Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS308H11f
(521 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 223 1e-57
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 218 7e-56
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 205 5e-52
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 194 8e-49
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 177 1e-43
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 176 3e-43
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 175 5e-43
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 167 1e-40
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 167 2e-40
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 166 2e-40
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 166 3e-40
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 165 4e-40
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 165 5e-40
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 165 7e-40
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 165 7e-40
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 164 1e-39
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 164 1e-39
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 164 1e-39
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 164 1e-39
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 162 5e-39
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 160 2e-38
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 160 2e-38
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 159 3e-38
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 157 1e-37
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 157 2e-37
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 155 6e-37
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 155 6e-37
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 153 2e-36
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 151 7e-36
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 151 1e-35
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 150 2e-35
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 149 3e-35
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 149 5e-35
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 148 9e-35
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 147 2e-34
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 146 2e-34
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 146 4e-34
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 142 3e-33
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 142 6e-33
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 141 8e-33
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 140 2e-32
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 138 9e-32
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 138 9e-32
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 137 1e-31
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 136 4e-31
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 135 5e-31
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 135 7e-31
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 134 9e-31
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 134 9e-31
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 133 2e-30
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 132 4e-30
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 132 4e-30
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 132 4e-30
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 132 4e-30
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 132 5e-30
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 130 2e-29
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 129 3e-29
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 128 8e-29
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 128 1e-28
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 127 1e-28
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 126 2e-28
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 126 3e-28
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 126 4e-28
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 125 7e-28
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 124 9e-28
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 124 9e-28
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 124 9e-28
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 124 2e-27
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 123 2e-27
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 123 2e-27
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 122 4e-27
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 121 1e-26
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 120 2e-26
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 120 2e-26
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 119 5e-26
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 119 5e-26
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 118 6e-26
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 118 8e-26
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 118 8e-26
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 118 1e-25
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 118 1e-25
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 118 1e-25
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 117 1e-25
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 117 1e-25
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 116 2e-25
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 116 2e-25
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 116 3e-25
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 115 6e-25
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 115 6e-25
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 115 8e-25
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 114 1e-24
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 113 2e-24
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 113 2e-24
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 113 3e-24
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 112 4e-24
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 111 7e-24
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 7e-24
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 111 9e-24
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 1e-23
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 110 2e-23
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 110 2e-23
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 110 2e-23
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 110 2e-23
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 3e-23
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 3e-23
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 109 4e-23
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 4e-23
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 5e-23
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 108 7e-23
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 108 7e-23
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 108 7e-23
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 108 9e-23
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 107 1e-22
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 1e-22
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 2e-22
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 2e-22
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 107 2e-22
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 107 2e-22
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 2e-22
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 2e-22
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 106 3e-22
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 106 3e-22
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 106 3e-22
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 106 4e-22
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 5e-22
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 105 5e-22
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 5e-22
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 105 5e-22
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 105 6e-22
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 105 6e-22
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 8e-22
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 105 8e-22
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 104 1e-21
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 104 1e-21
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 103 2e-21
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 2e-21
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 2e-21
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 2e-21
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 2e-21
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 2e-21
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 103 2e-21
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 103 2e-21
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 103 3e-21
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 103 3e-21
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 103 3e-21
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 102 4e-21
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 102 4e-21
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 102 6e-21
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 102 6e-21
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 101 8e-21
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 101 1e-20
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 101 1e-20
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 101 1e-20
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 101 1e-20
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 101 1e-20
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 100 2e-20
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 100 2e-20
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 100 2e-20
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 100 2e-20
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 100 2e-20
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 100 2e-20
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 100 2e-20
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 100 2e-20
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 99 3e-20
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 3e-20
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 99 3e-20
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 100 4e-20
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 100 4e-20
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 100 4e-20
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 100 4e-20
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 5e-20
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 5e-20
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 99 7e-20
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 7e-20
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 7e-20
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 7e-20
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 99 7e-20
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 98 9e-20
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 9e-20
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 98 9e-20
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 98 1e-19
UniRef50_Q9K1Q1 Cluster: Glycerate dehydrogenase; n=6; cellular ... 98 1e-19
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 98 1e-19
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 97 2e-19
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 97 2e-19
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 97 2e-19
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 97 2e-19
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 97 2e-19
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 2e-19
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 2e-19
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 97 2e-19
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 97 2e-19
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 2e-19
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 97 3e-19
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 3e-19
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 97 3e-19
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 3e-19
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 96 4e-19
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 96 4e-19
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 96 5e-19
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 96 5e-19
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 96 5e-19
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 95 7e-19
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 95 7e-19
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 95 7e-19
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 7e-19
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 7e-19
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 95 7e-19
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 95 7e-19
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 95 9e-19
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 95 9e-19
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 95 9e-19
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 95 9e-19
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 95 9e-19
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 95 1e-18
UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4; Gamma... 95 1e-18
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 1e-18
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 95 1e-18
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 95 1e-18
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 95 1e-18
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 94 2e-18
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 94 2e-18
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 94 2e-18
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 94 2e-18
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 93 3e-18
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 93 3e-18
UniRef50_Q82W00 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 4e-18
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 93 4e-18
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 4e-18
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 93 4e-18
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 4e-18
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 93 5e-18
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 93 5e-18
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 5e-18
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 5e-18
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 93 5e-18
UniRef50_Q22CX9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 5e-18
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 93 5e-18
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 92 6e-18
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 92 6e-18
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 92 6e-18
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 92 6e-18
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 92 8e-18
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 92 8e-18
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 92 8e-18
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 92 8e-18
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 92 8e-18
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 92 8e-18
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 91 1e-17
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 91 1e-17
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 1e-17
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 91 1e-17
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 1e-17
UniRef50_Q54UF7 Cluster: Putative uncharacterized protein; n=1; ... 91 1e-17
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 91 1e-17
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 91 1e-17
UniRef50_A0AFI6 Cluster: Complete genome; n=1; Listeria welshime... 91 1e-17
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 91 2e-17
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 91 2e-17
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 91 2e-17
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 91 2e-17
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 90 2e-17
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 90 2e-17
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 90 2e-17
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 2e-17
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 90 3e-17
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 90 3e-17
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 90 3e-17
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 3e-17
UniRef50_P30799 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 90 3e-17
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 89 4e-17
UniRef50_Q87JV4 Cluster: D-lactate dehydrogenase; n=6; Vibrio|Re... 89 4e-17
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 89 4e-17
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 89 4e-17
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 4e-17
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 89 6e-17
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 89 6e-17
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 8e-17
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 8e-17
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 89 8e-17
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 89 8e-17
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 1e-16
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 88 1e-16
UniRef50_A3XKE7 Cluster: D-lactate dehydrogenase; n=3; Bacteria|... 88 1e-16
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 88 1e-16
UniRef50_Q7Z019 Cluster: Putative D-lactate dehydrogenase; n=1; ... 88 1e-16
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 88 1e-16
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 88 1e-16
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 88 1e-16
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 88 1e-16
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 1e-16
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 88 1e-16
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 88 1e-16
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 2e-16
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 2e-16
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 2e-16
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 87 2e-16
UniRef50_Q97IU7 Cluster: Lactate dehydrogenase; n=5; Clostridial... 87 3e-16
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 87 3e-16
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 87 3e-16
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 87 3e-16
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 86 4e-16
UniRef50_O24922 Cluster: Phosphoglycerate dehydrogenase; n=4; He... 86 4e-16
UniRef50_A5TUT7 Cluster: Dehydrogenase; n=4; Fusobacterium nucle... 86 4e-16
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 4e-16
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 86 4e-16
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 86 5e-16
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 86 5e-16
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 86 5e-16
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 5e-16
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 5e-16
UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10; Bacteria... 86 5e-16
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 5e-16
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 86 5e-16
UniRef50_A2R1X3 Cluster: Remark: D(--)-Mandelate dehydrogenase; ... 86 5e-16
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 85 7e-16
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 85 7e-16
UniRef50_UPI000023E18D Cluster: hypothetical protein FG04024.1; ... 85 9e-16
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 85 9e-16
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 9e-16
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 85 9e-16
UniRef50_A6VXE9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 9e-16
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 85 9e-16
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 85 9e-16
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 85 9e-16
UniRef50_Q8UBA7 Cluster: 2-hydroxyacid-family dehydrogenase; n=5... 85 1e-15
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 85 1e-15
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 85 1e-15
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 85 1e-15
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15
UniRef50_P53839 Cluster: Putative 2-hydroxyacid dehydrogenase YN... 85 1e-15
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 84 2e-15
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_Q5LSR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 84 2e-15
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 84 2e-15
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 84 2e-15
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 83 3e-15
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 83 3e-15
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 83 3e-15
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 3e-15
UniRef50_Q1FLB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 3e-15
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 3e-15
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 83 3e-15
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 83 3e-15
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 83 3e-15
UniRef50_P45250 Cluster: Putative 2-hydroxyacid dehydrogenase HI... 83 3e-15
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 83 4e-15
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 83 4e-15
UniRef50_Q3IFC5 Cluster: 2-hydroxyacid dehydrogenase family prot... 83 4e-15
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 4e-15
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 83 4e-15
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 83 4e-15
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 83 4e-15
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 83 5e-15
UniRef50_A1RBK7 Cluster: Putative 2-hydroxyacid-family dehydroge... 83 5e-15
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 83 5e-15
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 82 7e-15
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 82 7e-15
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 82 7e-15
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 82 7e-15
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 82 7e-15
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 82 7e-15
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 82 9e-15
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 82 9e-15
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 82 9e-15
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 81 1e-14
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 81 1e-14
UniRef50_Q8RC97 Cluster: Phosphoglycerate dehydrogenase and rela... 81 2e-14
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 81 2e-14
UniRef50_Q2CCV7 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_A5BY55 Cluster: Putative uncharacterized protein; n=2; ... 81 2e-14
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 81 2e-14
UniRef50_Q0V2B9 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc... 81 2e-14
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 81 2e-14
UniRef50_Q4ZUB9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_Q1E2M0 Cluster: Putative uncharacterized protein; n=3; ... 81 2e-14
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 80 3e-14
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 3e-14
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 80 3e-14
UniRef50_A6Q6K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 3e-14
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 80 3e-14
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 80 3e-14
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 80 3e-14
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 80 3e-14
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 80 3e-14
UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;... 80 3e-14
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 80 3e-14
UniRef50_Q8GR83 Cluster: Hypothetical dehydrogenase protein; n=3... 80 3e-14
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 5e-14
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 79 5e-14
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 5e-14
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 79 5e-14
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 5e-14
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 79 5e-14
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 79 6e-14
UniRef50_Q0FUK3 Cluster: Predicted dehydrogenase; n=3; Rhodobact... 79 6e-14
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 79 6e-14
UniRef50_Q2AHD3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 8e-14
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 8e-14
UniRef50_Q11SX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 8e-14
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 79 8e-14
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 78 1e-13
