglandin-endopero... 44 3e-04
AL162424-13|CAI14714.1| 562|Homo sapiens prostaglandin-endopero... 44 3e-04
AL159997-4|CAI40856.1| 530|Homo sapiens netrin G2 protein. 44 3e-04
AL159997-3|CAI40855.1| 522|Homo sapiens netrin G2 protein. 44 3e-04
AF440204-1|AAL33601.1| 599|Homo sapiens prostaglandin-endoperox... 44 3e-04
AF131842-1|AAD20057.1| 260|Homo sapiens Unknown protein. 44 3e-04
AC007748-1|AAY24263.1| 162|Homo sapiens unknown protein. 44 3e-04
AB058760-1|BAB47486.2| 549|Homo sapiens KIAA1857 protein protein. 44 3e-04
BC141808-1|AAI41809.1| 446|Homo sapiens MGC34761 protein protein. 44 4e-04
BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multip... 44 4e-04
BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multip... 44 4e-04
BC039068-1|AAH39068.1| 301|Homo sapiens MGC34761 protein protein. 44 4e-04
AY572973-1|AAT77226.1| 755|Homo sapiens colon cancer secreted p... 44 4e-04
AY572972-1|AAT77225.1| 755|Homo sapiens colon cancer secreted p... 44 4e-04
AY358373-1|AAQ88739.1| 455|Homo sapiens LHPE306 protein. 44 4e-04
AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. 44 4e-04
AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multip... 44 4e-04
AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multip... 44 4e-04
AK127756-1|BAC87116.1| 725|Homo sapiens protein ( Homo sapiens ... 44 4e-04
AK122716-1|BAC85505.1| 725|Homo sapiens ember 3 (SULT1A3). pro... 44 4e-04
AK074773-1|BAC11199.1| 446|Homo sapiens protein ( Homo sapiens ... 44 4e-04
AJ536328-1|CAD60276.1| 755|Homo sapiens AMACO protein. 44 4e-04
AF521893-1|AAP80866.1| 446|Homo sapiens unnamed secretory prote... 44 4e-04
AY764262-1|AAW47409.1| 108|Homo sapiens netrin G1 isoform G1d p... 43 6e-04
AY046055-2|AAL04411.1| 2812|Homo sapiens zonadhesin splice varia... 43 6e-04
AL590427-6|CAH73385.1| 480|Homo sapiens netrin G1 protein. 43 6e-04
AL513187-6|CAH73829.1| 480|Homo sapiens netrin G1 protein. 43 6e-04
AF332977-1|AAK01433.1| 2812|Homo sapiens zonadhesin variant 3 pr... 43 6e-04
EF539882-1|ABS86974.1| 1547|Homo sapiens NRXN1-alpha protein. 43 8e-04
BC150247-1|AAI50248.1| 1496|Homo sapiens NRXN1 protein protein. 43 8e-04
AL583807-2|CAH69984.3| 1575|Homo sapiens laminin, gamma 3 protein. 43 8e-04
AL583807-1|CAH69983.1| 1587|Homo sapiens laminin, gamma 3 protein. 43 8e-04
AL355872-3|CAI39529.1| 1587|Homo sapiens laminin, gamma 3 protein. 43 8e-04
AL355872-2|CAI39530.2| 1619|Homo sapiens laminin, gamma 3 protein. 43 8e-04
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 43 8e-04
AF448856-1|AAP41924.1| 303|Homo sapiens hypothetical protein pr... 43 8e-04
AF041835-1|AAD36991.1| 1587|Homo sapiens laminin gamma 3 chain p... 43 8e-04
AC007462-1|AAF03536.1| 681|Homo sapiens unknown protein. 43 8e-04
AB208887-1|BAD92124.1| 1379|Homo sapiens laminin, gamma 3 precur... 43 8e-04
AB035356-1|BAA87821.1| 1477|Homo sapiens neurexin I-alpha protei... 43 8e-04
AB011150-1|BAA25504.2| 1542|Homo sapiens KIAA0578 protein protein. 43 8e-04
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 42 0.001
U27109-1|AAC52065.1| 1228|Homo sapiens prepromultimerin protein. 42 0.001
BC063848-1|AAH63848.1| 1228|Homo sapiens multimerin 1 protein. 42 0.001
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 42 0.001
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 42 0.001
AF428259-1|AAP97299.1| 303|Homo sapiens hypothetical protein pr... 42 0.001
AF193046-1|AAG22474.1| 277|Homo sapiens unknown protein. 42 0.001
AC093759-2|AAY40957.1| 1228|Homo sapiens unknown protein. 42 0.001
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 42 0.001
DQ431791-1|ABF68980.1| 37|Homo sapiens coagulation factor IX p... 42 0.001
AY764263-1|AAW47410.1| 88|Homo sapiens netrin G1 isoform G1e p... 42 0.001
AL590427-2|CAH73384.1| 460|Homo sapiens netrin G1 protein. 42 0.001
AL513187-2|CAH73833.1| 460|Homo sapiens netrin G1 protein. 42 0.001
AL355357-1|CAI16435.1| 95|Homo sapiens protein ( Human DNA seq... 42 0.001
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 42 0.002
D50030-1|BAA74450.1| 655|Homo sapiens hepatocyte growth factor ... 42 0.002
D14012-1|BAA03113.1| 655|Homo sapiens HGF activator precursor p... 42 0.002
BC112192-1|AAI12193.1| 655|Homo sapiens HGF activator, prepropr... 42 0.002
BC112190-1|AAI12191.1| 655|Homo sapiens HGF activator, prepropr... 42 0.002
AL590235-6|CAM21456.1| 655|Homo sapiens HGF activator protein. 42 0.002
AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 42 0.002
AF463518-1|AAL68839.1| 1311|Homo sapiens cell recognition protei... 42 0.002
AC093384-1|AAY14680.1| 92|Homo sapiens unknown protein. 42 0.002
AB100094-1|BAC55272.1| 1308|Homo sapiens hypothetical protein pr... 42 0.002
AB100093-1|BAC55271.1| 1235|Homo sapiens hypothetical protein pr... 42 0.002
AB100092-1|BAC55270.1| 1260|Homo sapiens hypothetical protein pr... 42 0.002
AB051550-1|BAB21854.2| 1322|Homo sapiens KIAA1763 protein protein. 42 0.002
Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)... 41 0.002
U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain pro... 41 0.002
EF025894-1|ABJ98522.1| 2721|Homo sapiens zonadhesin isoform 6 pr... 41 0.002
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 41 0.002
AY046055-1|AAL04413.1| 2721|Homo sapiens zonadhesin splice varia... 41 0.002
AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (meros... 41 0.002
AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (meros... 41 0.002
AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (meros... 41 0.002
AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (meros... 41 0.002
AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (meros... 41 0.002
AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (meros... 41 0.002
AF332980-1|AAK01436.1| 2721|Homo sapiens zonadhesin variant 6 pr... 41 0.002
AK125557-1|BAC86201.1| 531|Homo sapiens protein ( Homo sapiens ... 41 0.003
X71923-1|CAA50739.1| 750|Homo sapiens tenascin-X precursor prot... 40 0.004
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein. 40 0.004
BC150275-1|AAI50276.1| 1642|Homo sapiens neurexin 2 protein. 40 0.004
BC045172-1|AAH45172.2| 749|Homo sapiens LAMB4 protein protein. 40 0.004
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein. 40 0.004
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein. 40 0.004
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein. 40 0.004
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein. 40 0.004
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein. 40 0.004
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB... 40 0.004
AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain pr... 40 0.004
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 40 0.004
AC044790-1|AAK68154.1| 1712|Homo sapiens NRXN2 protein. 40 0.004
AB177862-1|BAD66840.1| 1434|Homo sapiens KIAA0921 splice variant... 40 0.004
AB035266-1|BAA94075.1| 1712|Homo sapiens neurexin II protein. 40 0.004
AB023138-1|BAA76765.2| 1658|Homo sapiens KIAA0921 protein protein. 40 0.004
X13097-1|CAA31489.1| 291|Homo sapiens plasminogen activator pre... 40 0.005
X07393-1|CAA30302.1| 562|Homo sapiens protein ( Human fetal lun... 40 0.005
M18182-1|AAA36800.1| 562|Homo sapiens protein ( Human plasminog... 40 0.005
M15518-1|AAA60111.1| 562|Homo sapiens tissue-type plasminogen a... 40 0.005
K03021-1|AAA98809.1| 562|Homo sapiens plasminogen activator pro... 40 0.005
D01096-1|BAA00881.1| 532|Homo sapiens tissue plasminogen activa... 40 0.005
BT007060-1|AAP35709.1| 562|Homo sapiens plasminogen activator, ... 40 0.005
BC142619-1|AAI42620.1| 772|Homo sapiens LAMB4 protein protein. 40 0.005
BC095403-1|AAH95403.1| 562|Homo sapiens plasminogen activator, ... 40 0.005
BC089434-1|AAH89434.1| 737|Homo sapiens regeneration associated... 40 0.005
BC018636-1|AAH18636.3| 562|Homo sapiens plasminogen activator, ... 40 0.005
BC013968-1|AAH13968.3| 562|Homo sapiens plasminogen activator, ... 40 0.005
BC007231-1|AAH07231.1| 562|Homo sapiens plasminogen activator, ... 40 0.005
AY291060-1|AAP34246.1| 291|Homo sapiens plasminogen activator, ... 40 0.005
AY221101-1|AAO34406.1| 562|Homo sapiens tissue plasminogen acti... 40 0.005
AL138836-3|CAC22313.2| 602|Homo sapiens multiple EGF-like-domai... 40 0.005
AK057327-1|BAB71429.1| 721|Homo sapiens protein ( Homo sapiens ... 40 0.005
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 40 0.005
AF172277-3|AAF22284.1| 761|Homo sapiens laminin beta 1 related ... 40 0.005
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 40 0.005
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 40 0.007
AY764266-1|AAW47413.1| 133|Homo sapiens netrin G1 isoform G1n p... 40 0.007
AY764264-1|AAW47411.1| 57|Homo sapiens netrin G1 isoform G1l p... 40 0.007
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 40 0.007
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 40 0.007
BC000059-1|AAH00059.2| 771|Homo sapiens CELSR1 protein protein. 39 0.009
AY781194-1|AAW47415.1| 111|Homo sapiens netrin G1 isoform G1b p... 39 0.009
AY764267-1|AAW47414.1| 153|Homo sapiens netrin G1 isoform G1o p... 39 0.009
AY764265-1|AAW47412.1| 209|Homo sapiens netrin G1 isoform G1m p... 39 0.009
AY764260-1|AAW47407.1| 167|Homo sapiens netrin G1 isoform G1a p... 39 0.009
AL590427-3|CAH73381.1| 539|Homo sapiens netrin G1 protein. 39 0.009
AL513187-3|CAH73830.1| 539|Homo sapiens netrin G1 protein. 39 0.009
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein. 39 0.009
AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type... 39 0.009
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr... 39 0.009
AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein. 39 0.009
AB011105-1|BAA25459.1| 1645|Homo sapiens KIAA0533 protein protein. 39 0.009
CR788268-5|CAI95050.1| 1288|Homo sapiens contactin associated pr... 39 0.012
CR788268-4|CAI95048.1| 746|Homo sapiens contactin associated pr... 39 0.012
CR788268-2|CAI95046.1| 1175|Homo sapiens contactin associated pr... 39 0.012
BX664735-4|CAI16326.1| 1288|Homo sapiens contactin associated pr... 39 0.012
BX664735-3|CAI95321.1| 746|Homo sapiens contactin associated pr... 39 0.012
BX664735-1|CAI16324.1| 1175|Homo sapiens contactin associated pr... 39 0.012
BX649569-4|CAI12628.1| 1288|Homo sapiens contactin associated pr... 39 0.012
BX649569-3|CAI94998.1| 746|Homo sapiens contactin associated pr... 39 0.012
BX649569-1|CAI12626.1| 1175|Homo sapiens contactin associated pr... 39 0.012
BC132737-1|AAI32738.1| 1207|Homo sapiens CNTNAP3 protein protein. 39 0.012
BC030220-1|AAH30220.1| 438|Homo sapiens netrin G1 protein. 39 0.012
AY764261-1|AAW47408.1| 66|Homo sapiens netrin G1 isoform G1c p... 39 0.012
AY358365-1|AAQ88731.1| 438|Homo sapiens YLSR571 protein. 39 0.012
AL590427-5|CAH73382.1| 494|Homo sapiens netrin G1 protein. 39 0.012
AL590427-4|CAH73383.1| 438|Homo sapiens netrin G1 protein. 39 0.012
AL513187-5|CAH73831.1| 494|Homo sapiens netrin G1 protein. 39 0.012
AL513187-4|CAH73832.1| 438|Homo sapiens netrin G1 protein. 39 0.012
AL353729-6|CAH72042.1| 1039|Homo sapiens contactin associated pr... 39 0.012
AL353729-3|CAH72039.1| 1288|Homo sapiens contactin associated pr... 39 0.012
AL353729-2|CAH72037.1| 745|Homo sapiens contactin associated pr... 39 0.012
AL162501-4|CAH70490.1| 1039|Homo sapiens contactin associated pr... 39 0.012
AL162501-2|CAH70488.1| 1288|Homo sapiens contactin associated pr... 39 0.012
AL162501-1|CAH70485.1| 745|Homo sapiens contactin associated pr... 39 0.012
AK056833-1|BAB71293.1| 745|Homo sapiens protein ( Homo sapiens ... 39 0.012
AK027841-1|BAB55404.1| 737|Homo sapiens protein ( Homo sapiens ... 39 0.012
AF333769-1|AAG52889.2| 1288|Homo sapiens cell recognition molecu... 39 0.012
AB051501-1|BAB21805.2| 1175|Homo sapiens KIAA1714 protein protein. 39 0.012
X79683-1|CAA56130.1| 1798|Homo sapiens beta2/S laminin chain pro... 38 0.016
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 38 0.016
S83182-1|AAB46909.1| 560|Homo sapiens hyaluronan-binding protei... 38 0.016
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 38 0.016
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 38 0.016
D49742-1|BAA08576.1| 560|Homo sapiens HGF activator like protei... 38 0.016
BC113373-1|AAI13374.1| 1331|Homo sapiens contactin associated pr... 38 0.016
BC093780-1|AAH93780.1| 1331|Homo sapiens contactin associated pr... 38 0.016
BC031412-1|AAH31412.1| 560|Homo sapiens hyaluronan binding prot... 38 0.016
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 38 0.016
AY534754-1|AAS16352.1| 560|Homo sapiens hyaluronan binding prot... 38 0.016
AL390197-1|CAH71108.1| 560|Homo sapiens hyaluronan binding prot... 38 0.016
AF319045-1|AAK34932.1| 1331|Homo sapiens contactin-associated pr... 38 0.016
AF193613-1|AAF25199.1| 1331|Homo sapiens cell recognition molecu... 38 0.016
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 38 0.016
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 38 0.016
AB020675-1|BAA74891.1| 1339|Homo sapiens KIAA0868 protein protein. 38 0.016
U17760-1|AAC51352.1| 1172|Homo sapiens laminin S B3 chain protein. 38 0.021
M59303-1|AAA36499.1| 320|Homo sapiens protein Z protein. 38 0.021
M55671-1|AAA36501.1| 422|Homo sapiens protein Z protein. 38 0.021
M55670-1|AAA36500.1| 400|Homo sapiens protein Z protein. 38 0.021
M13232-2|AAA88041.1| 444|Homo sapiens protein ( Human factor VI... 38 0.021
M13232-1|AAA88040.1| 466|Homo sapiens coagulation factor VII pr... 38 0.021
L25541-1|AAA61834.1| 1170|Homo sapiens laminin S B3 chain protein. 38 0.021
J02933-1|AAA51983.1| 466|Homo sapiens protein ( Human blood coa... 38 0.021
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 38 0.021
D37766-1|BAA22263.1| 1172|Homo sapiens Laminin-5 beta3 chain pro... 38 0.021
DQ142911-1|ABD17891.1| 466|Homo sapiens cogulation factor VII p... 38 0.021
BC130468-1|AAI30469.1| 444|Homo sapiens coagulation factor VII ... 38 0.021
BC126315-1|AAI26316.1| 1224|Homo sapiens MUC17 protein protein. 38 0.021
>BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 75.8 bits (178), Expect = 9e-14
Identities = 40/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G Q S+ C C NGG CS + C C PGY G C+ R+ + P P
Sbjct: 303 EECPFGSFG-FQCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLP 361
Query: 389 C--------SLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C S HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 362 CPCDADNTISCHPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 406
Score = 70.9 bits (166), Expect = 2e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 433
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 240
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C CP G+ GA C P G
Sbjct: 241 --HHITGECACPPGWTGAVCAQPCPPG 265
Score = 62.9 bits (146), Expect = 7e-10
Identities = 29/86 (33%), Positives = 40/86 (46%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 460
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
++ +C C G+ G C +P G
Sbjct: 461 ---VDGSCTCKEGWQGLDCTLPCPSG 483
Score = 56.0 bits (129), Expect = 8e-08
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 430
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 232 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 283
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C C GY G CQ G
Sbjct: 284 ---DHVTGQCHCTAGYMGDRCQEECPFG 308
Score = 55.2 bits (127), Expect = 1e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 585
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
+C P+ S C+C G+ G CQ
Sbjct: 586 SCSPEDGS-----CECAPGFRGPLCQ 606
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 576 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 630
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
P + ++ C+C G++GA C
Sbjct: 631 PCHH--ISGICECLPGFSGALC 650
Score = 53.2 bits (122), Expect = 5e-07
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 430
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 709 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 761
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
++ C C G+ G C+
Sbjct: 762 ---DHISGKCTCRTGFTGQHCE 780
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 433
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 804
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+ TC C G+ G C
Sbjct: 805 --DHVTGTCYCSPGFKGIRC 822
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 197
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P C C GY G C+
Sbjct: 198 DPRAGE-----CLCAPGYTGVYCE 216
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/85 (30%), Positives = 37/85 (43%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 447 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 502
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMP 502
P ++ +C C G+ G +C++P
Sbjct: 503 P-----IDGSCSCTPGWLGDTCELP 522
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 272 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 326
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + C+C GY G CQ
Sbjct: 327 SPTTGA-----CECEPGYKGPRCQ 345
Score = 46.8 bits (106), Expect = 5e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 541
Query: 416 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 499
C P W CD CP G G +C +
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 421
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 664 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 717
Query: 422 CKPDRNSWMNHTCDCPLGYAGASC 493
C + + C C G+ G C
Sbjct: 718 CSAE-----DGACHCTPGWTGLFC 736
Score = 33.5 bits (73), Expect = 0.46
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C+C N +C + C C PG+ G C+
Sbjct: 796 CECMNNSTCDHVTGTCYCSPGFKGIRCD 823
>BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 75.8 bits (178), Expect = 9e-14
Identities = 40/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G Q S+ C C NGG CS + C C PGY G C+ R+ + P P
Sbjct: 303 EECPFGSFG-FQCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLP 361
Query: 389 C--------SLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C S HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 362 CPCDADNTISCHPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 406
Score = 70.9 bits (166), Expect = 2e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 433
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 240
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C CP G+ GA C P G
Sbjct: 241 --HHITGECACPPGWTGAVCAQPCPPG 265
Score = 62.9 bits (146), Expect = 7e-10
Identities = 29/86 (33%), Positives = 40/86 (46%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 460
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
++ +C C G+ G C +P G
Sbjct: 461 ---VDGSCTCKEGWQGLDCTLPCPSG 483
Score = 56.0 bits (129), Expect = 8e-08
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 430
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 232 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 283
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C C GY G CQ G
Sbjct: 284 ---DHVTGQCHCTAGYMGDRCQEECPFG 308
Score = 55.2 bits (127), Expect = 1e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 585
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
+C P+ S C+C G+ G CQ
Sbjct: 586 SCSPEDGS-----CECAPGFRGPLCQ 606
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 576 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 630
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
P + ++ C+C G++GA C
Sbjct: 631 PCHH--ISGICECLPGFSGALC 650
Score = 53.2 bits (122), Expect = 5e-07
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 430
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 709 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 761
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
++ C C G+ G C+
Sbjct: 762 ---DHISGKCTCRTGFTGQHCE 780
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 433
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 804
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+ TC C G+ G C
Sbjct: 805 --DHVTGTCYCSPGFKGIRC 822
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 197
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P C C GY G C+
Sbjct: 198 DPRAGE-----CLCAPGYTGVYCE 216
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/85 (30%), Positives = 37/85 (43%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 447 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 502
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMP 502
P ++ +C C G+ G +C++P
Sbjct: 503 P-----IDGSCSCTPGWLGDTCELP 522
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 272 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 326
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + C+C GY G CQ
Sbjct: 327 SPTTGA-----CECEPGYKGPRCQ 345
Score = 46.8 bits (106), Expect = 5e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 541
Query: 416 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 499
C P W CD CP G G +C +
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 421
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 664 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 717
Query: 422 CKPDRNSWMNHTCDCPLGYAGASC 493
C + + C C G+ G C
Sbjct: 718 CSAE-----DGACHCTPGWTGLFC 736
Score = 33.5 bits (73), Expect = 0.46
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C+C N +C + C C PG+ G C+
Sbjct: 796 CECMNNSTCDHVTGTCYCSPGFKGIRCD 823
>AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein
protein.
Length = 626
Score = 75.8 bits (178), Expect = 9e-14
Identities = 40/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G Q S+ C C NGG CS + C C PGY G C+ R+ + P P
Sbjct: 54 EECPFGSFG-FQCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLP 112
Query: 389 C--------SLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C S HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 113 CPCDADNTISCHPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 157
Score = 62.9 bits (146), Expect = 7e-10
Identities = 29/86 (33%), Positives = 40/86 (46%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 158 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 211
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
++ +C C G+ G C +P G
Sbjct: 212 ---VDGSCTCKEGWQGLDCTLPCPSG 234
Score = 55.2 bits (127), Expect = 1e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 281 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 336
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
+C P+ S C+C G+ G CQ
Sbjct: 337 SCSPEDGS-----CECAPGFRGPLCQ 357
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 327 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 381
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
P + ++ C+C G++GA C
Sbjct: 382 PCHH--ISGICECLPGFSGALC 401
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/85 (30%), Positives = 37/85 (43%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 198 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 253
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMP 502
P ++ +C C G+ G +C++P
Sbjct: 254 P-----IDGSCSCTPGWLGDTCELP 273
Score = 50.4 bits (115), Expect = 4e-06
Identities = 21/48 (43%), Positives = 25/48 (52%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
+C C NG SCS E C C PG+TG +C R L S P + C L
Sbjct: 460 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRKPHLLASQPLRIPCCGL 507
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 23 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 77
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + C+C GY G CQ
Sbjct: 78 SPTTGA-----CECEPGYKGPRCQ 96
Score = 46.8 bits (106), Expect = 5e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 238 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 292
Query: 416 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 499
C P W CD CP G G +C +
Sbjct: 293 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 328
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 421
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 415 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 468
Query: 422 CKPDRNSWMNHTCDCPLGYAGASC 493
C + + C C G+ G C
Sbjct: 469 CSAE-----DGACHCTPGWTGLFC 487
>AB300051-1|BAF64841.1| 1044|Homo sapiens MEGF11 protein.
Length = 1044
Score = 75.8 bits (178), Expect = 9e-14
Identities = 40/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G Q S+ C C NGG CS + C C PGY G C+ R+ + P P
Sbjct: 303 EECPFGSFG-FQCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLP 361
Query: 389 C--------SLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C S HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 362 CPCDADNTISCHPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 406
Score = 70.9 bits (166), Expect = 2e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 433
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 240
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C CP G+ GA C P G
Sbjct: 241 --HHITGECACPPGWTGAVCAQPCPPG 265
Score = 62.9 bits (146), Expect = 7e-10
Identities = 29/86 (33%), Positives = 40/86 (46%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 460
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
++ +C C G+ G C +P G
Sbjct: 461 ---VDGSCTCKEGWQGLDCTLPCPSG 483
Score = 56.0 bits (129), Expect = 8e-08
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 430
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 232 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 283
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C C GY G CQ G
Sbjct: 284 ---DHVTGQCHCTAGYMGDRCQEECPFG 308
Score = 55.2 bits (127), Expect = 1e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 585
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
+C P+ S C+C G+ G CQ
Sbjct: 586 SCSPEDGS-----CECAPGFRGPLCQ 606
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 576 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 630
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
P + ++ C+C G++GA C
Sbjct: 631 PCHH--ISGICECLPGFSGALC 650
Score = 53.2 bits (122), Expect = 5e-07
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 430
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 709 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 761
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
++ C C G+ G C+
Sbjct: 762 ---DHISGKCTCRTGFTGQHCE 780
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 433
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 804
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+ TC C G+ G C
Sbjct: 805 --DHVTGTCYCSPGFKGIRC 822
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 197
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P C C GY G C+
Sbjct: 198 DPRAGE-----CLCAPGYTGVYCE 216
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/85 (30%), Positives = 37/85 (43%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 447 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 502
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMP 502
P ++ +C C G+ G +C++P
Sbjct: 503 P-----IDGSCSCTPGWLGDTCELP 522
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 272 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 326
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + C+C GY G CQ
Sbjct: 327 SPTTGA-----CECEPGYKGPRCQ 345
Score = 46.8 bits (106), Expect = 5e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 541
Query: 416 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 499
C P W CD CP G G +C +
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 421
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 664 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 717
Query: 422 CKPDRNSWMNHTCDCPLGYAGASC 493
C + + C C G+ G C
Sbjct: 718 CSAE-----DGACHCTPGWTGLFC 736
Score = 33.5 bits (73), Expect = 0.46
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C+C N +C + C C PG+ G C+
Sbjct: 796 CECMNNSTCDHVTGTCYCSPGFKGIRCD 823
>AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA1781)
protein.
Length = 969
Score = 75.8 bits (178), Expect = 9e-14
Identities = 40/108 (37%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G Q S+ C C NGG CS + C C PGY G C+ R+ + P P
Sbjct: 228 EECPFGSFG-FQCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLP 286
Query: 389 C--------SLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C S HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 287 CPCDADNTISCHPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 331
Score = 70.9 bits (166), Expect = 2e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 433
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 114 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 165
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C CP G+ GA C P G
Sbjct: 166 --HHITGECACPPGWTGAVCAQPCPPG 190
Score = 62.9 bits (146), Expect = 7e-10
Identities = 29/86 (33%), Positives = 40/86 (46%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 332 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 385
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
++ +C C G+ G C +P G
Sbjct: 386 ---VDGSCTCKEGWQGLDCTLPCPSG 408
Score = 56.0 bits (129), Expect = 8e-08
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 430
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 157 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 208
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
+ C C GY G CQ G
Sbjct: 209 ---DHVTGQCHCTAGYMGDRCQEECPFG 233
Score = 55.2 bits (127), Expect = 1e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 455 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 510
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
+C P+ S C+C G+ G CQ
Sbjct: 511 SCSPEDGS-----CECAPGFRGPLCQ 531
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 501 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 555
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
P + ++ C+C G++GA C
Sbjct: 556 PCHH--ISGICECLPGFSGALC 575
Score = 53.2 bits (122), Expect = 5e-07
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 430
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 634 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 686
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
++ C C G+ G C+
Sbjct: 687 ---DHISGKCTCRTGFTGQHCE 705
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 433
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 678 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 729
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+ TC C G+ G C
Sbjct: 730 --DHVTGTCYCSPGFKGIRC 747
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 68 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 122
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P C C GY G C+
Sbjct: 123 DPRAGE-----CLCAPGYTGVYCE 141
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/85 (30%), Positives = 37/85 (43%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 372 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 427
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMP 502
P ++ +C C G+ G +C++P
Sbjct: 428 P-----IDGSCSCTPGWLGDTCELP 447
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 424
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 197 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 251
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + C+C GY G CQ
Sbjct: 252 SPTTGA-----CECEPGYKGPRCQ 270
Score = 46.8 bits (106), Expect = 5e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 412 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 466
Query: 416 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 499
C P W CD CP G G +C +
Sbjct: 467 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 502
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 421
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 589 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 642
Query: 422 CKPDRNSWMNHTCDCPLGYAGASC 493
C + + C C G+ G C
Sbjct: 643 CSAE-----DGACHCTPGWTGLFC 661
Score = 33.5 bits (73), Expect = 0.46
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C+C N +C + C C PG+ G C+
Sbjct: 721 CECMNNSTCDHVTGTCYCSPGFKGIRCD 748
>BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophila)
protein.
Length = 685
Score = 71.3 bits (167), Expect = 2e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 60.9 bits (141), Expect = 3e-09
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ + H C CP GY G C+
Sbjct: 343 EDGY--H-CLCPPGYYGLHCE 360
Score = 57.2 bits (132), Expect = 3e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATCS--NSGQRS 307
Query: 452 HTCDCPLGYAGASCQMPL 505
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein.
Length = 685
Score = 71.3 bits (167), Expect = 2e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 60.9 bits (141), Expect = 3e-09
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ + H C CP GY G C+
Sbjct: 343 EDGY--H-CLCPPGYYGLHCE 360
Score = 57.2 bits (132), Expect = 3e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATCS--NSGQRS 307
Query: 452 HTCDCPLGYAGASCQMPL 505
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein.
Length = 653
Score = 71.3 bits (167), Expect = 2e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 292 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 340
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 341 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 372
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 379 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 427
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N M C CP G++G C++
Sbjct: 428 NGLM---CTCPAGFSGRRCEV 445
Score = 60.9 bits (141), Expect = 3e-09
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 262 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 310
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ + H C CP GY G C+
Sbjct: 311 EDGY--H-CLCPPGYYGLHCE 328
Score = 57.2 bits (132), Expect = 3e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 417 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 467
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++ C+CP G+ G+ C+ P+ L S
Sbjct: 468 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 494
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 339 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 385
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
N + C C G+ G C++
Sbjct: 386 -LNRGPSRMCRCRPGFTGTYCEL 407
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 230 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATCS--NSGQRS 275
Query: 452 HTCDCPLGYAGASCQMPL 505
+TC C GY G C++ L
Sbjct: 276 YTCTCRPGYTGVDCELEL 293
>AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein.
Length = 685
Score = 71.3 bits (167), Expect = 2e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 60.9 bits (141), Expect = 3e-09
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ + H C CP GY G C+
Sbjct: 343 EDGY--H-CLCPPGYYGLHCE 360
Score = 57.2 bits (132), Expect = 3e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATCS--NSGQRS 307
Query: 452 HTCDCPLGYAGASCQMPL 505
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein.
Length = 685
Score = 71.3 bits (167), Expect = 2e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 60.9 bits (141), Expect = 3e-09
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ + H C CP GY G C+
Sbjct: 343 EDGY--H-CLCPPGYYGLHCE 360
Score = 57.2 bits (132), Expect = 3e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATCS--NSGQRS 307
Query: 452 HTCDCPLGYAGASCQMPL 505
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2
protein.
Length = 685
Score = 71.3 bits (167), Expect = 2e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 60.9 bits (141), Expect = 3e-09
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ + H C CP GY G C+
Sbjct: 343 EDGY--H-CLCPPGYYGLHCE 360
Score = 57.2 bits (132), Expect = 3e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 2e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATCS--NSGQRS 307
Query: 452 HTCDCPLGYAGASCQMPL 505
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 611 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 659
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 660 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 689
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 444 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 492
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 493 INRFQ---CLCPTGFSGNLCQLDID 514
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 728 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 776
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 777 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 813
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 474 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 522
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 523 NGAQC---YNRASDYFCKCPEDYEGKNC 547
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 586 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 634
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 635 VNS---YKCICSDGWEGAYCE 652
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 293 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 339
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 340 -ETSLGFECECSPGWTGPTCSTNID 363
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 332 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 380
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 381 NGF---KCVCPPQWTGKTCQL 398
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 693 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 741
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 742 NGGTCVVNGESF---TCVCKEGWEGPIC 766
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 370 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 415
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 416 NLIASYYCDCLPGWMGQNCDININDCLGQ 444
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 778 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 826
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 827 NGYR---CVCPPGHSGAKCQ 843
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 261 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 306
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 307 ---YQCSCPEGYSGPNCEI 322
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 663 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 711
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 712 DAF---KCMCPGGWEGTTCNI 729
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 512 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 571
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 572 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 613
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 805 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 849
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 850 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 880
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 70.5 bits (165), Expect = 3e-12
Identities = 35/80 (43%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S C+CPPG+TGSYC+ VN C PC GGTC+ R
Sbjct: 993 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HVVNECDSRPCLLGGTCQDGR 1041
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
H C CP GY G +CQ
Sbjct: 1042 GL---HRCTCPQGYTGPNCQ 1058
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 908 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 955
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
RNG C +S +TC CP G++G C+
Sbjct: 956 RNGANCTDCVDS---YTCTCPAGFSGIHCE 982
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 941 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 989
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 990 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1020
Score = 56.4 bits (130), Expect = 6e-08
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL-ELGQ 517
S++ C CP + G +C+ + E GQ
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQ 184
Score = 56.4 bits (130), Expect = 6e-08
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +2
Query: 251 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNI-----------NECASNPCLNKGTC 806
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPL 505
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCR GTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRLRGTCQDPDNAYL---CFCLKGTTGPNCEINLD 643
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP-D 433
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.4 bits (125), Expect = 2e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C++G +C + C C PGYTGS C + I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNSNI-----------DECAGNPCHNGGTCE 694
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 430
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCPCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 3e-07
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + + +S C GG+C C CP GYTG C+ V+ C
Sbjct: 1017 SYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNL-----------VHWCD 1065
Query: 395 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 502
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1066 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1098
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1117 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1162
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G +C ++
Sbjct: 1163 DYLGGYSCKCVAGYHGVNCSEEID 1186
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1267 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1315
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1316 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1347
Score = 53.2 bits (122), Expect = 5e-07
Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC D + + C CP G++G SCQ
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQ 139
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPP-GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C ES +C+CP G G CE I N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDI-----------NECVLSPCRHGASC- 885
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+N+ + C C GY+G +C+ ++
Sbjct: 886 --QNTHGXYRCHCQAGYSGRNCETDID 910
Score = 49.6 bits (113), Expect = 7e-06
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+N +C + C+C PGY G +CE + C+ PC
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVN-----------TDECASSPCL 500
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ G C N + C+CP G+ G CQ ++
Sbjct: 501 HNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1155 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1203
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N+ + C CP G G C++ ++
Sbjct: 1204 NT---YKCSCPRGTQGVHCEINVD 1224
Score = 47.6 bits (108), Expect = 3e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 870 DINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 918
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N+ CDC G+ G C+
Sbjct: 919 NGGSCTDGINTAF---CDCLPGFRGTFCE 944
Score = 47.2 bits (107), Expect = 3e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 406
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1349 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1398
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N GTC+P S + C CP + G C +
Sbjct: 1399 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1428
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NGG+C C C PG+TG CE I + C + C+NGG C
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------DDCPGNNCKNGGACVDG 275
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 276 VNT---YNCPCPPEWTGQYC 292
Score = 46.8 bits (106), Expect = 5e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 46.8 bits (106), Expect = 5e-05
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQMPL 505
NGG C+ + + + +C CP G G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTAGAKGQTCEVDI 871
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C S C C PG++G+ C+ N C +PC NGGTCK D S +
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTSGI 775
Query: 449 NHTCDCPLGYAGASCQ 496
C C G++G +CQ
Sbjct: 776 --VCTCREGFSGPNCQ 789
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 424
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 2e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C C GY G C++
Sbjct: 472 GEFQ---CMCMPGYEGVHCEV 489
Score = 44.0 bits (99), Expect = 3e-04
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Frame = +2
Query: 203 NIQECNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPP 376
N+ +CN S S +C N G+C + +C CPPG+ G CE
Sbjct: 1222 NVDDCNPPVD---PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------G 1267
Query: 377 PVNPCSLHPCRNGGT--CKPDRNSWMNHTCDCPLGYAGASCQ 496
VN C +PC GT C N + H C+C G+ G C+
Sbjct: 1268 DVNECLSNPCDARGTQNCVQRVNDF--H-CECRAGHTGRRCE 1306
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 32.3 bits (70), Expect = 1.1
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C G+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ GTC + + C C GY G+ C ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNSNID 680
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 34.7 bits (76), Expect = 0.20
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
R +I +S C G +C E C+CPPG++G+ C+
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 70.5 bits (165), Expect = 3e-12
Identities = 35/80 (43%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S C+CPPG+TGSYC+ VN C PC GGTC+ R
Sbjct: 993 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HVVNECDSRPCLLGGTCQDGR 1041
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
H C CP GY G +CQ
Sbjct: 1042 GL---HRCTCPQGYTGPNCQ 1058
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 908 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 955
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
RNG C +S +TC CP G++G C+
Sbjct: 956 RNGANCTDCVDS---YTCTCPAGFSGIHCE 982
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 941 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 989
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 990 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1020
Score = 56.4 bits (130), Expect = 6e-08
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL-ELGQ 517
S++ C CP + G +C+ + E GQ
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQ 184
Score = 56.4 bits (130), Expect = 6e-08
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +2
Query: 251 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNI-----------NECASNPCLNKGTC 806
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPL 505
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCR GTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRLRGTCQDPDNAYL---CFCLKGTTGPNCEINLD 643
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP-D 433
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.4 bits (125), Expect = 2e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C++G +C + C C PGYTGS C + I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNSNI-----------DECAGNPCHNGGTCE 694
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 430
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCPCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 3e-07
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + + +S C GG+C C CP GYTG C+ V+ C
Sbjct: 1017 SYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNL-----------VHWCD 1065
Query: 395 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 502
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1066 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1098
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1117 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1162
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G +C ++
Sbjct: 1163 DYLGGYSCKCVAGYHGVNCSEEID 1186
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1267 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1315
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1316 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1347
Score = 53.2 bits (122), Expect = 5e-07
Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC D + + C CP G++G SCQ
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQ 139
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPP-GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C ES +C+CP G G CE I N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDI-----------NECVLSPCRHGASC- 885
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+N+ + C C GY+G +C+ ++
Sbjct: 886 --QNTHGXYRCHCQAGYSGRNCETDID 910
Score = 49.6 bits (113), Expect = 7e-06
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+N +C + C+C PGY G +CE + C+ PC
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVN-----------TDECASSPCL 500
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ G C N + C+CP G+ G CQ ++
Sbjct: 501 HNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1155 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1203
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N+ + C CP G G C++ ++
Sbjct: 1204 NT---YKCSCPRGTQGVHCEINVD 1224
Score = 47.6 bits (108), Expect = 3e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 870 DINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 918
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N+ CDC G+ G C+
Sbjct: 919 NGGSCTDGINTAF---CDCLPGFRGTFCE 944
Score = 47.2 bits (107), Expect = 3e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 406
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1349 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1398
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N GTC+P S + C CP + G C +
Sbjct: 1399 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1428
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NGG+C C C PG+TG CE I + C + C+NGG C
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------DDCPGNNCKNGGACVDG 275
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 276 VNT---YNCPCPPEWTGQYC 292
Score = 46.8 bits (106), Expect = 5e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 46.8 bits (106), Expect = 5e-05
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQMPL 505
NGG C+ + + + +C CP G G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTAGAKGQTCEVDI 871
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C S C C PG++G+ C+ N C +PC NGGTCK D S +
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTSGI 775
Query: 449 NHTCDCPLGYAGASCQ 496
C C G++G +CQ
Sbjct: 776 --VCTCREGFSGPNCQ 789
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 424
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 2e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C C GY G C++
Sbjct: 472 GEFQ---CMCMPGYEGVHCEV 489
Score = 44.0 bits (99), Expect = 3e-04
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Frame = +2
Query: 203 NIQECNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPP 376
N+ +CN S S +C N G+C + +C CPPG+ G CE
Sbjct: 1222 NVDDCNPPVD---PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------G 1267
Query: 377 PVNPCSLHPCRNGGT--CKPDRNSWMNHTCDCPLGYAGASCQ 496
VN C +PC GT C N + H C+C G+ G C+
Sbjct: 1268 DVNECLSNPCDARGTQNCVQRVNDF--H-CECRAGHTGRRCE 1306
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 32.3 bits (70), Expect = 1.1
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C G+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ GTC + + C C GY G+ C ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNSNID 680
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 5e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 3e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 61.3 bits (142), Expect = 2e-09
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC+N SC CICPPGY G +CE ++ C+ +PC +GG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLDGGHCQNE 505
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 3e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +2
Query: 236 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.0 bits (119), Expect = 1e-06
Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
NS + C C G+ GA C+
Sbjct: 648 VNS---YKCICSDGWEGAYCE 665
Score = 50.4 bits (115), Expect = 4e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +GG C E C+CP G++G+ C+ I + C +PC+
Sbjct: 487 DIDECASNPCLDGGHCQNEINRFQCLCPTGFSGNLCQLDI-----------DYCEPNPCQ 535
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 7e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.6 bits (113), Expect = 7e-06
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D Q E+ C NGG+C E + C+CP G+ G+ C IA + C +PC
Sbjct: 706 DSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SSCLPNPCH 754
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC + S+ TC C G+ G C
Sbjct: 755 NGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 517
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 442
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 443 WMNHTCDCPLGYAGASCQM 499
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.049
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 361
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 362 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat
protein protein.
