Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS314E08f
(521 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q6Q2D6 Cluster: Serpin-4A; n=3; Obtectomera|Rep: Serpin... 50 2e-05
UniRef50_Q6Q2D3 Cluster: Serpin-5B; n=2; Obtectomera|Rep: Serpin... 48 1e-04
UniRef50_Q16P31 Cluster: Serine protease inhibitor, serpin; n=1;... 46 7e-04
UniRef50_UPI00015B4C80 Cluster: PREDICTED: similar to Antichymot... 45 0.001
UniRef50_Q8IW75 Cluster: Serpin A12 precursor; n=13; Eutheria|Re... 45 0.001
UniRef50_UPI0001555D13 Cluster: PREDICTED: similar to corticoste... 44 0.003
UniRef50_Q7TMB9 Cluster: Liver regeneration protein lrryan; n=2;... 42 0.011
UniRef50_UPI0000DA2B23 Cluster: PREDICTED: similar to Alpha-1-an... 41 0.020
UniRef50_Q26058 Cluster: Putative serine proteinase inhibitor pr... 41 0.020
UniRef50_UPI00015560AF Cluster: PREDICTED: hypothetical protein,... 40 0.035
UniRef50_UPI000155529C Cluster: PREDICTED: similar to Serpin pep... 40 0.035
UniRef50_P01011 Cluster: Alpha-1-antichymotrypsin precursor (ACT... 40 0.035
UniRef50_UPI0000F2B319 Cluster: PREDICTED: hypothetical protein;... 39 0.060
UniRef50_UPI00015B561F Cluster: PREDICTED: similar to serpin; n=... 38 0.11
UniRef50_Q4A8U8 Cluster: Putative uncharacterized protein; n=5; ... 38 0.14
UniRef50_Q4T3D2 Cluster: Chromosome undetermined SCAF10097, whol... 37 0.24
UniRef50_Q9KB26 Cluster: BH2109 protein; n=1; Bacillus haloduran... 37 0.32
UniRef50_Q66IN0 Cluster: MGC86518 protein; n=2; Xenopus|Rep: MGC... 36 0.56
UniRef50_UPI00015B561E Cluster: PREDICTED: similar to serpin 6; ... 35 0.98
UniRef50_UPI0001555E35 Cluster: PREDICTED: similar to alpha,-ant... 35 1.3
UniRef50_Q5M911 Cluster: Serpina3k-prov protein; n=10; Xenopus|R... 34 1.7
UniRef50_A5UVP3 Cluster: Putative uncharacterized protein precur... 34 1.7
UniRef50_P08185 Cluster: Corticosteroid-binding globulin precurs... 34 1.7
UniRef50_UPI00006CC291 Cluster: hypothetical protein TTHERM_0066... 34 2.3
UniRef50_P19338 Cluster: Nucleolin; n=39; Deuterostomia|Rep: Nuc... 34 2.3
UniRef50_UPI000054A214 Cluster: PREDICTED: hypothetical protein;... 33 4.0
UniRef50_UPI00004484CA Cluster: PREDICTED: similar to alpha-1-an... 33 4.0
UniRef50_Q5SJJ4 Cluster: Putative uncharacterized protein TTHA10... 33 4.0
UniRef50_Q010K7 Cluster: Chromosome 10 contig 1, DNA sequence; n... 33 4.0
UniRef50_UPI0000498FC4 Cluster: damaged DNA binding protein; n=2... 33 5.2
UniRef50_Q005M7 Cluster: Serpin 8; n=2; Anopheles gambiae|Rep: S... 33 5.2
UniRef50_UPI0000D56DBC Cluster: PREDICTED: similar to CG9453-PJ,... 32 6.9
UniRef50_Q7K8Y5 Cluster: Serpin 4; n=11; Sophophora|Rep: Serpin ... 32 6.9
UniRef50_Q22551 Cluster: Groundhog (Hedgehog-like family) protei... 32 6.9
UniRef50_A0CDU9 Cluster: Chromosome undetermined scaffold_17, wh... 32 6.9
UniRef50_Q75DM1 Cluster: ABL004Wp; n=1; Eremothecium gossypii|Re... 32 6.9
UniRef50_UPI00015B414F Cluster: PREDICTED: similar to serpin 3a;... 32 9.2
UniRef50_A4CNJ6 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_A0ZSH9 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_Q59L91 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
>UniRef50_Q6Q2D6 Cluster: Serpin-4A; n=3; Obtectomera|Rep: Serpin-4A
- Bombyx mori (Silk moth)
Length = 410
Score = 50.4 bits (115), Expect = 2e-05
Identities = 28/120 (23%), Positives = 61/120 (50%), Gaps = 3/120 (2%)
Frame = +3
Query: 171 ETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHP-HKCFNNKIFKLLRDQKETA 347
++ + +MS ++ WT+++ ++ GA+ T ++I RL H F+ + +
Sbjct: 50 QSKGNLIMSPITVWTVLAVIAEGASGNTRRQINHALRLQAKHTNVTRSEFQKISEWLRVN 109
