Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS324E02f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 151 1e-36
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 151 1e-36
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 151 1e-36
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 151 1e-36
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 151 1e-36
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 151 1e-36
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 151 1e-36
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 129 5e-30
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 129 7e-30
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 129 7e-30
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 129 7e-30
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 118 9e-27
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 118 9e-27
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 112 8e-25
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 112 8e-25
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 112 8e-25
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 112 8e-25
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 112 8e-25
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 112 8e-25
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 111 1e-24
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 111 1e-24
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 111 1e-24
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 111 1e-24
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 111 1e-24
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 111 1e-24
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 111 1e-24
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 111 1e-24
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 111 1e-24
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 109 6e-24
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 109 6e-24
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 109 6e-24
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 109 6e-24
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 109 6e-24
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 109 6e-24
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 109 6e-24
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 109 6e-24
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 109 6e-24
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 107 2e-23
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 5e-09
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 58 2e-08
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 50 5e-06
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 50 5e-06
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 50 5e-06
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 50 5e-06
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 50 5e-06
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 50 5e-06
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 50 5e-06
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 50 5e-06
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 50 5e-06
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 50 5e-06
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 50 5e-06
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 47 3e-05
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.012
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 37 0.037
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 37 0.037
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 37 0.037
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 37 0.037
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 37 0.037
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 37 0.037
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 37 0.037
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 37 0.037
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 37 0.037
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 37 0.037
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 37 0.037
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 37 0.037
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 37 0.037
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 37 0.049
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.20
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 33 0.46
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 3.2
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 4.3
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 4.3
AK096194-1|BAC04723.1| 138|Homo sapiens protein ( Homo sapiens ... 30 5.7
BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein. 24 7.1
BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein. 24 7.1
AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosph... 24 7.1
AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens ... 24 7.4
BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19 ... 29 7.5
AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein pr... 29 7.5
AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens ... 29 7.5
AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens ... 29 7.5
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 151 bits (366), Expect = 1e-36
Identities = 78/140 (55%), Positives = 91/140 (65%), Gaps = 11/140 (7%)
Frame = +3
Query: 135 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 281
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 462 YVANGTQFAIQYGSGSLSGF 521
YV NGT F I YGSGSLSG+
Sbjct: 131 YVKNGTSFDIHYGSGSLSGY 150
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 129 bits (312), Expect = 5e-30
Identities = 61/130 (46%), Positives = 85/130 (65%), Gaps = 5/130 (3%)
Frame = +3
Query: 144 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 308
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 309 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 488
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 489 IQYGSGSLSG 518
IQYG+G + G
Sbjct: 139 IQYGTGRVDG 148
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 129 bits (311), Expect = 7e-30
Identities = 61/130 (46%), Positives = 85/130 (65%), Gaps = 5/130 (3%)
Frame = +3
Query: 144 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 308
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 309 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 488
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 489 IQYGSGSLSG 518
IQYG+G + G
Sbjct: 139 IQYGTGRVDG 148
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 129 bits (311), Expect = 7e-30
Identities = 61/130 (46%), Positives = 85/130 (65%), Gaps = 5/130 (3%)
Frame = +3
Query: 144 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 308
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 309 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 488
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 489 IQYGSGSLSG 518
IQYG+G + G
Sbjct: 139 IQYGTGRVDG 148
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 129 bits (311), Expect = 7e-30
Identities = 61/130 (46%), Positives = 85/130 (65%), Gaps = 5/130 (3%)
Frame = +3
Query: 144 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 308
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 309 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 488
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 489 IQYGSGSLSG 518
IQYG+G + G
Sbjct: 139 IQYGTGRVDG 148
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 118 bits (285), Expect = 9e-27
Identities = 55/123 (44%), Positives = 80/123 (65%), Gaps = 5/123 (4%)
Frame = +3
Query: 165 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 329
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 330 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 509
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 510 LSG 518
+ G
Sbjct: 142 VDG 144
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 118 bits (285), Expect = 9e-27
Identities = 55/123 (44%), Positives = 80/123 (65%), Gaps = 5/123 (4%)
Frame = +3
Query: 165 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 329
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 330 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 509
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 510 LSG 518
+ G
Sbjct: 146 VDG 148
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 112 bits (269), Expect = 8e-25
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 315 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 494
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 495 YGSGSLSGF 521
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 112 bits (269), Expect = 8e-25
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 315 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 494
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 495 YGSGSLSGF 521
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 112 bits (269), Expect = 8e-25
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 315 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 494
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 495 YGSGSLSGF 521
YGSGSL+GF
Sbjct: 131 YGSGSLTGF 139
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 112 bits (269), Expect = 8e-25
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 315 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 494
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 495 YGSGSLSGF 521
