Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS315H02f
(456 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 114 1e-25
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 114 1e-25
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 114 1e-25
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 114 1e-25
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 114 1e-25
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 114 1e-25
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 114 1e-25
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 100 3e-21
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 99 4e-21
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 99 4e-21
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 99 4e-21
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 94 2e-19
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 94 2e-19
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 91 2e-18
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 91 2e-18
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 89 7e-18
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 87 2e-17
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 87 2e-17
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 87 2e-17
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 87 2e-17
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 87 2e-17
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 87 2e-17
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 87 2e-17
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 87 2e-17
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 87 2e-17
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 83 4e-16
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 83 4e-16
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 83 4e-16
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 83 4e-16
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 83 4e-16
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 83 4e-16
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 83 4e-16
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 80 4e-15
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 80 4e-15
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 80 4e-15
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 80 4e-15
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 80 4e-15
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 80 4e-15
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 4e-09
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.009
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 35 0.12
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 35 0.12
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 35 0.12
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 35 0.12
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 35 0.12
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 35 0.12
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 35 0.12
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 35 0.12
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 35 0.12
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 35 0.12
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 35 0.12
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.15
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.15
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.15
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.15
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 35 0.15
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 35 0.15
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 35 0.15
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 35 0.15
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 35 0.15
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 35 0.15
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 35 0.15
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 35 0.15
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.15
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 35 0.15
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 35 0.15
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 33 0.35
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 32 0.81
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 2.5
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 3.3
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 3.3
BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19 ... 29 5.7
AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein pr... 29 5.7
AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens ... 29 5.7
AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens ... 29 5.7
AY260762-1|AAP20225.1| 3567|Homo sapiens zinc finger homeodomain... 29 10.0
AK131462-1|BAD18607.1| 1103|Homo sapiens protein ( Homo sapiens ... 29 10.0
AK131399-1|BAD18546.1| 907|Homo sapiens protein ( Homo sapiens ... 29 10.0
AB083343-1|BAE96598.1| 3599|Homo sapiens zinc-finger homeodomain... 29 10.0
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 114 bits (275), Expect = 1e-25
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 11/115 (9%)
Frame = +3
Query: 138 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 284
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 125
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 100 bits (239), Expect = 3e-21
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 5/105 (4%)
Frame = +3
Query: 147 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 311
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 312 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFD 123
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 99 bits (238), Expect = 4e-21
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 5/105 (4%)
Frame = +3
Query: 147 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 311
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 312 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFD 123
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 99 bits (238), Expect = 4e-21
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 5/105 (4%)
Frame = +3
Query: 147 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 311
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 312 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFD 123
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 99 bits (238), Expect = 4e-21
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 5/105 (4%)
Frame = +3
Query: 147 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 311
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 312 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFD 123
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 94.3 bits (224), Expect = 2e-19
Identities = 44/98 (44%), Positives = 63/98 (64%), Gaps = 5/98 (5%)
Frame = +3
Query: 168 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 332
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 333 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFN 119
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 94.3 bits (224), Expect = 2e-19
Identities = 44/98 (44%), Positives = 63/98 (64%), Gaps = 5/98 (5%)
Frame = +3
Query: 168 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 332
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 333 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFN 123
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 90.6 bits (215), Expect = 2e-18
Identities = 52/118 (44%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 278
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 279 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFN 119
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 90.6 bits (215), Expect = 2e-18
Identities = 52/118 (44%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 278
