Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS310H10f
(475 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B6370 Cluster: PREDICTED: similar to conserved ... 142 5e-33
UniRef50_Q9U4H5 Cluster: TM2 domain-containing protein almondex ... 142 5e-33
UniRef50_A7SRN2 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 128 6e-29
UniRef50_Q9BRN9 Cluster: TM2 domain-containing protein 3 precurs... 126 2e-28
UniRef50_Q95QZ5 Cluster: TM2 domain-containing protein C41D11.9 ... 111 6e-24
UniRef50_Q5DFA0 Cluster: SJCHGC08970 protein; n=1; Schistosoma j... 88 8e-17
UniRef50_A2FYD7 Cluster: TM2 domain containing protein; n=1; Tri... 63 3e-09
UniRef50_Q9W2H1 Cluster: TM2 domain-containing protein CG10795 p... 61 1e-08
UniRef50_UPI0000E480CC Cluster: PREDICTED: similar to TM2 domain... 60 3e-08
UniRef50_Q4RGB7 Cluster: Chromosome 12 SCAF15104, whole genome s... 58 1e-07
UniRef50_Q5BTF3 Cluster: SJCHGC01602 protein; n=2; Schistosoma j... 58 1e-07
UniRef50_Q29HU7 Cluster: GA10761-PA; n=3; Diptera|Rep: GA10761-P... 58 1e-07
UniRef50_A2DYP8 Cluster: TM2 domain containing protein; n=1; Tri... 58 1e-07
UniRef50_Q9VY86 Cluster: TM2 domain-containing protein CG11103 p... 58 1e-07
UniRef50_P61228 Cluster: TM2 domain-containing protein C02F5.13 ... 57 2e-07
UniRef50_Q95PJ8 Cluster: TM2 domain-containing protein Y66D12A.2... 56 3e-07
UniRef50_Q9BX73 Cluster: TM2 domain-containing protein 2 precurs... 55 7e-07
UniRef50_A7RXA9 Cluster: Predicted protein; n=1; Nematostella ve... 51 2e-05
UniRef50_Q9BX74 Cluster: TM2 domain-containing protein 1 precurs... 49 6e-05
UniRef50_Q2TBP3 Cluster: TM2 domain containing 3; n=2; Laurasiat... 48 8e-05
UniRef50_A2EDP9 Cluster: TM2 domain containing protein; n=1; Tri... 48 8e-05
UniRef50_A2DI05 Cluster: TM2 domain containing protein; n=1; Tri... 48 1e-04
UniRef50_A3JFM1 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_A2U1X3 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_A2DVK4 Cluster: TM2 domain containing protein; n=1; Tri... 45 7e-04
UniRef50_A4AFV7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q2I6M6 Cluster: TM2 transmembrane domain 2 protein; n=1... 43 0.004
UniRef50_A7AK86 Cluster: Putative uncharacterized protein; n=1; ... 43 0.004
UniRef50_A3J3L1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.004
UniRef50_Q7Q602 Cluster: ENSANGP00000030952; n=2; Culicidae|Rep:... 43 0.004
UniRef50_A1R8B7 Cluster: Putative TM2 domain family protein; n=1... 42 0.009
UniRef50_Q82HV7 Cluster: Putative uncharacterized protein; n=3; ... 41 0.016
UniRef50_Q03MK0 Cluster: Predicted membrane protein; n=3; Strept... 41 0.016
UniRef50_UPI00005847F7 Cluster: PREDICTED: similar to conserved ... 39 0.049
UniRef50_UPI000050FE16 Cluster: COG5651: PPE-repeat proteins; n=... 39 0.065
UniRef50_UPI000050FA70 Cluster: hypothetical protein BlinB010009... 38 0.11
UniRef50_A6PUA6 Cluster: TM2 domain containing protein+B7201; n=... 36 0.46
UniRef50_A2EP10 Cluster: TM2 domain containing protein; n=1; Tri... 36 0.46
UniRef50_A0J6E7 Cluster: TM2 domain containing protein+B7201; n=... 35 0.80
UniRef50_A2ADR2 Cluster: Beta-amyloid binding protein; n=1; Mus ... 35 1.1
UniRef50_Q11QQ0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.1
UniRef50_Q2JL13 Cluster: TM2 domain protein; n=2; Synechococcus|... 34 1.8
UniRef50_Q2JM68 Cluster: TM2 domain protein; n=2; Synechococcus|... 32 5.6
UniRef50_Q4SK02 Cluster: Chromosome 10 SCAF14571, whole genome s... 32 7.4