Query: 348 VGTLE--KSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVTH 521
T+E K +A+ VD++ + Q+ F + + + L+F+D +SA +N ++ TH
Sbjct: 110 TNTIELAKINAIIVDKQRLPQQDFHDNAKTYYETDMITLNFEDAQNSANLLNSAISNFTH 169
>UniRef50_Q6Q2D3 Cluster: Serpin-5B; n=2; Obtectomera|Rep: Serpin-5B
- Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Length = 396
Score = 48.4 bits (110), Expect = 1e-04
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 4/129 (3%)
Frame = +3
Query: 138 FSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNKIF 317
FS +L +T H V+S WTL++ ++ GAT + +++ + L + + +
Sbjct: 28 FSIELLYHTQLQTGGHVVISPFGIWTLMTGIALGATGNSYKQLSRAFILPKNPDTLTEGY 87
Query: 318 KLLR----DQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSA 485
K L D AV L + +F+D V F++ +QK +KVL F D +SA
Sbjct: 88 KSLTNVVLDPSSNAV-ALTSKNFVFLDNDFNVYPDFRLRLQKDFSAAIKVLDFGDP-NSA 145
Query: 486 ATINQYVNE 512
N Y+ +
Sbjct: 146 RIANTYIEK 154
>UniRef50_Q16P31 Cluster: Serine protease inhibitor, serpin; n=1;
Aedes aegypti|Rep: Serine protease inhibitor, serpin -
Aedes aegypti (Yellowfever mosquito)
Length = 454
Score = 45.6 bits (103), Expect = 7e-04
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 3/137 (2%)
Frame = +3
Query: 114 YFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPH 293
+FK+ ND V T ++ +S LS WTL++ LS GA ETL+EI +V +
Sbjct: 78 FFKQVSLTVDNDRNV-----TTTNIFVSPLSVWTLLALLSEGAEGETLREILEVMSVQDQ 132
Query: 294 KCFNNKIFKLLRDQKETAVGTLEKSSA--LFVDERMIVQEKFQVDVQK-TGVCGVKVLSF 464
+ FK ++ +E SSA +F D+ V+ F+ V G + L F
Sbjct: 133 NLIKHH-FKSFQETINVKANGVEISSAQFMFTDKNHPVRHDFEHIVDTYYGENLFEALDF 191
Query: 465 DDTISSAATINQYVNEV 515
+ S Y+N+V
Sbjct: 192 SSSNESLRDSYNYINKV 208
>UniRef50_UPI00015B4C80 Cluster: PREDICTED: similar to
Antichymotrypsin-2 (Antichymotrypsin II) (ACHY-II); n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
Antichymotrypsin-2 (Antichymotrypsin II) (ACHY-II) -
Nasonia vitripennis
Length = 409
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 2/162 (1%)
Frame = +3
Query: 39 FISLISILLLTPGIYGQCNLKTAGAYFKRSLYEFSNDLAVRIN--YETDSHFVMSGLSAW 212
F LIS L+++ G+ N + + S +F+++L + E + S LSA+
Sbjct: 12 FCFLISQLVISTGV--NMNSELNFLHISNSCSDFTSNLFQELTSKQEDTENVASSSLSAY 69
Query: 213 TLISALSFGATDETLQEIYQVARLHPHKCFNNKIFKLLRDQKETAVGTLEKSSALFVDER 392
++S L G ET +EI L+ ++ L L+ ++ ++VD
Sbjct: 70 IILSLLLHGTDGETREEIKSGLNLNDLDKTQEELQSLFMHLNNVTDADLQLTNGIYVDSN 129
Query: 393 MIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
+++ F Q+ V+ + F ++ +A IN++V E T
Sbjct: 130 FQLRDCFMSKSQEYYQTSVEKMIFQNSDVAANQINEWVKEKT 171
>UniRef50_Q8IW75 Cluster: Serpin A12 precursor; n=13; Eutheria|Rep:
Serpin A12 precursor - Homo sapiens (Human)
Length = 414
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Frame = +3
Query: 168 YETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVA--RLHPHKCFNNKIFKLLRD-QK 338
Y + +S LS T S L GA D TL EI Q R P K + ++ + +
Sbjct: 66 YNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYIIHELTQ 125
Query: 339 ETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
+T L + LF+D+R+ Q KF D + + +F + + IN ++++ T
Sbjct: 126 KTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKT 185
Query: 519 H 521
H
Sbjct: 186 H 186
>UniRef50_UPI0001555D13 Cluster: PREDICTED: similar to
corticosteroid-binding globulin - sheep, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
corticosteroid-binding globulin - sheep, partial -
Ornithorhynchus anatinus
Length = 431
Score = 43.6 bits (98), Expect = 0.003
Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Frame = +3
Query: 171 ETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNKI---FKLLRDQKE 341