Length = 4590
Score = 69.7 bits (163), Expect = 6e-12
Identities = 49/162 (30%), Positives = 73/162 (45%), Gaps = 9/162 (5%)
Frame = +2
Query: 41 ESLRFETPMFVGG-VDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKS-SNIQE 214
++L + +F GG + + V GF GC+ + LN + +NS +S ++I+E
Sbjct: 3944 KTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEE 4003
Query: 215 CNTYDRGD-IQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP 373
G + A+E C C+NGG C+ C C Y G++CE
Sbjct: 4004 SVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEIS--------- 4054
Query: 374 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
VNPCS +PC GGTC D ++ C C Y G CQ+
Sbjct: 4055 --VNPCSSNPCLYGGTCVVDNGGFV---CQCRGLYTGQRCQL 4091
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NGG+C S + C C G+ G C++ I + CS +PC +G C+
Sbjct: 4100 CKNGGTCFDSLDGAVCQCDSGFRGERCQSDI-----------DECSGNPCLHGALCE--- 4145
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N+ ++ C+C Y G C+
Sbjct: 4146 NTHGSYHCNCSHEYRGRHCE 4165
Score = 41.5 bits (93), Expect = 0.002
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C GG+C ++ C C YTG C+ +SP C PC+N
Sbjct: 4055 VNPCSSNPCLYGGTCVVDNGGFVCQCRGLYTGQRCQ-------LSPY-----CKDEPCKN 4102
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
GGTC +S C C G+ G CQ ++
Sbjct: 4103 GGTC---FDSLDGAVCQCDSGFRGERCQSDID 4131
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/39 (41%), Positives = 17/39 (43%), Gaps = 1/39 (2%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSW-MNHTCDCPLGYAG 484
PP + C PC G C D W HTC CP G G
Sbjct: 3790 PPVHHGCEDDPCPEGSECVSD--PWEEKHTCVCPSGRFG 3826
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 69.7 bits (163), Expect = 6e-12
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 424
+ CQC+NG +C + C CPPGYTG++CE + PP P C PC+NGG C
Sbjct: 193 QRCQCQNGATCDHVTGECRCPPGYTGAFCED------LCPPGKHGPQCEQRCPCQNGGVC 246
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
+ C CP G+ G C P G+
Sbjct: 247 -----HHVTGECSCPSGWMGTVCGQPCPEGR 272
Score = 55.2 bits (127), Expect = 1e-07
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPCRNGGT 421
S+ CQC NGG+C + C C PGYTG C E + +Y V C NGG
Sbjct: 278 SQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTY------GVLCAETCQCVNGGK 331
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C ++ C C G+AG C+ L
Sbjct: 332 C-----YHVSGACLCEAGFAGERCEARL 354
Score = 53.2 bits (122), Expect = 5e-07
Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)
Frame = +2
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLM--------S 367
EC G + +E+CQC NGG C S C+C G+ G CE R+ +
Sbjct: 310 ECPVGTYG-VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC 368
Query: 368 PPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQ 496
P N S HP CKP W C+ C G+ G +CQ
Sbjct: 369 PCHLENTHSCHPMSGECACKP---GWSGLYCNETCSPGFYGEACQ 410
Score = 51.2 bits (117), Expect = 2e-06
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 1/120 (0%)
Frame = +2
Query: 140 CIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTNCICPPG 319
C+ + N +N D + CQC+NG C+ + C C G
Sbjct: 113 CVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAG 172
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G CE R N C C+NG TC + C CP GY GA C+
Sbjct: 173 FRGWRCEDRCEQGTYG-----NDCHQRCQCQNGATC-----DHVTGECRCPPGYTGAFCE 222
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 1/92 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 418
Q + C C+NGG C + C CP G+ G+ C CS C NGG
Sbjct: 233 QCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG-----KNCSQECQCHNGG 287
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC C C GY G CQ +G
Sbjct: 288 TCDAATGQ-----CHCSPGYTGERCQDECPVG 314
Score = 49.2 bits (112), Expect = 9e-06
Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
I S C C+N CS +C C G+ G C R S C+L C NG
Sbjct: 450 INCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG-----FGCNLTCQCLNG 504
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
G C + ++ TC C G+ G C++P + G
Sbjct: 505 GAC-----NTLDGTCTCAPGWRGEKCELPCQDG 532
Score = 48.4 bits (110), Expect = 2e-05
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCET--RIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C C+NG C + + C C PG+ G C T + +Y +N S C+N C P
Sbjct: 413 CSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY------GINCSSRCGCKNDAVCSP 466
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
++ +C C G+ G C +
Sbjct: 467 -----VDGSCTCKAGWHGVDCSI 484
Score = 30.7 bits (66), Expect = 3.2
Identities = 9/32 (28%), Positives = 17/32 (53%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSY 334
+ +E C C + C + +C C PG++G +
Sbjct: 536 LNCAERCDCSHADGCHPTTGHCRCLPGWSGLF 567
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 69.7 bits (163), Expect = 6e-12
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 424
+ CQC+NG +C + C CPPGYTG++CE + PP P C PC+NGG C
Sbjct: 193 QRCQCQNGATCDHVTGECRCPPGYTGAFCED------LCPPGKHGPQCEQRCPCQNGGVC 246
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
+ C CP G+ G C P G+
Sbjct: 247 -----HHVTGECSCPSGWMGTVCGQPCPEGR 272
Score = 56.8 bits (131), Expect = 4e-08
Identities = 26/86 (30%), Positives = 43/86 (50%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ +E C C + C + +C C PG++G +C++ A P + PC C+NG
Sbjct: 536 LNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSL-PCY---CKNGA 591
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
+C PD + C+C G+ G +CQ
Sbjct: 592 SCSPD-----DGICECAPGFRGTTCQ 612
Score = 55.2 bits (127), Expect = 1e-07
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPCRNGGT 421
S+ CQC NGG+C + C C PGYTG C E + +Y V C NGG
Sbjct: 278 SQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTY------GVLCAETCQCVNGGK 331
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C ++ C C G+AG C+ L
Sbjct: 332 C-----YHVSGACLCEAGFAGERCEARL 354
Score = 53.2 bits (122), Expect = 5e-07
Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)
Frame = +2
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLM--------S 367
EC G + +E+CQC NGG C S C+C G+ G CE R+ +
Sbjct: 310 ECPVGTYG-VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC 368
Query: 368 PPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQ 496
P N S HP CKP W C+ C G+ G +CQ
Sbjct: 369 PCHLENTHSCHPMSGECACKP---GWSGLYCNETCSPGFYGEACQ 410
Score = 51.2 bits (117), Expect = 2e-06
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 1/120 (0%)
Frame = +2
Query: 140 CIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTNCICPPG 319
C+ + N +N D + CQC+NG C+ + C C G
Sbjct: 113 CVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAG 172
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G CE R N C C+NG TC + C CP GY GA C+
Sbjct: 173 FRGWRCEDRCEQGTYG-----NDCHQRCQCQNGATC-----DHVTGECRCPPGYTGAFCE 222
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 1/92 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 418
Q + C C+NGG C + C CP G+ G+ C CS C NGG
Sbjct: 233 QCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG-----KNCSQECQCHNGG 287
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC C C GY G CQ +G
Sbjct: 288 TCDAATGQ-----CHCSPGYTGERCQDECPVG 314
Score = 49.2 bits (112), Expect = 9e-06
Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 415
I S C C+N CS +C C G+ G C R S C+L C NG
Sbjct: 450 INCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG-----FGCNLTCQCLNG 504
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
G C + ++ TC C G+ G C++P + G
Sbjct: 505 GAC-----NTLDGTCTCAPGWRGEKCELPCQDG 532
Score = 49.2 bits (112), Expect = 9e-06
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKP 430
+C C NG CS C C PG+TG YC R C+L C+NG C
Sbjct: 715 TCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG-----KDCALICQCQNGADC-- 767
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
++ C C G+ G C+ G
Sbjct: 768 ---DHISGQCTCRTGFMGRHCEQKCPSG 792
Score = 48.4 bits (110), Expect = 2e-05
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCET--RIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C C+NG C + + C C PG+ G C T + +Y +N S C+N C P
Sbjct: 413 CSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY------GINCSSRCGCKNDAVCSP 466
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
++ +C C G+ G C +
Sbjct: 467 -----VDGSCTCKAGWHGVDCSI 484
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCE--TRIASYLMSPPPPVNPCS----LHPCRNG 415
+CQC NGG+C+T C C PG+ G CE + +Y ++ + CS HP
Sbjct: 498 TCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCD-CSHADGCHPTTGH 556
Query: 416 GTCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C P W CD C G G +C +P
Sbjct: 557 CRCLP---GWSGVHCDSVCAEGRWGPNCSLP 584
Score = 46.4 bits (105), Expect = 6e-05
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 242 QASESC-QC-ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ S++C QC + G C + C C PG+TG+ C S N + C N
Sbjct: 623 RCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGK----NCAGICTCTNN 678
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
GTC P ++ +C C G+ G+ C P
Sbjct: 679 GTCNP-----IDRSCQCYPGWIGSDCSQP 702
Score = 46.0 bits (104), Expect = 8e-05
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 430
C C N G+C+ +C C PG+ GS C PP P +H C NG C
Sbjct: 673 CTCTNNGTCNPIDRSCQCYPGWIGSDCSQ------PCPPAHWGPNCIHTCNCHNGAFC-- 724
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
S + C C G+ G C LG
Sbjct: 725 ---SAYDGECKCTPGWTGLYCTQRCPLG 749
Score = 46.0 bits (104), Expect = 8e-05
Identities = 25/79 (31%), Positives = 32/79 (40%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CQC+NG C S C C G+ G +CE + S + C N TC
Sbjct: 759 CQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG----YGCRQICDCLNNSTC---- 810
Query: 437 NSWMNHTCDCPLGYAGASC 493
+ TC C G+ GA C
Sbjct: 811 -DHITGTCYCSPGWKGARC 828
Score = 43.2 bits (97), Expect = 6e-04
Identities = 26/79 (32%), Positives = 34/79 (43%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+NG SCS + C C PG+ G+ C+ RI S C + G C
Sbjct: 585 CYCKNGASCSPDDGICECAPGFRGTTCQ-RICSPGFYGHRCSQTCP-QCVHSSGPC---- 638
Query: 437 NSWMNHTCDCPLGYAGASC 493
+ CDC G+ GA C
Sbjct: 639 -HHITGLCDCLPGFTGALC 656
Score = 33.1 bits (72), Expect = 0.61
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Frame = +2
Query: 209 QEC--NTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCE 340
Q+C TY G + C C N +C + C C PG+ G+ C+
Sbjct: 787 QKCPSGTYGYG---CRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 69.3 bits (162), Expect = 8e-12
Identities = 34/80 (42%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S C+CPPG+TGSYC+ VN C PC +GGTC+
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HDVNECDSQPCLHGGTCQDGC 1040
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
S + C CP GY G +CQ
Sbjct: 1041 GS---YRCTCPQGYTGPNCQ 1057
Score = 61.3 bits (142), Expect = 2e-09
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + D+ +S C +GG+C S C CP GYTG C+ V+ C
Sbjct: 1016 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL-----------VHWCD 1064
Query: 395 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 502
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1065 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1097
Score = 60.5 bits (140), Expect = 3e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCR+GGTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRHGGTCQDRDNAYL---CFCLKGTTGPNCEINLD 643
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 907 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 954
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
RNG C +S +TC CP G++G C+
Sbjct: 955 RNGANCTDCVDS---YTCTCPAGFSGIHCE 981
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 59.7 bits (138), Expect = 6e-09
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGG C ES +C+CP G+ G CE +N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGASC-- 884
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+N+ + C C GY+G +C+ ++
Sbjct: 885 -QNTHGGYRCHCQAGYSGRNCETDID 909
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 940 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 988
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 989 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1019
Score = 56.4 bits (130), Expect = 6e-08
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL-ELGQ 517
S++ C CP + G +C+ + E GQ
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQ 184
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +2
Query: 251 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-----------NECASNPCLNQGTC 806
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPL 505
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP-D 433
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 430
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1161
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G +C ++
Sbjct: 1162 DYLGGYSCKCVAGYHGVNCSEEID 1185
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1266 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1314
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C++G +C + C C PGYTGS C I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNINI-----------DECAGNPCHNGGTCE 694
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 53.2 bits (122), Expect = 5e-07
Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC D + + C CP G++G SCQ
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQ 139
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NGG C+ + + + +C CP G+ G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTGWQGQTCEVDI 870
Score = 50.8 bits (116), Expect = 3e-06
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+N +C + CIC PGY G +CE + C+ PC
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN-----------TDECASSPCL 500
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ G C N + C+CP G+ G CQ ++
Sbjct: 501 HNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1202
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N+ + C CP G G C++ ++
Sbjct: 1203 NT---YKCSCPRGTQGVHCEINVD 1223
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 869 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 917
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N+ CDC G+ G C+
Sbjct: 918 NGGSCTDGINTAF---CDCLPGFRGTFCE 943
Score = 47.6 bits (108), Expect = 3e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C S C C PG++G+ C+ N C +PC NGGTCK D S
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTS-- 773
Query: 449 NHTCDCPLGYAGASCQ 496
+ C C G++G +CQ
Sbjct: 774 GYVCTCREGFSGPNCQ 789
Score = 47.2 bits (107), Expect = 3e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 406
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1397
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N GTC+P S + C CP + G C +
Sbjct: 1398 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1427
Score = 46.8 bits (106), Expect = 5e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NGG+C C C PG+TG CE I + C + C+NGG C
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------DDCPGNNCKNGGACVDG 275
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 276 VNT---YNCRCPPEWTGQYC 292
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 424
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 2e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C C GY G C++
Sbjct: 472 GEFQ---CICMPGYEGVHCEV 489
Score = 44.0 bits (99), Expect = 3e-04
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Frame = +2
Query: 203 NIQECNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPP 376
N+ +CN S S +C N G+C + +C CPPG+ G CE
Sbjct: 1221 NVDDCNPPVD---PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------G 1266
Query: 377 PVNPCSLHPCRNGGT--CKPDRNSWMNHTCDCPLGYAGASCQ 496
VN C +PC GT C N + H C+C G+ G C+
Sbjct: 1267 DVNECLSNPCDARGTQNCVQRVNDF--H-CECRAGHTGRRCE 1305
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 38.3 bits (85), Expect = 0.016
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C +GG+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ GTC + + C C GY G+ C + ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNINID 680
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 69.3 bits (162), Expect = 8e-12
Identities = 34/80 (42%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S C+CPPG+TGSYC+ VN C PC +GGTC+
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HDVNECDSQPCLHGGTCQDGC 1040
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
S + C CP GY G +CQ
Sbjct: 1041 GS---YRCTCPQGYTGPNCQ 1057
Score = 61.3 bits (142), Expect = 2e-09
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + D+ +S C +GG+C S C CP GYTG C+ V+ C
Sbjct: 1016 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL-----------VHWCD 1064
Query: 395 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 502
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1065 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1097
Score = 60.5 bits (140), Expect = 3e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCR+GGTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRHGGTCQDRDNAYL---CFCLKGTTGPNCEINLD 643
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 907 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 954
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
RNG C +S +TC CP G++G C+
Sbjct: 955 RNGANCTDCVDS---YTCTCPAGFSGIHCE 981
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 59.7 bits (138), Expect = 6e-09
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGG C ES +C+CP G+ G CE +N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGASC-- 884
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+N+ + C C GY+G +C+ ++
Sbjct: 885 -QNTHGGYRCHCQAGYSGRNCETDID 909
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 940 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 988
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 989 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1019
Score = 56.4 bits (130), Expect = 6e-08
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL-ELGQ 517
S++ C CP + G +C+ + E GQ
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQ 184
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +2
Query: 251 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-----------NECASNPCLNQGTC 806
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPL 505
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP-D 433
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 430
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1161
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G +C ++
Sbjct: 1162 DYLGGYSCKCVAGYHGVNCSEEID 1185
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1266 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1314
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C++G +C + C C PGYTGS C I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNINI-----------DECAGNPCHNGGTCE 694
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 53.2 bits (122), Expect = 5e-07
Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC D + + C CP G++G SCQ
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQ 139
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NGG C+ + + + +C CP G+ G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTGWQGQTCEVDI 870
Score = 50.8 bits (116), Expect = 3e-06
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+N +C + CIC PGY G +CE + C+ PC
Sbjct: 452 DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN-----------TDECASSPCL 500
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ G C N + C+CP G+ G CQ ++
Sbjct: 501 HNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1202
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N+ + C CP G G C++ ++
Sbjct: 1203 NT---YKCSCPRGTQGVHCEINVD 1223
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 869 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 917
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N+ CDC G+ G C+
Sbjct: 918 NGGSCTDGINTAF---CDCLPGFRGTFCE 943
Score = 47.6 bits (108), Expect = 3e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C S C C PG++G+ C+ N C +PC NGGTCK D S
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTS-- 773
Query: 449 NHTCDCPLGYAGASCQ 496
+ C C G++G +CQ
Sbjct: 774 GYVCTCREGFSGPNCQ 789
Score = 47.2 bits (107), Expect = 3e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 406
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1397
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N GTC+P S + C CP + G C +
Sbjct: 1398 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1427
Score = 46.8 bits (106), Expect = 5e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NGG+C C C PG+TG CE I + C + C+NGG C
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------DDCPGNNCKNGGACVDG 275
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 276 VNT---YNCRCPPEWTGQYC 292
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 424
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 2e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C C GY G C++
Sbjct: 472 GEFQ---CICMPGYEGVHCEV 489
Score = 44.0 bits (99), Expect = 3e-04
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Frame = +2
Query: 203 NIQECNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPP 376
N+ +CN S S +C N G+C + +C CPPG+ G CE
Sbjct: 1221 NVDDCNPPVD---PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------G 1266
Query: 377 PVNPCSLHPCRNGGT--CKPDRNSWMNHTCDCPLGYAGASCQ 496
VN C +PC GT C N + H C+C G+ G C+
Sbjct: 1267 DVNECLSNPCDARGTQNCVQRVNDF--H-CECRAGHTGRRCE 1305
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 38.3 bits (85), Expect = 0.016
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C +GG+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ GTC + + C C GY G+ C + ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNINID 680
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 69.3 bits (162), Expect = 8e-12
Identities = 34/80 (42%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S C+CPPG+TGSYC+ VN C PC +GGTC+
Sbjct: 504 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HDVNECDSQPCLHGGTCQDGC 552
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
S + C CP GY G +CQ
Sbjct: 553 GS---YRCTCPQGYTGPNCQ 569
Score = 61.3 bits (142), Expect = 2e-09
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + D+ +S C +GG+C S C CP GYTG C+ V+ C
Sbjct: 528 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL-----------VHWCD 576
Query: 395 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 502
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 577 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 609
Score = 60.5 bits (140), Expect = 3e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 73 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 121
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCR+GGTC+ N+++ C C G G +C++ L+
Sbjct: 122 QPCRHGGTCQDRDNAYL---CFCLKGTTGPNCEINLD 155
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 419 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 466
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
RNG C +S +TC CP G++G C+
Sbjct: 467 RNGANCTDCVDS---YTCTCPAGFSGIHCE 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C NGG C ES +C+CP G+ G CE +N C L PCR+G +C
Sbjct: 350 CRNGGECRQSEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGASC-- 396
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+N+ + C C GY+G +C+ ++
Sbjct: 397 -QNTHGGYRCHCQAGYSGRNCETDID 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 452 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 500
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 501 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 531
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +2
Query: 251 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 270 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-----------NECASNPCLNQGTC 318
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPL 505
D + C+C L Y GA+C++ L
Sbjct: 319 IDD---VAGYKCNCLLPYTGATCEVVL 342
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 628 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 673
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G +C ++
Sbjct: 674 DYLGGYSCKCVAGYHGVNCSEEID 697
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 778 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 826
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 827 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 858
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C++G +C + C C PGYTGS C I + C+ +PC NGGTC+
Sbjct: 159 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNINI-----------DECAGNPCHNGGTCE 206
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
N + TC CP GY +C
Sbjct: 207 DGINGF---TCRCPEGYHDPTC 225
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 303 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 351
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NGG C+ + + + +C CP G+ G +C++ +
Sbjct: 352 NGGECRQSED-YESFSCVCPTGWQGQTCEVDI 382
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 666 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 714
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N+ + C CP G G C++ ++
Sbjct: 715 NT---YKCSCPRGTQGVHCEINVD 735
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 381 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 429
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N+ CDC G+ G C+
Sbjct: 430 NGGSCTDGINTAF---CDCLPGFRGTFCE 455
Score = 47.6 bits (108), Expect = 3e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 8 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 56
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ +TC C GY G C++ ++
Sbjct: 57 DGPNT---YTCVCTEGYTGTHCEVDID 80
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C S C C PG++G+ C+ N C +PC NGGTCK D S
Sbjct: 240 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTS-- 285
Query: 449 NHTCDCPLGYAGASCQ 496
+ C C G++G +CQ
Sbjct: 286 GYVCTCREGFSGPNCQ 301
Score = 47.2 bits (107), Expect = 3e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 406
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 860 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 909
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N GTC+P S + C CP + G C +
Sbjct: 910 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 939
Score = 46.8 bits (106), Expect = 5e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 40 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 87
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G+CK + TC C GY G C+
Sbjct: 88 HYGSCK---DGVATFTCLCRPGYTGHHCE 113
Score = 44.0 bits (99), Expect = 3e-04
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 4/102 (3%)
Frame = +2
Query: 203 NIQECNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPP 376
N+ +CN S S +C N G+C + +C CPPG+ G CE
Sbjct: 733 NVDDCNPPVD---PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------G 778
Query: 377 PVNPCSLHPCRNGGT--CKPDRNSWMNHTCDCPLGYAGASCQ 496
VN C +PC GT C N + H C+C G+ G C+
Sbjct: 779 DVNECLSNPCDARGTQNCVQRVNDF--H-CECRAGHTGRRCE 817
Score = 38.3 bits (85), Expect = 0.016
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C +GG+C C C G TG CE + + C+ PC
Sbjct: 115 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 162
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ GTC + + C C GY G+ C + ++
Sbjct: 163 DSGTCLDKID---GYECACEPGYTGSMCNINID 192
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/40 (32%), Positives = 20/40 (50%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C+ PC + G C N + C+CP G+ G CQ ++
Sbjct: 6 CASSPCLHNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 42
>U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein.
Length = 263
Score = 68.5 bits (160), Expect = 1e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 24 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLND 71
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 72 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 100
Score = 57.2 bits (132), Expect = 3e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 59 EINECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 107
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + S C CP G+ GA C +P
Sbjct: 108 NKGTCVQKKAS---PQCLCPSGWVGAYCDVP 135
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+N G+C + S C+CP G+ G+YC+ S ++ H C++ G C
Sbjct: 106 CKNKGTCVQKKASPQCLCPSGWVGAYCDVPNVSCDIAASRR-GVLVEHLCQHSGVC---I 161
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N+ H C CP+GY G+ C+ L+
Sbjct: 162 NAGNTHYCQCPVGYTGSYCEEQLD 185
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 154 CQHSGVCINAGNTHYCQCPVGYTGSYCEEQL-----------DECASNPCQHGATCS--- 199
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 200 DFIGGYRCECVPGYQGVNCEYEVD 223
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 178 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 226
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 496
PC+NGGTC +NH C CP G G C+
Sbjct: 227 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 257
Score = 44.0 bits (99), Expect = 3e-04
Identities = 24/67 (35%), Positives = 32/67 (47%)
Frame = +2
Query: 293 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 472
S C C G+ G +CE I N C+ C NGGTC NS+ +C CP+
Sbjct: 4 SYTCKCQAGFDGVHCENNI-----------NECTESSCFNGGTCVDGINSF---SCLCPV 49
Query: 473 GYAGASC 493
G+ G+ C
Sbjct: 50 GFTGSFC 56
Score = 34.7 bits (76), Expect = 0.20
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRI 349
++ ++ C+NGG+C C CPPG G CE I
Sbjct: 221 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI 260
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 68.1 bits (159), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 60.1 bits (139), Expect = 5e-09
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C+NGGSC + +C+C PG+TG +T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQT-----------DMNECLSEPCK 959
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC NS +TC C G+ G C+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCE 985
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 54.4 bits (125), Expect = 2e-07
Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 68 FVGGVDDSTVV-VNPNAGVSGGFSGCIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDI 241
F G DS V P+ V+GG D N + S NI +C +
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----- 267
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+C+NGG C + NC CPP +TG +C + L+ P + C+NG
Sbjct: 268 ------RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP---------NACQNG 312
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASC 493
GTC +RN + C C G++G C
Sbjct: 313 GTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 9e-06
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 8e-05
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N++ +C C G+ G Q
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKYQ 947
Score = 45.6 bits (103), Expect = 1e-04
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQMPL 505
PC+NGGTC +NH C CP G G + +
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGMKSSLSI 1226
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC+N TC + TC C G+ G C++ + QS
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQS 500
Score = 44.4 bits (100), Expect = 2e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPL 505
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 6e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +2
Query: 257 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 403
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 449 NHTCDCPLGYAGASCQMPLE 508
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +2
Query: 260 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 440 SWMNHTCDCPLGYAGASCQM 499
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.003
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 479 AGASC 493
SC
Sbjct: 713 HHPSC 717
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV 382
Q CN DI S C G +C CICP G C ++ V
Sbjct: 677 QRCNI----DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------V 721
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N C +PC + G C + C C G+ G +C++
Sbjct: 722 NECLSNPCIH-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 0.80
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 68.1 bits (159), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC NS +TC C G+ G C+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCE 985
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 54.4 bits (125), Expect = 2e-07
Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 68 FVGGVDDSTVV-VNPNAGVSGGFSGCIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDI 241
F G DS V P+ V+GG D N + S NI +C +
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----- 267
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+C+NGG C + NC CPP +TG +C + L+ P + C+NG
Sbjct: 268 ------RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP---------NACQNG 312
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASC 493
GTC +RN + C C G++G C
Sbjct: 313 GTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 4e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 9e-06
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 496
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 373
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 374 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC+N TC + TC C G+ G C++ + QS
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQS 500
Score = 44.4 bits (100), Expect = 2e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPL 505
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 6e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +2
Query: 257 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 403
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 449 NHTCDCPLGYAGASCQMPLE 508
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +2
Query: 260 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 440 SWMNHTCDCPLGYAGASCQM 499
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.003
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 479 AGASC 493
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +2
Query: 254 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 412
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 413 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 505
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.26
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 430
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV 382
Q CN DI S C G +C CICP G C ++ V
Sbjct: 677 QRCNI----DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------V 721
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N C +PC + G C + C C G+ G +C++
Sbjct: 722 NECLSNPCIH-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 0.80
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 68.1 bits (159), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC NS +TC C G+ G C+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCE 985
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 54.4 bits (125), Expect = 2e-07
Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 68 FVGGVDDSTVV-VNPNAGVSGGFSGCIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDI 241
F G DS V P+ V+GG D N + S NI +C +
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----- 267
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+C+NGG C + NC CPP +TG +C + L+ P + C+NG
Sbjct: 268 ------RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP---------NACQNG 312
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASC 493
GTC +RN + C C G++G C
Sbjct: 313 GTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 4e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 9e-06
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 496
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 373
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 374 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC+N TC + TC C G+ G C++ + QS
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQS 500
Score = 44.4 bits (100), Expect = 2e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPL 505
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 6e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +2
Query: 257 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 403
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 449 NHTCDCPLGYAGASCQMPLE 508
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +2
Query: 260 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 440 SWMNHTCDCPLGYAGASCQM 499
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.003
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 479 AGASC 493
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +2
Query: 254 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 412
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 413 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 505
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.26
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 430
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV 382
Q CN DI S C G +C CICP G C ++ V
Sbjct: 677 QRCNI----DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------V 721
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N C +PC + G C + C C G+ G +C++
Sbjct: 722 NECLSNPCIH-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 0.80
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 68.1 bits (159), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC NS +TC C G+ G C+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCE 985
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 54.4 bits (125), Expect = 2e-07
Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 68 FVGGVDDSTVV-VNPNAGVSGGFSGCIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDI 241
F G DS V P+ V+GG D N + S NI +C +
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----- 267
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+C+NGG C + NC CPP +TG +C + L+ P + C+NG
Sbjct: 268 ------RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP---------NACQNG 312
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASC 493
GTC +RN + C C G++G C
Sbjct: 313 GTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 4e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 9e-06
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 496
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 373
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 374 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC+N TC + TC C G+ G C++ + QS
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQS 500
Score = 44.4 bits (100), Expect = 2e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPL 505
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 6e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +2
Query: 257 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 403
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 449 NHTCDCPLGYAGASCQMPLE 508
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +2
Query: 260 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 440 SWMNHTCDCPLGYAGASCQM 499
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.003
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 479 AGASC 493
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +2
Query: 254 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 412
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 413 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 505
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.26
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 430
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV 382
Q CN DI S C G +C CICP G C ++ V
Sbjct: 677 QRCNI----DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------V 721
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N C +PC + G C + C C G+ G +C++
Sbjct: 722 NECLSNPCIH-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 0.80
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 68.1 bits (159), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC NS +TC C G+ G C+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCE 985
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 54.4 bits (125), Expect = 2e-07
Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 68 FVGGVDDSTVV-VNPNAGVSGGFSGCIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDI 241
F G DS V P+ V+GG D N + S NI +C +
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----- 267
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+C+NGG C + NC CPP +TG +C + L+ P + C+NG
Sbjct: 268 ------RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP---------NACQNG 312
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASC 493
GTC +RN + C C G++G C
Sbjct: 313 GTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 51.6 bits (118), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 50.4 bits (115), Expect = 4e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 9e-06
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 496
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 373
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 374 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC+N TC + TC C G+ G C++ + QS
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQS 500
Score = 44.4 bits (100), Expect = 2e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPL 505
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 199 LNLPGSYQCQCLQGFTGQYC 218
Score = 43.2 bits (97), Expect = 6e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +2
Query: 257 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 403
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 449 NHTCDCPLGYAGASCQMPLE 508
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +2
Query: 260 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 440 SWMNHTCDCPLGYAGASCQM 499
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.003
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 479 AGASC 493
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +2
Query: 254 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 412
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 413 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 505
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.26
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 430
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV 382
Q CN DI S C G +C CICP G C ++ V
Sbjct: 677 QRCNI----DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------V 721
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N C +PC + G C + C C G+ G +C++
Sbjct: 722 NECLSNPCIH-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 0.80
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 68.1 bits (159), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +2
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC NS +TC C G+ G C+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCE 985
Score = 57.6 bits (133), Expect = 2e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 8e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 54.4 bits (125), Expect = 2e-07
Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Frame = +2
Query: 68 FVGGVDDSTVV-VNPNAGVSGGFSGCIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDI 241
F G DS V P+ V+GG D N + S NI +C +
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----- 267
Query: 242 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+C+NGG C + NC CPP +TG +C + L+ P + C+NG
Sbjct: 268 ------RCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP---------NACQNG 312
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASC 493
GTC +RN + C C G++G C
Sbjct: 313 GTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 4e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 9e-06
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 263 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLE 508
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 395 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 496
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 373
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 374 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
PC+N TC + TC C G+ G C++ + QS
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQS 500
Score = 44.4 bits (100), Expect = 2e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPL 505
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 6e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +2
Query: 257 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 403
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +2
Query: 275 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 449 NHTCDCPLGYAGASCQMPLE 508
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.001
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +2
Query: 260 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 440 SWMNHTCDCPLGYAGASCQM 499
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.003
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.009
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 479 AGASC 493
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +2
Query: 254 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 412
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 413 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 505
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.26
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 430
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV 382
Q CN DI S C G +C CICP G C ++ V
Sbjct: 677 QRCNI----DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------V 721
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N C +PC + G C + C C G+ G +C++
Sbjct: 722 NECLSNPCIH-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 0.80
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.
Length = 1097
Score = 68.1 bits (159), Expect = 2e-11
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 7/133 (5%)
Frame = +2
Query: 119 VSGGFSGCIKDVVLNSNAVDINSSIKS-SNIQECNTYDRGDIQASESCQ---CENGGSCS 286
V GF GC+ V+LN+N + + + S + + G + ++C+ C++GGSC+
Sbjct: 486 VLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACKRSPCQHGGSCT 545
Query: 287 ---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHT 457
+ C C +TG CE+ I + C +PCRNGG+C P N+++
Sbjct: 546 GLPSGGYQCTCLSQFTGRNCESEITA-----------CFPNPCRNGGSCDPIGNTFI--- 591
Query: 458 CDCPLGYAGASCQ 496
C+C G G +C+
Sbjct: 592 CNCKAGLTGVTCE 604
Score = 46.0 bits (104), Expect = 8e-05
Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSC C C G TG CE I N C C NGG+C
Sbjct: 577 CRNGGSCDPIGNTFICNCKAGLTGVTCEEDI-----------NECEREECENGGSCV--- 622
Query: 437 NSWMNHTCDCPLGYAGASC 493
N + + C+C GY G C
Sbjct: 623 NVFGSFLCNCTPGYVGQYC 641
Score = 42.3 bits (95), Expect = 0.001
Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETR 346
DI E +CENGGSC S C C PGY G YC R
Sbjct: 606 DINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLR 644
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 67.3 bits (157), Expect = 3e-11
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Frame = +2
Query: 38 AESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSS-IKSSNIQE 214
++ L T +++GGV+ S V ++P +S F GC+ +V +N +D+ S + S I +
Sbjct: 4043 SQGLNLHTLLYLGGVEPS-VPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQ 4101
Query: 215 CNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 385
C YD + C++G +C C+C G+ G CE N
Sbjct: 4102 C--YDSSPCERQP---CQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------EN 4145
Query: 386 PCSL-HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC L PC +GGTC+ R C C G++G CQ
Sbjct: 4146 PCQLREPCLHGGTCQGTR-------CLCLPGFSGPRCQ 4176
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 3788 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3845
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 3846 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 3887
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 3888 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 33.9 bits (74), Expect = 0.35
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +2
Query: 266 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 439
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1114 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1173
Query: 440 S---WMNHT----CD-CPLGYAG 484
+ +HT C+ C GY G
Sbjct: 1174 ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 31.5 bits (68), Expect = 1.9
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 826 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 869
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1628 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 31.1 bits (67), Expect = 2.4
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 475
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDP----VYGHCLNCQHN 786
Query: 476 YAGASC 493
G C
Sbjct: 787 TEGPQC 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 2/72 (2%)
Frame = +2
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRNSWMNHTCD 463
E C CPPGY G C+ Y + + C L C + C P+ +
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGA----CSQ 1581
Query: 464 CPLGYAGASCQM 499
C AG C++
Sbjct: 1582 CQHNAAGEFCEL 1593
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 protein.
Length = 4391
Score = 67.3 bits (157), Expect = 3e-11
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Frame = +2
Query: 38 AESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSS-IKSSNIQE 214
++ L T +++GGV+ S V ++P +S F GC+ +V +N +D+ S + S I +
Sbjct: 4043 SQGLNLHTLLYLGGVEPS-VPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQ 4101
Query: 215 CNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 385
C YD + C++G +C C+C G+ G CE N
Sbjct: 4102 C--YDSSPCERQP---CQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------EN 4145
Query: 386 PCSL-HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC L PC +GGTC+ R C C G++G CQ
Sbjct: 4146 PCQLREPCLHGGTCQGTR-------CLCLPGFSGPRCQ 4176
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 3788 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3845
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 3846 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 3887
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 3888 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 33.9 bits (74), Expect = 0.35
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +2
Query: 266 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 439
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1114 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1173
Query: 440 S---WMNHT----CD-CPLGYAG 484
+ +HT C+ C GY G
Sbjct: 1174 ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 31.5 bits (68), Expect = 1.9
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 826 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 869
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1628 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 30.7 bits (66), Expect = 3.2
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 475
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDP----VYGHCLNCQHN 786
Query: 476 YAGASC 493
G C
Sbjct: 787 TEGPQC 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 2/72 (2%)
Frame = +2
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRNSWMNHTCD 463
E C CPPGY G C+ Y + + C L C + C P+ +
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGA----CSQ 1581
Query: 464 CPLGYAGASCQM 499
C AG C++
Sbjct: 1582 CQHNAAGEFCEL 1593
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 protein.
Length = 4391
Score = 67.3 bits (157), Expect = 3e-11
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Frame = +2
Query: 38 AESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSS-IKSSNIQE 214
++ L T +++GGV+ S V ++P +S F GC+ +V +N +D+ S + S I +
Sbjct: 4043 SQGLNLHTLLYLGGVEPS-VPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQ 4101
Query: 215 CNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 385
C YD + C++G +C C+C G+ G CE N
Sbjct: 4102 C--YDSSPCERQP---CQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------EN 4145
Query: 386 PCSL-HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC L PC +GGTC+ R C C G++G CQ
Sbjct: 4146 PCQLREPCLHGGTCQGTR-------CLCLPGFSGPRCQ 4176
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 3788 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3845
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 3846 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 3887
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 3888 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 33.9 bits (74), Expect = 0.35
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +2
Query: 266 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 439
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1114 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1173
Query: 440 S---WMNHT----CD-CPLGYAG 484
+ +HT C+ C GY G
Sbjct: 1174 ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 31.5 bits (68), Expect = 1.9
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 826 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 869
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1628 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 30.7 bits (66), Expect = 3.2
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 475
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDP----VYGHCLNCQHN 786
Query: 476 YAGASC 493
G C
Sbjct: 787 TEGPQC 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 2/72 (2%)
Frame = +2
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRNSWMNHTCD 463
E C CPPGY G C+ Y + + C L C + C P+ +
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGA----CSQ 1581
Query: 464 CPLGYAGASCQM 499
C AG C++
Sbjct: 1582 CQHNAAGEFCEL 1593
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 67.3 bits (157), Expect = 3e-11
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Frame = +2
Query: 38 AESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSS-IKSSNIQE 214
++ L T +++GGV+ S V ++P +S F GC+ +V +N +D+ S + S I +
Sbjct: 4022 SQGLNLHTLLYLGGVEPS-VPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQ 4080
Query: 215 CNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 385
C YD + C++G +C C+C G+ G CE N
Sbjct: 4081 C--YDSSPCERQP---CQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------EN 4124
Query: 386 PCSL-HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC L PC +GGTC+ R C C G++G CQ
Sbjct: 4125 PCQLREPCLHGGTCQGTR-------CLCLPGFSGPRCQ 4155
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 3767 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3824
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 3825 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 3866
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 3867 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 3901
Score = 33.9 bits (74), Expect = 0.35
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +2
Query: 266 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 439
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1093 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1152
Query: 440 S---WMNHT----CD-CPLGYAG 484
+ +HT C+ C GY G
Sbjct: 1153 ACQGCQHHTEGPRCEQCQPGYYG 1175
Score = 31.5 bits (68), Expect = 1.9
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 805 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 848
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1607 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1647
Score = 31.1 bits (67), Expect = 2.4
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 475
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 710 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDP----VYGHCLNCQHN 765
Query: 476 YAGASC 493
G C
Sbjct: 766 TEGPQC 771
Score = 29.5 bits (63), Expect = 7.5
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 2/72 (2%)
Frame = +2
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRNSWMNHTCD 463
E C CPPGY G C+ Y + + C L C + C P+ +
Sbjct: 1505 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGA----CSQ 1560
Query: 464 CPLGYAGASCQM 499
C AG C++
Sbjct: 1561 CQHNAAGEFCEL 1572
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 67.3 bits (157), Expect = 3e-11
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Frame = +2
Query: 38 AESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSS-IKSSNIQE 214
++ L T +++GGV+ S V ++P +S F GC+ +V +N +D+ S + S I +
Sbjct: 1983 SQGLNLHTLLYLGGVEPS-VPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQ 2041
Query: 215 CNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 385
C YD + C++G +C C+C G+ G CE N
Sbjct: 2042 C--YDSSPCERQP---CQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------EN 2085
Query: 386 PCSL-HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC L PC +GGTC+ R C C G++G CQ
Sbjct: 2086 PCQLREPCLHGGTCQGTR-------CLCLPGFSGPRCQ 2116
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 1728 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 1785
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 1786 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 1827
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 1828 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 1862
>BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein.
Length = 740
Score = 66.9 bits (156), Expect = 4e-11
Identities = 48/157 (30%), Positives = 76/157 (48%), Gaps = 6/157 (3%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKS-SNIQECNT 223
LR E + +GG+ ++++ ++ VS GF GC+ VV+N A+D+ + K+ + + E
Sbjct: 276 LRPERHLLLGGL----ILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQA 331
Query: 224 YDRGDIQASESCQ--CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNP 388
+ + + Q C NGG CS T C CPP ++G +CE +
Sbjct: 332 LTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN----------- 380
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C+ PC GGTC S +C+CP Y G C+M
Sbjct: 381 CTFAPCLEGGTC---ILSPKGASCNCPHPYTGDRCEM 414
>AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 protein.
Length = 4349
Score = 66.9 bits (156), Expect = 4e-11
Identities = 48/157 (30%), Positives = 76/157 (48%), Gaps = 6/157 (3%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKS-SNIQECNT 223
LR E + +GG+ ++++ ++ VS GF GC+ VV+N A+D+ + K+ + + E
Sbjct: 3885 LRPERHLLLGGL----ILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQA 3940
Query: 224 YDRGDIQASESCQ--CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNP 388
+ + + Q C NGG CS T C CPP ++G +CE +
Sbjct: 3941 LTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN----------- 3989
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C+ PC GGTC S +C+CP Y G C+M
Sbjct: 3990 CTFAPCLEGGTC---ILSPKGASCNCPHPYTGDRCEM 4023
>AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant 1
protein.
Length = 573
Score = 66.9 bits (156), Expect = 4e-11
Identities = 48/157 (30%), Positives = 76/157 (48%), Gaps = 6/157 (3%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKS-SNIQECNT 223
LR E + +GG+ ++++ ++ VS GF GC+ VV+N A+D+ + K+ + + E
Sbjct: 109 LRPERHLLLGGL----ILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQA 164
Query: 224 YDRGDIQASESCQ--CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNP 388
+ + + Q C NGG CS T C CPP ++G +CE +
Sbjct: 165 LTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN----------- 213
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C+ PC GGTC S +C+CP Y G C+M
Sbjct: 214 CTFAPCLEGGTC---ILSPKGASCNCPHPYTGDRCEM 247
>AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein.