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 112 bits (269), Expect = 8e-25
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 315 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 494
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 495 YGSGSLSGF 521
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 112 bits (269), Expect = 8e-25
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 315 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 494
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 495 YGSGSLSGF 521
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 111 bits (267), Expect = 1e-24
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 282 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 461
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 462 YVANGTQFAIQYGSGSLSGF 521
Y NGT+ ++Y +G++SGF
Sbjct: 138 YKHNGTELTLRYSTGTVSGF 157
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 109 bits (262), Expect = 6e-24
Identities = 61/143 (42%), Positives = 82/143 (57%), Gaps = 12/143 (8%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 275
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 276 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 449
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 450 KSKTYVANGTQFAIQYGSGSLSG 518
S TY + +I YG+GS++G
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTG 144
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 109 bits (262), Expect = 6e-24
Identities = 61/143 (42%), Positives = 82/143 (57%), Gaps = 12/143 (8%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 275
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 276 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 449
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 450 KSKTYVANGTQFAIQYGSGSLSG 518
S TY + +I YG+GS++G
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTG 144
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 109 bits (262), Expect = 6e-24
Identities = 61/141 (43%), Positives = 84/141 (59%), Gaps = 10/141 (7%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 275
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 276 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 456 KTYVANGTQFAIQYGSGSLSG 518
TY G F+IQYG+GSLSG
Sbjct: 126 STYSQPGQSFSIQYGTGSLSG 146
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 107 bits (258), Expect = 2e-23
Identities = 60/143 (41%), Positives = 82/143 (57%), Gaps = 12/143 (8%)
Frame = +3
Query: 126 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 275
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 276 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 449
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 450 KSKTYVANGTQFAIQYGSGSLSG 518
S TY + +I YG+GS++G
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTG 144
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 5e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +3
Query: 162 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 314
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 315 VISIGTPPQSFKVVFDTGSSNL 380
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 57.6 bits (133), Expect = 2e-08
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +3
Query: 372 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGF 521
SN+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGF
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGF 50
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 67 TVKYTQGSWTGF 78
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 50.0 bits (114), Expect = 5e-06
Identities = 26/72 (36%), Positives = 38/72 (52%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 486 AIQYGSGSLSGF 521
++Y GS +GF
Sbjct: 146 TVKYTQGSWTGF 157
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 47.2 bits (107), Expect = 3e-05
Identities = 24/66 (36%), Positives = 35/66 (53%)
Frame = +3
Query: 324 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGS 503
IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 504 GSLSGF 521
GS +GF
Sbjct: 57 GSWTGF 62
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +3
Query: 153 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 305
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 306 YYGVISIGTP 335
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 116 YVPYTQGKWEG 126
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 129 YVPYTQGKWEG 139
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 37.1 bits (82), Expect = 0.037
Identities = 22/71 (30%), Positives = 33/71 (46%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 485
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 486 AIQYGSGSLSG 518
+ Y G G
Sbjct: 160 YVPYTQGKWEG 170
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.7 bits (81), Expect = 0.049
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 464
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.20
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 306 YYGVISIGTPPQSFKVVFDTGSSNLWV 386
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 33.5 bits (73), Expect = 0.46
Identities = 18/58 (31%), Positives = 29/58 (50%)
Frame = +3
Query: 348 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGF 521
+++ DTGSSN V Y + +D+ +S TY + G ++Y GS +GF
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGF 54
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 3.2
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 371 GSGVEYHLERLRRRADTDHSVVLSIK 294
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 4.3
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -3
Query: 297 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 145
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 4.3
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -3
Query: 444 CRTCCAANKRCWCSGTFWKAPRGWRIR 364
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 4.3
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -3
Query: 297 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 145
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 4.3
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -3
Query: 444 CRTCCAANKRCWCSGTFWKAPRGWRIR 364
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK096194-1|BAC04723.1| 138|Homo sapiens protein ( Homo sapiens
cDNA FLJ38875 fis, clone MESAN2013936. ).
Length = 138
Score = 29.9 bits (64), Expect = 5.7
Identities = 14/45 (31%), Positives = 19/45 (42%)
Frame = -3
Query: 507 CRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCSGTFWKAPRGW 373
C S T C R + C +CC + + C CS T+W W
Sbjct: 75 CLSEEAGETAC--RASPGQCYVTSCCLS-RHCTCSLTWWDVLLNW 116
>BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 7.1
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 450 CGCRTCCAANKRC 412
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 7.1
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 483 TGCHSRRTSWTCGCRTCCAA 424
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 7.1
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 450 CGCRTCCAANKRC 412
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 7.1
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 483 TGCHSRRTSWTCGCRTCCAA 424
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosphate
transporter isoform NaPi-IIb protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 7.1
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 450 CGCRTCCAANKRC 412
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 7.1
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 483 TGCHSRRTSWTCGCRTCCAA 424
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens
cDNA FLJ90534 fis, clone OVARC1000003, highly similar to
Homo sapiens sodium dependent phosphate transporter
isoform ).
Length = 397
Score = 24.2 bits (50), Expect(2) = 7.4
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 450 CGCRTCCAANKRC 412
CGC CC +K C
Sbjct: 340 CGCPKCCRCSKCC 352
Score = 23.8 bits (49), Expect(2) = 7.4
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 483 TGCHSRRTSWTCGCRTCCAA 424
TGC R C CR CC A
Sbjct: 318 TGCFQMRCC--CCCRVCCRA 335
>BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19
protein.
Length = 458
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 303 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 187
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 137 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 175
>AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein
protein.
Length = 339
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 303 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 187
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 18 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 56
>AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ32768 fis, clone TESTI2001879, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 303 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 187
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ31005 fis, clone HLUNG2000068, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 303 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 187
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,878,874
Number of Sequences: 237096
Number of extensions: 1669063
Number of successful extensions: 3555
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 3345
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3516
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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