UniRef50_A4AK07 Cluster: Glycerate dehydrogenase; n=1; marine ac... 78 1e-13
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 1e-13
UniRef50_A5V093 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 1e-13
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 1e-13
UniRef50_Q47748 Cluster: D-specific alpha-keto acid dehydrogenas... 78 1e-13
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 2e-13
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 77 2e-13
UniRef50_P33160 Cluster: Formate dehydrogenase; n=54; cellular o... 77 2e-13
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 2e-13
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 2e-13
UniRef50_Q1M7M0 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 77 2e-13
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 2e-13
UniRef50_Q0S7S0 Cluster: Probable phosphoglycerate dehydrogenase... 77 2e-13
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 77 3e-13
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 77 3e-13
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 76 4e-13
UniRef50_Q1ASE8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 6e-13
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 6e-13
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 76 6e-13
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 8e-13
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 75 8e-13
UniRef50_Q11GX7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 8e-13
UniRef50_A5G073 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 8e-13
UniRef50_Q5HL54 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_Q397D5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 75 1e-12
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5; ... 75 1e-12
UniRef50_UPI000038E31A Cluster: hypothetical protein Faci_030017... 75 1e-12
UniRef50_Q03UK9 Cluster: Lactate dehydrogenase; n=3; Leuconostoc... 75 1e-12
UniRef50_A5TSY9 Cluster: Possible dehydrogenase; n=1; Fusobacter... 75 1e-12
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_A1HMH1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 75 1e-12
UniRef50_Q9RJW2 Cluster: Possible 2-hydroxyacid-family dehydroge... 74 2e-12
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 74 2e-12
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 74 2e-12
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 74 2e-12
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 74 2e-12
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 74 2e-12
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 74 2e-12
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ... 74 2e-12
UniRef50_Q3M599 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_A7CUT0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 73 3e-12
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 3e-12
UniRef50_Q0HS14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 3e-12
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ... 73 3e-12
UniRef50_A1RMU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 3e-12
UniRef50_A1CFW0 Cluster: D-mandelate dehydrogenase, putative; n=... 73 3e-12
UniRef50_UPI00015B4E01 Cluster: PREDICTED: hypothetical protein;... 73 4e-12
UniRef50_Q9RJA1 Cluster: Putative 2-hydroxyacid-family dehydroge... 73 4e-12
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 73 4e-12
UniRef50_Q67M77 Cluster: Phosphoglycerate dehydrogenase, C-termi... 73 4e-12
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 4e-12
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 4e-12
UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 4e-12
UniRef50_A6GPV1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 4e-12
UniRef50_A5KMM3 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v... 73 4e-12
UniRef50_Q6L001 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 73 4e-12
UniRef50_Q9Z569 Cluster: Putative dehydrogenase; n=4; Actinomyce... 73 5e-12
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 5e-12
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 5e-12
UniRef50_Q97FN7 Cluster: D-lactate dehydrogenase; n=1; Clostridi... 72 7e-12
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 72 7e-12
UniRef50_Q1DT79 Cluster: Putative uncharacterized protein; n=1; ... 72 7e-12
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 72 9e-12
UniRef50_A0NJK9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 72 9e-12
UniRef50_A0JVT0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 9e-12
UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 72 9e-12
UniRef50_Q9A6E7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 1e-11
UniRef50_Q8ES01 Cluster: Dehydrogenase; n=4; Bacillaceae|Rep: De... 71 1e-11
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 1e-11
UniRef50_Q047V3 Cluster: Lactate dehydrogenase related 2-hydroxy... 71 2e-11
UniRef50_Q01QI5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_A3PUV5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 223 bits (546), Expect = 1e-57
Identities = 100/172 (58%), Positives = 131/172 (76%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A +KGV V+N PG N++SACELTC L+ LAR+V A +LK GRWDR LY+G
Sbjct: 80 DNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNVTQAVQSLKDGRWDRKLYSG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL+GKTLA+LG+GR+GREV RM A+GM +I FDP ++++ + K L++IWP+A
Sbjct: 140 FELSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDPLLTSEDANYLNVEKFSLDEIWPMA 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
DYIT+HTPLI T+N INA L +CKKGV+IINV RGG++ E L ALKSG
Sbjct: 200 DYITVHTPLIPQTKNLINATTLAKCKKGVRIINVARGGIVDEEALLNALKSG 251
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 218 bits (532), Expect = 7e-56
Identities = 98/172 (56%), Positives = 126/172 (73%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A + G+ V+N PG N++SACELTC ++ LAR+VV A ++K GRWDR LY G
Sbjct: 80 DNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNVVQAGQSMKEGRWDRKLYAG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL+GK L ++G GR+GREVA RM AFGM II +DPF + +Q AQ TK ELEDIW A
Sbjct: 140 RELSGKALGVVGFGRIGREVAHRMKAFGMEIIAYDPFFTKEQAAQIGVTKGELEDIWKNA 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
DYIT+HTPLI T+N INA L +CKKGV I+NV RGG++ E L ++ +G
Sbjct: 200 DYITVHTPLIPQTKNLINATTLAKCKKGVYIVNVARGGIVDEEALLHSINAG 251
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 205 bits (500), Expect = 5e-52
Identities = 88/173 (50%), Positives = 128/173 (73%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR + A+ ++K G+W+R + G
Sbjct: 81 DNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMG 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL GKTL ILGLGR+GREVATRM +FGM IG+DP +S + A F ++ LE+IWPL
Sbjct: 141 TELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLC 200
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+IT+HTPL+ ST +N + QCKKGV+++N RGG++ E L+AL+SG+
Sbjct: 201 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQ 253
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 194 bits (474), Expect = 8e-49
Identities = 92/172 (53%), Positives = 117/172 (68%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID +A GV V+N PG N LSA E TC L+ LARH+ AS + K G+W+R + G
Sbjct: 81 DNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQASASTKEGKWERKQFMG 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL GKTLAI+GLGR+GREVA RM ++G+ IG+DP VS A+ + ME E IWPLA
Sbjct: 141 NELFGKTLAIIGLGRIGREVALRMQSYGVKTIGYDPLVSPQDAAESNIEWMETEKIWPLA 200
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
DYIT+H PLI T+ +N + CKKGV I+NV RGG+I E L+ L+SG
Sbjct: 201 DYITVHVPLIPPTKGMLNDKTIGMCKKGVYILNVARGGIIDEEALLRGLESG 252
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 177 bits (431), Expect = 1e-43
Identities = 84/171 (49%), Positives = 109/171 (63%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 186
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 187 LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADY 366
L GKTL I+GLGR+GREVA RM +FGM IGFDP V A++ Q++ LE +WP DY
Sbjct: 106 LYGKTLGIVGLGRIGREVAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLEQMWPRCDY 165
Query: 367 ITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
IT+HTPLI T+ + K CK GVK++NV RGG+I E ++AL +G+
Sbjct: 166 ITVHTPLIPQTKGLLGDASFKLCKPGVKVVNVARGGIIDEEGLVRALDAGQ 216
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 176 bits (428), Expect = 3e-43
Identities = 82/173 (47%), Positives = 120/173 (69%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A + AG+W+R + G
Sbjct: 77 DNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHKSAAAGKWEREKFKG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL KTL I+G G++G EVA R AFGM ++G+DP+++ ++ A+ K L++I A
Sbjct: 137 VELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPYLTEERAAKLGIKKATLDEIAAQA 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+ITLHTPL++ T++ IN L + KKGV+IIN RGGL+ E LQAL+ G+
Sbjct: 197 DFITLHTPLMKETKHLINEAFLAKTKKGVRIINCARGGLVDEQALLQALQEGR 249
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 175 bits (426), Expect = 5e-43
Identities = 76/173 (43%), Positives = 121/173 (69%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +LK+G+W+R+ + G
Sbjct: 76 DNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSGKWERSKFMG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ KTL I+GLGR+G E+ R +FGM ++ +DPF +A++ Q L++I+ A
Sbjct: 136 VEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPFTTAERAQQIGARLTTLDEIYEKA 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+IT+HTPL ST++ ++ ++ KKGV+IIN RGG+I E L+A+KSGK
Sbjct: 196 DFITVHTPLTPSTKHMVSTAQFEKMKKGVRIINCARGGIIDEAALLEAIKSGK 248
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 167 bits (406), Expect = 1e-40
Identities = 75/172 (43%), Positives = 118/172 (68%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A ++G+ V+NAP +N+++ ELT L+L LARH+ A +++ AG+W+R + G
Sbjct: 75 DNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWERNRFMG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ KTL ++GLGR+G EVA R M+++ +DP VS ++ AQ T LE++ A
Sbjct: 135 FEVRNKTLGLVGLGRIGAEVARRARGLEMHVVAYDPVVSTERAAQLGATLAPLEEVLAQA 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH PLI++TRN I+A L Q K+G +IN RGG++ E L+A++SG
Sbjct: 195 DIVSLHVPLIDATRNMIDAARLAQMKRGAYLINAARGGVVDEAALLEAIESG 246
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 167 bits (405), Expect = 2e-40
Identities = 75/172 (43%), Positives = 113/172 (65%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+ +A ++G+ V+N P N+++ E LM +AR + A T+ +AG+W++ + G
Sbjct: 84 DNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADTSTRAGKWEKNRFMG 143
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ GKTL ++G G +G VATR M+++ FDPF+S + + K+EL+++ A
Sbjct: 144 VEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPFLSDARAQELGVEKVELDELLARA 203
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+ITLHTPLI+ TRN INA L + K GV+I+N RGGLI E D + ALKSG
Sbjct: 204 DFITLHTPLIDKTRNIINAQTLAKMKPGVRIVNCARGGLIVEKDLIAALKSG 255
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 166 bits (404), Expect = 2e-40
Identities = 77/172 (44%), Positives = 111/172 (64%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+D A K GV VINAP N +S E T ++ L RH+ A+ ++K+ W+R Y G
Sbjct: 74 DNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVG 133
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
SEL GKTL I+GLGR+G E+A R AFGM + FDPF++ ++ + E++ A
Sbjct: 134 SELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESA 193
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D IT+HTPL + T+ +N + + + KKGV++IN RGG+I E L+AL++G
Sbjct: 194 DIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENG 245
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 166 bits (403), Expect = 3e-40
Identities = 77/174 (44%), Positives = 116/174 (66%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID +A ++G+ V+N P N S E T LM+ LAR++ PA +K G+W+R TG
Sbjct: 77 DNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYATMKEGKWERKKLTG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC-TKMELEDIWPL 357
+++AGKTLAI+GLGR+G VA R M +IG+DPF+SA++ A++ E++++
Sbjct: 137 TQVAGKTLAIIGLGRIGLSVAHRAQGLEMKVIGYDPFMSAERAAEYGIELYKEVDELVKH 196
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D++T+HTPL + TR+ INA+ + + GV+IIN RGG++ E D AL+SGK
Sbjct: 197 CDFLTVHTPLTDETRDLINAERIATMRPGVRIINCARGGIVNEDDLADALESGK 250
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 165 bits (402), Expect = 4e-40
Identities = 74/174 (42%), Positives = 116/174 (66%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID +A ++G+ V+N P N +S E T ++L ++R++ A+ +L GRWDR + G
Sbjct: 77 DNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQSLVEGRWDRKKFMG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 357
+++AGKTL I+G+GR+GREVA+R AF M+++ FDPF++ DQ ++ ++D+ P
Sbjct: 137 TQVAGKTLGIVGMGRIGREVASRAQAFDMDVVAFDPFLTDDQAESLKVRRVATVDDMLPQ 196
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DY+T+HTPL TR I + L++ K G++IINV RGG+ ++ LKSGK
Sbjct: 197 IDYLTVHTPLTPETRGLIGMEQLEKVKPGLRIINVARGGIYDSEAMVEGLKSGK 250
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 165 bits (401), Expect = 5e-40
Identities = 80/172 (46%), Positives = 110/172 (63%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+ A LK G W++ LY G
Sbjct: 87 DNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQAMADLKQGNWNKHLYAG 146
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKTL+++GLGRVGREVA RM AFGM I +DP ++ + A + L + A
Sbjct: 147 IELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAYDPAIADEDAALLDIELLPLHENLLRA 206
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D IT+H+ L EST N + + L K GV I+N RGG+I E +AL SG
Sbjct: 207 DVITIHSALDESTYNLLGKETLSLTKPGVIIVNCARGGIINEVALAEALASG 258
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 165 bits (400), Expect = 7e-40
Identities = 77/173 (44%), Positives = 113/173 (65%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+++++A K + V+N P +LSA ELTC +++ L R + P G+WD+ + G
Sbjct: 75 DNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP-------GKWDQEEFMG 127
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL GKTL ILGLGR+GREV T+M AF M +GFDP S + A F ++ LE++WPL
Sbjct: 128 TELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDPISSPEIAASFGVQQLLLEELWPLC 187
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+IT+HTPL+ ST +N CKKG++++N RGG++ E L A +SG+
Sbjct: 188 DFITVHTPLLLSTTGLLNDSTFAWCKKGMRVVNRARGGIVDEGAMLCAPQSGQ 240
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 165 bits (400), Expect = 7e-40
Identities = 77/173 (44%), Positives = 113/173 (65%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DVD+A KKG+ V NAP N +SA E T +M+ ++R++ A+ +LKA W R + G
Sbjct: 91 DNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQANASLKAREWKRNKFMG 150
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ GKTL ++GLGR+G EVA R MN++G+DPF+S + + + +I A
Sbjct: 151 VEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDPFISEKRAMELGVKLATVNEIAKEA 210
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DYIT+HTPLI+ TRN ++ + KKGV+++N RGG+I E +AL+SGK
Sbjct: 211 DYITVHTPLIKETRNILDDEQFALMKKGVRVLNCARGGIINEEALARALESGK 263
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 164 bits (398), Expect = 1e-39
Identities = 80/174 (45%), Positives = 111/174 (63%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ A K+G+ V N P +N +SACELT L+L +R++ LK G WDR + G
Sbjct: 79 DNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWDRDSFMG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPL 357
+EL KTL I+GLGR+G VATRM AF M +I +DP++S ++ +F+ K + LED+
Sbjct: 139 TELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPYISDERFKRFNVEKKDTLEDLLKE 198
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D+IT+HTP E T N I+ L+ K GV+I+N RG LI E + LK GK
Sbjct: 199 SDFITIHTPRTEETINIISEKELELMKDGVRIVNAARGKLISEKALCKGLKKGK 252
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 164 bits (398), Expect = 1e-39
Identities = 66/173 (38%), Positives = 117/173 (67%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+ ++KAG+W++ + G
Sbjct: 77 DNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGSVKAGKWEKKRFQG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
ELAG+TL ++G+G +G + R A GM ++ FDPF+SA+ A+ + ++L+ +W A
Sbjct: 137 HELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPFISAEAAAKLGASLVDLDTLWREA 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +++H PL + TR+ ++A L + KKG ++N RGG++ E AL+SG+
Sbjct: 197 DVVSIHVPLTDKTRHLVDATALGKMKKGALLVNCARGGIVDERALADALRSGQ 249
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 164 bits (398), Expect = 1e-39
Identities = 73/174 (41%), Positives = 111/174 (63%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ + KAG+W+++ + G
Sbjct: 76 DNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATASTKAGKWEKSRFMG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPL 357
ELAGKT ++GLG VGR VA R+ M ++ +DPF++ D+ ++ LED+WP
Sbjct: 136 RELAGKTAGVIGLGNVGRLVAQRLAGLDMKVVAYDPFINKDRAISLGLEMVDKLEDLWPR 195
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +T+HTPL + TRN ++A V+ Q K+GV ++N RGG+ E L SGK
Sbjct: 196 VDLLTVHTPLNDHTRNLVDAKVVAQMKEGVILVNCARGGIYNEDALYDGLVSGK 249
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 164 bits (398), Expect = 1e-39
Identities = 79/174 (45%), Positives = 112/174 (64%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV++A +KG+ V+NAP A+++S ELT LML AR++ A+ +LK G WDR + G
Sbjct: 75 DNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDRKRFKG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 357
EL GKTL ++GLGR+G++V R AFGMNIIG+DP++ + + ++ ++
Sbjct: 135 IELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESMGVELVDDINELCKR 194
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+ITLH PL TR+ I + + KK I+N RGGLI E +ALK GK
Sbjct: 195 ADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGK 248
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 162 bits (393), Expect = 5e-39
Identities = 78/173 (45%), Positives = 110/173 (63%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV +A + GV V+NAP +N +SA EL LML ARH+ PA ALK G W RA YTG
Sbjct: 85 DNVDVRAATQAGVMVVNAPTSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRARYTG 144
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL KT+ I+GLGR+G VA R+ AFGM I+ +DP+V A + AQ ++L+ + A
Sbjct: 145 TELYEKTVGIVGLGRIGVLVAQRLSAFGMKIVAYDPYVQAGRAAQMGVRLVDLDTLLAEA 204
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D++++H P T I AD L + K + ++N RGG+++E ALK G+
Sbjct: 205 DFMSVHLPKTPETVGLIGADQLAKVKPSLVLVNAARGGIVEEAALYAALKEGR 257
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 160 bits (388), Expect = 2e-38
Identities = 79/175 (45%), Positives = 111/175 (63%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV +A KKG+ V+N P N +S E T L+ L+R V A ++K G+W++ +TG
Sbjct: 84 DNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASVKEGKWEKKKFTG 143
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF--HCTKMELEDIWP 354
+L GKT I+GLGRVGR+VA R A M +IG+DPF++ + +Q+ H K L D+
Sbjct: 144 QQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDPFITTEISSQYNIHIVK-NLRDLLA 202
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
ADYIT+H L + T+N I + KKGV+IIN RGG+I E D A+K+G+
Sbjct: 203 QADYITIHVTLNKETKNLITSKEFSLMKKGVQIINCARGGVICEEDLYNAIKTGQ 257
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 160 bits (388), Expect = 2e-38
Identities = 72/172 (41%), Positives = 113/172 (65%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ +++ G+WDR ++G
Sbjct: 76 DNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAASMREGKWDRKSFSG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL KTL ++G+GR+G EVA R AFGM ++ +DP+++ + L++I A
Sbjct: 136 VELFKKTLGVIGMGRIGGEVARRAVAFGMKVLAYDPYLAPSRAKAMQVEVATLDEILAQA 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
DYIT+H PL + T+ I+ L +CKKGV++ N RGG+I+E+ + ALKSG
Sbjct: 196 DYITVHMPLTDDTKYMIDEAALAKCKKGVRLFNCARGGIIKESALIAALKSG 247
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 159 bits (387), Expect = 3e-38
Identities = 77/172 (44%), Positives = 109/172 (63%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNI++++A +KG+ V+N PGANA++ E T LML LAR + A+ + AG+W++ G
Sbjct: 77 DNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL GKTL I+GLGR+G EVA R +FGM ++ DP+VS + +++ +A
Sbjct: 137 TELRGKTLGIVGLGRIGLEVARRAASFGMTLVAHDPYVSPAIAHDAKIRLADRDEVLAVA 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
DYITLH L T N INA L KKGV+I+N RG LI + +A+KSG
Sbjct: 197 DYITLHVGLTPQTANMINATTLATMKKGVRIVNCARGELIDDAALAEAVKSG 248
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 157 bits (381), Expect = 1e-37
Identities = 74/170 (43%), Positives = 106/170 (62%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+ +LK+G+W R + G
Sbjct: 75 DNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRANASLKSGQWKRNEFVG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
SEL GKTL I+GLG +G E+A R A M +IG+DPF+S ++ + + ED+ A
Sbjct: 135 SELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPFISMERAKKLQVELLPFEDLLKRA 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
D+ITLH P+ T+ I L+ K V++IN RGG+I E +A+K
Sbjct: 195 DFITLHVPMTGQTKGLIGPKELEMMKPTVRLINTSRGGIIDEEALAKAVK 244
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 157 bits (380), Expect = 2e-37
Identities = 76/173 (43%), Positives = 108/173 (62%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A + GV V+NAP N SA E T +++ L+R++ A ALK +WDR + G
Sbjct: 78 DNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHALKQKQWDRKRFVG 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL KTL I+GLGR+G EVA R MN+I +DPF + ++ Q LED+
Sbjct: 138 VELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPFFTEEKAEQMGVQYGTLEDVLRAG 197
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+IT+HTPL++ T++ IN D K GV+I+N RGG+I E A++SGK
Sbjct: 198 DFITVHTPLLKETKHLINKDAFDLMKDGVQIVNCARGGIIDEDALYDAIQSGK 250
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 155 bits (376), Expect = 6e-37
Identities = 77/173 (44%), Positives = 107/173 (61%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +LK G+W++ G
Sbjct: 78 DNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSLKEGKWEKKALKG 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKTL ++G G +G+EVA R AFGM II +DP A ++L+ ++ +
Sbjct: 138 KELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDP---AKPETDLPVEYVDLDTLFKES 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+I+LH PL ESTR+ IN + + + K GV I+N RGG I E + + SGK
Sbjct: 195 DFISLHVPLTESTRHIINRESIAKMKDGVIIVNTARGGTIDEEALYEEVVSGK 247
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 155 bits (376), Expect = 6e-37
Identities = 71/173 (41%), Positives = 110/173 (63%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+D+A +G+ VINAP N +SA E + ++L +AR++ A +LK W+R + G
Sbjct: 78 DNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHASLKNKEWNRKAFKG 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL KTL ++G GR+G VA R+ +FGM ++ +DP+++ D+ Q +++I A
Sbjct: 138 VELYQKTLGVIGAGRIGIGVAQRLQSFGMKVLAYDPYLTEDKAQQLGVKLATIDEIARQA 197
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D++T+HTPL TR +NAD + K ++IINV RGG+I E D L AL + +
Sbjct: 198 DFVTVHTPLTPKTRGIVNADFFSKAKPTLQIINVARGGIINEDDLLNALNNNQ 250
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 153 bits (372), Expect = 2e-36
Identities = 74/173 (42%), Positives = 110/173 (63%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G
Sbjct: 82 DNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSLKSGKWERSKFVG 141
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 357
E+ GKTL+I+GLG+VG VA GMN+ DP+ S T + L ++ P
Sbjct: 142 VEVKGKTLSIIGLGKVGLTVARLAKGLGMNVNALDPYASPAVAVSASVTLVSSLSELLPT 201
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD++T+HTPLI ST+ I+ L Q K G +I+NV RGG I E LQ+L+SG
Sbjct: 202 ADFLTIHTPLIASTKGMISTAELAQMKPGSRILNVARGGTIDEAALLQSLESG 254
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 151 bits (367), Expect = 7e-36
Identities = 67/172 (38%), Positives = 112/172 (65%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR + A+ + KAG+W+++ + G
Sbjct: 79 DNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAGKWEKSKFMG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL KTL I+G+G++G+ VA MNII FDP+++ + + + L++++ A
Sbjct: 139 VELFQKTLGIVGMGKIGQHVAQIARGIAMNIIAFDPYLTPEVAEKSGVHPVSLDELFQRA 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+IT+HTPL T IN + + KKGV IIN RGG++ E D +AL+SG
Sbjct: 199 DFITVHTPLTPETTGLINKQSIAKMKKGVYIINCARGGIVDENDLAEALQSG 250
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 151 bits (365), Expect = 1e-35
Identities = 67/173 (38%), Positives = 111/173 (64%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++K +W+R + G
Sbjct: 103 DNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWERKQFIG 162
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+E+ KTL ++GLG++G VA A GM ++ +DPF+S ++ Q CT ++L+ ++ A
Sbjct: 163 TEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVDLDLLFSEA 222
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+ITLH P T N INA+ L + K +IIN RGG+I E + A+++ +
Sbjct: 223 DFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETAQ 275
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 150 bits (363), Expect = 2e-35
Identities = 69/172 (40%), Positives = 105/172 (61%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++KAG+W+R+ Y G
Sbjct: 157 DNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVG 216
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
L GKTLA++G G+VG EVA R GM +I DP+ AD+ + + A
Sbjct: 217 VSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVSFDQAISTA 276
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+++LH PL +T+ N + + KKGV++INV RGG+I E ++AL +G
Sbjct: 277 DFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAG 328
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 149 bits (362), Expect = 3e-35
Identities = 68/173 (39%), Positives = 105/173 (60%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A ++G+ V+NAPG N +S E LML AR + A ++K G+W+R + G
Sbjct: 75 DNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGKWERKKFMG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKT ++GLGRVG EVA R A MN++ +DPFVS ++ Q ++ + + +