E + +S +S + LS GA + TL +I + R + I F LR + +
Sbjct: 148 EPGKNVFVSPVSISIAFALLSLGAKNATLAQILEGFRFNTTVGRAEAIHEGFHHLRRRLK 207
Query: 342 TAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVTH 521
+ L+ SALFVDE++ + E F D K ++F D IN+YV TH
Sbjct: 208 ASDAALDLGSALFVDEKIKILELFVTDATKYYEAEAHPVNFGDLEGVRKQINEYVANQTH 267
>UniRef50_Q7TMB9 Cluster: Liver regeneration protein lrryan; n=2;
Rattus norvegicus|Rep: Liver regeneration protein lrryan
- Rattus norvegicus (Rat)
Length = 611
Score = 41.5 bits (93), Expect = 0.011
Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 8/149 (5%)
Frame = +3
Query: 96 LKTAGAYFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQ- 272
L ++ F SLY+ LA+R D + V S LS ++ LS GA D T++EI +
Sbjct: 25 LASSNTDFALSLYK---KLALR---NPDKNVVFSPLSISAALTILSLGAKDSTMEEILEG 78
Query: 273 -------VARLHPHKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQK 431
+ H+ F + + +L + + + + T SALF+D+ + +FQ +
Sbjct: 79 LKFNLTEITEEEIHQGFGHLLQRLSQPEDQVEINT---GSALFIDKEQPILSEFQEKTRA 135
Query: 432 TGVCGVKVLSFDDTISSAATINQYVNEVT 518
+ F + IN YV+ T
Sbjct: 136 LYQAEAFIADFKQPNEAKKLINDYVSNQT 164
>UniRef50_UPI0000DA2B23 Cluster: PREDICTED: similar to
Alpha-1-antitrypsin-related protein precursor; n=1;
Rattus norvegicus|Rep: PREDICTED: similar to
Alpha-1-antitrypsin-related protein precursor - Rattus
norvegicus
Length = 388
Score = 40.7 bits (91), Expect = 0.020
Identities = 25/77 (32%), Positives = 41/77 (53%)
Frame = +3
Query: 291 HKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDD 470
H+CF + +L T T++ S+LF D+++ + +KF DV++ V L+F D
Sbjct: 86 HECFQQLTY-ILHLPDHTPQLTMD--SSLFTDQKLKLMDKFVEDVRRLYHSKVIALNFKD 142
Query: 471 TISSAATINQYVNEVTH 521
T + IN+YV TH
Sbjct: 143 TQRAQNQINEYVEGETH 159
>UniRef50_Q26058 Cluster: Putative serine proteinase inhibitor
precursor; n=1; Pacifastacus leniusculus|Rep: Putative
serine proteinase inhibitor precursor - Pacifastacus
leniusculus (Signal crayfish)
Length = 429
Score = 40.7 bits (91), Expect = 0.020
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 5/132 (3%)
Frame = +3
Query: 138 FSNDLAVRINYE-TDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARL----HPHKCF 302
F DL +N T S+F S S W + FG++ T Q++ +V RL H +
Sbjct: 40 FGVDLFKELNPTGTTSNFFFSPYSIWNSLVLAYFGSSGGTRQQLQKVLRLGDPAHTLATY 99
Query: 303 NNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISS 482
Q T+ ++ ++ ++VDE+ ++E V+ V+ + F +
Sbjct: 100 RALSHLYAERQANTSDYVIDLANRVYVDEKFPLRE----CVKGVLFQEVQAIDFGQAEEA 155
Query: 483 AATINQYVNEVT 518
AA INQ VNE T
Sbjct: 156 AARINQLVNETT 167
>UniRef50_UPI00015560AF Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 456
Score = 39.9 bits (89), Expect = 0.035
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 8/116 (6%)
Frame = +3
Query: 195 SGLSAWTLISALSFGATDETLQEIYQ--------VARLHPHKCFNNKIFKLLRDQKETAV 350
S LS T ++ LS GA TL +I + ++ H+ F + + L + +
Sbjct: 110 SPLSISTSLAMLSLGAQSATLTQILEGLCFNLSHISEREIHEGFQHIVRTLNLTSNDLEI 169
Query: 351 GTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
++LFV ++M +QEKFQ D+Q+ +F D+ + IN YV + T
Sbjct: 170 NM---GNSLFVRKQMKLQEKFQGDLQRLYAAEALSTNFKDSAGAEKQINAYVEKKT 222
>UniRef50_UPI000155529C Cluster: PREDICTED: similar to Serpin
peptidase inhibitor, clade A (alpha-1 antiproteinase,
antitrypsin), member 4; n=2; Mammalia|Rep: PREDICTED:
similar to Serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 4 - Ornithorhynchus
anatinus
Length = 498
Score = 39.9 bits (89), Expect = 0.035
Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 10/130 (7%)
Frame = +3
Query: 162 INYETDSHFVMSGLSAWTLISALSFGATDETLQEIY--------QVARLHPHKCFNNKIF 317
I+ D + +S LS T ++ LS GA TL ++ Q++ H F + I