Length = 573
Score = 66.9 bits (156), Expect = 4e-11
Identities = 48/157 (30%), Positives = 76/157 (48%), Gaps = 6/157 (3%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKS-SNIQECNT 223
LR E + +GG+ ++++ ++ VS GF GC+ VV+N A+D+ + K+ + + E
Sbjct: 109 LRPERHLLLGGL----ILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQA 164
Query: 224 YDRGDIQASESCQ--CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNP 388
+ + + Q C NGG CS T C CPP ++G +CE +
Sbjct: 165 LTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN----------- 213
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C+ PC GGTC S +C+CP Y G C+M
Sbjct: 214 CTFAPCLEGGTC---ILSPKGASCNCPHPYTGDRCEM 247
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 3790 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3847
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 3848 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 3889
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 3890 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 3924
Score = 65.7 bits (153), Expect = 9e-11
Identities = 47/158 (29%), Positives = 72/158 (45%), Gaps = 5/158 (3%)
Frame = +2
Query: 38 AESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSS-IKSSNIQE 214
++ L T +++GGV+ S V ++P +S F GC+ +V +N +D+ S + S I +
Sbjct: 4045 SQGLNLHTLLYLGGVEPS-VPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQ 4103
Query: 215 CNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 385
C YD + C++G +C C+C G G CE N
Sbjct: 4104 C--YDSSPCERQP---CQHGATCMPAGEYEFQCLCRDGIKGDLCEHE-----------EN 4147
Query: 386 PCSLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC L PC +GGTC+ R C C G++G CQ
Sbjct: 4148 PCQLREPCLHGGTCQGTR-------CLCLPGFSGPRCQ 4178
Score = 33.9 bits (74), Expect = 0.35
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +2
Query: 266 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 439
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1116 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1175
Query: 440 S---WMNHT----CD-CPLGYAG 484
+ +HT C+ C GY G
Sbjct: 1176 ACQGCQHHTEGPRCEQCQPGYYG 1198
Score = 31.5 bits (68), Expect = 1.9
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 475
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 733 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDP----VYGHCLNCQHN 788
Query: 476 YAGASCQ 496
G C+
Sbjct: 789 TEGPQCK 795
Score = 31.5 bits (68), Expect = 1.9
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 828 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 871
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1630 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1670
Score = 29.5 bits (63), Expect = 7.5
Identities = 19/72 (26%), Positives = 27/72 (37%), Gaps = 2/72 (2%)
Frame = +2
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRNSWMNHTCD 463
E C CPPGY G C+ Y + + C L C + C P+ +
Sbjct: 1528 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGA----CSQ 1583
Query: 464 CPLGYAGASCQM 499
C AG C++
Sbjct: 1584 CQHNAAGEFCEL 1595
>BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein.
Length = 351
Score = 66.1 bits (154), Expect = 7e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +2
Query: 41 ESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINS-SIKSSNIQEC 217
+ L +++GG D + P AG+S GF GC++++ + + + ++ + I C
Sbjct: 23 QGLDLNEELYLGGYPDYGAI--PKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 80
Query: 218 NTY-DRGDIQASESCQCENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVN 385
T DR C+NGG C +ES++ C+CP G+TGS CE A +
Sbjct: 81 PTCRDR---------PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------- 122
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C TC +R +TC C LG +G C+
Sbjct: 123 -CHPEACGPDATC-VNRPDGRGYTCRCHLGRSGLRCE 157
>U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein
Del-1 protein.
Length = 480
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRI-ASYLMSPPPPVNP 388
+ +GDI + CENGG C + S +C CP G+T C + + + P P
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGP 77
Query: 389 CSLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 496
C+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 78 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 117
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +2
Query: 263 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 83 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 131
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
G C + N++C+CP + G +CQ
Sbjct: 132 GIC---TDLVANYSCECPGEFMGRNCQ 155
Score = 36.7 bits (81), Expect = 0.049
Identities = 14/41 (34%), Positives = 22/41 (53%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C +PC NGG C P + +C+CP G+ +C +E+
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEV 65
>BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and
discoidin I-like domains 3 protein.
Length = 480
Score = 64.5 bits (150), Expect = 2e-10
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRI-ASYLMSPPPPVNP 388
+ +GDI + CENGG C + S +C CP G+T C + + + P P
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGP 77
Query: 389 CSLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 496
C+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 78 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 117
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +2
Query: 263 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 83 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 131
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
G C + N++C+CP + G +CQ
Sbjct: 132 GIC---TDLVANYSCECPGEFMGRNCQ 155
Score = 36.7 bits (81), Expect = 0.049
Identities = 14/41 (34%), Positives = 22/41 (53%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C +PC NGG C P + +C+CP G+ +C +E+
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEV 65
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQS 974
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKP 1173
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 897 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 945
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 946 AQPSGYL---CQCAPGYDGQNCSKELDACQS 973
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 445 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 490
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 491 DLLATFHCLCPPGLEGQLCEV 511
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 696 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 744
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 745 PSPGGYY---CTCPPSHTGPQCQ 764
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 281 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPP-------H-CRNGGTC- 331
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 332 --QNSAGSFHCVCVSGWGGTSCEENLD 356
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1004 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1052
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1053 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1083
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 400 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 451
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 452 -LNTPGSFNCLCPPGYTGSRCE 472
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 772 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 821
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 822 ---DSPQGPRCLCPTGYTGGSCQTLMDL 846
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 204 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 252
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 253 EKDSTF-HLCLCPPGFIGPGCEV 274
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 930 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 978
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 979 HGTCTPKPGGF--H-CACPPGFVGLRCE 1003
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 650 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 695
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 696 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 725
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 242 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVN----------PDN-CVSHQCQNGGTC 290
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 291 QDGLDT---YTCLCPETWTGWDC 310
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 728 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 776
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 777 NGGTCV---NRPGTFSCLCAMGFQGPRCE 802
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 550 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 598
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 599 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 627
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1045 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1093
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1094 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1127
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 126 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 172
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 173 --TYPQIQCHCPPGFEGHACE 191
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 164 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 211
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 212 NTLGSFQCLCPVGQEGPRCEL 232
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 518 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 566
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 567 DQPGAF--H-CKCLPGFEGPRCQTEVD 590
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 814 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 862
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 863 PSF--H-CLCLQGWTGPLCNLPL 882
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 845 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 902
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 903 GGLCV---DSGPSYFCHCPPGFQGSLCQ 927
Score = 41.1 bits (92), Expect = 0.002
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
D + +A C NGG+C S S +C+C G+ G+ CE + + C
Sbjct: 313 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAA 361
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G TC DR + +C CP G G C +
Sbjct: 362 TCAPGSTC-IDRVG--SFSCLCPPGRTGLLCHL 391
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 483 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 531
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 532 NGFQ---CICLPGFSGTRCEEDID 552
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 23 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 72
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 73 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 118
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 597 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 656
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 657 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 691
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 363 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 410
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 411 LTGST-LCLCQPGYSGPTCHQDLD 433
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 73 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 122
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 123 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 155
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1095 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1146
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1147 ETTGLGGPGFRCSCPHSSPGPRCQKP 1172
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQS 974
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKP 1173
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQS 974
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKP 1173
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQS 974
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 50.0 bits (114), Expect = 5e-06
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP Y G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTVYTGGSCQTLMDL 847
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 39.1 bits (87), Expect = 0.009
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP YTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTVYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKP 1173
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQS 974
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 50.0 bits (114), Expect = 5e-06
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP Y G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTVYTGGSCQTLMDL 847
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 39.1 bits (87), Expect = 0.009
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP YTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTVYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKP 1173
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQS 974
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKP 1173
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 64.1 bits (149), Expect = 3e-10
Identities = 35/91 (38%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 900 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 948
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+ ++ C C GY G +C L+ QS
Sbjct: 949 AQPSGYL---CQCAPGYDGQNCSKELDACQS 976
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 448 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 493
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 494 DLLATFHCLCPPGLEGQLCEV 514
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 699 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 747
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 748 PSPGGYY---CTCPPSHTGPQCQ 767
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 284 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPP-------H-CRNGGTC- 334
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 335 --QNSAGSFHCVCVSGWGGTSCEENLD 359
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1007 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1055
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1056 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1086
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 403 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 454
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 455 -LNTPGSFNCLCPPGYTGSRCE 475
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 775 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 824
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 825 ---DSPQGPRCLCPTGYTGGSCQTLMDL 849
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 207 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 255
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 256 EKDSTF-HLCLCPPGFIGPDCEV 277
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 933 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 981
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 982 HGTCTPKPGGF--H-CACPPGFVGLRCE 1006
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 653 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 698
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 699 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 728
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 245 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 293
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 294 QDGLDT---YTCLCPETWTGWDC 313
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 731 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 779
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 780 NGGTCV---NRPGTFSCLCAMGFQGPRCE 805
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 553 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 601
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 602 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 630
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1048 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1096
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 1097 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1130
Score = 46.8 bits (106), Expect = 5e-05
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Frame = +2
Query: 221 TYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
T +R Q + C C G C +++ C C PG+TG C+ R
Sbjct: 112 TGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------ 159
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 160 DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 194
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 167 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 214
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 215 NTLGSFQCLCPVGQEGPRCEL 235
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 521 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 569
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 570 DQPGAF--H-CKCLPGFEGPRCQTEVD 593
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 817 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 865
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 866 PSF--H-CLCLQGWTGPLCNLPL 885
Score = 42.7 bits (96), Expect = 8e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 848 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 905
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 906 GGLCV---DSGPSYFCHCPPGFQGSLCQ 930
Score = 41.1 bits (92), Expect = 0.002
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
D + +A C NGG+C S S +C+C G+ G+ CE + + C
Sbjct: 316 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAA 364
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G TC DR + +C CP G G C +
Sbjct: 365 TCAPGSTC-IDRVG--SFSCLCPPGRTGLLCHL 394
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 486 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 534
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 535 NGFQ---CICLPGFSGTRCEEDID 555
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 26 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 75
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 76 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE 121
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 600 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 659
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 660 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 694
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 366 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 413
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 414 LTGST-LCLCQPGYSGPTCHQDLD 436
Score = 35.1 bits (77), Expect = 0.15
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 76 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE----------DPCP 125
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 126 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 158
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1098 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1149
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 1150 ETTGLGGPGFRCSCPHSSPGPRCQKP 1175
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 63.7 bits (148), Expect = 4e-10
Identities = 37/98 (37%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Frame = +2
Query: 236 DIQASESCQ---CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I +SC C NGG+C C CPPG++G YCE ++P +PC
Sbjct: 231 EIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRYCE-------IAP----SPCFRS 279
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
PC NGGTC+ DR++ + C C GY G CQ ++ G
Sbjct: 280 PCVNGGTCE-DRDT--DFFCHCQAGYMGRRCQAEVDCG 314
Score = 59.3 bits (137), Expect = 8e-09
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C +GGSC C+C GY G++CE + C HPCR
Sbjct: 368 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER-----------DECRAHPCR 416
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C RN + C CP G+ G C+ ++
Sbjct: 417 NGGSC---RNLPGAYVCRCPAGFVGVHCETEVD 446
Score = 57.6 bits (133), Expect = 2e-08
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSC +S C CP G+ G +CE + +L CS PCRNGGTCK
Sbjct: 165 CFNGGSCDAHDDSYTCECPRGFHGKHCE-KARPHL---------CSSGPCRNGGTCK--- 211
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ + C CP + G C++
Sbjct: 212 EAGGEYHCSCPYRFTGRHCEI 232
Score = 55.2 bits (127), Expect = 1e-07
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A +S C++GG C + C+CP G+ G +CET +PC PC
Sbjct: 444 EVDACDSSPCQHGGRCESGGGAYLCVCPEGFFGYHCET-----------VSDPCFSSPCG 492
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C S H+C C +GY G C L
Sbjct: 493 GRGYCLASNGS---HSCTCKVGYTGEDCAKEL 521
Score = 52.0 bits (119), Expect = 1e-06
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSC + C CP G+ G +CET V+ C PC++GG C+
Sbjct: 415 CRNGGSCRNLPGAYVCRCPAGFVGVHCETE-----------VDACDSSPCQHGGRCESGG 463
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+++ C CP G+ G C+
Sbjct: 464 GAYL---CVCPEGFFGYHCE 480
Score = 48.8 bits (111), Expect = 1e-05
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
C T D A S C NGG+C + + C CP G+ G C R+ +
Sbjct: 37 CETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP----------DD 86
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C CRNGG C + C CPLG+ G C+ +
Sbjct: 87 CE---CRNGGRCLGANTT----LCQCPLGFFGLLCEFEI 118
Score = 48.4 bits (110), Expect = 2e-05
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 29/111 (26%)
Frame = +2
Query: 251 ESCQCENGGSC-STESTNCICPPGY---------------------TGSYCETRIASYLM 364
+ C+C NGG C +T C CP G+ G YC SYL
Sbjct: 85 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 144
Query: 365 SPPPPVN-------PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N PC+ PC NGG+C +S +TC+CP G+ G C+
Sbjct: 145 VCHTDHNASHSLPSPCNSDPCFNGGSCDAHDDS---YTCECPRGFHGKHCE 192
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 906 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 939
Score = 34.3 bits (75), Expect = 0.26
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 911 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 966
Score = 31.9 bits (69), Expect = 1.4
Identities = 15/39 (38%), Positives = 21/39 (53%)
Frame = +2
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
V+ CS PC NGG+C + N+TC C + G C+
Sbjct: 3 VDDCSPDPCLNGGSCV---DLVGNYTCLCAEPFKGLRCE 38
>BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog
(Drosophila) protein.
Length = 383
Score = 62.9 bits (146), Expect = 7e-10
Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
D+ + + C+NGG C + +C+C PG+ G CE + PC
Sbjct: 89 DKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AGPCEQ 137
Query: 398 --HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCRNGG C+ D+ +N TC C +G+ GA C++ ++
Sbjct: 138 AGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 176
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 183 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 230
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP GY G +C++ L
Sbjct: 231 VH--DFDCLCPSGYGGKTCELVL 251
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 190
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N + +C CP G+AG C + L+
Sbjct: 191 DGINRF---SCLCPEGFAGRFCTINLD 214
Score = 33.9 bits (74), Expect = 0.35
Identities = 21/78 (26%), Positives = 36/78 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++G +C + CIC G+ G +C+ ++ + + PC+NGG C D
Sbjct: 66 CQHG-TCH-QPWQCICHSGWAGKFCDK--DEHICT--------TQSPCQNGGQCMYDGGG 113
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C C G+ G C+
Sbjct: 114 --EYHCVCLPGFHGRDCE 129
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 257
>BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF
repeat containing protein.
Length = 737
Score = 62.9 bits (146), Expect = 7e-10
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 600
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G+ GA+C++ L+
Sbjct: 601 N---GYNCHCPHGWVGANCEIHLQ 621
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Frame = +2
Query: 251 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 399
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
PCRNG TC +S TC CP GY G++C+ ++L
Sbjct: 400 PCRNGATC---ISSLSGFTCQCPEGYFGSACEEKVDL 433
Score = 55.2 bits (127), Expect = 1e-07
Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 8/119 (6%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQ-ECNTYDRGDIQAS--ESC---QCENGGSC--STESTNCICPP 316
N++ +D N SN C G++ S + C C NG +C S C CP
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 420
Query: 317 GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
GY GS CE + V+ C+ PC+N GTC D ++ TC+C G+ G +C
Sbjct: 421 GYFGSACEEK-----------VDLCASSPCQNNGTCYVD---GVHFTCNCSPGFTGPTC 465
Score = 45.2 bits (102), Expect = 1e-04
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 188 SIKSSNIQECNTYDRGDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIAS 355
+++ + + + +T G+ A++ +C G C+T E+T +C C Y G++CE
Sbjct: 295 ALRLTLVVKVSTCVPGESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE----- 348
Query: 356 YLMSPPPPVNPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ C PC+N +C ++ N TC C GY G CQ ++
Sbjct: 349 -------EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Score = 43.6 bits (98), Expect = 4e-04
Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++ D+ AS CQ N G+C + + C C PG+TG C I + C+L
Sbjct: 429 EKVDLCASSPCQ--NNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALS 475
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC + GTC R+ ++ C C GY G C+
Sbjct: 476 PCAH-GTC---RSVGTSYKCLCDPGYHGLYCE 503
Score = 43.2 bits (97), Expect = 6e-04
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +2
Query: 275 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 525
Query: 449 NHTCDCPLGYAGASCQM 499
+ C C Y G C++
Sbjct: 526 GYECVCLAEYKGTHCEL 542
Score = 42.3 bits (95), Expect = 0.001
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 9/54 (16%)
Frame = +2
Query: 365 SPPPPVNPCSLHPCRNGGTC----KPDRN-----SWMNHTCDCPLGYAGASCQM 499
+P PC+ PCRNGG C +PD ++C CP G +GA+CQ+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 559
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
D +N TC C G+ G C + +
Sbjct: 560 SD---GLNGTCICAPGFTGEECDIDI 582
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C CP G +G+ C+ +PC+ +PC +G +S + C C GY
Sbjct: 79 SCTCPAGISGANCQL-----------VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 479 AGASCQMPL 505
G +C+ L
Sbjct: 128 EGPNCEQAL 136
Score = 31.1 bits (67), Expect = 2.4
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Frame = +2
Query: 245 ASESCQ---CENGGSCSTESTNCICPPGYTGSYCETRIAS 355
AS C C + S S++ CIC GY G CE + S
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
>BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein.
Length = 454
Score = 62.9 bits (146), Expect = 7e-10
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 269 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 317
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G+ GA+C++ L+
Sbjct: 318 N---GYNCHCPHGWVGANCEIHLQ 338
Score = 59.7 bits (138), Expect = 6e-09
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Frame = +2
Query: 251 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 68 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 116
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PCRNG TC +S TC CP GY G++C+
Sbjct: 117 PCRNGATC---ISSLSGFTCQCPEGYFGSACE 145
Score = 59.3 bits (137), Expect = 8e-09
Identities = 39/119 (32%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQ-ECNTYDRGDIQAS--ESC---QCENGGSC--STESTNCICPP 316
N++ +D N SN C G++ S + C C NG +C S C CP
Sbjct: 78 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 137
Query: 317 GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
GY GS CE + V+PC+ PC+N GTC D ++ TC+C G+ G +C
Sbjct: 138 GYFGSACEEK-----------VDPCASSPCQNNGTCYVD---GVHFTCNCSPGFTGPTC 182
Score = 45.2 bits (102), Expect = 1e-04
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 188 SIKSSNIQECNTYDRGDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIAS 355
+++ + + + +T G+ A++ +C G C+T E+T +C C Y G++CE A
Sbjct: 12 ALRLTLVVKVSTCVPGESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA- 69
Query: 356 YLMSPPPPVNPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N +C ++ N TC C GY G CQ ++
Sbjct: 70 -----------CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 111
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 153 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 199
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
R+ ++ C C GY G C+
Sbjct: 200 --RSVGTSYKCLCDPGYHGLYCE 220
Score = 43.2 bits (97), Expect = 6e-04
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +2
Query: 275 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 197 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 242
Query: 449 NHTCDCPLGYAGASCQM 499
+ C C Y G C++
Sbjct: 243 GYECVCLAEYKGTHCEL 259
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 228 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 276
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
D +N TC C G+ G C + +
Sbjct: 277 SD---GLNGTCICAPGFTGEECDIDI 299
>AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein.
Length = 737
Score = 62.9 bits (146), Expect = 7e-10
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 600
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G+ GA+C++ L+
Sbjct: 601 N---GYNCHCPHGWVGANCEIHLQ 621
Score = 59.7 bits (138), Expect = 6e-09
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Frame = +2
Query: 251 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 399
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PCRNG TC +S TC CP GY G++C+
Sbjct: 400 PCRNGATC---ISSLSGFTCQCPEGYFGSACE 428
Score = 59.3 bits (137), Expect = 8e-09
Identities = 39/119 (32%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQ-ECNTYDRGDIQAS--ESC---QCENGGSC--STESTNCICPP 316
N++ +D N SN C G++ S + C C NG +C S C CP
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 420
Query: 317 GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
GY GS CE + V+PC+ PC+N GTC D ++ TC+C G+ G +C
Sbjct: 421 GYFGSACEEK-----------VDPCASSPCQNNGTCYVD---GVHFTCNCSPGFTGPTC 465
Score = 45.2 bits (102), Expect = 1e-04
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 188 SIKSSNIQECNTYDRGDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIAS 355
+++ + + + +T G+ A++ +C G C+T E+T +C C Y G++CE A
Sbjct: 295 ALRLTLVVKVSTCVPGESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA- 352
Query: 356 YLMSPPPPVNPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N +C ++ N TC C GY G CQ ++
Sbjct: 353 -----------CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 482
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
R+ ++ C C GY G C+
Sbjct: 483 --RSVGTSYKCLCDPGYHGLYCE 503
Score = 43.2 bits (97), Expect = 6e-04
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +2
Query: 275 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 525
Query: 449 NHTCDCPLGYAGASCQM 499
+ C C Y G C++
Sbjct: 526 GYECVCLAEYKGTHCEL 542
Score = 42.3 bits (95), Expect = 0.001
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 9/54 (16%)
Frame = +2
Query: 365 SPPPPVNPCSLHPCRNGGTC----KPDRN-----SWMNHTCDCPLGYAGASCQM 499
+P PC+ PCRNGG C +PD ++C CP G +GA+CQ+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 559
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
D +N TC C G+ G C + +
Sbjct: 560 SD---GLNGTCICAPGFTGEECDIDI 582
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C CP G +G+ C+ +PC+ +PC +G +S + C C GY
Sbjct: 79 SCTCPAGISGANCQL-----------VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 479 AGASCQMPL 505
G +C+ L
Sbjct: 128 EGPNCEQAL 136
Score = 31.1 bits (67), Expect = 2.4
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Frame = +2
Query: 245 ASESCQ---CENGGSCSTESTNCICPPGYTGSYCETRIAS 355
AS C C + S S++ CIC GY G CE + S
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
>AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein.
Length = 383
Score = 62.9 bits (146), Expect = 7e-10
Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
D+ + + C+NGG C + +C+C PG+ G CE + PC
Sbjct: 89 DKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AGPCEQ 137
Query: 398 --HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCRNGG C+ D+ +N TC C +G+ GA C++ ++
Sbjct: 138 AGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 176
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 183 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 230
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP GY G +C++ L
Sbjct: 231 VH--DFDCLCPSGYGGKTCELVL 251
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 190
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N + +C CP G+AG C + L+
Sbjct: 191 DGINRF---SCLCPEGFAGRFCTINLD 214
Score = 33.9 bits (74), Expect = 0.35
Identities = 21/78 (26%), Positives = 36/78 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++G +C + CIC G+ G +C+ ++ + + PC+NGG C D
Sbjct: 66 CQHG-TCH-QPWQCICHSGWAGKFCDK--DEHICT--------TQSPCQNGGQCMYDGGG 113
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C C G+ G C+
Sbjct: 114 --EYHCVCLPGFHGRDCE 129
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 257
>AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 383
Score = 62.9 bits (146), Expect = 7e-10
Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
D+ + + C+NGG C + +C+C PG+ G CE + PC
Sbjct: 89 DKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AGPCEQ 137
Query: 398 --HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PCRNGG C+ D+ +N TC C +G+ GA C++ ++
Sbjct: 138 AGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 176
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 183 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 230
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP GY G +C++ L
Sbjct: 231 VH--DFDCLCPSGYGGKTCELVL 251
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 190
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N + +C CP G+AG C + L+
Sbjct: 191 DGINRF---SCLCPEGFAGRFCTINLD 214
Score = 33.9 bits (74), Expect = 0.35
Identities = 21/78 (26%), Positives = 36/78 (46%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++G +C + CIC G+ G +C+ ++ + + PC+NGG C D
Sbjct: 66 CQHG-TCH-QPWQCICHSGWAGKFCDK--DEHICT--------TQSPCQNGGQCMYDGGG 113
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C C G+ G C+
Sbjct: 114 --EYHCVCLPGFHGRDCE 129
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 257
>AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein
protein.
Length = 252
Score = 62.9 bits (146), Expect = 7e-10
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 67 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 115
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G+ GA+C++ L+
Sbjct: 116 N---GYNCHCPHGWVGANCEIHLQ 136
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 26 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 74
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
D +N TC C G+ G C + +
Sbjct: 75 SD---GLNGTCICAPGFTGEECDIDI 97
Score = 41.1 bits (92), Expect = 0.002
Identities = 23/69 (33%), Positives = 28/69 (40%)
Frame = +2
Query: 293 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 472
S C+C PGY G YCE N C PC N TC+ N + C C
Sbjct: 3 SYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN---GYECVCLA 48
Query: 473 GYAGASCQM 499
Y G C++
Sbjct: 49 EYKGTHCEL 57
>AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF
repeat-containing transmembrane protein protein.
Length = 737
Score = 62.9 bits (146), Expect = 7e-10
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 600
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C CP G+ GA+C++ L+
Sbjct: 601 N---GYNCHCPHGWVGANCEIHLQ 621
Score = 59.7 bits (138), Expect = 6e-09
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Frame = +2
Query: 251 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 399
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PCRNG TC +S TC CP GY G++C+
Sbjct: 400 PCRNGATC---ISSLSGFTCQCPEGYFGSACE 428
Score = 59.3 bits (137), Expect = 8e-09
Identities = 39/119 (32%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQ-ECNTYDRGDIQAS--ESC---QCENGGSC--STESTNCICPP 316
N++ +D N SN C G++ S + C C NG +C S C CP
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 420
Query: 317 GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
GY GS CE + V+PC+ PC+N GTC D ++ TC+C G+ G +C
Sbjct: 421 GYFGSACEEK-----------VDPCASSPCQNNGTCYVD---GVHFTCNCSPGFTGPTC 465
Score = 45.2 bits (102), Expect = 1e-04
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 188 SIKSSNIQECNTYDRGDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIAS 355
+++ + + + +T G+ A++ +C G C+T E+T +C C Y G++CE A
Sbjct: 295 ALRLTLVVKVSTCVPGESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA- 352
Query: 356 YLMSPPPPVNPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N +C ++ N TC C GY G CQ ++
Sbjct: 353 -----------CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 482
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
R+ ++ C C GY G C+
Sbjct: 483 --RSVGTSYKCLCDPGYHGLYCE 503
Score = 43.2 bits (97), Expect = 6e-04
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +2
Query: 275 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 525
Query: 449 NHTCDCPLGYAGASCQM 499
+ C C Y G C++
Sbjct: 526 GYECVCLAEYKGTHCEL 542
Score = 42.3 bits (95), Expect = 0.001
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 9/54 (16%)
Frame = +2
Query: 365 SPPPPVNPCSLHPCRNGGTC----KPDRN-----SWMNHTCDCPLGYAGASCQM 499
+P PC+ PCRNGG C +PD ++C CP G +GA+CQ+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Score = 42.3 bits (95), Expect = 0.001
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 559
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
D +N TC C G+ G C + +
Sbjct: 560 SD---GLNGTCICAPGFTGEECDIDI 582
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C CP G +G+ C+ +PC+ +PC +G +S + C C GY
Sbjct: 79 SCTCPAGISGANCQL-----------VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 479 AGASCQMPL 505
G +C+ L
Sbjct: 128 EGPNCEQAL 136
Score = 31.1 bits (67), Expect = 2.4
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Frame = +2
Query: 245 ASESCQ---CENGGSCSTESTNCICPPGYTGSYCETRIAS 355
AS C C + S S++ CIC GY G CE + S
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
>AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 377
Score = 62.5 bits (145), Expect = 9e-10
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTCK 427
C+NGG C + +C+C PG+ G CE + PC PCRNGG C+
Sbjct: 95 CQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AGPCEQAGSPCRNGGQCQ 143
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
D+ +N TC C +G+ GA C++ ++
Sbjct: 144 DDQGFALNFTCRCLVGFVGARCEVNVD 170
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 177 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 224
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP GY G +C++ L
Sbjct: 225 VH--DFDCLCPSGYGGKTCELVL 245
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 136 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 184
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N + +C CP G+AG C + L+
Sbjct: 185 DGINRF---SCLCPEGFAGRFCTINLD 208
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 15/96 (15%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP--CSLH--------- 400
S C+ C +C C PG+ G +CE + P C H
Sbjct: 30 SSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWADEHIC 89
Query: 401 ----PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PC+NGG C D + C C G+ G C+
Sbjct: 90 TTQSPCQNGGQCMYDGGG--EYHCVCLPGFHGRDCE 123
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 215 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 251
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 62.1 bits (144), Expect = 1e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--RYVCECARGYGGPNCQFLL 520
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I + C+NGGSC+ S +C CPPG+ G CE + C+ PC N
Sbjct: 329 IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT-----------CADGPCFN 377
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
GG C + ++C CP+GY+G +C+ ++
Sbjct: 378 GGRCSDSPDG--GYSCRCPVGYSGFNCEKKID 407
Score = 58.0 bits (134), Expect = 2e-08
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
NS ++C CP G+ G C++
Sbjct: 347 ENS---YSCTCPPGFYGKICEL 365
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 46.4 bits (105), Expect = 6e-05
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG CS +C CP GY+G CE +I + CS PC NG C
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-----------DYCSSSPCSNGAKCVDL 423
Query: 434 RNSWMNHTCDCPLGYAGASC 493
++++ C C G++G C
Sbjct: 424 GDAYL---CRCQAGFSGRHC 440
Score = 44.0 bits (99), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATCTNTGQG--S 311
Query: 452 HTCDCPLGYAGASCQMPLE 508
+TC C GY GA+C++ ++
Sbjct: 312 YTCSCRPGYTGATCELGID 330
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 62.1 bits (144), Expect = 1e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--RYVCECARGYGGPNCQFLL 520
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I + C+NGGSC+ S +C CPPG+ G CE + C+ PC N
Sbjct: 329 IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT-----------CADGPCFN 377
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
GG C + ++C CP+GY+G +C+ ++
Sbjct: 378 GGRCSDSPDG--GYSCRCPVGYSGFNCEKKID 407
Score = 58.0 bits (134), Expect = 2e-08
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
NS ++C CP G+ G C++
Sbjct: 347 ENS---YSCTCPPGFYGKICEL 365
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 46.4 bits (105), Expect = 6e-05
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG CS +C CP GY+G CE +I + CS PC NG C
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-----------DYCSSSPCSNGAKCVDL 423
Query: 434 RNSWMNHTCDCPLGYAGASC 493
++++ C C G++G C
Sbjct: 424 GDAYL---CRCQAGFSGRHC 440
Score = 44.0 bits (99), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATCTNTGQG--S 311
Query: 452 HTCDCPLGYAGASCQMPLE 508
+TC C GY GA+C++ ++
Sbjct: 312 YTCSCRPGYTGATCELGID 330
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 62.1 bits (144), Expect = 1e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--GYVCECARGYGGPNCQFLL 520
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I + C+NGGSC+ S +C CPPG+ G CE + C+ PC N
Sbjct: 329 IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT-----------CADGPCFN 377
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
GG C + ++C CP+GY+G +C+ ++
Sbjct: 378 GGRCSDSPDG--GYSCRCPVGYSGFNCEKKID 407
Score = 58.0 bits (134), Expect = 2e-08
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
NS ++C CP G+ G C++
Sbjct: 347 ENS---YSCTCPPGFYGKICEL 365
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 46.4 bits (105), Expect = 6e-05
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG CS +C CP GY+G CE +I + CS PC NG C
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-----------DYCSSSPCSNGAKCVDL 423
Query: 434 RNSWMNHTCDCPLGYAGASC 493
++++ C C G++G C
Sbjct: 424 GDAYL---CRCQAGFSGRHC 440
Score = 44.0 bits (99), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATCTNTGQG--S 311
Query: 452 HTCDCPLGYAGASCQMPLE 508
+TC C GY GA+C++ ++
Sbjct: 312 YTCSCRPGYTGATCELGID 330
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 62.1 bits (144), Expect = 1e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--GYVCECARGYGGPNCQFLL 520
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I + C+NGGSC+ S +C CPPG+ G CE + C+ PC N
Sbjct: 329 IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT-----------CADGPCFN 377
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
GG C + ++C CP+GY+G +C+ ++
Sbjct: 378 GGRCSDSPDG--GYSCRCPVGYSGFNCEKKID 407
Score = 58.0 bits (134), Expect = 2e-08
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
NS ++C CP G+ G C++
Sbjct: 347 ENS---YSCTCPPGFYGKICEL 365
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 46.4 bits (105), Expect = 6e-05
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG CS +C CP GY+G CE +I + CS PC NG C
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-----------DYCSSSPCSNGAKCVDL 423
Query: 434 RNSWMNHTCDCPLGYAGASC 493
++++ C C G++G C
Sbjct: 424 GDAYL---CRCQAGFSGRHC 440
Score = 44.0 bits (99), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATCTNTGQG--S 311
Query: 452 HTCDCPLGYAGASCQMPLE 508
+TC C GY GA+C++ ++
Sbjct: 312 YTCSCRPGYTGATCELGID 330
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 61.7 bits (143), Expect = 2e-09
Identities = 36/98 (36%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Frame = +2
Query: 236 DIQASESCQ---CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I +SC C NGG+C C CPPG++G +CE ++P +PC
Sbjct: 485 EIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCE-------IAP----SPCFRS 533
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
PC NGGTC+ DR++ + C C GY G CQ ++ G
Sbjct: 534 PCVNGGTCE-DRDT--DFFCHCQAGYMGRRCQAEVDCG 568
Score = 59.7 bits (138), Expect = 6e-09
Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C+NGG+C+ S C CP G+ G CET +PC C+
Sbjct: 180 DVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCET-----------AQSPCDTKECQ 228
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+GG C+ + S C C GY GA+C+M ++
Sbjct: 229 HGGQCQVENGS---AVCVCQAGYTGAACEMDVD 258
Score = 59.3 bits (137), Expect = 8e-09
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C +GGSC C+C GY G++CE + C HPCR
Sbjct: 622 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER-----------DECRAHPCR 670
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG+C RN + C CP G+ G C+ ++
Sbjct: 671 NGGSC---RNLPGAYVCRCPAGFVGVHCETEVD 700
Score = 58.4 bits (135), Expect = 1e-08
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 251 ESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
+S C NGGSC +S C CP G+ G +CE + +L CS PCRNGGTC
Sbjct: 415 DSDPCFNGGSCDAHDDSYTCECPRGFHGKHCE-KARPHL---------CSSGPCRNGGTC 464
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
K + + C CP + G C++
Sbjct: 465 K---EAGGEYHCSCPYRFTGRHCEI 486
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Frame = +2
Query: 263 CENGGSCSTE------STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG C + S C C G+TG C VN C+ PC+NGGTC
Sbjct: 147 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHL-----------DVNECASQPCQNGGTC 195
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
NS+ C CP G+ G +C+
Sbjct: 196 THGINSF---RCQCPAGFGGPTCE 216
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A +S C++GG C + C+CP + G +CET +PC PC
Sbjct: 698 EVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCET-----------VSDPCFSSPCG 746
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C S H+C C +GY G C L
Sbjct: 747 GRGYCLASNGS---HSCTCKVGYTGEDCAKEL 775
Score = 52.4 bits (120), Expect = 9e-07
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C++GG C E S C+C GYTG+ CE V+ CS PC NGG+C
Sbjct: 226 ECQHGGQCQVENGSAVCVCQAGYTGAACEM-----------DVDDCSPDPCLNGGSCV-- 272
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ N+TC C + G C+
Sbjct: 273 -DLVGNYTCLCAEPFKGLRCE 292
Score = 49.6 bits (113), Expect = 7e-06
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSC + C CP G+ G +CET V+ C PC++GG C+
Sbjct: 669 CRNGGSCRNLPGAYVCRCPAGFVGVHCETE-----------VDACDSSPCQHGGRCESGG 717
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+++ C CP + G C+
Sbjct: 718 GAYL---CVCPESFFGYHCE 734
Score = 48.8 bits (111), Expect = 1e-05
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
C T D A S C NGG+C + + C CP G+ G C R+ +
Sbjct: 291 CETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP----------DD 340
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C CRNGG C + C CPLG+ G C+ +
Sbjct: 341 CE---CRNGGRCLGANTT----LCQCPLGFFGLLCEFEI 372
Score = 48.0 bits (109), Expect = 2e-05
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 29/111 (26%)
Frame = +2
Query: 251 ESCQCENGGSC-STESTNCICPPGY---------------------TGSYCETRIASYLM 364
+ C+C NGG C +T C CP G+ G YC SYL
Sbjct: 339 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 398
Query: 365 SPPPPVN-------PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N PC PC NGG+C +S +TC+CP G+ G C+
Sbjct: 399 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDS---YTCECPRGFHGKHCE 446
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 1180 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 1213
Score = 34.3 bits (75), Expect = 0.26
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 1185 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 1240
Score = 33.1 bits (72), Expect = 0.61
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Frame = +2
Query: 392 SLHPCRNGGTCKPD-RNSWMNHTCDCPLGYAGASCQM 499
+L PC NGG C D ++TC C G+ G C +
Sbjct: 143 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHL 179
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 61.7 bits (143), Expect = 2e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + N CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSL-----------NSCSSGPCENGGTC 979
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLLSV 1168
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LNSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 47.2 bits (107), Expect = 3e-05
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1278 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1337
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1338 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1378
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC H C +G C P ++++C C GY+GA C
Sbjct: 1379 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALC 1412
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 36.7 bits (81), Expect = 0.049
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C PC+N GTC D + C CP GY G C++ L
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSL 965
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 3.2
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +2
Query: 260 QCENGG--SCSTESTNCICPPGYTGSYCE 340
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 214
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + + C C G+ G +C++ ++
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVD 238
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1103
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+M C+C GY G +C+
Sbjct: 1104 GGYM---CECLPGYNGDNCE 1120
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 431 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 479
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG CK N + +C CP G++G++CQ+ ++
Sbjct: 480 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVD 509
Score = 57.6 bits (133), Expect = 2e-08
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 784
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C+ C CP G+ G CQ ++
Sbjct: 785 RCESAPGQL--PVCSCPQGWQGPRCQQDVD 812
Score = 55.6 bits (128), Expect = 1e-07
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 427
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 291
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ H+C C G+ G SC ++
Sbjct: 292 --FNTLGGHSCVCVNGWTGESCSQNID 316
Score = 54.4 bits (125), Expect = 2e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1067
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
H C CP G G+ C+ ++
Sbjct: 1068 ---HYCVCPEGRTGSHCEQEVD 1086
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 512
Query: 395 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 493
PCRNG C +PD + C C G+ G C
Sbjct: 513 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 542
Score = 52.8 bits (121), Expect = 7e-07
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 421
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 125 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 173
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMP 502
C N+ + C CP GY G C+ P
Sbjct: 174 C---LNTPGSFRCQCPAGYTGPLCENP 197
Score = 52.0 bits (119), Expect = 1e-06
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLHPCRNGGTCKP 430
QC G C + C CPPG +G C S+ SPP N C+ PC +GG+C+P
Sbjct: 1297 QCPVGVPCQQTPRGPRCACPPGLSGPSCR----SFPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 431 DRNSWMNHTCDCPLGYAGASCQMP 502
+ C C G+ G C+ P
Sbjct: 1353 APLAPF-FRCACAQGWTGPRCEAP 1375
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ C NGG+C S +C+C PGYTG++C+ +PC PC
Sbjct: 924 DLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADPCLSRPCL 972
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+GG C + C C + G CQ
Sbjct: 973 HGGVCSAAHPGF---RCTCLESFTGPQCQ 998
Score = 50.4 bits (115), Expect = 4e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +2
Query: 263 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 96
Query: 434 -RNSWMNHTCDCPLGYAGASCQMP 502
+C CP G+ G C +P
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLP 120
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 899 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 946
Query: 449 NHTCDCPLGYAGASCQ 496
+C C GY GA CQ
Sbjct: 947 --SCLCRPGYTGAHCQ 960
Score = 49.2 bits (112), Expect = 9e-06
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +2
Query: 293 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 472
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 565 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 610
Query: 473 GYAGASCQMPLE 508
G G +C++ ++
Sbjct: 611 GTTGVNCEVNID 622
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 254
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 255 VNT---YNCQCPPEWTGQFC 271
Score = 48.0 bits (109), Expect = 2e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 449
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
TC C G+ G C++ ++ QS
Sbjct: 450 IG--QFTCICMAGFTGTYCEVDIDECQS 475
Score = 48.0 bits (109), Expect = 2e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 718 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 765
Query: 482 GASCQM 499
G C++
Sbjct: 766 GRQCEL 771
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1177
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ GTC + C CP GY G C+
Sbjct: 1178 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1203
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C NGGSC S +C C PG+ G C V+ C +PC
Sbjct: 849 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC- 896
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GTC S+ TC CP GY G C+ L
Sbjct: 897 GPGTCTDHVASF---TCTCPPGYGGFHCEQDL 925
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1138
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ + C CP G G C++
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEI 1159
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 406
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 402
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G C + S++ C C GY G C+
Sbjct: 403 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 429
Score = 44.0 bits (99), Expect = 3e-04
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G C+ S +C C GYTG C+ I N C +PC NGG+C+
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-----------NDCDPNPCLNGGSCQDGV 868
Query: 437 NSWMNHTCDCPLGYAGASC 493
S+ +C C G+AG C
Sbjct: 869 GSF---SCSCLPGFAGPRC 884
Score = 41.1 bits (92), Expect = 0.002
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 475
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1232 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
Query: 476 YAGASCQ 496
+ G C+
Sbjct: 1281 FWGPRCE 1287
Score = 40.7 bits (91), Expect = 0.003
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 140
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
C CP GY G SC+ ++
Sbjct: 141 --RFLCSCPPGYQGRSCRSDVD 160
Score = 40.7 bits (91), Expect = 0.003
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 358
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC C D N C CP G+ G +C ++
Sbjct: 359 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD 393
Score = 40.7 bits (91), Expect = 0.003
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 642 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 687
Query: 479 AGASCQMP 502
C P
Sbjct: 688 LPPLCLPP 695
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 1017
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
C CP G++G C +
Sbjct: 1018 ---TGAYCLCPPGWSGRLCDI 1035
Score = 39.9 bits (89), Expect = 0.005
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 705
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+ G C + C C G++G C L
Sbjct: 706 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 733
Score = 37.1 bits (82), Expect = 0.037
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG C + C CP G TG CE I + C+ +PC
Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI-----------DDCASNPC-T 630
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C+ N + C C G+ G C + +
Sbjct: 631 FGVCRDGIN---RYDCVCQPGFTGPLCNVEI 658
Score = 37.1 bits (82), Expect = 0.037
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1223
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
++ C C G++G CQ L
Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVL 1247
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
CE+GG C + C CP G+ G C+ + + P P P H G C
Sbjct: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPAPCGP---H-----GICTNL 829
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
S+ +C C GY G SC +
Sbjct: 830 AGSF---SCTCHGGYTGPSCDQDI 850
Score = 33.5 bits (73), Expect = 0.46
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Frame = +2
Query: 359 LMSPPPPVNPC-SLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM 499
L P PC PC NGG C P R + C CP G+ G CQ+
Sbjct: 33 LAGPGAAAPPCLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQL 78
Score = 33.1 bits (72), Expect = 0.61
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 8/86 (9%)
Frame = +2
Query: 263 CENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C +GGSC C C G+TG CE A+ +S P + R C
Sbjct: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1403
Query: 431 DRNS----WMNHTCDCPLGYAGASCQ 496
+ NS W C +G C+
Sbjct: 1404 ECNSPGCGWDGGDCSLSVGDPWRQCE 1429
>AL050329-2|CAB99359.1| 399|Homo sapiens protein ( Human DNA
sequence from clone RP1-22I17 on chromosome 6q11.1-12
Contains the 3' end of the PHF3 gene for PHD finger
protein 3. ).