UniRef50_Q4Q7G0 Cluster: Putative uncharacterized protein; n=2; ... 32 7.4
UniRef50_UPI000051AD31 Cluster: PREDICTED: similar to limkain b1... 31 9.8
UniRef50_Q869U5 Cluster: Similar to Xanthomonas campestris (Pv. ... 31 9.8
>UniRef50_UPI00015B6370 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 452
Score = 142 bits (343), Expect = 5e-33
Identities = 59/96 (61%), Positives = 72/96 (75%)
Frame = -1
Query: 367 KYYLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQE 188
+YY +NCTV D++CLG+R+FLK + C+WT G +W ADRFYLGHWQE
Sbjct: 357 QYYRSNCTVKSDILCLGRRKFLKNLPCNWTGGYKWSTALILSITLGGFGADRFYLGHWQE 416
Query: 187 GIGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
GIGKLFSFGGLGVWTL+D +LI + +LGPADGSLYI
Sbjct: 417 GIGKLFSFGGLGVWTLIDVMLISMRYLGPADGSLYI 452
Score = 44.8 bits (101), Expect = 0.001
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = -2
Query: 471 NFXKSSMCRFCYQTDKWEHRCEQK 400
NF K+ +CR+CYQT+ WEH C QK
Sbjct: 323 NFVKTYICRYCYQTEAWEHNCYQK 346
>UniRef50_Q9U4H5 Cluster: TM2 domain-containing protein almondex
precursor; n=4; Endopterygota|Rep: TM2 domain-containing
protein almondex precursor - Drosophila melanogaster
(Fruit fly)
Length = 284
Score = 142 bits (343), Expect = 5e-33
Identities = 61/96 (63%), Positives = 70/96 (72%)
Frame = -1
Query: 367 KYYLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQE 188
K + TNCTV DV+CLG R F + +RC+WT G RW ADRFYLGHWQE
Sbjct: 189 KLFRTNCTVHHDVLCLGNRSFTRNLRCNWTQGYRWSTALLISLTLGGFGADRFYLGHWQE 248
Query: 187 GIGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
GIGKLFSFGGLGVWT++D LLI +H+LGPADGSLYI
Sbjct: 249 GIGKLFSFGGLGVWTIIDVLLISMHYLGPADGSLYI 284
Score = 35.1 bits (77), Expect = 0.80
Identities = 10/25 (40%), Positives = 17/25 (68%)
Frame = -2
Query: 474 KNFXKSSMCRFCYQTDKWEHRCEQK 400
++F + CR+CYQT+ W+ C Q+
Sbjct: 156 RSFQRQMNCRYCYQTEMWQQSCGQR 180
>UniRef50_A7SRN2 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 178
Score = 128 bits (309), Expect = 6e-29
Identities = 58/104 (55%), Positives = 72/104 (69%), Gaps = 10/104 (9%)
Frame = -1
Query: 361 YLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXA----------DR 212
Y+TNCTV ++V+CLG R F K +RC+WTSG RW + DR
Sbjct: 74 YITNCTVKEEVLCLGNRTFNKLLRCNWTSGYRWSTAVLLRLVDFNFFSLFLTLGGFGIDR 133
Query: 211 FYLGHWQEGIGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
FYLGHW+EG+GKLFSFGGLGVWTL+D +L+GI ++GPADGSLYI
Sbjct: 134 FYLGHWKEGLGKLFSFGGLGVWTLIDLVLVGIGYIGPADGSLYI 177
>UniRef50_Q9BRN9 Cluster: TM2 domain-containing protein 3 precursor;
n=31; Euteleostomi|Rep: TM2 domain-containing protein 3
precursor - Homo sapiens (Human)
Length = 247
Score = 126 bits (304), Expect = 2e-28
Identities = 55/94 (58%), Positives = 65/94 (69%)
Frame = -1
Query: 361 YLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGI 182
Y NCTV D V CLG R F K + C+WT G +W ADRFYLG W+EG+
Sbjct: 154 YPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGL 213
Query: 181 GKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
GKLFSFGGLG+WTL+D LLIG+ ++GPADGSLYI
Sbjct: 214 GKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 247
>UniRef50_Q95QZ5 Cluster: TM2 domain-containing protein C41D11.9
precursor; n=2; Caenorhabditis|Rep: TM2
domain-containing protein C41D11.9 precursor -
Caenorhabditis elegans
Length = 195
Score = 111 bits (268), Expect = 6e-24
Identities = 48/97 (49%), Positives = 63/97 (64%)
Frame = -1
Query: 370 SKYYLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQ 191
+K +T C+ VIC+G+R F K++ C+W+SG W ADRFYLG W+
Sbjct: 99 TKLLVTKCSAHSSVICMGQRNFYKRIPCNWSSGYSWTKTMILSVVLGGFGADRFYLGLWK 158
