Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS314G03f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 137 2e-32
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 137 2e-32
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 137 2e-32
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 137 2e-32
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 137 2e-32
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 137 2e-32
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 137 2e-32
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 136 6e-32
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 129 7e-30
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 127 2e-29
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 127 2e-29
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 127 2e-29
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 127 2e-29
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 127 2e-29
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 127 2e-29
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 127 2e-29
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 127 2e-29
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 91 2e-18
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 88 2e-17
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 88 2e-17
Y14489-1|CAB54842.1| 92|Homo sapiens cytosolic serine hydroxym... 34 0.35
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 31 2.4
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 31 2.4
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 31 2.4
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 31 2.4
U34994-1|AAC50210.3| 4097|Homo sapiens DNA dependent protein kin... 31 3.2
L14837-1|AAA02891.1| 1736|Homo sapiens tight junction (zonula oc... 31 3.2
DQ015919-1|AAY22179.1| 1748|Homo sapiens tight junction protein ... 31 3.2
BC111712-1|AAI11713.1| 1748|Homo sapiens tight junction protein ... 31 3.2
AB208860-1|BAD92097.1| 726|Homo sapiens protein kinase, DNA-act... 31 3.2
BC101053-1|AAI01054.1| 792|Homo sapiens zinc finger protein 541... 29 7.5
BC101052-1|AAI01053.1| 792|Homo sapiens zinc finger protein 541... 29 7.5
BC101051-1|AAI01052.1| 792|Homo sapiens zinc finger protein 541... 29 7.5
BC101050-1|AAI01051.1| 792|Homo sapiens zinc finger protein 541... 29 7.5
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 63 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 122
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 123 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 176
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 180 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 236
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 409
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 409
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 409
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 409
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 409
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 137 bits (332), Expect = 2e-32
Identities = 66/114 (57%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFPGLQGGPHNH EF YQ QV+ N + L E L GY I
Sbjct: 296 VFPGLQGGPHNHAIAEVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 409
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 136 bits (328), Expect = 6e-32
Identities = 65/112 (58%), Positives = 78/112 (69%), Gaps = 1/112 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV+SV G++++Y+LES IN A
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSA 295
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGY 334
VFPGLQGGPHNH EF YQ QV+ N + L E L GY
Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGY 347
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 129 bits (311), Expect = 7e-30
Identities = 61/114 (53%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G++++Y E +IN A
Sbjct: 229 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREILYTFEDRINFA 288
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 289 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 342
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 346 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 402
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 238 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 297
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 298 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 351
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 355 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 411
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 259 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 318
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 319 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 432
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 235 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 294
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 295 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 348
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 352 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 408
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 259 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 318