Length = 399
Score = 61.3 bits (142), Expect = 2e-09
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 6/157 (3%)
Frame = +2
Query: 44 SLRFETPMFVGGVDDSTVVVNPNA--GVSGGFSGCIKDVVLNSNAVDIN--SSIKSSNIQ 211
SL T ++GGV S +VNP A GF GCI+ V++N+ + + + SN+
Sbjct: 69 SLDTNTDFYIGGVS-SLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVG 127
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVN 385
+C D A C NGG C+ T +C C P + G+ C ++
Sbjct: 128 DC------DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS----------- 170
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C + C + C PD++ +++C C LG+ G C+
Sbjct: 171 -CLNNLCLHQSLCIPDQS--FSYSCLCTLGWVGRYCE 204
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I + C+NGGSC+ S +C CPPG+ G CE + C+ PC N
Sbjct: 329 IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT-----------CADGPCFN 377
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
GG C + ++C CP+GY+G +C+ ++
Sbjct: 378 GGRCSDSPDG--GYSCRCPVGYSGFNCEKKID 407
Score = 59.7 bits (138), Expect = 6e-09
Identities = 31/86 (36%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ ++ C+C Y G +CQ L
Sbjct: 498 QRGHGYV---CECARSYGGPNCQFLL 520
Score = 58.0 bits (134), Expect = 2e-08
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
NS ++C CP G+ G C++
Sbjct: 347 ENS---YSCTCPPGFYGKICEL 365
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 46.4 bits (105), Expect = 6e-05
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG CS +C CP GY+G CE +I + CS PC NG C
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-----------DYCSSSPCSNGAKCVDL 423
Query: 434 RNSWMNHTCDCPLGYAGASC 493
++++ C C G++G C
Sbjct: 424 GDAYL---CRCQAGFSGRHC 440
Score = 44.0 bits (99), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 451
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATCTNTGQG--S 311
Query: 452 HTCDCPLGYAGASCQMPLE 508
+TC C GY GA+C++ ++
Sbjct: 312 YTCSCRPGYTGATCELGID 330
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 214
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + + C C G+ G +C++ ++
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVD 238
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1103
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+M C+C GY G +C+
Sbjct: 1104 GGYM---CECLPGYNGDNCE 1120
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 431 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 479
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG CK N + +C CP G++G++CQ+ ++
Sbjct: 480 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVD 509
Score = 57.6 bits (133), Expect = 2e-08
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 784
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C+ C CP G+ G CQ ++
Sbjct: 785 RCESAPGQL--PVCSCPQGWQGPRCQQDVD 812
Score = 55.6 bits (128), Expect = 1e-07
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 427
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 291
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ H+C C G+ G SC ++
Sbjct: 292 --FNTLGGHSCVCVNGWTGESCSQNID 316
Score = 54.4 bits (125), Expect = 2e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1067
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
H C CP G G+ C+ ++
Sbjct: 1068 ---HYCVCPEGRTGSHCEQEVD 1086
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 512
Query: 395 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 493
PCRNG C +PD + C C G+ G C
Sbjct: 513 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 542
Score = 52.8 bits (121), Expect = 7e-07
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 421
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 125 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 173
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMP 502
C N+ + C CP GY G C+ P
Sbjct: 174 C---LNTPGSFRCQCPAGYTGPLCENP 197
Score = 52.0 bits (119), Expect = 1e-06
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLHPCRNGGTCKP 430
QC G C + C CPPG +G C S+ SPP N C+ PC +GG+C+P
Sbjct: 1297 QCPVGVPCQQTPRGPRCACPPGLSGPSCR----SFPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 431 DRNSWMNHTCDCPLGYAGASCQMP 502
+ C C G+ G C+ P
Sbjct: 1353 APLAPF-FRCACAQGWTGPRCEAP 1375
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ C NGG+C S +C+C PGYTG++C+ +PC PC
Sbjct: 924 DLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADPCLSRPCL 972
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+GG C + C C + G CQ
Sbjct: 973 HGGVCSAAHPGF---RCTCLESFTGPQCQ 998
Score = 50.4 bits (115), Expect = 4e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +2
Query: 263 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 96
Query: 434 -RNSWMNHTCDCPLGYAGASCQMP 502
+C CP G+ G C +P
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLP 120
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 899 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 946
Query: 449 NHTCDCPLGYAGASCQ 496
+C C GY GA CQ
Sbjct: 947 --SCLCRPGYTGAHCQ 960
Score = 49.2 bits (112), Expect = 9e-06
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +2
Query: 293 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 472
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 565 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 610
Query: 473 GYAGASCQMPLE 508
G G +C++ ++
Sbjct: 611 GTTGVNCEVNID 622
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 254
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 255 VNT---YNCQCPPEWTGQFC 271
Score = 48.0 bits (109), Expect = 2e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 449
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
TC C G+ G C++ ++ QS
Sbjct: 450 IG--QFTCICMAGFTGTYCEVDIDECQS 475
Score = 48.0 bits (109), Expect = 2e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 718 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 765
Query: 482 GASCQM 499
G C++
Sbjct: 766 GRQCEL 771
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1177
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ GTC + C CP GY G C+
Sbjct: 1178 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1203
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C NGGSC S +C C PG+ G C V+ C +PC
Sbjct: 849 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC- 896
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GTC S+ TC CP GY G C+ L
Sbjct: 897 GPGTCTDHVASF---TCTCPPGYGGFHCEQDL 925
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1138
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ + C CP G G C++
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEI 1159
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 406
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 402
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G C + S++ C C GY G C+
Sbjct: 403 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 429
Score = 44.0 bits (99), Expect = 3e-04
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G C+ S +C C GYTG C+ I N C +PC NGG+C+
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-----------NDCDPNPCLNGGSCQDGV 868
Query: 437 NSWMNHTCDCPLGYAGASC 493
S+ +C C G+AG C
Sbjct: 869 GSF---SCSCLPGFAGPRC 884
Score = 41.1 bits (92), Expect = 0.002
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 475
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1232 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
Query: 476 YAGASCQ 496
+ G C+
Sbjct: 1281 FWGPRCE 1287
Score = 40.7 bits (91), Expect = 0.003
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 140
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
C CP GY G SC+ ++
Sbjct: 141 --RFLCSCPPGYQGRSCRSDVD 160
Score = 40.7 bits (91), Expect = 0.003
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 358
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC C D N C CP G+ G +C ++
Sbjct: 359 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD 393
Score = 40.7 bits (91), Expect = 0.003
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 642 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 687
Query: 479 AGASCQMP 502
C P
Sbjct: 688 LPPLCLPP 695
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 1017
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
C CP G++G C +
Sbjct: 1018 ---TGAYCLCPPGWSGRLCDI 1035
Score = 39.9 bits (89), Expect = 0.005
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 705
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+ G C + C C G++G C L
Sbjct: 706 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 733
Score = 37.1 bits (82), Expect = 0.037
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG C + C CP G TG CE I + C+ +PC
Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI-----------DDCASNPC-T 630
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C+ N + C C G+ G C + +
Sbjct: 631 FGVCRDGIN---RYDCVCQPGFTGPLCNVEI 658
Score = 37.1 bits (82), Expect = 0.037
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1223
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
++ C C G++G CQ L
Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVL 1247
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
CE+GG C + C CP G+ G C+ + + P P P H G C
Sbjct: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPAPCGP---H-----GICTNL 829
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
S+ +C C GY G SC +
Sbjct: 830 AGSF---SCTCHGGYTGPSCDQDI 850
Score = 33.5 bits (73), Expect = 0.46
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Frame = +2
Query: 359 LMSPPPPVNPC-SLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM 499
L P PC PC NGG C P R + C CP G+ G CQ+
Sbjct: 33 LAGPGAAAPPCLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQL 78
Score = 33.1 bits (72), Expect = 0.61
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 8/86 (9%)
Frame = +2
Query: 263 CENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C +GGSC C C G+TG CE A+ +S P + R C
Sbjct: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1403
Query: 431 DRNS----WMNHTCDCPLGYAGASCQ 496
+ NS W C +G C+
Sbjct: 1404 ECNSPGCGWDGGDCSLSVGDPWRQCE 1429
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 128 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 174
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + + C C G+ G +C++ ++
Sbjct: 175 SGDLTYDCACLPGFEGQNCEVNVD 198
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1015 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1063
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+M C+C GY G +C+
Sbjct: 1064 GGYM---CECLPGYNGDNCE 1080
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 391 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 439
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG CK N + +C CP G++G++CQ+ ++
Sbjct: 440 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVD 469
Score = 57.6 bits (133), Expect = 2e-08
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 697 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 744
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C+ C CP G+ G CQ ++
Sbjct: 745 RCESAPGQL--PVCSCPQGWQGPRCQQDVD 772
Score = 55.6 bits (128), Expect = 1e-07
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 427
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 204 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 251
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ H+C C G+ G SC ++
Sbjct: 252 --FNTLGGHSCVCVNGWTGESCSQNID 276
Score = 54.4 bits (125), Expect = 2e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 969 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1027
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
H C CP G G+ C+ ++
Sbjct: 1028 ---HYCVCPEGRTGSHCEQEVD 1046
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 424 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 472
Query: 395 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 493
PCRNG C +PD + C C G+ G C
Sbjct: 473 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 502
Score = 52.8 bits (121), Expect = 7e-07
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 421
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 85 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 133
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMP 502
C N+ + C CP GY G C+ P
Sbjct: 134 C---LNTPGSFRCQCPAGYTGPLCENP 157
Score = 52.0 bits (119), Expect = 1e-06
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLHPCRNGGTCKP 430
QC G C + C CPPG +G C S+ SPP N C+ PC +GG+C+P
Sbjct: 1257 QCPVGVPCQQTPRGPRCACPPGLSGPSCR----SFPGSPPGASNASCAAAPCLHGGSCRP 1312
Query: 431 DRNSWMNHTCDCPLGYAGASCQMP 502
+ C C G+ G C+ P
Sbjct: 1313 APLAPF-FRCACAQGWTGPRCEAP 1335
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ C NGG+C S +C+C PGYTG++C+ +PC PC
Sbjct: 884 DLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADPCLSRPCL 932
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+GG C + C C + G CQ
Sbjct: 933 HGGVCSAAHPGF---RCTCLESFTGPQCQ 958
Score = 50.4 bits (115), Expect = 4e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +2
Query: 263 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 9 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 56
Query: 434 -RNSWMNHTCDCPLGYAGASCQMP 502
+C CP G+ G C +P
Sbjct: 57 VVAGTARFSCRCPRGFRGPDCSLP 80
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 859 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 906
Query: 449 NHTCDCPLGYAGASCQ 496
+C C GY GA CQ
Sbjct: 907 --SCLCRPGYTGAHCQ 920
Score = 49.2 bits (112), Expect = 9e-06
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +2
Query: 293 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 472
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 525 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 570
Query: 473 GYAGASCQMPLE 508
G G +C++ ++
Sbjct: 571 GTTGVNCEVNID 582
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 166 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 214
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 215 VNT---YNCQCPPEWTGQFC 231
Score = 48.0 bits (109), Expect = 2e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 362 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 409
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
TC C G+ G C++ ++ QS
Sbjct: 410 IG--QFTCICMAGFTGTYCEVDIDECQS 435
Score = 48.0 bits (109), Expect = 2e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 678 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 725
Query: 482 GASCQM 499
G C++
Sbjct: 726 GRQCEL 731
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1082 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1137
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ GTC + C CP GY G C+
Sbjct: 1138 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1163
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI + C NGGSC S +C C PG+ G C V+ C +PC
Sbjct: 809 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC- 856
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
GTC S+ TC CP GY G C+ L
Sbjct: 857 GPGTCTDHVASF---TCTCPPGYGGFHCEQDL 885
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1053 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1098
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ + C CP G G C++
Sbjct: 1099 DLVARYLCSCPPGTLGVLCEI 1119
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 406
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 314 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 362
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G C + S++ C C GY G C+
Sbjct: 363 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 389
Score = 44.0 bits (99), Expect = 3e-04
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G C+ S +C C GYTG C+ I N C +PC NGG+C+
Sbjct: 780 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-----------NDCDPNPCLNGGSCQDGV 828
Query: 437 NSWMNHTCDCPLGYAGASC 493
S+ +C C G+AG C
Sbjct: 829 GSF---SCSCLPGFAGPRC 844
Score = 41.1 bits (92), Expect = 0.002
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 475
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1192 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1240
Query: 476 YAGASCQ 496
+ G C+
Sbjct: 1241 FWGPRCE 1247
Score = 40.7 bits (91), Expect = 0.003
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 53 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 100
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
C CP GY G SC+ ++
Sbjct: 101 --RFLCSCPPGYQGRSCRSDVD 120
Score = 40.7 bits (91), Expect = 0.003
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 259 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 318
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC C D N C CP G+ G +C ++
Sbjct: 319 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD 353
Score = 40.7 bits (91), Expect = 0.003
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 602 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 647
Query: 479 AGASCQMP 502
C P
Sbjct: 648 LPPLCLPP 655
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 931 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 977
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
C CP G++G C +
Sbjct: 978 ---TGAYCLCPPGWSGRLCDI 995
Score = 39.9 bits (89), Expect = 0.005
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 617 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 665
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+ G C + C C G++G C L
Sbjct: 666 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 693
Score = 37.1 bits (82), Expect = 0.037
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG C + C CP G TG CE I + C+ +PC
Sbjct: 543 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI-----------DDCASNPC-T 590
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C+ N + C C G+ G C + +
Sbjct: 591 FGVCRDGIN---RYDCVCQPGFTGPLCNVEI 618
Score = 37.1 bits (82), Expect = 0.037
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1135 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1183
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
++ C C G++G CQ L
Sbjct: 1184 QDPGGGFRCLCHAGFSGPRCQTVL 1207
Score = 34.7 bits (76), Expect = 0.20
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
CE+GG C + C CP G+ G C+ + + P P P H G C
Sbjct: 740 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPAPCGP---H-----GICTNL 789
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
S+ +C C GY G SC +
Sbjct: 790 AGSF---SCTCHGGYTGPSCDQDI 810
Score = 33.1 bits (72), Expect = 0.61
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 8/86 (9%)
Frame = +2
Query: 263 CENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C +GGSC C C G+TG CE A+ +S P + R C
Sbjct: 1304 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1363
Query: 431 DRNS----WMNHTCDCPLGYAGASCQ 496
+ NS W C +G C+
Sbjct: 1364 ECNSPGCGWDGGDCSLSVGDPWRQCE 1389
Score = 31.9 bits (69), Expect = 1.4
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Frame = +2
Query: 401 PCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM 499
PC NGG C P R + C CP G+ G CQ+
Sbjct: 8 PCANGGRCTQLPSREA----ACLCPPGWVGERCQL 38
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 61.3 bits (142), Expect = 2e-09
Identities = 37/103 (35%), Positives = 43/103 (41%), Gaps = 2/103 (1%)
Frame = +2
Query: 200 SNIQECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP 379
S +Q C GD SC C+NGG+C S +C CP G+ G CE P
Sbjct: 1103 SCLQACPAGLYGD-NCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECL------PRD 1155
Query: 380 VNPCSLHP--CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
V H C NGG C P C CP G+ G CQ P
Sbjct: 1156 VRAGCRHSGGCLNGGLCDPHTG-----RCLCPAGWTGDKCQSP 1193
Score = 56.4 bits (130), Expect = 6e-08
Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PCSLH- 400
+R + +C C NGG C + +C C G+TG +CE L PP C L
Sbjct: 1370 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAACHLEC 1423
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C N TC+P TC C G+ G +C+ P G
Sbjct: 1424 SCHNNSTCEP-----ATGTCRCGPGFYGQACEHPCPPG 1456
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/96 (32%), Positives = 43/96 (44%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+ C + G S++C C NG SC C C PG+ G C + L N
Sbjct: 1063 ETCPAHTYGH-NCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGD----NC 1117
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+NGGTC P ++ C CP G+AG +C+
Sbjct: 1118 RHSCLCQNGGTCDP-----VSGHCACPEGWAGLACE 1148
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1337 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1391
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQ 517
N +C C LG+ G C++ G+
Sbjct: 1392 ----NGSCSCGLGWTGRHCELACPPGR 1414
Score = 50.4 bits (115), Expect = 4e-06
Identities = 27/80 (33%), Positives = 33/80 (41%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C NGGSC + C CP G+ G+ C P N + C G C P
Sbjct: 1294 CGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGP----NCTHVCGCGQGAACDP-- 1347
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ TC CP G AG C+
Sbjct: 1348 ---VTGTCLCPPGRAGVRCE 1364
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 436
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 602 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 653
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G +G +C+
Sbjct: 654 ---VTGACRCPPGVSGTNCE 670
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK 427
+ C C+ G C + C+CPPG +G+ C P C+LH C G C
Sbjct: 1507 QRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP-----SCTLHCDCGGGADCD 1561
Query: 428 PDRNSWMNHTCDCPLGYAGASCQM--PLELGQS 520
P ++ C C GY G +C+ PL L ++
Sbjct: 1562 P-----VSGQCHCVDGYMGPTCREGGPLRLPEN 1589
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +2
Query: 230 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 852 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 907
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
N G C P C C G+ G SCQ + G
Sbjct: 908 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 938
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/88 (30%), Positives = 36/88 (40%), Gaps = 1/88 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 433
C C++G C S C+CP G+ G +CE P C C G C P
Sbjct: 1466 CWCQHGAPCDPISGRCLCPAGFHGHFCERG-----CEPGSFGEGCHQRCDCDGGAPCDP- 1519
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQ 517
+ C CP G +GA+C + GQ
Sbjct: 1520 ----VTGLCLCPPGRSGATCNLDCRRGQ 1543
Score = 46.4 bits (105), Expect = 6e-05
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C+T G S C C G GSC S C+C GY G CE + P
Sbjct: 935 CDTGHWGP-DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE---- 989
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
L C++G C ++ C CP G+ G C+
Sbjct: 990 QLCQCQHGAAC-----DHVSGACTCPAGWRGTFCE 1019
Score = 46.4 bits (105), Expect = 6e-05
Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG--- 418
++ C C +C + C CPPG+TGS CE PP C+ G
Sbjct: 1204 AQRCSCPPAAACHHVTGACRCPPGFTGSGCEQ------ACPPGSFGEDCAQMCQCPGENP 1257
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
C P TC C GY G SCQ
Sbjct: 1258 ACHP-----ATGTCSCAAGYHGPSCQ 1278
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 424
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 684 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 737
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
D+ + +C C G+ G CQ ELG
Sbjct: 738 SCDKR---DGSCSCKAGFRGERCQAECELG 764
Score = 46.0 bits (104), Expect = 8e-05
Identities = 24/79 (30%), Positives = 35/79 (44%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 992 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA-- 1045
Query: 437 NSWMNHTCDCPLGYAGASC 493
+N +C CP G G C
Sbjct: 1046 ---VNGSCLCPAGRRGPRC 1061
Score = 45.6 bits (103), Expect = 1e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCE 340
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 640 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 670
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 433
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 905 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 958
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
S + C C GY G C+ G
Sbjct: 959 AISGL---CLCEAGYVGPRCEQQCPQG 982
Score = 45.2 bits (102), Expect = 1e-04
Identities = 31/106 (29%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGG-SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN 385
Q C G+ ++ CQC +C + C C GY G C+ R PP
Sbjct: 1235 QACPPGSFGE-DCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQR------CPPGRYG 1287
Query: 386 P-C-SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
P C L C NGG+C + C CP G+ G C + G+
Sbjct: 1288 PGCEQLCGCLNGGSCDAATGA-----CRCPTGFLGTDCNLTCPQGR 1328
Score = 43.6 bits (98), Expect = 4e-04
Identities = 22/85 (25%), Positives = 34/85 (40%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ +C C G +C + +C+CP G G C ++ N C NG
Sbjct: 1029 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGH----NCSQACACFNGA 1084
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASC 493
+C P ++ C C G+ G SC
Sbjct: 1085 SCDP-----VHGQCHCAPGWMGPSC 1104
Score = 42.3 bits (95), Expect = 0.001
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
QEC G + S SC C G C + C CPPG TG CE +
Sbjct: 804 QECPVGTFG-VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGC 857
Query: 389 CSLHP-CRNGGTCKPDRNS------WMNHTCD--CPLGYAGASCQ 496
+ P C++ C P+ + ++ C CP G+ G SCQ
Sbjct: 858 QEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 902
Score = 33.1 bits (72), Expect = 0.61
Identities = 19/60 (31%), Positives = 20/60 (33%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C G C S C C GY G C L P S H R T P+R
Sbjct: 1552 CDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGLSGHTARLQQTHIPER 1611
Score = 31.5 bits (68), Expect = 1.9
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Frame = +2
Query: 263 CENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 439
C +GG C S C CPPG+ G C+ V+ C H NGG N
Sbjct: 208 CFHGGRCVPGSAQPCHCPPGFQGPRCQY-----------DVDECRTH---NGGCQHRCVN 253
Query: 440 SWMNHTCDCPLGY 478
+ ++ C+C G+
Sbjct: 254 TPGSYLCECKPGF 266
Score = 30.3 bits (65), Expect = 4.3
Identities = 14/40 (35%), Positives = 18/40 (45%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
CS C +GG C P C CP G+ G CQ ++
Sbjct: 203 CSAGLCFHGGRCVPGSAQ----PCHCPPGFQGPRCQYDVD 238
Score = 29.9 bits (64), Expect = 5.7
Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 9/103 (8%)
Frame = +2
Query: 212 ECNTYDRGDIQ-ASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN- 385
EC+ ++ + A+ +C+C G ++ CPPG+ G+ C+ +P P++
Sbjct: 1422 ECSCHNNSTCEPATGTCRC--GPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG 1479
Query: 386 ----PCSLHP--CRNGGTCKPDR-NSWMNHTCDCPLGYAGASC 493
P H C G C+P + CDC GA C
Sbjct: 1480 RCLCPAGFHGHFCERG--CEPGSFGEGCHQRCDCD---GGAPC 1517
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 171 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 217
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ + + C C G+ G +C++ ++
Sbjct: 218 SGDLTYDCACLPGFEGQNCEVNVD 241
Score = 61.3 bits (142), Expect = 2e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1006 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1054
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+M C+C GY G +C+
Sbjct: 1055 GGYM---CECLPGYNGDNCE 1071
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 434 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 482
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG CK N + +C CP G++G++CQ+ ++
Sbjct: 483 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVD 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 427
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 247 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 294
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N+ H+C C G+ G SC ++
Sbjct: 295 --FNTLGGHSCVCVNGWTGESCSQNID 319
Score = 54.4 bits (125), Expect = 2e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 960 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1018
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
H C CP G G+ C+ ++
Sbjct: 1019 ---HYCVCPEGRTGSHCEQEVD 1037
Score = 53.2 bits (122), Expect = 5e-07
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 467 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 515
Query: 395 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 493
PCRNG C +PD + C C G+ G C
Sbjct: 516 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 545
Score = 52.8 bits (121), Expect = 7e-07
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 421
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 128 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 176
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMP 502
C N+ + C CP GY G C+ P
Sbjct: 177 C---LNTPGSFRCQCPAGYTGPLCENP 200
Score = 51.6 bits (118), Expect = 2e-06
Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Frame = +2
Query: 245 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 740 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 787
Query: 419 TCKPDRNSWMNHTCDCPLGYA-----GASCQ 496
C+ C CP G+ G SCQ
Sbjct: 788 RCESAPGQL--PVCSCPQGWQDPCLNGGSCQ 816
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ C NGG+C S +C+C PGYTG++C+ +PC PC
Sbjct: 875 DLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADPCLSRPCL 923
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+GG C + C C + G CQ
Sbjct: 924 HGGVCSAAHPGF---RCTCLESFTGPQCQ 949
Score = 50.4 bits (115), Expect = 4e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +2
Query: 263 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 52 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 99
Query: 434 -RNSWMNHTCDCPLGYAGASCQMP 502
+C CP G+ G C +P
Sbjct: 100 VVAGTARFSCRCPRGFRGPDCSLP 123
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 850 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 897
Query: 449 NHTCDCPLGYAGASCQ 496
+C C GY GA CQ
Sbjct: 898 --SCLCRPGYTGAHCQ 911
Score = 49.2 bits (112), Expect = 9e-06
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +2
Query: 293 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 472
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 568 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 613
Query: 473 GYAGASCQMPLE 508
G G +C++ ++
Sbjct: 614 GTTGVNCEVNID 625
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 209 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 257
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N+ + C CP + G C
Sbjct: 258 VNT---YNCQCPPEWTGQFC 274
Score = 48.0 bits (109), Expect = 2e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 405 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 452
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
TC C G+ G C++ ++ QS
Sbjct: 453 IG--QFTCICMAGFTGTYCEVDIDECQS 478
Score = 48.0 bits (109), Expect = 2e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 721 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 768
Query: 482 GASCQM 499
G C++
Sbjct: 769 GRQCEL 774
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1073 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1128
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ GTC + C CP GY G C+
Sbjct: 1129 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1154
Score = 45.6 bits (103), Expect = 1e-04
Identities = 30/83 (36%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSC S +C C PG+ G C V+ C +PC GTC
Sbjct: 809 CLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC-GPGTCTDHV 856
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ TC CP GY G C+ L
Sbjct: 857 ASF---TCTCPPGYGGFHCEQDL 876
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1044 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1089
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ + C CP G G C++
Sbjct: 1090 DLVARYLCSCPPGTLGVLCEI 1110
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 406
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 357 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 405
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ G C + S++ C C GY G C+
Sbjct: 406 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 432
Score = 41.1 bits (92), Expect = 0.002
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 475
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1183 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1231
Query: 476 YAGASCQ 496
+ G C+
Sbjct: 1232 FWGPRCE 1238
Score = 40.7 bits (91), Expect = 0.003
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 96 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 143
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
C CP GY G SC+ ++
Sbjct: 144 --RFLCSCPPGYQGRSCRSDVD 163
Score = 40.7 bits (91), Expect = 0.003
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 400
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 302 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 361
Query: 401 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 508
PC C D N C CP G+ G +C ++
Sbjct: 362 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD 396
Score = 40.7 bits (91), Expect = 0.003
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +2
Query: 299 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 645 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 690
Query: 479 AGASCQMP 502
C P
Sbjct: 691 LPPLCLPP 698
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 922 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 968
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
C CP G++G C +
Sbjct: 969 ---TGAYCLCPPGWSGRLCDI 986
Score = 39.9 bits (89), Expect = 0.005
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 660 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 708
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+ G C + C C G++G C L
Sbjct: 709 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 736
Score = 37.1 bits (82), Expect = 0.037
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 2/91 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG C + C CP G TG CE I + C+ +PC
Sbjct: 586 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI-----------DDCASNPC-T 633
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C+ N + C C G+ G C + +
Sbjct: 634 FGVCRDGIN---RYDCVCQPGFTGPLCNVEI 661
Score = 37.1 bits (82), Expect = 0.037
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1126 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1174
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
++ C C G++G CQ L
Sbjct: 1175 QDPGGGFRCLCHAGFSGPRCQTVL 1198
Score = 33.5 bits (73), Expect = 0.46
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Frame = +2
Query: 359 LMSPPPPVNPC-SLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM 499
L P PC PC NGG C P R + C CP G+ G CQ+
Sbjct: 36 LAGPGAAAPPCLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQL 81
>AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein.
Length = 1123
Score = 60.9 bits (141), Expect = 3e-09
Identities = 45/139 (32%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Frame = +2
Query: 104 NPNAGVS-GGFSGCIKDVVLNSNAVDINSSIKS-SNIQECNTYDRGDIQASESCQ--CEN 271
N A VS GF GC+ VV+N A+D+ + K+ + + E + + + Q C N
Sbjct: 673 NETASVSLKGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLN 732
Query: 272 GGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
GG CS T C CPP ++G +CE + C+ PC GGTC S
Sbjct: 733 GGKCSWTHGAGYVCKCPPQFSGKHCEQGREN-----------CTFAPCLEGGTC---ILS 778
Query: 443 WMNHTCDCPLGYAGASCQM 499
+C+CP Y G C+M
Sbjct: 779 PKGASCNCPHPYTGDRCEM 797
>U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein
Del-1 protein.
Length = 125
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
+ +GDI + CENGG C + S +C CP G+T C + + V PC
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVE---------VGPC 68
Query: 392 SLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 496
+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 69 TPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 107
Score = 39.1 bits (87), Expect = 0.009
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C +PC NGG C P + +C+CP G+ +C +E+G
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEVG 66
Score = 37.5 bits (83), Expect = 0.028
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 9/63 (14%)
Frame = +2
Query: 263 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 73 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 121
Query: 416 GTC 424
G C
Sbjct: 122 GIC 124
>BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 60.5 bits (140), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLLSV 1168
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 47.2 bits (107), Expect = 3e-05
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1278 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1337
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1338 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1378
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC H C +G C P ++++C C GY+GA C
Sbjct: 1379 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALC 1412
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.028
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 3.2
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +2
Query: 260 QCENGG--SCSTESTNCICPPGYTGSYCE 340
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein.
Length = 470
Score = 60.5 bits (140), Expect = 3e-09
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
+ +GDI + CENGG C + S +C CP G+T C + + V PC
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVE---------VGPC 68
Query: 392 SLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 496
+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 69 TPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 107
Score = 50.0 bits (114), Expect = 5e-06
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +2
Query: 263 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 73 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 121
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQ 496
G C + N++C+CP + G +CQ
Sbjct: 122 GIC---TDLVANYSCECPGEFMGRNCQ 145
Score = 39.1 bits (87), Expect = 0.009
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C +PC NGG C P + +C+CP G+ +C +E+G
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEVG 66
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 60.5 bits (140), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLLSV 1168
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 47.2 bits (107), Expect = 3e-05
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1278 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1337
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1338 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1378
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC H C +G C P ++++C C GY+GA C
Sbjct: 1379 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALC 1412
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.028
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 3.2
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +2
Query: 260 QCENGG--SCSTESTNCICPPGYTGSYCE 340
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 60.5 bits (140), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLLSV 1168
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 7/164 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1278 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1337
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1338 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1378
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
PC H C +G C P ++++C C GY+GA C G
Sbjct: 1379 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALCNQSPSAG 1419
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.028
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
>AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 60.5 bits (140), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLLSV 1168
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 47.2 bits (107), Expect = 3e-05
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1278 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1337
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1338 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1378
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC H C +G C P ++++C C GY+GA C
Sbjct: 1379 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALC 1412
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.028
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 3.2
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +2
Query: 260 QCENGG--SCSTESTNCICPPGYTGSYCE 340
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 60.5 bits (140), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLLSV 1168
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 7/164 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1278 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1337
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1338 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1378
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
PC H C +G C P ++++C C GY+GA C G
Sbjct: 1379 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALCNQSPSAG 1419
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.028
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 60.5 bits (140), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +2
Query: 254 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 1015 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 1063
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
TC CP G+ G +C
Sbjct: 1064 HAQEGEDAPFTCSCPTGFEGPTC 1086
Score = 56.8 bits (131), Expect = 4e-08
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1175 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1229
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
N C C G+ G C+ L +
Sbjct: 1230 GN---RPVCQCLPGFGGPECEKLLSV 1252
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 1049 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1097
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1098 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1130
Score = 47.2 bits (107), Expect = 3e-05
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Frame = +2
Query: 44 SLRFETPMFVGG--VDDSTVVVNPNAGVSG-GFSGCIKDVVLNSNAVDINSS-IKSSNIQ 211
+L E P++VGG VD ++ ++G GF GCI+++ +N+ D + +K +
Sbjct: 1362 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVP 1421
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
C + C +G C +T C C G+ G +C+ P
Sbjct: 1422 GC--------EPCRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQ----------PAD 1462
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC H C +G C P ++++C C GY+GA C
Sbjct: 1463 GPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALC 1496
Score = 45.2 bits (102), Expect = 1e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1129 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1177
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
NG C + NS ++C C GY+G C++P L
Sbjct: 1178 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1208
Score = 37.5 bits (83), Expect = 0.028
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 1013 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 1050
Score = 31.5 bits (68), Expect = 1.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
E +C+NG +C + C C PG+ G CE
Sbjct: 1216 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1247
Score = 30.7 bits (66), Expect = 3.2
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +2
Query: 260 QCENGG--SCSTESTNCICPPGYTGSYCE 340
QC +G + T+ +C+C PG++G CE
Sbjct: 1510 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1538
>U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged
protein.
Length = 263
Score = 60.1 bits (139), Expect = 5e-09
Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C + ES C+C G+ G C N CS HPC N GTC D
Sbjct: 11 CHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPHPCYNSGTC-VDG 58
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
++W + C+C G+AG C++ + QS
Sbjct: 59 DNW--YRCECAPGFAGPDCRININECQS 84
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 49 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 97
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
N + C CP G++GA CQ
Sbjct: 98 NGYR---CVCPPGHSGAKCQ 114
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 403
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 76 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 120
Query: 404 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 490
C G+ PD W + +TC C G S
Sbjct: 121 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 151
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/35 (42%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 6 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 37
>D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.
Length = 2854
Score = 60.1 bits (139), Expect = 5e-09
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 5/142 (3%)
Frame = +2
Query: 98 VVNPNAGVSGGFSGCIKDVVLNSNAVDINSSI----KSSNIQE-CNTYDRGDIQASESCQ 262
+ P GV+ GF GC++ V ++ +NS +S N+++ C+ D D S C
Sbjct: 1678 IPGPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCD---SNPCP 1734
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
+ S +S +C C PGY G C N C L+PC + C ++
Sbjct: 1735 ANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVCTRKPSA 1780
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
+TC+CP Y G C+ ++
Sbjct: 1781 PHGYTCECPPNYLGPYCETRID 1802
Score = 47.6 bits (108), Expect = 3e-05
Identities = 19/41 (46%), Positives = 23/41 (56%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P N C + C NGGTC N W +C+CPLG+ G SC
Sbjct: 1503 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSC 1540
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1205 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1250
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1251 GEHCEVSARSGR 1262
Score = 39.9 bits (89), Expect = 0.005
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1215 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1265
Query: 398 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQM 499
C+NGGTC N + CDCP G + CQ+
Sbjct: 1266 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQV 1298
>AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 2 (flamingo homolog, Drosophila) protein.
Length = 2923
Score = 60.1 bits (139), Expect = 5e-09
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 5/142 (3%)
Frame = +2
Query: 98 VVNPNAGVSGGFSGCIKDVVLNSNAVDINSSI----KSSNIQE-CNTYDRGDIQASESCQ 262
+ P GV+ GF GC++ V ++ +NS +S N+++ C+ D D S C
Sbjct: 1747 IPGPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCD---SNPCP 1803
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
+ S +S +C C PGY G C N C L+PC + C ++
Sbjct: 1804 ANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVCTRKPSA 1849
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
+TC+CP Y G C+ ++
Sbjct: 1850 PHGYTCECPPNYLGPYCETRID 1871
Score = 47.6 bits (108), Expect = 3e-05
Identities = 19/41 (46%), Positives = 23/41 (56%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P N C + C NGGTC N W +C+CPLG+ G SC
Sbjct: 1572 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSC 1609
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1274 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1319
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1320 GEHCEVSARSGR 1331
Score = 39.9 bits (89), Expect = 0.005
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1334
Query: 398 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQM 499
C+NGGTC N + CDCP G + CQ+
Sbjct: 1335 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQV 1367
>AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/92 (32%), Positives = 39/92 (42%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ S +C C+NGG+C E+ NC+C PG+ G C+ P C C N
Sbjct: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS-----CQPGRYGKRCVPCKCANHS 628
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C P N TC C G+ G C P G
Sbjct: 629 FCHPS-----NGTCYCLAGWTGPDCSQPCPPG 655
Score = 56.0 bits (129), Expect = 8e-08
Identities = 27/87 (31%), Positives = 44/87 (50%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
+++CQC +GG+C + +CICP G+TG +C PC C G C
Sbjct: 662 AQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS-QPCQ---CGPGEKCH 717
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
P+ + C CP G++GA C++ ++
Sbjct: 718 PETGA-----CVCPPGHSGAPCRIGIQ 739
Score = 54.0 bits (124), Expect = 3e-07
Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 12/98 (12%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP----VNPCSLHPCRNGGTC 424
C+C N C + C C G+TG C P PP N C +GGTC
Sbjct: 622 CKCANHSFCHPSNGTCYCLAGWTGPDCS--------QPCPPGHWGENCAQTCQCHHGGTC 673
Query: 425 KPDRNS------WMNHTC--DCPLGYAGASCQMPLELG 514
P S W H C CPLG GA+C P + G
Sbjct: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 711
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/87 (31%), Positives = 37/87 (42%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C++ C C C G+ G+ C L VN + C+NGGTC P+
Sbjct: 537 CDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG----VNCSNTCTCKNGGTCLPE- 591
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQ 517
N C C G+ G SCQ + G+
Sbjct: 592 ----NGNCVCAPGFRGPSCQRSCQPGR 614
Score = 49.2 bits (112), Expect = 9e-06
Identities = 29/88 (32%), Positives = 37/88 (42%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
E C C +GG C S C C PGYTG +C AS VN + C N C P
Sbjct: 406 EHCLCLHGGVCQATSGLCQCAPGYTGPHC----ASLCPPDTYGVNCSARCSCENAIACSP 461
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
++ C C G+ +C +P G
Sbjct: 462 -----IDGECVCKEGWQRGNCSVPCPPG 484
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG T +C CPPG+ G+ C P N C NGG C DR
Sbjct: 235 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGLC--DR-- 286
Query: 443 WMNHTCDCPLGYAGASCQMPLELGQ 517
C C GY G C+ +G+
Sbjct: 287 -FTGQCRCAPGYTGDRCREECPVGR 310
Score = 47.6 bits (108), Expect = 3e-05
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 5/90 (5%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPC-RNGG 418
S+ C+C NGG C + C C PGYTG C E + + + C G
Sbjct: 273 SQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANG 332
Query: 419 TCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C + + D CP G+ G SCQ P
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 362
Score = 45.2 bits (102), Expect = 1e-04
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 4/101 (3%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN---PCSL 397
D + S C CEN +CS C+C G+ C P PP C+
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV--------PCPPGTWGFSCNA 492
Query: 398 H-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
C + C P + C C G+ GA CQ+P GQ
Sbjct: 493 SCQCAHEAVCSPQTGA-----CTCTPGWHGAHCQLPCPKGQ 528
Score = 41.5 bits (93), Expect = 0.002
Identities = 22/82 (26%), Positives = 34/82 (41%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
SCQC + CS ++ C C PG+ G++C+ S C + C P
Sbjct: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE----GCASRCDCDHSDGCDP- 547
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
++ C C G+ GA C +
Sbjct: 548 ----VHGRCQCQAGWMGARCHL 565
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/95 (27%), Positives = 37/95 (38%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G +E+C C C + C+C G+TG C R+ P
Sbjct: 304 EECPVGRFGQ-DCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 362
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C+ + +C P MN C C G+AG C
Sbjct: 363 CTCDR-EHSLSCHP-----MNGECSCLPGWAGLHC 391
Score = 39.1 bits (87), Expect = 0.009
Identities = 26/93 (27%), Positives = 30/93 (32%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
Q + C C N SC +S C CP G C P C H G
Sbjct: 143 QCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR-CQCH----GAP 197
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
C P + C CP G SC + G S
Sbjct: 198 CDPQTGA-----CFCPAERTGPSCDVSCSQGTS 225
Score = 38.3 bits (85), Expect = 0.016
Identities = 24/80 (30%), Positives = 31/80 (38%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNH 454
G C + C C PG+ G C + A + P PCS C N +C P +
Sbjct: 112 GRCVAPN-QCQCVPGWRGDDCSSECAPGMWGPQCD-KPCS---CGNNSSCDP-----KSG 161
Query: 455 TCDCPLGYAGASCQMPLELG 514
C CP G +C P G
Sbjct: 162 VCSCPSGLQPPNCLQPCTPG 181
>AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/92 (32%), Positives = 39/92 (42%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ S +C C+NGG+C E+ NC+C PG+ G C+ P C C N
Sbjct: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS-----CQPGRYGKRCVPCKCANHS 628
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C P N TC C G+ G C P G
Sbjct: 629 FCHPS-----NGTCYCLAGWTGPDCSQPCPPG 655
Score = 56.0 bits (129), Expect = 8e-08
Identities = 27/87 (31%), Positives = 44/87 (50%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
+++CQC +GG+C + +CICP G+TG +C PC C G C
Sbjct: 662 AQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS-QPCQ---CGPGEKCH 717
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
P+ + C CP G++GA C++ ++
Sbjct: 718 PETGA-----CVCPPGHSGAPCRIGIQ 739
Score = 54.0 bits (124), Expect = 3e-07
Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 12/98 (12%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP----VNPCSLHPCRNGGTC 424
C+C N C + C C G+TG C P PP N C +GGTC
Sbjct: 622 CKCANHSFCHPSNGTCYCLAGWTGPDCS--------QPCPPGHWGENCAQTCQCHHGGTC 673
Query: 425 KPDRNS------WMNHTC--DCPLGYAGASCQMPLELG 514
P S W H C CPLG GA+C P + G
Sbjct: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 711
Score = 51.6 bits (118), Expect = 2e-06
Identities = 27/87 (31%), Positives = 37/87 (42%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C++ C C C G+ G+ C L VN + C+NGGTC P+
Sbjct: 537 CDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG----VNCSNTCTCKNGGTCLPE- 591
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQ 517
N C C G+ G SCQ + G+
Sbjct: 592 ----NGNCVCAPGFRGPSCQRSCQPGR 614
Score = 49.2 bits (112), Expect = 9e-06
Identities = 29/88 (32%), Positives = 37/88 (42%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
E C C +GG C S C C PGYTG +C AS VN + C N C P
Sbjct: 406 EHCLCLHGGVCQATSGLCQCAPGYTGPHC----ASLCPPDTYGVNCSARCSCENAIACSP 461
Query: 431 DRNSWMNHTCDCPLGYAGASCQMPLELG 514
++ C C G+ +C +P G
Sbjct: 462 -----IDGECVCKEGWQRGNCSVPCPPG 484
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG T +C CPPG+ G+ C P N C NGG C DR
Sbjct: 235 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGLC--DR-- 286
Query: 443 WMNHTCDCPLGYAGASCQMPLELGQ 517
C C GY G C+ +G+
Sbjct: 287 -FTGQCRCAPGYTGDRCREECPVGR 310
Score = 47.6 bits (108), Expect = 3e-05
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 5/90 (5%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPC-RNGG 418
S+ C+C NGG C + C C PGYTG C E + + + C G
Sbjct: 273 SQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANG 332
Query: 419 TCKPDRNSWMNHTCD--CPLGYAGASCQMP 502
C + + D CP G+ G SCQ P
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 362
Score = 45.2 bits (102), Expect = 1e-04
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 4/101 (3%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN---PCSL 397
D + S C CEN +CS C+C G+ C P PP C+
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV--------PCPPGTWGFSCNA 492
Query: 398 H-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
C + C P + C C G+ GA CQ+P GQ
Sbjct: 493 SCQCAHEAVCSPQTGA-----CTCTPGWHGAHCQLPCPKGQ 528
Score = 41.5 bits (93), Expect = 0.002
Identities = 22/82 (26%), Positives = 34/82 (41%)
Frame = +2
Query: 254 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
SCQC + CS ++ C C PG+ G++C+ S C + C P
Sbjct: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE----GCASRCDCDHSDGCDP- 547
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
++ C C G+ GA C +
Sbjct: 548 ----VHGRCQCQAGWMGARCHL 565
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/95 (27%), Positives = 37/95 (38%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G +E+C C C + C+C G+TG C R+ P
Sbjct: 304 EECPVGRFGQ-DCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 362
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C+ + +C P MN C C G+AG C
Sbjct: 363 CTCDR-EHSLSCHP-----MNGECSCLPGWAGLHC 391
Score = 39.1 bits (87), Expect = 0.009
Identities = 26/93 (27%), Positives = 30/93 (32%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
Q + C C N SC +S C CP G C P C H G
Sbjct: 143 QCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR-CQCH----GAP 197
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
C P + C CP G SC + G S
Sbjct: 198 CDPQTGA-----CFCPAERTGPSCDVSCSQGTS 225
Score = 38.3 bits (85), Expect = 0.016
Identities = 24/80 (30%), Positives = 31/80 (38%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNH 454
G C + C C PG+ G C + A + P PCS C N +C P +
Sbjct: 112 GRCVAPN-QCQCVPGWRGDDCSSECAPGMWGPQCD-KPCS---CGNNSSCDP-----KSG 161
Query: 455 TCDCPLGYAGASCQMPLELG 514
C CP G +C P G
Sbjct: 162 VCSCPSGLQPPNCLQPCTPG 181
>AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein.