Sbjct: 70 ISERPDKNVFLSPLSISTTLAMLSLGARSATLTQMLEGLHFNLTQISEREIHDGFQHIIR 129
Query: 318 KL-LRDQK-ETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAAT 491
L L +Q ET +G ++LF+DER+ +E F +++ F D + +
Sbjct: 130 TLNLHNQNLETHLG-----NSLFLDERLTPKEAFLEGIKELYATEAFKTDFQDAVGAEKQ 184
Query: 492 INQYVNEVTH 521
IN +V + TH
Sbjct: 185 INDHVRKETH 194
>UniRef50_P01011 Cluster: Alpha-1-antichymotrypsin precursor (ACT)
(Cell growth-inhibiting gene 24/25 protein) [Contains:
Alpha-1-antichymotrypsin His-Pro-less]; n=101;
Theria|Rep: Alpha-1-antichymotrypsin precursor (ACT)
(Cell growth-inhibiting gene 24/25 protein) [Contains:
Alpha-1-antichymotrypsin His-Pro-less] - Homo sapiens
(Human)
Length = 423
Score = 39.9 bits (89), Expect = 0.035
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = +3
Query: 75 GIYGQCNLKTAGAYFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDET 254
G + L +A F SLY+ L ++ D + + S LS T ++ LS GA + T
Sbjct: 42 GTHVDLGLASANVDFAFSLYK---QLVLKA---PDKNVIFSPLSISTALAFLSLGAHNTT 95
Query: 255 LQEIYQVARLHPHKCFNNKIFK----LLRDQKETAVGT-LEKSSALFVDERMIVQEKFQV 419
L EI + + + + +I + LLR +++ L +A+FV E++ + ++F
Sbjct: 96 LTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTE 155
Query: 420 DVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
D ++ F D+ ++ IN YV T
Sbjct: 156 DAKRLYGSEAFATDFQDSAAAKKLINDYVKNGT 188
>UniRef50_UPI0000F2B319 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 429
Score = 39.1 bits (87), Expect = 0.060
Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Frame = +3
Query: 162 INYETDSHFVMSGLSAWTLISALSFGATDETLQEI-----YQVARLHP---HKCFNNKIF 317
++ +D + + S L ++S L+ G T +I + + + HK F N I
Sbjct: 67 VSQGSDLNVIFSPLRVSMILSLLTLGTHSVTRAQILMGLGFNLKEIQEDTIHKFFQNLIL 126
Query: 318 KLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATIN 497
L + L SALFV+ER+ + E F + + T + + F + + IN
Sbjct: 127 NLNLPSPDL---DLYMGSALFVEERLRLLEDFSQNAKTTYMSETLNIDFQYPVRAQKRIN 183
Query: 498 QYVNEVTH 521
Y++E TH
Sbjct: 184 DYISEQTH 191
>UniRef50_UPI00015B561F Cluster: PREDICTED: similar to serpin; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to serpin -
Nasonia vitripennis
Length = 426
Score = 38.3 bits (85), Expect = 0.11
Identities = 21/64 (32%), Positives = 35/64 (54%)
Frame = +3
Query: 105 AGAYFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARL 284
A A +S F+ND + +TD +FV S LSA +++ ++GA +T +E+ + L
Sbjct: 9 AVAQVAKSAQSFTNDFHKNVAGKTDGNFVSSALSAHVVLAMAAYGADGKTKEEMQRTLHL 68
Query: 285 HPHK 296
P K
Sbjct: 69 -PEK 71
>UniRef50_Q4A8U8 Cluster: Putative uncharacterized protein; n=5;
Mycoplasma hyopneumoniae|Rep: Putative uncharacterized
protein - Mycoplasma hyopneumoniae (strain 7448)
Length = 1566
Score = 37.9 bits (84), Expect = 0.14
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +3
Query: 96 LKTAGAYFKRSLYEFSNDLAVRINYETDSHFVMSG--LSAWTLISALSFGATDETLQEIY 269
L+ G K S + N L+V+ NY G LS W +I A+ A D + EIY
Sbjct: 200 LQMLGLDTKLSKFRIDNSLSVKENYNNFKKLFSEGNNLSNWEMIDAIQLSAFDYSKIEIY 259
Query: 270 QVARLHPHKCFNNKIFK 320
+ K NN +K
Sbjct: 260 TDLVENQEKIINNNFYK 276
>UniRef50_Q4T3D2 Cluster: Chromosome undetermined SCAF10097, whole
genome shotgun sequence; n=8; Percomorpha|Rep:
Chromosome undetermined SCAF10097, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 401
Score = 37.1 bits (82), Expect = 0.24
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 4/112 (3%)
Frame = +3
Query: 195 SGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNKI---FKLLRDQ-KETAVGTLE 362
S LS ++AL+ GA ET Q++++ L ++ F+ L +Q + T+
Sbjct: 62 SPLSVSVALAALAVGARGETHQQLFRGLGLSNTSLSQAQVDQAFQSLFEQTRRTSSQVTR 121
Query: 363 KSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