Sbjct: 135 IELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDPFVSKERAEQIGVKLVDFDTLLASS 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D IT+H P + T I ++ K GV ++N RGG++ E +A+K+GK
Sbjct: 195 DVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGK 247
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 149 bits (360), Expect = 5e-35
Identities = 69/172 (40%), Positives = 108/172 (62%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DVD+A +GV V+NAP +N SA E L+L +R + A +L+A W R+ ++G
Sbjct: 77 DNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+E+ GKT+ ++GLGR+G+ VA R+ AFG ++I +DP+V+ + AQ M +D+ A
Sbjct: 137 TEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPYVAPARAAQLGIELMSFDDLLARA 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+I++H P T I+ + L + K GV I+N RGGL+ E A++SG
Sbjct: 197 DFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSG 248
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 148 bits (358), Expect = 9e-35
Identities = 70/173 (40%), Positives = 106/173 (61%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +LK G WDR + G
Sbjct: 75 DNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKKGEWDRKSFKG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ KTL I+GLGR+G++VA R AF MNI+ +DP++ + ++ + ++++ +
Sbjct: 135 MEVYAKTLGIVGLGRIGQQVAKRAQAFEMNIVAYDPYIPENVASELGIKLLSVDELCAES 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ITLH PL T++ I K IIN RGGLI E A+ GK
Sbjct: 195 EFITLHVPLTTKTKHMIGKTQFDLMKNNTIIINCARGGLIDENALYDAINCGK 247
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 147 bits (356), Expect = 2e-34
Identities = 69/172 (40%), Positives = 107/172 (62%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +++ GRWD+ + G
Sbjct: 76 DNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMREGRWDKKRFMG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL +TL I+GLG++G VA R + M+++G DP++ + A + L+++ +
Sbjct: 136 TELFHQTLGIIGLGKIGSIVADRALSMKMDVLGHDPYIIPEAAAILGVEWVPLDELLARS 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D++TLHTP T +N + L + K GV+I+N RGGLI E + L +G
Sbjct: 196 DFLTLHTPSTSETVRILNRETLARTKPGVRILNCARGGLIDEQALYEFLLNG 247
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 147 bits (355), Expect = 2e-34
Identities = 69/172 (40%), Positives = 105/172 (61%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ++K+G+W R Y G
Sbjct: 186 DNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQRNKYVG 245
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
L GKTLA++G G+VG EV R GM++I DP+ +AD+ + ++ A
Sbjct: 246 VSLVGKTLAVMGFGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAIGVELVGFDEAISTA 305
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+I+LH PL +T +N + + KKGV+IINV RGG+I E ++AL +G
Sbjct: 306 DFISLHMPLTPATSKMLNDETFAKMKKGVRIINVARGGVIDEEALVRALDAG 357
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 146 bits (353), Expect = 4e-34
Identities = 69/172 (40%), Positives = 108/172 (62%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV++A ++G+ V+N P N ++A ELT LML +AR++ A A G + R + G
Sbjct: 74 DNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAALNGDFRRDRFKG 133
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKT+ I+GLGR+G VA+R+ AF M +I +DP++ ++ + ++ L+++ +
Sbjct: 134 VELNGKTVGIIGLGRIGSLVASRLAAFNMRVIAYDPYMPDERFEKCGVKRVTLDELLEQS 193
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+IT+H P E T+ I K+ KKGV+I+N RGG+I E A+K G
Sbjct: 194 DFITIHIPKTEETKKMIGEKEFKKMKKGVRIVNAARGGIIDEKALYNAIKEG 245
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 142 bits (345), Expect = 3e-33
Identities = 70/173 (40%), Positives = 102/173 (58%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID++ A K+G+ V N P N +SA E T +ML L+R++ A+ AL G WDR Y G
Sbjct: 75 DNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQALHEGIWDRKKYMG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ GKTL I+GLGR+G VA R AFGM +I DP++ ++ A+ + + +++ +
Sbjct: 135 VEVKGKTLGIIGLGRIGSRVAVRAQAFGMKVIANDPYLPPEKAAKINVPLLGFKEVLKKS 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DYITLHTPL + T + ++ K V+IIN RG + +AL K
Sbjct: 195 DYITLHTPLTDETYHILSHKEFAIMKDNVRIINCARGKNVDTQALAKALAEHK 247
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 142 bits (343), Expect = 6e-33
Identities = 67/173 (38%), Positives = 106/173 (61%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A +++ G WDR + G
Sbjct: 75 DNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSVRRGEWDRKRFMG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 357
ELAGKTL ++GLGR+G++VA R AF M + +DP++ + + ELE++
Sbjct: 135 VELAGKTLGLIGLGRIGQQVAKRAKAFEMEVTAYDPYIPEKVAEELGVELVDELEELLER 194
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD +++H PL E T I + LK+ K ++N RG ++ E ++ALK G
Sbjct: 195 ADVVSIHVPLTEETEGMIGEEELKRMKSSAFLVNCARGKIVDEEALIKALKEG 247
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 141 bits (342), Expect = 8e-33
Identities = 68/174 (39%), Positives = 105/174 (60%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L+ G W+RA + G
Sbjct: 74 DNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASLRRGEWNRAAFKG 133
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 357
E+A KTL ++GLG VG VA GM ++ +DP+VS ++ + + LE+I+
Sbjct: 134 VEVAEKTLGLVGLGHVGSIVARGALGMGMRVLAYDPYVSEERMRSMNVERAGSLEEIFEE 193
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+++LH P T + + L + K +INV RGG++ ET ALK G+
Sbjct: 194 ADFVSLHVPRTPQTTGMVGEEELARMKPTAYLINVARGGIVDETALYNALKQGE 247
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 140 bits (338), Expect = 2e-32
Identities = 71/175 (40%), Positives = 102/175 (58%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 177
DNIDV +A ++GV V+N PGAN S E L++ +AR++ A AL + GRWDR +
Sbjct: 73 DNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFV 132
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWP 354
G+EL GKTL I+GLGR+G EVA R AFGM ++ +DP+V + T + L + P
Sbjct: 133 GTELHGKTLGIIGLGRIGSEVAVRARAFGMRVLAYDPYVPHSRAEHLGVTLVPSLRGLLP 192
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D++T+H + I A L K +I+N RGG++ E +ALK G+
Sbjct: 193 EVDFLTIHAAKTPESARLIGAAELALMKPTARIVNCARGGMVDEEALYRALKEGR 247
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 138 bits (333), Expect = 9e-32
Identities = 65/174 (37%), Positives = 104/174 (59%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A ++ +WDR + G
Sbjct: 77 DNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHESMLNYKWDRKKFMG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPL 357
EL G+ L I+GLG +G +VA R AFGM ++ +DP++ ++ + ++ L D+
Sbjct: 137 EELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPYIPREKAEKLGVKLVDNLHDMLRE 196
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +T+H PL T+N I+ + K GV I+N RGG+I E ++ ++SGK
Sbjct: 197 IDVLTIHAPLTHETKNMIDEKEFEIMKDGVYIVNCARGGIINEKALIKYMESGK 250
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 138 bits (333), Expect = 9e-32
Identities = 74/185 (40%), Positives = 104/185 (56%), Gaps = 12/185 (6%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---------- 150
DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A ALKA
Sbjct: 152 DNVDLQAATEAGCLVVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFT 211
Query: 151 --GRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 324
G+W R Y G L GKTLA++G G+VG EVA R GM++I DP+ AD+
Sbjct: 212 AQGKWQRTKYVGVSLVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGA 271
Query: 325 TKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQA 504
+ ++ AD+I+LH PL +T N + + K GV+IINV RGG+I E ++A
Sbjct: 272 ELVSFDEAIGRADFISLHMPLTPATSKVFNDESFSRMKNGVRIINVARGGVIDEDALVRA 331
Query: 505 LKSGK 519
L SGK
Sbjct: 332 LDSGK 336
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 137 bits (332), Expect = 1e-31
Identities = 61/171 (35%), Positives = 102/171 (59%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++KAG+W++ + G
Sbjct: 75 DNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASMKAGKWEKKKFQG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ K ++G+GR+GR A R M +I FDP + A+Q + + LE++ A
Sbjct: 135 HEVTAKVAGVVGIGRIGRIFAERAMGLRMKVIAFDPHMPAEQMEKIGVEPVTLEELCQRA 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
DYI++H PL T++ + A+ K +++ RGG++ E +ALK+
Sbjct: 195 DYISVHVPLTPETKHVLGAEQFAMMKPTTMVVDCARGGVVDEKALYEALKT 245
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 136 bits (328), Expect = 4e-31
Identities = 69/175 (39%), Positives = 103/175 (58%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
DNIDV +A K G+ V N P AN + EL T ML RH++P A++AG +D R
Sbjct: 76 DNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAVRAGNFDIRNQLF 135
Query: 178 GSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G EL GKT+ I+G G +GR +A + GMNI+ FDP+V+A+ + LED+
Sbjct: 136 GYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEPYVELTESLEDLLR 195
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++D +TLH P + +T + I+ D + KK +IN RGG++ E ++AL +G+
Sbjct: 196 ISDVVTLHVPYVRATHHLIHKDSFQIMKKDAILINAARGGVVDEKALVEALMNGE 250
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 135 bits (327), Expect = 5e-31
Identities = 65/173 (37%), Positives = 103/173 (59%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDVD+A ++ + V+ A GANALS E TL+ + + +VP + ++AGRW++A Y+G
Sbjct: 105 DNIDVDAASRREIPVVVAAGANALSVAEHAITLLFAVVKRIVPLDSGIRAGRWEKAGYSG 164
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 357
ELAG + ++G G + R+ A FG+ + +DPF + ++ +++D+
Sbjct: 165 KELAGMIIGLVGFGAIARQTAVFARGFGLKVQAYDPFTDETAFVEAGVHRVADVDDLISS 224
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D ++LH PL TRN ++ L K G IIN RGGLI E L+A++SG
Sbjct: 225 SDILSLHCPLTPDTRNLLDDRRLGMMKPGSFIINTARGGLIDEDALLRAVESG 277
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 135 bits (326), Expect = 7e-31
Identities = 71/174 (40%), Positives = 105/174 (60%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+++A +KG+ V+NAP A + EL +M+VLAR + L G W++ + G
Sbjct: 77 DNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLEGEWEKVM--G 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT-KMELEDIWPL 357
ELAGKTL ++G GR+GREVA + A GMN+I +D ++ + +LE++
Sbjct: 135 FELAGKTLGVVGFGRIGREVAKKAKALGMNVIAYDVVDLSETAKEMGVEFTQDLEELLRK 194
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D ++LH PL E TRN IN D +K K G +IN RG + + L+AL+SGK
Sbjct: 195 SDVVSLHVPLTEQTRNMINRDRIKIMKDGAILINAARGEVADYSALLEALESGK 248
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 134 bits (325), Expect = 9e-31
Identities = 60/173 (34%), Positives = 100/173 (57%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+ +A K GV V+N P N ++ E T +M+ L R++ + +L++G+W++ G
Sbjct: 79 DNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSGQWEKKKLQG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ KTL ++G G++G VA R MN+I FDP ++ + L+D++ A
Sbjct: 139 REVFNKTLGVIGFGKIGSIVADRARQLKMNVIVFDPNIARTTIENEGFEYVSLDDLFARA 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DYIT+H P ++ T +N ++ K GV ++N RGG++ E D AL SG+
Sbjct: 199 DYITVHVPKLKQTVGLLNKAAFEKMKTGVMVLNCARGGIVDEADLYDALMSGR 251
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 134 bits (325), Expect = 9e-31
Identities = 72/172 (41%), Positives = 95/172 (55%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ IDV +A G+ V PGAN +S EL LML +ARH+ ++ G W R TG
Sbjct: 82 NTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSRM--TG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
SEL GK L I+G+G +G EVA R +AFGM II +D D + T + + D A
Sbjct: 140 SELYGKVLGIIGMGSIGCEVAKRAHAFGMKIIAYDIRPRQDMIENYGVTYLPMADCLAQA 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+++LH P + T IN D LK K+ +IN RG LI E D ALK+G
Sbjct: 200 DFLSLHAPALPETIGMINKDTLKTMKRTAFLINTARGDLIVEEDLYDALKNG 251
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 133 bits (322), Expect = 2e-30
Identities = 69/175 (39%), Positives = 98/175 (56%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D + A +KG+ V P AN+LS ELT LML L R + A G W+R +TG
Sbjct: 77 DNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEARQDTLTGGWNRLKFTG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD--QCAQFHCTKMELEDIWP 354
+EL GK+ ++GLGR+G ATR AFGMNI+ DPF+ AD Q + + T + L+D+
Sbjct: 137 TELYGKSFGLIGLGRIGSFTATRAKAFGMNILAADPFLKADAPQLKKLNATLLSLDDLLA 196
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D ++ H+PL TR + ++ K IN RG ++ E QAL K
Sbjct: 197 ESDVVSCHSPLTPDTRKMLTYQHFRKMKPDAFFINTSRGEVVDERGLTQALLEHK 251
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 132 bits (320), Expect = 4e-30
Identities = 70/175 (40%), Positives = 103/175 (58%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 177
DNID+++A KKG+ V GAN+LS ELT + L+R +V A L RW+ +
Sbjct: 74 DNIDLEAATKKGIPVTITAGANSLSVAELTIAFIFALSRGLVWAHNKLFLERRWEGTV-- 131
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWP 354
G E++GKTL ++G G +GREV + GMN++ +DP+VS D T + +LE +
Sbjct: 132 GQEVSGKTLGVVGFGSIGREVVKKAVCLGMNVLVYDPYVSKDSVRLLEATPVDDLEQLLK 191
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D+++LH PL EST+N I L KK +IN RG L+ E ++ALK G+
Sbjct: 192 ESDFVSLHVPLNESTKNMIGERELSLMKKSAFLINTSRGELVDEEALVKALKEGR 246
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 132 bits (320), Expect = 4e-30
Identities = 63/172 (36%), Positives = 98/172 (56%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+ID+++ K GV V++ P AN SA +LT L+L ++ A +KAG W+R TG
Sbjct: 77 DHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHKMVKAGEWNRDQITG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
ELAG+ I+GLGR+G VA AFGMN++ +DP+ + + H ++ E++ A
Sbjct: 137 IELAGRNYGIVGLGRIGSRVAELAQAFGMNVVAYDPYQEDEVFERLHIPRLSYEEVLKTA 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D I+ H P T + +N + +G+ +IN RG +I E D +AL+ G
Sbjct: 197 DVISFHVPKTLETEHMLNRSQFEYIHRGIVLINTSRGSVINENDLCEALEKG 248
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 132 bits (320), Expect = 4e-30
Identities = 67/174 (38%), Positives = 104/174 (59%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDVD+A KG+ V+N PG N+LS EL ++L + RH+ + LK +W++ G
Sbjct: 76 DNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPL 357
EL+ KT I+G G VG+ +A + F N + +D F +SA++ ++ ++ LE++
Sbjct: 136 FELSQKTFGIIGFGYVGKNLAQLLKGFQTNTLVYDVFEISAEEQKNYNVRQVSLEELLQN 195
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I+LH P E T +FI+ +K K G IIN RGG++ E L+ LK+GK
Sbjct: 196 SDIISLHIPKNEKTYHFISEPQIKMMKDGAVIINAARGGVLDENYVLKYLKNGK 249
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 132 bits (320), Expect = 4e-30
Identities = 64/172 (37%), Positives = 102/172 (59%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ AG W + LY G
Sbjct: 82 DNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK-LY-G 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
ELAG+TL ++G GR+GR +A AFGM ++G+DPF+ + + + + ++
Sbjct: 140 PELAGRTLGVIGFGRIGRLLAGYAQAFGMTVVGYDPFLDDGELTERGVRPVSFSECLAMS 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+++LH P ++ L+ K G ++N RGGL+ E+ + L SG
Sbjct: 200 DFVSLHLPAEPGRPPLLDQRALRTMKPGACLVNAARGGLVDESALAELLHSG 251
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 132 bits (319), Expect = 5e-30
Identities = 64/172 (37%), Positives = 101/172 (58%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+D+A + GV V NAP N +A E T + AR + A L+ G W ++ Y G
Sbjct: 79 DNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTGEWAKSEYLG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+E+ GKTL ++GLGRVG+EVA R+ + GM+++ +DP++S D+ + +E + A
Sbjct: 139 TEVNGKTLGVVGLGRVGQEVAKRLESLGMDLVAYDPYISEDRAERLGAELVEFDTCLERA 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+++T+HTPL T I+ L + G +IN RGG++ E A++ G
Sbjct: 199 EFLTVHTPLTSETAGMISTAEL-ELMDGGYLINCARGGVVDEDALAAAVEDG 249
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 130 bits (313), Expect = 2e-29
Identities = 70/174 (40%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D IDV A K + V+ PG N + E T L+L L ++++ + + ++G W R TG
Sbjct: 81 DKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRSGGWKRK--TG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMEL-EDIWPL 357
EL KT+ I+GLGR+G+EVA R AFGM +I +D + Q + ++ E+I+
Sbjct: 139 HELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYDIYWDEAFAKQHNVKRVATKEEIFTS 198
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
ADYI+LHT L TR+ INA + KKGV I+N RG ++ D + ALKSG+
Sbjct: 199 ADYISLHTNLTPETRDMINAKTIATMKKGVLILNCARGEIVHTADMVAALKSGQ 252
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 129 bits (312), Expect = 3e-29
Identities = 66/170 (38%), Positives = 99/170 (58%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+ID+ +A +G+ V NAPG NA S +L ML LAR +V A + G W + G
Sbjct: 84 DSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRDGFWGTVM--G 141
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
++ GKTL +LGLG++G+ V R F MNI+G+D + ++ LE+I A
Sbjct: 142 KDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYDLVHHSQFEKEYRVRAATLEEIMSEA 201
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
DYI++H PL+EST+N I+ +L++ + +IN RGG++ ET LK
Sbjct: 202 DYISVHLPLLESTKNIIDRSLLEKMRPTAFLINTSRGGVVDETALYDLLK 251
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 128 bits (309), Expect = 8e-29
Identities = 65/169 (38%), Positives = 98/169 (57%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + + +KAG W + Y G
Sbjct: 75 DNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAGEWPKGKYIG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+AGKT+ I+G GR+GR VA + GMNI+ D + + A+ ++ LE++ +
Sbjct: 135 IEIAGKTMGIVGFGRIGRFVAQMAKSLGMNILASDVIDVSKEVAKIGGRQVPLEELLRQS 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
D +T+H PL T + +NA+ L K G IIN RG +I L+ L
Sbjct: 195 DVVTIHVPLTPETYHLLNAERLSLLKDGAIIINTSRGEVIDHEALLKHL 243
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 128 bits (308), Expect = 1e-28
Identities = 66/174 (37%), Positives = 97/174 (55%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 174
DN+D+ +A + V V + PG+N+ + E +L+L L R ++PA+ + AG W R
Sbjct: 74 DNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDL 133
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G EL+G+TL I+G G +G+ VAT FGM ++ DP +A +EL+ ++
Sbjct: 134 VGFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDPIATAADAEAAGAVLVELDTLYD 193
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD ITLH PL+ TR+ I+ L K IIN RGGLI E + AL +G
Sbjct: 194 GADIITLHAPLLSGTRHMISPRELAMMKPSAIIINTSRGGLIDEDALVTALTNG 247
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 127 bits (307), Expect = 1e-28
Identities = 65/172 (37%), Positives = 95/172 (55%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D ID D+A +G+ V A GANA + E L+L A+ V ++ G WD+A +
Sbjct: 220 DVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQLDMRMREGHWDKATHKS 279
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL G+TL ++GLG +GR VA AFGM ++ FDPF A T + L+ ++ +
Sbjct: 280 VELDGRTLGLVGLGAIGRRVAAIGVAFGMKVLAFDPFAKE---APAGVTLVPLDTLYAES 336
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D +++H PL R +N D L + K+G ++N RGGLI E +AL SG
Sbjct: 337 DVVSMHCPLTADNRRMLNRDTLARFKRGAILVNTARGGLIDEAALAEALTSG 388
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 126 bits (305), Expect = 2e-28
Identities = 58/173 (33%), Positives = 101/173 (58%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ ID+ A K + V+N PGAN+ + E +ML +RH++PA + + G W+++ + G
Sbjct: 75 NTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKGDWEKSKFMG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKT+ ILGLG +G+ + R+ F M ++G+DP +S + ++ I+ +
Sbjct: 135 RELTGKTVGILGLGHIGQLLVKRLAGFEMKVLGYDPMLSPALADKLGVELTTVDRIFAES 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+++LH P + TR +N + + K G +IN R G++ E D L+A+K+ K
Sbjct: 195 DFVSLHIPENDETRGMVNRRLFEMMKPGAMLINCARAGILNEED-LRAVKAEK 246
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 126 bits (304), Expect = 3e-28
Identities = 60/174 (34%), Positives = 104/174 (59%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL---YT 177
+D+ +A ++ + + PG N+++ ELT L + L R V+P + ++KAG+W
Sbjct: 85 VDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRKVIPLALSVKAGKWSELKPKDTM 144
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
G EL GK ILG G +G+ VA + + ++G+DP+VS++ + + LE++
Sbjct: 145 GHELEGKAWGILGFGNIGKRVAQLVTSLNCKVLGYDPYVSSEIMEKHGVKSLSLEELLSK 204
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I++H PL ESTR+ IN++ LK KK +INV RGG+I + ++L++G+
Sbjct: 205 SDIISIHVPLTESTRHLINSERLKTMKKTAILINVSRGGIIDDKALYESLRNGE 258
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 126 bits (303), Expect = 4e-28
Identities = 63/172 (36%), Positives = 95/172 (55%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV++A ++G+ V A GAN+ S EL LM +AR + +K G WD+A G
Sbjct: 89 DNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAREIPHLDARIKTGHWDKATTKG 148
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
++L G++L ++G G +GR + + M + FDP++ AD L++I +
Sbjct: 149 AQLLGRSLGVIGFGEIGRILVGLVQPLHMEVRIFDPYMPADAEISGAERAGSLDEILTAS 208
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D I+LH PL+ TRN I D L + ++ +IN RGGLI E AL+ G
Sbjct: 209 DVISLHCPLMPQTRNMIGRDQLARMRRNAILINTARGGLIDEAALYDALRDG 260
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 125 bits (301), Expect = 7e-28
Identities = 71/176 (40%), Positives = 95/176 (53%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 177
DN+D+ + K+G+ V+N P AN ++A ELT ML R A LK R W R +
Sbjct: 80 DNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNNLKLDRVWRRQDWY 139
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC--TKMELEDIW 351
G+EL K L I+G G +G V R AF M+++ +DP++ + TK EDI
Sbjct: 140 GTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPYIDPSKATDLDIGYTK-NFEDIL 198
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D IT+HTP E T IN D + + K GV +IN RGGL E L+ LKSGK
Sbjct: 199 A-CDIITIHTPKTEETIGMINKDEIAKMKDGVILINCARGGLYNEEALLEGLKSGK 253
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 124 bits (300), Expect = 9e-28
Identities = 63/173 (36%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID++ A ++G+ V+NAP +N +SA EL ++ AR + + +AG WDR + G
Sbjct: 92 DNIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLG 150
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIWPL 357
EL KTL I+GLGR+G VA R MN++ +DP+V ++ + + L+++
Sbjct: 151 LELTDKTLGIVGLGRIGSIVADRAQGLHMNVVAYDPYVPENKFERLGVQRAASLDELLGQ 210
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D +T+HTPL + TR I L K+ ++N RGG+I+E + AL +G
Sbjct: 211 VDALTVHTPLTDETRGMIGERELALLKRDAIVVNAARGGIIEEQALVNALHAG 263
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 124 bits (300), Expect = 9e-28
Identities = 60/171 (35%), Positives = 100/171 (58%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDVD+A K GV V N P AN + + +L+L LAR + + K G+W +L+ G
Sbjct: 79 DNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-SLF-G 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+++ +TL I+GLG +G+EVA R F M ++ +DP++ + + L+ + +
Sbjct: 137 ADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPYIDRTYARKNGIEAVSLDALLQQS 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
D++T+H PL+ TR+ I L+ KK ++N RGG++ ET +AL++
Sbjct: 197 DFVTIHIPLLPETRHLIGERELQLMKKSAYLVNASRGGIVDETALYEALQT 247
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 124 bits (300), Expect = 9e-28
Identities = 63/173 (36%), Positives = 97/173 (56%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+++A KKG+ V N P AN S +L LMLVLAR+++ +K+G W R + G
Sbjct: 84 DNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--G 141
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+E+ GKTL I+GLG++G+ VA R F MN++ +D + ++ T E++ +
Sbjct: 142 TEIYGKTLGIIGLGKIGKGVAKRAKGFDMNVLCYDVYPDLKFSEEYGVTYCSFEELLKQS 201
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +T+H PL T+ I L K +IN RGG++ E AL + K
Sbjct: 202 DIVTIHVPLTPETKGLIGERELGMMKPTAFLINTSRGGIVDERALYNALANKK 254
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 124 bits (298), Expect = 2e-27
Identities = 67/176 (38%), Positives = 100/176 (56%), Gaps = 5/176 (2%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 183
NIDV +A ++G+ V PGANA S E+T LM AR + L+AGRW RA G
Sbjct: 107 NIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWMDAELRAGRWSRA-QDGL 165
Query: 184 ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF---VSADQCAQFHCTKM--ELEDI 348
EL+G+TL +LG G+VG+ VA A GM ++ FDP A +M ++++
Sbjct: 166 ELSGRTLGLLGFGQVGQRVARVALALGMQVVAFDPAFDPACAPGPGAVAGVRMLGSVDEL 225
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
PL+D ++LH PL TR+ ++A + Q +G ++N RG ++ E + AL+SG
Sbjct: 226 LPLSDVLSLHLPLNARTRHLLDAGRIAQLPRGALLVNTARGEVVDEAALIDALRSG 281
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 123 bits (297), Expect = 2e-27
Identities = 58/171 (33%), Positives = 97/171 (56%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ ID+ A K + V+N PGAN+ + E +M+ AR + + +AG W +A G
Sbjct: 76 NTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRAGEWKKAQLQG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKT+ I G G +G+ +A R+ F ++I+ +DPFVS D+ A+F + LE+++ +
Sbjct: 136 FELTGKTVGIAGFGNIGQLLAKRLSGFEVDILVYDPFVSEDKLAEFGAKNVSLEELFAGS 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
D+I+LH P + T N I+ D+L K G ++N R ++ E + K+
Sbjct: 196 DFISLHMPATKETANVISTDLLTSMKDGAVLVNCARYEILDEAALREVKKT 246
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 123 bits (297), Expect = 2e-27
Identities = 65/174 (37%), Positives = 96/174 (55%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A GV VINA + EL +ML +AR + A ++ G+W + G
Sbjct: 79 DNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADRGIRGGKWLKGELGG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPL 357
+EL GK L I+GLG +GR + MNIIG D + A+ + K +L +
Sbjct: 139 TELKGKYLGIVGLGNIGRRLGRLARGMNMNIIGHDVVPIDAEFSREVGLMKTDLNTLLGS 198
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+DY++LH PL++STR+ INA+ L K +I+N RGG+I E +AL G+
Sbjct: 199 SDYVSLHVPLLDSTRHMINAEKLALMKPTSRIVNTSRGGIIDEDALYEALSGGR 252
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 122 bits (295), Expect = 4e-27
Identities = 62/175 (35%), Positives = 103/175 (58%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
DNID+++A +G+ V NAP AN + E TL+L +R ++ +AL+ G ++ R
Sbjct: 76 DNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSALRNGDFEVRNRKF 135
Query: 178 GSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G EL GKTL ++G G +G+ VA + Y GM+++ +DP+V + + + L ++
Sbjct: 136 GIELKGKTLGVVGFGNIGQLVAEKCHYGLGMDVLVYDPYVREENVSSYVQLNQSLSEVLA 195
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D +T+H P + ST + IN + L+Q KK ++N RGG+I E +AL SG+