Length = 491
Score = 60.1 bits (139), Expect = 5e-09
Identities = 30/92 (32%), Positives = 39/92 (42%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+ S +C C+NGG+C E+ NC+C PG+ G C+ P C C N
Sbjct: 28 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS-----CQPGRYGKRCVPCKCANHS 82
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C P N TC C G+ G C P G
Sbjct: 83 FCHPS-----NGTCYCLAGWTGPDCSQPCPPG 109
Score = 56.0 bits (129), Expect = 8e-08
Identities = 27/87 (31%), Positives = 44/87 (50%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
+++CQC +GG+C + +CICP G+TG +C PC C G C
Sbjct: 116 AQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS-QPCQ---CGPGEKCH 171
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
P+ + C CP G++GA C++ ++
Sbjct: 172 PETGA-----CVCPPGHSGAPCRIGIQ 193
Score = 54.0 bits (124), Expect = 3e-07
Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 12/98 (12%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP----VNPCSLHPCRNGGTC 424
C+C N C + C C G+TG C P PP N C +GGTC
Sbjct: 76 CKCANHSFCHPSNGTCYCLAGWTGPDCS--------QPCPPGHWGENCAQTCQCHHGGTC 127
Query: 425 KPDRNS------WMNHTC--DCPLGYAGASCQMPLELG 514
P S W H C CPLG GA+C P + G
Sbjct: 128 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 165
Score = 37.1 bits (82), Expect = 0.037
Identities = 18/46 (39%), Positives = 24/46 (52%)
Frame = +2
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
VN + C+NGGTC P+ N C C G+ G SCQ + G+
Sbjct: 28 VNCSNTCTCKNGGTCLPE-----NGNCVCAPGFRGPSCQRSCQPGR 68
>AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.
Length = 2923
Score = 60.1 bits (139), Expect = 5e-09
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 5/142 (3%)
Frame = +2
Query: 98 VVNPNAGVSGGFSGCIKDVVLNSNAVDINSSI----KSSNIQE-CNTYDRGDIQASESCQ 262
+ P GV+ GF GC++ V ++ +NS +S N+++ C+ D D S C
Sbjct: 1747 IPGPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCD---SNPCP 1803
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
+ S +S +C C PGY G C N C L+PC + C ++
Sbjct: 1804 ANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVCTRKPSA 1849
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
+TC+CP Y G C+ ++
Sbjct: 1850 PHGYTCECPPNYLGPYCETRID 1871
Score = 47.6 bits (108), Expect = 3e-05
Identities = 19/41 (46%), Positives = 23/41 (56%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P N C + C NGGTC N W +C+CPLG+ G SC
Sbjct: 1572 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSC 1609
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1274 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1319
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1320 GEHCEVSARSGR 1331
Score = 39.9 bits (89), Expect = 0.005
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1334
Query: 398 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQM 499
C+NGGTC N + CDCP G + CQ+
Sbjct: 1335 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQV 1367
>AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix
receptor protein.
Length = 2923
Score = 60.1 bits (139), Expect = 5e-09
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 5/142 (3%)
Frame = +2
Query: 98 VVNPNAGVSGGFSGCIKDVVLNSNAVDINSSI----KSSNIQE-CNTYDRGDIQASESCQ 262
+ P GV+ GF GC++ V ++ +NS +S N+++ C+ D D S C
Sbjct: 1747 IPGPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCD---SNPCP 1803
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
+ S +S +C C PGY G C N C L+PC + C ++
Sbjct: 1804 ANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVCTRKPSA 1849
Query: 443 WMNHTCDCPLGYAGASCQMPLE 508
+TC+CP Y G C+ ++
Sbjct: 1850 PHGYTCECPPNYLGPYCETRID 1871
Score = 47.6 bits (108), Expect = 3e-05
Identities = 19/41 (46%), Positives = 23/41 (56%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
P N C + C NGGTC N W +C+CPLG+ G SC
Sbjct: 1572 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSC 1609
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1274 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1319
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1320 GEHCEVSARSGR 1331
Score = 39.9 bits (89), Expect = 0.005
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1334
Query: 398 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQM 499
C+NGGTC N + CDCP G + CQ+
Sbjct: 1335 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQV 1367
>AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein.
Length = 291
Score = 59.7 bits (138), Expect = 6e-09
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Frame = +2
Query: 251 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 68 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 116
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
PCRNG TC +S TC CP GY G++C+
Sbjct: 117 PCRNGATC---ISSLSGFTCQCPEGYFGSACE 145
Score = 59.3 bits (137), Expect = 8e-09
Identities = 39/119 (32%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQ-ECNTYDRGDIQAS--ESC---QCENGGSC--STESTNCICPP 316
N++ +D N SN C G++ S + C C NG +C S C CP
Sbjct: 78 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPE 137
Query: 317 GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
GY GS CE + V+PC+ PC+N GTC D ++ TC+C G+ G +C
Sbjct: 138 GYFGSACEEK-----------VDPCASSPCQNNGTCYVD---GVHFTCNCSPGFTGPTC 182
Score = 45.2 bits (102), Expect = 1e-04
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 188 SIKSSNIQECNTYDRGDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIAS 355
+++ + + + +T G+ A++ +C G C+T E+T +C C Y G++CE A
Sbjct: 12 ALRLTLVVKVSTCVPGESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDA- 69
Query: 356 YLMSPPPPVNPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C PC+N +C ++ N TC C GY G CQ ++
Sbjct: 70 -----------CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 111
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 153 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 199
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
R+ ++ C C GY G C+
Sbjct: 200 --RSVGTSYKCLCDPGYHGLYCE 220
Score = 43.2 bits (97), Expect = 6e-04
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +2
Query: 275 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 197 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 242
Query: 449 NHTCDCPLGYAGASCQM 499
+ C C Y G C++
Sbjct: 243 GYECVCLAEYKGTHCEL 259
Score = 35.9 bits (79), Expect = 0.086
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 2/77 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 228 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 276
Query: 428 PDRNSWMNHTCDCPLGY 478
D +N TC C G+
Sbjct: 277 SD---GLNGTCICAPGF 290
Score = 30.3 bits (65), Expect = 4.3
Identities = 11/23 (47%), Positives = 15/23 (65%), Gaps = 2/23 (8%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYT 325
C NG +C ++ N CIC PG+T
Sbjct: 269 CLNGATCDSDGLNGTCICAPGFT 291
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1402
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
NS ++C C G++G C+ G
Sbjct: 1403 NS---YSCKCQPGFSGKRCETEQSTG 1425
Score = 55.6 bits (128), Expect = 1e-07
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 18/124 (14%)
Frame = +2
Query: 203 NIQECNT---YDRG---DIQASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIAS 355
NI EC++ ++G D A C C G C TE C P + CE ++
Sbjct: 1269 NINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1328
Query: 356 YLMSPPPP---------VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+L PP V+ C PC+NG TCK NS+ C C G+ G+ C++ +
Sbjct: 1329 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNIN 1385
Query: 509 LGQS 520
QS
Sbjct: 1386 ECQS 1389
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1250
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
++ C+CP GY G C+
Sbjct: 1251 GEFI---CECPSGYTGQRCE 1267
Score = 46.8 bits (106), Expect = 5e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1231 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1279
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N G C + + C C G+ G C+ + QS
Sbjct: 1280 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3479 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3520
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 3521 ---YQCDCPPGWTGSRC 3534
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3511 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3555
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 3556 HCLSSWTGHNC 3566
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESC-QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C Y S S +C + S + + + PP G + S + + C
Sbjct: 1143 CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV-----FHEC 1197
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1198 FFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1233
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3468 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3506
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1331 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1379
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
NS ++C C G++G C+ G
Sbjct: 1380 NS---YSCKCQPGFSGKRCETEQSTG 1402
Score = 55.6 bits (128), Expect = 1e-07
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 18/124 (14%)
Frame = +2
Query: 203 NIQECNT---YDRG---DIQASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIAS 355
NI EC++ ++G D A C C G C TE C P + CE ++
Sbjct: 1246 NINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1305
Query: 356 YLMSPPPP---------VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+L PP V+ C PC+NG TCK NS+ C C G+ G+ C++ +
Sbjct: 1306 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNIN 1362
Query: 509 LGQS 520
QS
Sbjct: 1363 ECQS 1366
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1227
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
++ C+CP GY G C+
Sbjct: 1228 GEFI---CECPSGYTGQRCE 1244
Score = 46.8 bits (106), Expect = 5e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1208 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1256
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N G C + + C C G+ G C+ + QS
Sbjct: 1257 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1290
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3453 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3494
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 3495 ---YQCDCPPGWTGSRC 3508
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3485 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3529
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 3530 HCLSSWTGHNC 3540
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESC-QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C Y S S +C + S + + + PP G + S + + C
Sbjct: 1120 CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV-----FHEC 1174
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1175 FFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1210
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3442 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3480
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1331 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1379
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
NS ++C C G++G C+ G
Sbjct: 1380 NS---YSCKCQPGFSGKRCETEQSTG 1402
Score = 55.6 bits (128), Expect = 1e-07
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 18/124 (14%)
Frame = +2
Query: 203 NIQECNT---YDRG---DIQASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIAS 355
NI EC++ ++G D A C C G C TE C P + CE ++
Sbjct: 1246 NINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1305
Query: 356 YLMSPPPP---------VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+L PP V+ C PC+NG TCK NS+ C C G+ G+ C++ +
Sbjct: 1306 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNIN 1362
Query: 509 LGQS 520
QS
Sbjct: 1363 ECQS 1366
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1227
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
++ C+CP GY G C+
Sbjct: 1228 GEFI---CECPSGYTGQRCE 1244
Score = 46.8 bits (106), Expect = 5e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1208 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1256
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N G C + + C C G+ G C+ + QS
Sbjct: 1257 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1290
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3453 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3494
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 3495 ---YQCDCPPGWTGSRC 3508
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3485 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3529
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 3530 HCLSSWTGHNC 3540
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESC-QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C Y S S +C + S + + + PP G + S + + C
Sbjct: 1120 CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV-----FHEC 1174
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1175 FFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1210
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3442 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3480
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1331 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1379
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
NS ++C C G++G C+ G
Sbjct: 1380 NS---YSCKCQPGFSGKRCETEQSTG 1402
Score = 55.6 bits (128), Expect = 1e-07
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 18/124 (14%)
Frame = +2
Query: 203 NIQECNT---YDRG---DIQASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIAS 355
NI EC++ ++G D A C C G C TE C P + CE ++
Sbjct: 1246 NINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1305
Query: 356 YLMSPPPP---------VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+L PP V+ C PC+NG TCK NS+ C C G+ G+ C++ +
Sbjct: 1306 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNIN 1362
Query: 509 LGQS 520
QS
Sbjct: 1363 ECQS 1366
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1227
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
++ C+CP GY G C+
Sbjct: 1228 GEFI---CECPSGYTGQRCE 1244
Score = 46.8 bits (106), Expect = 5e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1208 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1256
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N G C + + C C G+ G C+ + QS
Sbjct: 1257 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1290
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3453 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3494
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 3495 ---YQCDCPPGWTGSRC 3508
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3485 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3529
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 3530 HCLSSWTGHNC 3540
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESC-QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C Y S S +C + S + + + PP G + S + + C
Sbjct: 1120 CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV-----FHEC 1174
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1175 FFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1210
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3442 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3480
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
FLJ14964 fis, clone PLACE4000581, moderately similar to
FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1121 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1169
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
NS ++C C G++G C+ G
Sbjct: 1170 NS---YSCKCQPGFSGKRCETEQSTG 1192
Score = 55.6 bits (128), Expect = 1e-07
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 18/124 (14%)
Frame = +2
Query: 203 NIQECNT---YDRG---DIQASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIAS 355
NI EC++ ++G D A C C G C TE C P + CE ++
Sbjct: 1036 NINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1095
Query: 356 YLMSPPPP---------VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+L PP V+ C PC+NG TCK NS+ C C G+ G+ C++ +
Sbjct: 1096 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNIN 1152
Query: 509 LGQS 520
QS
Sbjct: 1153 ECQS 1156
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 969 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1017
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
++ C+CP GY G C+
Sbjct: 1018 GEFI---CECPSGYTGQRCE 1034
Score = 46.8 bits (106), Expect = 5e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 998 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1046
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N G C + + C C G+ G C+ + QS
Sbjct: 1047 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1080
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESC-QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C Y S S +C + S + + + PP G + S + + C
Sbjct: 910 CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV-----FHEC 964
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC N GTC+ + C CPLGY G C+ ++
Sbjct: 965 FFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1000
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 59.3 bits (137), Expect = 8e-09
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1402
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELG 514
NS ++C C G++G C+ G
Sbjct: 1403 NS---YSCKCQPGFSGKRCETEQSTG 1425
Score = 55.6 bits (128), Expect = 1e-07
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 18/124 (14%)
Frame = +2
Query: 203 NIQECNT---YDRG---DIQASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIAS 355
NI EC++ ++G D A C C G C TE C P + CE ++
Sbjct: 1269 NINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1328
Query: 356 YLMSPPPP---------VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+L PP V+ C PC+NG TCK NS+ C C G+ G+ C++ +
Sbjct: 1329 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNIN 1385
Query: 509 LGQS 520
QS
Sbjct: 1386 ECQS 1389
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1250
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
++ C+CP GY G C+
Sbjct: 1251 GEFI---CECPSGYTGQRCE 1267
Score = 46.8 bits (106), Expect = 5e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1231 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1279
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N G C + + C C G+ G C+ + QS
Sbjct: 1280 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3479 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3520
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 3521 ---YQCDCPPGWTGSRC 3534
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3511 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3555
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 3556 HCLSSWTGHNC 3566
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 1/99 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESC-QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C Y S S +C + S + + + PP G + S + + C
Sbjct: 1143 CPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQV-----FHEC 1197
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1198 FFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1233
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3468 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3506
>AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 58.8 bits (136), Expect = 1e-08
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 41 ESLRFETPMFVGGV-DDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDIN----SSIKSSN 205
+ L +T +FVGGV +D V V G GCI+ + +N+ +++ ++ + S
Sbjct: 1485 DGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSG 1544
Query: 206 IQECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN 385
+ EC + C+N +C CPPG G C +
Sbjct: 1545 VGECGDHPCLPNPCHGGAPCQN---LEAGRFHCQCPPGRVGPTCADE-----------KS 1590
Query: 386 PCSLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQ 496
PC +PC C+ P+ + C+CPLG G CQ
Sbjct: 1591 PCQPNPCHGAAPCRVLPEGGA----QCECPLGREGTFCQ 1625
Score = 44.8 bits (101), Expect = 2e-04
Identities = 20/47 (42%), Positives = 24/47 (51%)
Frame = +2
Query: 365 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+P P PC PC +GGTC+ D TC CP G GA C+ L
Sbjct: 1325 APQQPPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCEKVL 1370
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 2/104 (1%)
Frame = +2
Query: 35 PAESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSSNIQE 214
P L + P++VGG D + + A VS GF G I+ V L + + +
Sbjct: 1753 PHTVLNLKEPLYVGGAPDFSKLARA-AAVSSGFDGAIQLVSLGGRQLLTPEHVLRQ--VD 1809
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
++ + C NG SC C+CP G++G +CE
Sbjct: 1810 VTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
Score = 36.7 bits (81), Expect = 0.049
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +2
Query: 377 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
P S HPC NG +C P +++ C CP G++G C+ L
Sbjct: 1817 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGL 1856
Score = 34.3 bits (75), Expect = 0.26
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 7/87 (8%)
Frame = +2
Query: 254 SCQCEN----GGSCSTESTNCICPPGYTG---SYCETRIASYLMSPPPPVNPCSLHPCRN 412
+CQC GG+C + C C PG G CE ++ + C+ C
Sbjct: 792 ACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDP 851
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASC 493
G + D M C C G AG C
Sbjct: 852 QGAVRDDCEQ-MTGLCSCKPGVAGPKC 877
>AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein.
Length = 2026
Score = 58.8 bits (136), Expect = 1e-08
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 41 ESLRFETPMFVGGV-DDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDIN----SSIKSSN 205
+ L +T +FVGGV +D V V G GCI+ + +N+ +++ ++ + S
Sbjct: 1466 DGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSG 1525
Query: 206 IQECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN 385
+ EC + C+N +C CPPG G C +
Sbjct: 1526 VGECGDHPCLPNPCHGGAPCQN---LEAGRFHCQCPPGRVGPTCADE-----------KS 1571
Query: 386 PCSLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQ 496
PC +PC C+ P+ + C+CPLG G CQ
Sbjct: 1572 PCQPNPCHGAAPCRVLPEGGA----QCECPLGREGTFCQ 1606
Score = 44.8 bits (101), Expect = 2e-04
Identities = 20/47 (42%), Positives = 24/47 (51%)
Frame = +2
Query: 365 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+P P PC PC +GGTC+ D TC CP G GA C+ L
Sbjct: 1306 APQQPPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCEKVL 1351
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 2/104 (1%)
Frame = +2
Query: 35 PAESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSSNIQE 214
P L + P++VGG D + + A VS GF G I+ V L + + +
Sbjct: 1734 PHTVLNLKEPLYVGGAPDFSKLARA-AAVSSGFDGAIQLVSLGGRQLLTPEHVLRQ--VD 1790
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
++ + C NG SC C+CP G++G +CE
Sbjct: 1791 VTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1834
Score = 36.7 bits (81), Expect = 0.049
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +2
Query: 377 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
P S HPC NG +C P +++ C CP G++G C+ L
Sbjct: 1798 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGL 1837
Score = 34.3 bits (75), Expect = 0.26
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 7/87 (8%)
Frame = +2
Query: 254 SCQCEN----GGSCSTESTNCICPPGYTG---SYCETRIASYLMSPPPPVNPCSLHPCRN 412
+CQC GG+C + C C PG G CE ++ + C+ C
Sbjct: 773 ACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDP 832
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASC 493
G + D M C C G AG C
Sbjct: 833 QGAVRDDCEQ-MTGLCSCKPGVAGPKC 858
>AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 58.8 bits (136), Expect = 1e-08
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 41 ESLRFETPMFVGGV-DDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDIN----SSIKSSN 205
+ L +T +FVGGV +D V V G GCI+ + +N+ +++ ++ + S
Sbjct: 1485 DGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSG 1544
Query: 206 IQECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN 385
+ EC + C+N +C CPPG G C +
Sbjct: 1545 VGECGDHPCLPNPCHGGAPCQN---LEAGRFHCQCPPGRVGPTCADE-----------KS 1590
Query: 386 PCSLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQ 496
PC +PC C+ P+ + C+CPLG G CQ
Sbjct: 1591 PCQPNPCHGAAPCRVLPEGGA----QCECPLGREGTFCQ 1625
Score = 44.8 bits (101), Expect = 2e-04
Identities = 20/47 (42%), Positives = 24/47 (51%)
Frame = +2
Query: 365 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+P P PC PC +GGTC+ D TC CP G GA C+ L
Sbjct: 1325 APQQPPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCEKVL 1370
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 2/104 (1%)
Frame = +2
Query: 35 PAESLRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSSNIQE 214
P L + P++VGG D + + A VS GF G I+ V L + + +
Sbjct: 1753 PHTVLNLKEPLYVGGAPDFSKLARA-AAVSSGFDGAIQLVSLGGRQLLTPEHVLRQ--VD 1809
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
++ + C NG SC C+CP G++G +CE
Sbjct: 1810 VTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
Score = 36.7 bits (81), Expect = 0.049
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +2
Query: 377 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
P S HPC NG +C P +++ C CP G++G C+ L
Sbjct: 1817 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGL 1856
Score = 34.3 bits (75), Expect = 0.26
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 7/87 (8%)
Frame = +2
Query: 254 SCQCEN----GGSCSTESTNCICPPGYTG---SYCETRIASYLMSPPPPVNPCSLHPCRN 412
+CQC GG+C + C C PG G CE ++ + C+ C
Sbjct: 792 ACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDP 851
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASC 493
G + D M C C G AG C
Sbjct: 852 QGAVRDDCEQ-MTGLCSCKPGVAGPKC 877
>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosophila)
protein.
Length = 1523
Score = 58.0 bits (134), Expect = 2e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 254 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 970
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
+ +C CPLG+ G C++
Sbjct: 971 HLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 421
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1133
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQ 496
C + TC CP G+AG C+
Sbjct: 1134 CIVVQ---QEPTCRCPPGFAGPRCE 1155
Score = 51.6 bits (118), Expect = 2e-06
Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 6/151 (3%)
Frame = +2
Query: 59 TPMFVGGVDDSTVVVNPNAGVS---GGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYD 229
+P+++GG+ ST + G GGF GCI +V +N+ D + S
Sbjct: 1275 SPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQS--------- 1325
Query: 230 RGDIQASESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +SC C++G S +S C C PG+TG C+ +PC H
Sbjct: 1326 LGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGH 1375
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + G C S+M C C GY G C
Sbjct: 1376 RCHH-GKCVATGTSYM---CKCAEGYGGDLC 1402
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1045 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1093
Query: 437 NSWMNHTCDCPLGYAGASCQMP 502
N +TC CP G++G C+ P
Sbjct: 1094 N---GYTCTCPQGFSGPFCEHP 1112
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1001 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1051
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + +C+C GY+G C+
Sbjct: 1052 IPLDKGF---SCECVPGYSGKLCE 1072
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 918 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 956
Score = 34.7 bits (76), Expect = 0.20
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 260 QCENGGSCST--ESTNCICPPGYTGSYCETRI 349
+C+NG C + C CPPG+ G CE I
Sbjct: 1127 ECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 58.0 bits (134), Expect = 2e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 254 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 970
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
+ +C CPLG+ G C++
Sbjct: 971 HLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 421
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1133
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQ 496
C + TC CP G+AG C+
Sbjct: 1134 CIVVQ---QEPTCRCPPGFAGPRCE 1155
Score = 51.6 bits (118), Expect = 2e-06
Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 6/151 (3%)
Frame = +2
Query: 59 TPMFVGGVDDSTVVVNPNAGVS---GGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYD 229
+P+++GG+ ST + G GGF GCI +V +N+ D + S
Sbjct: 1275 SPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQS--------- 1325
Query: 230 RGDIQASESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +SC C++G S +S C C PG+TG C+ +PC H
Sbjct: 1326 LGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGH 1375
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + G C S+M C C GY G C
Sbjct: 1376 RCHH-GKCVATGTSYM---CKCAEGYGGDLC 1402
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1045 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1093
Query: 437 NSWMNHTCDCPLGYAGASCQMP 502
N +TC CP G++G C+ P
Sbjct: 1094 N---GYTCTCPQGFSGPFCEHP 1112
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1001 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1051
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + +C+C GY+G C+
Sbjct: 1052 IPLDKGF---SCECVPGYSGKLCE 1072
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 918 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 956
Score = 34.7 bits (76), Expect = 0.20
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 260 QCENGGSCST--ESTNCICPPGYTGSYCETRI 349
+C+NG C + C CPPG+ G CE I
Sbjct: 1127 ECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 58.0 bits (134), Expect = 2e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 254 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 349 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 397
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
+ +C CPLG+ G C++
Sbjct: 398 HLSDSHKDGFSCSCPLGFEGQRCEI 422
Score = 51.6 bits (118), Expect = 2e-06
Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 6/151 (3%)
Frame = +2
Query: 59 TPMFVGGVDDSTVVVNPNAGVS---GGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYD 229
+P+++GG+ ST + G GGF GCI +V +N+ D + S
Sbjct: 602 SPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQS--------- 652
Query: 230 RGDIQASESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +SC C++G S +S C C PG+TG C+ +PC H
Sbjct: 653 LGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGH 702
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + G C S+M C C GY G C
Sbjct: 703 RCHH-GKCVATGTSYM---CKCAEGYGGDLC 729
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 472 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 520
Query: 437 NSWMNHTCDCPLGYAGASCQMP 502
N +TC CP G++G C+ P
Sbjct: 521 N---GYTCTCPQGFSGPFCEHP 539
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 428 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 478
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + +C+C GY+G C+
Sbjct: 479 IPLDKGF---SCECVPGYSGKLCE 499
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 345 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 383
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 58.0 bits (134), Expect = 2e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 254 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 970
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
+ +C CPLG+ G C++
Sbjct: 971 HLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 421
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1133
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQ 496
C + TC CP G+AG C+
Sbjct: 1134 CIVVQ---QEPTCRCPPGFAGPRCE 1155
Score = 51.6 bits (118), Expect = 2e-06
Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 6/151 (3%)
Frame = +2
Query: 59 TPMFVGGVDDSTVVVNPNAGVS---GGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYD 229
+P+++GG+ ST + G GGF GCI +V +N+ D + S
Sbjct: 1275 SPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQS--------- 1325
Query: 230 RGDIQASESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +SC C++G S +S C C PG+TG C+ +PC H
Sbjct: 1326 LGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGH 1375
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + G C S+M C C GY G C
Sbjct: 1376 RCHH-GKCVATGTSYM---CKCAEGYGGDLC 1402
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1045 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1093
Query: 437 NSWMNHTCDCPLGYAGASCQMP 502
N +TC CP G++G C+ P
Sbjct: 1094 N---GYTCTCPQGFSGPFCEHP 1112
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1001 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1051
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + +C+C GY+G C+
Sbjct: 1052 IPLDKGF---SCECVPGYSGKLCE 1072
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 918 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 956
Score = 34.7 bits (76), Expect = 0.20
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 260 QCENGGSCST--ESTNCICPPGYTGSYCETRI 349
+C+NG C + C CPPG+ G CE I
Sbjct: 1127 ECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 58.0 bits (134), Expect = 2e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +2
Query: 254 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 958 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 1006
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQM 499
+ +C CPLG+ G C++
Sbjct: 1007 HLSDSHKDGFSCSCPLGFEGQRCEI 1031
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Frame = +2
Query: 260 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 421
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1118 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1169
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQ 496
C + TC CP G+AG C+
Sbjct: 1170 CIVVQ---QEPTCRCPPGFAGPRCE 1191
Score = 51.6 bits (118), Expect = 2e-06
Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 6/151 (3%)
Frame = +2
Query: 59 TPMFVGGVDDSTVVVNPNAGVS---GGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYD 229
+P+++GG+ ST + G GGF GCI +V +N+ D + S
Sbjct: 1311 SPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQS--------- 1361
Query: 230 RGDIQASESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +SC C++G S +S C C PG+TG C+ +PC H
Sbjct: 1362 LGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGH 1411
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + G C S+M C C GY G C
Sbjct: 1412 RCHH-GKCVATGTSYM---CKCAEGYGGDLC 1438
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1081 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1129
Query: 437 NSWMNHTCDCPLGYAGASCQMP 502
N +TC CP G++G C+ P
Sbjct: 1130 N---GYTCTCPQGFSGPFCEHP 1148
Score = 43.6 bits (98), Expect = 4e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1037 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1087
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQ 496
P + +C+C GY+G C+
Sbjct: 1088 IPLDKGF---SCECVPGYSGKLCE 1108
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 954 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 992
Score = 34.7 bits (76), Expect = 0.20
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +2
Query: 260 QCENGGSCST--ESTNCICPPGYTGSYCETRI 349
+C+NG C + C CPPG+ G CE I
Sbjct: 1163 ECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1194
>DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein.
Length = 231
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 1 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 49
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 50 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 82
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 51 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 99
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 100 DIGGDF---RCRCPAGFIDKTCSRPV 122
Score = 43.6 bits (98), Expect = 4e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 92 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 138
Query: 437 NSWMNHTCDCPLGYAGASC 493
++ +++ C C + G +C
Sbjct: 139 HTQVSYECLCKPEFTGLTC 157
Score = 31.9 bits (69), Expect = 1.4
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +2
Query: 254 SCQCENGGSC---STESTNCICPPGYTGSYC 337
S C+NGG+C + S C+C P +TG C
Sbjct: 127 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 157
>DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin
protein.
Length = 203
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 43.6 bits (98), Expect = 4e-04
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVC 185
>DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein.
Length = 212
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 50.0 bits (114), Expect = 5e-06
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASC 493
+ C CP G+ +C
Sbjct: 187 DIGGDF---RCRCPAGFIDKTC 205
>DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein.
Length = 315
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 53.6 bits (123), Expect = 4e-07
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ C CP G+ +C P++
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPVQ 210
>BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 4e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 437 NSWMNHTCDCPLGYAGASC 493
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 1.4
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +2
Query: 254 SCQCENGGSC---STESTNCICPPGYTGSYC 337
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 4e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 437 NSWMNHTCDCPLGYAGASC 493
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 1.4
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +2
Query: 254 SCQCENGGSC---STESTNCICPPGYTGSYC 337
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 56.8 bits (131), Expect = 4e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 4e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 437 NSWMNHTCDCPLGYAGASC 493
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 1.4
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +2
Query: 254 SCQCENGGSC---STESTNCICPPGYTGSYC 337
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 288
Score = 56.8 bits (131), Expect = 4e-08
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTCKPDR 436
C++G +C + CIC G+ G +C+ PC PCRNGG C+ D+
Sbjct: 2 CQHG-TCH-QPWQCICHSGWAGKFCDKGFHG--RDCERKAGPCEQAGSPCRNGGQCQDDQ 57
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+N TC C +G+ GA C++ ++
Sbjct: 58 GFALNFTCRCLVGFVGARCEVNVD 81
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 88 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 135
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP GY G +C++ L
Sbjct: 136 VH--DFDCLCPSGYGGKTCELVL 156
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 47 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 95
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N + +C CP G+AG C + L+
Sbjct: 96 DGINRF---SCLCPEGFAGRFCTINLD 119
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 126 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 162
>Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein
protein.
Length = 383
Score = 56.4 bits (130), Expect = 6e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 4e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 437 NSWMNHTCDCPLGYAGASC 493
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 1.4
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +2
Query: 254 SCQCENGGSC---STESTNCICPPGYTGSYC 337
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>U15981-1|AAA75365.1| 310|Homo sapiens dlk protein.
Length = 310
Score = 56.4 bits (130), Expect = 6e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 37.5 bits (83), Expect = 0.028
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
CEN G C+ + C CP G+ C PV C+ PC+NGGTC
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTC 223
>U15979-1|AAA75364.1| 382|Homo sapiens dlk protein.
Length = 382
Score = 56.4 bits (130), Expect = 6e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 400
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 88 DVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 136
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC++GGTC D + +C CP G++G C++
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 7e-07
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +2
Query: 263 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 4e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 437 NSWMNHTCDCPLGYAGASC 493
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 1.4
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +2
Query: 254 SCQCENGGSC---STESTNCICPPGYTGSYC 337
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 428 PDRNSWMNHTCDCPLGYAGASCQ 496
P + C CP + G CQ
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQ 765
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 4e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC+
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATCQ 822
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLEL 511
+S C CP GY G SCQ ++L
Sbjct: 823 ---DSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 52.8 bits (121), Expect = 7e-07
Identities = 29/93 (31%), Positives = 39/93 (41%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C G ++C C +G C S C+C G+TG CE + C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CI 696
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC P + + C CP GY G +C
Sbjct: 697 SAPCAHGGTCYPQPS---GYNCTCPTGYTGPTC 726
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 51.2 bits (117), Expect = 2e-06
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A S C NGGSC+ C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +2
Query: 254 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 428 PDRNSWM 448
+ ++
Sbjct: 947 AQPSGYL 953
Score = 46.8 bits (106), Expect = 5e-05
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Frame = +2
Query: 221 TYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPV 382
T +R Q + C C G C +++ C C PG+TG C+ R
Sbjct: 110 TGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------ 157
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 6e-04
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQRPCPRNSHCLQTG 863
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
S+ H C C G+ G C +PL
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPL 883
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 412
D+ A C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQRPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE 119
Score = 37.5 bits (83), Expect = 0.028
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 418
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 419 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 505
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.1 bits (77), Expect = 0.15
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 56.4 bits (130), Expect = 6e-08
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 292 QDGLDT---YTCLCPETWTGWDC 311
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 173
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 174 --TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 4e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 6e-04
Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
G +C ++ C CP G+ G+ + EL +
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGSQGRHWKELAE 632
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.005
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 411
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 412 LTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila)
protein.
Length = 1529
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 397
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1076 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1127
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+NG C N C C GY G C+
Sbjct: 1128 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCE 1157
Score = 50.8 bits (116), Expect = 3e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 975
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
C C G+ G +C++ ++
Sbjct: 976 EGEEDGFWCICADGFEGENCEVNVD 1000
Score = 46.8 bits (106), Expect = 5e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 958
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 998 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1048
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ C + CDC GY G C + +
Sbjct: 1049 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1078
Score = 46.0 bits (104), Expect = 8e-05
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = +2
Query: 44 SLRFETPMFVGGVDDSTVV--VNPNAGVSG-GFSGCIKDVVLNSNAVDINS-SIKSSNIQ 211
+L F++P++VGG+ + V + G +G F GCI+++ +NS D +++ +
Sbjct: 1272 TLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILP 1331
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C + + A +CQ S C C G+ G C+ R +PC
Sbjct: 1332 GCEPCHK-KVCAHGTCQ-----PSSQAGFTCECQEGWMGPLCDQRTN----------DPC 1375
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ C + GTC P N++ +++C C G+ G C
Sbjct: 1376 LGNKCVH-GTCLP-INAF-SYSCKCLEGHGGVLC 1406
Score = 32.7 bits (71), Expect = 0.80
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 9/55 (16%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIA-------SYLMSPPPPVNP 388
++ C+NG C C C PGY G CE ++ SYL P V P
Sbjct: 1126 DNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRP 1180
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 397
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1072 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1123
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+NG C N C C GY G C+
Sbjct: 1124 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCE 1153
Score = 50.8 bits (116), Expect = 3e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 923 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 971
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
C C G+ G +C++ ++
Sbjct: 972 EGEEDGFWCICADGFEGENCEVNVD 996
Score = 46.8 bits (106), Expect = 5e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 916 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 954
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 994 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1044
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ C + CDC GY G C + +
Sbjct: 1045 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1074
Score = 46.0 bits (104), Expect = 8e-05
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = +2
Query: 44 SLRFETPMFVGGVDDSTVV--VNPNAGVSG-GFSGCIKDVVLNSNAVDINS-SIKSSNIQ 211
+L F++P++VGG+ + V + G +G F GCI+++ +NS D +++ +
Sbjct: 1268 TLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILP 1327
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C + + A +CQ S C C G+ G C+ R +PC
Sbjct: 1328 GCEPCHK-KVCAHGTCQ-----PSSQAGFTCECQEGWMGPLCDQRTN----------DPC 1371
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ C + GTC P N++ +++C C G+ G C
Sbjct: 1372 LGNKCVH-GTCLP-INAF-SYSCKCLEGHGGVLC 1402
Score = 32.7 bits (71), Expect = 0.80
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 9/55 (16%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIA-------SYLMSPPPPVNP 388
++ C+NG C C C PGY G CE ++ SYL P V P
Sbjct: 1122 DNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRP 1176
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 397
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1068 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1119
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+NG C N C C GY G C+
Sbjct: 1120 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCE 1149
Score = 50.8 bits (116), Expect = 3e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 919 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 967
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
C C G+ G +C++ ++
Sbjct: 968 EGEEDGFWCICADGFEGENCEVNVD 992
Score = 46.8 bits (106), Expect = 5e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 912 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 950
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 990 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1040
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ C + CDC GY G C + +
Sbjct: 1041 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1070
Score = 46.0 bits (104), Expect = 8e-05
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = +2
Query: 44 SLRFETPMFVGGVDDSTVV--VNPNAGVSG-GFSGCIKDVVLNSNAVDINS-SIKSSNIQ 211
+L F++P++VGG+ + V + G +G F GCI+++ +NS D +++ +
Sbjct: 1264 TLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILP 1323
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C + + A +CQ S C C G+ G C+ R +PC
Sbjct: 1324 GCEPCHK-KVCAHGTCQ-----PSSQAGFTCECQEGWMGPLCDQRTN----------DPC 1367
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ C + GTC P N++ +++C C G+ G C
Sbjct: 1368 LGNKCVH-GTCLP-INAF-SYSCKCLEGHGGVLC 1398
Score = 32.7 bits (71), Expect = 0.80
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 9/55 (16%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIA-------SYLMSPPPPVNP 388
++ C+NG C C C PGY G CE ++ SYL P V P
Sbjct: 1118 DNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRP 1172
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 56.0 bits (129), Expect = 8e-08
Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 397
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1076 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1127
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+NG C N C C GY G C+
Sbjct: 1128 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCE 1157
Score = 50.8 bits (116), Expect = 3e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 975
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
C C G+ G +C++ ++
Sbjct: 976 EGEEDGFWCICADGFEGENCEVNVD 1000
Score = 46.8 bits (106), Expect = 5e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 958
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 998 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1048
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ C + CDC GY G C + +
Sbjct: 1049 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1078
Score = 46.0 bits (104), Expect = 8e-05
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = +2
Query: 44 SLRFETPMFVGGVDDSTVV--VNPNAGVSG-GFSGCIKDVVLNSNAVDINS-SIKSSNIQ 211
+L F++P++VGG+ + V + G +G F GCI+++ +NS D +++ +
Sbjct: 1272 TLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILP 1331
Query: 212 ECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C + + A +CQ S C C G+ G C+ R +PC
Sbjct: 1332 GCEPCHK-KVCAHGTCQ-----PSSQAGFTCECQEGWMGPLCDQRTN----------DPC 1375
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
+ C + GTC P N++ +++C C G+ G C
Sbjct: 1376 LGNKCVH-GTCLP-INAF-SYSCKCLEGHGGVLC 1406
Score = 32.7 bits (71), Expect = 0.80
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 9/55 (16%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIA-------SYLMSPPPPVNP 388
++ C+NG C C C PGY G CE ++ SYL P V P
Sbjct: 1126 DNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRP 1180
>BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 1009
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/106 (25%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVD-----INSSIKSSNIQ 211
+ F TP+++GG + +V G + GF GC++ + +N +D + ++ +++
Sbjct: 504 ITFRTPLYLGGAPSAYWLVRAT-GTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVG 562
Query: 212 ECNTYDRGDIQASESCQCENGGSCST---ESTNCICPPGYTGSYCE 340
EC++ + C +GG+C+ +S C+CP G+ G +CE
Sbjct: 563 ECSS------GICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCE 602
Score = 49.2 bits (112), Expect = 9e-06
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSS-NIQECNT 223
++ T +F+GGV + V N+GV FSG I+ ++LN + + S N++
Sbjct: 728 IKCNTDIFIGGVPNYDDV-KKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA-- 784
Query: 224 YDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSP 370
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 785 -----AHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 830
Score = 46.4 bits (105), Expect = 6e-05
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+PC PC +GG+C+P + + CDCPLG+ G CQ
Sbjct: 786 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQ 820
Score = 31.5 bits (68), Expect = 1.9
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C +GGTC + ++ C CPLG+ G C+
Sbjct: 569 CDEASCIHGGTCTAIKAD--SYICLCPLGFKGRHCE 602
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDL 340
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 830 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 884
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 931
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 932 PCPHGAQCQP 941
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 354
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 53.6 bits (123), Expect = 4e-07
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C C + +AG C++
Sbjct: 1317 NKFQ---CLCDVAFAGERCEV 1334
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDL 340
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 830 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 884
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 931
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 932 PCPHGAQCQP 941
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 354
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 707
Score = 31.1 bits (67), Expect = 2.4
Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIAS 355
DI S C NGG C C+C + G CE ++S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSS 1338
>AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 52.4 bits (120), Expect = 9e-07
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCP---LGYAGASCQMPL 505
N +TC CP GY GA C++ L
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDL 228
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 374
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 718 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 772
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 819
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 820 PCPHGAQCQP 829
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.5 bits (78), Expect = 0.11
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICP---PGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++ S C+N +C E CICP GYTG+ CE + N C+ +
Sbjct: 186 EVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDL-----------NECNSN 234
Query: 401 PCRNGGTC 424
PC++ G C
Sbjct: 235 PCQSNGEC 242
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 595
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
>AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDL 340
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 830 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 884
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 931
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 932 PCPHGAQCQP 941
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 354
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 52.4 bits (120), Expect = 9e-07
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCP---LGYAGASCQMPL 505
N +TC CP GY GA C++ L
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDL 228
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 374
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 718 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 772
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 819
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 820 PCPHGAQCQP 829
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.5 bits (78), Expect = 0.11
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICP---PGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++ S C+N +C E CICP GYTG+ CE + N C+ +
Sbjct: 186 EVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDL-----------NECNSN 234
Query: 401 PCRNGGTC 424
PC++ G C
Sbjct: 235 PCQSNGEC 242
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 595
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDL 340
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 830 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 884
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 931
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 932 PCPHGAQCQP 941
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 354
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
>AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 52.4 bits (120), Expect = 9e-07
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCP---LGYAGASCQMPL 505
N +TC CP GY GA C++ L
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDL 228
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 374
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 718 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 772
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 819
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 820 PCPHGAQCQP 829
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.5 bits (78), Expect = 0.11
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICP---PGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++ S C+N +C E CICP GYTG+ CE + N C+ +
Sbjct: 186 EVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDL-----------NECNSN 234
Query: 401 PCRNGGTC 424
PC++ G C
Sbjct: 235 PCQSNGEC 242
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 595
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
>AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDL 340
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 830 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 884
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 931
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 932 PCPHGAQCQP 941
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 354
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 707
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
>AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens
cDNA FLJ40230 fis, clone TESTI2022960, weakly similar to
Drosophila melanogaster SP2353 mRNA. ).