+ +A+FVD Q F ++++ + F + S TIN+YV E T
Sbjct: 122 EGTAVFVDHLFKAQPGFLHTLKQSYFADGFAVDFSKSSESTDTINKYVKEKT 173
>UniRef50_Q9KB26 Cluster: BH2109 protein; n=1; Bacillus
halodurans|Rep: BH2109 protein - Bacillus halodurans
Length = 525
Score = 36.7 bits (81), Expect = 0.32
Identities = 23/92 (25%), Positives = 45/92 (48%)
Frame = +3
Query: 45 SLISILLLTPGIYGQCNLKTAGAYFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLIS 224
S+ S+ + P GQ KT G YFK L + + A ++ +TD + + +
Sbjct: 442 SIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTD-------MRVYEVAE 494
Query: 225 ALSFGATDETLQEIYQVARLHPHKCFNNKIFK 320
+ FG+TD + + ++ ++ P + + NK+ K
Sbjct: 495 RVGFGSTDYFVTQFEKINKMTPTE-YRNKLLK 525
>UniRef50_Q66IN0 Cluster: MGC86518 protein; n=2; Xenopus|Rep:
MGC86518 protein - Xenopus laevis (African clawed frog)
Length = 705
Score = 35.9 bits (79), Expect = 0.56
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 2/136 (1%)
Frame = +3
Query: 117 FKRSLYEFSNDLAVRINYETDS-HFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPH 293
F +S+ FS DL I+ E+ VMS S + LS G+ E +++ + +
Sbjct: 329 FSQSITSFSIDLLKEIDPESKKPSVVMSPFSIALGLLQLSLGSGKEMEEKLMKTLHVESL 388
Query: 294 KCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDT 473
C +NK+ K +R KE L ++ +++ + +++ F +K G K L+ +T
Sbjct: 389 HCLHNKL-KTVR--KELTKSILRTATRIYLKKGFKIKKSFLKRSEKW--YGSKPLNLANT 443
Query: 474 -ISSAATINQYVNEVT 518
+ +IN++V +VT
Sbjct: 444 KKQNLDSINKWVKDVT 459
>UniRef50_UPI00015B561E Cluster: PREDICTED: similar to serpin 6;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
serpin 6 - Nasonia vitripennis
Length = 533
Score = 35.1 bits (77), Expect = 0.98
Identities = 28/131 (21%), Positives = 58/131 (44%), Gaps = 2/131 (1%)
Frame = +3
Query: 135 EFSNDLAVRINYETDS-HFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNK 311
+FS+D + ++ E + + S LSA ++S +FGA T ++ Q + + +
Sbjct: 170 KFSDDSSAVVSAENKGKNLISSPLSAHVVLSMAAFGAGGNTAVQMRQSLHMPADDVVSKQ 229
Query: 312 IFKLLRDQKETAVG-TLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAA 488
F+ L D TLE ++ +++ + ++ ++ T + SA
Sbjct: 230 GFENLIDTLNNVENVTLEVANKMYLANNLKLKSDYKSLTSGTFRSEATEIDTSKPAESAK 289
Query: 489 TINQYVNEVTH 521
+N +V+E TH
Sbjct: 290 VVNDWVDERTH 300
>UniRef50_UPI0001555E35 Cluster: PREDICTED: similar to
alpha,-antitrypsin-like protein; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to
alpha,-antitrypsin-like protein - Ornithorhynchus
anatinus
Length = 403
Score = 34.7 bits (76), Expect = 1.3
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 6/138 (4%)
Frame = +3
Query: 126 SLYEFSNDLAVRINYETDS-HFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCF 302
++ F+ +L ++ +++S + S LS + + LS GA T +I + + +
Sbjct: 86 NIANFALNLYQQLASDSNSTNIFFSPLSISSAFALLSLGARSVTHTQILEGLGFNLTRTS 145
Query: 303 NNKIFK----LLRDQKETAVGT-LEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFD 467
+I K ++R G L+ SALFVD ++ + E+F D + F
Sbjct: 146 EAEIHKGFQDIVRSLARANSGLQLDTGSALFVDNKLKLLERFLEDAKNLYSSEAFSTDFK 205
Query: 468 DTISSAATINQYVNEVTH 521
D + IN YV + TH
Sbjct: 206 DLAVAKKQINDYVEKGTH 223
>UniRef50_Q5M911 Cluster: Serpina3k-prov protein; n=10; Xenopus|Rep:
Serpina3k-prov protein - Xenopus tropicalis (Western
clawed frog) (Silurana tropicalis)
Length = 436
Score = 34.3 bits (75), Expect = 1.7
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Frame = +3
Query: 132 YEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHP------- 290
+ FS + ++ T++ F+ S +S T+ + LS GA TL +I + + +
Sbjct: 76 FGFSLYRQIAADHPTENIFI-SPVSISTVFAMLSLGARSNTLNQIIEGLKFNRSELTEEE 134
Query: 291 -HKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFD 467