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 279 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFN 119
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 89.0 bits (211), Expect = 7e-18
Identities = 51/118 (43%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 278
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 279 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFN 119
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 87.4 bits (207), Expect = 2e-17
Identities = 36/55 (65%), Positives = 43/55 (78%)
Frame = +3
Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDA 132
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 83.0 bits (196), Expect = 4e-16
Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 10/119 (8%)
Frame = +3
Query: 129 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 278
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSXQ 455
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ Q
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQ 124
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 79.8 bits (188), Expect = 4e-15
Identities = 47/103 (45%), Positives = 63/103 (61%), Gaps = 9/103 (8%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 318 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFN 116
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 79.8 bits (188), Expect = 4e-15
Identities = 47/103 (45%), Positives = 63/103 (61%), Gaps = 9/103 (8%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 318 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFN 116
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 79.8 bits (188), Expect = 4e-15
Identities = 47/103 (45%), Positives = 63/103 (61%), Gaps = 9/103 (8%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 318 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFN 113
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 79.8 bits (188), Expect = 4e-15
Identities = 47/103 (45%), Positives = 63/103 (61%), Gaps = 9/103 (8%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 318 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFN 116
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 79.8 bits (188), Expect = 4e-15
Identities = 47/103 (45%), Positives = 63/103 (61%), Gaps = 9/103 (8%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 318 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFN 116
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 79.8 bits (188), Expect = 4e-15
Identities = 47/103 (45%), Positives = 63/103 (61%), Gaps = 9/103 (8%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 318 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFN 116
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 4e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +3
Query: 165 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 317
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 318 VISIGTPPQSFKVVFDTGSSNL 383
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.009
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +3
Query: 156 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 308
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 309 YYGVISIGTP 338
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAV 39
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.12
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAV 88
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 34.7 bits (76), Expect = 0.15
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAV 132
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 33.5 bits (73), Expect = 0.35
Identities = 12/25 (48%), Positives = 16/25 (64%)
Frame = +3
Query: 375 SNLWVPSKKCHYTNIACLLHNKYDS 449
SN+WVPS KC AC+ H +D+
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDA 25
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 32.3 bits (70), Expect = 0.81
Identities = 13/21 (61%), Positives = 16/21 (76%)
Frame = +3
Query: 327 IGTPPQSFKVVFDTGSSNLWV 389
IGTPPQ +++ DTGSSN V
Sbjct: 3 IGTPPQKLQILVDTGSSNFAV 23
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 2.5
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -2
Query: 374 GSGVEYHLERLRRRADTDHSVVLSIK 297
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 3.3
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -1
Query: 300 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 148
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 3.3
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -1
Query: 447 CRTCCAANKRCWCSGTFWKAPRGWRIR 367
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 3.3
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -1
Query: 300 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 148
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 3.3
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -1
Query: 447 CRTCCAANKRCWCSGTFWKAPRGWRIR 367
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19
protein.
Length = 458
Score = 29.5 bits (63), Expect = 5.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 306 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 190
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 137 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 175
>AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein
protein.
Length = 339
Score = 29.5 bits (63), Expect = 5.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 306 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 190
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 18 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 56
>AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ32768 fis, clone TESTI2001879, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 5.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 306 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 190
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ31005 fis, clone HLUNG2000068, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 5.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 306 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 190
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AY260762-1|AAP20225.1| 3567|Homo sapiens zinc finger homeodomain 4
protein protein.
Length = 3567
Score = 28.7 bits (61), Expect = 10.0
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +1
Query: 370 DPPTSGCLPKSATTPTSLVC 429
+P T LPK ATTPT+ VC
Sbjct: 2796 EPKTLDTLPKPATTPTTEVC 2815
>AK131462-1|BAD18607.1| 1103|Homo sapiens protein ( Homo sapiens
cDNA FLJ16624 fis, clone TESTI4015442, moderately
similar to Mus musculus zinc finger homeodomain 4
(Zfh4-pending). ).
Length = 1103
Score = 28.7 bits (61), Expect = 10.0
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +1
Query: 370 DPPTSGCLPKSATTPTSLVC 429
+P T LPK ATTPT+ VC
Sbjct: 328 EPKTLDTLPKPATTPTTEVC 347
>AK131399-1|BAD18546.1| 907|Homo sapiens protein ( Homo sapiens
cDNA FLJ16492 fis, clone CTONG2028758, highly similar
to Mus musculus zfh-4 mRNA for zinc-finger homeodomain
protein 4. ).
Length = 907
Score = 28.7 bits (61), Expect = 10.0
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +1
Query: 370 DPPTSGCLPKSATTPTSLVC 429
+P T LPK ATTPT+ VC
Sbjct: 532 EPKTLDTLPKPATTPTTEVC 551
>AB083343-1|BAE96598.1| 3599|Homo sapiens zinc-finger homeodomain
protein 4 protein.
Length = 3599
Score = 28.7 bits (61), Expect = 10.0
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +1
Query: 370 DPPTSGCLPKSATTPTSLVC 429
+P T LPK ATTPT+ VC
Sbjct: 2824 EPKTLDTLPKPATTPTTEVC 2843
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,414,698
Number of Sequences: 237096
Number of extensions: 1504538
Number of successful extensions: 3205
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 3080
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3194
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 3815180866
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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