Query: 190 EGIGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
IGKLFSFGGLGVWTLVD +LI + ++ P DGS+YI
Sbjct: 159 SAIGKLFSFGGLGVWTLVDVVLIAVGYIKPYDGSMYI 195
>UniRef50_Q5DFA0 Cluster: SJCHGC08970 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08970 protein - Schistosoma
japonicum (Blood fluke)
Length = 274
Score = 88.2 bits (209), Expect = 8e-17
Identities = 39/94 (41%), Positives = 55/94 (58%)
Frame = -1
Query: 364 YYLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEG 185
+Y T C V+CLG+R F + V C W++G + DRFYLG W EG
Sbjct: 180 FYETKCEPFPHVLCLGRRVFRRMVPCEWSTGKSYALTVVLSLFFGGFGVDRFYLGMWIEG 239
Query: 184 IGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLY 83
+GKLFSFGGLG+W++VD +LI ++ P ++Y
Sbjct: 240 LGKLFSFGGLGLWSIVDFILIVSGYVKPPGDAVY 273
>UniRef50_A2FYD7 Cluster: TM2 domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: TM2 domain containing
protein - Trichomonas vaginalis G3
Length = 168
Score = 63.3 bits (147), Expect = 3e-09
Identities = 33/90 (36%), Positives = 45/90 (50%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKLF 170
C+V CLG R F ++ C T+G ADRFYLG+ G+ KL
Sbjct: 79 CSVVATSQCLGSRSFSSQLFCQTTTGYSHATAVAMSILFGGFGADRFYLGYTGFGVLKLA 138
Query: 169 SFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
+ GG G+W+L+D + I L P DGS Y+
Sbjct: 139 TLGGFGLWSLIDLICIFTRTLKPIDGSFYV 168
>UniRef50_Q9W2H1 Cluster: TM2 domain-containing protein CG10795
precursor; n=7; Endopterygota|Rep: TM2 domain-containing
protein CG10795 precursor - Drosophila melanogaster
(Fruit fly)
Length = 178
Score = 60.9 bits (141), Expect = 1e-08
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Frame = -1
Query: 349 CTVSDDVICL--GKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGK 176
C ++++ C G F ++V C WT+G DRFYLG+ G+ K
Sbjct: 62 CIAANEINCTETGNATFTREVPCKWTNGYHLDTTLLLSVFLGMFGVDRFYLGYPGIGLLK 121
Query: 175 LFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
+ GG+ + L+D +LI + +GPADGS Y+
Sbjct: 122 FCTLGGMFLGQLIDIVLIALQVVGPADGSAYV 153
>UniRef50_UPI0000E480CC Cluster: PREDICTED: similar to TM2 domain
containing 2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to TM2 domain containing 2 -
Strongylocentrotus purpuratus
Length = 200
Score = 59.7 bits (138), Expect = 3e-08
Identities = 32/88 (36%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLK-KVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
C V + C G R F+K + C G + DRF +GH +GKL
Sbjct: 109 CRVLPGIECHGNRTFIKDNIPCLKFEGQHFISTLIFSIFLGFFGVDRFCMGHVPTAVGKL 168
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGS 89
+ GGLGVW +VD +L+ L PADGS
Sbjct: 169 LTLGGLGVWWIVDIVLLVTGGLMPADGS 196
>UniRef50_Q4RGB7 Cluster: Chromosome 12 SCAF15104, whole genome
shotgun sequence; n=4; Coelomata|Rep: Chromosome 12
SCAF15104, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 227
Score = 58.0 bits (134), Expect = 1e-07
Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLK-KVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
C+ DD+ C G R F + +V C +G + DRF LGH +GKL
Sbjct: 134 CSALDDIECAGPREFPRGQVPCVKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 193
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGS 89
+ GGLG+W VD +L+ L P+D S
Sbjct: 194 LTLGGLGIWWFVDLILLITGGLMPSDSS 221
>UniRef50_Q5BTF3 Cluster: SJCHGC01602 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC01602 protein - Schistosoma
japonicum (Blood fluke)
Length = 100
Score = 58.0 bits (134), Expect = 1e-07
Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFL-KKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
C D++ C G R FL C G + DR LGH GIGKL
Sbjct: 7 CHALDNIECYGNRTFLLPDYPCLHFKGHYFVTTFIYSLLLGFLGVDRLCLGHIGTGIGKL 66
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
+ GG G+W +VD +L+ +L PADGS ++
Sbjct: 67 LTLGGAGIWWIVDIILLIRGNLSPADGSSWM 97
>UniRef50_Q29HU7 Cluster: GA10761-PA; n=3; Diptera|Rep: GA10761-PA -
Drosophila pseudoobscura (Fruit fly)
Length = 214
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLKK-VRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
CTV D+ C G R F ++ V C + + DRF LG +GKL
Sbjct: 121 CTVYSDIDCYGDRTFFREGVPCVRYTDHYFVTTLIYSMLLGFLGMDRFCLGQTGTAVGKL 180
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGS 89
+ GG+GVW ++D +L+ ++L P DGS
Sbjct: 181 LTMGGVGVWWIIDVILLITNNLKPEDGS 208
>UniRef50_A2DYP8 Cluster: TM2 domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: TM2 domain containing
protein - Trichomonas vaginalis G3
Length = 155
Score = 58.0 bits (134), Expect = 1e-07
Identities = 33/93 (35%), Positives = 44/93 (47%)
Frame = -1
Query: 361 YLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGI 182
++ NCTV D V C G R F + C G + DRFYLG+ G
Sbjct: 45 WIQNCTVYDTVECTGNRTFSRYQWCPNRKGKSYSLAVVLSCLGGLFGFDRFYLGYTSLGF 104
Query: 181 GKLFSFGGLGVWTLVDALLIGIHHLGPADGSLY 83
K F+FG V ++D +LI +L PADG+ Y
Sbjct: 105 IKFFTFGIFFVDYILDIILILTQYLQPADGNGY 137
>UniRef50_Q9VY86 Cluster: TM2 domain-containing protein CG11103
precursor; n=3; Eumetazoa|Rep: TM2 domain-containing
protein CG11103 precursor - Drosophila melanogaster
(Fruit fly)
Length = 224
Score = 57.6 bits (133), Expect = 1e-07
Identities = 31/88 (35%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLKK-VRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
CTV D+ C G R FL+ V C + + DRF LG +GKL
Sbjct: 131 CTVFADIECYGNRTFLRAGVPCVRYTDHYFVTTLIYSMLLGFLGMDRFCLGQTGTAVGKL 190
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGS 89
+ GG+GVW ++D +L+ ++L P DGS
Sbjct: 191 LTMGGVGVWWIIDVILLITNNLLPEDGS 218
>UniRef50_P61228 Cluster: TM2 domain-containing protein C02F5.13
precursor; n=2; Caenorhabditis|Rep: TM2
domain-containing protein C02F5.13 precursor -
Caenorhabditis elegans
Length = 210
Score = 56.8 bits (131), Expect = 2e-07
Identities = 30/87 (34%), Positives = 40/87 (45%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKLF 170
C V + C G R F K C +G + DRF LG+ +GKL
Sbjct: 118 CRVLPCIECHGPRTFTKSTPCIIYNGHYFLTTLLYSIFLGVVAVDRFCLGYSAMAVGKLM 177
Query: 169 SFGGLGVWTLVDALLIGIHHLGPADGS 89
+ GG G+W +VD L+ + LGPAD S
Sbjct: 178 TLGGFGIWWIVDIFLLVLGVLGPADDS 204
>UniRef50_Q95PJ8 Cluster: TM2 domain-containing protein Y66D12A.21
precursor; n=2; Caenorhabditis|Rep: TM2
domain-containing protein Y66D12A.21 precursor -
Caenorhabditis elegans
Length = 329
Score = 56.4 bits (130), Expect = 3e-07
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Frame = -1
Query: 349 CTVSDDVICLGKRRF-----LKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEG 185
C ++ + C+GK +F C + + + DR YLG++ G
Sbjct: 57 CETAEHIKCVGKDQFGIFNRTVPSACHYGAHVSYTTTVLLSIFLGFFGIDRIYLGYYALG 116
Query: 184 IGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLY 83
+ K+FS GGL V+ LVD +LI + LGPADG+ Y
Sbjct: 117 LIKMFSLGGLFVFWLVDIILISLQLLGPADGTAY 150
>UniRef50_Q9BX73 Cluster: TM2 domain-containing protein 2 precursor;
n=18; Coelomata|Rep: TM2 domain-containing protein 2
precursor - Homo sapiens (Human)
Length = 214
Score = 55.2 bits (127), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLKKVR-CSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