HK F + + +L D L +ALF+D+ + + +KF D ++ F
Sbjct: 135 MHKGFQH-LLHMLNDPNSKV--QLNSGNALFIDKDLQLIQKFVEDSKQFYEAETFSTDFH 191
Query: 468 DTISSAATINQYVNEVT 518
+T + IN Y T
Sbjct: 192 NTEEATKQINTYAENKT 208
>UniRef50_A5UVP3 Cluster: Putative uncharacterized protein
precursor; n=2; Roseiflexus|Rep: Putative
uncharacterized protein precursor - Roseiflexus sp. RS-1
Length = 947
Score = 34.3 bits (75), Expect = 1.7
Identities = 15/36 (41%), Positives = 20/36 (55%)
Frame = +3
Query: 51 ISILLLTPGIYGQCNLKTAGAYFKRSLYEFSNDLAV 158
+ +LLL P +YG L+T G F+R F N L V
Sbjct: 454 LDLLLLVPAVYGVYQLQTGGGLFQRGADPFGNPLLV 489
>UniRef50_P08185 Cluster: Corticosteroid-binding globulin precursor;
n=22; Eutheria|Rep: Corticosteroid-binding globulin
precursor - Homo sapiens (Human)
Length = 405
Score = 34.3 bits (75), Expect = 1.7
Identities = 28/101 (27%), Positives = 46/101 (45%)
Frame = +3
Query: 216 LISALSFGATDETLQEIYQVARLHPHKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERM 395
L+ L F T+ + EI+Q + H H+ F L E +G +ALF+D +
Sbjct: 89 LLQGLGFNLTERSETEIHQGFQ-HLHQLFAKSDTSL-----EMTMG-----NALFLDGSL 137
Query: 396 IVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
+ E F D++ V ++F D +++ IN YV T
Sbjct: 138 ELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKT 178
>UniRef50_UPI00006CC291 Cluster: hypothetical protein
TTHERM_00660150; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00660150 - Tetrahymena
thermophila SB210
Length = 703
Score = 33.9 bits (74), Expect = 2.3
Identities = 28/142 (19%), Positives = 60/142 (42%)
Frame = +3
Query: 87 QCNLKTAGAYFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEI 266
Q +L AYF++ +YE L V++N D + + W + +E +++
Sbjct: 221 QNDLSENKAYFEKKIYELEKKLLVQLNTYDDKISDVEKNTLWRIQDC------EEIIKK- 273
Query: 267 YQVARLHPHKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCG 446
+V + + CF K+LRD K + G E+ ++ D ++ + +K
Sbjct: 274 -RVTQDYVDNCFTAFQEKILRDMKASTAGDSERIDSIQQDLAFKIKMLQESFTEKQNSLK 332
Query: 447 VKVLSFDDTISSAATINQYVNE 512
+ D+ ++ A + + +E
Sbjct: 333 QNIKEVDEKLAKKAMMKEIFDE 354
>UniRef50_P19338 Cluster: Nucleolin; n=39; Deuterostomia|Rep:
Nucleolin - Homo sapiens (Human)
Length = 710
Score = 33.9 bits (74), Expect = 2.3
Identities = 18/51 (35%), Positives = 30/51 (58%)
Frame = +3
Query: 126 SLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVA 278
SLY ++ + +Y + SG S ++S LS+ AT+ETLQE+++ A
Sbjct: 460 SLY-YTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKA 509
>UniRef50_UPI000054A214 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 780
Score = 33.1 bits (72), Expect = 4.0
Identities = 20/58 (34%), Positives = 28/58 (48%)
Frame = +1
Query: 250 KLCKKSTRLQGCTLINASITKYSSFSGIRRKLPSGRWRKAQLCSLTRG*SCKKNSRWT 423
K C+K + +GC + S + Y S GI R LP + A L L+R SC W+
Sbjct: 213 KRCQKGKKCEGCDSLRVSDSDYESVCGIPRHLPEQAF--ATL-GLSREKSCSMPLHWS 267
>UniRef50_UPI00004484CA Cluster: PREDICTED: similar to
alpha-1-antitrypsin; n=4; Gallus gallus|Rep: PREDICTED:
similar to alpha-1-antitrypsin - Gallus gallus
Length = 432
Score = 33.1 bits (72), Expect = 4.0
Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Frame = +3
Query: 174 TDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNKI---FKLLRDQKET 344
TD + S +S T ++ L+ GA TL +I + + K + +I F L
Sbjct: 79 TDQNIFFSPISISTSLAMLALGAKSVTLTQILEGLAFNLKKTQDQEIHEGFCQLLHMLNR 138
Query: 345 AVGTLEKS--SALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
+ L S + LF++E + +KF D + V F+++ + IN Y+ E T
Sbjct: 139 SDSDLHLSLGNTLFIEETLKPLQKFLDDAKSFYQSEVLSADFNNSSGAENQINSYIEEKT 198
Query: 519 H 521
+
Sbjct: 199 N 199
>UniRef50_Q5SJJ4 Cluster: Putative uncharacterized protein TTHA1014;