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 319 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 432
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 249 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 308
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 309 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 362
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 366 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 422
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 259 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 318
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 319 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 432
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 259 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 318
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 319 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 432
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 127 bits (307), Expect = 2e-29
Identities = 61/114 (53%), Positives = 78/114 (68%), Gaps = 1/114 (0%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-KANGQKVMYDLESKINQA 178
VAA VIPSPF++ DIVTTTTHKTLRG R+G+IF+RKGV++V G+++ Y E +IN A
Sbjct: 259 VAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 318
Query: 179 VFPGLQGGPHNHXXXXXXXXXXXXXXXEFVEYQKQVIKNAQRLCEGLISRGYSI 340
VFP LQGGPHNH F EY QV+KNA+ + + L+ RGYS+
Sbjct: 319 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372
Score = 82.6 bits (195), Expect = 8e-16
Identities = 40/57 (70%), Positives = 43/57 (75%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
GTD HL LVDLR GL GA AERVLEL S+ NKNT PGD SA+ P G+RLG PALT
Sbjct: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALT 432
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 91.5 bits (217), Expect = 2e-18
Identities = 45/67 (67%), Positives = 51/67 (76%), Gaps = 1/67 (1%)
Frame = +3
Query: 324 RAGTL*-RRAGTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIR 500
RAG + R+ G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+R
Sbjct: 263 RAGMIFYRKGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLR 322
Query: 501 LGTPALT 521
LGTPALT
Sbjct: 323 LGTPALT 329
Score = 72.5 bits (170), Expect = 8e-13
Identities = 34/55 (61%), Positives = 43/55 (78%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDLESK 166
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKG ++ ++ DL SK
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKG----GSDNHLILVDLRSK 286
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 314 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 370
Score = 72.5 bits (170), Expect = 8e-13
Identities = 31/38 (81%), Positives = 36/38 (94%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGV 115
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV 273
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 88.2 bits (209), Expect = 2e-17
Identities = 41/57 (71%), Positives = 45/57 (78%)
Frame = +3
Query: 351 GTDVHLALVDLRGVGLRGAPAERVLELCSVACNKNTVPGDISALNPSGIRLGTPALT 521
G+D HL LVDLR G G AE+VLE CS+ACNKNT PGD SAL PSG+RLGTPALT
Sbjct: 314 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT 370
Score = 72.5 bits (170), Expect = 8e-13
Identities = 31/38 (81%), Positives = 36/38 (94%)
Frame = +2
Query: 2 VAAGVIPSPFEYCDIVTTTTHKTLRGPRAGVIFFRKGV 115
VAAGV+PSPFE+C +VTTTTHKTLRG RAG+IF+RKGV
Sbjct: 236 VAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV 273
>Y14489-1|CAB54842.1| 92|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 92
Score = 33.9 bits (74), Expect = 0.35
Identities = 15/18 (83%), Positives = 16/18 (88%)
Frame = +3
Query: 468 DISALNPSGIRLGTPALT 521
D SAL PSG+RLGTPALT
Sbjct: 1 DRSALRPSGLRLGTPALT 18
>AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppressor
protein protein.
Length = 1537
Score = 31.1 bits (67), Expect = 2.4
Identities = 10/16 (62%), Positives = 14/16 (87%)
Frame = +1
Query: 352 APTCTSRSWICAASGC 399
+PTC+SR +ICA+ GC
Sbjct: 915 SPTCSSREYICASDGC 930
>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
receptor related protein-deleted in tumor protein.
Length = 4599
Score = 31.1 bits (67), Expect = 2.4
Identities = 10/16 (62%), Positives = 14/16 (87%)
Frame = +1
Query: 352 APTCTSRSWICAASGC 399
+PTC+SR +ICA+ GC
Sbjct: 3591 SPTCSSREYICASDGC 3606
>AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.
Length = 1126
Score = 31.1 bits (67), Expect = 2.4
Identities = 10/16 (62%), Positives = 14/16 (87%)
Frame = +1
Query: 352 APTCTSRSWICAASGC 399
+PTC+SR +ICA+ GC
Sbjct: 449 SPTCSSREYICASDGC 464
>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
lipoprotein-related protein 1B variant protein.
Length = 1720
Score = 31.1 bits (67), Expect = 2.4
Identities = 10/16 (62%), Positives = 14/16 (87%)
Frame = +1
Query: 352 APTCTSRSWICAASGC 399
+PTC+SR +ICA+ GC
Sbjct: 712 SPTCSSREYICASDGC 727
>U34994-1|AAC50210.3| 4097|Homo sapiens DNA dependent protein kinase
catalytic subunit protein.
Length = 4097
Score = 30.7 bits (66), Expect = 3.2
Identities = 12/35 (34%), Positives = 20/35 (57%)
Frame = +1
Query: 292 ERAAVVRGFNIARVLYSDGRAPTCTSRSWICAASG 396
+RA +R +++ + SD RAP C + W+ SG
Sbjct: 3783 QRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSG 3817
>L14837-1|AAA02891.1| 1736|Homo sapiens tight junction (zonula
occludens) protein ZO-1 protein.