C D + C R FL++ + C +G + DRF LGH +GKL
Sbjct: 121 CHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKL 180
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGS 89
+ GGLG+W VD +L+ L P+DGS
Sbjct: 181 LTLGGLGIWWFVDLILLITGGLMPSDGS 208
>UniRef50_A7RXA9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 144
Score = 50.8 bits (116), Expect = 2e-05
Identities = 28/76 (36%), Positives = 38/76 (50%)
Frame = -1
Query: 307 FLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKLFSFGGLGVWTLVDAL 128
F +KV C T+G + DRFYLG+ G+ K + G ++ LVD L
Sbjct: 47 FKRKVPCRHTNGHSYENALLLSIFLGMFGIDRFYLGYPAIGLLKFCTLGFFFIFQLVDVL 106
Query: 127 LIGIHHLGPADGSLYI 80
LI +GPADGS Y+
Sbjct: 107 LIATQIVGPADGSDYV 122
>UniRef50_Q9BX74 Cluster: TM2 domain-containing protein 1 precursor;
n=23; Euteleostomi|Rep: TM2 domain-containing protein 1
precursor - Homo sapiens (Human)
Length = 207
Score = 48.8 bits (111), Expect = 6e-05
Identities = 26/76 (34%), Positives = 39/76 (51%)
Frame = -1
Query: 307 FLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKLFSFGGLGVWTLVDAL 128
F K + C +G + ADRFYLG+ G+ K + G G+ +L+D +
Sbjct: 107 FFKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGIGSLIDFI 166
Query: 127 LIGIHHLGPADGSLYI 80
LI + +GP+DGS YI
Sbjct: 167 LISMQIVGPSDGSSYI 182
>UniRef50_Q2TBP3 Cluster: TM2 domain containing 3; n=2;
Laurasiatheria|Rep: TM2 domain containing 3 - Bos taurus
(Bovine)
Length = 190
Score = 48.4 bits (110), Expect = 8e-05
Identities = 19/33 (57%), Positives = 22/33 (66%)
Frame = -1
Query: 361 YLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRW 263
Y TNCTV D V CLG R F K + C+WT G +W
Sbjct: 128 YPTNCTVRDHVHCLGNRTFPKMLYCNWTGGYKW 160
>UniRef50_A2EDP9 Cluster: TM2 domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: TM2 domain containing
protein - Trichomonas vaginalis G3
Length = 180
Score = 48.4 bits (110), Expect = 8e-05
Identities = 27/94 (28%), Positives = 45/94 (47%)
Frame = -1
Query: 361 YLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGI 182
Y ++C + C+G F +K+ C ++ ADRFYLG++ +
Sbjct: 87 YFSDCRPTQ--YCMGNSIFQRKIVCKAAEKSQ-KTAFLLSLFLGGFAADRFYLGYYISAV 143
Query: 181 GKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
K + GG G+ + D LI +LGPA+G L++
Sbjct: 144 FKCLTIGGFGIAYMFDLFLILFGYLGPANGKLFV 177
>UniRef50_A2DI05 Cluster: TM2 domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: TM2 domain containing
protein - Trichomonas vaginalis G3
Length = 153
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/96 (34%), Positives = 44/96 (45%)
Frame = -1
Query: 370 SKYYLTNCTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQ 191
S YY +CT V C G+ +KV C T G ADRFYLG+
Sbjct: 42 SGYYEYSCTPV--VECEGETTVKQKVLCYPTDGKSPAIALTLSVVLGFLGADRFYLGYPT 99
Query: 190 EGIGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLY 83
GI K+F+ G G+ +D LI + PA G++Y
Sbjct: 100 IGIFKMFTGGFFGLGWYIDIFLIALRIAKPAQGNVY 135
>UniRef50_A3JFM1 Cluster: Putative uncharacterized protein; n=1;
Marinobacter sp. ELB17|Rep: Putative uncharacterized
protein - Marinobacter sp. ELB17
Length = 105
Score = 45.6 bits (103), Expect = 6e-04
Identities = 17/28 (60%), Positives = 20/28 (71%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVD 134
DRFYLG W+ GI K +FGGLG+W D
Sbjct: 29 DRFYLGKWKSGIAKALTFGGLGLWWFFD 56
>UniRef50_A2U1X3 Cluster: Putative uncharacterized protein; n=1;
Polaribacter dokdonensis MED152|Rep: Putative
uncharacterized protein - Polaribacter dokdonensis
MED152
Length = 123
Score = 45.6 bits (103), Expect = 6e-04