Length = 775
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/106 (25%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVD-----INSSIKSSNIQ 211
+ F TP+++GG + +V G + GF GC++ + +N +D + ++ +++
Sbjct: 270 ITFRTPLYLGGAPSAYWLVRAT-GTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVG 328
Query: 212 ECNTYDRGDIQASESCQCENGGSCST---ESTNCICPPGYTGSYCE 340
EC++ + C +GG+C+ +S C+CP G+ G +CE
Sbjct: 329 ECSS------GICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCE 368
Score = 49.2 bits (112), Expect = 9e-06
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSS-NIQECNT 223
++ T +F+GGV + V N+GV FSG I+ ++LN + + S N++
Sbjct: 494 IKCNTDIFIGGVPNYDDV-KKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA-- 550
Query: 224 YDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSP 370
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 551 -----AHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 596
Score = 46.4 bits (105), Expect = 6e-05
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+PC PC +GG+C+P + + CDCPLG+ G CQ
Sbjct: 552 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQ 586
Score = 31.5 bits (68), Expect = 1.9
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C +GGTC + ++ C CPLG+ G C+
Sbjct: 335 CDEASCIHGGTCTAIKAD--SYICLCPLGFKGRHCE 368
>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
(alternative protein) protein.
Length = 1294
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 54.8 bits (126), Expect = 2e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 52.4 bits (120), Expect = 9e-07
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCP---LGYAGASCQMPL 505
N +TC CP GY GA C++ L
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDL 228
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 374
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 718 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 772
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 773 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 819
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 820 PCPHGAQCQP 829
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.5 bits (78), Expect = 0.11
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICP---PGYTGSYCETRIASYLMSPPPPVNPCSLH 400
++ S C+N +C E CICP GYTG+ CE + N C+ +
Sbjct: 186 EVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDL-----------NECNSN 234
Query: 401 PCRNGGTC 424
PC++ G C
Sbjct: 235 PCQSNGEC 242
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 595
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 367
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 42 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 101
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 102 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 147
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 53.6 bits (123), Expect = 4e-07
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N + C C + +AG C++
Sbjct: 1317 NKFQ---CLCDVAFAGERCEV 1334
Score = 52.0 bits (119), Expect = 1e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDL 340
Score = 44.4 bits (100), Expect = 2e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 407 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLEL 511
N GTC P ++ +C CP GY G+ C++ L
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTL 486
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 406
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 41.9 bits (94), Expect = 0.001
Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Frame = +2
Query: 65 MFVGGVDDSTVVVNPNAGVSGGF-SGCIKDVVLNSNAVDI-----NSSIKSSNIQECNTY 226
+++GG+ D ++GGF GCI+DV LN+ ++ N++ + +
Sbjct: 830 IYIGGLPDKQ-----ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQG 884
Query: 227 DRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD + +S C NGG C + + +C CP +G CE V C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE------------EVQWCGFS 931
Query: 401 PCRNGGTCKP 430
PC +G C+P
Sbjct: 932 PCPHGAQCQP 941
Score = 40.7 bits (91), Expect = 0.003
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +2
Query: 275 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 448
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 449 NHTCDCPLGYAGASCQ 496
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 354
Score = 38.7 bits (86), Expect = 0.012
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.1 bits (77), Expect = 0.15
Identities = 13/35 (37%), Positives = 19/35 (54%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C PC++ G C N W+++ CDC Y G +C
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNC 707
Score = 31.1 bits (67), Expect = 2.4
Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIAS 355
DI S C NGG C C+C + G CE ++S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSS 1338
>AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isoform
II precursor variant protein.
Length = 441
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Frame = +2
Query: 161 NSNAVDINSSIKSSNIQECNTYDRGDIQASESC---QCENGGSC----STESTNCICPPG 319
NS D + S N D+ + C C+ +C S C CPPG
Sbjct: 67 NSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPG 126
Query: 320 YTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
Y+G+ CET I S C + C++GG C D + C CP GYAG C++
Sbjct: 127 YSGTICETTIGS-----------CGKNSCQHGGICHQDP---IYPVCICPAGYAGRFCEI 172
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 179 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 226
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N +TC CP Y+G +C++ ++
Sbjct: 227 --LNEIGRYTCICPHNYSGVNCELEID 251
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 144 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 192
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ ++C C GY G C + ++
Sbjct: 193 D---GYSCFCVPGYQGRHCDLEVD 213
Score = 47.2 bits (107), Expect = 3e-05
Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 296 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 342
Query: 434 RNSWMNHTCDCPLGYAGASCQMPL 505
+S N+TC C GY GA C++ L
Sbjct: 343 -DSVDNYTCHCWPGYTGAQCEIDL 365
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 249 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 297
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 505
+GG C N ++C+C G+ G C+ MPL
Sbjct: 298 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 329
Score = 39.1 bits (87), Expect = 0.009
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C N +C S ++ C C PGYTG+ CE +N C+ +PC++ G C
Sbjct: 335 CHNNATCEDSVDNYTCHCWPGYTGAQCEI-----------DLNECNSNPCQSNGEC 379
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
protein.
Length = 1095
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/73 (36%), Positives = 35/73 (47%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ GS C+ VNPC PC+NG TC + ++ C C GY
Sbjct: 8 CHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCMAQPSGYL---CQCAPGYD 53
Query: 482 GASCQMPLELGQS 520
G +C L+ QS
Sbjct: 54 GQNCSKELDACQS 66
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +2
Query: 233 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 97 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 145
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC +GGTC+ S + C CP G+ G +C
Sbjct: 146 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 176
Score = 53.2 bits (122), Expect = 5e-07
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 23 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 71
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
GTC P + H C CP G+ G C+
Sbjct: 72 HGTCTPKPGGF--H-CACPPGFVGLRCE 96
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 138 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 186
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C +GG C P C C GY G C P
Sbjct: 187 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 220
Score = 34.7 bits (76), Expect = 0.20
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 6/86 (6%)
Frame = +2
Query: 263 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 188 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 239
Query: 428 PDRN-SWMNHTCDCPLGYAGASCQMP 502
C CP G CQ P
Sbjct: 240 ETTGLGGPGFRCSCPHSSPGPRCQKP 265
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 55.2 bits (127), Expect = 1e-07
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGGT 421
++ C C G +C + C CPPG+TGS CE PP P C L C NGG+
Sbjct: 938 AQRCSCPPGAACHHVTGACRCPPGFTGSGCEQG------CPPGRYGPGCEQLCGCLNGGS 991
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
C + C CP G+ G C + G+
Sbjct: 992 CDAATGA-----CRCPTGFLGTDCNLTCPQGR 1018
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PCSLH- 400
+R + +C C NGG C + +C C G+TG +CE L PP C L
Sbjct: 1060 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAACHLEC 1113
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C N TC+P TC C G+ G +C+
Sbjct: 1114 SCHNNSTCEP-----ATGTCRCGPGFYGQACE 1140
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1027 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1081
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQ 517
N +C C LG+ G C++ G+
Sbjct: 1082 ----NGSCSCGLGWTGRHCELACPPGR 1104
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 436
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 422 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 473
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G +G +C+
Sbjct: 474 ---VTGACRCPPGVSGTNCE 490
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 2/90 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRN 412
+ +C C G +C + +C+CP G G C + P V H C N
Sbjct: 849 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCL------PRDVRAGCRHSGGCLN 902
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
GG C P C CP G+ G CQ P
Sbjct: 903 GGLCDPHTG-----RCLCPAGWTGDKCQSP 927
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +2
Query: 230 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 672 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 727
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
N G C P C C G+ G SCQ + G
Sbjct: 728 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 758
Score = 46.4 bits (105), Expect = 6e-05
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
+ CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 810 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA 865
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
+N +C CP G G C
Sbjct: 866 -----VNGSCLCPAGRRGPRC 881
Score = 46.4 bits (105), Expect = 6e-05
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETR---IASYLMSPPPPVNP-CSLH-PCRNGGT 421
C C N +C + C C PG+ G CE R L P C+LH C G
Sbjct: 1113 CSCHNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1172
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQM--PLELGQS 520
C P ++ C C GY G +C+ PL L ++
Sbjct: 1173 CDP-----VSGQCHCVDGYMGPTCREGGPLRLPEN 1202
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 424
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 504 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 557
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
D+ + +C C G+ G CQ ELG
Sbjct: 558 SCDKR---DGSCSCKAGFRGERCQAECELG 584
Score = 45.6 bits (103), Expect = 1e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCE 340
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 460 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 490
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 433
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 725 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 778
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
S + C C GY G C+ G
Sbjct: 779 AISGL---CLCEAGYVGPRCEQQCPQG 802
Score = 45.6 bits (103), Expect = 1e-04
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C+T G S C C G GSC S C+C GY G CE + P C
Sbjct: 755 CDTGHWGP-DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR-C 812
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C++G C ++ C CP G+ G C+
Sbjct: 813 Q---CQHGAAC-----DHVSGACTCPAGWRGTFCE 839
Score = 43.6 bits (98), Expect = 4e-04
Identities = 23/78 (29%), Positives = 32/78 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C NGG C + C+CP G+TG C++ CS C G C
Sbjct: 900 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG-EACAQRCS---CPPGAAC-----H 950
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP G+ G+ C+
Sbjct: 951 HVTGACRCPPGFTGSGCE 968
Score = 42.3 bits (95), Expect = 0.001
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
QEC G + S SC C G C + C CPPG TG CE +
Sbjct: 624 QECPVGTFG-VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGC 677
Query: 389 CSLHP-CRNGGTCKPDRNS------WMNHTCD--CPLGYAGASCQ 496
+ P C++ C P+ + ++ C CP G+ G SCQ
Sbjct: 678 QEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 722
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 55.2 bits (127), Expect = 1e-07
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGGT 421
++ C C G +C + C CPPG+TGS CE PP P C L C NGG+
Sbjct: 938 AQRCSCPPGAACHHVTGACRCPPGFTGSGCEQG------CPPGRYGPGCEQLCGCLNGGS 991
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
C + C CP G+ G C + G+
Sbjct: 992 CDAATGA-----CRCPTGFLGTDCNLTCPQGR 1018
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PCSLH- 400
+R + +C C NGG C + +C C G+TG +CE L PP C L
Sbjct: 1060 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAACHLEC 1113
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C N TC+P TC C G+ G +C+
Sbjct: 1114 SCHNNSTCEP-----ATGTCRCGPGFYGQACE 1140
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1027 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1081
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQ 517
N +C C LG+ G C++ G+
Sbjct: 1082 ----NGSCSCGLGWTGRHCELACPPGR 1104
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 436
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 422 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 473
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G +G +C+
Sbjct: 474 ---VTGACRCPPGVSGTNCE 490
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 2/90 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRN 412
+ +C C G +C + +C+CP G G C + P V H C N
Sbjct: 849 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCL------PRDVRAGCRHSGGCLN 902
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
GG C P C CP G+ G CQ P
Sbjct: 903 GGLCDPHTG-----RCLCPAGWTGDKCQSP 927
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +2
Query: 230 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 672 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 727
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
N G C P C C G+ G SCQ + G
Sbjct: 728 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 758
Score = 46.4 bits (105), Expect = 6e-05
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
+ CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 810 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA 865
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
+N +C CP G G C
Sbjct: 866 -----VNGSCLCPAGRRGPRC 881
Score = 46.4 bits (105), Expect = 6e-05
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETR---IASYLMSPPPPVNP-CSLH-PCRNGGT 421
C C N +C + C C PG+ G CE R L P C+LH C G
Sbjct: 1113 CSCHNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1172
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQM--PLELGQS 520
C P ++ C C GY G +C+ PL L ++
Sbjct: 1173 CDP-----VSGQCHCVDGYMGPTCREGGPLRLPEN 1202
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 424
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 504 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 557
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
D+ + +C C G+ G CQ ELG
Sbjct: 558 SCDKR---DGSCSCKAGFRGERCQAECELG 584
Score = 45.6 bits (103), Expect = 1e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCE 340
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 460 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 490
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 433
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 725 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 778
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
S + C C GY G C+ G
Sbjct: 779 AISGL---CLCEAGYVGPRCEQQCPQG 802
Score = 45.6 bits (103), Expect = 1e-04
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C+T G S C C G GSC S C+C GY G CE + P C
Sbjct: 755 CDTGHWGP-DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR-C 812
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C++G C ++ C CP G+ G C+
Sbjct: 813 Q---CQHGAAC-----DHVSGACTCPAGWRGTFCE 839
Score = 43.6 bits (98), Expect = 4e-04
Identities = 23/78 (29%), Positives = 32/78 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C NGG C + C+CP G+TG C++ CS C G C
Sbjct: 900 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG-EACAQRCS---CPPGAAC-----H 950
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP G+ G+ C+
Sbjct: 951 HVTGACRCPPGFTGSGCE 968
Score = 42.3 bits (95), Expect = 0.001
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
QEC G + S SC C G C + C CPPG TG CE +
Sbjct: 624 QECPVGTFG-VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGC 677
Query: 389 CSLHP-CRNGGTCKPDRNS------WMNHTCD--CPLGYAGASCQ 496
+ P C++ C P+ + ++ C CP G+ G SCQ
Sbjct: 678 QEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 722
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 54.8 bits (126), Expect = 2e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 281 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPP-------H-CRNGGTC- 331
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
+NS + C C G+ G SC+ L+
Sbjct: 332 --QNSAGSFHCVCVSGWGGTSCEENLD 356
Score = 53.6 bits (123), Expect = 4e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 263 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 400 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 451
Query: 431 DRNSWMNHTCDCPLGYAGASCQ 496
N+ + C CP GY G+ C+
Sbjct: 452 -LNTPGSFNCLCPPGYTGSRCE 472
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 430
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 204 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 252
Query: 431 DRNSWMNHTCDCPLGYAGASCQM 499
+++S H C CP G+ G C++
Sbjct: 253 EKDSTF-HLCLCPPGFIGPGCEV 274
Score = 51.2 bits (117), Expect = 2e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Frame = +2
Query: 263 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 242 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVN----------PDN-CVSHQCQNGGTC 290
Query: 425 KPDRNSWMNHTCDCPLGYAGASC 493
+ ++ +TC CP + G C
Sbjct: 291 QDGLDT---YTCLCPETWTGWDC 310
Score = 51.2 bits (117), Expect = 2e-06
Identities = 27/56 (48%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 445 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC 489
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C +++ C C PG+TG C+ R + CS +PC NGG C
Sbjct: 126 CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR------------DFCSANPCVNGGVCLA- 172
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
++ C CP G+ G +C+
Sbjct: 173 --TYPQIQCHCPPGFEGHACE 191
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 164 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 211
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
N+ + C CP+G G C++
Sbjct: 212 NTLGSFQCLCPVGQEGPRCEL 232
Score = 41.1 bits (92), Expect = 0.002
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
D + +A C NGG+C S S +C+C G+ G+ CE + + C
Sbjct: 313 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAA 361
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G TC DR + +C CP G G C +
Sbjct: 362 TCAPGSTC-IDRVG--SFSCLCPPGRTGLLCHL 391
Score = 38.7 bits (86), Expect = 0.012
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +2
Query: 230 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 23 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 72
Query: 401 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 508
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 73 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 118
Score = 37.1 bits (82), Expect = 0.037
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C G +C S +C+CPPG TG C + C PC C +
Sbjct: 363 CAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DMCLSQPCHGDAQCSTNP 410
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
+ C C GY+G +C L+
Sbjct: 411 LTGST-LCLCQPGYSGPTCHQDLD 433
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +2
Query: 263 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 73 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 122
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
C G C + C C G+ G CQ+
Sbjct: 123 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 155
>X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA for
the chondroitin sulphate proteoglycan versican, V1
splice-variant; precursor peptide. ).
Length = 2409
Score = 54.4 bits (125), Expect = 2e-07
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 2/117 (1%)
Frame = +2
Query: 164 SNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYC 337
SN D I +++ Y G + + C NGG+C T+ C C PGY+G C
Sbjct: 2079 SNETDFLIGINEESVEGTAIYLPGPDRCKMN-PCLNGGTCYPTETSYVCTCVPGYSGDQC 2137
Query: 338 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
E + C +PCRNG TC N++ C C Y GA C+ E
Sbjct: 2138 EL-----------DFDECHSNPCRNGATCVDGFNTF---RCLCLPSYVGALCEQDTE 2180
>U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate
proteoglycan versican V0 splice-variant precursor peptide
protein.
Length = 3396
Score = 54.4 bits (125), Expect = 2e-07
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 2/117 (1%)
Frame = +2
Query: 164 SNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYC 337
SN D I +++ Y G + + C NGG+C T+ C C PGY+G C
Sbjct: 3066 SNETDFLIGINEESVEGTAIYLPGPDRCKMN-PCLNGGTCYPTETSYVCTCVPGYSGDQC 3124
Query: 338 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
E + C +PCRNG TC N++ C C Y GA C+ E
Sbjct: 3125 EL-----------DFDECHSNPCRNGATCVDGFNTF---RCLCLPSYVGALCEQDTE 3167
>J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroitin
sulfate proteoglycan core protein mRNA, 3' end. ).
Length = 688
Score = 54.4 bits (125), Expect = 2e-07
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 2/117 (1%)
Frame = +2
Query: 164 SNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYC 337
SN D I +++ Y G + + C NGG+C T+ C C PGY+G C
Sbjct: 358 SNETDFLIGINEESVEGTAIYLPGPDRCKMN-PCLNGGTCYPTETSYVCTCVPGYSGDQC 416
Query: 338 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
E + C +PCRNG TC N++ C C Y GA C+ E
Sbjct: 417 EL-----------DFDECHSNPCRNGATCVDGFNTF---RCLCLPSYVGALCEQDTE 459
>BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein
protein.
Length = 2060
Score = 54.4 bits (125), Expect = 2e-07
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 2/117 (1%)
Frame = +2
Query: 164 SNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYC 337
SN D I +++ Y G + + C NGG+C T+ C C PGY+G C
Sbjct: 1730 SNETDFLIGINEESVEGTAIYLPGPDRCKMN-PCLNGGTCYPTETSYVCTCVPGYSGDQC 1788
Query: 338 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
E + C +PCRNG TC N++ C C Y GA C+ E
Sbjct: 1789 EL-----------DFDECHSNPCRNGATCVDGFNTF---RCLCLPSYVGALCEQDTE 1831
>BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophila)
protein.
Length = 618
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSC-----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + C CPPG+ GS CE R V+ CSL PCRNGG C
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR-----------VDRCSLQPCRNGGLCL 369
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
D + C C G+AG C+ L+
Sbjct: 370 -DLGHALR--CRCRAGFAGPRCEHDLD 393
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSCS S C CP G+ G CE + C+ PC NGG C
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVT-----------CADGPCFNGGLCVGGA 331
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + C CP G+ G++C+
Sbjct: 332 DPDSAYICHCPPGFQGSNCE 351
Score = 46.0 bits (104), Expect = 8e-05
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C + C C G+ G C R +PC+ PC +GG C
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRER-----------ADPCAARPCAHGGRCYA-- 446
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C C GY GA C+ P+
Sbjct: 447 -HFSGLVCACAPGYMGARCEFPV 468
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIA-SYLMSPPPPVN-----------PCSLH 400
C E+G C + C C G+TG C ++ S +SP P + PC +
Sbjct: 224 CSPEHG-FCE-QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGN 281
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC NGG+C S+ C CP G+ G C++
Sbjct: 282 PCANGGSCSETPRSF---ECTCPRGFYGLRCEV 311
Score = 44.4 bits (100), Expect = 2e-04
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C C G+ G CE + + C+ C NGGTC
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-----------DDCAGRACANGGTCVEGG 410
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ H C C LG+ G C+
Sbjct: 411 GA---HRCSCALGFGGRDCR 427
Score = 35.1 bits (77), Expect = 0.15
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRI----ASYLMSPPPPVNP 388
C +GG C + C C PGY G+ CE + AS L + PP + P
Sbjct: 438 CAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLRP 485
>AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens
cDNA FLJ90821 fis, clone Y79AA1001328, highly similar to
Delta-like protein 3 precursor. ).
Length = 587
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSC-----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + C CPPG+ GS CE R V+ CSL PCRNGG C
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR-----------VDRCSLQPCRNGGLCL 369
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
D + C C G+AG C+ L+
Sbjct: 370 -DLGHALR--CRCRAGFAGPRCEHDLD 393
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSCS S C CP G+ G CE + C+ PC NGG C
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVT-----------CANGPCFNGGLCVGGA 331
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + C CP G+ G++C+
Sbjct: 332 DPDSAYICHCPPGFQGSNCE 351
Score = 46.8 bits (106), Expect = 5e-05
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C + C C G+ G C R +PC++ PC +GG C
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRER-----------ADPCAVRPCAHGGRCYA-- 446
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C C GY GA C+ P+
Sbjct: 447 -HFSGLVCACAPGYMGARCEFPV 468
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIA-SYLMSPPPPVN-----------PCSLH 400
C E+G C + C C G+TG C ++ S +SP P + PC +
Sbjct: 224 CSPEHG-FCE-QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGN 281
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC NGG+C S+ C CP G+ G C++
Sbjct: 282 PCANGGSCSETPRSF---ECTCPRGFYGLRCEV 311
Score = 44.4 bits (100), Expect = 2e-04
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C C G+ G CE + + C+ C NGGTC
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-----------DDCAGRACANGGTCVEGG 410
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ H C C LG+ G C+
Sbjct: 411 GA---HRCSCALGFGGRDCR 427
>AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor
protein.
Length = 618
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSC-----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C NGG C + C CPPG+ GS CE R V+ CSL PCRNGG C
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR-----------VDRCSLQPCRNGGLCL 369
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
D + C C G+AG C+ L+
Sbjct: 370 -DLGHALR--CRCRAGFAGPRCEHDLD 393
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSCS S C CP G+ G CE + C+ PC NGG C
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVT-----------CADGPCFNGGLCVGGA 331
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ + C CP G+ G++C+
Sbjct: 332 DPDSAYICHCPPGFQGSNCE 351
Score = 46.0 bits (104), Expect = 8e-05
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C + C C G+ G C R +PC+ PC +GG C
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRER-----------ADPCAARPCAHGGRCYA-- 446
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C C GY GA C+ P+
Sbjct: 447 -HFSGLVCACAPGYMGARCEFPV 468
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIA-SYLMSPPPPVN-----------PCSLH 400
C E+G C + C C G+TG C ++ S +SP P + PC +
Sbjct: 224 CSPEHG-FCE-QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGN 281
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
PC NGG+C S+ C CP G+ G C++
Sbjct: 282 PCANGGSCSETPRSF---ECTCPRGFYGLRCEV 311
Score = 44.4 bits (100), Expect = 2e-04
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG C + C C G+ G CE + + C+ C NGGTC
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-----------DDCAGRACANGGTCVEGG 410
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ H C C LG+ G C+
Sbjct: 411 GA---HRCSCALGFGGRDCR 427
Score = 35.1 bits (77), Expect = 0.15
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRI----ASYLMSPPPPVNP 388
C +GG C + C C PGY G+ CE + AS L + PP + P
Sbjct: 438 CAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLRP 485
>AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate
proteoglycan 2 (versican) variant protein.
Length = 3410
Score = 54.4 bits (125), Expect = 2e-07
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 2/117 (1%)
Frame = +2
Query: 164 SNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYC 337
SN D I +++ Y G + + C NGG+C T+ C C PGY+G C
Sbjct: 3080 SNETDFLIGINEESVEGTAIYLPGPDRCKMN-PCLNGGTCYPTETSYVCTCVPGYSGDQC 3138
Query: 338 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
E + C +PCRNG TC N++ C C Y GA C+ E
Sbjct: 3139 EL-----------DFDECHSNPCRNGATCVDGFNTF---RCLCLPSYVGALCEQDTE 3181
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 3e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 496
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 482 GASCQ 496
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 41.9 bits (94), Expect = 0.001
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 395 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPLE 508
P GG P S+ + C CP G+ GA C + ++
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Score = 41.1 bits (92), Expect = 0.002
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +2
Query: 242 QASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ S + C +G C + + NC C G G C+ P PC +PC NG
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-----------PTLPCEANPCLNG 1185
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQM 499
GTC R + C C ++G C++
Sbjct: 1186 GTC---RAAGGVSECICNARFSGQFCEV 1210
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +2
Query: 302 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 479 AGASCQMPLE 508
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 39.9 bits (89), Expect = 0.005
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCARG-RCHTHP 1112
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ G C++P+
Sbjct: 1113 DG--RFECRCPPGFGGPRCRLPV 1133
Score = 38.7 bits (86), Expect = 0.012
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 38.3 bits (85), Expect = 0.016
Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 4/92 (4%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PC 406
+ S C G C T C CPPG+ G C P P CSL+ C
Sbjct: 1095 VDPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRL---------PVPSKECSLNVTC 1144
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
+G C+ + C C G AG CQ+P
Sbjct: 1145 LDGSPCEGGSPA---ANCSCLEGLAGQRCQVP 1173
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES--TNCICPPGYTGSYCETRIASYLMSPPP 376
E+ C NGG+C + CIC ++G +CE +A L P P
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE--VAKGLPLPLP 1219
Score = 31.1 bits (67), Expect = 2.4
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Frame = +2
Query: 125 GGFSGCIKDVVLNSN-----AVDINSSIKSSNIQECNTYD-RGDIQASESCQ---CENGG 277
G F GC++D+ L+ + +++S + S + +++ + + C C NGG
Sbjct: 761 GPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGG 820
Query: 278 SC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 424
+C + +C CP +TG C A L P P + P + +G C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 3e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 496
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 482 GASCQ 496
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 41.9 bits (94), Expect = 0.001
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 395 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPLE 508
P GG P S+ + C CP G+ GA C + ++
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Score = 41.1 bits (92), Expect = 0.002
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +2
Query: 242 QASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ S + C +G C + + NC C G G C+ P PC +PC NG
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-----------PTLPCEANPCLNG 1185
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQM 499
GTC R + C C ++G C++
Sbjct: 1186 GTC---RAAGGVSECICNARFSGQFCEV 1210
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +2
Query: 302 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 479 AGASCQMPLE 508
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 39.9 bits (89), Expect = 0.005
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCARG-RCHTHP 1112
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ G C++P+
Sbjct: 1113 DG--RFECRCPPGFGGPRCRLPV 1133
Score = 38.7 bits (86), Expect = 0.012
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 38.3 bits (85), Expect = 0.016
Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 4/92 (4%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PC 406
+ S C G C T C CPPG+ G C P P CSL+ C
Sbjct: 1095 VDPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRL---------PVPSKECSLNVTC 1144
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
+G C+ + C C G AG CQ+P
Sbjct: 1145 LDGSPCEGGSPA---ANCSCLEGLAGQRCQVP 1173
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES--TNCICPPGYTGSYCETRIASYLMSPPP 376
E+ C NGG+C + CIC ++G +CE +A L P P
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE--VAKGLPLPLP 1219
Score = 31.1 bits (67), Expect = 2.4
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Frame = +2
Query: 125 GGFSGCIKDVVLNSN-----AVDINSSIKSSNIQECNTYD-RGDIQASESCQ---CENGG 277
G F GC++D+ L+ + +++S + S + +++ + + C C NGG
Sbjct: 761 GPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGG 820
Query: 278 SC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 424
+C + +C CP +TG C A L P P + P + +G C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 3e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 496
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 482 GASCQ 496
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 41.9 bits (94), Expect = 0.001
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 395 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPLE 508
P GG P S+ + C CP G+ GA C + ++
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +2
Query: 302 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 479 AGASCQMPLE 508
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 38.7 bits (86), Expect = 0.012
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 35.9 bits (79), Expect = 0.086
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCAR-GRCHTHP 1112
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G+ G C+
Sbjct: 1113 DG--RFECRCPPGFGGPRCR 1130
Score = 31.1 bits (67), Expect = 2.4
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Frame = +2
Query: 125 GGFSGCIKDVVLNSN-----AVDINSSIKSSNIQECNTYD-RGDIQASESCQ---CENGG 277
G F GC++D+ L+ + +++S + S + +++ + + C C NGG
Sbjct: 761 GPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGG 820
Query: 278 SC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 424
+C + +C CP +TG C A L P P + P + +G C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 3e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 496
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 482 GASCQ 496
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 41.9 bits (94), Expect = 0.001
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 395 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPLE 508
P GG P S+ + C CP G+ GA C + ++
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Score = 41.1 bits (92), Expect = 0.002
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +2
Query: 242 QASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
+ S + C +G C + + NC C G G C+ P PC +PC NG
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-----------PTLPCEANPCLNG 1185
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQM 499
GTC R + C C ++G C++
Sbjct: 1186 GTC---RAAGGVSECICNARFSGQFCEV 1210
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +2
Query: 302 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 479 AGASCQMPLE 508
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 39.9 bits (89), Expect = 0.005
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCARG-RCHTHP 1112
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ C CP G+ G C++P+
Sbjct: 1113 DG--RFECRCPPGFGGPRCRLPV 1133
Score = 38.7 bits (86), Expect = 0.012
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 38.3 bits (85), Expect = 0.016
Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 4/92 (4%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PC 406
+ S C G C T C CPPG+ G C P P CSL+ C
Sbjct: 1095 VDPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRL---------PVPSKECSLNVTC 1144
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
+G C+ + C C G AG CQ+P
Sbjct: 1145 LDGSPCEGGSPA---ANCSCLEGLAGQRCQVP 1173
Score = 31.5 bits (68), Expect = 1.9
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES--TNCICPPGYTGSYCETRIASYLMSPPP 376
E+ C NGG+C + CIC ++G +CE +A L P P
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE--VAKGLPLPLP 1219
Score = 31.1 bits (67), Expect = 2.4
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Frame = +2
Query: 125 GGFSGCIKDVVLNSN-----AVDINSSIKSSNIQECNTYD-RGDIQASESCQ---CENGG 277
G F GC++D+ L+ + +++S + S + +++ + + C C NGG
Sbjct: 761 GPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGG 820
Query: 278 SC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 424
+C + +C CP +TG C A L P P + P + +G C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 54.0 bits (124), Expect = 3e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 3e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 3e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 496
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 482 GASCQ 496
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 41.9 bits (94), Expect = 0.001
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 395 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPLE 508
P GG P S+ + C CP G+ GA C + ++
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Score = 40.3 bits (90), Expect = 0.004
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +2
Query: 302 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 479 AGASCQMPLE 508
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 38.7 bits (86), Expect = 0.012
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 35.9 bits (79), Expect = 0.086
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCAR-GRCHTHP 1112
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G+ G C+
Sbjct: 1113 DG--RFECRCPPGFGGPRCR 1130
Score = 31.1 bits (67), Expect = 2.4
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Frame = +2
Query: 125 GGFSGCIKDVVLNSN-----AVDINSSIKSSNIQECNTYD-RGDIQASESCQ---CENGG 277
G F GC++D+ L+ + +++S + S + +++ + + C C NGG
Sbjct: 761 GPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGG 820
Query: 278 SC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 424
+C + +C CP +TG C A L P P + P + +G C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 54.0 bits (124), Expect = 3e-07
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PCSLH- 400
+R + +C C NGG C + +C C G+TG +CE L PP C L
Sbjct: 1077 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAACHLEC 1130
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C N TC+P TC C G+ G +C+
Sbjct: 1131 SCHNNSTCEP-----ATGTCRCGPGFYGQACE 1157
Score = 52.8 bits (121), Expect = 7e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGGT 421
++ C C +C + C CPPG+TGS CE PP P C L C NGG+
Sbjct: 955 AQRCSCPPAAACHHVTGACRCPPGFTGSGCEQG------CPPGRYGPGCEQLCGCLNGGS 1008
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 517
C + C CP G+ G C + G+
Sbjct: 1009 CDAATGA-----CRCPTGFLGTDCNLTCPQGR 1035
Score = 52.4 bits (120), Expect = 9e-07
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1044 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1098
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQ 517
N +C C LG+ G C++ G+
Sbjct: 1099 ----NGSCSCGLGWTGRHCELACPPGR 1121
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 436
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 439 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 490
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G +G +C+
Sbjct: 491 ---VTGACRCPPGVSGTNCE 507
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 2/90 (2%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRN 412
+ +C C G +C + +C+CP G G C + P V H C N
Sbjct: 866 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCL------PRDVRAGCRHSGGCLN 919
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
GG C P C CP G+ G CQ P
Sbjct: 920 GGLCDPHTG-----RCLCPAGWTGDKCQSP 944
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +2
Query: 230 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 689 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 744
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
N G C P C C G+ G SCQ + G
Sbjct: 745 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 775
Score = 46.4 bits (105), Expect = 6e-05
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 391
C+T G S C C G GSC S C+C GY G CE + P
Sbjct: 772 CDTGHWGP-DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE---- 826
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
L C++G C ++ C CP G+ G C+
Sbjct: 827 QLCQCQHGAAC-----DHVSGACTCPAGWRGTFCE 856
Score = 46.4 bits (105), Expect = 6e-05
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETR---IASYLMSPPPPVNP-CSLH-PCRNGGT 421
C C N +C + C C PG+ G CE R L P C+LH C G
Sbjct: 1130 CSCHNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1189
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQM--PLELGQS 520
C P ++ C C GY G +C+ PL L ++
Sbjct: 1190 CDP-----VSGQCHCVDGYMGPTCREGGPLRLPEN 1219
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 424
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 521 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 574
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
D+ + +C C G+ G CQ ELG
Sbjct: 575 SCDKR---DGSCSCKAGFRGERCQAECELG 601
Score = 46.0 bits (104), Expect = 8e-05
Identities = 24/79 (30%), Positives = 35/79 (44%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 829 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA-- 882
Query: 437 NSWMNHTCDCPLGYAGASC 493
+N +C CP G G C
Sbjct: 883 ---VNGSCLCPAGRRGPRC 898
Score = 45.6 bits (103), Expect = 1e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCE 340
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 477 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 507
Score = 45.6 bits (103), Expect = 1e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 433
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 742 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 795
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELG 514
S + C C GY G C+ G
Sbjct: 796 AISGL---CLCEAGYVGPRCEQQCPQG 819
Score = 42.3 bits (95), Expect = 0.001
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
QEC G + S SC C G C + C CPPG TG CE +
Sbjct: 641 QECPVGTFG-VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGC 694
Query: 389 CSLHP-CRNGGTCKPDRNS------WMNHTCD--CPLGYAGASCQ 496
+ P C++ C P+ + ++ C CP G+ G SCQ
Sbjct: 695 QEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 739
Score = 42.3 bits (95), Expect = 0.001
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN- 439
C NGG C + C+CP G+TG C++ P + C +C P
Sbjct: 917 CLNGGLCDPHTGRCLCPAGWTGDKCQS----------PCLRGWFGEACAQRCSCPPAAAC 966
Query: 440 SWMNHTCDCPLGYAGASCQ 496
+ C CP G+ G+ C+
Sbjct: 967 HHVTGACRCPPGFTGSGCE 985
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 453 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDECASSPCHSGGLCEDL 501
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
+ + H C CP G++G C++ ++L
Sbjct: 502 ADGF--H-CHCPQGFSGPLCEVDVDL 524
Score = 50.8 bits (116), Expect = 3e-06
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 301 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 349
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+ + C CP G++G +C
Sbjct: 350 PSGF---ECHCPSGWSGPTC 366
Score = 50.8 bits (116), Expect = 3e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 745 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 792
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
+W C+C G+AG C++ ++ QS
Sbjct: 793 VNWFR--CECAPGFAGPDCRINIDECQS 818
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S ++ C CPPG+ GS C S C +PC NGGTC
Sbjct: 706 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------SCLPNPCVNGGTCV--- 752
Query: 437 NSWMNHTCDCPLGYAGASC 493
S + +C C G+ G +C
Sbjct: 753 GSGASFSCICRDGWEGRTC 771
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 489 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 536
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++ C CP + G +C +P E
Sbjct: 537 --YNLEGDYYCACPDDFGGKNCSVPRE 561
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A S C NGGSC + C CP G++G C + ++ C+ +PC GG
Sbjct: 334 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASA----------DIDECASNPCAAGG 383
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQM 499
TC + + C CP + GA+CQ+
Sbjct: 384 TCVDQVDGF---ECICPEQWVGATCQL 407
Score = 48.0 bits (109), Expect = 2e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 591 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 639
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G C
Sbjct: 640 VDAF---RCFCPSGWEGELC 656
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 783 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 830
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N + C CP G AG CQ + G+S
Sbjct: 831 INGYR---CSCPPGRAGPRCQEVIGFGRS 856
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C GG+C + CICP + G+ C+ N C PC
Sbjct: 370 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DANECEGKPCL 418
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N +CK N + CDC G+ G +C +
Sbjct: 419 NAFSCK---NLIGGYYCDCIPGWKGINCHI 445
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 616 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 664
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC + G C N + C C G+ G +C
Sbjct: 665 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 694
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 442
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 269 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 314
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP GY+G +C+
Sbjct: 315 ---YRCTCPDGYSGRNCE 329
Score = 37.5 bits (83), Expect = 0.028
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G C C C G+ G C +R C + C NGGTC
Sbjct: 668 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-----------CDAYTCSNGGTCYDSG 716
Query: 437 NSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G++C
Sbjct: 717 DTF---RCACPPGWKGSTC 732
>BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein.