Length = 1736
Score = 30.7 bits (66), Expect = 3.2
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +2
Query: 2 VAAGVIPSP--FEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDLESKINQ 175
V G+IP+ E V T KT G RA FR G+RS K N +K DL ++ Q
Sbjct: 557 VERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFR-GLRSSKRNLRKSREDLSAQPVQ 615
Query: 176 AVFPGLQ 196
FP +
Sbjct: 616 TKFPAYE 622
>DQ015919-1|AAY22179.1| 1748|Homo sapiens tight junction protein 1
(zona occludens 1) protein.
Length = 1748
Score = 30.7 bits (66), Expect = 3.2
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +2
Query: 2 VAAGVIPSP--FEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDLESKINQ 175
V G+IP+ E V T KT G RA FR G+RS K N +K DL ++ Q
Sbjct: 569 VERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFR-GLRSSKRNLRKSREDLSAQPVQ 627
Query: 176 AVFPGLQ 196
FP +
Sbjct: 628 TKFPAYE 634
>BC111712-1|AAI11713.1| 1748|Homo sapiens tight junction protein 1
(zona occludens 1) protein.
Length = 1748
Score = 30.7 bits (66), Expect = 3.2
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +2
Query: 2 VAAGVIPSP--FEYCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDLESKINQ 175
V G+IP+ E V T KT G RA FR G+RS K N +K DL ++ Q
Sbjct: 569 VERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFR-GLRSSKRNLRKSREDLSAQPVQ 627
Query: 176 AVFPGLQ 196
FP +
Sbjct: 628 TKFPAYE 634
>AB208860-1|BAD92097.1| 726|Homo sapiens protein kinase,
DNA-activated, catalytic polypeptide variant protein.
Length = 726
Score = 30.7 bits (66), Expect = 3.2
Identities = 12/35 (34%), Positives = 20/35 (57%)
Frame = +1
Query: 292 ERAAVVRGFNIARVLYSDGRAPTCTSRSWICAASG 396
+RA +R +++ + SD RAP C + W+ SG
Sbjct: 412 QRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSG 446
>BC101053-1|AAI01054.1| 792|Homo sapiens zinc finger protein 541
protein.
Length = 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 348 AGTDVHLALVDLRGVG---LRGAPAERVLELCSVACNKNTVPG 467
AGTD H+A + + G + +RV ELC+VAC+ + +PG
Sbjct: 520 AGTDEHVASLVWKPWGDMMISSETQDRVTELCNVACS-SVMPG 561
>BC101052-1|AAI01053.1| 792|Homo sapiens zinc finger protein 541
protein.
Length = 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 348 AGTDVHLALVDLRGVG---LRGAPAERVLELCSVACNKNTVPG 467
AGTD H+A + + G + +RV ELC+VAC+ + +PG
Sbjct: 520 AGTDEHVASLVWKPWGDMMISSETQDRVTELCNVACS-SVMPG 561
>BC101051-1|AAI01052.1| 792|Homo sapiens zinc finger protein 541
protein.
Length = 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 348 AGTDVHLALVDLRGVG---LRGAPAERVLELCSVACNKNTVPG 467
AGTD H+A + + G + +RV ELC+VAC+ + +PG
Sbjct: 520 AGTDEHVASLVWKPWGDMMISSETQDRVTELCNVACS-SVMPG 561
>BC101050-1|AAI01051.1| 792|Homo sapiens zinc finger protein 541
protein.
Length = 792
Score = 29.5 bits (63), Expect = 7.5
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 348 AGTDVHLALVDLRGVG---LRGAPAERVLELCSVACNKNTVPG 467
AGTD H+A + + G + +RV ELC+VAC+ + +PG
Sbjct: 520 AGTDEHVASLVWKPWGDMMISSETQDRVTELCNVACS-SVMPG 561
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 71,512,099
Number of Sequences: 237096
Number of extensions: 1462953
Number of successful extensions: 3864
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 3587
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3838
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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