Identities = 19/43 (44%), Positives = 28/43 (65%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLIGIHHLGPADGS 89
DRFYLG+ G+ KL + GG G+W ++D ++I L P +GS
Sbjct: 76 DRFYLGYTLLGVLKLITLGGFGIWYIIDLIMIITGDLQPKNGS 118
>UniRef50_A2DVK4 Cluster: TM2 domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: TM2 domain containing
protein - Trichomonas vaginalis G3
Length = 178
Score = 45.2 bits (102), Expect = 7e-04
Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFLKKVRCSWTSGTRWXXXXXXXXXXXXXXA-DRFYLGHWQEGIGKL 173
C + + C+G++ ++ K + G + DRFYLG++ G KL
Sbjct: 86 CHPLNGIYCIGEQYWINKTYPCYEPGEKSVVTAILFSFLLGIFGVDRFYLGYYFLGFLKL 145
Query: 172 FSFGGLGVWTLVDALLIGIHHLGPADGS 89
F+ GG +W ++D +L+ GP +G+
Sbjct: 146 FTLGGFTLWWVIDFILLSFGVWGPVNGN 173
>UniRef50_A4AFV7 Cluster: Putative uncharacterized protein; n=1;
marine actinobacterium PHSC20C1|Rep: Putative
uncharacterized protein - marine actinobacterium
PHSC20C1
Length = 383
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/31 (58%), Positives = 22/31 (70%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALL 125
DRFYLG GI KL +FGG G+W L+D +L
Sbjct: 94 DRFYLGKVGTGILKLITFGGAGIWVLIDLIL 124
>UniRef50_Q2I6M6 Cluster: TM2 transmembrane domain 2 protein; n=1;
uncultured delta proteobacterium DeepAnt-1F12|Rep: TM2
transmembrane domain 2 protein - uncultured delta
proteobacterium DeepAnt-1F12
Length = 131
Score = 42.7 bits (96), Expect = 0.004
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = -1
Query: 214 RFYLGHWQEGIGKLFSFGGLGVWTLVDALLIGIHHLGPADG 92
RFY GH G+ +L + GG G+W L+D ++I + + +DG
Sbjct: 86 RFYTGHIGIGVVQLLTLGGCGIWALIDLIVIAVGNYRDSDG 126
>UniRef50_A7AK86 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 112
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/32 (53%), Positives = 23/32 (71%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
DRF +G W +GI KL + GGLG+W ++D LI
Sbjct: 62 DRFLIGDWGKGIIKLLTGGGLGIWYIIDWFLI 93
>UniRef50_A3J3L1 Cluster: Putative uncharacterized protein; n=1;
Flavobacteria bacterium BAL38|Rep: Putative
uncharacterized protein - Flavobacteria bacterium BAL38
Length = 113
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/32 (56%), Positives = 23/32 (71%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
DRFY+G G+GKL + GG+ VWT+VD LI
Sbjct: 64 DRFYIGDTGMGVGKLLTCGGIYVWTIVDWFLI 95
>UniRef50_Q7Q602 Cluster: ENSANGP00000030952; n=2; Culicidae|Rep:
ENSANGP00000030952 - Anopheles gambiae str. PEST
Length = 154
Score = 42.7 bits (96), Expect = 0.004
Identities = 13/21 (61%), Positives = 19/21 (90%)
Frame = -2
Query: 462 KSSMCRFCYQTDKWEHRCEQK 400
++ +CR+CYQT++WEH CEQK
Sbjct: 110 RTMVCRYCYQTERWEHGCEQK 130
>UniRef50_A1R8B7 Cluster: Putative TM2 domain family protein; n=1;
Arthrobacter aurescens TC1|Rep: Putative TM2 domain
family protein - Arthrobacter aurescens (strain TC1)
Length = 315
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALL 125
DRFYLG GI KL + GG G+W++VD ++
Sbjct: 76 DRFYLGKIGTGIAKLLTAGGFGIWSIVDLII 106
>UniRef50_Q82HV7 Cluster: Putative uncharacterized protein; n=3;
Actinomycetales|Rep: Putative uncharacterized protein -
Streptomyces avermitilis
Length = 166
Score = 40.7 bits (91), Expect = 0.016
Identities = 15/31 (48%), Positives = 23/31 (74%)
Frame = -1
Query: 214 RFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
RFY+G GI +LF+ GGLG+W L+D +++
Sbjct: 120 RFYMGSVGIGIAQLFTCGGLGIWALIDGVML 150
>UniRef50_Q03MK0 Cluster: Predicted membrane protein; n=3;
Streptococcus thermophilus|Rep: Predicted membrane
protein - Streptococcus thermophilus (strain ATCC
BAA-491 / LMD-9)
Length = 110
Score = 40.7 bits (91), Expect = 0.016
Identities = 18/32 (56%), Positives = 22/32 (68%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
DRF LG GIGKL + GG G+W++VD LI
Sbjct: 62 DRFMLGQVGLGIGKLLTCGGCGIWSIVDWFLI 93
>UniRef50_UPI00005847F7 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to conserved
hypothetical protein - Strongylocentrotus purpuratus
Length = 195
Score = 39.1 bits (87), Expect = 0.049
Identities = 25/75 (33%), Positives = 33/75 (44%)
Frame = -1
Query: 307 FLKKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKLFSFGGLGVWTLVDAL 128
+ K+V C T G + DR YLG+ G+ K + G L V VD +
Sbjct: 94 YQKQVPCRNTKGYSYRTTLLLSIFLGMFGVDRMYLGYPALGLLKFCTMGLLFVGHFVDVI 153
Query: 127 LIGIHHLGPADGSLY 83
LI +GPAD S Y
Sbjct: 154 LIATQVVGPADRSEY 168
>UniRef50_UPI000050FE16 Cluster: COG5651: PPE-repeat proteins; n=1;
Brevibacterium linens BL2|Rep: COG5651: PPE-repeat
proteins - Brevibacterium linens BL2
Length = 337
Score = 38.7 bits (86), Expect = 0.065
Identities = 16/32 (50%), Positives = 21/32 (65%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
DRFYLG GI KL + G G+W LVD +++
Sbjct: 35 DRFYLGKVGTGILKLLTLAGFGIWWLVDVVVV 66
>UniRef50_UPI000050FA70 Cluster: hypothetical protein BlinB01000941;
n=1; Brevibacterium linens BL2|Rep: hypothetical protein
BlinB01000941 - Brevibacterium linens BL2
Length = 146
Score = 37.9 bits (84), Expect = 0.11
Identities = 15/32 (46%), Positives = 22/32 (68%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
DRFY G + G KL S GGLG+W ++D +++
Sbjct: 65 DRFYTGRFLTGGLKLVSLGGLGLWWVIDLVIV 96
>UniRef50_A6PUA6 Cluster: TM2 domain containing protein+B7201; n=1;
Victivallis vadensis ATCC BAA-548|Rep: TM2 domain
containing protein+B7201 - Victivallis vadensis ATCC
BAA-548
Length = 103
Score = 35.9 bits (79), Expect = 0.46
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVD 134
DR YLG GI K+ + GGLG+W L+D
Sbjct: 49 DRIYLGQIGLGILKILTTGGLGIWWLID 76
>UniRef50_A2EP10 Cluster: TM2 domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: TM2 domain containing
protein - Trichomonas vaginalis G3
Length = 184
Score = 35.9 bits (79), Expect = 0.46
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = -1
Query: 349 CTVSDDVICLGKRRFL-KKVRCSWTSGTRWXXXXXXXXXXXXXXADRFYLGHWQEGIGKL 173
C ++ + CLG + ++ + RC + DRF LG+ G+ KL
Sbjct: 92 CQPAEGIECLGDKYWIVQDARCFVDGEKSYITLLLCSIFFGIFGVDRFLLGNPVLGVVKL 151
Query: 172 FSFGGLGVWTLVDALLIGIHHLGP 101
+ GG ++ VD +LI + L P
Sbjct: 152 CTLGGFFIFYFVDIILISLGKLQP 175
>UniRef50_A0J6E7 Cluster: TM2 domain containing protein+B7201; n=1;
Shewanella woodyi ATCC 51908|Rep: TM2 domain containing
protein+B7201 - Shewanella woodyi ATCC 51908
Length = 101
Score = 35.1 bits (77), Expect = 0.80
Identities = 15/32 (46%), Positives = 19/32 (59%)
Frame = -1
Query: 217 DRFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
DRFYLG GI K + GGLG+W D ++
Sbjct: 25 DRFYLGFIGLGILKAITLGGLGIWWFFDGAVL 56
>UniRef50_A2ADR2 Cluster: Beta-amyloid binding protein; n=1; Mus
musculus|Rep: Beta-amyloid binding protein - Mus
musculus (Mouse)
Length = 139
Score = 34.7 bits (76), Expect = 1.1
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = -1
Query: 187 GIGKLFSFGGLGVWTLVDALLIGIHHLGPADGSLYI 80
G+ K + G G+ +L+D +LI + +GP+DGS YI
Sbjct: 79 GLLKFCTVGFCGIGSLIDFILISMQIVGPSDGSSYI 114
>UniRef50_Q11QQ0 Cluster: Putative uncharacterized protein; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Putative
uncharacterized protein - Cytophaga hutchinsonii (strain