n=1; Thermus thermophilus HB8|Rep: Putative
uncharacterized protein TTHA1014 - Thermus thermophilus
(strain HB8 / ATCC 27634 / DSM 579)
Length = 893
Score = 33.1 bits (72), Expect = 4.0
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +3
Query: 141 SNDLAVRI-NYETDSHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNKIF 317
++ LA R+ Y F++ ++ L+SAL+ G T + LQE+Y+ +PH K +
Sbjct: 675 ASTLAKRVYEYLKAREFLLERIAPRHLLSALAQGETGKPLQEVYEAFLRYPHLPV-LKGW 733
Query: 318 KLLRDQKETAVGTLEKSSALFVDERMIVQE 407
++L ++ G E + L V ER QE
Sbjct: 734 EVL--EEAVRKGVAEGTFGLRVGERYYFQE 761
>UniRef50_Q010K7 Cluster: Chromosome 10 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 10 contig 1, DNA
sequence - Ostreococcus tauri
Length = 375
Score = 33.1 bits (72), Expect = 4.0
Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = -2
Query: 496 LIVAAEEIVSSKDRTLTPQTPVFCTSTWNFSCTIILSSTNKA-ELFSSVPTAVSF*SRRS 320
L +AE + S+ +R+ + + + C ST F C+ LS + A +L S+ P+A + +RRS
Sbjct: 84 LASSAERLASTSNRSCSLRASLNCVSTLAFPCSTSLSLSRIACDLRSNFPSAFANSTRRS 143
Query: 319 L 317
+
Sbjct: 144 I 144
>UniRef50_UPI0000498FC4 Cluster: damaged DNA binding protein; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: damaged DNA binding
protein - Entamoeba histolytica HM-1:IMSS
Length = 1088
Score = 32.7 bits (71), Expect = 5.2
Identities = 15/55 (27%), Positives = 30/55 (54%)
Frame = +3
Query: 294 KCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVL 458
K N ++ + K+ ++EK +F +R+I +F+V +Q+ G C VK++
Sbjct: 811 KDVNGAVYSMKTLLKKYLAMSIEKKLVVFEYQRVITNGEFEVKLQEKGSCNVKLI 865
>UniRef50_Q005M7 Cluster: Serpin 8; n=2; Anopheles gambiae|Rep:
Serpin 8 - Anopheles gambiae (African malaria mosquito)
Length = 434
Score = 32.7 bits (71), Expect = 5.2
Identities = 16/61 (26%), Positives = 31/61 (50%)
Frame = +3
Query: 84 GQCNLKTAGAYFKRSLYEFSNDLAVRINYETDSHFVMSGLSAWTLISALSFGATDETLQE 263
G L+ + F Y++ +L T ++ ++S SAW L++ ++ GA+ TL E
Sbjct: 46 GVDRLQRSSQKFALQFYQYVTELVDYNPNVTTTNIIVSPFSAWNLLTLITEGASGRTLDE 105
Query: 264 I 266
+
Sbjct: 106 L 106
>UniRef50_UPI0000D56DBC Cluster: PREDICTED: similar to CG9453-PJ,
isoform J; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG9453-PJ, isoform J - Tribolium castaneum
Length = 386
Score = 32.3 bits (70), Expect = 6.9
Identities = 29/110 (26%), Positives = 57/110 (51%)
Frame = +3
Query: 189 VMSGLSAWTLISALSFGATDETLQEIYQVARLHPHKCFNNKIFKLLRDQKETAVGTLEKS 368
++S LSA T+++ G DET QEI V L P+ N+I L + T +G ++ +
Sbjct: 50 LISPLSAETVLALAQSGCGDETSQEIRTVLHL-PND--QNQIENLYKTVLPT-LG-VQSA 104
Query: 369 SALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
+ ++V E+ ++ +F ++ + ++F +A +NQ+V + T
Sbjct: 105 NKIYVKEKFTIRSEFTKIAKEVFGSDCENVNFSKE-EAAGIMNQWVEQQT 153
>UniRef50_Q7K8Y5 Cluster: Serpin 4; n=11; Sophophora|Rep: Serpin 4 -
Drosophila melanogaster (Fruit fly)
Length = 424
Score = 32.3 bits (70), Expect = 6.9
Identities = 30/139 (21%), Positives = 68/139 (48%), Gaps = 4/139 (2%)
Frame = +3
Query: 117 FKRSLYEFSNDLAVRIN-YETDSHFVMSGLSAWTLISALSFGATDETLQEIYQ---VARL 284
F R L FS ++ +++ + + V S S T + GA +ET ++ Q +A
Sbjct: 41 FARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASS 100
Query: 285 HPHKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSF 464
P + ++ ++L +++ + L ++ +FV + ++++F + K + + + F
Sbjct: 101 DPEQIAHS-FHQVLAAYQDSQI--LRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDF 157
Query: 465 DDTISSAATINQYVNEVTH 521
+ +AATIN +V + T+
Sbjct: 158 SKNVQAAATINNWVEQRTN 176
>UniRef50_Q22551 Cluster: Groundhog (Hedgehog-like family) protein
6; n=2; Caenorhabditis|Rep: Groundhog (Hedgehog-like
family) protein 6 - Caenorhabditis elegans
Length = 559