Sbjct: 196 SSDIVTIHVPYLPSTHHLINEEALQQMKKDAILVNAARGGIIDEIALEKALGSGE 250
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 121 bits (291), Expect = 1e-26
Identities = 66/172 (38%), Positives = 96/172 (55%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N+D++SA ++GV V+ A GAN S EL L L +AR + +++A +W+R+ Y G
Sbjct: 79 NNVDIESATRRGVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWNRSAY-G 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ AGKT I+ G +GR VA + A M II FDP T+ L+++ +
Sbjct: 138 LQFAGKTAGIVAFGAIGRRVAEILRAMDMRIIAFDPHARDRSTTGVDWTET-LDELLQES 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH PL TRN I A L + K G +IN RGGLI E +A+ SG
Sbjct: 197 DLVSLHCPLTPETRNMITAPRLARMKPGAILINTARGGLIDEKALAEAVLSG 248
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 120 bits (290), Expect = 2e-26
Identities = 58/172 (33%), Positives = 94/172 (54%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+NI +D+A KG+ V N P + + E +M+ LAR + A ++ G+W + G
Sbjct: 76 ENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHESMSQGKWQSTEFLG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
S++ KTL ++G G++GR V M++ +DP++S + + +K+ LED+ A
Sbjct: 136 SDINDKTLGVIGGGKIGRRVIEYARGLHMHVNLYDPYLSEEVITRLGASKVSLEDLLSTA 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+I+LH PL T +NA+ K G ++IN GGLI E D + AL G
Sbjct: 196 DFISLHLPLTLETEQILNAETFAMVKPGCRLINCALGGLINEDDLVNALTDG 247
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 120 bits (289), Expect = 2e-26
Identities = 64/173 (36%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D +D+ +A + + V PG N S E L++ +AR A+++G W+R L
Sbjct: 82 DAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAVRSGEWERELTP- 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIWPL 357
+ G T+ I+GLGR+G+ VATR GM+++ +DPF + ++ A+ H K + LE++
Sbjct: 141 -RVWGSTIGIVGLGRIGQAVATRAIGMGMHVLAYDPFPN-EEFAKTHQIKLLSLEELLKQ 198
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+DY+TLH P+ T + IN D L K G +IN RGGLI E ++AL+SG
Sbjct: 199 SDYVTLHLPVTPETIDIINRDTLALMKPGSVLINTARGGLIDENALVEALESG 251
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 119 bits (286), Expect = 5e-26
Identities = 61/172 (35%), Positives = 94/172 (54%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+ID+++ K+G+ V + P + S E L+L + RH+ A + G + TG
Sbjct: 83 DHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERARQGSFAYRGLTG 142
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL G+TL I+GLGR+GR VA FGM+++ +DP +A + + E + +
Sbjct: 143 FELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAYDPAFAASAARPAGVSLVTWEQVLQGS 202
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH P E+TR+ I+A + K GV +IN RG LI E L+AL G
Sbjct: 203 DILSLHVPATEATRHLIDARAFARMKPGVVVINTARGALIDEAALLRALDDG 254
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 119 bits (286), Expect = 5e-26
Identities = 72/197 (36%), Positives = 108/197 (54%), Gaps = 28/197 (14%)
Frame = +1
Query: 10 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 189
DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G E+
Sbjct: 109 DVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEV 168
Query: 190 AGKTLAILGL---------GR------------------VGREVATRMYAFGMNIIGFDP 288
GKTL+I+GL GR VG VA GM++ DP
Sbjct: 169 KGKTLSIIGLGKGELLAIWGRGIHFRYDGGSSGWADRQTVGLTVARLAKGLGMHVNALDP 228
Query: 289 FVSADQCAQFHCTKME-LEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVG 465
+ S A T + L ++ P AD++T+HTPLI ST+ I+ L Q K G +I+NV
Sbjct: 229 YASPAVAASASVTLVSSLSELLPTADFLTIHTPLIASTKGMISTAELAQMKPGARILNVA 288
Query: 466 RGGLIQETDFLQALKSG 516
RGG I E L++L+SG
Sbjct: 289 RGGTIDEAALLESLESG 305
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 118 bits (285), Expect = 6e-26
Identities = 57/172 (33%), Positives = 92/172 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A +G+ V+ + G+N+ + E L L+L + + P + A+K G W + + G
Sbjct: 89 DNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEIQPLNAAVKGGAWPKPTFIG 148
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ G L ++G G +GRE A A GM ++ DP+ A +LE + P
Sbjct: 149 KDFQGAMLGLVGYGGIGRETARMAEALGMEVVVHDPYAPEAAEADGFAAAADLEAMLPAL 208
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH PL +TR+ I+A L K+ I+N RGG+I E AL++G
Sbjct: 209 DILSLHCPLTSATRDLIDARRLAMMKRTAVIVNTARGGIIDEAALADALRAG 260
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 118 bits (284), Expect = 8e-26
Identities = 65/187 (34%), Positives = 104/187 (55%), Gaps = 14/187 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-----------K 147
+NI V ++G+ V NAPGANA + EL ML+ AR++VPA + K
Sbjct: 64 NNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGTDEAMHK 123
Query: 148 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF--H 321
A + + G EL G+TL ++GLG +G +A GMN++G+DP ++ D +
Sbjct: 124 ATEAGKKQFAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDPAITVDAAWRLPSQ 183
Query: 322 CTKME-LEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFL 498
+ E ++D+ AD++TLH PL+++TRN INA L + G ++N R G++ +
Sbjct: 184 VKRAENVDDVLRTADFVTLHVPLLDATRNLINAQRLSLMRSGAVLLNFAREGVVDNAAVI 243
Query: 499 QALKSGK 519
+AL +GK
Sbjct: 244 EALDAGK 250
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 118 bits (284), Expect = 8e-26
Identities = 65/174 (37%), Positives = 93/174 (53%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A ++G+ VIN P S E L+L LA+ VV A + W A G
Sbjct: 81 DNIDLAAATERGILVINTPDGPTESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRG 140
Query: 181 SELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWP 354
E+ GKTL ++GLGR+GR VA GM + +DP A+ A +E L+++ P
Sbjct: 141 VEVRGKTLGVVGLGRIGRRVAQICRQGLGMRVAAYDPLAPAEAFAALDVVHVETLDNLLP 200
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
++++TLH L STR I A L KG +INV RG +I + + AL +G
Sbjct: 201 QSEFLTLHCALTPSTRGLIGARELALLPKGAFLINVSRGAVIDQAALIDALTTG 254
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 118 bits (283), Expect = 1e-25
Identities = 67/175 (38%), Positives = 94/175 (53%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 174
DN+D +A + GV V N PGAN S E L+L ++R V A+ + W DR
Sbjct: 74 DNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSL 133
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
TG EL G+TL ++G G +GR VA AFGM ++ DP F ++L+ +
Sbjct: 134 TGIELEGRTLGLIGFGDIGRHVAPVAEAFGMKVLATDPAYDTS----FDKRLVDLDTLLT 189
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ++LH PL E T N I+ +++ K G +IN RGG+I E AL+SGK
Sbjct: 190 QADVVSLHVPLQEGTENLISRAEIEKMKTGAILINTSRGGVIDEAAVADALRSGK 244
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 118 bits (283), Expect = 1e-25
Identities = 66/173 (38%), Positives = 98/173 (56%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT 177
D+ID D+A + GVG+ PG NA + + T ++L L R VV A+KAGRWDR T
Sbjct: 82 DSIDHDAAKEFGVGISVTPGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWDRVGEAT 141
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
+EL KT+ ++G G +G+ V R+ FG+ ++ FD V A+ C L+ +
Sbjct: 142 PTELYRKTVGLIGAGIIGKAVIRRLLGFGVRVLYFDAMVEKVHGAE-RCG--SLDQLLGS 198
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D ++LH PL+ TR +NA + KG +IN RGGL+Q+ AL+SG
Sbjct: 199 SDIVSLHAPLLADTRELMNAARIALMPKGSYLINTSRGGLVQQPAVFAALRSG 251
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 118 bits (283), Expect = 1e-25
Identities = 59/174 (33%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D +DVD+A ++G+ V+N P A + S E + +L +++++ S A+ W+ R +
Sbjct: 76 DAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSKAIHDDNWNYRKAHP 135
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
G ++ GKT+ ILG GR+G++VA ++ F + +I FDPF + ++ E I+
Sbjct: 136 GRDIEGKTVGILGFGRIGQQVAKKLSGFDVKVIAFDPFAKDVPGVEL----VDRETIFKT 191
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
ADY+ +H P + T++ I AD K K +IN+ RG ++ E+D + ALKSG+
Sbjct: 192 ADYVMVHLPALPETQHSIGADEFKLMKNDAFLINMARGSILVESDLVLALKSGE 245
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 117 bits (282), Expect = 1e-25
Identities = 64/175 (36%), Positives = 93/175 (53%), Gaps = 3/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 177
DNIDV + +G+ VI A GANA S E T +L R S + G+W RA L
Sbjct: 78 DNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWPRARLSE 137
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQ--CAQFHCTKMELEDIW 351
G E GKTL ++G G +GR+ A AFGM ++ DP ++ D + M L+ +
Sbjct: 138 GREALGKTLGLIGFGDIGRQAAALAQAFGMRVVAHDPMLAPDDPVWSATGVVCMTLDALL 197
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D ++LH PL+ +TR+ +NA + K+G +IN RGG++ E AL G
Sbjct: 198 AQSDAVSLHVPLVAATRHLMNAQRIGAMKRGAVLINTARGGVVDEGALAGALLEG 252
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 117 bits (282), Expect = 1e-25
Identities = 63/186 (33%), Positives = 106/186 (56%), Gaps = 14/186 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRAL-- 171
+NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+ L + D+A+
Sbjct: 64 NNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWLTGQKGNDKAIDV 123
Query: 172 --------YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC--AQFH 321
++GSE++GKTL ++GLG +G +VA GM +IG+DP++S + H
Sbjct: 124 AVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPYLSIEHAWNLSHH 183
Query: 322 CTKM-ELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFL 498
++ +L +I+ ADYIT+HTP + T+ +N L +CK GV ++N R + + L
Sbjct: 184 VKRVNDLSEIFEKADYITVHTPATDETKGMLNWKNLSKCKNGVILLNYARDEISDKEAIL 243
Query: 499 QALKSG 516
+A+ G
Sbjct: 244 KAIDEG 249
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 116 bits (280), Expect = 2e-25
Identities = 55/174 (31%), Positives = 104/174 (59%), Gaps = 4/174 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
+NID+++A ++G+ V N PG + ++ L+L +AR +V + ++ G+ W L
Sbjct: 77 NNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKPKL 136
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDI 348
+ G +L GKTL ++G+GR+G+ VA R FGMNI+ ++ ++ Q++ + ++++
Sbjct: 137 FLGYDLYGKTLGVIGMGRIGQAVARRALGFGMNIVYYNRNRLPEEIEKQYNAKYVNIDEL 196
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
++DYI+LHTPL + T + IN + + + K ++N RG ++ E +ALK
Sbjct: 197 VEISDYISLHTPLTKETYHLINKERIAKMKPNAILVNTARGPVVDEQALYEALK 250
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 116 bits (280), Expect = 2e-25
Identities = 59/173 (34%), Positives = 101/173 (58%), Gaps = 4/173 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV+ A K+GV ++ P +A + E+ ML L+R ++ A +++ GRW++ ++G
Sbjct: 97 DNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLEADRSMRNGRWEKHEFSG 156
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK----MELEDI 348
L KTL ++G+G G VA A+GM +IG S ++ F C K +E + +
Sbjct: 157 YLLRDKTLGVVGIGNTGSCVAQMGVAWGMRVIGCVQHPSREREEGF-CEKGIQMLEFDQV 215
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
ADY+++H PL ++TR ++AD L + K G +IN+ RGG++ E ++L
Sbjct: 216 IANADYLSIHVPLKDNTRRLLDADALSRMKPGAYLINLARGGIVDEQALYESL 268
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 116 bits (279), Expect = 3e-25
Identities = 66/175 (37%), Positives = 92/175 (52%), Gaps = 3/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 177
D IDVD+ +G+ + N PG NA + EL TL AR V +G + +
Sbjct: 90 DKIDVDACASRGIKIFNTPGVNARAVAELVLTLATASARQVGSIIAKQSSGILVPKEKCS 149
Query: 178 GSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQF-HCTKMELEDIW 351
G L KT+ ILG+G +G+ VA AF N+I +DPF+ AD + H +E++
Sbjct: 150 GLILHEKTIGILGMGNIGKCVAKIFRGAFDANVIAYDPFLPADAWEEIPHKRATSVEEVL 209
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D IT+H PL TRN I D +K+ KK +IN RGG++ E D QAL G
Sbjct: 210 RSSDVITVHMPLTPETRNLIGYDQMKKMKKTAIVINTARGGIVNEDDLKQALSEG 264
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 115 bits (277), Expect = 6e-25
Identities = 64/175 (36%), Positives = 93/175 (53%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A K+G+ VIN P S E L+L LA+ VV + L+ W A G
Sbjct: 80 DNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASDRVLRTEGWRAARLRG 139
Query: 181 SELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIWP 354
E+ GKTL I+GLGR+GR VA GM+++ +DP V + A + L+D+ P
Sbjct: 140 IEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDPPVPDETFATLDVARAATLDDLLP 199
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
A +++LH L TR+ I A L G +INV RG ++ + + AL G+
Sbjct: 200 HAQFLSLHCALTPETRHLIGARELGLLPPGALLINVSRGAVVDQAALIAALSDGR 254
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 115 bits (277), Expect = 6e-25
Identities = 59/173 (34%), Positives = 92/173 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+++V +A ++ + V PG S E T ++L + R+V+ + ++AG WDR G
Sbjct: 77 DSVNVPAATEQNIAVCRTPGTLHQSVVEHTIGMILAIYRNVISQNKQVRAGDWDRT--AG 134
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
GKTL I+G G +G+EVA GM +I +DP A ++ ++ L++IW +
Sbjct: 135 PRAYGKTLGIIGYGVIGKEVAKAAVLLGMQVIAYDPIAPAGGPSEVE--RVALDEIWRRS 192
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D ++LH P T INA L K +IN RGGL+ E + A+K GK
Sbjct: 193 DVVSLHAPCTPETERIINAQSLALMKDDALLINTSRGGLVNEPELAAAMKGGK 245
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 115 bits (276), Expect = 8e-25
Identities = 57/172 (33%), Positives = 90/172 (52%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+D+A + G+ V NAPG NA + ELT L+L R + AL+ G WDR + G
Sbjct: 83 DNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLILSAMRRIPYLHDALRGGAWDR--FVG 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL G+ + +LG G + R++A ++ F + +I +D F + E++++ +
Sbjct: 141 QELIGRRVGLLGFGNIARKIARKLCGFDVEVIAYDKFPDQVAATKLGVRMCEMDEVLSSS 200
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D + + P + TR ++A + K G IN RG L+ E AL SG
Sbjct: 201 DILVMMMPSLPETRRLMDAGRFARMKPGSIFINTARGALVDEKALYDALVSG 252
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 114 bits (275), Expect = 1e-24
Identities = 71/178 (39%), Positives = 102/178 (57%), Gaps = 6/178 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRA 168
D +D+D+A +G+ V N + GA + E T LML LA+ +VPA TAL W R
Sbjct: 82 DYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDADWALPRL 141
Query: 169 LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII-GFDPFVSADQCAQFHCTK-MELE 342
+ +EL+GKTL I+GLG +G EVA R AF M I+ V A++ A+ + + L+
Sbjct: 142 QRSITELSGKTLGIVGLGHIGEEVARRAVAFDMRIVYAGRERVGAEREARLGGARHVGLD 201
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
++ ADY+TLH PL E+TR+ ++AD L K +IN RG LI + AL+ G
Sbjct: 202 ELLRTADYVTLHAPLTEATRHLLDADRLALLKPTAFVINTARGALIDQDALADALEKG 259
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 113 bits (273), Expect = 2e-24
Identities = 64/172 (37%), Positives = 99/172 (57%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV A + G+ V N P A++ S E+ M LAR + ++ +KAG W + Y G
Sbjct: 78 DNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLWKKKDYVG 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKTL I+G+GR+G E+A + A GM II FD + + + K+E +++ +
Sbjct: 138 VELEGKTLGIIGMGRIGSELAKKCTALGMKIIYFD--LMDIKNIDNNYRKVEFDELLRES 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D+I+++ I T++ I ++ LK+ KKGV IIN RG + E + +L G
Sbjct: 196 DFISIN---ISGTKSIIGSEELKKVKKGVFIINTSRGKALDEEAIITSLNDG 244
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 113 bits (273), Expect = 2e-24
Identities = 65/185 (35%), Positives = 99/185 (53%), Gaps = 12/185 (6%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST---------ALKAG 153
+NI +D A G V N PG+NA + EL L+++ +R+++ A+T +
Sbjct: 60 NNIPIDQATANGTAVFNTPGSNANAVKELIIGLLIMASRNLIAATTYSAQHTEADISQRT 119
Query: 154 RWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD---QCAQFHC 324
D+ + G EL GKTLA++GLG VG VA + GMN+IG+DP++SAD A+
Sbjct: 120 EHDKTQFNGIELTGKTLAVIGLGHVGALVANAALSLGMNVIGYDPYLSADAAWNIAKQVQ 179
Query: 325 TKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQA 504
L D AD++T+H P T + IN D L GV++ N R G++ T + A
Sbjct: 180 RAATLPDAVKQADFVTVHVPKNADTLHLINKDALAAMPTGVQLFNYSRLGIVDNTAVMNA 239
Query: 505 LKSGK 519
L +G+
Sbjct: 240 LATGQ 244
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 113 bits (271), Expect = 3e-24
Identities = 63/185 (34%), Positives = 97/185 (52%), Gaps = 13/185 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 162
+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K +
Sbjct: 61 NNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKELPAEDDVEQK 120
Query: 163 ----RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC-- 324
+ + G+ELAGK L I+GLG +G VA + GM+++G+DPFVS D +
Sbjct: 121 VEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVSVDTAWRISKEV 180
Query: 325 -TKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQ 501
M +E++ DY+T+H PL + TR NAD L+ K ++N RG L+ +
Sbjct: 181 ERAMTIEEVLATCDYLTVHVPLTDKTRGMFNADTLQLVKDNAVLLNFSRGELVDSASVKE 240
Query: 502 ALKSG 516
AL G
Sbjct: 241 ALDDG 245
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 112 bits (270), Expect = 4e-24
Identities = 61/176 (34%), Positives = 95/176 (53%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A + GV V N PG E L++++ R + + G W++ L T
Sbjct: 77 DNIDIPAASRAGVVVANNPGLGGKPVSEHALGLLIMITRDLTAVARDAMTGAWEKRLTTR 136
Query: 181 S-ELAGKTLAILGLGRVGREVATRMYA-FGMNIIGFDPFVSADQCAQFHCTKME-LEDIW 351
EL G TL I+G G VG +A R A F M ++ +DP+VSA+Q AQ TK++ L+ +
Sbjct: 137 RVELTGGTLGIVGCGNVGGWMARRASAGFQMRVLAYDPYVSAEQMAQVGATKVDNLDKLL 196
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+++ H L + T N D Q K G +N RG +++ ++AL+SG+
Sbjct: 197 AEADFVSCHPELNDETDGMFNDDTFGQMKSGAYFVNTSRGAVVRTDALVRALRSGR 252
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 111 bits (268), Expect = 7e-24
Identities = 57/177 (32%), Positives = 102/177 (57%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 168
+ +DVD+A +KG+ V N + + L+L LAR +V + +K+G W+ +
Sbjct: 80 NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWNFNVGKP 139
Query: 169 LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 348
+Y L G+TL ++GLGR+ + +A + AFG+ +I +DP+V A + + + L D+
Sbjct: 140 IY---RLRGRTLGLVGLGRIPQALAKKAQAFGLRVIAYDPYVPAKVADELNVQLLGLNDV 196
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ +DYI++H PL + T+ I+ + KK + I+N RG +I E+ ++AL+ GK
Sbjct: 197 FRQSDYISVHAPLTKETKGMISDEQFNLAKKELIIVNTARGPVIDESALIRALQEGK 253
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 111 bits (268), Expect = 7e-24
Identities = 64/177 (36%), Positives = 97/177 (54%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 171
D+ID+D+ +G+ + N PG + + + L+L R + A+ L+ GRW +
Sbjct: 80 DHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGRWTDLWSSH 139
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDI 348
G ELAG+TL I GLG +GR VA R AFGM ++ + + D+ A F T E+
Sbjct: 140 ILGVELAGRTLGIYGLGDIGRRVARRATAFGMRLVYHNRRRAVDEAGATFAATA---EEF 196
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD + L P TRNF+N + L + G+ ++N+GRG LI + L+AL+SGK
Sbjct: 197 LASADILLLAAPSTGETRNFLNRERLALARDGLVVVNIGRGDLIDDDALLEALESGK 253
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 111 bits (267), Expect = 9e-24
Identities = 63/173 (36%), Positives = 94/173 (54%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDVD A K + V A AN++S E+T +ML +R V + + G+ R + G
Sbjct: 82 DNIDVDYANSKDIVVHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRLV--G 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL K L ++GLG +G+ VA ++ GM I DP + + + K ++I+ +
Sbjct: 140 YELYQKNLGLIGLGAIGQHVAHIAHSMGMTITAHDPHIDKSKVPSYIELKSP-DEIYQYS 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D I+LH PL++STRN IN V ++ K +IN RGGL+ E AL + K
Sbjct: 199 DVISLHLPLLDSTRNIINDSVFEKMKSSAILINTARGGLVDEKSLYTALSNQK 251
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 111 bits (266), Expect = 1e-23
Identities = 60/173 (34%), Positives = 93/173 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ + + G+ V N P ANA + EL LM +AR + ++ AG WDR + G
Sbjct: 84 DNIDIPACTEAGLPVCNTPAANADAVAELAVGLMFSMARWIPQGHASVTAGGWDRRI--G 141
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
++L GKTL I+GLG +G+ +A GM ++ D + A+ + + LE++ +
Sbjct: 142 TQLGGKTLGIVGLGNIGKRLAKLARGLGMQVVATDKYPDEAFAAEHGISFLPLEELLAQS 201
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DYI+LH IN L Q K G K+IN+ RG ++ +AL+SG+
Sbjct: 202 DYISLHVFGGADNAALINEATLAQIKPGAKLINLARGEVVDLDAVAKALESGQ 254
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 110 bits (265), Expect = 2e-23
Identities = 66/179 (36%), Positives = 97/179 (54%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 171
+N+D+ +A +G+ V N G S + T TLML LA ++ A+ GRW +A
Sbjct: 78 NNVDLRAAKAQGIVVCNCQGYGTASVAQHTLTLMLALATSLLRYDHAVAQGRWQQASQFC 137
Query: 172 ---YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 342
Y EL+GKTL I+G G +G+EVA AFGM I+ + Q + H ++ELE
Sbjct: 138 FLDYPIIELSGKTLGIVGYGELGKEVARLAQAFGMKIL----IANLPQRPK-HEDRLELE 192
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ P D+++LH PL E T++ I+A K +IN RGG++ E L ALK G+
Sbjct: 193 ALLPQVDFLSLHCPLTEHTQHLIDAHAFALMKPSAFLINCARGGIVHEQALLDALKQGR 251
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 110 bits (264), Expect = 2e-23
Identities = 61/175 (34%), Positives = 94/175 (53%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV A KG+ V N P A++ S EL M ++R + A+ ++ G+W++ YTG
Sbjct: 79 DNIDVTYARDKGLTVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQCAQFHCTKMELEDIWP 354
+E+ GKTL ++G GR+ REVA R A GM +I D V +F+ ++ +
Sbjct: 139 TEIFGKTLGLIGFGRIAREVAKRAEALGMKVIYNDICGKVVGYDSYEFY---DDINGLLR 195
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+++LH P + I + K G +IN RGG++ E L A+ +GK
Sbjct: 196 EADFVSLHIPYDKKKGYVIGDNEFNAMKDGAFLINCARGGVVSEQALLNAINNGK 250
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 110 bits (264), Expect = 2e-23
Identities = 62/181 (34%), Positives = 102/181 (56%), Gaps = 9/181 (4%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
+NID+D+A + GV V + PG + +L TL+L + R A ++AGR +D
Sbjct: 76 NNIDLDAAKQAGVVVTSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTF 135
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNII---GFDPFVSADQCAQFH---CTKM 333
G+ L G TL I+GLG++G +A R AFGMN+I + V+A + ++
Sbjct: 136 MLGAGLQGATLGIVGLGQIGEAMARRGAAFGMNVIYNARHEKDVAAIDAVNLNTQPTRRV 195
Query: 334 ELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
EL++++ +D ++LH PL + TR+ ++AD L KK ++N RG + E ++ALK+
Sbjct: 196 ELDELFATSDVVSLHCPLTDETRHLVDADALAAMKKTAYLVNTARGACVDEAALVEALKT 255
Query: 514 G 516
G
Sbjct: 256 G 256
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 110 bits (264), Expect = 2e-23
Identities = 62/172 (36%), Positives = 92/172 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D +D +A ++G+ V N PG NA + + T ML L RH ++ G W G
Sbjct: 85 DGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHYAAGHRKVEQGGWGPEGLRG 144
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+L+ T+AILG G +GR VA R+ FG I+ DPF S + Q+ + LE+ A
Sbjct: 145 RDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPFPS-EPGRQY----VALEEAVARA 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH PL ++TR + ++L G ++N GRGG+I E +AL SG
Sbjct: 200 DVLSLHMPLNDATRGLLGDELLATMPSGAYVVNAGRGGVIDEPALARALDSG 251
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 109 bits (263), Expect = 3e-23
Identities = 59/176 (33%), Positives = 90/176 (51%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 171
DNID AG+KG+ V N P + + ELT L+L AR + T + W
Sbjct: 77 DNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPLF 136
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
+ G E+ GKT+ I+GLG +G+ VA R AFGMNI+ P + ++ T + LE++
Sbjct: 137 FLGREVHGKTIGIIGLGEIGKAVAKRAKAFGMNILYTGPNRKPEAESELEATYVTLEELL 196
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+IT++ + I+ + K KK I+N RG ++ E ALK+ +
Sbjct: 197 QTADFITINCAYNPKLHHMIDEEQFKMMKKTAYIVNASRGPIMHEAALAHALKTNE 252
>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=8; Yersinia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 316
Score = 109 bits (263), Expect = 3e-23
Identities = 56/174 (32%), Positives = 90/174 (51%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 174
DNID+ +A K+G+ + N P + + L LAR + +++GRW D+ +
Sbjct: 77 DNIDLSAARKRGMRICNVPDYGIEEVADHAAAMTLALARKLGRYEAGIRSGRWEIDQMVD 136
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
L T+ ++GLGR+ R ATRM FG IIGFDP+V+ + + + +
Sbjct: 137 GVRSLRDTTVGLIGLGRIARAYATRMAVFGCRIIGFDPYVTETEARSAGIEPLPQDKVIA 196
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
A ++LH PL TR+ I+ + + +G +IN RGGL+ E ++AL G
Sbjct: 197 SAHILSLHVPLTPETRDLIDTTAIARMPEGAILINCARGGLVNEVALIEALTRG 250
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 109 bits (262), Expect = 4e-23
Identities = 59/182 (32%), Positives = 101/182 (55%), Gaps = 12/182 (6%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 162
+NI V+ +KG+ V N PGANA + EL +++ +R+++ + K +
Sbjct: 62 NNIPVERCTEKGIVVFNTPGANANAVKELIIASLIMSSRNIINGVSWTKNLEGEEVPQLV 121
Query: 163 ---RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF--HCT 327
+ + GSE+AGK L ++GLG +G VA A GM+++G+DP++S + + H
Sbjct: 122 ESGKKQFVGSEIAGKRLGVIGLGAIGALVANDALALGMDVVGYDPYISVETAWRLSTHVQ 181
Query: 328 K-MELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQA 504
+ L++I+ DYITLH PL T+ I +++ KKG+++ N RG L+ E +A
Sbjct: 182 RAFSLDEIFATCDYITLHIPLTNQTKGMIGEHAVEKMKKGMRLFNFSRGELVDEKVLQKA 241
Query: 505 LK 510
L+
Sbjct: 242 LE 243
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 109 bits (262), Expect = 4e-23
Identities = 60/173 (34%), Positives = 96/173 (55%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D +DVD+A G V A GAN + + T LML + R + + A+ G W R L G
Sbjct: 116 DRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAIARGDW-RVL-VG 173
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
++L GKT+ ++G GR+GR+VA R+ F + ++ + T + L+++ +
Sbjct: 174 ADLTGKTVGLIGFGRIGRQVARRLSGFDVTVLVTSRTPDPEAAG---VTFVALDELIARS 230
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D ++LH PL+ TR+ INA LK K+ ++N RGGLI + L AL++G+
Sbjct: 231 DVVSLHAPLVPETRHVINAATLKAMKRSAVVVNTSRGGLIDDATLLAALEAGE 283
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 109 bits (261), Expect = 5e-23
Identities = 64/173 (36%), Positives = 96/173 (55%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T K G+W + + G
Sbjct: 84 DSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKPV--G 141
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIWPL 357
L+ KT+ I+G+G +G VA R + MNI+G+D + + A K + L+++
Sbjct: 142 ISLSKKTIGIIGVGTIGTAVAKRATGYDMNILGYD--IKKNPLALGLGVKYVGLDELLSE 199
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD+I+LH PL T N +NAD K KKG +IN R LI +L G
Sbjct: 200 ADFISLHLPLTNDTLNILNADKFKLIKKGAIMINTARSQLIDNEALYNSLIDG 252