Length = 600
Score = 52.8 bits (121), Expect = 7e-07
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ A +S C++GG C + C+CP + G +CET +PC PC
Sbjct: 64 EVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCET-----------VSDPCFSSPCG 112
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
G C S H+C C +GY G C L
Sbjct: 113 GRGYCLASNGS---HSCTCKVGYTGEDCAKEL 141
Score = 49.6 bits (113), Expect = 7e-06
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGGSC + C CP G+ G +CET V+ C PC++GG C+
Sbjct: 35 CRNGGSCRNLPGAYVCRCPAGFVGVHCETE-----------VDACDSSPCQHGGRCESGG 83
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+++ C CP + G C+
Sbjct: 84 GAYL---CVCPESFFGYHCE 100
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 513 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 546
Score = 44.0 bits (99), Expect = 3e-04
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C HPCRNGG+C RN + C CP G+ G C+ ++
Sbjct: 30 CRAHPCRNGGSC---RNLPGAYVCRCPAGFVGVHCETEVD 66
Score = 33.9 bits (74), Expect = 0.35
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 518 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKSFPVWEGGVC 573
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDECASSPCHSGGLCEDL 516
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 3e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S ++ C CPPG+ GS C S C +PC NGGTC
Sbjct: 721 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------SCLPNPCVNGGTCV--- 767
Query: 437 NSWMNHTCDCPLGYAGASC 493
S + +C C G+ G +C
Sbjct: 768 GSGASFSCICRDGWEGRTC 786
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQM 499
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 2e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N + C CP G AG CQ + G+S
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRS 871
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C GG+C + CICP + G+ C+ N C PC
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DANECEGKPCL 433
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N +CK N + CDC G+ G +C +
Sbjct: 434 NAFSCK---NLIGGYYCDCIPGWKGINCHI 460
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 442
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 37.5 bits (83), Expect = 0.028
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G C C C G+ G C +R C + C NGGTC
Sbjct: 683 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-----------CDAYTCSNGGTCYDSG 731
Query: 437 NSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G++C
Sbjct: 732 DTF---RCACPPGWKGSTC 747
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 430 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 478
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
+ + H C CP G++G C++ ++L
Sbjct: 479 ADGF--H-CHCPQGFSGPLCEVDVDL 501
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 3e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 769
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
+W C+C G+AG C++ ++ QS
Sbjct: 770 VNWFR--CECAPGFAGPDCRINIDECQS 795
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S ++ C CPPG+ GS C S C +PC NGGTC
Sbjct: 683 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------SCLPNPCVNGGTCV--- 729
Query: 437 NSWMNHTCDCPLGYAGASC 493
S + +C C G+ G +C
Sbjct: 730 GSGASFSCICRDGWEGRTC 748
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 466 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 513
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++ C CP + G +C +P E
Sbjct: 514 --YNLEGDYYCACPDDFGGKNCSVPRE 538
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQM 499
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 2e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 568 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 616
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G C
Sbjct: 617 VDAF---RCFCPSGWEGELC 633
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 760 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 807
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N + C CP G AG CQ + G+S
Sbjct: 808 INGYR---CSCPPGRAGPRCQEVIGFGRS 833
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 593 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 641
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC + G C N + C C G+ G +C
Sbjct: 642 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 671
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 442
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 37.5 bits (83), Expect = 0.028
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G C C C G+ G C +R C + C NGGTC
Sbjct: 645 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-----------CDAYTCSNGGTCYDSG 693
Query: 437 NSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G++C
Sbjct: 694 DTF---RCACPPGWKGSTC 709
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 516
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 3e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S ++ C CPPG+ GS C S C +PC NGGTC
Sbjct: 721 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------SCLPNPCVNGGTCV--- 767
Query: 437 NSWMNHTCDCPLGYAGASC 493
S + +C C G+ G +C
Sbjct: 768 GSGASFSCICRDGWEGRTC 786
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQM 499
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 2e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N + C CP G AG CQ + G+S
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRS 871
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C GG+C + CICP + G+ C+ N C PC
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DANECEGKPCL 433
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N +CK N + CDC G+ G +C +
Sbjct: 434 NAFSCK---NLIGGYYCDCIPGWKGINCHI 460
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 442
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 37.5 bits (83), Expect = 0.028
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G C C C G+ G C +R C + C NGGTC
Sbjct: 683 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-----------CDAYTCSNGGTCYDSG 731
Query: 437 NSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G++C
Sbjct: 732 DTF---RCACPPGWKGSTC 747
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 516
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 3e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S ++ C CPPG+ GS C S C +PC NGGTC
Sbjct: 721 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------SCLPNPCVNGGTCV--- 767
Query: 437 NSWMNHTCDCPLGYAGASC 493
S + +C C G+ G +C
Sbjct: 768 GSGASFSCICRDGWEGRTC 786
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQM 499
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 2e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N + C CP G AG CQ + G+S
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRS 871
Score = 45.2 bits (102), Expect = 1e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C GG+C + CICP + G+ C+ VN C PC
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DVNDCEGKPCL 433
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N +CK N + CDC G+ G +C +
Sbjct: 434 NAFSCK---NLIGGYYCDCIPGWKGINCHI 460
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 442
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 37.5 bits (83), Expect = 0.028
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G C C C G+ G C +R C + C NGGTC
Sbjct: 683 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-----------CDAYTCSNGGTCYDSG 731
Query: 437 NSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G++C
Sbjct: 732 DTF---RCACPPGWKGSTC 747
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 516
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLEL 511
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 9e-07
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLE 508
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 3e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 437 NSWMNHTCDCPLGYAGASCQMPLELGQS 520
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 50.4 bits (115), Expect = 4e-06
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C S ++ C CPPG+ GS C S C +PC NGGTC
Sbjct: 721 CSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------SCLPNPCVNGGTCV--- 767
Query: 437 NSWMNHTCDCPLGYAGASC 493
S + +C C G+ G +C
Sbjct: 768 GSGASFSCICRDGWEGRTC 786
Score = 49.6 bits (113), Expect = 7e-06
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +2
Query: 254 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.0 bits (109), Expect = 2e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQM 499
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 2e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 434 RNSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 48.0 bits (109), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 434 RNSWMNHTCDCPLGYAGASCQMPLELGQS 520
N + C CP G AG CQ + G+S
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRS 871
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C GG+C + CICP + G+ C+ N C PC
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DANECEGKPCL 433
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
N +CK N + CDC G+ G +C +
Sbjct: 434 NAFSCK---NLIGGYYCDCIPGWKGINCHI 460
Score = 43.6 bits (98), Expect = 4e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 442
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 37.5 bits (83), Expect = 0.028
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G C C C G+ G C +R C + C NGGTC
Sbjct: 683 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-----------CDAYTCSNGGTCYDSG 731
Query: 437 NSWMNHTCDCPLGYAGASC 493
+++ C CP G+ G++C
Sbjct: 732 DTF---RCACPPGWKGSTC 747
>U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein
precursor protein.
Length = 1642
Score = 52.4 bits (120), Expect = 9e-07
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 1344 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 1392
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N++ C C Y GA C+ E
Sbjct: 1393 NTF---RCLCLPSYVGALCEQDTE 1413
Score = 43.6 bits (98), Expect = 4e-04
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 1339 CKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 1375
>D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3)
protein.
Length = 655
Score = 52.4 bits (120), Expect = 9e-07
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 357 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 405
Query: 437 NSWMNHTCDCPLGYAGASCQMPLE 508
N++ C C Y GA C+ E
Sbjct: 406 NTF---RCLCLPSYVGALCEQDTE 426
Score = 44.4 bits (100), Expect = 2e-04
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 338 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
++R +Y P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 338 DSRFDAYCFKRP---DRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 388
>AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.
Length = 4186
Score = 52.0 bits (119), Expect = 1e-06
Identities = 25/72 (34%), Positives = 35/72 (48%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG +CET + + C +PCRNGG C +TC C +
Sbjct: 1491 CRCPPGFTGDFCETEL-----------DLCYSNPCRNGGACARREG---GYTCVCRPRFT 1536
Query: 482 GASCQMPLELGQ 517
G C++ E G+
Sbjct: 1537 GEDCELDTEAGR 1548
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ C+C P +TG CE + C CRNGGTC
Sbjct: 1514 CRNGGACARREGGYTCVCRPRFTGEDCELDTEA---------GRCVPGVCRNGGTCTDAP 1564
Query: 437 NSWMNHTCDCPLG--YAGASCQM 499
N C CP G + G C++
Sbjct: 1565 NG--GFRCQCPAGGAFEGPRCEV 1585
Score = 46.0 bits (104), Expect = 8e-05
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 4/127 (3%)
Frame = +2
Query: 128 GFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDI--QASESCQCENGGSCST--ES 295
G GCI+ V L S + + S+ N + G + A S C C ++
Sbjct: 1981 GLVGCIQGVWLGSTPSGSPALLPPSH--RVNA-EPGCVVTNACASGPCPPHADCRDLWQT 2037
Query: 296 TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLG 475
+C C PGY G C V+ C L+PC+N G+C+ + +TCDC G
Sbjct: 2038 FSCTCQPGYYGPGC--------------VDACLLNPCQNQGSCRHLPGAPHGYTCDCVGG 2083
Query: 476 YAGASCQ 496
Y G C+
Sbjct: 2084 YFGHHCE 2090
Score = 43.6 bits (98), Expect = 4e-04
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C PC+N G C W + +CDCP+G+ G CQ+ +
Sbjct: 1796 CDSGPCKNSGFCS---ERWGSFSCDCPVGFGGKDCQLTM 1831
Score = 29.9 bits (64), Expect = 5.7
Identities = 16/47 (34%), Positives = 21/47 (44%), Gaps = 5/47 (10%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSC-----STESTNCICPPGYTGSYCETRI 349
Y G + A C+N GSC + C C GY G +CE R+
Sbjct: 2047 YGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRM 2093
>AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo 1
protein.
Length = 3312
Score = 52.0 bits (119), Expect = 1e-06
Identities = 25/72 (34%), Positives = 35/72 (48%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG +CET + + C +PCRNGG C +TC C +
Sbjct: 1421 CRCPPGFTGDFCETEL-----------DLCYSNPCRNGGACARREG---GYTCVCRPRFT 1466
Query: 482 GASCQMPLELGQ 517
G C++ E G+
Sbjct: 1467 GEDCELDTEAGR 1478
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Frame = +2
Query: 263 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NGG+C+ C+C P +TG CE + C CRNGGTC
Sbjct: 1444 CRNGGACARREGGYTCVCRPRFTGEDCELDTEA---------GRCVPGVCRNGGTCTDAP 1494
Query: 437 NSWMNHTCDCPLG--YAGASCQM 499
N C CP G + G C++
Sbjct: 1495 NG--GFRCQCPAGGAFEGPRCEV 1515
Score = 46.0 bits (104), Expect = 8e-05
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 4/127 (3%)
Frame = +2
Query: 128 GFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDI--QASESCQCENGGSCST--ES 295
G GCI+ V L S + + S+ N + G + A S C C ++
Sbjct: 1911 GLVGCIQGVWLGSTPSGSPALLPPSH--RVNA-EPGCVVTNACASGPCPPHADCRDLWQT 1967
Query: 296 TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLG 475
+C C PGY G C V+ C L+PC+N G+C+ + +TCDC G
Sbjct: 1968 FSCTCQPGYYGPGC--------------VDACLLNPCQNQGSCRHLPGAPHGYTCDCVGG 2013
Query: 476 YAGASCQ 496
Y G C+
Sbjct: 2014 YFGHHCE 2020
Score = 43.6 bits (98), Expect = 4e-04
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C PC+N G C W + +CDCP+G+ G CQ+ +
Sbjct: 1726 CDSGPCKNSGFCS---ERWGSFSCDCPVGFGGKDCQLTM 1761
Score = 29.9 bits (64), Expect = 5.7
Identities = 16/47 (34%), Positives = 21/47 (44%), Gaps = 5/47 (10%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSC-----STESTNCICPPGYTGSYCETRI 349
Y G + A C+N GSC + C C GY G +CE R+
Sbjct: 1977 YGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRM 2023
>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
receptor related protein-deleted in tumor protein.
Length = 4599
Score = 52.0 bits (119), Expect = 1e-06
Identities = 34/91 (37%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Frame = +2
Query: 236 DIQASESCQ--CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
D +SC+ CENGG C C C P Y+G CE VN CS +
Sbjct: 4210 DSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCE-------------VNHCSNY 4256
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C+NGGTC P TC C LG+ G +C
Sbjct: 4257 -CQNGGTCVPSVLG--RPTCSCALGFTGPNC 4284
Score = 33.5 bits (73), Expect = 0.46
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Frame = +2
Query: 194 KSSNIQECNTYDRGDIQASESCQCENGGS---C--STEST-NCICPPGY 322
K+S + YD+ Q S SCQ NGG C ++E+T C+C GY
Sbjct: 1817 KTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGY 1865
Score = 29.9 bits (64), Expect = 5.7
Identities = 12/33 (36%), Positives = 18/33 (54%)
Frame = +2
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C NGGTC+ D + + C C ++G C+ P
Sbjct: 4398 CYNGGTCQLDPETNV-PVCLCSTNWSGTQCERP 4429
Score = 29.5 bits (63), Expect = 7.5
Identities = 40/151 (26%), Positives = 59/151 (39%), Gaps = 9/151 (5%)
Frame = +2
Query: 74 GGVDDSTVVVNPNAGVSGGFSG--CIKDVVLNSNAVDINSSIKSSNIQECNTYDR--GDI 241
GG +V+ P + GF+G C K V + + + N C+ GD
Sbjct: 4260 GGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDR 4319
Query: 242 QASESCQ--CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
C C N SC+ S C+CP Y G CE V+ C C
Sbjct: 4320 CQYYVCHHYCVNSESCTIGDDGSXECVCPTRYEGPKCE-------------VDKCV--RC 4364
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+GG C +++S + C+C G +SCQ+
Sbjct: 4365 -HGGHCIINKDS-EDIFCNCTNGKIASSCQL 4393
Score = 29.5 bits (63), Expect = 7.5
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQ--CENGGSCSTE-STN---CICPPGYTGSYCE 340
CN + + + C C NGG+C + TN C+C ++G+ CE
Sbjct: 4380 CNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCE 4427
>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
lipoprotein-related protein 1B variant protein.
Length = 1720
Score = 52.0 bits (119), Expect = 1e-06
Identities = 34/91 (37%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Frame = +2
Query: 236 DIQASESCQ--CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
D +SC+ CENGG C C C P Y+G CE VN CS +
Sbjct: 1331 DSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCE-------------VNHCSNY 1377
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C+NGGTC P TC C LG+ G +C
Sbjct: 1378 -CQNGGTCLPSVLG--RPTCSCALGFTGPNC 1405
Score = 29.9 bits (64), Expect = 5.7
Identities = 12/33 (36%), Positives = 18/33 (54%)
Frame = +2
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 502
C NGGTC+ D + + C C ++G C+ P
Sbjct: 1519 CYNGGTCQLDPETNV-PVCLCSTNWSGTQCERP 1550
Score = 29.5 bits (63), Expect = 7.5
Identities = 40/151 (26%), Positives = 59/151 (39%), Gaps = 9/151 (5%)
Frame = +2
Query: 74 GGVDDSTVVVNPNAGVSGGFSG--CIKDVVLNSNAVDINSSIKSSNIQECNTYDR--GDI 241
GG +V+ P + GF+G C K V + + + N C+ GD
Sbjct: 1381 GGTCLPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDR 1440
Query: 242 QASESCQ--CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
C C N SC+ S C+CP Y G CE V+ C C
Sbjct: 1441 CQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCE-------------VDKCV--RC 1485
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
+GG C +++S + C+C G +SCQ+
Sbjct: 1486 -HGGHCIINKDS-EDIFCNCTNGKIASSCQL 1514
Score = 29.5 bits (63), Expect = 7.5
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQ--CENGGSCSTE-STN---CICPPGYTGSYCE 340
CN + + + C C NGG+C + TN C+C ++G+ CE
Sbjct: 1501 CNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCE 1548
>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related precursor
(AA -19 to 4525) protein.
Length = 4544
Score = 51.6 bits (118), Expect = 2e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 260 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 4203 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 4248
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
+ TC CP G+ G C
Sbjct: 4249 SPSGMP--TCRCPTGFTGPKC 4267
Score = 38.7 bits (86), Expect = 0.012
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Frame = +2
Query: 194 KSSNIQECNTYDRGDIQASESC--QCENGGSCSTEST---NCICPPGYTGSYCETRIAS 355
K S CN D + +C C NGGSC+ S C CPP TG CE + S
Sbjct: 4356 KQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 4414
Score = 37.9 bits (84), Expect = 0.021
Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Frame = +2
Query: 215 CNTYDRGDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPP 379
C GD + C C NGG+C+ + C CP G+TG C ++
Sbjct: 4222 CQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV---------- 4271
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+ + C N TC ++ + C C G+ G CQ
Sbjct: 4272 ---CAGY-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 4304
Score = 32.3 bits (70), Expect = 1.1
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 4276 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 4321
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
+ + C C + G+ C++
Sbjct: 4322 ADG--SRQCRCTAYFEGSRCEV 4341
>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
lipoprotein-related protein 1 (alpha-2-macroglobulin
receptor) protein.
Length = 4544
Score = 51.6 bits (118), Expect = 2e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 260 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 4203 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 4248
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
+ TC CP G+ G C
Sbjct: 4249 SPSGMP--TCRCPTGFTGPKC 4267
Score = 38.7 bits (86), Expect = 0.012
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Frame = +2
Query: 194 KSSNIQECNTYDRGDIQASESC--QCENGGSCSTEST---NCICPPGYTGSYCETRIAS 355
K S CN D + +C C NGGSC+ S C CPP TG CE + S
Sbjct: 4356 KQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 4414
Score = 37.9 bits (84), Expect = 0.021
Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Frame = +2
Query: 215 CNTYDRGDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPP 379
C GD + C C NGG+C+ + C CP G+TG C ++
Sbjct: 4222 CQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV---------- 4271
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+ + C N TC ++ + C C G+ G CQ
Sbjct: 4272 ---CAGY-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 4304
Score = 32.3 bits (70), Expect = 1.1
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 4276 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 4321
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
+ + C C + G+ C++
Sbjct: 4322 ADG--SRQCRCTAYFEGSRCEV 4341
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Frame = +2
Query: 158 LNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGS 331
LNS VD+ K +Q+ T D+ + S C+NGG+C +S CICPP + G
Sbjct: 113 LNSKLVDLER--KFQGLQQ--TVDK---KVCSSNPCQNGGTCLNLHDSFFCICPPQWKGP 165
Query: 332 YCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + + P++ C+NGGTC N+ +++C CP G C
Sbjct: 166 LCSADVNECEIYSGTPLS------CQNGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = +2
Query: 233 GDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +Q S C C NG T S C C G+TG C I N C +
Sbjct: 391 GCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI-----------NECLSN 439
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQS 520
PC NGGTC +S+ +C+C + GA CQ+P ++ G+S
Sbjct: 440 PCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGES 477
Score = 37.9 bits (84), Expect = 0.021
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 11/110 (10%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQA---SESCQCENGG-----SCSTESTN---CICPPGYTGSYCET 343
SS+ Q C +GD + ++ C NGG SCS+ + C C PGYTG+
Sbjct: 330 SSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGP 389
Query: 344 RIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
L N C HPC N G C ++ + C C G+ G +C
Sbjct: 390 NGCVQLS------NICLSHPCLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 346
S+++ EC Y + C+NGG+C + S +C CPP G C ++
Sbjct: 168 SADVNECEIY------SGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Frame = +2
Query: 158 LNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGS 331
LNS VD+ K +Q+ T D+ + S C+NGG+C +S CICPP + G
Sbjct: 113 LNSKLVDLER--KFQGLQQ--TVDK---KVCSSNPCQNGGTCLNLHDSFFCICPPQWKGP 165
Query: 332 YCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + + P++ C+NGGTC N+ +++C CP G C
Sbjct: 166 LCSADVNECEIYSGTPLS------CQNGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = +2
Query: 233 GDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +Q S C C NG T S C C G+TG C I N C +
Sbjct: 391 GCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI-----------NECLSN 439
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQS 520
PC NGGTC +S+ +C+C + GA CQ+P ++ G+S
Sbjct: 440 PCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGES 477
Score = 37.9 bits (84), Expect = 0.021
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 11/110 (10%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQA---SESCQCENGG-----SCSTESTN---CICPPGYTGSYCET 343
SS+ Q C +GD + ++ C NGG SCS+ + C C PGYTG+
Sbjct: 330 SSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGP 389
Query: 344 RIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
L N C HPC N G C ++ + C C G+ G +C
Sbjct: 390 NGCVQLS------NICLSHPCLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 346
S+++ EC Y + C+NGG+C + S +C CPP G C ++
Sbjct: 168 SADVNECEIY------SGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Frame = +2
Query: 158 LNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGS 331
LNS VD+ K +Q+ T D+ + S C+NGG+C +S CICPP + G
Sbjct: 113 LNSKLVDLER--KFQGLQQ--TVDK---KVCSSNPCQNGGTCLNLHDSFFCICPPQWKGP 165
Query: 332 YCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + + P++ C+NGGTC N+ +++C CP G C
Sbjct: 166 LCSADVNECEIYSGTPLS------CQNGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = +2
Query: 233 GDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +Q S C C NG T S C C G+TG C I N C +
Sbjct: 391 GCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI-----------NECLSN 439
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQS 520
PC NGGTC +S+ +C+C + GA CQ+P ++ G+S
Sbjct: 440 PCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGES 477
Score = 37.9 bits (84), Expect = 0.021
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 11/110 (10%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQA---SESCQCENGG-----SCSTESTN---CICPPGYTGSYCET 343
SS+ Q C +GD + ++ C NGG SCS+ + C C PGYTG+
Sbjct: 330 SSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGP 389
Query: 344 RIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
L N C HPC N G C ++ + C C G+ G +C
Sbjct: 390 NGCVQLS------NICLSHPCLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 346
S+++ EC Y + C+NGG+C + S +C CPP G C ++
Sbjct: 168 SADVNECEIY------SGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 3/134 (2%)
Frame = +2
Query: 119 VSGGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQ-ASESCQCENGGSC--ST 289
V GF GC++ V + ++ +++ +N + D D+ S C C +
Sbjct: 1833 VRRGFRGCMQGVRMGGTPTNV-ATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAW 1891
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
E +C+C GY G C V+ C L+PC N G C S + C+C
Sbjct: 1892 EDYSCVCDKGYLGINC--------------VDACHLNPCENMGACVRSPGSPQGYVCECG 1937
Query: 470 LGYAGASCQMPLEL 511
+ G C+ L+L
Sbjct: 1938 PSHYGPYCENKLDL 1951
Score = 44.8 bits (101), Expect = 2e-04
Identities = 24/72 (33%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET I + C PC G C R+ +TC+C +
Sbjct: 1349 CRCPPGFTGDYCETEI-----------DLCYSDPCGANGRC---RSREGGYTCECFEDFT 1394
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1395 GEHCEVDARSGR 1406
Score = 41.5 bits (93), Expect = 0.002
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C C+NGGTC N W + C+CPL + G +C+ +
Sbjct: 1651 NFCDGRRCQNGGTCV---NRWNMYLCECPLRFGGKNCEQAM 1688
Score = 34.7 bits (76), Expect = 0.20
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPG-YTGSYCETRIASY 358
C+NGG+C +C+CPPG Y YCE S+
Sbjct: 1412 CKNGGTCVNLLIGGFHCVCPPGEYERPYCEVTTRSF 1447
Score = 32.7 bits (71), Expect = 0.80
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +2
Query: 131 FSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--C 304
F GC++++ ++ VD+ I ++ +E R + +C+NGG+C C
Sbjct: 1617 FVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRN---FCDGRRCQNGGTCVNRWNMYLC 1673
Query: 305 ICPPGYTGSYCE 340
CP + G CE
Sbjct: 1674 ECPLRFGGKNCE 1685
Score = 29.9 bits (64), Expect = 5.7
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y +I S C G C + C C +TG +CE S C+
Sbjct: 1359 YCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARS---------GRCAN 1409
Query: 398 HPCRNGGTC 424
C+NGGTC
Sbjct: 1410 GVCKNGGTC 1418
>AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 3/134 (2%)
Frame = +2
Query: 119 VSGGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQ-ASESCQCENGGSC--ST 289
V GF GC++ V + ++ +++ +N + D D+ S C C +
Sbjct: 1833 VRRGFRGCMQGVRMGGTPTNV-ATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAW 1891
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
E +C+C GY G C V+ C L+PC N G C S + C+C
Sbjct: 1892 EDYSCVCDKGYLGINC--------------VDACHLNPCENMGACVRSPGSPQGYVCECG 1937
Query: 470 LGYAGASCQMPLEL 511
+ G C+ L+L
Sbjct: 1938 PSHYGPYCENKLDL 1951
Score = 44.8 bits (101), Expect = 2e-04
Identities = 24/72 (33%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET I + C PC G C R+ +TC+C +
Sbjct: 1349 CRCPPGFTGDYCETEI-----------DLCYSDPCGANGRC---RSREGGYTCECFEDFT 1394
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1395 GEHCEVDARSGR 1406
Score = 41.5 bits (93), Expect = 0.002
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C C+NGGTC N W + C+CPL + G +C+ +
Sbjct: 1651 NFCDGRRCQNGGTCV---NRWNMYLCECPLRFGGKNCEQAM 1688
Score = 34.7 bits (76), Expect = 0.20
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPG-YTGSYCETRIASY 358
C+NGG+C +C+CPPG Y YCE S+
Sbjct: 1412 CKNGGTCVNLLIGGFHCVCPPGEYERPYCEVTTRSF 1447
Score = 32.7 bits (71), Expect = 0.80
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +2
Query: 131 FSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--C 304
F GC++++ ++ VD+ I ++ +E R + +C+NGG+C C
Sbjct: 1617 FVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRN---FCDGRRCQNGGTCVNRWNMYLC 1673
Query: 305 ICPPGYTGSYCE 340
CP + G CE
Sbjct: 1674 ECPLRFGGKNCE 1685
Score = 29.9 bits (64), Expect = 5.7
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y +I S C G C + C C +TG +CE S C+
Sbjct: 1359 YCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARS---------GRCAN 1409
Query: 398 HPCRNGGTC 424
C+NGGTC
Sbjct: 1410 GVCKNGGTC 1418
>AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 1 (flamingo homolog, Drosophila) protein.
Length = 3014
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 3/134 (2%)
Frame = +2
Query: 119 VSGGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQ-ASESCQCENGGSC--ST 289
V GF GC++ V + ++ +++ +N + D D+ S C C +
Sbjct: 1833 VRRGFRGCMQGVRMGGTPTNV-ATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAW 1891
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
E +C+C GY G C V+ C L+PC N G C S + C+C
Sbjct: 1892 EDYSCVCDKGYLGINC--------------VDACHLNPCENMGACVRSPGSPQGYVCECG 1937
Query: 470 LGYAGASCQMPLEL 511
+ G C+ L+L
Sbjct: 1938 PSHYGPYCENKLDL 1951
Score = 44.8 bits (101), Expect = 2e-04
Identities = 24/72 (33%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET I + C PC G C R+ +TC+C +
Sbjct: 1349 CRCPPGFTGDYCETEI-----------DLCYSDPCGANGRC---RSREGGYTCECFEDFT 1394
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1395 GEHCEVDARSGR 1406
Score = 41.5 bits (93), Expect = 0.002
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C C+NGGTC N W + C+CPL + G +C+ +
Sbjct: 1651 NFCDGRRCQNGGTCV---NRWNMYLCECPLRFGGKNCEQAM 1688
Score = 34.7 bits (76), Expect = 0.20
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPG-YTGSYCETRIASY 358
C+NGG+C +C+CPPG Y YCE S+
Sbjct: 1412 CKNGGTCVNLLIGGFHCVCPPGEYERPYCEVTTRSF 1447
Score = 32.7 bits (71), Expect = 0.80
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +2
Query: 131 FSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--C 304
F GC++++ ++ VD+ I ++ +E R + +C+NGG+C C
Sbjct: 1617 FVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRN---FCDGRRCQNGGTCVNRWNMYLC 1673
Query: 305 ICPPGYTGSYCE 340
CP + G CE
Sbjct: 1674 ECPLRFGGKNCE 1685
Score = 29.9 bits (64), Expect = 5.7
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y +I S C G C + C C +TG +CE S C+
Sbjct: 1359 YCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARS---------GRCAN 1409
Query: 398 HPCRNGGTC 424
C+NGGTC
Sbjct: 1410 GVCKNGGTC 1418
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 51.6 bits (118), Expect = 2e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Frame = +2
Query: 263 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPNGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 428 PDRNSWMNHTCDCPLGYAGASCQMPLE 508
RN + C CPLGYAG +C+ ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCETEVD 148
Score = 50.8 bits (116), Expect = 3e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI S C +G +C + C CP GY G CET V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCETE-----------VDECASAPCL 156
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 520
+G +C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGASCLDGVGSF---RCVCAPGYGGTRCQLDLDECQS 190
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 3/90 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C +G SC S C+C PGY G+ C+ + + C PC
Sbjct: 146 EVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDL-----------DECQSQPCA 194
Query: 410 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 496
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 482 GASCQ 496
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 3e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 41.9 bits (94), Expect = 0.001
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 221 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 395 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPLE 508
P GG P S+ + C CP G+ GA C + ++
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD 322
Score = 39.9 bits (89), Expect = 0.005
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +2
Query: 302 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 478
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPNGFRCYCVPGF 100
Query: 479 AGASCQMPLE 508
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 38.7 bits (86), Expect = 0.012
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 35.9 bits (79), Expect = 0.086
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCAR-GRCHTHP 1112
Query: 437 NSWMNHTCDCPLGYAGASCQ 496
+ C CP G+ G C+
Sbjct: 1113 DG--RFECRCPPGFGGPRCR 1130
Score = 31.1 bits (67), Expect = 2.4
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Frame = +2
Query: 125 GGFSGCIKDVVLNSN-----AVDINSSIKSSNIQECNTYD-RGDIQASESCQ---CENGG 277
G F GC++D+ L+ + +++S + S + +++ + + C C NGG
Sbjct: 761 GPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGG 820
Query: 278 SC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 424
+C + +C CP +TG C A L P P + P + +G C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo 2
protein.
Length = 3014
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 3/134 (2%)
Frame = +2
Query: 119 VSGGFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQ-ASESCQCENGGSC--ST 289
V GF GC++ V + ++ +++ +N + D D+ S C C +
Sbjct: 1833 VRRGFRGCMQGVRMGGTPTNV-ATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAW 1891
Query: 290 ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
E +C+C GY G C V+ C L+PC N G C S + C+C
Sbjct: 1892 EDYSCVCDKGYLGINC--------------VDACHLNPCENMGACVRSPGSPQGYVCECG 1937
Query: 470 LGYAGASCQMPLEL 511
+ G C+ L+L
Sbjct: 1938 PSHYGPYCENKLDL 1951
Score = 44.8 bits (101), Expect = 2e-04
Identities = 24/72 (33%), Positives = 33/72 (45%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CPPG+TG YCET I + C PC G C R+ +TC+C +
Sbjct: 1349 CRCPPGFTGDYCETEI-----------DLCYSDPCGANGRC---RSREGGYTCECFEDFT 1394
Query: 482 GASCQMPLELGQ 517
G C++ G+
Sbjct: 1395 GEHCEVDARSGR 1406
Score = 41.5 bits (93), Expect = 0.002
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
N C C+NGGTC N W + C+CPL + G +C+ +
Sbjct: 1651 NFCDGRRCQNGGTCV---NRWNMYLCECPLRFGGKNCEQAM 1688
Score = 34.7 bits (76), Expect = 0.20
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPG-YTGSYCETRIASY 358
C+NGG+C +C+CPPG Y YCE S+
Sbjct: 1412 CKNGGTCVNLLIGGFHCVCPPGEYERPYCEVTTRSF 1447
Score = 32.7 bits (71), Expect = 0.80
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +2
Query: 131 FSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN--C 304
F GC++++ ++ VD+ I ++ +E R + +C+NGG+C C
Sbjct: 1617 FVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRN---FCDGRRCQNGGTCVNRWNMYLC 1673
Query: 305 ICPPGYTGSYCE 340
CP + G CE
Sbjct: 1674 ECPLRFGGKNCE 1685
Score = 29.9 bits (64), Expect = 5.7
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Frame = +2
Query: 224 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 397
Y +I S C G C + C C +TG +CE S C+
Sbjct: 1359 YCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARS---------GRCAN 1409
Query: 398 HPCRNGGTC 424
C+NGGTC
Sbjct: 1410 GVCKNGGTC 1418
>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-related
protein protein.
Length = 4544
Score = 51.6 bits (118), Expect = 2e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 260 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 4203 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 4248
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
+ TC CP G+ G C
Sbjct: 4249 SPSGMP--TCRCPTGFTGPKC 4267
Score = 38.7 bits (86), Expect = 0.012
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Frame = +2
Query: 194 KSSNIQECNTYDRGDIQASESC--QCENGGSCSTEST---NCICPPGYTGSYCETRIAS 355
K S CN D + +C C NGGSC+ S C CPP TG CE + S
Sbjct: 4356 KQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 4414
Score = 37.9 bits (84), Expect = 0.021
Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Frame = +2
Query: 215 CNTYDRGDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPP 379
C GD + C C NGG+C+ + C CP G+TG C ++
Sbjct: 4222 CQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV---------- 4271
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+ + C N TC ++ + C C G+ G CQ
Sbjct: 4272 ---CAGY-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 4304
Score = 32.3 bits (70), Expect = 1.1
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 4276 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 4321
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
+ + C C + G+ C++
Sbjct: 4322 ADG--SRQCRCTAYFEGSRCEV 4341
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Frame = +2
Query: 158 LNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGS 331
LNS VD+ K +Q+ T D+ + S C+NGG+C +S CICPP + G
Sbjct: 113 LNSKLVDLER--KFQGLQQ--TVDK---KVCSSNPCQNGGNCLNLHDSFFCICPPQWKGP 165
Query: 332 YCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C + + P++ C+NGGTC N+ +++C CP G C
Sbjct: 166 LCSADVNECEIYSGTPLS------CQNGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = +2
Query: 233 GDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +Q S C C NG T S C C G+TG C I N C +
Sbjct: 391 GCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI-----------NECLSN 439
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQS 520
PC NGGTC +S+ +C+C + GA CQ+P ++ G+S
Sbjct: 440 PCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGES 477
Score = 37.9 bits (84), Expect = 0.021
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 11/110 (10%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQA---SESCQCENGG-----SCSTESTN---CICPPGYTGSYCET 343
SS+ Q C +GD + ++ C NGG SCS+ + C C PGYTG+
Sbjct: 330 SSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGP 389
Query: 344 RIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
L N C HPC N G C ++ + C C G+ G +C
Sbjct: 390 NGCVQLS------NICLSHPCLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 346
S+++ EC Y + C+NGG+C + S +C CPP G C ++
Sbjct: 168 SADVNECEIY------SGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AB209498-1|BAD92735.1| 2359|Homo sapiens low density
lipoprotein-related protein 1 variant protein.
Length = 2359
Score = 51.6 bits (118), Expect = 2e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 260 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 2018 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 2063
Query: 431 DRNSWMNHTCDCPLGYAGASC 493
+ TC CP G+ G C
Sbjct: 2064 SPSGMP--TCRCPTGFTGPKC 2082
Score = 38.7 bits (86), Expect = 0.012
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Frame = +2
Query: 194 KSSNIQECNTYDRGDIQASESC--QCENGGSCSTEST---NCICPPGYTGSYCETRIAS 355
K S CN D + +C C NGGSC+ S C CPP TG CE + S
Sbjct: 2171 KQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 2229
Score = 37.9 bits (84), Expect = 0.021
Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Frame = +2
Query: 215 CNTYDRGDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPP 379
C GD + C C NGG+C+ + C CP G+TG C ++
Sbjct: 2037 CQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV---------- 2086
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C+ + C N TC ++ + C C G+ G CQ
Sbjct: 2087 ---CAGY-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 2119
Score = 32.3 bits (70), Expect = 1.1
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 2091 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 2136
Query: 434 RNSWMNHTCDCPLGYAGASCQM 499
+ + C C + G+ C++
Sbjct: 2137 ADG--SRQCRCTAYFEGSRCEV 2156
>AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein.
Length = 522
Score = 50.8 bits (116), Expect = 3e-06
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Frame = +2
Query: 245 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
A +S C++GG C + C+CP + G +CET +PC PC G
Sbjct: 2 ACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCET-----------VSDPCFSSPCGGRG 50
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C S H+C C +GY G C L
Sbjct: 51 YCLASNGS---HSCTCKVGYTGEDCAKEL 76
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 499
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 448 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 481
Score = 34.3 bits (75), Expect = 0.26
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 453 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 508
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 50.4 bits (115), Expect = 4e-06
Identities = 23/66 (34%), Positives = 34/66 (51%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C P + C + +Y PP C+ HPC+NGG+C+P +S TC CP +
Sbjct: 2645 CASNPCWGDLLCINQWYAYRCVPP---GDCASHPCQNGGSCEPGLHS--GFTCSCPDSHT 2699
Query: 482 GASCQM 499
G +C+M
Sbjct: 2700 GRTCEM 2705
Score = 46.0 bits (104), Expect = 8e-05
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C C PGY GS+CE ++ C PC +GGTC N +C CP G+
Sbjct: 2146 CKCLPGYAGSWCEI-----------DIDECLPSPCHSGGTC---HNLVGGFSCSCPDGFT 2191
Query: 482 GASCQ 496
G +C+
Sbjct: 2192 GRACE 2196
Score = 45.6 bits (103), Expect = 1e-04
Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 2/85 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
DI C +GG+C +C CP G+TG CE +N C PC+
Sbjct: 2160 DIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACER-----------DINECLQSPCK 2208
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAG 484
NG C+ S+ C C GY G
Sbjct: 2209 NGAICQNFPGSF---NCVCKTGYTG 2230
Score = 33.5 bits (73), Expect = 0.46
Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 3/33 (9%)
Frame = +2
Query: 263 CENGGSCST---ESTNCICPPGYTGSYCETRIA 352
C+NGGSC C CP +TG CE +A
Sbjct: 2676 CQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVA 2708
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSY 334
DI C+NG C S NC+C GYTG +
Sbjct: 2198 DINECLQSPCKNGAICQNFPGSFNCVCKTGYTGVF 2232
>BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein
protein.
Length = 236
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 1e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 482 GASCQ 496
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 200 TGDFTFECNC 209
>BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein.
Length = 249
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 43 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 93
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 94 TC--HMLSRDTYECTCQVGFTGKECQ 117
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 9 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 55
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 56 QAMLGKATCRCASGFTGEDCQ 76
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 89 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 136
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 137 ANQF---SCKCLTGFTGQKCE 154
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 166 CQHGGICLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 212
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 213 TGDFTFECNC 222
Score = 40.7 bits (91), Expect = 0.003
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GG C
Sbjct: 127 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGIC--- 172
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 173 LNLPGSYQCQCLQGFTGQYC 192
>BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein.
Length = 343
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 137 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 187
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 188 TC--HMLSRDTYECTCQVGFTGKECQ 211
Score = 49.2 bits (112), Expect = 9e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 103 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 149
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 150 QAMLGKATCRCASGFTGEDCQ 170
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 183 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 230
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 231 ANQF---SCKCLTGFTGQKCE 248
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 221 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 266
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 267 LNLPGSYQCQCLQGFTGQYC 286
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 260 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 306
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 307 TGDFTFECNC 316
>BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 1e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 482 GASCQ 496
G CQ
Sbjct: 59 GEDCQ 63
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGICLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 200 TGDFTFECNC 209
Score = 40.7 bits (91), Expect = 0.003
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GG C
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGIC--- 159
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
>BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-terminal
like protein protein.
Length = 236
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 1e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 482 GASCQ 496
G CQ
Sbjct: 59 GEDCQ 63
Score = 41.5 bits (93), Expect = 0.002
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGICLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 200 TGDFTFECNC 209
Score = 40.7 bits (91), Expect = 0.003
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GG C
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGIC--- 159
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
>BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 1e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 482 GASCQ 496
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 200 TGDFTFECNC 209
>AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 230
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 1e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 482 GASCQ 496
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 200 TGDFTFECNC 209
>AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 1e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 482 GASCQ 496
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 200 TGDFTFECNC 209
>AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens
cDNA FLJ90584 fis, clone PLACE1000740, highly similar to
Neurogenic locus notch homolog protein 2 precursor. ).
Length = 269
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C N G C T C CP G++G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFSGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 50.0 bits (114), Expect = 5e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +2
Query: 251 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASCQ 496
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +2
Query: 263 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 433
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 434 RNSWMNHTCDCPLGYAGASCQ 496
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 43.2 bits (97), Expect = 6e-04
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 263 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 433
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 434 RNSWMNHTCDCPLGYAGASC 493
N ++ C C G+ G C
Sbjct: 199 LNLPGSYQCQCLQGFTGQYC 218
Score = 42.7 bits (96), Expect = 8e-04
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 263 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 437 NSWMNHTCDC 466
C+C
Sbjct: 239 TGDFTFECNC 248
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 50.0 bits (114), Expect = 5e-06
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 236 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 409
D + S C+NGG+C +S CICPP + G C + + P++ C+
Sbjct: 3 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS------CQ 56
Query: 410 NGGTCKPDRNSWMNHTCDCPLGYAGASC 493
NGGTC N+ +++C CP G C
Sbjct: 57 NGGTCV---NTMGSYSCHCPPETYGPQC 81
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = +2
Query: 233 GDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 400
G +Q S C C NG T S C C G+TG C I N C +
Sbjct: 262 GCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI-----------NECLSN 310
Query: 401 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQS 520
PC NGGTC +S+ +C+C + GA CQ+P ++ G+S
Sbjct: 311 PCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGES 348
Score = 37.9 bits (84), Expect = 0.021
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 11/110 (10%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQA---SESCQCENGG-----SCSTESTN---CICPPGYTGSYCET 343
SS+ Q C +GD + ++ C NGG SCS+ + C C PGYTG+
Sbjct: 201 SSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGP 260
Query: 344 RIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
L N C HPC N G C ++ + C C G+ G +C
Sbjct: 261 NGCVQLS------NICLSHPCLN-GQC---IDTVSGYFCKCDSGWTGVNC 300
Score = 32.7 bits (71), Expect = 0.80
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Frame = +2
Query: 197 SSNIQECNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 346
S+++ EC Y + C+NGG+C + S +C CPP G C ++
Sbjct: 39 SADVNECEIY------SGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 84
>X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase
protein.