Score = 32.3 bits (70), Expect = 6.9
Identities = 16/36 (44%), Positives = 21/36 (58%)
Frame = +1
Query: 103 PPARTSKGHCTNSPTT*RSGSIMKRTATSSCPVCRR 210
PP RTSK T +PTT R+ + + T T+ P RR
Sbjct: 338 PPPRTSKRPVTQAPTTPRATTTRRPTTTTPRPTPRR 373
>UniRef50_A0CDU9 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_17,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 98
Score = 32.3 bits (70), Expect = 6.9
Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +3
Query: 249 ETLQEIY-QVARLHPHKCFNNKIFKLLRDQKETAVGTLEKSSALFVDERMIVQEKFQVDV 425
+ L E Y +V +L H CF NKI DQK E + DE + Q K + D+
Sbjct: 3 DELAEFYKEVLKLISHLCFENKI---TEDQKS------ELKKLIMEDEEFVAQLKEEYDI 53
Query: 426 QKTGVCGVKVLSFDDTISSAA 488
+ G+ G++ + D++S+++
Sbjct: 54 E--GLNGLENIIVGDSVSNSS 72
>UniRef50_Q75DM1 Cluster: ABL004Wp; n=1; Eremothecium gossypii|Rep:
ABL004Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 319
Score = 32.3 bits (70), Expect = 6.9
Identities = 17/42 (40%), Positives = 21/42 (50%)
Frame = +1
Query: 100 KPPARTSKGHCTNSPTT*RSGSIMKRTATSSCPVCRRGLLYP 225
+P + +K C +P T RS M R CP CR GLL P
Sbjct: 174 EPENKRAKHACEGTPETLRSRLDMLRGDLPRCPRCRVGLLRP 215
>UniRef50_UPI00015B414F Cluster: PREDICTED: similar to serpin 3a;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
serpin 3a - Nasonia vitripennis
Length = 1026
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 2/115 (1%)
Frame = +3
Query: 180 SHFVMSGLSAWTLISALSFGATDETLQEIYQVARLHPH-KCFNNKIFKLLRD-QKETAVG 353
++ ++S +S + L GA DET Q++ V L +K +L+ Q
Sbjct: 259 ANLLVSPISLKLALVLLYEGAQDETAQQLATVMHLPVGILATRDKFSSVLKSLQTRRPEY 318
Query: 354 TLEKSSALFVDERMIVQEKFQVDVQKTGVCGVKVLSFDDTISSAATINQYVNEVT 518
L + +F+D+ + ++++ ++ + L+F +T SA IN Y +T
Sbjct: 319 ELNLGTRIFLDQSVTPRQRYGAILKTFYNTDIVSLNFSNTRPSAELINDYARNIT 373
>UniRef50_A4CNJ6 Cluster: Putative uncharacterized protein; n=1;
Robiginitalea biformata HTCC2501|Rep: Putative
uncharacterized protein - Robiginitalea biformata
HTCC2501
Length = 188
Score = 31.9 bits (69), Expect = 9.2
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Frame = -1
Query: 485 CRGDRIVKRQNFDPTNTSFLHVHLEFFLHDHPLVNEQS*AFLQRPDGSF---LLIPE 324
C G + + Q+ T T +H++ L D N++ A L+ DG+F +LIPE
Sbjct: 12 CLGAPVSRAQDLWTTETGIVHINASTPLEDIDATNDRVNAILRHGDGAFAVVMLIPE 68
>UniRef50_A0ZSH9 Cluster: Putative uncharacterized protein; n=1;
Shewanella hanedai|Rep: Putative uncharacterized protein
- Shewanella hanedai (Alteromonas hanedai)
Length = 392
Score = 31.9 bits (69), Expect = 9.2
Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Frame = +3
Query: 63 LLTPGIYGQCNLKTAGAYFKRSLYEFSNDLAVRINY--ETDSHFVMSGLSAWTLISALSF 236
L GI Q N + + YF +++Y F+ D V INY T L L+F
Sbjct: 292 LFFDGIDAQGNARNSNGYFVQAMYSFT-DTRVGINYGISTLDRNANDPLVNLKQSEKLTF 350
Query: 237 GATDETLQEIYQVARLHPHKCFNNK 311
GA + + VA + ++ NNK
Sbjct: 351 GAYHSLFEGLTLVAEVSMYESENNK 375
>UniRef50_Q59L91 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 261
Score = 31.9 bits (69), Expect = 9.2
Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
Frame = +3
Query: 234 FGATDETLQEIYQVAR---LHPHKCFNNKIFKLLRDQKET 344
+ +T+ E++QV R HP + N+KI K++RD +ET
Sbjct: 40 YSSTNHITNELFQVTRDKNRHPKRLNNDKIQKMIRDLEET 79
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 534,326,738
Number of Sequences: 1657284
Number of extensions: 10779995
Number of successful extensions: 30740
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 29789
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30727
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 32619212418
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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