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 108 bits (260), Expect = 7e-23
Identities = 60/176 (34%), Positives = 91/176 (51%), Gaps = 4/176 (2%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT-- 177
N+D+ +A + GV V APG NA +A E L+L R + + LK+G W Y
Sbjct: 100 NVDLQAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYE 159
Query: 178 --GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
G EL G T+ ++G G +GR VA + AFG +++ DPFV + +ELE++
Sbjct: 160 NAGIELEGSTVGLVGYGAIGRIVARVLAAFGAHVLVADPFVKPEDATADGVELVELEELL 219
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ ++LH L T + +NAD L +G ++N RGGL+ LKSG+
Sbjct: 220 RRSSVVSLHARLTPETHHLLNADNLALLPEGAVLVNSARGGLLDYAPLPGLLKSGR 275
>UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: D-3-phosphoglycerate
dehydrogenase - Microscilla marina ATCC 23134
Length = 322
Score = 108 bits (260), Expect = 7e-23
Identities = 68/177 (38%), Positives = 91/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY 174
DNID + A + + V N P + E LML LAR P ++ W
Sbjct: 83 DNIDCEYARCQQILVENIPDYVHETVAEYAINLMLSLARKSWPVQQTMRQKGWFDITPAS 142
Query: 175 TGSELAGKTLAILGLGRVGREVAT-RMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDI 348
G+EL GKT+ ++G GR+ R VA + F M++I +DP+VSA++ K E LEDI
Sbjct: 143 LGTELNGKTIGLVGFGRIARSVARIAHFGFQMSVIAYDPYVSAEEMELCAVQKAEQLEDI 202
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
P D ++LHT L TRN I L K +INV RGG+I ET L AL + K
Sbjct: 203 LPHCDVVSLHTSLNNDTRNLIGEKQLAMMKSSALLINVARGGIIDETALLIALSTQK 259
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 108 bits (260), Expect = 7e-23
Identities = 58/173 (33%), Positives = 95/173 (54%), Gaps = 2/173 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ + ++AG W++
Sbjct: 174 NQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSKNC 233
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQCAQFHCTKMELEDIWP 354
E+ GKTL I+G G +G +++ AFGM++I FD P + Q LED+
Sbjct: 234 WEIRGKTLGIVGYGHIGSQLSVLAEAFGMSVIYFDVVPIMPLGSARQVD----TLEDLLS 289
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
AD+ITLH P I T + A+ Q KKG IN RG ++ + AL+S
Sbjct: 290 RADFITLHVPEIPDTIGMMGAEQFSQMKKGAFFINNARGKVVDLSALCDALES 342
>UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 727
Score = 108 bits (259), Expect = 9e-23
Identities = 73/181 (40%), Positives = 95/181 (52%), Gaps = 9/181 (4%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR----HVVPASTALKAGRWD-- 162
DNIDV +A + G+ V +APG + T +L+L L R H S K D
Sbjct: 254 DNIDVKAATELGIAVCHAPGDYVEDVADSTLSLILDLFRRTYWHAKSYSETRKTIGADQV 313
Query: 163 RALYTGSE-LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSA--DQCAQFHCTKM 333
R GS+ + G L ILG GRVG V R AFG++II +DPFV D+ F
Sbjct: 314 RENAVGSKKVRGSVLGILGCGRVGTAVGLRARAFGLHIIFYDPFVREGHDKALGFERV-Y 372
Query: 334 ELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
+++ +D I+LH L + TR INAD L+QCK GV I+N GLI E D ALK+
Sbjct: 373 TMDEFMSRSDCISLHCNLGDETRGIINADSLRQCKSGVYIVNTSHAGLINENDLAAALKN 432
Query: 514 G 516
G
Sbjct: 433 G 433
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 107 bits (258), Expect = 1e-22
Identities = 65/179 (36%), Positives = 96/179 (53%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 168
+N+DV++AGK+G+ V N P + S + T L+L LA HV +A+KA W D +
Sbjct: 81 NNVDVEAAGKRGIPVANIPAYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRSPDHS 140
Query: 169 LYTGS--ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 342
+ EL G TL I+G G +GR VA AFGM I+ + P V AD + L+
Sbjct: 141 FWKTPIVELDGLTLGIVGYGTIGRAVARVGAAFGMKIMAYAPRVPAD-LGPVPVRFVSLD 199
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+++ +D ++L+ P F+N+ +L K +NV RGGL+ E D AL SGK
Sbjct: 200 ELFAGSDVVSLNCPQTAENTGFVNSRLLSLMKPSAFFLNVARGGLVNEVDLAAALHSGK 258
>UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 327
Score = 107 bits (258), Expect = 1e-22
Identities = 59/175 (33%), Positives = 98/175 (56%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 177
D I V+ A + + V N P +N + E +L +AR A + W R +
Sbjct: 76 DFIPVERATRADIAVANLPDSNTQAVAEHVVGAILAMARGFDRLPRAWRNDGWLVRQTFQ 135
Query: 178 GSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G EL +T+ I+GLGR+G +VA ++ FGM ++G D A + + + +E+++
Sbjct: 136 GIELRDRTVGIVGLGRIGLQVAAALHHGFGMRVLGCDN--GAREGLPSYVDQTSIENVFS 193
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D+ITLH PL++STR+ +NA++L K G ++N RGGLI + + AL+SG+
Sbjct: 194 GSDFITLHAPLVKSTRHLVNAELLSLAKPGALLVNAARGGLIDDDALVAALRSGQ 248
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 107 bits (257), Expect = 2e-22
Identities = 57/173 (32%), Positives = 93/173 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ +DV++A G V A G N S + +M+ + R A +A+KAG+W+ + G
Sbjct: 88 EKVDVEAARDLGRVVAIAAGGNDASVADQVIGMMISIGRRFQEAQSAMKAGKWN--ILVG 145
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL + + I+G GR+GR +A R+ F I+ P ++++ F + E + A
Sbjct: 146 TELYRRKVGIVGFGRIGRSLARRLSGFEAEILVCAPRLASEDIETFGLRHVAFETLLKEA 205
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DYI++H PL TR+ NA + K +IN RGGL+ +T L AL+SG+
Sbjct: 206 DYISVHAPLTPETRHMFNAAAFGRMKPSAVLINSARGGLVDDTALLAALESGQ 258
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 107 bits (257), Expect = 2e-22
Identities = 62/187 (33%), Positives = 96/187 (51%), Gaps = 14/187 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 171
+NI +D KGV V N PGANA EL ML+ +R ++ + + + +
Sbjct: 61 NNIPLDKCADKGVVVFNTPGANANGVKELVLCGMLLASRDIIGGNKWVANNTDNENISKD 120
Query: 172 -------YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF---- 318
+ G+E+ GK L ++GLG +GR VA + GM + G DPF+S +
Sbjct: 121 MEKAKKNFAGNEIKGKKLGVIGLGAIGRLVANAAESMGMEVYGNDPFISVEGALSLKRDV 180
Query: 319 HCTKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFL 498
H K E+I+ D+IT+HTPL++ T+ IN + + K GV ++N R L+ +
Sbjct: 181 HLVKTR-EEIFKECDFITVHTPLVDDTKKMINKETIAMMKDGVVVLNFARDLLVDDEAMC 239
Query: 499 QALKSGK 519
+AL SGK
Sbjct: 240 EALASGK 246
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 107 bits (257), Expect = 2e-22
Identities = 56/173 (32%), Positives = 91/173 (52%), Gaps = 3/173 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N++V A K+G+ V N G NA + + T LML R++ A ++K G W +
Sbjct: 107 ENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEFSNS 166
Query: 181 S---ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
EL GK + ++G G +GR VA ++ FG+ + +DPFV + C ++ E ++
Sbjct: 167 DWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVYDPFVDEETIRGAGCIPVDKETLF 226
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
+D+I+LH L EST+N + + K +IN R GL+ E L AL+
Sbjct: 227 KESDFISLHARLSESTKNLVGEKEISLMKPTAYLINTARAGLVDENALLAALR 279
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 107 bits (257), Expect = 2e-22
Identities = 66/194 (34%), Positives = 103/194 (53%), Gaps = 21/194 (10%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELT-CTLMLVLA------RHVVPASTALKAGRW 159
+NI V + G+ V N PGANA + EL C+L+L +HV + G +
Sbjct: 93 NNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINVEENGDY 152
Query: 160 ---------DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA 312
D+A++ G+E+ GKTL ++GLG +G V GMN+IG+DP +S +
Sbjct: 153 AKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSRVVNAALGLGMNVIGYDPVLSLEAAW 212
Query: 313 QFHCTKM----ELEDIWPLADYITLHTPLIES-TRNFINADVLKQCKKGVKIINVGRGGL 477
+ KM +L++++ LADYIT+H P I+ T + I+A L +CK GV ++N RG +
Sbjct: 213 RLPGDKMSRADDLDELFALADYITIHVPYIKGVTHHLIDAKSLAKCKPGVNLLNFARGEI 272
Query: 478 IQETDFLQALKSGK 519
I + +GK
Sbjct: 273 IDGSAVRAGYDAGK 286
>UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga
hutchinsonii ATCC 33406|Rep: D-lactate dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 329
Score = 107 bits (256), Expect = 2e-22
Identities = 54/167 (32%), Positives = 88/167 (52%)
Frame = +1
Query: 19 SAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGK 198
+A + G+ V N P + + E T T++L L RH+V A +K + G + K
Sbjct: 85 AAHRLGMHVANVPAYSPHAIAEHTVTMILALTRHIVEADNRVKQSNFILDPLVGFNIHHK 144
Query: 199 TLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLH 378
T+ I+GLG++G A ++ FG + FDP+ + + ++ +E++ +D I +H
Sbjct: 145 TVGIIGLGKIGGLTAKILHGFGCTLQAFDPYPNQEYTDKYGLQYKSIEEVLATSDIIVIH 204
Query: 379 TPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
PL T+ I+AD +K K GV I+N GRG +I D + L SGK
Sbjct: 205 APLNAHTKYLIHADSIKTMKDGVMIVNTGRGAIINTKDAIDGLTSGK 251
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 107 bits (256), Expect = 2e-22
Identities = 59/171 (34%), Positives = 97/171 (56%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 183
+ID+ +A + G+ V+ G + +A ELT L+L LAR + L+ GRW + G
Sbjct: 84 SIDLRAAEELGI-VVCGTGGSPTAAPELTWGLLLALARSISFEDRNLREGRWQSTV--GF 140
Query: 184 ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLAD 363
ELAGKTL +LGLG++GR VA AFGM++I + P ++ + AQ K+ E+++ +D
Sbjct: 141 ELAGKTLGVLGLGKIGRRVAAYGQAFGMDVIAWSPNLTGEAAAQAGVRKVSKEELFRDSD 200
Query: 364 YITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+++H L E +R + + L+ ++N RG L+ E ++AL G
Sbjct: 201 VVSVHVRLSERSRGVVGEEELRLLGPRGVLVNTSRGPLVDEDSLIRALNEG 251
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 107 bits (256), Expect = 2e-22
Identities = 59/173 (34%), Positives = 94/173 (54%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+IDV++A + G+ V+ APGAN+ ELT L+L +R + LK+G+W+R G
Sbjct: 95 DSIDVEAAERLGINVLTAPGANSQGVAELTIALILAGSRSIPWHDAQLKSGQWNRR--PG 152
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+E++GK L ++G G++GR VAT GM +I FD + + E + +
Sbjct: 153 NEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEYPVTSFAPSPDFSWAPRERVLSSS 212
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++LHTP S + + A ++ + G +IN R LI + LQAL SG+
Sbjct: 213 HVVSLHTP--PSGQPVLGAAAIRLLQWGTGVINTARASLIDDEALLQALDSGQ 263
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 106 bits (255), Expect = 3e-22
Identities = 61/172 (35%), Positives = 90/172 (52%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+++A + + V N P A A + ELT LML R + +++ G W R+ G
Sbjct: 83 DNVDLEAARRLNIQVSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWPRS--QG 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
LA +T+ I+GLG +GR VA AFG +I DP + Q A + L + A
Sbjct: 141 RLLAARTVGIVGLGHIGRRVAKLCQAFGAQVIAHDPHL---QLAPDGVELVALTTLLEQA 197
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D +TLH P + I+A+ + + K G +IN RGGL+ ET AL +G
Sbjct: 198 DLVTLHLPYSPAVHYLIDAEAIDRMKPGTILINAARGGLVDETALCAALNTG 249
>UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family; n=2; Cyanobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase family -
Synechocystis sp. (strain PCC 6803)
Length = 318
Score = 106 bits (255), Expect = 3e-22
Identities = 56/174 (32%), Positives = 94/174 (54%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D ID+ +A + G+ N P ++ +++LAR + A++ G W + G
Sbjct: 85 DAIDLAAAKQLGILTSNTPNVFGDEVADVAIGYLILLARELHCIDQAVRQGEWLKI--RG 142
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPL 357
L GKT I+G+G +G+ +A R+ + G+ ++G+DP +SAD C Q + L+D+
Sbjct: 143 HSLRGKTAGIIGVGSIGQAIAVRLQSMGLKLLGYDPHPISADFCEQTGLHPVPLQDVLQQ 202
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD + L L + +NAD Q K GV +INV RGGL+ + ++ L++GK
Sbjct: 203 ADCLFLACNLTPDNFHLLNADTFDQMKPGVWLINVARGGLVDQAALIETLQTGK 256
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 106 bits (255), Expect = 3e-22
Identities = 57/179 (31%), Positives = 93/179 (51%), Gaps = 7/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR----- 165
DNID++ A K+G+ V N P + +L L+L ARHVV +++G W +
Sbjct: 79 DNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAW 138
Query: 166 --ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMEL 339
+ G ++ GKT+ I+GLGR+G+ +A R F M I+ + + + + L
Sbjct: 139 HPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRILYYSRTRKEEVERELNAEFKPL 198
Query: 340 EDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
ED+ +D++ L PL T + IN + LK KK +IN+ RG ++ ++ALK G
Sbjct: 199 EDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEG 257
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 106 bits (254), Expect = 4e-22
Identities = 59/174 (33%), Positives = 91/174 (52%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
++ID+ +A GV V+ A GANA S E LML L + V ++ G WD+ Y G
Sbjct: 81 NDIDLAAAKALGVPVLAAVGANAHSVAEHAFMLMLALIKDVRNQDAYVRGGGWDKKGYRG 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPL 357
EL G+ L ++G+G +GR +A + GM I +DPF A H +++ L+++
Sbjct: 141 RELRGRVLGLVGIGMIGRALAAMVQPIGMTTIAYDPFAPAAAFGP-HARRVDSLDELLAQ 199
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D ++LH PL T+N I K +IN RG ++ E + AL SG+
Sbjct: 200 SDVVSLHCPLTPQTQNLIGVREFGLMKPSALLINTARGEVVDEPALVGALTSGR 253
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 105 bits (253), Expect = 5e-22
Identities = 58/186 (31%), Positives = 100/186 (53%), Gaps = 14/186 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 162
+NI V+ +G+ V N PGANA + EL ML+ +R+++PA ++ D
Sbjct: 69 NNIPVNQMSARGIPVFNTPGANANAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNL 128
Query: 163 -----RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT 327
+ ++G EL G+TL ++GLG++GR+VA GM ++G+DP ++ D
Sbjct: 129 QVEAGKKQFSGLELPGRTLGVIGLGKIGRQVADIAIKLGMKVLGYDPKITIDSAWSLPAE 188
Query: 328 KM---ELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFL 498
++ED+ + +I+LH PL +STR+ IN ++ +K ++N R ++ E L
Sbjct: 189 VQKANQIEDLIRRSQFISLHVPLNDSTRHLINDSLISCMQKNTILLNFSRDAIVDEDAVL 248
Query: 499 QALKSG 516
+KSG
Sbjct: 249 TGIKSG 254
>UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;
n=7; Clostridium|Rep: (R)-2-hydroxyisocaproate
dehydrogenase - Clostridium difficile
Length = 331
Score = 105 bits (253), Expect = 5e-22
Identities = 64/175 (36%), Positives = 89/175 (50%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG--RWDRALY 174
D I D + G+ V N P + + EL T + L R + G RW L
Sbjct: 81 DMIHFDLVNENGLIVTNVPSYSPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELL 140
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G+E+ T+ ++G G++G A G N+I FD + ++D K LED+
Sbjct: 141 -GTEVRSITVGVIGTGKIGATSAKLFKGLGANVIAFDQYPNSD-LNDILTYKDSLEDLLK 198
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ITLHTPL+E T++ IN D L K G I+N GRGGLI D ++AL+SGK
Sbjct: 199 EADLITLHTPLLEGTKHMINKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGK 253
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 105 bits (253), Expect = 5e-22
Identities = 51/175 (29%), Positives = 98/175 (56%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ IDV +A ++GV V N PG N+++ EL L++ L R + L+AG+WD+ ++
Sbjct: 74 NTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALLRAGKWDKKTFSE 133
Query: 181 SE-LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWP 354
++ L G+TL + G+G +GREVA R A GM ++ + + Q + +L +
Sbjct: 134 AQGLYGRTLGVAGVGSIGREVARRAQALGMRVVAWSRSLDDRQAKLLGVERAPDLAALAR 193
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D+++LH L + TR ++ +VL+ + G ++N R ++ + L+ ++G+
Sbjct: 194 ESDFLSLHLALSKETRGIVSREVLEALRPGAALVNTARAEIVDQAALLELARAGR 248
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 105 bits (253), Expect = 5e-22
Identities = 63/176 (35%), Positives = 91/176 (51%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +A G+ V N PG NA S ELT +++ L R + K G W +
Sbjct: 78 DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP 137
Query: 181 S--ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQCAQFHCTKMELEDIW 351
S E+ GKT I+G G +GREVA AFG N+I +D + + + + T EL ++
Sbjct: 138 SSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIYYDLRRLEPAEEKRLNVTYHELNELL 197
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I++H PL T+N I+ L K +INV RG ++ E +ALK K
Sbjct: 198 QKSDIISIHLPLTPDTKNLISERELALLKPTALLINVARGNIVDEVALYRALKENK 253
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 105 bits (252), Expect = 6e-22
Identities = 62/173 (35%), Positives = 92/173 (53%), Gaps = 3/173 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 171
+NIDV++A K + V N G NALS E T L L R ++ A ++ +GRW++ A
Sbjct: 82 NNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALLRRLIYAHNSVLSGRWEQDEMAN 141
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
EL GKT I+G+G GREV R+ +G+ II D A+ ++ + + +
Sbjct: 142 LGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD-VRRAEDIEEYGVEFRDFDALL 200
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
AD ++LH PL E TR I LK K +INV RG ++ E ++A+K
Sbjct: 201 READIVSLHVPLTEETRGMIGERELKMMKNSAILINVARGEVVDENALVRAIK 253
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 105 bits (252), Expect = 6e-22
Identities = 56/173 (32%), Positives = 92/173 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D++D+D+A KGV V NAPG + + E ++L R + A ++ ++D + G
Sbjct: 77 DDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAFEG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKT+ I+G G++G VA FGM++I +D V + + L+ + +
Sbjct: 137 RELRGKTMGIIGTGQIGLRVAEIARCFGMDVIAYD--VRRNPAVAEKLRYVGLDRLCAES 194
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+IT+H PL TR I+ + + K G IIN RG ++ + L+AL G+
Sbjct: 195 DFITVHLPLTSDTRGLIDEESFRLMKPGAVIINTARGPVVDQAALLRALDEGR 247
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 105 bits (251), Expect = 8e-22
Identities = 58/172 (33%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
DNIDV++A +KG+ V N P N LS E T ++L L++ + A+++G W R
Sbjct: 75 DNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMDKAVRSGNWGARNSNI 134
Query: 178 GSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
E+ GK L I+G+G +G VA + + GM I+ +DP+V + E+++
Sbjct: 135 SVEIEGKVLGIVGMGNIGSLVAKKCHDGLGMKIVAYDPYVKEKFRGYDYKFVDTREELFK 194
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
+D++TLH P I TR I +++ K +IN RG +I E ++ALK
Sbjct: 195 ESDFVTLHCPDIPETRGMITRELIYSMKHTAYLINAARGTVIDEQALIEALK 246
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 105 bits (251), Expect = 8e-22
Identities = 68/197 (34%), Positives = 98/197 (49%), Gaps = 26/197 (13%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--------- 156
NID +A +G+ V+ PG NA +A ELT LML LARH+ + ALK G
Sbjct: 79 NIDTQAAQARGIRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQADNASA 138
Query: 157 -----------WDRA------LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 285
WD + ++ GSEL KTL ++G G +GR VA AFGM ++ D
Sbjct: 139 ATQQGLRRDVVWDVSPESPYEVFKGSELRNKTLGLVGYGNIGRRVARIARAFGMAVLVVD 198
Query: 286 PFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVG 465
PFV+A+ + K LE ++ AD ++LH + +NA +L K G +IN
Sbjct: 199 PFVAAEDINEPGLQKTTLEALFREADIVSLHLSSGPHSDGLVNAALLNSMKPGALLINTS 258
Query: 466 RGGLIQETDFLQALKSG 516
R ++ E + AL+ G
Sbjct: 259 RAAVVDEAALIDALRHG 275
>UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23;
Proteobacteria|Rep: Glycerate dehydrogenase -
Methylobacterium extorquens (Protomonas extorquens)
Length = 314
Score = 104 bits (250), Expect = 1e-21
Identities = 62/178 (34%), Positives = 93/178 (52%), Gaps = 6/178 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 171
D +D +A +G+ V+N + E LM L R +VP + +++ G W+++
Sbjct: 77 DVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRAIVPYANSVRRGDWNKSKQFC 136
Query: 172 ---YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 342
Y ++AG TL I+G G +G+ +A R A GM ++ FD F ++LE
Sbjct: 137 YFDYPIYDIAGSTLGIIGYGALGKSIAKRAEALGMKVLAFDVFPQDGL--------VDLE 188
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
I +D ITLH PL T+N I A+ LK+ K+ +IN RGGL+ E LQALK G
Sbjct: 189 TILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDG 246
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 104 bits (249), Expect = 1e-21
Identities = 61/177 (34%), Positives = 94/177 (53%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D++DV +A + G+ V+ APG+N S E LM A+ +V + ++ G + R+ Y
Sbjct: 76 DDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFAIRSSYK 135
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV---SADQCAQFHCTKMELEDI 348
EL KTLA++G GR+G +A A GMN+ +DPFV + +Q +CT EL+D+
Sbjct: 136 AYELNHKTLALIGYGRIGSILAQMSKAIGMNVKVYDPFVKQGTIEQEGYIYCT--ELDDV 193
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ I++H PL TRN I + +IN RG +I E + L+ GK
Sbjct: 194 IRDSHVISIHVPLTNETRNLIGEHEFSLMNEHTILINCARGEVIDEPVLTKVLQEGK 250
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 103 bits (248), Expect = 2e-21
Identities = 60/174 (34%), Positives = 87/174 (50%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNIDV A + GV V+ GANA+S E T + L R V + G W+R G
Sbjct: 83 DNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELDADCRRGGWERT--PG 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELED-IWPL 357
EL G +LG G GR A + GM+I+ +DPF A++ AQ +E +
Sbjct: 141 RELHGGVWGLLGAGATGRACARLARSLGMSIVAYDPFADAEKLAQEGIELVEHPALVAAR 200
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ++ H P T + IN ++L K ++NVGRG ++ E AL++G+
Sbjct: 201 ADVMSCHLPATRGTAHLINGELLTVMKPTAVLVNVGRGEVVDENALADALETGR 254
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 103 bits (248), Expect = 2e-21
Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D + + G+ + N PG ++ ++ LAR +KAG W ++ G
Sbjct: 125 DNVDFAACQRLGLPISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AG 182
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL- 357
LAGKT+A+ G G +GR A R++A M I+ +DPF A + +E +WP
Sbjct: 183 ISLAGKTVALAGFGDIGRNTARRLFAAEMKIVAYDPFFKAASGLE----AVE-PAVWPQR 237
Query: 358 ---ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+I + L + R+ + +D L + K GV+++NV RG LI E AL SGK
Sbjct: 238 MEEADFIVITCALTKENRHMLGSDALARVKPGVRVVNVARGPLIDEAALAAALASGK 294
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 103 bits (248), Expect = 2e-21
Identities = 55/173 (31%), Positives = 84/173 (48%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+ID+D G+ V N P + E L+L ++RH+V + + G + + G
Sbjct: 76 DHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAVSRHIVTGAERTRRGDFSQHGLRG 135
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKTL +LG GR+GR V FGM I+ +D F A ++L + A
Sbjct: 136 FELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVAYDLFPDAAVAEHLGYEYLDLHVLLSQA 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +TLH P T + + KKG +IN RGG++ + ++AL + K
Sbjct: 196 DVVTLHVPATPQTHHLLGDPEFAAMKKGAVLINTARGGVVDTSALVRALSARK 248
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 103 bits (248), Expect = 2e-21
Identities = 59/172 (34%), Positives = 88/172 (51%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D++D+++A +GV V A ANA + E LML L R + ++AG W + + G
Sbjct: 86 DSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLALVRQLPQLDQQVRAGGWAGSNWQG 145
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ G T+ I+G G +GR A A G ++ P A Q F C + +L + P
Sbjct: 146 RDFRGSTVGIVGYGAIGRATAQLAAALGAKVLVLRP---AGQADDFDC-EPDLRRLLPRV 201
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH PL E TR I A+ L + G +IN RG ++ E L AL+SG
Sbjct: 202 DILSLHCPLTEQTRGLIGANELALLRPGSLLINTARGPVVDEAALLAALESG 253
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 103 bits (247), Expect = 2e-21
Identities = 54/176 (30%), Positives = 95/176 (53%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 171
+++D+D+ ++GV V N PG + + L+L AR VV ++AG W D A
Sbjct: 78 NHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTEVDPAW 137
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
G+E+ GKT+ ++G GR+G+ A R F ++ P + A+ ++ LE +
Sbjct: 138 MLGTEVTGKTVGVVGFGRIGQAFARRARGFDTRVLYTSPRDAGVAWAE----RVGLERLL 193
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+++LH PL+ +TRN ++ + L K G ++N RGG++ + +AL G+
Sbjct: 194 AEADFVSLHVPLVPATRNLLSRERLALLKPGAIVVNTARGGVLDDAALAEALADGR 249
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 103 bits (247), Expect = 2e-21
Identities = 57/174 (32%), Positives = 94/174 (54%), Gaps = 3/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 177
DN+D+D+ + G+ NA G NA + E L+L +++ + +K + L YT
Sbjct: 80 DNVDIDACTQYGIWAANAAGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDENELQYT 139
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGF--DPFVSADQCAQFHCTKMELEDIW 351
GSEL GKT+ I+G G VG++VA F MNI+ + +P V +D + + + +
Sbjct: 140 GSELKGKTIGIIGFGAVGKKVAEFCRVFDMNILVYARNPVVQSDSFVKM----TDFDTLV 195
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
+D +++H L + T+ IN DV K+ K +N RGG++ E D + ALK+
Sbjct: 196 GASDIVSVHVSLNQQTKQLINKDVFKKMKNTALFVNTARGGIVNERDLIDALKN 249
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 103 bits (247), Expect = 2e-21
Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 6/176 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ ID +SA ++GV V N PG NA++ EL LML L R V L+AGRWD+ Y+
Sbjct: 74 NTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDLRAGRWDKKRYSR 133
Query: 181 SE-LAGKTLAILGLGRVGREVATRMYAFGMNIIGF-DPFVSADQCAQFHCTKME-LEDIW 351
+ + G+ + ++GLG++G A R AFG + P S + + ++D+
Sbjct: 134 ARGIHGRRVGVVGLGQIGLAFAERAAAFGATVHAVAKPGRSPKTAERADAIGIRFVDDLT 193
Query: 352 PLA---DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
LA D ++LH P +TRN ++AD+L + G I+N RG L+ E + A++
Sbjct: 194 TLARTCDVLSLHVPATSATRNLVDADLLAHVQPGTIILNTSRGELVDEDALIAAME 249
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 103 bits (247), Expect = 2e-21
Identities = 53/174 (30%), Positives = 92/174 (52%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D + A ++G+ V+ P + LS E +M+ L RH+ + L+ G + G
Sbjct: 114 DNVDCERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVG 173
Query: 181 SELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
S + GKT+ ++G G++GR VA + F M ++G+D F D C + + L+++
Sbjct: 174 SSMRGKTVGVVGTGKIGRGVAEILKNGFQMRVLGYDKFEKDDFCGDY----VSLDELLAR 229
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D ++LH PL TR I + + + K+G +IN RG L+ + L SG+
Sbjct: 230 SDVVSLHLPLTPETRGMICVETIAKMKEGTILINTSRGLLVDARAAIDGLYSGR 283
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 103 bits (246), Expect = 3e-21
Identities = 56/173 (32%), Positives = 88/173 (50%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID A +KG+ V N PG NA + +L LML AR++ + L+ G W+ ++ G
Sbjct: 81 DNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWELSM--G 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ K L I+G G +G+ +A R F M ++ + F + + ++L + +
Sbjct: 139 IEIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYGTFQDQTIADRLNVEFVDLNKLLNES 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D + + T L + INA L + KK INV RG L+ E +AL +GK
Sbjct: 199 DIVVVSTTLRKDNYQLINAKTLNEIKKDALFINVSRGALVDEDALYEALTNGK 251
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 103 bits (246), Expect = 3e-21
Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV + + + V N PG + +L L+L AR++ AS + GRW TG
Sbjct: 85 DNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAARNLPAASLDAREGRWQTWSPTG 144
Query: 181 ---SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
EL G TL ++GLG++G VA R AFGM+I+ + A + T++EL+ +
Sbjct: 145 WLGLELRGATLGVVGLGKIGLAVAQRARAFGMDIL-YTRRSDAPAPPELGATRVELDALL 203
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ++LH PL TR+ I+A L + K ++N RG ++ + AL++G+
Sbjct: 204 ARADVVSLHVPLRPDTRHLIDAAALGRMKPSALLVNTARGDVVDQVALQAALEAGQ 259
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 103 bits (246), Expect = 3e-21
Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID A ++ + +INAP N + E LML L + A ++ G+WDR G
Sbjct: 78 DNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKGKWDREGNRG 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS--ADQCAQFHCTKMELEDIWP 354
EL GKT+ I+G G +G +A ++ FG+ +I +D + + +DQ A+ ++ +E+I
Sbjct: 138 YELKGKTVGIIGYGFMGSSLARKLSGFGVQVIAYDKYKTGFSDQYAR----EVSMEEIVK 193
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
L+D ++ H PL TR ++ + L +K + IN RG ++ L AL GK
Sbjct: 194 LSDVLSFHIPLTNETRQLVDEEYLLHFRKPIFFINTARGEIVSTQAVLNALNKGK 248
>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
- Gibberella zeae PH-1
Length = 1068
Score = 102 bits (245), Expect = 4e-21
Identities = 63/180 (35%), Positives = 96/180 (53%), Gaps = 7/180 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV--VPASTALKAGRWDRALY 174
D IDV++ + V V N PG NA + E+T L L +AR V V ++ +
Sbjct: 824 DKIDVEACKRHNVKVCNTPGVNASAVAEMTLCLALTVAREVPDVVIRQKIQGEAIRKETV 883
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMN--IIGFDPFVSADQCA--QFHCTKME-L 339
G L+ K + ++G+G +G+ +A +M+ G+ II FDP+ +Q ++E L
Sbjct: 884 AGMLLSRKIIGVVGMGHIGQAIA-QMFVGGLQAEIIAFDPYFHDNQGPWDTIPYKRVETL 942
Query: 340 EDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ +AD +TLH PL ST+N I A LKQ KK +IN RGG++ E D AL G+
Sbjct: 943 TELLEVADVVTLHVPLTHSTKNMIAAPQLKQMKKTAILINTARGGIVNEEDLADALDKGE 1002
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 102 bits (245), Expect = 4e-21
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 171
D++D A +KG+ V N+P A + E+T L+L ++ + + +++G W
Sbjct: 78 DHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRLAFYDSIVRSGEWIDPSEQR 137
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDI 348
Y G L G TL I G+GR+G VA AFGM ++ D + + D+ + T +E + +
Sbjct: 138 YQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMTVVYNDVYRLPEDKEKELGVTYLEFDQL 197
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD IT+H P + ST + N DV + K +IN RG ++ E ++ALK G+
Sbjct: 198 IKTADVITIHAPALPSTIHKFNKDVFAKMKNRSYLINAARGPIVSEEALIEALKEGE 254
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 102 bits (244), Expect = 6e-21
Identities = 57/170 (33%), Positives = 87/170 (51%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+IDV A KG+ V N P S E LML LAR + ++ G + + G
Sbjct: 77 DHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
ELAGKTL ++G GR+G A FGM+++ +D + ++ ++ ++
Sbjct: 137 IELAGKTLGVIGTGRIGARTALLARCFGMDVVCYDARQN-QILIDAGIKYLDFNELLSVS 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
D+ITLH P + ST + IN D +K KKG +IN RG +++ + LK
Sbjct: 196 DFITLHVPYLPSTHHLINMDNIKLFKKGSFLINTSRGKVVETESVIYGLK 245
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 102 bits (244), Expect = 6e-21
Identities = 61/172 (35%), Positives = 92/172 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+++A +G+ V N P + ELT L L L R V L++G W + + G
Sbjct: 81 DNVDMEAARARGIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRSGVWKKRM--G 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ L GK L I+G+GR+GR VA G+ + DP VS C + C M +E++ A
Sbjct: 139 NLLGGKRLGIVGMGRIGRAVADIFTPLGVQVAFNDP-VSC--CGDYPC--MPVEELLGWA 193
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH + + A+ L++ K+G +INV RGGLI E +AL G
Sbjct: 194 DILSLHCSMTGGECSLFTAEHLRRMKRGSWVINVARGGLIDEQALYEALADG 245
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 101 bits (243), Expect = 8e-21
Identities = 57/173 (32%), Positives = 88/173 (50%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D ID+D+ + GV V+N G NA S E+T LML + R + + +L+A + R
Sbjct: 96 DTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLRAHNCESREDLM 155
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
G EL G+TL ++G+G GR VA A GM +IG DP + A + + + E++
Sbjct: 156 GHELRGRTLGLVGVGHAGRRVAALGRALGMRVIGCDPALDAAELSARGAQAVSFEELLRS 215
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD ++LH P +T ++ + G ++ RGG+ E AL SG
Sbjct: 216 ADIVSLHCPRDATTLRMMDGAAFAAMRPGSIFVSTARGGIHDEGALHAALASG 268
>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
cellular organisms|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 330
Score = 101 bits (242), Expect = 1e-20
Identities = 58/177 (32%), Positives = 90/177 (50%), Gaps = 5/177 (2%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 174
NID+ +A G+ V+N PG NA + E T +L R + AL+ G W LY
Sbjct: 90 NIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALRKGEWRGDLYRAD 149
Query: 175 -TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD-QCAQFHCTKMELEDI 348
TG EL+ T+ ++G G +G +V + AFG +++ DP+V + + L+++
Sbjct: 150 RTGRELSEMTVGVIGYGNIGTKVVRLLRAFGCHVLVSDPYVQLSAEDRNAGVELVALDNL 209
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D +TLH + E TR I D + K GV +IN RG L+ +AL SG+
Sbjct: 210 LARSDVVTLHPRVTEETRGLIGKDAIALMKPGVILINTARGPLVDYDALYEALVSGQ 266
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 101 bits (242), Expect = 1e-20
Identities = 56/173 (32%), Positives = 92/173 (53%), Gaps = 3/173 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 171
D++D+++A ++G+ V + PG + +LT L+L +AR VV + + G W L
Sbjct: 104 DHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPEL 163
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
G +L G TL ++G+GR+G+ VA R AFGM ++ A + LE++
Sbjct: 164 LLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVV-----YHARTPKPLPYPFLSLEELL 218
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
AD ++LHTPL T +N + L K+G +IN RG L+ ++AL+
Sbjct: 219 KEADVVSLHTPLTPETHRLLNRERLFAMKRGAILINTARGALVDTEALVEALR 271
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 101 bits (242), Expect = 1e-20
Identities = 61/174 (35%), Positives = 86/174 (49%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNI++ A +KG+ N PGA S E ++L+ AR + A+ + G W TG
Sbjct: 77 DNINLPRAAEKGIYCTNTPGALEQSVAECAIGMILLAARQFIAAADDCRNGLWQPQ--TG 134
Query: 181 SELAGKTLAILGLGRVGREVAT-RMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
ELAGKTLA++G G +G VA FGM++ G C K D
Sbjct: 135 CELAGKTLAVIGCGAIGSRVAAIAKNGFGMSVTGVIRSAPRPDCPADRFVK-NWSDAVAD 193
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD+++LH P N+++A LKQ K G +IN RG ++ E AL SG+
Sbjct: 194 ADFVSLHIPGSPENLNYVSAGRLKQMKPGSWLINTARGSVVDEAALYDALLSGR 247
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative uncharacterized
protein - Aspergillus terreus (strain NIH 2624)
Length = 743
Score = 101 bits (242), Expect = 1e-20
Identities = 56/175 (32%), Positives = 91/175 (52%), Gaps = 3/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ ID D+ K+G+ ++N PGANA EL TL L +AR + +T + + G
Sbjct: 509 EKIDQDACVKRGIKILNTPGANARDVAELVVTLALSVARGIRSITTRQMSKPVPKETCNG 568
Query: 181 SELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQF--HCTKMELEDIW 351
L KT+ I+G+G +GR VA F +I+ +D + + D Q H ++++
Sbjct: 569 LTLYQKTIGIIGMGNIGRTVAEIFRGGFAADIVAYDAY-TPDNIWQHIPHVRARSIDEVL 627
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD +++H PL + TR+ I D ++ K +IN RGG++ E D +AL G
Sbjct: 628 VRADVLSIHVPLTKDTRDMITYDRIRAMKPDAILINAARGGIVNERDLTRALSEG 682
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 101 bits (241), Expect = 1e-20
Identities = 53/173 (30%), Positives = 95/173 (54%), Gaps = 4/173 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
+NIDVD+A +GV V N P + +L +L+ +RHV+PA ++ G W+
Sbjct: 165 NNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTG 224
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDI 348
+ G E + KTL I+G+GR+G+ A R+ +GMN++ D + ++EL+ +
Sbjct: 225 WLGVEPSDKTLGIVGMGRIGKATAKRLVGGWGMNLLYTSRSDQGDVEKELGGRRVELDTL 284
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
+D++++H L + TRN I+AD + + K ++N RG ++ + + AL
Sbjct: 285 LAESDFVSVHVALTDETRNLIDADAIGKMKSTSVLVNTARGEIVDQDALVDAL 337
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 101 bits (241), Expect = 1e-20
Identities = 61/185 (32%), Positives = 97/185 (52%), Gaps = 12/185 (6%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-STALKAGRWDRALYT 177
+NI ++ A +G V N PG+NA + EL T++L+ R V + A K D +L T
Sbjct: 61 NNIPLEKATSQGTAVFNTPGSNANAVKELIITMLLLSVRPVFASVKWAQKLAGADVSLQT 120
Query: 178 --------GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF--HCT 327
G+EL GK + I+GLG +G VA GM +IG+DP++S ++ Q
Sbjct: 121 EKGKNHFAGTELYGKKIGIIGLGNIGSRVAKACMDLGMKVIGYDPYISVEKAWQLSNDIP 180
Query: 328 KME-LEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQA 504
+ E LE++ +D+IT+H P + RN I D + K ++N R G++ E ++A
Sbjct: 181 RAESLEELLEQSDFITIHIPYTDKNRNIIGEDEINVMKDTAVLLNYSRWGIVDEDAVIKA 240
Query: 505 LKSGK 519
L + K
Sbjct: 241 LDAKK 245
>UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase;
n=10; Bacteria|Rep: Possible phosphoglycerate
dehydrogenase - Clostridium acetobutylicum
Length = 324
Score = 100 bits (240), Expect = 2e-20
Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 7/178 (3%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL----- 171
+D++ A KKG+ V N P + S +++ L+L + HV + ++K G W
Sbjct: 84 VDLEFAKKKGIVVTNIPQYSTSSVVQMSMALILEICGHVGQHNASVKKGDWQNCADFSYL 143
Query: 172 -YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELED 345
Y EL+GKT+ ++G G +G+ + A GM + + P D+ + K + L+
Sbjct: 144 KYPIIELSGKTIGLVGYGSIGKAMQKAAEALGMKVFVYTPH--PDKKYENESMKFVSLDT 201
Query: 346 IWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ AD I+LH PL + + IN +K+ K GV IIN RGGLI E D +ALK K
Sbjct: 202 LFKEADVISLHCPLKDDNKEMINKASIKKMKNGVIIINTARGGLINERDLYEALKENK 259
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 100 bits (240), Expect = 2e-20
Identities = 56/172 (32%), Positives = 95/172 (55%), Gaps = 1/172 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 177
DN+D AG+ GV V P ANA + E T +L L++++ S ++ G + L +
Sbjct: 74 DNVDEKFAGEHGVYVTITPMANASTVAETTIAEILDLSKNLTKISDEMRQGNFAYKLDHM 133
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
G +L+ K + ++G GR+GR+VA + A GM+++ FDPFV + + ++ + +
Sbjct: 134 GFDLSHKKIGVMGYGRIGRQVAEKANALGMDVLIFDPFVKETKIGKL----VDRDTLISQ 189
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
+D ITLH + + T + L+ KK +IN+GRG L+ E + ALK+
Sbjct: 190 SDVITLHLAVTDQTIHGFGKRELEMMKKSASLINLGRGALVDEQALIDALKT 241
>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mycobacterium gilvum
PYR-GCK
Length = 298
Score = 100 bits (240), Expect = 2e-20
Identities = 55/173 (31%), Positives = 89/173 (51%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D++D ++A + GV V N PG + +L LAR + A++ G W + G
Sbjct: 74 DSVDHEAARRHGVTVRNTPGVFGYEVADSAFGYILNLARGYMAVDAAVRRGEWPKV--EG 131
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
L G L I+G G +GRE+A R FG ++ FDPFV A + +EL+++ +
Sbjct: 132 ITLDGSRLGIVGFGAIGREIAKRGAGFGQEVVAFDPFVKASPAG---VSMVELDELLATS 188
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ L PL T + I+AD L + ++NV RG ++ E + ALK+G+
Sbjct: 189 RFVVLACPLTPETFHLIDADRLAGMRSDSFLVNVARGPVVLEAALIDALKAGR 241
>UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53R
protein - Paramecium bursaria Chlorella virus 1 (PBCV-1)
Length = 363
Score = 100 bits (239), Expect = 2e-20
Identities = 56/172 (32%), Positives = 87/172 (50%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D +D++ A + G V P + S EL T M+ L+R++ +K G + G
Sbjct: 107 DRLDIEYAKELGFNVYRVPAYSPRSVAELALTHMMALSRNIQLVLPRVKTGNYTMEGLVG 166
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
E+ KT+ I+G G++ +E + II +D + + D + M L D+ +
Sbjct: 167 REITDKTIGIIGTGKIAQEFIKLVKPMAGRIIAYDVYEN-DIVKEMGVEYMSLPDVIKES 225
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D ++LH PL++ST + IN D LK KK IIN RGGLI + AL+SG
Sbjct: 226 DVLSLHCPLMKSTFHMINEDTLKTMKKTAVIINTARGGLIDTEALIDALESG 277
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 100 bits (239), Expect = 2e-20
Identities = 62/187 (33%), Positives = 93/187 (49%), Gaps = 14/187 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-----------STALK 147
+NI V GV V+N PGANA + EL T +L+ +RH+ PA T
Sbjct: 63 NNIPVRPLTLSGVPVLNTPGANANAVKELVITGILLASRHIYPALDYARHIEGDDETITH 122
Query: 148 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV---SADQCAQF 318
++ ++G EL GKTL I+GLG++G +VA GM IG+DP + SA + +
Sbjct: 123 QVEKNKKRFSGFELPGKTLGIIGLGQIGVKVANAAIRLGMKAIGYDPAITVRSAWELSSE 182
Query: 319 HCTKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFL 498
L D+ +D++T+H PL T + IN + + Q K V ++N R ++
Sbjct: 183 VAQAESLRDVLRNSDFVTVHVPLNTHTHHLINEEAIAQMKDNVVVLNFARAEIVDNQALA 242
Query: 499 QALKSGK 519
QAL K
Sbjct: 243 QALAKNK 249
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 100 bits (239), Expect = 2e-20
Identities = 64/188 (34%), Positives = 100/188 (53%), Gaps = 15/188 (7%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV------PASTALKAGRWD 162
+N++V+ A KKG+ V N PGANA + +L ++ V R++ + TA+ + D
Sbjct: 62 NNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCKSLTAVDPDKVD 121
Query: 163 ------RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 324
++ Y G E+AGK L ++GLG++G +A MN+ GFDP + + Q
Sbjct: 122 SVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDPAPALENIHQLSP 181
Query: 325 TKM---ELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDF 495
L+D AD I+LH PL + TRN +NA+ L + K+G +IN R ++ E
Sbjct: 182 QVRVCRALKDAVSDADVISLHLPLNDRTRNLVNAEFLAKVKRGAILINYSRAPIVDEQAV 241
Query: 496 LQALKSGK 519
L AL SG+
Sbjct: 242 LDALDSGQ 249
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 100 bits (239), Expect = 2e-20
Identities = 66/180 (36%), Positives = 94/180 (52%), Gaps = 11/180 (6%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 174
D ID+ +A K G+ V+N PG NA + EL +ML LAR ++ G L +
Sbjct: 110 DKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDRKIRKGASVTKLDGW 169
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYA--FGMNIIGFDPFV-------SADQCAQFHCT 327
G L GKTL ++G G +G VA +M+A F I+ +DP++ SA A H
Sbjct: 170 KGQMLYGKTLGVIGGGNIGLLVA-KMFAGAFSGKIVLYDPYLKSLDTWHSAIPNASIHKV 228
Query: 328 KMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
E++++ +D +T+H PL ST N I+A K K +IN RGG+I E D QAL
Sbjct: 229 S-EIDELLTTSDIVTIHVPLTPSTENMISAPQFKTMKPTAILINTARGGIINEEDLSQAL 287
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 100 bits (239), Expect = 2e-20
Identities = 55/173 (31%), Positives = 85/173 (49%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D++ A GV V N P S E L L L R V A L+ G +D Y G
Sbjct: 77 DNVDLEEATDHGVIVSNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYYVG 136
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
++L KT+ +LG G +G+ V + F MN++ S ++ ++L+ + +
Sbjct: 137 NQLMSKTIGVLGTGEIGKRVIQIAHGFNMNVLSVTAHPSPERAKALGVKFVDLDTLLSES 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +TLH PL T + I A L + K +IN RG +++E ++ALK K
Sbjct: 197 DIVTLHVPLTPETEHMIGARELAKMKPTAILINTARGKVVEEAALMEALKEKK 249
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 99 bits (238), Expect = 3e-20
Identities = 55/176 (31%), Positives = 87/176 (49%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+D + ++ P A + EL +ML L+R ++ A L+ G W + G
Sbjct: 74 DNVDLDYLRNHDLKLVRIPQPGARAVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRG 133
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELED---IW 351
L K L I+GLG +G + A+GM ++G S ++ AQF + L D +
Sbjct: 134 HLLVNKQLGIVGLGNIGTLLGQMGLAWGMQVLGCVEHPSPERAAQFEAKGLHLTDLNTVL 193
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
ADY+ + PL +T I D L K G ++N+ RGG+I E +AL+ G+
Sbjct: 194 STADYLCVCVPLKTTTSGLIGHDELAMVKPGSFVLNMARGGIIDEAALSEALRQGR 249
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 99 bits (238), Expect = 3e-20
Identities = 56/175 (32%), Positives = 93/175 (53%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
DNID+ A +G+ V P ANA S E T L+L A+++V A L+ G ++ R
Sbjct: 76 DNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKELRQGNYEIRNQMP 135
Query: 178 GSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G ++ GKTL I+G GR+G+ VA + GM I+ + + + + E++++
Sbjct: 136 GIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAYGRGLEIKEVPDYVTIIKEVDELIR 195
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D+I+LH P + + F+++ L K +IN RGG++ E D AL + K
Sbjct: 196 QSDFISLHMPYSKEMQGFMDSTKLSLMKPEAVLINTARGGIVNEDDLYHALINHK 250
>UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridium
botulinum|Rep: D-lactate dehydrogenase - Clostridium
botulinum (strain ATCC 19397 / Type A)
Length = 336
Score = 99 bits (238), Expect = 3e-20
Identities = 60/174 (34%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+NID D+A + G+ V N P + S E T L L L R + A ++ + G
Sbjct: 85 NNIDFDAAKEFGINVANVPAYSPNSVSEFTIGLALSLTRKIPFALKRVELNNFALGGLIG 144
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMN-IIGFDPFVSADQCAQFHCTKMELEDIWPL 357
EL TL ++G GR+G +V FGM +IG+D F + + A+ + L++++
Sbjct: 145 VELRNLTLGVIGTGRIGLKVIEGFSGFGMKKMIGYDIFENEE--AKKYIEYKSLDEVFKE 202
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ITLH PL + + I + + + K GV IIN RG LI ++ LKSGK
Sbjct: 203 ADIITLHAPLTDDNYHMIGKESIAKMKDGVFIINAARGALIDSEALIEGLKSGK 256
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/176 (34%), Positives = 92/176 (52%), Gaps = 3/176 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSA-CELTCTLMLVLARHVVPASTALKAGRW-DRALY 174
D ID++SA KKG V G A E L+L + R V AS +K G+W +RA +
Sbjct: 106 DAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKEGKWHERANF 165
Query: 175 TGSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
G E+ GKT I+G+G +G VA + Y FG +I +DP +S ++ + + LE++
Sbjct: 166 IGYEIKGKTAGIIGIGNIGSRVAEILKYGFGAEVIAYDPNLSKEEIIKREARPVSLEELL 225
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I+L+ L E + ++ K V I+N RG LI ++AL+ GK
Sbjct: 226 RSSDIISLNASLNERNYHMLSYKEFSMMKNNVFIVNTARGELIDTEALIKALREGK 281
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 99.5 bits (237), Expect = 4e-20
Identities = 59/177 (33%), Positives = 93/177 (52%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 171
D+ID+D A +KG+ V N P + EL T+++ AR + AL+ G + D
Sbjct: 81 DHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNVDEYD 140
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDI 348
G + GKTL ILG+GR+G++VA A GM II + + + A+ + ++ +
Sbjct: 141 SQGYTIEGKTLGILGMGRIGQQVARFAKALGMKIIYHNRHQLKPELEAELNARYVDFASL 200
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D+++LH P + T + I+ DV K +INV RG L+ D + ALK GK
Sbjct: 201 VKNSDFLSLHAPATDETYHIIDKDVFNNMKDTSFLINVARGSLVDSDDLVAALKEGK 257
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 99.5 bits (237), Expect = 4e-20
Identities = 57/179 (31%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D ID++ A ++GV V G+NA + E T L+L R + A +++ G+W +YT
Sbjct: 84 DKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILAALRRLALADQSMREGKW---IYTE 140
Query: 181 -----SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA-QFHCTKMELE 342
+L+GKT+ ILG G +GR VA R+ F + II DPF + + + T + +
Sbjct: 141 LRPLCRKLSGKTVGILGFGNIGRNVAQRLQGFDVEIIYHDPFRAPPEVEDRLKATYVSFD 200
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ ++ +TLH P + + INA L + ++G ++N RG ++ E + AL+SG+
Sbjct: 201 ELIKRSNILTLHCPGGAANHHIINASALAKMQRGSVLVNCARGDVVDEEAMVAALQSGQ 259
>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
aurescens (strain TC1)
Length = 329
Score = 99.5 bits (237), Expect = 4e-20
Identities = 58/183 (31%), Positives = 100/183 (54%), Gaps = 11/183 (6%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
+NIDVD+A + G+ V N PG + ++ L+L AR VV + ++ G+ W+
Sbjct: 78 NNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESDRVVRDGKFLGWEPEF 137
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF------VSADQCAQF--HCT 327
G +++G L + G GR+ R VA R FGM + F P VS ++ +F
Sbjct: 138 MLGRDVSGAVLGLAGFGRIARAVARRALGFGMEEL-FSPRPPGDRPVSDEELGEFAGKVR 196
Query: 328 KMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
++ + + +D+++LH PL E TR+ ++ADVL + K +IN RG ++ E+ ++AL
Sbjct: 197 QVPWDSLVERSDFLSLHVPLNEQTRHLVDADVLGRMKSDAILINTARGPVVDESALVEAL 256
Query: 508 KSG 516
++G
Sbjct: 257 RNG 259
>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Pelobacter propionicus (strain DSM 2379)
Length = 318
Score = 99.1 bits (236), Expect = 5e-20
Identities = 64/178 (35%), Positives = 93/178 (52%), Gaps = 6/178 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 171
+NID+ +A +G+GV N P + + +L T ML L+ +V T L+ G D ++L
Sbjct: 80 NNIDIAAARSRGIGVCNVPSYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLDNFQKSL 139
Query: 172 YTGS-ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQCAQFHCTKMELE 342
EL GKTL ++G G +GR V GM II P D +F + LE
Sbjct: 140 QLPHFELNGKTLGVIGFGEIGRRVIAIARTLGMKIIVHSRTPRPELDPDLRF----VSLE 195
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
++ +D+++LH PL ++TR+ INA+ L+ K IIN RG LI E QAL G
Sbjct: 196 ELLATSDFVSLHCPLNDATRHVINAERLEMMKPTAFIINTSRGPLIHEPALSQALTRG 253
>UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=13; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Shewanella sp. (strain ANA-3)
Length = 329
Score = 99.1 bits (236), Expect = 5e-20
Identities = 52/173 (30%), Positives = 88/173 (50%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N+D+ +A + G+ V+N P + S E T LML L R + A + + G
Sbjct: 80 NNVDLVAAKRLGMQVVNVPAYSPESVAEHTVALMLTLNRKIHKAYQRTRDANFSLEGLVG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ GKT+ ++G G++G + FG +I FDP+ + + +L+ I+ +
Sbjct: 140 FNMFGKTVGVIGTGKIGVATIKVLLGFGCKVIAFDPYPN-PAVEALNVEYQDLDTIYANS 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D I+LH PL + +N + + K GV +IN RGGL+ D ++ALK G+
Sbjct: 199 DIISLHCPLTADNHHLLNKESFAKMKPGVMVINTSRGGLLNAFDAMEALKLGQ 251
>UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n=4;
Bordetella|Rep: Putative 2-hydroxyacid dehydrogenase -
Bordetella parapertussis
Length = 322
Score = 98.7 bits (235), Expect = 7e-20
Identities = 54/173 (31%), Positives = 91/173 (52%), Gaps = 2/173 (1%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSAC--ELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
ID+ + G+ V APG+ A EL +L L + + A++ G W +
Sbjct: 84 IDMQACAAGGILVCGAPGSAEAGAATAELAWAHILALFKRLPQEDAAMRRGLWQTGM--P 141
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
LAG+ L +LGLG++G VA AFGM ++ + P ++ ++ AQ T+++ ++ A
Sbjct: 142 QPLAGRRLGVLGLGKLGSAVAQVGRAFGMEVVAWSPNLTDERAAQAGVTRVDKHTLFSTA 201
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D ++LH L ESTR+ ++A L K ++N R GL+ + L AL+ G+
Sbjct: 202 DVVSLHLILGESTRHIVDAAALSAMKPSAYLVNTSRAGLVDQDALLDALRKGR 254
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 98.7 bits (235), Expect = 7e-20
Identities = 57/179 (31%), Positives = 96/179 (53%), Gaps = 9/179 (5%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS---------TALKAG 153
+ I+V+ A + G V+N PG NA + EL +L+ +R ++ AS L+
Sbjct: 61 NTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPIIEASRMVQTLTGPNILEQA 120
Query: 154 RWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM 333
R+ Y G EL GKT+ +LGLG +G +VA Y+ GM+++G+ S + +
Sbjct: 121 ENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDVLGY----SIRDAQLDYVRQA 176
Query: 334 ELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
+LE + +DYI + PL E T+ I+ +++ KK +INVGR ++ + +QAL+
Sbjct: 177 DLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLINVGRSEIVDKYAVMQALE 235
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 98.7 bits (235), Expect = 7e-20
Identities = 57/172 (33%), Positives = 94/172 (54%), Gaps = 2/172 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D ID+ A ++GV V+ P AN S E + ++LA+ + AL+ G W R
Sbjct: 78 DAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIALRTGDWAARNRLI 137
Query: 178 GSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G+EL GK L +LG GR+GR+ A F MN+I +D + ++ E+++
Sbjct: 138 GTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYDVCDYPAVEKELQAKRVSGEEVFE 197
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
+D+I+++ PL+ STR+F+NA +++ K +IN+ RG + E D AL+
Sbjct: 198 QSDFISVNLPLLPSTRHFVNAKLIRLMKPTAFLINMARGPVWNEEDVAGALR 249
>UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia phymatum STM815
Length = 321
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/176 (30%), Positives = 92/176 (52%), Gaps = 4/176 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT- 177
D DVD K+G+ + N P S + +L+L+ AR + + +KAG+W + +
Sbjct: 74 DAFDVDYLNKRGILLTNTPDVLTESTADTAFSLILLTARRLAELAAFVKAGKWTKKIAED 133
Query: 178 --GSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 348
G ++ KTL I+GLGR+G VA R F MN++ D V+ ++ ++ +++
Sbjct: 134 RFGVDVHHKTLGIVGLGRIGTSVARRAALGFQMNVLYVDQGVNEKAEREYGAKRVSFDEL 193
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D++ L PL TRN I+ L+ K+ +IN RG ++ E ++AL+ G
Sbjct: 194 LKTSDFVLLQAPLTPETRNLISTPQLQAMKRSAFLINASRGPIVDEPALVKALQDG 249
>UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2;
Sclerotiniaceae|Rep: Formate dehydrogenase - Sclerotinia
sclerotiorum 1980
Length = 436
Score = 98.7 bits (235), Expect = 7e-20
Identities = 57/179 (31%), Positives = 97/179 (54%), Gaps = 7/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 174
D++D+++A K G+ V G+N +S E +LVL R+ VPA ++AG WD A
Sbjct: 159 DHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILVLVRNFVPAHEQIQAGEWDVAAA 218
Query: 175 TGSE--LAGKTLAILGLGRVGREVATRMYAFGMN-IIGFD-PFVSADQCAQFHCTKM-EL 339
+E L GK + + +GR+G V R+ F ++ FD + + + C ++ +L
Sbjct: 219 AKNEFDLEGKVVGTVAVGRIGERVLRRLKPFDCKELLYFDYQPLKPEIEKEIGCRRVTDL 278
Query: 340 EDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
E++ D +T++ PL E TR N +++ + KKG ++N RG ++ + D ALKSG
Sbjct: 279 EEMLAQCDVVTINCPLHEKTRGLFNKELISKMKKGSWLVNTARGAIVVKEDVADALKSG 337
>UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2;
Firmicutes|Rep: D-lactate dehydrogenase - Clostridium
tetani
Length = 327
Score = 98.3 bits (234), Expect = 9e-20
Identities = 57/173 (32%), Positives = 91/173 (52%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+NID+++A + + V NA + S + L L+L R V+ + A G
Sbjct: 80 NNIDMEAAKEFRIKVSNAT-YSPNSVADFATMLALMLNRRVIETLKRSVGNDYSLAGLMG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL + + ++G GR+G+ V FG II +D + + + + + ++L + A
