Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS320E12f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 142 9e-34
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 142 9e-34
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 142 9e-34
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 142 9e-34
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 142 9e-34
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 140 4e-33
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 140 4e-33
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 122 8e-28
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 122 8e-28
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 122 8e-28
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 121 1e-27
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 120 4e-27
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 120 4e-27
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 120 4e-27
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 120 4e-27
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 120 4e-27
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 119 5e-27
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 119 5e-27
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 119 5e-27
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 119 5e-27
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 119 5e-27
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 119 5e-27
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 119 5e-27
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 119 5e-27
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 114 2e-25
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 114 2e-25
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 114 2e-25
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 114 2e-25
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 114 2e-25
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 113 3e-25
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 113 5e-25
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 113 5e-25
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 113 5e-25
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 113 5e-25
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 113 5e-25
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 113 5e-25
AL132795-7|CAI20502.1| 121|Homo sapiens karyopherin alpha 5 (im... 72 1e-12
AL135901-9|CAI40722.1| 90|Homo sapiens karyopherin alpha 3 (im... 70 6e-12
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 56 6e-08
AF036977-1|AAD02090.1| 331|Homo sapiens unknown protein. 34 0.35
BC068549-1|AAH68549.1| 862|Homo sapiens LOC100101438 protein pr... 33 0.80
AL365510-1|CAM19360.1| 862|Homo sapiens Novel protein similar t... 33 0.80
X92493-1|CAA63224.1| 540|Homo sapiens STM-7 protein. 32 1.4
U52387-1|AAC51327.1| 540|Homo sapiens STM7 protein. 32 1.4
BC030587-1|AAH30587.1| 549|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL356219-4|CAI14095.1| 540|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL356219-3|CAI14094.1| 162|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL356219-2|CAI14093.1| 157|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL356219-1|CAI14092.1| 103|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL354794-6|CAI12625.1| 540|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL354794-5|CAI12624.1| 162|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL354794-4|CAI12623.1| 157|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL354794-3|CAI12622.1| 103|Homo sapiens phosphatidylinositol-4-... 32 1.4
AL162730-3|CAH71831.1| 540|Homo sapiens phosphatidylinositol-4-... 32 1.4
U78577-1|AAC50912.1| 500|Homo sapiens 68 kDa type I phosphatidy... 31 1.9
U78576-1|AAC50911.1| 562|Homo sapiens 68 kDa type I phosphatidy... 31 1.9
U78575-1|AAC50910.1| 549|Homo sapiens 68 kDa type I phosphatidy... 31 1.9
BC007833-1|AAH07833.1| 500|Homo sapiens PIP5K1A protein protein. 31 1.9
AL592424-18|CAI16386.1| 562|Homo sapiens phosphatidylinositol-4... 31 1.9
AL592424-17|CAI16387.1| 549|Homo sapiens phosphatidylinositol-4... 31 1.9
AL592424-16|CAI16388.1| 500|Homo sapiens phosphatidylinositol-4... 31 1.9
BC028580-1|AAH28580.1| 512|Homo sapiens MGC26597 protein protein. 30 4.3
AY557347-1|AAS67921.1| 174|Homo sapiens unknown protein. 30 5.7
AY255147-6|AAO66805.1| 226|Homo sapiens ATP synthase F0 subunit... 30 5.7
AY017307-1|AAG52948.1| 3389|Homo sapiens CUB and sushi multiple ... 30 5.7
AK093877-1|BAC04239.1| 570|Homo sapiens protein ( Homo sapiens ... 29 7.5
AC004637-1|AAC15471.1| 156|Homo sapiens KIAA0589 protein. 29 7.5
AB011161-1|BAA25515.1| 687|Homo sapiens KIAA0589 protein protein. 29 7.5
BC051868-1|AAH51868.2| 741|Homo sapiens UBE2O protein protein. 29 9.9
BC036820-1|AAH36820.1| 1025|Homo sapiens UBE2O protein protein. 29 9.9
AK025999-1|BAB15313.1| 742|Homo sapiens protein ( Homo sapiens ... 29 9.9
AF271379-1|AAG49889.1| 1241|Homo sapiens interphotoreceptor matr... 29 9.9
AF173155-1|AAF06999.1| 1241|Homo sapiens interphotoreceptor matr... 29 9.9
AF157624-1|AAF13154.1| 1241|Homo sapiens Spacrcan protein. 29 9.9
AB051521-1|BAB21825.1| 1313|Homo sapiens KIAA1734 protein protein. 29 9.9
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 142 bits (343), Expect = 9e-34
Identities = 69/164 (42%), Positives = 100/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA K + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.3 bits (85), Expect = 0.016
Identities = 20/75 (26%), Positives = 37/75 (49%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHR 230
++ ++L D +
Sbjct: 378 LVPFLVSVLSKADFK 392
Score = 35.1 bits (77), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++A WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALLQARD 224
+ P ALL D
Sbjct: 204 GAVDPLLALLAVPD 217
Score = 32.3 bits (70), Expect = 1.1
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ A++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 142 bits (343), Expect = 9e-34
Identities = 69/164 (42%), Positives = 100/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA K + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.3 bits (85), Expect = 0.016
Identities = 20/75 (26%), Positives = 37/75 (49%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHR 230
++ ++L D +
Sbjct: 378 LVPFLVSVLSKADFK 392
Score = 35.1 bits (77), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++A WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALLQARD 224
+ P ALL D
Sbjct: 204 GAVDPLLALLAVPD 217
Score = 32.3 bits (70), Expect = 1.1
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ A++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 142 bits (343), Expect = 9e-34
Identities = 69/164 (42%), Positives = 100/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA K + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.3 bits (85), Expect = 0.016
Identities = 20/75 (26%), Positives = 37/75 (49%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHR 230
++ ++L D +
Sbjct: 378 LVPFLVSVLSKADFK 392
Score = 33.1 bits (72), Expect = 0.61
Identities = 17/74 (22%), Positives = 34/74 (45%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++ WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALLQARD 224
+ P ALL D
Sbjct: 204 GAVDPLLALLAVPD 217
Score = 32.3 bits (70), Expect = 1.1
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ A++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIRAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 142 bits (343), Expect = 9e-34
Identities = 69/164 (42%), Positives = 100/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA K + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.3 bits (85), Expect = 0.016
Identities = 20/75 (26%), Positives = 37/75 (49%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHR 230
++ ++L D +
Sbjct: 378 LVPFLVSVLSKADFK 392
Score = 33.9 bits (74), Expect = 0.35
Identities = 17/70 (24%), Positives = 34/70 (48%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++A WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALL 212
+ P ALL
Sbjct: 204 GAVDPLLALL 213
Score = 32.3 bits (70), Expect = 1.1
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ A++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 142 bits (343), Expect = 9e-34
Identities = 69/164 (42%), Positives = 100/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA K + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.3 bits (85), Expect = 0.016
Identities = 20/75 (26%), Positives = 37/75 (49%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHR 230
++ ++L D +
Sbjct: 378 LVPFLVSVLSKADFK 392
Score = 35.1 bits (77), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++A WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALLQARD 224
+ P ALL D
Sbjct: 204 GAVDPLLALLAVPD 217
Score = 32.3 bits (70), Expect = 1.1
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ A++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 140 bits (338), Expect = 4e-33
Identities = 68/164 (41%), Positives = 99/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAENLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.7 bits (86), Expect = 0.012
Identities = 29/141 (20%), Positives = 63/141 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHE 365
++ ++L D + + +T+ + +Q+ + L G ++ + NL +
Sbjct: 378 LVPFLVSVLSKADFKTQKEAVWAVTN-YTSGGTVEQI----VYLVHCGIIEPLMNLLTAK 432
Query: 366 NEQIYKKSIHILDSYFMEEED 428
+ +I + + + F E+
Sbjct: 433 DTKIILVILDAISNIFQAAEN 453
Score = 34.3 bits (75), Expect = 0.26
Identities = 18/74 (24%), Positives = 35/74 (47%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++A WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALLQARD 224
+ P ALL D
Sbjct: 204 GAVDPLLALLAVPD 217
Score = 30.7 bits (66), Expect = 3.2
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ ++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKVVVDGGAIPAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 140 bits (338), Expect = 4e-33
Identities = 68/164 (41%), Positives = 99/164 (60%), Gaps = 2/164 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ+ ++ G++ + VL D K QKEA WA+TN GGT EQ+ ++ C
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC 419
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
I+ P LL A+D + I+V+LD ++++ QAA + + I +EE G LD+IE LQ H
Sbjct: 420 GIIEPLMNLLTAKDTKIILVILDAISNIFQAAENLGETEKLSIMIEECGGLDKIEALQNH 479
Query: 363 ENEQIYKKSIHILDSYFM--EEEDASTQPAHDHEQYQFRTNDAA 488
ENE +YK S+ +++ YF EEED + P E Y F+ D A
Sbjct: 480 ENESVYKASLSLIEKYFSVEEEEDQNVVPETTSEGYTFQVQDGA 523
Score = 38.7 bits (86), Expect = 0.012
Identities = 29/141 (20%), Positives = 63/141 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ID+G L +L + QKEA W ++N+ G +Q+ +++
Sbjct: 319 NIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHG 377
Query: 186 ILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHE 365
++ ++L D + + +T+ + +Q+ + L G ++ + NL +
Sbjct: 378 LVPFLVSVLSKADFKTQKEAVWAVTN-YTSGGTVEQI----VYLVHCGIIEPLMNLLTAK 432
Query: 366 NEQIYKKSIHILDSYFMEEED 428
+ +I + + + F E+
Sbjct: 433 DTKIILVILDAISNIFQAAEN 453
Score = 34.3 bits (75), Expect = 0.26
Identities = 18/74 (24%), Positives = 35/74 (47%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT+ Q + +D G + +L ++A WA+ N+ G+ + D ++
Sbjct: 145 TNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR-DLVIKY 203
Query: 183 DILSPYCALLQARD 224
+ P ALL D
Sbjct: 204 GAVDPLLALLAVPD 217
Score = 30.7 bits (66), Expect = 3.2
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I +G++ L D Q E+AWA+TN+ GT EQ ++ + +
Sbjct: 110 PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKVVVDGGAIPAFI 168
Query: 204 ALL 212
+LL
Sbjct: 169 SLL 171
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 122 bits (294), Expect = 8e-28
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ +++
Sbjct: 364 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVAL 423
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGM-----CIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G+ C +EE LD+IE
Sbjct: 424 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIE 483
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +EE+D S P D Q QF
Sbjct: 484 FLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDENQQQF 525
Score = 38.7 bits (86), Expect = 0.012
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT + I++G + ++L Q++A WA+ N+ G E D +L+C
Sbjct: 153 TNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIA-GDNAECRDFVLNC 211
Query: 183 DILSPYCALL 212
+IL P LL
Sbjct: 212 EILPPLLELL 221
Score = 36.3 bits (80), Expect = 0.065
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 285 GPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALPC 343
Query: 198 YCALLQA 218
LL +
Sbjct: 344 LLHLLSS 350
Score = 31.5 bits (68), Expect = 1.9
Identities = 18/75 (24%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W ++N+ G Q+ A++ +
Sbjct: 323 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNI-TAGNRAQIQAVIDAN 381
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 382 IFPVLIEILQKAEFR 396
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 122 bits (294), Expect = 8e-28
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ +++
Sbjct: 364 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVAL 423
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGM-----CIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G+ C +EE LD+IE
Sbjct: 424 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIE 483
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +EE+D S P D Q QF
Sbjct: 484 FLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDENQQQF 525
Score = 38.7 bits (86), Expect = 0.012
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT + I++G + ++L Q++A WA+ N+ G E D +L+C
Sbjct: 153 TNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIA-GDNAECRDFVLNC 211
Query: 183 DILSPYCALL 212
+IL P LL
Sbjct: 212 EILPPLLELL 221
Score = 36.3 bits (80), Expect = 0.065