ATCC 33406 / NCIMB 9469)
Length = 88
Score = 34.7 bits (76), Expect = 1.1
Identities = 15/41 (36%), Positives = 26/41 (63%)
Frame = -1
Query: 214 RFYLGHWQEGIGKLFSFGGLGVWTLVDALLIGIHHLGPADG 92
RF +G+ + I + + GGLG+W+L D + I ++ + ADG
Sbjct: 45 RFMMGY-KTWILQFITLGGLGIWSLYDLVKIALNEMSMADG 84
>UniRef50_Q2JL13 Cluster: TM2 domain protein; n=2;
Synechococcus|Rep: TM2 domain protein - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 1569
Score = 33.9 bits (74), Expect = 1.8
Identities = 15/31 (48%), Positives = 20/31 (64%)
Frame = -1
Query: 214 RFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
RFYLG W G+ L +FG LG+ L+D + I
Sbjct: 107 RFYLGRWGTGLLWLLTFGLLGIGQLLDLIWI 137
>UniRef50_Q2JM68 Cluster: TM2 domain protein; n=2;
Synechococcus|Rep: TM2 domain protein - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 177
Score = 32.3 bits (70), Expect = 5.6
Identities = 17/31 (54%), Positives = 19/31 (61%)
Frame = -1
Query: 214 RFYLGHWQEGIGKLFSFGGLGVWTLVDALLI 122
RFYLG GI LF+FG LG L+D LI
Sbjct: 34 RFYLGKTGTGILWLFTFGLLGFGQLIDLFLI 64
>UniRef50_Q4SK02 Cluster: Chromosome 10 SCAF14571, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF14571, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 551
Score = 31.9 bits (69), Expect = 7.4
Identities = 18/66 (27%), Positives = 26/66 (39%)
Frame = +3
Query: 93 PSAGPKWCIPINNASTRVHTPRPPKLKSLPMPSCQXXXXXXXXXXXXXVNARTSAVPQRV 272
PS C P +++S ++ TPRP + +LP P T P R+
Sbjct: 175 PSDAVAVCSPSSSSSVKIPTPRPHESPTLPPPHLPTLHPPVGVPSGSPPMVMTPRGPMRL 234
Query: 273 PDVQEH 290
P EH
Sbjct: 235 PLFMEH 240
>UniRef50_Q4Q7G0 Cluster: Putative uncharacterized protein; n=2;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 1471
Score = 31.9 bits (69), Expect = 7.4
Identities = 12/32 (37%), Positives = 15/32 (46%)
Frame = -3
Query: 224 WS*PLLSWSLARRHW*TF*FWWPWSVDPSGCI 129
W PL SW L HW T +W DP+ +
Sbjct: 569 WPSPLSSWKLRSTHWKTLSSFWATKADPASSL 600
>UniRef50_UPI000051AD31 Cluster: PREDICTED: similar to limkain b1;
n=1; Apis mellifera|Rep: PREDICTED: similar to limkain
b1 - Apis mellifera
Length = 609
Score = 31.5 bits (68), Expect = 9.8
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +1
Query: 178 YQCLLANDQDKSGQLQNLLKLMPEQVLYPNESLMSRSILLS*GTASSPNIXHHQIQC 348
Y L ANDQD+ G + L++ Q L S + SI + T+ SP + H++ C
Sbjct: 9 YYALCANDQDELGLNEKLIENSISQSLCDLNS-SNNSITVENATSVSPLLSHYKYHC 64
>UniRef50_Q869U5 Cluster: Similar to Xanthomonas campestris (Pv.
campestris). Tetracycline- efflux transporter; n=2;
Dictyostelium discoideum|Rep: Similar to Xanthomonas
campestris (Pv. campestris). Tetracycline- efflux
transporter - Dictyostelium discoideum (Slime mold)
Length = 473
Score = 31.5 bits (68), Expect = 9.8
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Frame = -1
Query: 175 LFSFGG--LGVWTLVDALL-IGIHHLGPADGSLYI*LDLI*CCYINVIFLNKSLSIVKK 8
L+SF G LG+ ++ L+ + I LG LY+ L+ C+I + FL +SL I K+
Sbjct: 172 LYSFAGASLGIGVVIGPLIFVFISSLGSQFIPLYVTGGLMSLCFIGIPFLPESLEIAKE 230
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 407,908,188
Number of Sequences: 1657284
Number of extensions: 7424960
Number of successful extensions: 17250
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 16848
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17241
length of database: 575,637,011
effective HSP length: 94
effective length of database: 419,852,315
effective search space used: 26450695845
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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