Sbjct: 139 NELHNQVVGVIGTGRIGQSVVKNFSGFGCKIIAYDLYPNEEM--KKYVEYVDLGTLLSKA 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D IT+HTPL ES + IN + + + K GVKIIN RG LI D ++ LKSGK
Sbjct: 197 DIITIHTPLFESNYHLINKETISKMKDGVKIINTARGELINTFDLIEGLKSGK 249
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 98.3 bits (234), Expect = 9e-20
Identities = 60/175 (34%), Positives = 89/175 (50%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D +D+ +A K GV V+NAP AN+ S EL ML +R+ + + L T
Sbjct: 96 DTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQTMLVDYYKAKLDTP 155
Query: 181 -SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWP 354
SE+A K L ++G+G +G VA F M +IGFDP+ AD T+ + + I+
Sbjct: 156 KSEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPYKTQADMPEGVELTQ-DFDRIFT 214
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D+++LH P T+ F+NA L K +IN RG ++ E D AL + K
Sbjct: 215 DCDFVSLHCPSTPETKGFVNARQLGLMKGSAVLINTARGTIVNEDDLYGALTNRK 269
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 98.3 bits (234), Expect = 9e-20
Identities = 53/167 (31%), Positives = 88/167 (52%), Gaps = 5/167 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA---- 168
D +DV +A ++ + V N PGA + ++ L+L R A L+ G W+R
Sbjct: 56 DTVDVKAATERNIWVCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDI 115
Query: 169 -LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELED 345
+ G+ GKTL I+G+G +G+ +A R A M +I + + + T ++D
Sbjct: 116 LAFWGNNPEGKTLGIIGMGNIGKALAKRAAALDMRVIYYKRTPLPKE-EENGATYKSMDD 174
Query: 346 IWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQE 486
+ +D+I++HTPL ++TR+ + D + KKGV IIN RG +I E
Sbjct: 175 LLAESDFISIHTPLTDATRHILGRDQFAKMKKGVYIINTARGPVIDE 221
>UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Rep:
Ribeye a protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1147
Score = 97.9 bits (233), Expect = 1e-19
Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 8/181 (4%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ +AG+ G+ V N P A + T +L L R A++ G +++
Sbjct: 852 DNIDIKAAGEMGIAVCNIPSAAVEETADSTLCHILNLYRRNTWLYQAMREGTRVQSVEQI 911
Query: 181 SELA-------GKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-E 336
E+A G+TL ++G GR G+ VA R AFG N+I +DP++ ++
Sbjct: 912 REVASGAARIRGETLGLIGFGRSGQAVAVRAKAFGFNVIFYDPYLQDGLERSLGVQRVYT 971
Query: 337 LEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
L+D+ +D ++LH L E + IN +KQ ++G ++N RGGL+ E QALK G
Sbjct: 972 LQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEG 1031
Query: 517 K 519
+
Sbjct: 1032 R 1032
>UniRef50_Q9K1Q1 Cluster: Glycerate dehydrogenase; n=6; cellular
organisms|Rep: Glycerate dehydrogenase - Neisseria
meningitidis serogroup B
Length = 317
Score = 97.9 bits (233), Expect = 1e-19
Identities = 61/179 (34%), Positives = 89/179 (49%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA---L 171
+N+D+ +A GV V N S E LM+ L R++ + AG W+++
Sbjct: 77 NNVDIGAAKAAGVAVCNVRAYGNESVAEHAFMLMIALMRNLPAYQRDVAAGLWEKSPFFC 136
Query: 172 YTGS---ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 342
+ G+ +L GKTLA+ G G +GR +A AFGM ++ F + + E
Sbjct: 137 HYGAPIRDLNGKTLAVFGRGNIGRTLAGYAQAFGMGVV----FAEHKHASAVREGYVSFE 192
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D AD ++LH PL T N I + L+Q K G +IN GRGGL+ E L ALK G+
Sbjct: 193 DAVRAADVLSLHCPLNAQTENMIGENELRQMKPGAVLINCGRGGLVDENALLAALKYGQ 251
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 97.9 bits (233), Expect = 1e-19
Identities = 54/174 (31%), Positives = 88/174 (50%), Gaps = 3/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 171
DNID+ A K GV V N P + EL TLML +AR ++ A++ ++ G+W L
Sbjct: 79 DNIDISLAKKHGVVVTNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYL 138
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
+G ++ G T+ I G+G +G+ A R+ F II + + + T + + +
Sbjct: 139 LSGKDVYGATVGIFGMGDIGKAFARRLQGFDARIIYHNRKRDLNAERDLNATYVTFKSLL 198
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
+D+I PL + T N +A + K IN+GRG ++ E L+ALK+
Sbjct: 199 EQSDFIICTAPLTKETENQFDARAFNKMKNDAVFINIGRGAIVDEEALLEALKN 252
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 97.5 bits (232), Expect = 2e-19
Identities = 53/173 (30%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNI V +A GV V+N P + T LML R + ++K G W A+
Sbjct: 80 DNIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRIPTFDRSVKRGEWKWAVGQP 139
Query: 181 -SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
LAG T+ ++ G++ A ++ F +++I +DP+ + + LE +
Sbjct: 140 IRRLAGSTVGLVAFGKLASRFAAKLRGFDIDVIAYDPYAPEYRMGDLGVESVTLETLLGD 199
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D ++LH PL + TR I+AD L + ++N RGGL+ ET AL SG
Sbjct: 200 SDIVSLHAPLTDETRGMIDADALDRMHDDALLVNTARGGLVDETALYDALISG 252
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 97.1 bits (231), Expect = 2e-19
Identities = 53/173 (30%), Positives = 92/173 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+I++++ K + V N+ G + S ELT L+L L R++VP + ++ G + Y+
Sbjct: 122 DHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQ 180
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+LAGKTL ++G G +G EV AFG N++ ++ + T+ L+++ +
Sbjct: 181 YDLAGKTLGVIGAGDIGTEVIRIGKAFGCNVLVYNRS-EKQHIKELGATQTTLDEVLKNS 239
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +TLH P T+ IN++ L KK +IN RG ++ +AL G+
Sbjct: 240 DIVTLHIPSNNETKGLINSEKLAMMKKDALLINTARGPVVDNKALAEALNKGE 292
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 97.1 bits (231), Expect = 2e-19
Identities = 54/173 (31%), Positives = 88/173 (50%), Gaps = 3/173 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 171
+N+D+D A ++ + V N P A+ S ELT L+L +AR + + W
Sbjct: 79 NNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLF 138
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
+ G E++GKT+ I+GLG +G VA R AF MNI+ P D+ + ++LE +
Sbjct: 139 FRGREVSGKTIGIIGLGEIGSAVARRAKAFDMNILYTGPHQKVDKEREIGAKYVDLETLL 198
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
AD++T++ S + I+ + K +IN RG ++ E +QALK
Sbjct: 199 KNADFVTINAAYNPSLHHQIDKAQFEMMKPTSYLINASRGPIVHEKALVQALK 251
>UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=13;
Staphylococcus|Rep: NAD-dependent formate dehydrogenase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 389
Score = 97.1 bits (231), Expect = 2e-19
Identities = 51/173 (29%), Positives = 87/173 (50%), Gaps = 2/173 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D++D+ +A + +GV+ G+N +S E +L+L R+ K G W+ +
Sbjct: 138 DHVDLQAASEHNIGVVEVTGSNTISVAEHAVMDLLILLRNYEEGHRQAKDGEWNLSKVGN 197
Query: 181 S--ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
EL KT+ I G GR+G+ VA R+ F + I +DP D H T + +++
Sbjct: 198 HVHELQIKTIGIFGFGRIGQLVAERLAPFNVTIQHYDPINQKDN---EHSTFVNFDELVS 254
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
+D +T+H PL T N + DVL + K G ++N RG ++ D ++ L +
Sbjct: 255 TSDAVTIHAPLTPETDNLFDYDVLSRMKVGSYLVNTARGKIVNTNDLVELLNA 307
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 97.1 bits (231), Expect = 2e-19
Identities = 53/173 (30%), Positives = 92/173 (53%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID + +K + + +A N ++ E T L+L L ++V + T +K W R G
Sbjct: 78 DNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALINNIVRSDTEVKDAIWLREENRG 137
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL T+ ++G G +G+E + R+ AFG II +D + C + ++++E + A
Sbjct: 138 YELESLTVGLIGYGNMGKETSKRLAAFGCKIIAYDKYRENYSCK--NAEQVDIEKLKAEA 195
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D I+LH PL + +R +++ K +IN RG +++ D +AL+SGK
Sbjct: 196 DIISLHIPLDDFSRGWVDKTFFDSVAKPFWLINTARGEIVKLKDLNEALQSGK 248
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 97.1 bits (231), Expect = 2e-19
Identities = 61/174 (35%), Positives = 89/174 (51%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D +D ++A +KGV V N PGANA S EL L L +AR + A AL+ G+ R
Sbjct: 74 DPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALREGKTGFRESAR 133
Query: 178 GSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
SEL G+T ++G G GRE + AF M ++ P V + + L +
Sbjct: 134 FSELRGRTALVVGWGASGRETGRMLAQAFDMRLLVHSPRVPRIEGGE---RVASLAEGLA 190
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD ++LHTPL T + ++A + G +IN+ R GL+ E L+A+ SG
Sbjct: 191 AADLVSLHTPLRPETHHMMDARAFAAMRPGAILINMARAGLVDEAALLEAVASG 244
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 97.1 bits (231), Expect = 2e-19
Identities = 64/179 (35%), Positives = 92/179 (51%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
DNIDV +A GV V N PG + + T L+L + R VV L++ R W +
Sbjct: 83 DNIDVAAAHAAGVTVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRM 142
Query: 172 YTGSEL-AGKTLAILGLGRVGREVATRMYAFGMNIIGFDP--FVSADQCAQFHCTKMELE 342
TG ++ AG TL ILG GR+GR VA R AF M ++ AD F T L
Sbjct: 143 LTGLDVSAGATLGILGYGRIGRAVARRARAFDMTVLATSRRRTSGADDDVWFVDTDTLLA 202
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D +D + + TPL TR+ I+A L + K ++N RGG++ E+ + AL++G+
Sbjct: 203 D----SDVVCVLTPLTPETRHLIDAAALDRMKSTAYLVNTARGGVVDESALIDALRAGR 257
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 97.1 bits (231), Expect = 2e-19
Identities = 51/174 (29%), Positives = 90/174 (51%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ +D+D A +GV V N+P AN S EL ++ L+R + S + G W++
Sbjct: 188 NQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVWNKTHVGC 247
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQCAQFHCTKMELEDIWP 354
E+ GKT+ I+G G +G +V A GMN++ +D P ++ +F + D+
Sbjct: 248 YEVRGKTVGIVGYGHIGSQVGVLAEALGMNVVFYDVLPTLAIGNATKF----THINDLLT 303
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D++T+H P + T+ I + ++ KKG +IN RG ++ +AL+ G
Sbjct: 304 FSDFVTIHVPETDVTKGMIGEEQIRLMKKGSYLINASRGTVVDLEALAKALREG 357
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 97.1 bits (231), Expect = 2e-19
Identities = 55/171 (32%), Positives = 95/171 (55%), Gaps = 1/171 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+++ K G+ V N P A+A S E +++L L + +++GRW R +
Sbjct: 73 DNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLSLIKDQRFLDAEIRSGRWPR-ITRS 131
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQCAQFHCTKMELEDIWPL 357
S+L GKT I+G+G +GR +A R+ F + II D +S + ++ T + L+ +
Sbjct: 132 SDLMGKTFGIVGMGSIGRALAARLLPFKVAIIYNDTKRMSEAEEEEYGATFVSLDRLLSD 191
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
+D I++H PL E+TR+ N+ K G IN RG ++ E D ++A++
Sbjct: 192 SDVISVHVPLNETTRHMFNSSRFGLMKDGAIFINTSRGEVVVEKDLIEAIQ 242
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 97.1 bits (231), Expect = 2e-19
Identities = 55/172 (31%), Positives = 86/172 (50%), Gaps = 1/172 (0%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 186
+DV +A K + V N P AN+L+ E T L+L L + + + K+G W + Y +
Sbjct: 93 VDVPAAKKHNIAVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQD 150
Query: 187 LAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLAD 363
++ KT+ I+G+G +GR VA +MY FG I+ + +D + +EL D+ L+D
Sbjct: 151 VSDKTIGIVGMGSIGRLVAKKMYYGFGCKILYYSRTRESDIEQELDAKFVELHDLCRLSD 210
Query: 364 YITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
ITLH P TR+ I+ + +IN R L+ AL S K
Sbjct: 211 VITLHLPYTSETRHIIDEKCFHEMSPDTCLINTARAELVSPIALRDALLSNK 262
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 96.7 bits (230), Expect = 3e-19
Identities = 54/172 (31%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 177
D +DV++ GV V+N G NA S E +ML L++ ++ + L+ R +R
Sbjct: 101 DPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLRRERDVNRNDLV 160
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAF-GMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G+E+ KT+ I+GLG VGR +A GM ++ +DP+++A+ A+ K+EL+++
Sbjct: 161 GNEVEHKTVGIIGLGNVGRRIAALCNGLLGMKVLAYDPYLTAEVMAERGGEKVELDELLR 220
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
AD++++ PL + +RN I+ + I RG + E LQAL+
Sbjct: 221 RADFVSISCPLNKGSRNMISVREFALMQPHAYFITTARGFIHDEDALLQALR 272
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 96.7 bits (230), Expect = 3e-19
Identities = 54/173 (31%), Positives = 91/173 (52%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D++D+D A +KG+ V N P S ELT + L L R V A +K G W + + G
Sbjct: 82 DSVDLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--G 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ + K + ++GLG++G+ A++ AFG +++ FD + +++E + +
Sbjct: 140 NLMYEKKVGLIGLGKIGKLAASQFQAFGCSVMAFDLYPETAWAEANDVEIVDMEKLLAES 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D I+LH P + I A L+ K+G +IN+ R G++ E +ALKS K
Sbjct: 200 DIISLHIP--KPDTELIGAAELESMKEGSFLINIARDGIVNEGALYEALKSNK 250
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 96.7 bits (230), Expect = 3e-19
Identities = 56/173 (32%), Positives = 88/173 (50%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ +D+ +A ++GV V NAP AN S ELT +++L R + A++ G W +
Sbjct: 83 NQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKMFAIQRGEWLKTADGA 142
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPL 357
+E+ K L I+G G +G +++ A GM++ +D A + A + M+ L+DI
Sbjct: 143 NEVRKKKLGIIGYGNIGAQLSVIASALGMHVYYYD---IAPKLAHGNARPMDTLDDILTE 199
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D +TLH P T+N I D + K G +IN RG L+ AL SG
Sbjct: 200 CDVVTLHVPSTPRTKNMIGKDQIALMKHGAFLINQARGDLVDVDALADALNSG 252
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 96.7 bits (230), Expect = 3e-19
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D +DV + +G+ + AN+ S E C L+L + + A A++ G W R
Sbjct: 76 DAVDVAALNARGIALAVCGDANSTSVAEHACMLILAAFKRALRADVAVRRGPWGWRNQLE 135
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWP 354
++ G+ L ILG GR+G+ AT M FGMNI DP++ E L +
Sbjct: 136 SQDIRGRNLLILGFGRIGQHTATMMSGFGMNIRAHDPYLHRHGWPDGGIPAFEDLGEALG 195
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD IT+ P + R I A + K GV I+N RGG++ E + + LKSGK
Sbjct: 196 WADVITVSAP--KGDRPLIGAAEFEAMKPGVVIVNTARGGIVDERELAKHLKSGK 248
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 96.3 bits (229), Expect = 4e-19
Identities = 55/173 (31%), Positives = 81/173 (46%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 177
DNID+ + +G+ V A GAN S E T L+L R ++ ++ G W R L
Sbjct: 78 DNIDMAACAARGISVHPATGANTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRGPLGE 137
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
G E+AG+ L + G G V + VA M I+G DP + T++ ++
Sbjct: 138 GGEIAGRKLGLYGCGAVAQAVARLAKPLSMTILGHDPHLGPGHPLWTEVTRVSDAELLAR 197
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD ++LH PL TR I+A L K G +IN G ++ AL+ G
Sbjct: 198 ADVLSLHLPLTPETRGRIDATALTAMKPGAILINTAHGEIVDARAVCDALRRG 250
>UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98;
Coelomata|Rep: C-terminal-binding protein 2 - Homo
sapiens (Human)
Length = 445
Score = 96.3 bits (229), Expect = 4e-19
Identities = 58/181 (32%), Positives = 94/181 (51%), Gaps = 8/181 (4%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+ +AG+ G+ V N P A + T +L L R AL+ G +++
Sbjct: 109 DNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQI 168
Query: 181 SELA-------GKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-E 336
E+A G+TL ++G GR G+ VA R AFG ++I +DP++ ++
Sbjct: 169 REVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYT 228
Query: 337 LEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
L+D+ +D ++LH L E + IN +KQ ++G ++N RGGL+ E QALK G
Sbjct: 229 LQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEG 288
Query: 517 K 519
+
Sbjct: 289 R 289
>UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella
bronchiseptica|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 333
Score = 95.9 bits (228), Expect = 5e-19
Identities = 55/176 (31%), Positives = 93/176 (52%), Gaps = 4/176 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D IDVD+A + G+ + G+NA EL L+L + R + + ++AG+W +A
Sbjct: 83 DRIDVDAARRLGIPLAITAGSNAGPVAELAVALILGVYRRLCYVNREMRAGQWPKAEMRE 142
Query: 181 S--ELAGKTLAILGLGRVGREVATRMYAFGMNIIGF--DPFVSADQCAQFHCTKMELEDI 348
S ++ KT+ ++G G +GR++A R+ F + I + A+ ++EL ++
Sbjct: 143 SCFQIHRKTIGLVGFGNIGRKLARRLSGFEPDAILYCDQQAAPAEVERALGARRVELPEL 202
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D ++LH P STR I+A L+ KKG +IN RG L+ E +AL+ G
Sbjct: 203 LAASDIVSLHLPCTASTRRLIDAAALQHMKKGAVLINTARGELVDEAALAEALQRG 258
>UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=15;
Campylobacterales|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Campylobacter jejuni
(strain RM1221)
Length = 311
Score = 95.9 bits (228), Expect = 5e-19
Identities = 59/175 (33%), Positives = 92/175 (52%), Gaps = 6/175 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 177
+NID++ A +KG+ V NA G + +S + T M V K G+W + ++T
Sbjct: 75 NNIDIEYAKEKGIIVKNAAGYSTMSVVQHTFAFMFAFLNQVPYYDKWSKEGKWCESPIFT 134
Query: 178 G-----SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 342
+ L+GK I+GLG +G+EVA AFG I + A++ A F +EL+
Sbjct: 135 DYSRILNTLSGKKHGIIGLGTIGKEVAKISKAFGAEIYYYSTS-GANKNADF--VHLELK 191
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
D+ D I++H PL E T+N + + LK K +INVGRGG++ E D + +
Sbjct: 192 DLLKTCDIISIHAPLNEKTKNLLAFEELKLLKDNAILINVGRGGIVNENDLAKII 246
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 95.9 bits (228), Expect = 5e-19
Identities = 58/176 (32%), Positives = 89/176 (50%), Gaps = 4/176 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 171
D+IDV A +G+ V P + +LT LML L R V ++AGRW +
Sbjct: 113 DHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYGAD 172
Query: 172 -YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 348
Y G+++ GKTL ILG+GR+G VA R AFGM +I + S T++ L +
Sbjct: 173 DYLGTDVGGKTLGILGMGRIGSRVAKRAAAFGMKVI----YHSRSSTGP--GTRVTLGRL 226
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D +++H P T ++ L++ K+ +IN RG ++ E D AL+ G
Sbjct: 227 LERSDVLSIHVPHTPDTHEMMDMSRLRKMKRSAYLINTSRGRVVHEKDLAAALRQG 282
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 95.5 bits (227), Expect = 7e-19
Identities = 54/174 (31%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
+NID+ +A K+ + V N P +A++ E T L++ LA +V ++ W
Sbjct: 79 NNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLF 138
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDI 348
+ G L GKTL ILGLG++G+ VA R++AF M I+ + + Q T + +++
Sbjct: 139 FLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMPILYSQHHRLPISRETQLGATFVSQDEL 198
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
AD +TLH PL T + I+ + K +IN RG ++ E + AL+
Sbjct: 199 LQRADIVTLHLPLTTQTTHLIDNAAFSKMKSTALLINAARGPIVDEQALVTALQ 252
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 95.5 bits (227), Expect = 7e-19
Identities = 54/174 (31%), Positives = 89/174 (51%), Gaps = 3/174 (1%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG-S 183
ID+ +A + G+ V+N PGANA S EL + + L + VP A++ G W+ G
Sbjct: 81 IDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVRQGNWNIRYEAGLR 140
Query: 184 ELAGKTLAILGLGRVGREVAT-RMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPL 357
EL+G +L I+G G++GR +A + FGM + + P V+ A C + + L +
Sbjct: 141 ELSGMSLGIVGFGQIGRALAAMAIGGFGMRVHVYSPSVAPQDIAAAGCQRADSLPALARE 200
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ++LH P ++ +L K G +IN R L+ E + L++G+
Sbjct: 201 ADIVSLHRPARPGAGPLVDDALLLAMKPGALLINTARADLVDEAALARHLEAGR 254
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 95.5 bits (227), Expect = 7e-19
Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 168
D I V A G+ V+ P AN S E LMLV AR V A A + G W ++
Sbjct: 74 DKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAATRKGHWGFKYEQP 133
Query: 169 LYTGSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKME-LE 342
+Y+ L GKTL ++GLGR GR + A M + + P + A + +++ L+
Sbjct: 134 MYS---LYGKTLGVIGLGRTGRLLCEMAAPALNMQALVWSPSLPAGEALPPGARRVDTLQ 190
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ AD ++LH PL TR+ ++A L K G +IN RGGLI E AL+ G+
Sbjct: 191 ELLREADVVSLHRPLRPDTRHTLDAATLACMKPGAIVINTSRGGLIDEAALADALREGR 249
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 95.5 bits (227), Expect = 7e-19
Identities = 57/172 (33%), Positives = 85/172 (49%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D++D+ +A + GV V N PG A S E T L+ +AR + A + G W+R
Sbjct: 83 DHVDLAAAARHGVTVANTPGVAARSIAEHTLALLFAVARQIPHMDAATRRGAWERG--QS 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL GKT ++G G VGR A A GM ++ + SA +F LED++ +
Sbjct: 141 MELYGKTCGVIGYGAVGRHFARLATAIGMRVMQWTLHPSAYPDVEF----ASLEDLYRAS 196
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D I++H L T++FI A K ++N RG ++ E L AL +G
Sbjct: 197 DVISVHLRLSPDTQDFIAAPQFALMKSEAILLNTARGAIVSEPALLDALIAG 248
>UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 327
Score = 95.5 bits (227), Expect = 7e-19
Identities = 56/172 (32%), Positives = 90/172 (52%), Gaps = 3/172 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--WDRALY 174
DN D+ + + GV V P EL L + R+V+ A +AG W ALY
Sbjct: 80 DNFDLRACAQAGVSVTFVPDLLTEPTAELAIGLAIAAGRNVLQGDAATRAGYSGWRPALY 139
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGM-NIIGFDPFVSADQCAQFHCTKMELEDIW 351
G+ L G +++GLG+VG+ + R+ FG ++G DP V DQ + L++
Sbjct: 140 -GTGLHGSVASVIGLGKVGQAILARLAGFGCARLLGVDPSVRLDQVEL-----VTLDEAV 193
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
+DY+ L PL+ TR+ +++ +L+ KKG ++NVGRG ++ E + AL
Sbjct: 194 STSDYVFLAVPLVSDTRHLVDSRMLQLSKKGQILVNVGRGSVVDERAVVDAL 245
>UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep:
AFR675Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 353
Score = 95.5 bits (227), Expect = 7e-19
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 4/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D ID +S K+ + V N PG + L+L R+ L+ GRW A G
Sbjct: 93 DQIDPESFTKRQIQVANVPGLVNAPTADTHVFLLLAALRNFCHGQLLLRQGRWPDAPVAG 152
Query: 181 SEL----AGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 348
+ AGKT+ +LG+G +GR V R+ FG I + + C + E++
Sbjct: 153 TPFGHDPAGKTVGVLGMGGIGRAVVQRLRPFGFERIIYHNRNRLSSELECSCEYVSFEEL 212
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D ++++ PL +TR+ ++AD + + K GV ++N RG + E + AL+SGK
Sbjct: 213 LAQSDILSVNVPLSSATRHMLDADAIARMKDGVLVVNTARGPIFDEQALIAALQSGK 269
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 95.5 bits (227), Expect = 7e-19
Identities = 57/173 (32%), Positives = 89/173 (51%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID+ + +KG+ V + P A + ++ LM+ R +AL+AG+W G
Sbjct: 88 DNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIGALRQAYIPLSALRAGQWQGKTTLG 147
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ GK L ILG+G +GRE+A R AFGM I + + + + + +++ A
Sbjct: 148 HDPQGKVLGILGMGGIGREMANRARAFGMKIQYHNRSRLSPE-LEGDAQYVSFDELLANA 206
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D ++L+ L TR+ I ++ K GV I+N RG LI E + AL SGK
Sbjct: 207 DVLSLNLALNAKTRHIIGEKEFQKMKDGVVIVNTARGALIDEKALVAALDSGK 259
>UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 381
Score = 95.1 bits (226), Expect = 9e-19
Identities = 57/179 (31%), Positives = 91/179 (50%), Gaps = 7/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
++I+V A + V N NA + LML + R++ + ++ G+W Y
Sbjct: 132 EHINVKEASNHNIPVFNVI-RNAEPVADFALGLMLDITRNITLSDKFIRNGQWMHEYYNT 190
Query: 181 SELA---GKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF---HCTKME-L 339
++ G + ++G+G VG +A R+ A G++II +D FVS ++ AQ K+E +
Sbjct: 191 GQIKLFNGHLVGLVGIGNVGAAIARRLNALGVSIIAYDSFVSEERLAQQGLGFIKKVETM 250
Query: 340 EDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
ED++ AD ++LH L T IN D K KK IN RGGLI E + +L+ G
Sbjct: 251 EDVFKKADIVSLHLRLTPETEGIINEDYFKLMKKTAYFINTARGGLIDEDALITSLQKG 309
>UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1;
Flavobacteriales bacterium HTCC2170|Rep: D-lactate
dehydrogenase - Flavobacteriales bacterium HTCC2170
Length = 335
Score = 95.1 bits (226), Expect = 9e-19
Identities = 46/170 (27%), Positives = 87/170 (51%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+NI + +A + G+ V NAP + + EL L++ + R ++ A + A +D+ G
Sbjct: 79 NNIQIKAAKRFGLKVANAPDYSPNAIAELAVALLMTINRKIIVADKQVHAHNFDQKNLLG 138
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+L KT+ ++G+GR+G + M+ FG NI+ D + D ++ LE+++ +
Sbjct: 139 CDLVHKTVGVIGVGRIGSVMVKIMHGFGCNILAHDLQPNGDLVEKYQVKYTSLEELYAQS 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
D I+LH PL T ++ + K V ++N RG ++ ++ LK
Sbjct: 199 DIISLHVPLTHETHYMVSENAFNLMKPTVVLLNTARGAVVDTKTLIKVLK 248
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 95.1 bits (226), Expect = 9e-19
Identities = 64/191 (33%), Positives = 96/191 (50%), Gaps = 22/191 (11%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-----------A 150
NIDV++A ++G+ V+ PG N+ +A ELT LML LARH+ A +ALK A
Sbjct: 79 NIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALKQRQFTATTPGNA 138
Query: 151 GR-----WDRA------LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS 297
G WD ++ G EL KTL I+G G +G+ V AFGM ++ DP+VS
Sbjct: 139 GLKTDVVWDVTKDSPYEVFKGVELRNKTLGIVGYGSIGQRVGRIARAFGMQLLVADPYVS 198
Query: 298 ADQCAQFHCTKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGL 477
+ + K LE ++ +D++TLH + T I+ + K IN R +
Sbjct: 199 EVELDEPGIHKTTLERLFSQSDFVTLHVKVTPQTVGLIDTRLFSLMKPEAYFINTSRAAV 258
Query: 478 IQETDFLQALK 510
+ E + AL+
Sbjct: 259 VVEQHLVDALR 269
>UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified
Gammaproteobacteria|Rep: Glyoxylate reductase - marine
gamma proteobacterium HTCC2143
Length = 326
Score = 95.1 bits (226), Expect = 9e-19
Identities = 54/178 (30%), Positives = 92/178 (51%), Gaps = 5/178 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT- 177
D++DV + +G+ + + PG + +L L+L AR + ++ G W A ++
Sbjct: 78 DHVDVGTLTARGIPLGHTPGVLVDATADLAFGLLLAAARRIPQGDRHVRTGGWQGASWSP 137
Query: 178 ----GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELED 345
G +AGKTL I+GLG +G+ +A R F M +I + S + A + LE
Sbjct: 138 KAFLGCSVAGKTLGIIGLGDIGQALARRAAGFDMPVIAWSR--SGREVAGVRT--LSLEQ 193
Query: 346 IWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ +D+++++ L E TR I+A L + K G ++N RGG++ E QALK G+
Sbjct: 194 VLDQSDFVSINVALTEETRGLIDAAALSKMKPGAILVNTARGGIVDERALAQALKEGR 251
>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
Trichocomaceae|Rep: Contig An11c0250, complete genome -
Aspergillus niger
Length = 336
Score = 95.1 bits (226), Expect = 9e-19
Identities = 58/174 (33%), Positives = 94/174 (54%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D ID ++ K+G+ V NAP + +L L+L R++ PA +L AG + + + G
Sbjct: 91 DPIDTEACAKRGIIVTNAPDPVTDATADLAVLLLLGALRNLNPAIRSLYAGTFKQGVGFG 150
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPL 357
+ GKTL ILG+GR+GR V R FG+ + + +SAD A + E +
Sbjct: 151 HDPQGKTLGILGMGRIGRAVKQRCEPFGIKTVYNNRRPLSADLSA--GAEYVSFEKLLTE 208
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I+++ PL +T++ I A + + K G+ IIN RG +I E AL++G+
Sbjct: 209 SDIISINVPLNANTKHLIGAAEIAKMKPGIVIINTARGAIIDEAAMADALETGQ 262
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 94.7 bits (225), Expect = 1e-18
Identities = 55/158 (34%), Positives = 76/158 (48%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 186
+D+ +A G+ V NAP +N S EL ++L R V S AG W + E
Sbjct: 102 VDLPAAAHHGIPVFNAPFSNTRSVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFE 161
Query: 187 LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADY 366
GKT+AI+G G +G +V A GM ++ +D V A L + LAD
Sbjct: 162 ARGKTIAIVGYGNIGAQVGVLAEALGMRVVYYD--VQAKLSLGSAQPARSLGEAIALADV 219
Query: 367 ITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLI 480
+TLH P ST N I+A VL Q K +IN RG ++
Sbjct: 220 VTLHVPAHASTHNMIDASVLAQFKSNAILINASRGTVV 257
>UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Gammaproteobacteria|Rep: 2-hydroxyacid dehydrogenase -
Idiomarina loihiensis
Length = 311
Score = 94.7 bits (225), Expect = 1e-18
Identities = 65/180 (36%), Positives = 90/180 (50%), Gaps = 7/180 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA---- 168
+NID+ +A K + V N S + T +ML LA + AG W +
Sbjct: 77 NNIDLAAAEKLNIPVRNVEAYGTQSVVQHTLMMMLSLATKQPVMQKRVAAGDWQSSSMFC 136
Query: 169 LYTGS--ELAGKTLAILGLGRVGREVATRMYAFGMNI-IGFDPFVSADQCAQFHCTKMEL 339
L S +LAGK L I+G G +G+EV T A GM++ P D + L
Sbjct: 137 LLDPSIIQLAGKKLVIVGSGELGQEVKTMAEALGMHVEFSARPGKKDDP-------RPSL 189
Query: 340 EDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ P AD I+ H PL T+N +NAD L+ CKK IIN RGG+I E D +AL++GK
Sbjct: 190 NELLPSADVISFHCPLTNDTKNLLNADNLELCKKDALIINNARGGVINEQDVTEALRAGK 249
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 94.7 bits (225), Expect = 1e-18
Identities = 55/178 (30%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 171
DNID+++A V V + PG + + L+L ARHV A ++ GR W+
Sbjct: 80 DNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTH 139
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA--QFHCTKMELED 345
G ELA KT+ I+G+GR+G VA R FGM +I + A+ Q + L +
Sbjct: 140 LMGMELARKTIGIVGMGRIGTAVARRALGFGMEVI-YHNRTRANPTVERQVSARHVGLGE 198
Query: 346 IWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ +D ++LH P + + + ++A + K ++N RG ++ E + ALKSG+
Sbjct: 199 LLTTSDVVSLHCPHNDESHHLLDAAAFSKMKASALLVNTARGPVVDEAALVDALKSGE 256
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 94.7 bits (225), Expect = 1e-18
Identities = 56/172 (32%), Positives = 91/172 (52%), Gaps = 3/172 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 177
D ID+ A K GV V+N PG + + E T ++L LA+ + + +K G + R
Sbjct: 90 DAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQ 149
Query: 178 GSELAGKTLAILGLGRVGREVATR-MYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIW 351
+L GKTL I+GLGR+G VA++ AF M ++ +DP+V Q T +E L+ +
Sbjct: 150 PMQLEGKTLGIVGLGRIGSAVASKCSAAFQMRVLAYDPYVLPSQAEAVGGTLVENLDYLL 209
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQAL 507
+D+++LH L + T + K+ K +IN RG ++ E D + A+
Sbjct: 210 AESDFVSLHPELTDETYEMFALEAFKKMKPTAFLINTSRGKIVCEQDLVVAI 261
>UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27;
Lactobacillales|Rep: D-lactate dehydrogenase -
Lactobacillus plantarum
Length = 332
Score = 94.7 bits (225), Expect = 1e-18
Identities = 53/173 (30%), Positives = 87/173 (50%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+DV + +G+ + N P + + EL+ T ++ L R + L + A
Sbjct: 81 DNLDVPTVKARGLNISNVPAYSPNAIAELSVTQLMQLLRQTPLFNKKLAKQDFRWAPDIA 140
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL T+ ++G GR+GR FG +IG+D + +A+ + L++++ A
Sbjct: 141 KELNTMTVGVIGTGRIGRAAIDIFKGFGAKVIGYDVYRNAELEKEGMYVDT-LDELYAQA 199
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D ITLH P ++ + +NAD + K G I+N RG LI D ++AL SGK
Sbjct: 200 DVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGK 252
>UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellular
organisms|Rep: D-lactate dehydrogenase - Escherichia
coli (strain K12)
Length = 329
Score = 94.7 bits (225), Expect = 1e-18
Identities = 50/173 (28%), Positives = 88/173 (50%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N+D+D+A + G+ V+ P + + E +M+ L R + A + + TG
Sbjct: 80 NNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ GKT ++G G++G + + FGM ++ FDP+ SA + ++L ++ +
Sbjct: 140 FTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSA-AALELGVEYVDLPTLFSES 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D I+LH PL + +N +Q K GV I+N RG LI ++ALK+ K
Sbjct: 199 DVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQK 251
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 94.3 bits (224), Expect = 2e-18
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 177
D +DV + ++ V ++ A AN+ S E +ML LA+ + +K G+W DR
Sbjct: 84 DAVDVPALSRRKVPLMVAGSANSPSVAEQALFMMLTLAKRAQEMHSCVKDGKWADRLGML 143
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDIWP 354
+L GKT+ I+G GR+G A R A M + +DP+ A + A + +L+ P
Sbjct: 144 PFDLYGKTVLIIGFGRIGTRTAKRCLAMEMRVQVYDPYKPAAEIKAAGYEPVADLDAALP 203
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD++T+H P T +A + + K +IN RGG+++E AL SGK
Sbjct: 204 HADFVTIHCPKTPETVGLFDAARIGRMKPKSYLINTARGGIVKEAALYDALTSGK 258
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 94.3 bits (224), Expect = 2e-18
Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 3/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 171
D++DV +A +G+ V N P + L+L R +V +++GRW AL
Sbjct: 124 DSVDVKAATARGIPVTNIPDTFIEEVADHAMMLLLAGFRRLVEQDRMVRSGRWAEGRPAL 183
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
L G+TL + GRV R VA R FG+ ++ +DPF+ L ++
Sbjct: 184 LKIPRLMGQTLGFISFGRVARAVAKRAAPFGLRMMAYDPFIQETLMYDHGVIPATLNEVL 243
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+D++++H P + + +Q KKG IN GRG + E ++AL+ G
Sbjct: 244 SQSDFVSMHAPARPEVHHMLTEKHFRQMKKGSIFINTGRGATVDEESLIKALQEG 298
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 94.3 bits (224), Expect = 2e-18
Identities = 51/174 (29%), Positives = 91/174 (52%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+ +D+D A +G+ V N+P +N+ S EL ++ LAR + S L G W++
Sbjct: 134 NQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARC 193
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQCAQFHCTKMELEDIWPL 357
E+ GKTL I+G G +G +++ A G++++ +D + A A+ T L+++
Sbjct: 194 WEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTARQVST---LDELLNK 250
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D++TLH P T ++A K G +IN RG ++ +QA+K+ K
Sbjct: 251 SDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANK 304
>UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n=2;
Lactobacillus|Rep: D-2-hydroxyisocaproate dehydrogenase
- Lactobacillus paracasei
Length = 333
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/175 (32%), Positives = 88/175 (50%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 177
DNID+ + + G+ + N P + + E T L L R++ L+AG +++A +
Sbjct: 80 DNIDMTAMKQYGIRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQAGDYEKAGTFI 139
Query: 178 GSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G EL +T+ ++G G +G +VA +++ FG +I +DP+ F + LED++
Sbjct: 140 GKELGQQTVGVMGTGHIG-QVAIKLFKGFGAKVIAYDPYPMKGDHPDFDY--VSLEDLFK 196
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I LH P IE + IN K G +IN R LI L LKSGK
Sbjct: 197 QSDVIDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGK 251
>UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Pseudomonas aeruginosa
Length = 323
Score = 93.5 bits (222), Expect = 3e-18
Identities = 60/179 (33%), Positives = 90/179 (50%), Gaps = 7/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 171
+NID+ +A ++G+ V N G S + T L+L LA + A+++GRW ++
Sbjct: 82 NNIDLAAARERGIVVANCHGYGTPSVAQHTLALLLALATRLPDYQQAVRSGRWQQSSQFC 141
Query: 172 ---YTGSELAGKTLAILGLGRVGREVATRMYAFGMNII-GFDPFVSADQCAQFHCTKMEL 339
+ EL GKTL +LG G +G VA AFGM ++ G P A ++ L
Sbjct: 142 LLDFPIVELEGKTLGLLGHGELGGAVARLAEAFGMRVLLGQLPGRPA------RADRLPL 195
Query: 340 EDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
++ P D +TLH PL E TR + + L K G ++N RGGL+ E AL+ G
Sbjct: 196 GELLPRVDALTLHCPLTEDTRGMLGSAELALMKPGAFLVNTARGGLVDEQALADALRGG 254
>UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC
14580|Rep: YoaD - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 206
Score = 93.5 bits (222), Expect = 3e-18
Identities = 46/138 (33%), Positives = 81/138 (58%)
Frame = +1
Query: 97 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 276
L+L AR + ++ A+KAG W A+ G EL GKTL ++G G +G++VA R F MN++
Sbjct: 5 LLLSGARSIPQSNAAVKAGLWQAAM--GYELDGKTLGLIGFGEIGKKVARRAAGFNMNVL 62
Query: 277 GFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKII 456
+ + + + + EL+D+ +D++ + T L +T + IN + L + KK +I
Sbjct: 63 AYGTYKDYNAAKRLNVRFAELDDLLEKSDFVCISTSLRPATYHLINQEKLAKMKKTAYLI 122
Query: 457 NVGRGGLIQETDFLQALK 510
N+ RG ++ E+ +QAL+
Sbjct: 123 NIARGEVVDESALIQALE 140
>UniRef50_Q82W00 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=7; Bacteria|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Nitrosomonas europaea
Length = 330
Score = 93.1 bits (221), Expect = 4e-18
Identities = 51/173 (29%), Positives = 86/173 (49%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N+D+ +A + V+ P + + E T +++ L R A ++ + G
Sbjct: 80 NNVDIKAAHACNIRVVRVPAYSPHAVAEHTLAMIMTLNRKTHKAYNRVREQNFSLNGLLG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+L KT+ ++G G +G M+ G NI+ DP V + + + + +++
Sbjct: 140 FDLHKKTVGVIGTGHIGEVFCRIMHGLGCNILACDP-VKKLEIEKMGIPYVPMNELFSRC 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D ++LH PL E TR I++ V+ Q K GV +IN GRGGLI + LKSGK
Sbjct: 199 DILSLHCPLNEETRYLIDSSVIAQMKTGVMLINTGRGGLIDTKAVIAGLKSGK 251
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 93.1 bits (221), Expect = 4e-18
Identities = 52/175 (29%), Positives = 89/175 (50%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--WDRALY 174
DNI V+SA K GV V N PGANA++ EL TL+L + R V A+ +++ G A
Sbjct: 77 DNIPVESATKHGVWVTNTPGANAIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASL 136
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
G L+GK + ++G G++ + + ++ FG +++ + QF + + +
Sbjct: 137 MGHNLSGKIIGLIGYGQIAQNLEKILHGFGAHVLVYSRTKRETLYGQF----VSYDTLLA 192
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I+LH P T +N + + K +IN R L+ E ++A+ +GK
Sbjct: 193 QSDIISLHIPATPETSGILNHEAFSKMKTNAILINTARAALVDEEALVEAINTGK 247
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 93.1 bits (221), Expect = 4e-18
Identities = 51/174 (29%), Positives = 90/174 (51%), Gaps = 3/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 171
+N ++D+A K+GV + N PG + L+L A+ + + ++ G+W
Sbjct: 81 NNFNLDAATKRGVIMTNTPGVLDKATATHAWALLLATAKRISESERYVREGKWKGWSPMT 140
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIW 351
+ G ++ GKTL I GLGR+G A + AF M +I + + D T ++ E +
Sbjct: 141 FIGQDVDGKTLGIAGLGRIGTMFARKAAAFDMKVIYTNEQRNFDFEKDHGATFVDKETLL 200
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKS 513
+D++++H PL T+ +I A L Q K +IN RG L+ E + ++AL++
Sbjct: 201 KESDFLSIHLPLTPETKYYIGAKELSQMKPSAILINAARGPLVNEKELVEALRN 254
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 93.1 bits (221), Expect = 4e-18
Identities = 55/175 (31%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--ALY 174
D +DV++A + GV V N P E+T LML LA V + ++ GRW+ A+
Sbjct: 79 DAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYVRDGRWETEGAMP 138
Query: 175 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMEL-EDIW 351
+EL G T+ I+GLGR+G+ +A AF M ++ A Q Q++ + + D+
Sbjct: 139 LTAELTGATVGIIGLGRIGKAIARLAQAFSMRVVYHGRSEQAHQPYQYYADPVAMARDV- 197
Query: 352 PLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D++ + P TR ++A+VL +++NV RG L+ E + AL G
Sbjct: 198 ---DWLVVIAPSTPQTRGIVSAEVLHALGSEGRLVNVARGDLVDEQALIDALSGG 249
>UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermofilum pendens Hrk
5|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermofilum pendens (strain Hrk 5)
Length = 320
Score = 93.1 bits (221), Expect = 4e-18
Identities = 56/174 (32%), Positives = 81/174 (46%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D++ ++GV V + G NA + E L+L LA+ VV +K G W
Sbjct: 72 DNLDLEYLFERGVKVATSKGCNARAVAEHAFALILALAKRVVEQDGEVKRGLWRSFTEEN 131
Query: 181 --SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 354
++L G T+ I+G G +GREVA AF M ++ D A L +
Sbjct: 132 FLADLDGSTVTIVGYGNIGREVARIAKAFNMRVLAVKKNPEKDSLADEVYPVERLAEALS 191
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
AD++ L PL T I LK KK ++NVGRG ++ E +AL G
Sbjct: 192 QADFVVLALPLTRETYRLIGEKELKSMKKTAYLVNVGRGAVVDEEALYRALSEG 245
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 92.7 bits (220), Expect = 5e-18
Identities = 54/173 (31%), Positives = 86/173 (49%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DN+D+D+A + G+ V N PG N + EL LML AR + + G W R G
Sbjct: 82 DNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDDGGWPRE--AG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+EL GK+L ++G G G+ +A A GM ++ ++Q + + + A
Sbjct: 140 TELRGKSLGVIGYGPSGKAIAALGVALGMRVLVSTAHPDSEQSSGIEFA--DFDTTIKAA 197
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
DY++LH+ + I+A L K +IN RG L+ E ++ALK+G+
Sbjct: 198 DYLSLHSRAGKGD-PIIDAASLSAMKNSAILINTARGSLVDEAALVEALKTGE 249
>UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Paracoccus
pantotrophus|Rep: Putative D-isomer specific
2-hydroxyacid dehydrogenase family protein - Paracoccus
pantotrophus (Thiosphaera pantotropha)
Length = 338
Score = 92.7 bits (220), Expect = 5e-18
Identities = 56/172 (32%), Positives = 91/172 (52%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 183
+ID+ + + G+ V A A + ELT LM+ L R + +L+AG W + G
Sbjct: 83 SIDLAACDRLGITVC-ATDALHQTTVELTVWLMIALMRGLPRECASLRAGGWQVGV--GR 139
Query: 184 ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLAD 363
L GKTL ++GLG +G VA GM++I + P ++ ++ A+ + E+++ AD
Sbjct: 140 SLGGKTLGVVGLGNMGIPVAKICKIMGMDVIAWSPNLTQERAAEHGVRAVSKEELFAQAD 199
Query: 364 YITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+TLH P I +T + ++A L K I+N R LI + L AL+SG+
Sbjct: 200 VVTLHMPHINATEHLVSAAELALMKPTAFIVNTARPKLIDQEALLDALQSGR 251
>UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 315
Score = 92.7 bits (220), Expect = 5e-18
Identities = 56/173 (32%), Positives = 91/173 (52%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 177
D +DV +A ++ + V + PG +L LML +AR + A +++GRW +
Sbjct: 78 DGVDVTAALERNIRVTHTPGVLNDDVADLAIGLMLSVARRIPQADQYVRSGRWPEGPMPL 137
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
+++G+ L I+GLGR+G+ +ATR AFGM++ A+ ++ + L
Sbjct: 138 ARKVSGERLGIVGLGRIGQAIATRAEAFGMSVAYTARSRKAELPYAYYPSAQALA---AE 194
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
D++ L TP TR INADVLK +INV RG ++ E ++AL+ G
Sbjct: 195 VDFLVLITPGGAGTRKLINADVLKALGPQGYLINVARGSVVDEAALVEALQQG 247
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 92.7 bits (220), Expect = 5e-18
Identities = 56/175 (32%), Positives = 92/175 (52%), Gaps = 2/175 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA-LKAGRWDRALYT 177
DN+ + ++G+G++ A GANA+ EL+ LML RH +PA TA ++AG W R+
Sbjct: 82 DNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAALRH-IPAETAGIRAGGWPRS--R 138
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWP 354
G E+A +T+ I+G G +G+ VA + A ++I DPF + + F L++++
Sbjct: 139 GREIAERTVGIIGCGAIGKRVARAVSAMRASVIACDPFRPNVEVYGPFKWA--SLDEVFA 196
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
AD ++LH P + ++A L +IN R L+ E AL G+
Sbjct: 197 GADIVSLHCPAPADGKPIVDAPRLATVPPHAILINTARATLVDEDAVRAALDEGR 251
>UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp.
SK209-2-6|Rep: Dehydrogenase - Roseobacter sp. SK209-2-6
Length = 343
Score = 92.7 bits (220), Expect = 5e-18
Identities = 49/173 (28%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 177
D +DV++A KG+ V N + L L LAR + A AG W ++
Sbjct: 90 DIVDVNAATAKGILVTNVQNYCTEEVADHAIALWLALARKLPDYDRATHAGLWQWQSGQP 149
Query: 178 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 357
L G+T+ ++ LG++G+ +A R AFG+N+I +DPF+ + A+ + ++
Sbjct: 150 VHRLRGRTMGVVSLGKIGQAIAARARAFGVNVIAYDPFLPGEAAAKLGVELVGKPELLAR 209
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+DYI + P+ T +F++ K G ++N GRG + +AL G
Sbjct: 210 SDYILMQAPMTPDTHHFLSDAEFAAMKPGAILVNTGRGPTVDNKALFRALTEG 262
>UniRef50_Q22CX9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain containing protein;
n=2; Oligohymenophorea|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain
containing protein - Tetrahymena thermophila SB210
Length = 359
Score = 92.7 bits (220), Expect = 5e-18
Identities = 52/173 (30%), Positives = 87/173 (50%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N D++ A K + V+ P + + E T L+L L R + A K G + G
Sbjct: 105 NNTDLECAQKNNIKVVRVPAYSPHAVAEHTMALLLSLVRKIHKAYNRTKDGNFSLDGLLG 164
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+L K + I G G++G+ FGM I+ DP+ + + +++ ++ ++
Sbjct: 165 FDLYKKKIGIFGTGKIGQTFMGICQGFGMEILCHDPYPNEEVVKKYNARYVDQATLFKEC 224
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
D I+LH PL ST+ I+ + KKG IIN GRG L++ + + ALKSG+
Sbjct: 225 DIISLHCPLTFSTQYVIDRKTIDIMKKGAIIINTGRGKLMRTDEVIAALKSGQ 277
>UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase
C1773.17c; n=3; Schizosaccharomyces pombe|Rep: Putative
2-hydroxyacid dehydrogenase C1773.17c -
Schizosaccharomyces pombe (Fission yeast)
Length = 340
Score = 92.7 bits (220), Expect = 5e-18
Identities = 49/174 (28%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N+DVD A + GV V N P + L + R A +L+ G+W + L
Sbjct: 95 NNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLGKWRQNLSLT 154
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQCAQFHCTKMELEDIWPL 357
+ GK + I+G+G +G+ A ++ G I+ + + A++ + + + +++
Sbjct: 155 DDPYGKRVGIIGMGAIGKSFAQKILPLGCEIVYHNRNRLEAEEEKRLGASFVSFDELLSS 214
Query: 358 ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+D I+++ PL +T + I+ ++ K GV IIN RG +I E F++A+KSGK
Sbjct: 215 SDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGK 268
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 92.3 bits (219), Expect = 6e-18
Identities = 52/179 (29%), Positives = 91/179 (50%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 171
+++ + S +G+ ++N G + +L TL+L L R V +++G W L
Sbjct: 93 NHLPITSCQSRGIRIVNTQGVLTDATADLALTLLLSLTRRVREGEALVRSGHWKGWAPDL 152
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH---CTKMELE 342
G+ L GKT ILG G +GR A R++A GM +I ++ + F ++ L+
Sbjct: 153 LLGTGLTGKTCGILGSGPIGRAFARRVWAIGMKVIFWNR-EGNQKPVDFGVDIAARLPLD 211
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ +D ++LH PL ++TR +N + L G +IN RGG++ E ++ L GK
Sbjct: 212 ELLRQSDVLSLHCPLTDTTRGLLNREKLDLLPHGAFLINTARGGILDEQAVMELLHQGK 270
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 92.3 bits (219), Expect = 6e-18
Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 6/178 (3%)
Frame = +1
Query: 4 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 165
N+DV +A K+G+ V PG NA + E+ ++ RH ++ LK G WD
Sbjct: 94 NVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWLKDGEWDSDYLQAY 153
Query: 166 ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELED 345
+ G+EL GKT+ ++G G VG+ +A + AF I +DP++ D K L+
Sbjct: 154 VKFKGNELTGKTVGMIGFGAVGQRIAKLLTAFDCKIKYYDPYIQDDHPLY---EKASLKT 210
Query: 346 IWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ +D +++H P E T I+ K+ +N R ++ D L LK K
Sbjct: 211 VFSDSDIVSVHLPRTEETLGLIDRQYFDLMKESAIFVNTSRAVVVNREDLLFVLKEHK 268
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 92.3 bits (219), Expect = 6e-18
Identities = 56/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY 174
D I V +A + G+ V N P NA S E L++ LAR +V ++ W RA
Sbjct: 70 DFIPVQAASRLGIAVTNTPSVNAKSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAA 129
Query: 175 TGS-ELAGKTLAILGLGRVGREVAT-RMYAFGMNIIGFDPFVSADQCA-QFHCTKMELED 345
GS E+AGK L ++G G +G+ +A FGMN++ + D+ FH L D
Sbjct: 130 PGSCEIAGKALGLIGYGGIGQAIAQIGKLGFGMNVLAATRWPREDEDGVSFH----PLTD 185
Query: 346 IWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+ AD + + PL E TRN ++ +++ ++NV RG ++ E AL++G
Sbjct: 186 VAAKADILVVACPLSEETRNLVSEEIIAAMPPNAILVNVARGPIVDEAALSAALRAG 242
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 92.3 bits (219), Expect = 6e-18
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
DNID + A K+ + ++ APGA+ SA ELT L++ AR + + K G + + G
Sbjct: 92 DNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGIFKK--IEG 149
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM--ELEDIWP 354
ELAGKT+ I+G GR+G +VA A MN+I +D ++ + A ++ LE++
Sbjct: 150 IELAGKTIGIVGFGRIGTKVAKVCKALDMNVIAYD-VINIKEKANIVGVRVAESLEELLK 208
Query: 355 LADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQ 501
+D IT H + + + +N D K IIN R +I L+
Sbjct: 209 NSDVITFHVTVGKDAKPILNKDTFNYIKDNAIIINTSRAVVIDGKALLE 257
>UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Legionella pneumophila|Rep: D-3-phosphoglycerate
dehydrogenase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 295
Score = 91.9 bits (218), Expect = 8e-18
Identities = 57/170 (33%), Positives = 87/170 (51%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
D+ID D+ K+ + V NA G + EL LM+ LARH+ + + R TG
Sbjct: 77 DHIDRDAVSKRNIPVKNAAGYANTAVSELVFGLMISLARHIPDNNQRI---REQGITNTG 133
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
EL K L I+G G +G EVA AF M I +D +++ L+D++ +
Sbjct: 134 IELKNKVLGIVGYGAIGAEVARLAKAFQMTTIIYD-----------RKSQVTLDDLFSQS 182
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALK 510
D++TLH PL T+ +N +L Q KK +IN RG ++ +D +AL+
Sbjct: 183 DFVTLHVPLTNETKGMVNLRLLSQMKKSAYLINCARGPIVVNSDLKKALE 232
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 91.9 bits (218), Expect = 8e-18
Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 3/169 (1%)
Frame = +1
Query: 19 SAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGSELAG 195
+A +GV V NAP N+ S E+T L+L + R + A A++ G W+ R G EL
Sbjct: 81 AAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGMELHT 140
Query: 196 KTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYI 369
+TL ++G G + R VA GM ++ + P V AD + L+D+ +D +
Sbjct: 141 RTLGLVGFGAIARHVAQIAGQGLGMRVMAWSPSVPADVFEGAGVMRANSLDDLLVASDVL 200
Query: 370 TLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSG 516
+LH P S R I+A L + K+G +IN RGG + +AL++G
Sbjct: 201 SLHRPAQGSGRPTIDASALFRLKQGAILINTSRGGEVDGPALAEALEAG 249
>UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospirillum
gryphiswaldense|Rep: Glycolate reductase -
Magnetospirillum gryphiswaldense
Length = 330
Score = 91.9 bits (218), Expect = 8e-18
Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 6/179 (3%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 171
+++D+ +A + G+ + AP A + + L+L R L+ GRW +
Sbjct: 92 NHLDLQAARRHGIALAYAPEAVTEATADTAMLLLLAACRRAHEFQAQLRQGRWGAWNAWE 151
Query: 172 YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF---VSADQCAQFHCTKMELE 342
G + G+ L ++G+GR+GR VA R AFGM+I F S + A +H + L+
Sbjct: 152 NLGWDPGGQILGLVGMGRIGRAVARRARAFGMDIHYFQRNRLESSLEDGATYHSS---LD 208
Query: 343 DIWPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
++ ++ +++LHTP T+ FINA L K G IN RG + + + AL+SGK
Sbjct: 209 SLFAISRFVSLHTPTTPETKGFINAQALSWLKDGAIFINTARGDQVDDDALIAALRSGK 267
>UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter
ATP-binding subunit; n=4; Bacteria|Rep:
Spermidine/putrescine ABC transporter ATP-binding
subunit - marine gamma proteobacterium HTCC2080
Length = 395
Score = 91.9 bits (218), Expect = 8e-18
Identities = 58/185 (31%), Positives = 94/185 (50%), Gaps = 16/185 (8%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV---VPASTALKAGRWDRAL 171
+NI + + G+ V N PGANA + EL +L+ +R + + +L ++A+
Sbjct: 62 NNIPLSHCTELGIPVFNTPGANANAVKELVAAGLLLASRDILGGIDFVNSLSEDLDEQAM 121
Query: 172 ----------YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 321
+ G+EL GKTL +LGLG +G VA GM+++GFDP +S + Q
Sbjct: 122 GPLLEAEKKRFAGAELKGKTLGVLGLGAIGSLVAQLGLELGMDVVGFDPAISIEAAWQLP 181
Query: 322 CTKMELEDIWPL---ADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETD 492
+ +E++ L ADYI++H P IEST + IN + LK + ++N R ++
Sbjct: 182 SSVKRMENMQALFSRADYISIHVPAIESTHHLINQETLKYFRSDACLLNFAREQIVDTEA 241
Query: 493 FLQAL 507
AL
Sbjct: 242 VAAAL 246
>UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=7; cellular organisms|Rep: 2-hydroxyacid
dehydrogenase, D-isomer specific - Methanococcus
maripaludis
Length = 318
Score = 91.9 bits (218), Expect = 8e-18
Identities = 58/177 (32%), Positives = 89/177 (50%), Gaps = 6/177 (3%)
Frame = +1
Query: 7 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL----- 171
+D A GV V N P + S +L + +L ++V + ++K+G W +
Sbjct: 79 VDTTLAKDHGVIVTNVPAYSTDSVAQLVFSFILEHCQNVSKYTESVKSGDWVNSKDFSYQ 138
Query: 172 -YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 348
+ ELAGK+L I+G G +G++VA AFGMN++ VS + + + E+I
Sbjct: 139 KFPIIELAGKSLGIIGFGAIGKKVAEIGNAFGMNVLVNTRTVSKTD--EINVNFVSKEEI 196
Query: 349 WPLADYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
+ +D++TLH PL T +N L KK +IN GRGGL+ E D AL K
Sbjct: 197 FKNSDFLTLHCPLNNETDKIVNEKTLNLMKKSAILINTGRGGLVNEKDLANALNLEK 253
>UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=51;
Bacteria|Rep: 2-hydroxyacid dehydrogenase homolog -
Haemophilus influenzae
Length = 331
Score = 91.9 bits (218), Expect = 8e-18
Identities = 49/173 (28%), Positives = 86/173 (49%)
Frame = +1
Query: 1 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 180
+N+D+ +A + G+ V+ P + + E T LM+ L R + A + + G
Sbjct: 80 NNVDLKAAQELGIQVVRVPAYSPEAVAEHTIGLMMTLNRRIHRAYQRTREANFSLEGLIG 139
Query: 181 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLA 360
+ G+T+ ++G G++G V + FGMNI+ +DPF + + +EL++++ +
Sbjct: 140 FNMYGRTVGVIGTGKIGIAVMRILKGFGMNILAYDPFKN-PVVEELGGQYVELDELYAKS 198
Query: 361 DYITLHTPLIESTRNFINADVLKQCKKGVKIINVGRGGLIQETDFLQALKSGK 519
ITLH P + +N + + K GV I+N RG LI + ALK K
Sbjct: 199 HVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRK 251
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 555,519,554
Number of Sequences: 1657284
Number of extensions: 12484440
Number of successful extensions: 58504
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 51943
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 57590
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 32619212418
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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