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 285 GPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALPC 343
Query: 198 YCALLQA 218
LL +
Sbjct: 344 LLHLLSS 350
Score = 31.5 bits (68), Expect = 1.9
Identities = 18/75 (24%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W ++N+ G Q+ A++ +
Sbjct: 323 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNI-TAGNRAQIQAVIDAN 381
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 382 IFPVLIEILQKAEFR 396
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 122 bits (294), Expect = 8e-28
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ +++
Sbjct: 361 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVAL 420
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGM-----CIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G+ C +EE LD+IE
Sbjct: 421 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIE 480
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +EE+D S P D Q QF
Sbjct: 481 FLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDENQQQF 522
Score = 38.7 bits (86), Expect = 0.012
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
+N+ +GT + I++G + ++L Q++A WA+ N+ G E D +L+C
Sbjct: 150 TNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIA-GDNAECRDFVLNC 208
Query: 183 DILSPYCALL 212
+IL P LL
Sbjct: 209 EILPPLLELL 218
Score = 36.3 bits (80), Expect = 0.065
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 282 GPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALPC 340
Query: 198 YCALLQA 218
LL +
Sbjct: 341 LLHLLSS 347
Score = 31.5 bits (68), Expect = 1.9
Identities = 18/75 (24%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W ++N+ G Q+ A++ +
Sbjct: 320 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNI-TAGNRAQIQAVIDAN 378
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 379 IFPVLIEILQKAEFR 393
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 121 bits (292), Expect = 1e-27
Identities = 59/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
D++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 DVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FQNLL 335
Score = 35.1 bits (77), Expect = 0.15
Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L +NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFQNLLSHPKEKINKEAVWFLSN 352
Score = 34.3 bits (75), Expect = 0.26
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.1 bits (72), Expect = 0.61
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLS 179
P I I SG+L + + L D Q EAAWA+TN+ G + + D + S
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQDIVQS 156
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 120 bits (288), Expect = 4e-27
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ ++S
Sbjct: 361 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSL 420
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQ-----VRGMCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + V C +EE LD+IE
Sbjct: 421 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIE 480
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +E++D+S P D Q QF
Sbjct: 481 FLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQF 522
Score = 41.1 bits (92), Expect = 0.002
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q + I++G + PI L++ D + Q++A WA+ N+ G + D +L+
Sbjct: 150 TNIASGTSQQTKIVIEAGAV-PIFIELLNSDFEDVQEQAVWALGNIA-GDSSVCRDYVLN 207
Query: 180 CDILSPYCALL 212
C IL+P LL
Sbjct: 208 CSILNPLLTLL 218
Score = 36.7 bits (81), Expect = 0.049
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPC 340
Query: 198 YCALLQA 218
LL +
Sbjct: 341 LLHLLSS 347
Score = 31.9 bits (69), Expect = 1.4
Identities = 19/75 (25%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W I+N+ G Q+ A++ +
Sbjct: 320 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDAN 378
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 379 IFPVLIEILQKAEFR 393
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 120 bits (288), Expect = 4e-27
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ ++S
Sbjct: 361 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSL 420
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQ-----VRGMCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + V C +EE LD+IE
Sbjct: 421 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIE 480
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +E++D+S P D Q QF
Sbjct: 481 FLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQF 522
Score = 41.1 bits (92), Expect = 0.002
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q + I++G + PI L++ D + Q++A WA+ N+ G + D +L+
Sbjct: 150 TNIASGTSQQTKIVIEAGAV-PIFIELLNSDFEDVQEQAVWALGNIA-GDSSVCRDYVLN 207
Query: 180 CDILSPYCALL 212
C IL+P LL
Sbjct: 208 CSILNPLLTLL 218
Score = 36.7 bits (81), Expect = 0.049
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPC 340
Query: 198 YCALLQA 218
LL +
Sbjct: 341 LLHLLSS 347
Score = 31.9 bits (69), Expect = 1.4
Identities = 19/75 (25%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W I+N+ G Q+ A++ +
Sbjct: 320 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDAN 378
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 379 IFPVLIEILQKAEFR 393
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 120 bits (288), Expect = 4e-27
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ ++S
Sbjct: 361 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSL 420
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQ-----VRGMCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + V C +EE LD+IE
Sbjct: 421 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIE 480
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +E++D+S P D Q QF
Sbjct: 481 FLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQF 522
Score = 41.1 bits (92), Expect = 0.002
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q + I++G + PI L++ D + Q++A WA+ N+ G + D +L+
Sbjct: 150 TNIASGTSQQTKIVIEAGAV-PIFIELLNSDFEDVQEQAVWALGNIA-GDSSVCRDYVLN 207
Query: 180 CDILSPYCALL 212
C IL+P LL
Sbjct: 208 CSILNPLLTLL 218
Score = 36.7 bits (81), Expect = 0.049
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPC 340
Query: 198 YCALLQA 218
LL +
Sbjct: 341 LLHLLSS 347
Score = 31.9 bits (69), Expect = 1.4
Identities = 19/75 (25%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W I+N+ G Q+ A++ +
Sbjct: 320 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDAN 378
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 379 IFPVLIEILQKAEFR 393
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 120 bits (288), Expect = 4e-27
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ ++S
Sbjct: 361 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSL 420
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQ-----VRGMCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + V C +EE LD+IE
Sbjct: 421 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIE 480
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +E++D+S P D Q QF
Sbjct: 481 FLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQF 522
Score = 41.1 bits (92), Expect = 0.002
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q + I++G + PI L++ D + Q++A WA+ N+ G + D +L+
Sbjct: 150 TNIASGTSQQTKIVIEAGAV-PIFIELLNSDFEDVQEQAVWALGNIA-GDSSVCRDYVLN 207
Query: 180 CDILSPYCALL 212
C IL+P LL
Sbjct: 208 CSILNPLLTLL 218
Score = 36.7 bits (81), Expect = 0.049
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPC 340
Query: 198 YCALLQA 218
LL +
Sbjct: 341 LLHLLSS 347
Score = 31.9 bits (69), Expect = 1.4
Identities = 19/75 (25%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W I+N+ G Q+ A++ +
Sbjct: 320 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDAN 378
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 379 IFPVLIEILQKAEFR 393
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 120 bits (288), Expect = 4e-27
Identities = 62/162 (38%), Positives = 95/162 (58%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+ ++S
Sbjct: 361 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSL 420
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQ-----VRGMCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + V C +EE LD+IE
Sbjct: 421 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIE 480
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF +E++D+S P D Q QF
Sbjct: 481 FLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQF 522
Score = 41.1 bits (92), Expect = 0.002
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIK-CQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q + I++G + PI L++ D + Q++A WA+ N+ G + D +L+
Sbjct: 150 TNIASGTSQQTKIVIEAGAV-PIFIELLNSDFEDVQEQAVWALGNIA-GDSSVCRDYVLN 207
Query: 180 CDILSPYCALL 212
C IL+P LL
Sbjct: 208 CSILNPLLTLL 218
Score = 36.7 bits (81), Expect = 0.049
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 282 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPC 340
Query: 198 YCALLQA 218
LL +
Sbjct: 341 LLHLLSS 347
Score = 31.9 bits (69), Expect = 1.4
Identities = 19/75 (25%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W I+N+ G Q+ A++ +
Sbjct: 320 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDAN 378
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 379 IFPVLIEILQKAEFR 393
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.5 bits (73), Expect = 0.46
Identities = 26/115 (22%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H D+ + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDVNIVVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
Score = 33.5 bits (73), Expect = 0.46
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A+ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVGQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 32.3 bits (70), Expect = 1.1
Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 119 bits (287), Expect = 5e-27
Identities = 58/141 (41%), Positives = 88/141 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAAWAI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 114 bits (275), Expect = 2e-25
Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+ ++ I +L D QKEAAWAI+NL + G +Q+ ++
Sbjct: 111 SNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQ 170
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL+++L+ A D+ + +EE G L++IE LQ H
Sbjct: 171 NVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--DEAETIGNLIEECGGLEKIEQLQNH 228
Query: 363 ENEQIYKKSIHILDSYFME---EEDASTQP 443
ENE IYK + I+D +F +ED S P
Sbjct: 229 ENEDIYKLAYEIIDQFFSSDDIDEDPSLVP 258
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/61 (42%), Positives = 38/61 (62%)
Frame = +3
Query: 30 QIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCAL 209
QIQ IDSG++ + +L H ++K Q A A+ N+ + GT EQ +L+CD LS + AL
Sbjct: 36 QIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDALSHFPAL 94
Query: 210 L 212
L
Sbjct: 95 L 95
Score = 37.9 bits (84), Expect = 0.021
Identities = 20/73 (27%), Positives = 34/73 (46%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ++ L +L H K KEA W ++N+ G +Q+ A++ +
Sbjct: 70 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAN 128
Query: 186 ILSPYCALLQARD 224
++ LL D
Sbjct: 129 LVPMIIHLLDKGD 141
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 114 bits (275), Expect = 2e-25
Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+ ++ I +L D QKEAAWAI+NL + G +Q+ ++
Sbjct: 351 SNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL+++L+ A D+ + +EE G L++IE LQ H
Sbjct: 411 NVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--DEAETIGNLIEECGGLEKIEQLQNH 468
Query: 363 ENEQIYKKSIHILDSYFME---EEDASTQP 443
ENE IYK + I+D +F +ED S P
Sbjct: 469 ENEDIYKLAYEIIDQFFSSDDIDEDPSLVP 498
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/61 (42%), Positives = 38/61 (62%)
Frame = +3
Query: 30 QIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCAL 209
QIQ IDSG++ + +L H ++K Q A A+ N+ + GT EQ +L+CD LS + AL
Sbjct: 276 QIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDALSHFPAL 334
Query: 210 L 212
L
Sbjct: 335 L 335
Score = 37.9 bits (84), Expect = 0.021
Identities = 20/73 (27%), Positives = 34/73 (46%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ++ L +L H K KEA W ++N+ G +Q+ A++ +
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAN 368
Query: 186 ILSPYCALLQARD 224
++ LL D
Sbjct: 369 LVPMIIHLLDKGD 381
Score = 36.7 bits (81), Expect = 0.049
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + L D Q EAAWA+TN+ GT EQ A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIA-SGTSEQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL +
Sbjct: 164 RLLHS 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVH--HDIKCQKEAAWAITNLCLGGTPEQLDAML 176
+N+ +GT+ Q Q + S + P+ L+H H C+ +A WA+ N+ +G P+ D ++
Sbjct: 140 TNIASGTSEQTQAVVQSNAV-PLFLRLLHSPHQNVCE-QAVWALGNI-IGDGPQCRDYVI 196
Query: 177 SCDILSPYCALL 212
S ++ P + +
Sbjct: 197 SLGVVKPLLSFI 208
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 114 bits (275), Expect = 2e-25
Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+ ++ I +L D QKEAAWAI+NL + G +Q+ ++
Sbjct: 351 SNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL+++L+ A D+ + +EE G L++IE LQ H
Sbjct: 411 NVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--DEAETIGNLIEECGGLEKIEQLQNH 468
Query: 363 ENEQIYKKSIHILDSYFME---EEDASTQP 443
ENE IYK + I+D +F +ED S P
Sbjct: 469 ENEDIYKLAYEIIDQFFSSDDIDEDPSLVP 498
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/61 (42%), Positives = 38/61 (62%)
Frame = +3
Query: 30 QIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCAL 209
QIQ IDSG++ + +L H ++K Q A A+ N+ + GT EQ +L+CD LS + AL
Sbjct: 276 QIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDALSHFPAL 334
Query: 210 L 212
L
Sbjct: 335 L 335
Score = 37.9 bits (84), Expect = 0.021
Identities = 20/73 (27%), Positives = 34/73 (46%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ++ L +L H K KEA W ++N+ G +Q+ A++ +
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAN 368
Query: 186 ILSPYCALLQARD 224
++ LL D
Sbjct: 369 LVPMIIHLLDKGD 381
Score = 36.7 bits (81), Expect = 0.049
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + L D Q EAAWA+TN+ GT EQ A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIA-SGTSEQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL +
Sbjct: 164 RLLHS 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVH--HDIKCQKEAAWAITNLCLGGTPEQLDAML 176
+N+ +GT+ Q Q + S + P+ L+H H C+ +A WA+ N+ +G P+ D ++
Sbjct: 140 TNIASGTSEQTQAVVQSNAV-PLFLRLLHSPHQNVCE-QAVWALGNI-IGDGPQCRDYVI 196
Query: 177 SCDILSPYCALL 212
S ++ P + +
Sbjct: 197 SLGVVKPLLSFI 208
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 114 bits (275), Expect = 2e-25
Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+ ++ I +L D QKEAAWAI+NL + G +Q+ ++
Sbjct: 351 SNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL+++L+ A D+ + +EE G L++IE LQ H
Sbjct: 411 NVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--DEAETIGNLIEECGGLEKIEQLQNH 468
Query: 363 ENEQIYKKSIHILDSYFME---EEDASTQP 443
ENE IYK + I+D +F +ED S P
Sbjct: 469 ENEDIYKLAYEIIDQFFSSDDIDEDPSLVP 498
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/61 (42%), Positives = 38/61 (62%)
Frame = +3
Query: 30 QIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCAL 209
QIQ IDSG++ + +L H ++K Q A A+ N+ + GT EQ +L+CD LS + AL
Sbjct: 276 QIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDALSHFPAL 334
Query: 210 L 212
L
Sbjct: 335 L 335
Score = 37.9 bits (84), Expect = 0.021
Identities = 20/73 (27%), Positives = 34/73 (46%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ++ L +L H K KEA W ++N+ G +Q+ A++ +
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAN 368
Query: 186 ILSPYCALLQARD 224
++ LL D
Sbjct: 369 LVPMIIHLLDKGD 381
Score = 36.7 bits (81), Expect = 0.049
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + L D Q EAAWA+TN+ GT EQ A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIA-SGTSEQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL +
Sbjct: 164 RLLHS 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVH--HDIKCQKEAAWAITNLCLGGTPEQLDAML 176
+N+ +GT+ Q Q + S + P+ L+H H C+ +A WA+ N+ +G P+ D ++
Sbjct: 140 TNIASGTSEQTQAVVQSNAV-PLFLRLLHSPHQNVCE-QAVWALGNI-IGDGPQCRDYVI 196
Query: 177 SCDILSPYCALL 212
S ++ P + +
Sbjct: 197 SLGVVKPLLSFI 208
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 114 bits (275), Expect = 2e-25
Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+ ++ I +L D QKEAAWAI+NL + G +Q+ ++
Sbjct: 351 SNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL+++L+ A D+ + +EE G L++IE LQ H
Sbjct: 411 NVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAE--DEAETIGNLIEECGGLEKIEQLQNH 468
Query: 363 ENEQIYKKSIHILDSYFME---EEDASTQP 443
ENE IYK + I+D +F +ED S P
Sbjct: 469 ENEDIYKLAYEIIDQFFSSDDIDEDPSLVP 498
Score = 50.4 bits (115), Expect = 4e-06
Identities = 26/61 (42%), Positives = 38/61 (62%)
Frame = +3
Query: 30 QIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCAL 209
QIQ IDSG++ + +L H ++K Q A A+ N+ + GT EQ +L+CD LS + AL
Sbjct: 276 QIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDALSHFPAL 334
Query: 210 L 212
L
Sbjct: 335 L 335
Score = 37.9 bits (84), Expect = 0.021
Identities = 20/73 (27%), Positives = 34/73 (46%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ GT Q Q ++ L +L H K KEA W ++N+ G +Q+ A++ +
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI-TAGNQQQVQAVIDAN 368
Query: 186 ILSPYCALLQARD 224
++ LL D
Sbjct: 369 LVPMIIHLLDKGD 381
Score = 36.7 bits (81), Expect = 0.049
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + L D Q EAAWA+TN+ GT EQ A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIA-SGTSEQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL +
Sbjct: 164 RLLHS 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVH--HDIKCQKEAAWAITNLCLGGTPEQLDAML 176
+N+ +GT+ Q Q + S + P+ L+H H C+ +A WA+ N+ +G P+ D ++
Sbjct: 140 TNIASGTSEQTQAVVQSNAV-PLFLRLLHSPHQNVCE-QAVWALGNI-IGDGPQCRDYVI 196
Query: 177 SCDILSPYCALL 212
S ++ P + +
Sbjct: 197 SLGVVKPLLSFI 208
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 113 bits (273), Expect = 3e-25
Identities = 57/141 (40%), Positives = 87/141 (61%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG Q+Q ID+G++ I L D QKEAA AI+NL + G +Q++ ++
Sbjct: 351 SNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAARAISNLTISGRKDQVEYLVQQ 410
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQH 362
+++ P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQH
Sbjct: 411 NVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQH 468
Query: 363 ENEQIYKKSIHILDSYFMEEE 425
ENE IYK + I+D YF ++
Sbjct: 469 ENEDIYKLAFEIIDQYFSGDD 489
Score = 49.6 bits (113), Expect = 7e-06
Identities = 27/65 (41%), Positives = 39/65 (60%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G QIQ IDSGV+ + +L H ++K Q A A+ N+ + GT EQ +L+CD+LS
Sbjct: 272 GGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNI-VTGTDEQTQVVLNCDVLSH 330
Query: 198 YCALL 212
+ LL
Sbjct: 331 FPNLL 335
Score = 35.5 bits (78), Expect = 0.11
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +3
Query: 27 PQIQRAIDSGVLEPIARVLVHHDI-KCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYC 203
P I I SG+L + + L D Q EAAWA+TN+ GT Q A++ + + +
Sbjct: 105 PPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIA-SGTSAQTQAVVQSNAVPLFL 163
Query: 204 ALLQA 218
LL++
Sbjct: 164 RLLRS 168
Score = 35.1 bits (77), Expect = 0.15
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVL-VHHDIKCQKEAAWAITNLCLGGTPEQLDAMLS 179
+N+ +GT+ Q Q + S + R+L H C+ +A WA+ N+ +G P+ D ++S
Sbjct: 140 TNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCE-QAVWALGNI-IGDGPQCRDYVIS 197
Query: 180 CDILSPYCALL 212
++ P + +
Sbjct: 198 LGVVKPLLSFI 208
Score = 33.9 bits (74), Expect = 0.35
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +3
Query: 66 PIARVLVHH-DIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPYCALLQARDHRAIIV 242
P VL++H DI + WA++ L GG EQ+ ++ ++ LL ++ +
Sbjct: 245 PALCVLIYHTDINILVDTVWALSYLTDGGN-EQIQMVIDSGVVPFLVPLLSHQEVKVQTA 303
Query: 243 VLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQIYKKSIHILDS 407
L + +++ + QV C L NL H E+I K+++ L +
Sbjct: 304 ALRAVGNIVTGTDEQTQVVLNC------DVLSHFPNLLSHPKEKINKEAVWFLSN 352
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 113 bits (271), Expect = 5e-25
Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GG+ EQ+ ++
Sbjct: 363 SNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVEL 422
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRG-----MCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G C +EE LD+IE
Sbjct: 423 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIE 482
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF E+ED+S P D Q Q+
Sbjct: 483 FLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQY 524
Score = 36.3 bits (80), Expect = 0.065
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ ID+GV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQS 342
Query: 198 YCALLQA 218
LL +
Sbjct: 343 LLHLLSS 349
Score = 33.9 bits (74), Expect = 0.35
Identities = 18/75 (24%), Positives = 34/75 (45%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L+ + +L +KEA W I+N+ G Q+ ++ +
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNI-TAGNRAQIQTVIDAN 380
Query: 186 ILSPYCALLQARDHR 230
I ++LQ + R
Sbjct: 381 IFPALISILQTAEFR 395
Score = 29.1 bits (62), Expect = 9.9
Identities = 11/38 (28%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +3
Query: 45 IDSGVLEPIARVLVHHD-IKCQKEAAWAITNLCLGGTP 155
+D +L P+ ++ + + + A WA++NLC G +P
Sbjct: 208 LDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 113 bits (271), Expect = 5e-25
Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GG+ EQ+ ++
Sbjct: 363 SNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVEL 422
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRG-----MCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G C +EE LD+IE
Sbjct: 423 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIE 482
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF E+ED+S P D Q Q+
Sbjct: 483 FLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQY 524
Score = 36.3 bits (80), Expect = 0.065
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ ID+GV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQS 342
Query: 198 YCALLQA 218
LL +
Sbjct: 343 LLHLLSS 349
Score = 33.9 bits (74), Expect = 0.35
Identities = 18/75 (24%), Positives = 34/75 (45%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L+ + +L +KEA W I+N+ G Q+ ++ +
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNI-TAGNRAQIQTVIDAN 380
Query: 186 ILSPYCALLQARDHR 230
I ++LQ + R
Sbjct: 381 IFPALISILQTAEFR 395
Score = 29.1 bits (62), Expect = 9.9
Identities = 11/38 (28%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +3
Query: 45 IDSGVLEPIARVLVHHD-IKCQKEAAWAITNLCLGGTP 155
+D +L P+ ++ + + + A WA++NLC G +P
Sbjct: 208 LDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 113 bits (271), Expect = 5e-25
Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GG+ EQ+ ++
Sbjct: 363 SNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVEL 422
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRG-----MCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G C +EE LD+IE
Sbjct: 423 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIE 482
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF E+ED+S P D Q Q+
Sbjct: 483 FLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQY 524
Score = 36.3 bits (80), Expect = 0.065
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ ID+GV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQS 342
Query: 198 YCALLQA 218
LL +
Sbjct: 343 LLHLLSS 349
Score = 33.9 bits (74), Expect = 0.35
Identities = 18/75 (24%), Positives = 34/75 (45%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L+ + +L +KEA W I+N+ G Q+ ++ +
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNI-TAGNRAQIQTVIDAN 380
Query: 186 ILSPYCALLQARDHR 230
I ++LQ + R
Sbjct: 381 IFPALISILQTAEFR 395
Score = 29.1 bits (62), Expect = 9.9
Identities = 11/38 (28%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +3
Query: 45 IDSGVLEPIARVLVHHD-IKCQKEAAWAITNLCLGGTP 155
+D +L P+ ++ + + + A WA++NLC G +P
Sbjct: 208 LDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 113 bits (271), Expect = 5e-25
Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GG+ EQ+ ++
Sbjct: 363 SNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVEL 422
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRG-----MCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G C +EE LD+IE
Sbjct: 423 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIE 482
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF E+ED+S P D Q Q+
Sbjct: 483 FLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQY 524
Score = 36.3 bits (80), Expect = 0.065
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ ID+GV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQS 342
Query: 198 YCALLQA 218
LL +
Sbjct: 343 LLHLLSS 349
Score = 33.9 bits (74), Expect = 0.35
Identities = 18/75 (24%), Positives = 34/75 (45%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L+ + +L +KEA W I+N+ G Q+ ++ +
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNI-TAGNRAQIQTVIDAN 380
Query: 186 ILSPYCALLQARDHR 230
I ++LQ + R
Sbjct: 381 IFPALISILQTAEFR 395
Score = 29.1 bits (62), Expect = 9.9
Identities = 11/38 (28%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +3
Query: 45 IDSGVLEPIARVLVHHD-IKCQKEAAWAITNLCLGGTP 155
+D +L P+ ++ + + + A WA++NLC G +P
Sbjct: 208 LDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 113 bits (271), Expect = 5e-25
Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GG+ EQ+ ++
Sbjct: 363 SNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVEL 422
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRG-----MCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G C +EE LD+IE
Sbjct: 423 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIE 482
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF E+ED+S P D Q Q+
Sbjct: 483 FLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQY 524
Score = 36.3 bits (80), Expect = 0.065
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ ID+GV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQS 342
Query: 198 YCALLQA 218
LL +
Sbjct: 343 LLHLLSS 349
Score = 33.9 bits (74), Expect = 0.35
Identities = 18/75 (24%), Positives = 34/75 (45%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L+ + +L +KEA W I+N+ G Q+ ++ +
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNI-TAGNRAQIQTVIDAN 380
Query: 186 ILSPYCALLQARDHR 230
I ++LQ + R
Sbjct: 381 IFPALISILQTAEFR 395
Score = 29.1 bits (62), Expect = 9.9
Identities = 11/38 (28%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +3
Query: 45 IDSGVLEPIARVLVHHD-IKCQKEAAWAITNLCLGGTP 155
+D +L P+ ++ + + + A WA++NLC G +P
Sbjct: 208 LDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 113 bits (271), Expect = 5e-25
Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 6/162 (3%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSC 182
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GG+ EQ+ ++
Sbjct: 363 SNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVEL 422
Query: 183 DILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRG-----MCIKLEEIGALDQIE 347
+ P C LL D + + V L+GL ++L+ + + G C +EE LD+IE
Sbjct: 423 GCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIE 482
Query: 348 NLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
LQ HEN++IY+K+ +++ YF E+ED+S P D Q Q+
Sbjct: 483 FLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQY 524
Score = 36.3 bits (80), Expect = 0.065
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ ID+GV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 284 GPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQS 342
Query: 198 YCALLQA 218
LL +
Sbjct: 343 LLHLLSS 349
Score = 33.9 bits (74), Expect = 0.35
Identities = 18/75 (24%), Positives = 34/75 (45%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L+ + +L +KEA W I+N+ G Q+ ++ +
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNI-TAGNRAQIQTVIDAN 380
Query: 186 ILSPYCALLQARDHR 230
I ++LQ + R
Sbjct: 381 IFPALISILQTAEFR 395
Score = 29.1 bits (62), Expect = 9.9
Identities = 11/38 (28%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +3
Query: 45 IDSGVLEPIARVLVHHD-IKCQKEAAWAITNLCLGGTP 155
+D +L P+ ++ + + + A WA++NLC G +P
Sbjct: 208 LDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSP 245
>AL132795-7|CAI20502.1| 121|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 121
Score = 71.7 bits (168), Expect = 1e-12
Identities = 37/106 (34%), Positives = 61/106 (57%), Gaps = 6/106 (5%)
Frame = +3
Query: 171 MLSCDILSPYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGM-----CIKLEEIGAL 335
+++ + P C LL D + + V L+GL ++L+ + + G+ C +EE L
Sbjct: 2 LVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGL 61
Query: 336 DQIENLQQHENEQIYKKSIHILDSYF-MEEEDASTQPAHDHEQYQF 470
D+IE LQ HEN++IY+K+ +++ YF +EE+D S P D Q QF
Sbjct: 62 DKIEFLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDENQQQF 107
>AL135901-9|CAI40722.1| 90|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 90
Score = 69.7 bits (163), Expect = 6e-12
Identities = 34/77 (44%), Positives = 49/77 (63%)
Frame = +3
Query: 195 PYCALLQARDHRAIIVVLDGLTHLLQAAAKYDQVRGMCIKLEEIGALDQIENLQQHENEQ 374
P+C LL +D + + VVLDGL ++L A D+ + +EE G L++IE LQQHENE
Sbjct: 1 PFCNLLSVKDSQVVQVVLDGLKNILIMAG--DEASTIAEIIEECGGLEKIEVLQQHENED 58
Query: 375 IYKKSIHILDSYFMEEE 425
IYK + I+D YF ++
Sbjct: 59 IYKLAFEIIDQYFSGDD 75
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 56.4 bits (130), Expect = 6e-08
Identities = 25/54 (46%), Positives = 34/54 (62%)
Frame = +3
Query: 3 SNVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQL 164
SN+ AG QIQ ID+ + + +L + + +KEAAWAITN GGTPEQ+
Sbjct: 268 SNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 321
Score = 36.7 bits (81), Expect = 0.049
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +3
Query: 18 GTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSP 197
G +IQ IDSGV + +L+H+D K A A+ N+ + G Q +L+C L
Sbjct: 189 GPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPC 247
Query: 198 YCALLQA 218
LL +
Sbjct: 248 LLHLLSS 254
Score = 31.9 bits (69), Expect = 1.4
Identities = 19/75 (25%), Positives = 33/75 (44%)
Frame = +3
Query: 6 NVFAGTAPQIQRAIDSGVLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCD 185
N+ G Q Q ++ L + +L +KEA W I+N+ G Q+ A++ +
Sbjct: 227 NIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI-TAGNRAQIQAVIDAN 285
Query: 186 ILSPYCALLQARDHR 230
I +LQ + R
Sbjct: 286 IFPVLIEILQKAEFR 300
Score = 30.3 bits (65), Expect = 4.3
Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = +3
Query: 24 APQIQRAIDSG-VLEPIARVLVHHDIKCQKEAAWAITNLCLGGTPEQLDAMLSCDILSPY 200
+P I I++ V++ L ++ C +A WA+ N+ G + D +L+C IL+P
Sbjct: 64 SPPIDEVINTPRVVDRFVEFLKRNE-NCTLQAVWALGNIA-GDSSVCRDYVLNCSILNPL 121
Query: 201 CALL 212
LL
Sbjct: 122 LTLL 125
>AF036977-1|AAD02090.1| 331|Homo sapiens unknown protein.
Length = 331
Score = 33.9 bits (74), Expect = 0.35
Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Frame = +1
Query: 118 PGPLQT-CVLEAPLNNWTPCCPVIFCRR 198
P PL + C+ E+P NWTPC ++ C R
Sbjct: 301 PVPLSSLCITESPSQNWTPCLLLLTCPR 328
>BC068549-1|AAH68549.1| 862|Homo sapiens LOC100101438 protein
protein.
Length = 862
Score = 32.7 bits (71), Expect = 0.80
Identities = 11/52 (21%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + H+++S F E ++ PAH + ++F+T
Sbjct: 37 QLGITHTVGSLSTKPESDVLMQDFHMVESIFFPSEGSNLTPAHHYNAFRFKT 88
>AL365510-1|CAM19360.1| 862|Homo sapiens Novel protein similar to
phosphatidylinositol-4-phosphate 5-kinase, type I, alp
protein.
Length = 862
Score = 32.7 bits (71), Expect = 0.80
Identities = 11/52 (21%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + H+++S F E ++ PAH + ++F+T
Sbjct: 37 QLGITHTVGSLSTKPESDVLMQDFHMVESIFFPSEGSNLTPAHHYNAFRFKT 88
>X92493-1|CAA63224.1| 540|Homo sapiens STM-7 protein.
Length = 540
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>U52387-1|AAC51327.1| 540|Homo sapiens STM7 protein.
Length = 540
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>BC030587-1|AAH30587.1| 549|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 549
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 74 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 125
>AL356219-4|CAI14095.1| 540|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 540
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL356219-3|CAI14094.1| 162|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 162
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL356219-2|CAI14093.1| 157|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 157
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL356219-1|CAI14092.1| 103|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 103
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL354794-6|CAI12625.1| 540|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 540
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL354794-5|CAI12624.1| 162|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 162
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL354794-4|CAI12623.1| 157|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 157
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL354794-3|CAI12622.1| 103|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 103
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>AL162730-3|CAH71831.1| 540|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
protein.
Length = 540
Score = 31.9 bits (69), Expect = 1.4
Identities = 11/52 (21%), Positives = 27/52 (51%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + NL + + ++++S F+ E ++ PAH + ++F+T
Sbjct: 34 QLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKT 85
>U78577-1|AAC50912.1| 500|Homo sapiens 68 kDa type I
phosphatidylinositol-4-phosphate 5-kinase alpha protein.
Length = 500
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 77 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 128
>U78576-1|AAC50911.1| 562|Homo sapiens 68 kDa type I
phosphatidylinositol-4-phosphate 5-kinase alpha protein.
Length = 562
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 90 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 141
>U78575-1|AAC50910.1| 549|Homo sapiens 68 kDa type I
phosphatidylinositol-4-phosphate 5-kinase alpha protein.
Length = 549
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 77 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 128
>BC007833-1|AAH07833.1| 500|Homo sapiens PIP5K1A protein protein.
Length = 500
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 77 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 128
>AL592424-18|CAI16386.1| 562|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
protein.
Length = 562
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 90 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 141
>AL592424-17|CAI16387.1| 549|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
protein.
Length = 549
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 77 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 128
>AL592424-16|CAI16388.1| 500|Homo sapiens
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
protein.
Length = 500
Score = 31.5 bits (68), Expect = 1.9
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 77 QLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKT 128
>BC028580-1|AAH28580.1| 512|Homo sapiens MGC26597 protein protein.
Length = 512
Score = 30.3 bits (65), Expect = 4.3
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 77 QLGITYTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNAFRFKT 128
>AY557347-1|AAS67921.1| 174|Homo sapiens unknown protein.
Length = 174
Score = 29.9 bits (64), Expect = 5.7
Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Frame = +1
Query: 91 MTSSARRKRPGPLQTCVLE----APLNNWTPCCPVIFCRR 198
+T+ RKR P + CVLE P CC ++FC++
Sbjct: 105 LTAPTDRKRSLPEEPCVLEIRRRPPRRGGCACCELLFCKK 144
>AY255147-6|AAO66805.1| 226|Homo sapiens ATP synthase F0 subunit 6
protein.
Length = 226
Score = 29.9 bits (64), Expect = 5.7
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 5/69 (7%)
Frame = -1
Query: 500 LEVYGCIICPELILLVVVSGLRAGVLLLHKVGVQDVDALLVN----LFIFMLL*VLNLVQ 333
+E +I P + + + + + AG LL+H +G + L +N L IF +L +L +++
Sbjct: 144 IETISLLIQPMALAVRLTANITAGHLLMHLIGSATLAMLTINLPSTLIIFTILILLTILE 203
Query: 332 SA-NLFQLY 309
A L Q Y
Sbjct: 204 IAVALIQAY 212
>AY017307-1|AAG52948.1| 3389|Homo sapiens CUB and sushi multiple
domains protein 1 short form protein.
Length = 3389
Score = 29.9 bits (64), Expect = 5.7
Identities = 15/51 (29%), Positives = 21/51 (41%)
Frame = +1
Query: 115 RPGPLQTCVLEAPLNNWTPCCPVIFCRRTAPCSRPGITEPSS*CWMDSLIY 267
R P +TC+L + P C + C + P G E S W S+ Y
Sbjct: 2897 RGSPERTCLLNGSWSGLQPVCEAVLCPQPPPVQN-GTVEGSDFRWGSSISY 2946
>AK093877-1|BAC04239.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ36558 fis, clone TRACH2009107, highly similar to
ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING (EC
1.2.1.5). ).
Length = 570
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Frame = +1
Query: 70 SLGSWCIMTSSARRKRPGPLQTCVLEAP-LNNWTPC 174
S SWC+ +S A+ PG + L P L W+ C
Sbjct: 99 SRASWCLRSSQAQVSTPGDTERACLPPPLLGGWSFC 134
>AC004637-1|AAC15471.1| 156|Homo sapiens KIAA0589 protein.
Length = 156
Score = 29.5 bits (63), Expect = 7.5
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 84 QLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKT 135
>AB011161-1|BAA25515.1| 687|Homo sapiens KIAA0589 protein protein.
Length = 687
Score = 29.5 bits (63), Expect = 7.5
Identities = 10/52 (19%), Positives = 26/52 (50%)
Frame = +3
Query: 321 EIGALDQIENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQFRT 476
++G + +L + + ++++S F E ++ PAH + ++F+T
Sbjct: 103 QLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKT 154
>BC051868-1|AAH51868.2| 741|Homo sapiens UBE2O protein protein.
Length = 741
Score = 29.1 bits (62), Expect = 9.9
Identities = 12/25 (48%), Positives = 14/25 (56%)
Frame = +3
Query: 417 EEEDASTQPAHDHEQYQFRTNDAAI 491
EEED S DH ++FRT D I
Sbjct: 85 EEEDVSVYDIADHPDFRFRTTDIVI 109
>BC036820-1|AAH36820.1| 1025|Homo sapiens UBE2O protein protein.
Length = 1025
Score = 29.1 bits (62), Expect = 9.9
Identities = 12/25 (48%), Positives = 14/25 (56%)
Frame = +3
Query: 417 EEEDASTQPAHDHEQYQFRTNDAAI 491
EEED S DH ++FRT D I
Sbjct: 369 EEEDVSVYDIADHPDFRFRTTDIVI 393
>AK025999-1|BAB15313.1| 742|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22346 fis, clone HRC06158. ).
Length = 742
Score = 29.1 bits (62), Expect = 9.9
Identities = 12/25 (48%), Positives = 14/25 (56%)
Frame = +3
Query: 417 EEEDASTQPAHDHEQYQFRTNDAAI 491
EEED S DH ++FRT D I
Sbjct: 85 EEEDVSVYDIADHPDFRFRTTDIVI 109
>AF271379-1|AAG49889.1| 1241|Homo sapiens interphotoreceptor matrix
proteoglycan 200 protein.
Length = 1241
Score = 29.1 bits (62), Expect = 9.9
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = +3
Query: 342 IENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQF 470
IE + EQI + SIH+L + EE S+ H H + +F
Sbjct: 231 IEEATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEF 273
>AF173155-1|AAF06999.1| 1241|Homo sapiens interphotoreceptor matrix
proteoglycan 200 protein.
Length = 1241
Score = 29.1 bits (62), Expect = 9.9
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = +3
Query: 342 IENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQF 470
IE + EQI + SIH+L + EE S+ H H + +F
Sbjct: 231 IEEATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEF 273
>AF157624-1|AAF13154.1| 1241|Homo sapiens Spacrcan protein.
Length = 1241
Score = 29.1 bits (62), Expect = 9.9
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = +3
Query: 342 IENLQQHENEQIYKKSIHILDSYFMEEEDASTQPAHDHEQYQF 470
IE + EQI + SIH+L + EE S+ H H + +F
Sbjct: 231 IEEATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEF 273
>AB051521-1|BAB21825.1| 1313|Homo sapiens KIAA1734 protein protein.
Length = 1313
Score = 29.1 bits (62), Expect = 9.9
Identities = 12/25 (48%), Positives = 14/25 (56%)
Frame = +3
Query: 417 EEEDASTQPAHDHEQYQFRTNDAAI 491
EEED S DH ++FRT D I
Sbjct: 657 EEEDVSVYDIADHPDFRFRTTDIVI 681
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,920,500
Number of Sequences: 237096
Number of extensions: 1965090
Number of successful extensions: 13359
Number of sequences better than 10.0: 75
Number of HSP's better than 10.0 without gapping: 12706
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13293
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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