Length = 1138
Score = 49.6 bits (113), Expect = 7e-06
Identities = 24/78 (30%), Positives = 32/78 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C +GG C C+CPPG+TG+ CE + CR C PD
Sbjct: 231 CLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPD--- 287
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C C G+ G+ CQ
Sbjct: 288 --PYGCSCGSGWRGSQCQ 303
Score = 44.0 bits (99), Expect = 3e-04
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Frame = +2
Query: 116 GVSG--GFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST 289
G+SG G + C+ D S + S QE CQC+NGG+C
Sbjct: 274 GISGCRGLTFCLPDPY----GCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDR 329
Query: 290 ESTNCICPPGYTGSYCE 340
S C+CP G+ G +CE
Sbjct: 330 FS-GCVCPSGWHGVHCE 345
Score = 38.3 bits (85), Expect = 0.016
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRN 439
C C + C C G+ GS C+ A P C L C+NGGTC DR
Sbjct: 278 CRGLTFCLPDPYGCSCGSGWRGSQCQEACA-----PGHFGADCRLQCQCQNGGTC--DRF 330
Query: 440 SWMNHTCDCPLGYAGASCQ 496
S C CP G+ G C+
Sbjct: 331 S----GCVCPSGWHGVHCE 345
>BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 49.6 bits (113), Expect = 7e-06
Identities = 24/78 (30%), Positives = 32/78 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C +GG C C+CPPG+TG+ CE + CR C PD
Sbjct: 231 CLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPD--- 287
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C C G+ G+ CQ
Sbjct: 288 --PYGCSCGSGWRGSQCQ 303
Score = 44.0 bits (99), Expect = 3e-04
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Frame = +2
Query: 116 GVSG--GFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST 289
G+SG G + C+ D S + S QE CQC+NGG+C
Sbjct: 274 GISGCRGLTFCLPDPY----GCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDR 329
Query: 290 ESTNCICPPGYTGSYCE 340
S C+CP G+ G +CE
Sbjct: 330 FS-GCVCPSGWHGVHCE 345
Score = 38.3 bits (85), Expect = 0.016
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRN 439
C C + C C G+ GS C+ A P C L C+NGGTC DR
Sbjct: 278 CRGLTFCLPDPYGCSCGSGWRGSQCQEACA-----PGHFGADCRLQCQCQNGGTC--DRF 330
Query: 440 SWMNHTCDCPLGYAGASCQ 496
S C CP G+ G C+
Sbjct: 331 S----GCVCPSGWHGVHCE 345
>AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 49.6 bits (113), Expect = 7e-06
Identities = 24/78 (30%), Positives = 32/78 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C +GG C C+CPPG+TG+ CE + CR C PD
Sbjct: 231 CLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPD--- 287
Query: 443 WMNHTCDCPLGYAGASCQ 496
+ C C G+ G+ CQ
Sbjct: 288 --PYGCSCGSGWRGSQCQ 303
Score = 44.0 bits (99), Expect = 3e-04
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Frame = +2
Query: 116 GVSG--GFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQCENGGSCST 289
G+SG G + C+ D S + S QE CQC+NGG+C
Sbjct: 274 GISGCRGLTFCLPDPY----GCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDR 329
Query: 290 ESTNCICPPGYTGSYCE 340
S C+CP G+ G +CE
Sbjct: 330 FS-GCVCPSGWHGVHCE 345
Score = 38.3 bits (85), Expect = 0.016
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRN 439
C C + C C G+ GS C+ A P C L C+NGGTC DR
Sbjct: 278 CRGLTFCLPDPYGCSCGSGWRGSQCQEACA-----PGHFGADCRLQCQCQNGGTC--DRF 330
Query: 440 SWMNHTCDCPLGYAGASCQ 496
S C CP G+ G C+
Sbjct: 331 S----GCVCPSGWHGVHCE 345
>M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.
Length = 1609
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 17/107 (15%)
Frame = +2
Query: 209 QECNTYDRG--DIQASESCQ-CE------NGGSCSTESTNCICPPGYTGSYCETRIASYL 361
Q+C D G ++Q+ + C+ C+ G C + C C PG TG +CE ++
Sbjct: 914 QDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Query: 362 MSPPPPVNPCSLHP-------CRNGGTCKPDRNSWMNHTCD-CPLGY 478
P PC HP C++ G C+ R ++ + CD C Y
Sbjct: 974 GFGPEGCKPCDCHPEGSLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 445
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 446 MNHTCDCPLGYAGASCQ 496
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.7 bits (86), Expect = 0.012
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +2
Query: 218 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 388
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNVETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +2
Query: 251 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 406
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.
Length = 1609
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 17/107 (15%)
Frame = +2
Query: 209 QECNTYDRG--DIQASESCQ-CE------NGGSCSTESTNCICPPGYTGSYCETRIASYL 361
Q+C D G ++Q+ + C+ C+ G C + C C PG TG +CE ++
Sbjct: 914 QDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Query: 362 MSPPPPVNPCSLHP-------CRNGGTCKPDRNSWMNHTCD-CPLGY 478
P PC HP C++ G C+ R ++ + CD C Y
Sbjct: 974 GFGPEGCKPCDCHPEGSLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 445
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 446 MNHTCDCPLGYAGASCQ 496
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.7 bits (86), Expect = 0.012
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +2
Query: 218 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 388
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNVETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +2
Query: 251 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 406
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>BC031251-1|AAH31251.1| 375|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 375
Score = 49.2 bits (112), Expect = 9e-06
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSS-NIQECNT 223
++ T +F+GGV + V N+GV FSG I+ ++LN + + S N++
Sbjct: 94 IKCNTDIFIGGVPNYDDV-KKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA-- 150
Query: 224 YDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSP 370
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 151 -----AHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 196
Score = 46.4 bits (105), Expect = 6e-05
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+PC PC +GG+C+P + + CDCPLG+ G CQ
Sbjct: 152 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQ 186
>AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 17/107 (15%)
Frame = +2
Query: 209 QECNTYDRG--DIQASESCQ-CE------NGGSCSTESTNCICPPGYTGSYCETRIASYL 361
Q+C D G ++Q+ + C+ C+ G C + C C PG TG +CE ++
Sbjct: 914 QDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Query: 362 MSPPPPVNPCSLHP-------CRNGGTCKPDRNSWMNHTCD-CPLGY 478
P PC HP C++ G C+ R ++ + CD C Y
Sbjct: 974 GFGPEGCKPCDCHPEGSLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 445
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 446 MNHTCDCPLGYAGASCQ 496
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.3 bits (85), Expect = 0.016
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +2
Query: 218 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 388
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNIETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +2
Query: 251 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 406
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 49.2 bits (112), Expect = 9e-06
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 17/107 (15%)
Frame = +2
Query: 209 QECNTYDRG--DIQASESCQ-CE------NGGSCSTESTNCICPPGYTGSYCETRIASYL 361
Q+C D G ++Q+ + C+ C+ G C + C C PG TG +CE ++
Sbjct: 914 QDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Query: 362 MSPPPPVNPCSLHP-------CRNGGTCKPDRNSWMNHTCD-CPLGY 478
P PC HP C++ G C+ R ++ + CD C Y
Sbjct: 974 GFGPEGCKPCDCHPEGSLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +2
Query: 275 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 445
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 446 MNHTCDCPLGYAGASCQ 496
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.3 bits (85), Expect = 0.016
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +2
Query: 218 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 388
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNIETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +2
Query: 251 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 406
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>AK092479-1|BAC03900.1| 463|Homo sapiens protein ( Homo sapiens
cDNA FLJ35160 fis, clone PLACE6011334, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 463
Score = 49.2 bits (112), Expect = 9e-06
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Frame = +2
Query: 47 LRFETPMFVGGVDDSTVVVNPNAGVSGGFSGCIKDVVLNSNAVDINSSIKSS-NIQECNT 223
++ T +F+GGV + V N+GV FSG I+ ++LN + + S N++
Sbjct: 182 IKCNTDIFIGGVPNYDDV-KKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA-- 238
Query: 224 YDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSP 370
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 239 -----AHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 284
Score = 46.4 bits (105), Expect = 6e-05
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+PC PC +GG+C+P + + CDCPLG+ G CQ
Sbjct: 240 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQ 274
Score = 32.7 bits (71), Expect = 0.80
Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Frame = +2
Query: 251 ESCQCENGGSCST---ESTNCICPPGYTGSYCE 340
+ C +GG+C+ +S C+CP G+ G +CE
Sbjct: 24 DEASCIHGGTCTAIKADSYICLCPLGFKGRHCE 56
Score = 31.5 bits (68), Expect = 1.9
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +2
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
C C +GGTC + ++ C CPLG+ G C+
Sbjct: 23 CDEASCIHGGTCTAIKAD--SYICLCPLGFKGRHCE 56
>AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ14712 fis, clone NT2RP3000825, weakly similar to
NEUROGENIC LOCUS NOTCH 3 PROTEIN. ).
Length = 849
Score = 49.2 bits (112), Expect = 9e-06
Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 128 GFSGCIKDVVLNSNAVDINSSIKSSNIQECNTYDRGDIQASESCQ--CENGGSCSTESTN 301
GF G + ++ + + + +I +C G ++ C C NGGSC+ +T
Sbjct: 642 GFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNT- 700
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C+CP G+ G +C+ +P PC+NGG C N+ C C GY
Sbjct: 701 CLCPNGFFGEHCQNAFC----------HP----PCKNGGHC------MRNNVCVCREGYT 740
Query: 482 GASCQ 496
G CQ
Sbjct: 741 GRRCQ 745
Score = 47.6 bits (108), Expect = 3e-05
Identities = 28/81 (34%), Positives = 34/81 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C NGG C ST C CP G++G C T P L C+NGG C
Sbjct: 753 CMNGGKCVGPST-CSCPSGWSGKRCNT--------------PICLQKCKNGGECIAPS-- 795
Query: 443 WMNHTCDCPLGYAGASCQMPL 505
C CP + G CQ+P+
Sbjct: 796 ----ICHCPSSWEGVRCQIPI 812
Score = 45.2 bits (102), Expect = 1e-04
Identities = 27/81 (33%), Positives = 34/81 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C+C GYTG C+ I P C NGG C
Sbjct: 721 CKNGGHCMRNNV-CVCREGYTGRRCQKSICD-------PT-------CMNGGKCVGPS-- 763
Query: 443 WMNHTCDCPLGYAGASCQMPL 505
TC CP G++G C P+
Sbjct: 764 ----TCSCPSGWSGKRCNTPI 780
Score = 43.2 bits (97), Expect = 6e-04
Identities = 36/111 (32%), Positives = 45/111 (40%), Gaps = 11/111 (9%)
Frame = +2
Query: 203 NIQECNTYDRGDIQASESCQ--CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP 376
NI +C G E C C++GG C + C CP G+ G CET +
Sbjct: 603 NICQCLPGHGGATCDEEHCNPPCQHGGICLAGNL-CTCPYGFVGPRCETMV--------- 652
Query: 377 PVNPCSLHPCRNGGTC-KPD----RNSWMNHTCD---C-PLGYAGASCQMP 502
C+ H C NGG C PD + W TC C P+ G SC P
Sbjct: 653 ----CNRH-CENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKP 698
Score = 42.7 bits (96), Expect = 8e-04
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 9/95 (9%)
Frame = +2
Query: 212 ECNTYDRGDIQAS-ESCQCENGGSCSTESTN--------CICPPGYTGSYCETRIASYLM 364
+C+ R I+ + +SC C NGGSC ++ C+C PG+ GS CE I+
Sbjct: 424 DCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISG--- 480
Query: 365 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
C +PC G + + +++CDCP
Sbjct: 481 --------CQSNPCGLGSYI----SGFHSYSCDCP 503
Score = 36.7 bits (81), Expect = 0.049
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 14/129 (10%)
Frame = +2
Query: 152 VVLNSNAVDINSSIKSSNIQECNTYDRGDI-QASESCQCENGGSCSTESTN-CICPPGYT 325
VVL + +N N Q + + A C+ G S + N C C PGY
Sbjct: 521 VVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYI 580
Query: 326 GSYCETRIAS-YLMSPPPPVNP--CSLHPCRNGGTCKPDR-NSWMNH--------TCDCP 469
GS C+T + + + P C P G TC + N H C CP
Sbjct: 581 GSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGICLAGNLCTCP 640
Query: 470 LGYAGASCQ 496
G+ G C+
Sbjct: 641 YGFVGPRCE 649
>D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein.
Length = 830
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 31.9 bits (69), Expect = 1.4
Identities = 25/103 (24%), Positives = 34/103 (33%), Gaps = 1/103 (0%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVN 385
Q C G+ + C +G +C ++ +C C PG+ G CE P P
Sbjct: 295 QPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTG 345
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC + C C GY G SC G
Sbjct: 346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAG 388
Score = 31.1 bits (67), Expect = 2.4
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 1/73 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C T G+ S C G SC T + +C+C GY G C + N CS
Sbjct: 342 CPTGTFGEDCGSTCPTCVQG-SCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCS 395
Query: 395 LHPCR-NGGTCKP 430
+ PC G C P
Sbjct: 396 V-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein.
Length = 830
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 31.9 bits (69), Expect = 1.4
Identities = 25/103 (24%), Positives = 34/103 (33%), Gaps = 1/103 (0%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVN 385
Q C G+ + C +G +C ++ +C C PG+ G CE P P
Sbjct: 295 QPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTG 345
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC + C C GY G SC G
Sbjct: 346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAG 388
Score = 31.1 bits (67), Expect = 2.4
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 1/73 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C T G+ S C G SC T + +C+C GY G C + N CS
Sbjct: 342 CPTGTFGEDCGSTCPTCVQG-SCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCS 395
Query: 395 LHPCR-NGGTCKP 430
+ PC G C P
Sbjct: 396 V-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor class
F, member 1 protein.
Length = 830
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 31.9 bits (69), Expect = 1.4
Identities = 25/103 (24%), Positives = 34/103 (33%), Gaps = 1/103 (0%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVN 385
Q C G+ + C +G +C ++ +C C PG+ G CE P P
Sbjct: 295 QPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTG 345
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC + C C GY G SC G
Sbjct: 346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAG 388
Score = 31.1 bits (67), Expect = 2.4
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 1/73 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C T G+ S C G SC T + +C+C GY G C + N CS
Sbjct: 342 CPTGTFGEDCGSTCPTCVQG-SCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCS 395
Query: 395 LHPCR-NGGTCKP 430
+ PC G C P
Sbjct: 396 V-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein.
Length = 204
Score = 48.8 bits (111), Expect = 1e-05
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C R
Sbjct: 4 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARC---R 49
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ + C CP GY G +C++ L
Sbjct: 50 DRVHDFDCLCPSGYGGKTCELVL 72
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/38 (39%), Positives = 21/38 (55%)
Frame = +2
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ PC NG TC N + +C CP G+AG C + L+
Sbjct: 1 MRPCANGATCLDGINRF---SCLCPEGFAGRFCTINLD 35
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 42 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 78
>BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein.
Length = 204
Score = 48.8 bits (111), Expect = 1e-05
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +2
Query: 263 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C NG +C +C+CP G+ G +C + + C+ PC+ G C R
Sbjct: 4 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARC---R 49
Query: 437 NSWMNHTCDCPLGYAGASCQMPL 505
+ + C CP GY G +C++ L
Sbjct: 50 DRVHDFDCLCPSGYGGKTCELVL 72
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/38 (39%), Positives = 21/38 (55%)
Frame = +2
Query: 395 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ PC NG TC N + +C CP G+AG C + L+
Sbjct: 1 MRPCANGATCLDGINRF---SCLCPEGFAGRFCTINLD 35
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +2
Query: 263 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 379
C+ G C +C+CP GY G CE L P PP
Sbjct: 42 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 78
>AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein.
Length = 744
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 35.5 bits (78), Expect = 0.11
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Frame = +2
Query: 239 IQASESC-QCENGGSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+Q + SC +C++ CS ++ +C C PG+ G+ C+ C H CR+
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCP-H-CRH 315
Query: 413 GGTCKPD 433
G C+PD
Sbjct: 316 GEACEPD 322
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein.
Length = 337
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 36.3 bits (80), Expect = 0.065
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 239 IQASESC-QCENGGSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+Q + SC +C++ CS ++ +C C PG+ G+ C+ C H CR+
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCP-H-CRH 315
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAG 484
G C+PD H C G+ G
Sbjct: 316 GEACEPD----TGHCQRCDPGWLG 335
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein.
Length = 569
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 31.9 bits (69), Expect = 1.4
Identities = 25/103 (24%), Positives = 34/103 (33%), Gaps = 1/103 (0%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVN 385
Q C G+ + C +G +C ++ +C C PG+ G CE P P
Sbjct: 295 QPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTG 345
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC + C C GY G SC G
Sbjct: 346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAG 388
Score = 31.1 bits (67), Expect = 2.4
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 1/73 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C T G+ S C G SC T + +C+C GY G C + N CS
Sbjct: 342 CPTGTFGEDCGSTCPTCVQG-SCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCS 395
Query: 395 LHPCR-NGGTCKP 430
+ PC G C P
Sbjct: 396 V-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein.
Length = 342
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 36.3 bits (80), Expect = 0.065
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +2
Query: 239 IQASESC-QCENGGSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 412
+Q + SC +C++ CS ++ +C C PG+ G+ C+ C H CR+
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCP-H-CRH 315
Query: 413 GGTCKPDRNSWMNHTCDCPLGYAG 484
G C+PD H C G+ G
Sbjct: 316 GEACEPD----TGHCQRCDPGWLG 335
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein.
Length = 830
Score = 48.8 bits (111), Expect = 1e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +2
Query: 257 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 415
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 3e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 422 CKPDRNSWMNHTCD-CPLGYAGASCQMP 502
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 39.1 bits (87), Expect = 0.009
Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 5/115 (4%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRI 349
+S S+ +Q C + + D + + CE +C + C C PG+ G++C +R
Sbjct: 32 ASSPSAELQCCAGWRQKDQECTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRC 90
Query: 350 ASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
P C PC G C+P + C C GA C+ P G
Sbjct: 91 PGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRWGARCEFPCACG 136
Score = 31.9 bits (69), Expect = 1.4
Identities = 25/103 (24%), Positives = 34/103 (33%), Gaps = 1/103 (0%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVN 385
Q C G+ + C +G +C ++ +C C PG+ G CE P P
Sbjct: 295 QPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTG 345
Query: 386 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
TC + C C GY G SC G
Sbjct: 346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAG 388
Score = 31.1 bits (67), Expect = 2.4
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 1/73 (1%)
Frame = +2
Query: 215 CNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 394
C T G+ S C G SC T + +C+C GY G C + N CS
Sbjct: 342 CPTGTFGEDCGSTCPTCVQG-SCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCS 395
Query: 395 LHPCR-NGGTCKP 430
+ PC G C P
Sbjct: 396 V-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 4.3
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 430
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 431 DRNSWMNHTC--DCPLGYAGASCQ 496
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ25943 fis, clone JTH10559. ).
Length = 320
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG T +C CPPG+ G+ C P N C NGG C DR
Sbjct: 36 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGLC--DR-- 87
Query: 443 WMNHTCDCPLGYAGASCQMPLELGQ 517
C C GY G C+ +G+
Sbjct: 88 -FTGQCRCAPGYTGDRCREECPVGR 111
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/83 (32%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Frame = +2
Query: 248 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
S+ C+C NGG C + C C PGYTG C PV C C
Sbjct: 74 SQECRCHNGGLCDRFTGQCRCAPGYTGDRCREEC---------PVGRFG-QDCAETCDCA 123
Query: 428 PDRNSW-MNHTCDCPLGYAGASC 493
PD + N C C G+ G C
Sbjct: 124 PDARCFPANGACLCEHGFTGDRC 146
Score = 41.1 bits (92), Expect = 0.002
Identities = 22/57 (38%), Positives = 25/57 (43%)
Frame = +2
Query: 251 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
E C C +GG C S C C PGYTG +C + PPP P P G T
Sbjct: 207 EHCLCLHGGVCQATSGLCQCAPGYTGPHCASLC-------PPPRRPRRFLPQAAGET 256
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/95 (27%), Positives = 37/95 (38%)
Frame = +2
Query: 209 QECNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 388
+EC G +E+C C C + C+C G+TG C R+ P
Sbjct: 105 EECPVGRFGQ-DCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 163
Query: 389 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 493
C+ + +C P MN C C G+AG C
Sbjct: 164 CTCDR-EHSLSCHP-----MNGECSCLPGWAGLHC 192
Score = 36.7 bits (81), Expect = 0.049
Identities = 16/41 (39%), Positives = 21/41 (51%)
Frame = +2
Query: 392 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 514
S HPC+NGG + + S C CP G+ G C +P G
Sbjct: 32 STHPCQNGGVFQTPQGS-----CSCPPGWMGTICSLPCPEG 67
>BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1
protein.
Length = 379
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/88 (35%), Positives = 37/88 (42%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+A+ S C NGG+C CICPPG G CE ++ C PCRNGG
Sbjct: 243 KANCSTTCFNGGTCFYPG-KCICPPGLEGEQCE-------------ISKCP-QPCRNGGK 287
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C C C GY G C P+
Sbjct: 288 CIG------KSKCKCSKGYQGDLCSKPV 309
Score = 36.7 bits (81), Expect = 0.049
Identities = 26/77 (33%), Positives = 32/77 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C NGG C+ E C CP G+ G +CE L +P C NGG C
Sbjct: 186 CRNGGFCN-ERRICECPDGFHGPHCE----KALCTP----------RCMNGGLCVTP--- 227
Query: 443 WMNHTCDCPLGYAGASC 493
C CP G+ G +C
Sbjct: 228 ---GFCICPPGFYGVNC 241
>AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein.
Length = 379
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/88 (35%), Positives = 37/88 (42%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+A+ S C NGG+C CICPPG G CE ++ C PCRNGG
Sbjct: 243 KANCSTTCFNGGTCFYPG-KCICPPGLEGEQCE-------------ISKCP-QPCRNGGK 287
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C C C GY G C P+
Sbjct: 288 CIG------KSKCKCSKGYQGDLCSKPV 309
Score = 36.7 bits (81), Expect = 0.049
Identities = 26/77 (33%), Positives = 32/77 (41%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C NGG C+ E C CP G+ G +CE L +P C NGG C
Sbjct: 186 CRNGGFCN-ERRICECPDGFHGPHCE----KALCTP----------RCMNGGLCVTP--- 227
Query: 443 WMNHTCDCPLGYAGASC 493
C CP G+ G +C
Sbjct: 228 ---GFCICPPGFYGVNC 241
>AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1
protein.
Length = 379
Score = 48.0 bits (109), Expect = 2e-05
Identities = 31/88 (35%), Positives = 37/88 (42%)
Frame = +2
Query: 242 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 421
+A+ S C NGG+C CICPPG G CE ++ C PCRNGG
Sbjct: 243 KANCSTTCFNGGTCFYPG-KCICPPGLEGEQCE-------------ISKCP-QPCRNGGK 287
Query: 422 CKPDRNSWMNHTCDCPLGYAGASCQMPL 505
C C C GY G C P+
Sbjct: 288 CIG------KSKCKCSKGYQGDLCSKPV 309
Score = 37.1 bits (82), Expect = 0.037
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +2
Query: 239 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 418
+QA C NGG C+ E C CP G+ G +CE L +P C NGG
Sbjct: 178 LQAECPGGCRNGGFCN-ERRICECPDGFHGPHCE----KALCTP----------RCMNGG 222
Query: 419 TCKPDRNSWMNHTCDCPLGYAGASC 493
C C CP G+ G +C
Sbjct: 223 LCVTP------GFCICPPGFYGVNC 241
>AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein.
Length = 1321
Score = 48.0 bits (109), Expect = 2e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E+ C +GG+C+ T C C G+ G CE I + C PC NGGTC
Sbjct: 1013 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDI-----------DDCLCSPCENGGTC 1061
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ N ++ C C Y G+ C+ E
Sbjct: 1062 IDEVNGFV---CLCLPSYGGSFCEKDTE 1086
Score = 40.3 bits (90), Expect = 0.004
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC +PC +GGTC + N M + C C G+AG +C++ ++
Sbjct: 1010 DPCENNPCLHGGTC--NANGTM-YGCSCDQGFAGENCEIDID 1048
Score = 38.7 bits (86), Expect = 0.012
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
DI CENGG+C E C+C P Y GS+CE
Sbjct: 1046 DIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCE 1082
>AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS
protein.
Length = 315
Score = 48.0 bits (109), Expect = 2e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E+ C +GG+C+ T C C G+ G CE I + C PC NGGTC
Sbjct: 7 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDI-----------DDCLCSPCENGGTC 55
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ N ++ C C Y G+ C+ E
Sbjct: 56 IDEVNGFV---CLCLPSYGGSFCEKDTE 80
Score = 40.3 bits (90), Expect = 0.004
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC +PC +GGTC + N M + C C G+AG +C++ ++
Sbjct: 4 DPCENNPCLHGGTC--NANGTM-YGCSCDQGFAGENCEIDID 42
Score = 38.7 bits (86), Expect = 0.012
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
DI CENGG+C E C+C P Y GS+CE
Sbjct: 40 DIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCE 76
>AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein
protein.
Length = 1335
Score = 48.0 bits (109), Expect = 2e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +2
Query: 251 ESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
E+ C +GG+C+ T C C G+ G CE I + C PC NGGTC
Sbjct: 1027 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDI-----------DDCLCSPCENGGTC 1075
Query: 425 KPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+ N ++ C C Y G+ C+ E
Sbjct: 1076 IDEVNGFV---CLCLPSYGGSFCEKDTE 1100
Score = 40.3 bits (90), Expect = 0.004
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +2
Query: 383 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PC +PC +GGTC + N M + C C G+AG +C++ ++
Sbjct: 1024 DPCENNPCLHGGTC--NANGTM-YGCSCDQGFAGENCEIDID 1062
Score = 38.7 bits (86), Expect = 0.012
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 340
DI CENGG+C E C+C P Y GS+CE
Sbjct: 1060 DIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCE 1096
>AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain
containing protein protein.
Length = 199
Score = 47.2 bits (107), Expect = 3e-05
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL- 397
+I +S C NGG C EST C+CPP YTG +C R N C L
Sbjct: 15 EINECDSDPCMNGGLCH-ESTIPGQFVCLCPPLYTGQFCHQR-----------YNLCDLL 62
Query: 398 -HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
+PCRN TC ++ N C C + G +C++ ++
Sbjct: 63 HNPCRNNSTCLALVDA--NQHCICREEFEGKNCEIDVK 98
Score = 43.6 bits (98), Expect = 4e-04
Identities = 27/88 (30%), Positives = 38/88 (43%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 415
D++ C++ G C N PG++GS CE I N CS PC+N
Sbjct: 96 DVKDCLFLSCQDYGDCEDMVNNF--RPGFSGSLCEIEI-----------NECSSEPCKNN 142
Query: 416 GTCKPDRNSWMNHTCDCPLGYAGASCQM 499
GTC N + C+C Y G C++
Sbjct: 143 GTCVDLTNRFF---CNCEPEYHGPFCEL 167
Score = 34.7 bits (76), Expect = 0.20
Identities = 22/70 (31%), Positives = 24/70 (34%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 481
C C G+TG C I N C PC NGG C + C CP Y
Sbjct: 1 CECTSGWTGQNCSEEI-----------NECDSDPCMNGGLCH-ESTIPGQFVCLCPPLYT 48
Query: 482 GASCQMPLEL 511
G C L
Sbjct: 49 GQFCHQRYNL 58
Score = 34.3 bits (75), Expect = 0.26
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +2
Query: 236 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 406
+I S C+N G+C + TN C C P Y G +CE VN C + PC
Sbjct: 130 EINECSSEPCKNNGTC-VDLTNRFFCNCEPEYHGPFCEL-----------DVNKCKISPC 177
Query: 407 RNGGTCKPDRNSWMNHTCDCPLGY 478
+ C + + C C GY
Sbjct: 178 LDEENCVYRTD---GYNCLCAPGY 198
>X73902-1|CAA52108.1| 1193|Homo sapiens nicein protein.
Length = 1193
Score = 46.8 bits (106), Expect = 5e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRN 412
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.001
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>U31201-1|AAC50457.1| 1193|Homo sapiens laminin gamma2 chain
protein.
Length = 1193
Score = 46.8 bits (106), Expect = 5e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRN 412
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.001
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>U31200-1|AAC50456.1| 1111|Homo sapiens alternatively spliced
laminin gamma2 chain protein.
Length = 1111
Score = 46.8 bits (106), Expect = 5e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRN 412
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.001
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>BC113378-1|AAI13379.1| 1111|Homo sapiens laminin, gamma 2 protein.
Length = 1111
Score = 46.8 bits (106), Expect = 5e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRN 412
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.001
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>BC112286-1|AAI12287.1| 1111|Homo sapiens laminin, gamma 2 protein.
Length = 1111
Score = 46.8 bits (106), Expect = 5e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRN 412
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.001
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>AL354953-2|CAH70980.1| 1193|Homo sapiens laminin, gamma 2 protein.
Length = 1193
Score = 46.8 bits (106), Expect = 5e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRN 412
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.001
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein
protein.
Length = 1323
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 1228 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 1269
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 1270 ---YQCDCPPGWTGSRC 1283
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 1260 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 1304
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 1305 HCLSSWTGHNC 1315
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 1217 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 1255
>BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein
protein.
Length = 1441
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 1346 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 1387
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 1388 ---YQCDCPPGWTGSRC 1401
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 1378 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 1422
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 1423 HCLSSWTGHNC 1433
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 1335 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 1373
>AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing
protein protein.
Length = 1497
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 1402 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 1443
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 1444 ---YQCDCPPGWTGSRC 1457
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 1434 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 1478
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 1479 HCLSSWTGHNC 1489
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 1391 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 1429
>AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 1497
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 1402 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 1443
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 1444 ---YQCDCPPGWTGSRC 1457
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 1434 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 1478
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 1479 HCLSSWTGHNC 1489
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 1391 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 1429
>AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens cDNA
FLJ90754 fis, clone PLACE4000354, weakly similar to
COMPLEMENT RECEPTOR TYPE 1 PRECURSOR. ).
Length = 1497
Score = 46.4 bits (105), Expect = 6e-05
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 1402 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 1443
Query: 443 WMNHTCDCPLGYAGASC 493
+ CDCP G+ G+ C
Sbjct: 1444 ---YQCDCPPGWTGSRC 1457
Score = 46.0 bits (104), Expect = 8e-05
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 436
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 1434 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 1478
Query: 437 ---NSWMNHTC 460
+SW H C
Sbjct: 1479 HCLSSWTGHNC 1489
Score = 34.3 bits (75), Expect = 0.26
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +2
Query: 371 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 505
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 1391 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 1429
>AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.
Length = 1736
Score = 46.4 bits (105), Expect = 6e-05
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Frame = +2
Query: 257 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 427
C C + G C T S C+C G+TG+ C+T+ + P PCS H TCK
Sbjct: 1197 CGCSDHGQCDDGITGSGQCLCETGWTGTSCDTQAVLPAVCTP----PCSAH-----ATCK 1247
Query: 428 PDRNSWMNHTCDCPLGYAG 484
N+TC+C L Y G
Sbjct: 1248 E------NNTCECNLDYEG 1260
>Z15009-1|CAA78729.1| 1111|Homo sapiens Laminin protein.
Length = 1111
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/76 (38%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRNGGTCKP 430
PC PC+ P
Sbjct: 512 RPC--QPCQCNSNVDP 525
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVIP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC + G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>Z15008-1|CAA78728.1| 1193|Homo sapiens Laminin protein.
Length = 1193
Score = 46.0 bits (104), Expect = 8e-05
Identities = 29/76 (38%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Frame = +2
Query: 227 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 382
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 383 NPCSLHPCRNGGTCKP 430
PC PC+ P
Sbjct: 512 RPC--QPCQCNSNVDP 525
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +2
Query: 302 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 454
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 455 TCDCPLGY 478
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.001
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 436
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVIP 474
Query: 437 NSWMNHTCDCPLGYAGASCQM 499
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 39.9 bits (89), Expect = 0.005
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 379
+ G ++ + CQC + G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 1.4
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +2
Query: 257 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 364
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.
Length = 4655
Score = 46.0 bits (104), Expect = 8e-05
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCE 340
SS + EC+ I C+C +GG+C + T+ C CP GYTG YCE
Sbjct: 4357 SSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 4411
Score = 39.9 bits (89), Expect = 0.005
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 3/77 (3%)
Frame = +2
Query: 299 NCICPPGYT---GSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
+C CP G + GS E A L PP PC C +GG C D C CP
Sbjct: 4350 SCACPQGSSFIEGSTTECDAAIELPINLPP--PCR---CMHGGNCYFDETDLPK--CKCP 4402
Query: 470 LGYAGASCQMPLELGQS 520
GY G C+M G S
Sbjct: 4403 SGYTGKYCEMAFSKGIS 4419
>U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein.
Length = 1751
Score = 46.0 bits (104), Expect = 8e-05
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCE 340
SS + EC+ I C+C +GG+C + T+ C CP GYTG YCE
Sbjct: 1655 SSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 1709
Score = 39.9 bits (89), Expect = 0.005
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 3/77 (3%)
Frame = +2
Query: 299 NCICPPGYT---GSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
+C CP G + GS E A L PP PC C +GG C D C CP
Sbjct: 1648 SCACPQGSSFIEGSTTECDAAIELPINLPP--PCR---CMHGGNCYFDETDLPK--CKCP 1700
Query: 470 LGYAGASCQMPLELGQS 520
GY G C+M G S
Sbjct: 1701 SGYTGKYCEMAFSKGIS 1717
>L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 1124
Score = 46.0 bits (104), Expect = 8e-05
Identities = 22/77 (28%), Positives = 30/77 (38%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C N G C ++ CICPPG+ G CE + C++ C PD
Sbjct: 227 CMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPD--- 283
Query: 443 WMNHTCDCPLGYAGASC 493
+ C C G+ G C
Sbjct: 284 --PYGCSCATGWKGLQC 298
Score = 33.1 bits (72), Expect = 0.61
Identities = 12/28 (42%), Positives = 14/28 (50%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C C NG C C+C PG+ G CE
Sbjct: 315 CSCNNGEMCD-RFQGCLCSPGWQGLQCE 341
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/36 (36%), Positives = 16/36 (44%)
Frame = +2
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C N G C D C CP G+ G +C+ EL
Sbjct: 227 CMNNGVCHEDTGE-----CICPPGFMGRTCEKACEL 257
>BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous
and protein.
Length = 1124
Score = 46.0 bits (104), Expect = 8e-05
Identities = 22/77 (28%), Positives = 30/77 (38%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C N G C ++ CICPPG+ G CE + C++ C PD
Sbjct: 227 CMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPD--- 283
Query: 443 WMNHTCDCPLGYAGASC 493
+ C C G+ G C
Sbjct: 284 --PYGCSCATGWKGLQC 298
Score = 33.1 bits (72), Expect = 0.61
Identities = 12/28 (42%), Positives = 14/28 (50%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C C NG C C+C PG+ G CE
Sbjct: 315 CSCNNGEMCD-RFQGCLCSPGWQGLQCE 341
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/36 (36%), Positives = 16/36 (44%)
Frame = +2
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C N G C D C CP G+ G +C+ EL
Sbjct: 227 CMNNGVCHEDTGE-----CICPPGFMGRTCEKACEL 257
>AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor
gp330/megalin precursor protein.
Length = 4655
Score = 46.0 bits (104), Expect = 8e-05
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCE 340
SS + EC+ I C+C +GG+C + T+ C CP GYTG YCE
Sbjct: 4357 SSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 4411
Score = 39.9 bits (89), Expect = 0.005
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 3/77 (3%)
Frame = +2
Query: 299 NCICPPGYT---GSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
+C CP G + GS E A L PP PC C +GG C D C CP
Sbjct: 4350 SCACPQGSSFIEGSTTECDAAIELPINLPP--PCR---CMHGGNCYFDETDLPK--CKCP 4402
Query: 470 LGYAGASCQMPLELGQS 520
GY G C+M G S
Sbjct: 4403 SGYTGKYCEMAFSKGIS 4419
>AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor
gp330/megalin precursor protein.
Length = 4655
Score = 46.0 bits (104), Expect = 8e-05
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCE 340
SS + EC+ I C+C +GG+C + T+ C CP GYTG YCE
Sbjct: 4357 SSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 4411
Score = 39.9 bits (89), Expect = 0.005
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 3/77 (3%)
Frame = +2
Query: 299 NCICPPGYT---GSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
+C CP G + GS E A L PP PC C +GG C D C CP
Sbjct: 4350 SCACPQGSSFIEGSTTECDAAIELPINLPP--PCR---CMHGGNCYFDETDLPK--CKCP 4402
Query: 470 LGYAGASCQMPLELGQS 520
GY G C+M G S
Sbjct: 4403 SGYTGKYCEMAFSKGIS 4419
>AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA
sequence from clone RP11-307F22 on chromosome 6. ).
Length = 186
Score = 46.0 bits (104), Expect = 8e-05
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
Frame = +2
Query: 140 CIKDVVLNSNAVD-INSSIKSSNIQECNTYDRGDIQASESCQCENGGSC--STESTNCIC 310
C+ + L+ + IN S + +T + I S C N G C S CIC
Sbjct: 86 CLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCIC 145
Query: 311 PPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 424
P GYTG+YCE I + P +N C NGG C
Sbjct: 146 PRGYTGAYCEKSIDN---CAEPELNSVI---CLNGGIC 177
Score = 44.4 bits (100), Expect = 2e-04
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 12/97 (12%)
Frame = +2
Query: 254 SCQCENG--GS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNPCSL 397
+C C++G G+ C T + +C+ P G C I Y S +N C+
Sbjct: 67 TCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTS 125
Query: 398 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 508
PC N G C+ + + TC CP GY GA C+ ++
Sbjct: 126 IPCMNEGFCQKSAHGF---TCICPRGYTGAYCEKSID 159
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/39 (33%), Positives = 20/39 (51%)
Frame = +2
Query: 380 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 496
++ C PC + G C N ++TCDC G+ G C+
Sbjct: 45 LDECLSEPCLHDGVCIDGIN---HYTCDCKSGFFGTHCE 80
>AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous
and protein.
Length = 1124
Score = 46.0 bits (104), Expect = 8e-05
Identities = 22/77 (28%), Positives = 30/77 (38%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C N G C ++ CICPPG+ G CE + C++ C PD
Sbjct: 227 CMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPD--- 283
Query: 443 WMNHTCDCPLGYAGASC 493
+ C C G+ G C
Sbjct: 284 --PYGCSCATGWKGLQC 298
Score = 33.1 bits (72), Expect = 0.61
Identities = 12/28 (42%), Positives = 14/28 (50%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C C NG C C+C PG+ G CE
Sbjct: 315 CSCNNGEMCD-RFQGCLCSPGWQGLQCE 341
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/36 (36%), Positives = 16/36 (44%)
Frame = +2
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C N G C D C CP G+ G +C+ EL
Sbjct: 227 CMNNGVCHEDTGE-----CICPPGFMGRTCEKACEL 257
>AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein.
Length = 3881
Score = 46.0 bits (104), Expect = 8e-05
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Frame = +2
Query: 185 SSIKSSNIQECNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCE 340
SS + EC+ I C+C +GG+C + T+ C CP GYTG YCE
Sbjct: 3583 SSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCE 3637
Score = 39.9 bits (89), Expect = 0.005
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 3/77 (3%)
Frame = +2
Query: 299 NCICPPGYT---GSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 469
+C CP G + GS E A L PP PC C +GG C D C CP
Sbjct: 3576 SCACPQGSSFIEGSTTECDAAIELPINLPP--PCR---CMHGGNCYFDETDLPK--CKCP 3628
Query: 470 LGYAGASCQMPLELGQS 520
GY G C+M G S
Sbjct: 3629 SGYTGKYCEMAFSKGIS 3645
>AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase
variant protein.
Length = 1157
Score = 46.0 bits (104), Expect = 8e-05
Identities = 22/77 (28%), Positives = 30/77 (38%)
Frame = +2
Query: 263 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 442
C N G C ++ CICPPG+ G CE + C++ C PD
Sbjct: 260 CMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPD--- 316
Query: 443 WMNHTCDCPLGYAGASC 493
+ C C G+ G C
Sbjct: 317 --PYGCSCATGWKGLQC 331
Score = 33.1 bits (72), Expect = 0.61
Identities = 12/28 (42%), Positives = 14/28 (50%)
Frame = +2
Query: 257 CQCENGGSCSTESTNCICPPGYTGSYCE 340
C C NG C C+C PG+ G CE
Sbjct: 348 CSCNNGEMCD-RFQGCLCSPGWQGLQCE 374
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/36 (36%), Positives = 16/36 (44%)
Frame = +2
Query: 404 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 511
C N G C D C CP G+ G +C+ EL
Sbjct: 260 CMNNGVCHEDTGE-----CICPPGFMGRTCEKACEL 290
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 81,326,092
Number of Sequences: 237096
Number of extensions: 1932671
Number of successful extensions: 17419
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8751
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13777
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -