Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS318G05f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 84 3e-16
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 84 3e-16
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 84 3e-16
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 84 3e-16
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 82 1e-15
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 82 1e-15
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 82 1e-15
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 82 1e-15
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 82 1e-15
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 82 1e-15
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 82 1e-15
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 75 1e-13
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 75 1e-13
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 70 6e-12
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 70 6e-12
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 70 6e-12
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 70 6e-12
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 70 6e-12
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 70 6e-12
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 70 6e-12
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 70 6e-12
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 70 6e-12
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 70 6e-12
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 66 7e-11
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 66 7e-11
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 64 2e-10
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 62 9e-10
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 62 9e-10
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 62 9e-10
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 62 9e-10
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 62 9e-10
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 62 9e-10
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 62 9e-10
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 62 9e-10
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 62 9e-10
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 62 9e-10
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 62 9e-10
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 62 9e-10
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 62 9e-10
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 59 8e-09
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.012
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 33 0.46
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 33 0.46
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 33 0.46
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 33 0.46
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 33 0.46
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 33 0.46
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 33 0.46
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 33 0.46
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 33 0.46
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 33 0.46
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 33 0.46
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 33 0.46
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 33 0.46
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 33 0.46
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 33 0.46
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 33 0.46
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 33 0.46
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 33 0.46
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 33 0.46
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 33 0.46
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 33 0.46
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 33 0.46
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 33 0.46
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 33 0.46
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 33 0.46
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 33 0.46
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 33 0.46
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 33 0.46
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 1.1
AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens ... 32 1.4
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 3.2
BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated prot... 30 4.3
BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated prot... 30 4.3
AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated prot... 30 4.3
AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens ... 24 5.7
BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein. 24 7.1
BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein. 24 7.1
AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosph... 24 7.1
BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19 ... 29 7.5
AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein pr... 29 7.5
AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens ... 29 7.5
AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens ... 29 7.5
AJ628245-1|CAF31637.1| 177|Homo sapiens keratin associated prot... 29 7.5
AB126080-1|BAD20207.1| 156|Homo sapiens keratin associated prot... 29 7.5
AB126071-1|BAD20198.1| 177|Homo sapiens keratin associated prot... 29 7.5
AJ628247-1|CAF31639.1| 221|Homo sapiens keratin associated prot... 29 9.9
AB126074-1|BAD20201.1| 221|Homo sapiens keratin associated prot... 29 9.9
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 83.8 bits (198), Expect = 3e-16
Identities = 31/59 (52%), Positives = 47/59 (79%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG
Sbjct: 101 NLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGG 159
Score = 63.3 bits (147), Expect = 5e-10
Identities = 36/82 (43%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Frame = +3
Query: 111 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 275
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 276 YGVISIGTPPQSFKVVFDTGSS 341
+G I +GTPPQ+F V FDTGSS
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSS 100
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 83.8 bits (198), Expect = 3e-16
Identities = 31/59 (52%), Positives = 47/59 (79%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG
Sbjct: 101 NLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGG 159
Score = 62.9 bits (146), Expect = 7e-10
Identities = 36/82 (43%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Frame = +3
Query: 111 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 275
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 276 YGVISIGTPPQSFKVVFDTGSS 341
+G I +GTPPQ+F V FDTGSS
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSS 100
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 83.8 bits (198), Expect = 3e-16
Identities = 31/59 (52%), Positives = 47/59 (79%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG
Sbjct: 101 NLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGG 159
Score = 62.9 bits (146), Expect = 7e-10
Identities = 36/82 (43%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Frame = +3
Query: 111 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 275
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 276 YGVISIGTPPQSFKVVFDTGSS 341
+G I +GTPPQ+F V FDTGSS
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSS 100
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 83.8 bits (198), Expect = 3e-16
Identities = 31/59 (52%), Positives = 47/59 (79%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG
Sbjct: 101 NLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGG 159
Score = 62.9 bits (146), Expect = 7e-10
Identities = 36/82 (43%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Frame = +3
Query: 111 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 275
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 276 YGVISIGTPPQSFKVVFDTGSS 341
+G I +GTPPQ+F V FDTGSS
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSS 100
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 82.2 bits (194), Expect = 1e-15
Identities = 37/57 (64%), Positives = 43/57 (75%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C +IAC +H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V
Sbjct: 102 NLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 81.8 bits (193), Expect = 1e-15
Identities = 46/91 (50%), Positives = 54/91 (59%), Gaps = 11/91 (12%)
Frame = +3
Query: 102 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 248
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L NY+DAQYYG I IGTPPQ F VVFDTGSS
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSS 101
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 75.4 bits (177), Expect = 1e-13
Identities = 27/59 (45%), Positives = 44/59 (74%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G + G LS D +T+GG
Sbjct: 97 NLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGG 155
Score = 60.9 bits (141), Expect = 3e-09
Identities = 34/75 (45%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Frame = +3
Query: 132 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 296
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 297 TPPQSFKVVFDTGSS 341
TPPQ+F V FDTGSS
Sbjct: 82 TPPQNFTVAFDTGSS 96
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 75.4 bits (177), Expect = 1e-13
Identities = 27/59 (45%), Positives = 44/59 (74%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G + G LS D +T+GG
Sbjct: 101 NLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGG 159
Score = 60.9 bits (141), Expect = 3e-09
Identities = 34/75 (45%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Frame = +3
Query: 132 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 296
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 297 TPPQSFKVVFDTGSS 341
TPPQ+F V FDTGSS
Sbjct: 86 TPPQNFTVAFDTGSS 100
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 2 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 69.7 bits (163), Expect = 6e-12
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
N+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 167
Score = 59.7 bits (138), Expect = 6e-09
Identities = 25/31 (80%), Positives = 28/31 (90%)
Frame = +3
Query: 249 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
L+NY+D QYYG I IGTPPQ+FKVVFDTGSS
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSS 108
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 66.1 bits (154), Expect = 7e-11
Identities = 41/95 (43%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 242
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 243 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
+PL NYLD +Y+G I IGTP Q F VVFDTGSS
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSS 98
Score = 58.0 bits (134), Expect = 2e-08
Identities = 26/59 (44%), Positives = 37/59 (62%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C +++AC HN+++ S TY + +I YG+GS++G L D V VGG
Sbjct: 99 NLWVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGG 155
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 66.1 bits (154), Expect = 7e-11
Identities = 41/95 (43%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 242
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 243 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
+PL NYLD +Y+G I IGTP Q F VVFDTGSS
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSS 98
Score = 58.0 bits (134), Expect = 2e-08
Identities = 26/59 (44%), Positives = 37/59 (62%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C +++AC HN+++ S TY + +I YG+GS++G L D V VGG
Sbjct: 99 NLWVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGG 155
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 64.5 bits (150), Expect = 2e-10
Identities = 40/95 (42%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 242
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 243 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
+PL NYLD +Y+G I IGTP Q F V+FDTGSS
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSS 98
Score = 58.0 bits (134), Expect = 2e-08
Identities = 26/59 (44%), Positives = 37/59 (62%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C +++AC HN+++ S TY + +I YG+GS++G L D V VGG
Sbjct: 99 NLWVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGG 155
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 62.5 bits (145), Expect = 9e-10
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV
Sbjct: 96 NLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 76 EISIGTPPQNFLVLFDTGSS 95
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 62.5 bits (145), Expect = 9e-10
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV
Sbjct: 96 NLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 76 EISIGTPPQNFLVLFDTGSS 95
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 62.5 bits (145), Expect = 9e-10
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV
Sbjct: 93 NLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTV 147
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 73 EISIGTPPQNFLVLFDTGSS 92
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 62.5 bits (145), Expect = 9e-10
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV
Sbjct: 96 NLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 76 EISIGTPPQNFLVLFDTGSS 95
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 62.5 bits (145), Expect = 9e-10
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV
Sbjct: 96 NLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 76 EISIGTPPQNFLVLFDTGSS 95
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 62.5 bits (145), Expect = 9e-10
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
NLWVPS C + AC H++++ +S TY NG F++QYGSGSL+GF D +TV
Sbjct: 96 NLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTV 150
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 76 EISIGTPPQNFLVLFDTGSS 95
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 62.5 bits (145), Expect = 9e-10
Identities = 29/59 (49%), Positives = 38/59 (64%)
Frame = +1
Query: 343 NLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
NLWVPS C T+ AC H+++ +S TY G F+IQYG+GSLSG + D V+V G
Sbjct: 101 NLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEG 157
Score = 59.7 bits (138), Expect = 6e-09
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 10/93 (10%)
Frame = +3
Query: 93 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 242
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 243 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSS 341
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSS
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSS 100
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 59.3 bits (137), Expect = 8e-09
Identities = 37/80 (46%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Frame = +3
Query: 129 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 281
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 282 VISIGTPPQSFKVVFDTGSS 341
ISIGTPPQ+F V+FDTGSS
Sbjct: 76 EISIGTPPQNFLVLFDTGSS 95
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.012
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +3
Query: 120 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 272
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 273 YYGVISIGTP 302
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 27 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 62
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 35 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 70
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/17 (64%), Positives = 14/17 (82%)
Frame = +3
Query: 291 IGTPPQSFKVVFDTGSS 341
IGTPPQ +++ DTGSS
Sbjct: 3 IGTPPQKLQILVDTGSS 19
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 51 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 86
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSS 35
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 99
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 33.5 bits (73), Expect = 0.46
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +1
Query: 406 YDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV 513
+D+ +S TY + G ++Y GS +GF+ D VT+
Sbjct: 130 FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTI 165
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSS 341
YY + IGTPPQ +++ DTGSS
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSS 114
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 112
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 33.5 bits (73), Expect = 0.46
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Frame = +3
Query: 273 YYGVISIGTPPQSFKVVFDTGSSK-PLGAFQKVPLHQH 383
YY +++G+PPQ+ ++ DTGSS +GA LH++
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRY 143
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 1.1
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -2
Query: 496 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 398
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens
cDNA FLJ30579 fis, clone BRAWH2006989, weakly similar to
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (EC
2.7.7.6). ).
Length = 260
Score = 31.9 bits (69), Expect = 1.4
Identities = 17/35 (48%), Positives = 18/35 (51%)
Frame = -2
Query: 505 HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTC 401
H+ W GS R C S T S G HS SWT R C
Sbjct: 26 HNSWTGSNRACSSWTGSTRG-HS---SWTGSSRAC 56
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 3.2
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 338 GSGVEYHLERLRRRADTDHSVVLSIK 261
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 4.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 371
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 4.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 371
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated protein
protein.
Length = 129
Score = 30.3 bits (65), Expect = 4.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 371
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens
cDNA FLJ90534 fis, clone OVARC1000003, highly similar to
Homo sapiens sodium dependent phosphate transporter
isoform ).
Length = 397
Score = 24.2 bits (50), Expect(2) = 5.7
Identities = 13/41 (31%), Positives = 16/41 (39%)
Frame = -2
Query: 514 PR*HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAA 392
P+ W S + + TGC R C CR CC A
Sbjct: 297 PKKLQNWMRSLKPWDAVVSKFTGCFQMRCC--CCCRVCCRA 335
Score = 24.2 bits (50), Expect(2) = 5.7
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -2
Query: 418 CGCRTCCAANKRC 380
CGC CC +K C
Sbjct: 340 CGCPKCCRCSKCC 352
>BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 7.1
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -2
Query: 418 CGCRTCCAANKRC 380
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 7.1
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -2
Query: 451 TGCHSRRTSWTCGCRTCCAA 392
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 7.1
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -2
Query: 418 CGCRTCCAANKRC 380
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 7.1
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -2
Query: 451 TGCHSRRTSWTCGCRTCCAA 392
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosphate
transporter isoform NaPi-IIb protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 7.1
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -2
Query: 418 CGCRTCCAANKRC 380
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 7.1
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -2
Query: 451 TGCHSRRTSWTCGCRTCCAA 392
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19
protein.
Length = 458
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 270 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 154
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 137 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 175
>AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein
protein.
Length = 339
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 270 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 154
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 18 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 56
>AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ32768 fis, clone TESTI2001879, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 270 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 154
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ31005 fis, clone HLUNG2000068, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 7.5
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -3
Query: 270 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 154
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AJ628245-1|CAF31637.1| 177|Homo sapiens keratin associated protein
5-8 protein.
Length = 177
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/34 (38%), Positives = 19/34 (55%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAAN 389
GS+ GC S S+ GC S S + C+ CC ++
Sbjct: 93 GSKGGCGSCGGSKGGCGSCGCSQSSCCKPCCCSS 126
>AB126080-1|BAD20207.1| 156|Homo sapiens keratin associated protein
protein.
Length = 156
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAAN 389
GS+ GC S S+ GC S S + C+ CC+++
Sbjct: 62 GSKGGCGSCGSSKGGCGSCGCSQSNCCKPCCSSS 95
>AB126071-1|BAD20198.1| 177|Homo sapiens keratin associated protein
protein.
Length = 177
Score = 29.5 bits (63), Expect = 7.5
Identities = 13/34 (38%), Positives = 19/34 (55%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAAN 389
GS+ GC S S+ GC S S + C+ CC ++
Sbjct: 93 GSKGGCGSCGGSKGGCGSCGCSQSSCCKPCCCSS 126
>AJ628247-1|CAF31639.1| 221|Homo sapiens keratin associated protein
5-11 protein.
Length = 221
Score = 29.1 bits (62), Expect = 9.9
Identities = 13/34 (38%), Positives = 18/34 (52%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAAN 389
GS+ GC S S+ GC S S C+ CC ++
Sbjct: 128 GSKGGCGSCGGSKGGCGSYGCSQCSCCKPCCCSS 161
>AB126074-1|BAD20201.1| 221|Homo sapiens keratin associated protein
protein.
Length = 221
Score = 29.1 bits (62), Expect = 9.9
Identities = 13/34 (38%), Positives = 18/34 (52%)
Frame = -2
Query: 490 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAAN 389
GS+ GC S S+ GC S S C+ CC ++
Sbjct: 128 GSKGGCGSCGGSKGGCGSYGCSQCSCCKPCCCSS 161
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,674,107
Number of Sequences: 237096
Number of extensions: 1669301
Number of successful extensions: 4046
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 3788
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4019
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -