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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ovS307F10f
         (489 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A1ZBT5 Cluster: Mediator of RNA polymerase II transcrip...   162   3e-39
UniRef50_Q96G25 Cluster: Mediator of RNA polymerase II transcrip...   133   2e-30
UniRef50_UPI0000E47D25 Cluster: PREDICTED: similar to MGC80409 p...   126   3e-28
UniRef50_Q4SRU6 Cluster: Chromosome undetermined SCAF14488, whol...   121   1e-26
UniRef50_Q86E25 Cluster: Clone ZZZ31 mRNA sequence; n=1; Schisto...    81   1e-14
UniRef50_Q9U1W2 Cluster: Mediator of RNA polymerase II transcrip...    74   2e-12
UniRef50_A7T1N3 Cluster: Predicted protein; n=2; Nematostella ve...    58   1e-07
UniRef50_A3LN10 Cluster: Predicted protein; n=7; Saccharomycetal...    35   0.84 
UniRef50_A2FUV0 Cluster: Putative uncharacterized protein; n=1; ...    34   1.5  
UniRef50_Q6C314 Cluster: Yarrowia lipolytica chromosome F of str...    34   2.0  
UniRef50_Q2G6P6 Cluster: Putative uncharacterized protein; n=1; ...    33   3.4  
UniRef50_Q22258 Cluster: Serine/threonine-protein kinase ATR; n=...    33   3.4  
UniRef50_Q01UW3 Cluster: Asparagine synthase; n=1; Solibacter us...    33   4.5  
UniRef50_UPI00006CD156 Cluster: Eukaryotic aspartyl protease fam...    32   6.0  
UniRef50_Q7VPA3 Cluster: Protease III; n=3; Pasteurellaceae|Rep:...    32   6.0  
UniRef50_A2DPM5 Cluster: PIKK family atypical protein kinase; n=...    32   6.0  
UniRef50_Q5UP02 Cluster: Uncharacterized protein L750; n=1; Acan...    32   6.0  
UniRef50_A7RWZ6 Cluster: Predicted protein; n=1; Nematostella ve...    32   7.9  
UniRef50_A6RAF4 Cluster: Putative uncharacterized protein; n=1; ...    32   7.9  

>UniRef50_A1ZBT5 Cluster: Mediator of RNA polymerase II
           transcription subunit 8; n=8; Endopterygota|Rep:
           Mediator of RNA polymerase II transcription subunit 8 -
           Drosophila melanogaster (Fruit fly)
          Length = 252

 Score =  162 bits (394), Expect = 3e-39
 Identities = 73/120 (60%), Positives = 95/120 (79%)
 Frame = +2

Query: 125 QREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLSK 304
           QR+EK  E T+  +L R+NDLK A+ ++I KLE EYETINWPTFLDN+AI+S HLTGL+K
Sbjct: 2   QRDEKLFELTLDTVLQRLNDLKLAVLSMIQKLELEYETINWPTFLDNFAIISSHLTGLTK 61

Query: 305 ILQAEQAASLRSRIVLPLQLSCERDETLAHLTEGRVPACTHDLVPDLLRTKPEPQAEQRL 484
           IL  EQ   LR+R VLPL +S +RD+TL ++TEGRVP  +HD+VPD LRT+P+P  EQ++
Sbjct: 62  ILAKEQCPPLRNRTVLPLLVSMDRDDTLINITEGRVPVFSHDIVPDYLRTRPDPITEQKM 121


>UniRef50_Q96G25 Cluster: Mediator of RNA polymerase II
           transcription subunit 8; n=45; Euteleostomi|Rep:
           Mediator of RNA polymerase II transcription subunit 8 -
           Homo sapiens (Human)
          Length = 268

 Score =  133 bits (321), Expect = 2e-30
 Identities = 60/119 (50%), Positives = 90/119 (75%)
 Frame = +2

Query: 125 QREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLSK 304
           QREEKQLEA++ A+L++V DLK ++ + I KLE EY  + WP+ LD++A+LSG L  L+K
Sbjct: 2   QREEKQLEASLDALLSQVADLKNSLGSFICKLENEYGRLTWPSVLDSFALLSGQLNTLNK 61

Query: 305 ILQAEQAASLRSRIVLPLQLSCERDETLAHLTEGRVPACTHDLVPDLLRTKPEPQAEQR 481
           +L+ E+    R+++++PL LS +RDE L   TEGRVP  +H++VPD LRTKP+P+ E++
Sbjct: 62  VLKHEKTPLFRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQ 120


>UniRef50_UPI0000E47D25 Cluster: PREDICTED: similar to MGC80409
           protein; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80409 protein -
           Strongylocentrotus purpuratus
          Length = 150

 Score =  126 bits (303), Expect = 3e-28
 Identities = 57/119 (47%), Positives = 91/119 (76%)
 Frame = +2

Query: 125 QREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLSK 304
           Q ++K L+ ++  IL+RVNDLK A+  L+ KLE  +ET+NWP+ L+++A+LSG +  L++
Sbjct: 2   QNQDKVLDNSLDYILSRVNDLKKALTDLLMKLEHHHETLNWPSVLNSFALLSGQINTLNR 61

Query: 305 ILQAEQAASLRSRIVLPLQLSCERDETLAHLTEGRVPACTHDLVPDLLRTKPEPQAEQR 481
            L++++   L++ I+LPL+LS +RDE L  +TEGRV +  HD+VP+ LRTKPEP++E+R
Sbjct: 62  HLKSDKTPVLKNLIILPLKLSQDRDEELEKVTEGRVASFNHDVVPNYLRTKPEPESEER 120


>UniRef50_Q4SRU6 Cluster: Chromosome undetermined SCAF14488, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14488, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 324

 Score =  121 bits (291), Expect = 1e-26
 Identities = 58/130 (44%), Positives = 90/130 (69%), Gaps = 12/130 (9%)
 Frame = +2

Query: 128 REEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLSKI 307
           REEKQLE ++ ++++RV  +K A+ + I KLE EYE + WP+ LDN+A+LSG L  ++K+
Sbjct: 1   REEKQLETSVESLISRVAHVKAALHSFIYKLENEYERLMWPSVLDNFALLSGQLNTINKL 60

Query: 308 LQAEQAASLRSRIVLPLQLSCERDETLA------------HLTEGRVPACTHDLVPDLLR 451
           L+ E+  S R+++++PL LS +RDE LA             LTE R+P  +H++VPD LR
Sbjct: 61  LRNEKTPSFRNQVIIPLLLSPDRDEDLAVKVFTILVTLPQKLTEQRLPVFSHEIVPDYLR 120

Query: 452 TKPEPQAEQR 481
           TKP+P+ E++
Sbjct: 121 TKPDPEVEEQ 130


>UniRef50_Q86E25 Cluster: Clone ZZZ31 mRNA sequence; n=1;
           Schistosoma japonicum|Rep: Clone ZZZ31 mRNA sequence -
           Schistosoma japonicum (Blood fluke)
          Length = 197

 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 43/119 (36%), Positives = 69/119 (57%)
 Frame = +2

Query: 119 MQQREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGL 298
           MQ  E++QLE  I  +   V  LK  IQ L+ K ET+ +  +WP +L   A+ +  L  +
Sbjct: 1   MQIAEKRQLE-NINILYTAVYKLKQKIQDLVIKFETQGDQCDWPRYLSTLALCASELGEI 59

Query: 299 SKILQAEQAASLRSRIVLPLQLSCERDETLAHLTEGRVPACTHDLVPDLLRTKPEPQAE 475
            KIL++++ ++  + ++ P+ L+ E D  LA +TE R+    HD VP  LRTK +P+ E
Sbjct: 60  RKILESDRFSNEHTLVLTPIVLNPEHDANLAKITEERLSLFNHDTVPQYLRTKLDPKVE 118


>UniRef50_Q9U1W2 Cluster: Mediator of RNA polymerase II
           transcription subunit 8; n=3; Caenorhabditis|Rep:
           Mediator of RNA polymerase II transcription subunit 8 -
           Caenorhabditis elegans
          Length = 297

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 8/133 (6%)
 Frame = +2

Query: 101 PFTTMNMQQREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILS 280
           P  T N Q   EK  +AT + I  RV D K  I+ L+  L+ + E   WP  L+ ++ L+
Sbjct: 8   PPVTSNYQGEPEKIAQATDMMI-KRVTDAKKIIEELLQMLDLQ-EKCPWPLMLEKFSTLA 65

Query: 281 GHLTGLSKILQA--------EQAASLRSRIVLPLQLSCERDETLAHLTEGRVPACTHDLV 436
             ++ L   ++         +    LRS +++  +L  E DETL   T+GRV +  H LV
Sbjct: 66  SFMSSLQSSVRKSGMPHGHEDYGQFLRSHVLVTQRLQYEPDETLQRATQGRVMSWNHALV 125

Query: 437 PDLLRTKPEPQAE 475
           P+ LRTKP P+ E
Sbjct: 126 PEYLRTKPNPEME 138


>UniRef50_A7T1N3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 264

 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 46/134 (34%), Positives = 72/134 (53%), Gaps = 12/134 (8%)
 Frame = +2

Query: 113 MNMQQREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILS--GH 286
           M MQQ EEK +E ++ AI +RV +++ ++   + KLE   E +NWP+ LDN+A+LS   H
Sbjct: 1   MRMQQ-EEKLIETSLEAITSRVQEVRDSVHTFLAKLER--EPLNWPSVLDNFALLSVPDH 57

Query: 287 LTGL--SKILQAEQAASLRSRIVLPLQLSCE---RDETLAHLTEGRVPA-----CTHDLV 436
           L      ++ +AEQ+  + S  +       +    +E L  LT+    A        + V
Sbjct: 58  LRTKYEPEVEEAEQSLVVASASITQENAQKQINHLNELLTTLTDMITSAKEDWEGEQNSV 117

Query: 437 PDLLRTKPEPQAEQ 478
           PD LRTK EP+ E+
Sbjct: 118 PDHLRTKYEPEVEE 131


>UniRef50_A3LN10 Cluster: Predicted protein; n=7;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 355

 Score = 35.1 bits (77), Expect = 0.84
 Identities = 24/88 (27%), Positives = 42/88 (47%)
 Frame = +2

Query: 74  N*KVTIVYLPFTTMNMQQREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPT 253
           N K T+V LP  +    + +     A I+   N +N+    +Q LIN ++TE  T  +  
Sbjct: 97  NVKCTVV-LPVISKVAVREKLISYGADIILFGNNINEADQHLQNLINSIDTEKTTAIYCH 155

Query: 254 FLDNYAILSGHLTGLSKILQAEQAASLR 337
             +N  I  GH T + +++Q    A ++
Sbjct: 156 PFNNPLIWQGHATLVDEVVQEVSKAEVK 183


>UniRef50_A2FUV0 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 358

 Score = 34.3 bits (75), Expect = 1.5
 Identities = 26/96 (27%), Positives = 43/96 (44%)
 Frame = +2

Query: 122 QQREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLS 301
           Q+RE  Q+   +   L R  D+K A  A  N ++T+   I     +DN ++LS     ++
Sbjct: 240 QERELTQMRQKLQETLKRAADVKKASDASSNNMKTQLNAI----LIDNQSLLSSVPKSIA 295

Query: 302 KILQAEQAASLRSRIVLPLQLSCERDETLAHLTEGR 409
              QA+    L+       QL  +R++    L E R
Sbjct: 296 VETQAQTNTELQDETRKLEQLFQKREQDENRLAEAR 331


>UniRef50_Q6C314 Cluster: Yarrowia lipolytica chromosome F of strain
            CLIB122 of Yarrowia lipolytica; n=5; Ascomycota|Rep:
            Yarrowia lipolytica chromosome F of strain CLIB122 of
            Yarrowia lipolytica - Yarrowia lipolytica (Candida
            lipolytica)
          Length = 923

 Score = 33.9 bits (74), Expect = 2.0
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
 Frame = +2

Query: 146  EATIVAILNRVNDLKTAIQALINKLE-TEYETINWPTFLDNYAI-LSGH-LTGLSKILQA 316
            EA   A L+    L+ A+Q LI++L  T  E+ +  T    + + L G  LTG   I+Q 
Sbjct: 830  EAVDTATLSEYKGLEEAVQFLISQLSLTPLESSDEVTSASTHTLKLFGKTLTGEKVIVQI 889

Query: 317  EQAASLRSRIVLPLQLSCERDETLAHLTEGRV 412
            + AAS R+ +V+  + +   DE +A L  G V
Sbjct: 890  KMAASQRTGVVVQCK-ARSGDEEVAELVAGFV 920


>UniRef50_Q2G6P6 Cluster: Putative uncharacterized protein; n=1;
           Novosphingobium aromaticivorans DSM 12444|Rep: Putative
           uncharacterized protein - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 864

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 17/36 (47%), Positives = 18/36 (50%)
 Frame = +2

Query: 320 QAASLRSRIVLPLQLSCERDETLAHLTEGRVPACTH 427
           QAAS R R+   LQ      E LAHL EGR     H
Sbjct: 274 QAASFRERVEASLQAFTASAEDLAHLAEGRFETLAH 309


>UniRef50_Q22258 Cluster: Serine/threonine-protein kinase ATR; n=3;
            Caenorhabditis|Rep: Serine/threonine-protein kinase ATR -
            Caenorhabditis elegans
          Length = 2531

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 12/39 (30%), Positives = 25/39 (64%)
 Frame = +2

Query: 173  RVNDLKTAIQALINKLETEYETINWPTFLDNYAILSGHL 289
            +++DL+  I+++  +++T  E I W  F   YA+L+ H+
Sbjct: 1993 QISDLRQNIKSMNREIQTALEHIGWRAFYPAYAVLARHI 2031


>UniRef50_Q01UW3 Cluster: Asparagine synthase; n=1; Solibacter
           usitatus Ellin6076|Rep: Asparagine synthase - Solibacter
           usitatus (strain Ellin6076)
          Length = 632

 Score = 32.7 bits (71), Expect = 4.5
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
 Frame = +2

Query: 188 KTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLSKILQAEQAASLRSRIVLP-LQL 364
           K  ++AL   L   YET    T L N   ++G LTG   +    Q+  L ++ +LP   L
Sbjct: 436 KAGLEALRALLTIAYETDEVLTRLLNRVDIAGQLTGRHVL---NQSLYLNNKTILPGYIL 492

Query: 365 SCERDET-LAHLTEGRVPACTHDLV 436
           S   D   +AH  E R+P   H +V
Sbjct: 493 SALGDRVEMAHSIEARLPFLDHHVV 517


>UniRef50_UPI00006CD156 Cluster: Eukaryotic aspartyl protease family
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Eukaryotic aspartyl protease family protein -
           Tetrahymena thermophila SB210
          Length = 386

 Score = 32.3 bits (70), Expect = 6.0
 Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +2

Query: 137 KQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTF-LDNY 268
           K  E T+  +L RVN LK  IQAL+NKL       +WP   ++NY
Sbjct: 24  KPQENTLQKLL-RVNSLKGNIQALLNKLFPSNMVSSWPEVKINNY 67


>UniRef50_Q7VPA3 Cluster: Protease III; n=3; Pasteurellaceae|Rep:
           Protease III - Haemophilus ducreyi
          Length = 984

 Score = 32.3 bits (70), Expect = 6.0
 Identities = 17/39 (43%), Positives = 24/39 (61%)
 Frame = +3

Query: 312 KPNKQLHCGLELFYHFN*VANVMKHWLI*QKAEFQLALM 428
           KPN +LH  LE FYH +  AN++K  L   ++  QLA +
Sbjct: 230 KPNSKLHTELEKFYHTHYSANLVKAVLYSNQSIEQLATL 268


>UniRef50_A2DPM5 Cluster: PIKK family atypical protein kinase; n=1;
           Trichomonas vaginalis G3|Rep: PIKK family atypical
           protein kinase - Trichomonas vaginalis G3
          Length = 2171

 Score = 32.3 bits (70), Expect = 6.0
 Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
 Frame = +2

Query: 53  LLKSNKEN*KVTIVYLPFTTMNMQQREEKQLE-ATIVAILNRVNDLKTAIQALINKLETE 229
           LLK N +N    +++  FT+++ +Q +E +LE  + V +    N +  AIQ L++ L++ 
Sbjct: 454 LLKYNNDNPSTEVMHRIFTSISTEQDKETRLEILSNVNVKVADNAIILAIQQLLHDLDSS 513

Query: 230 YETINWPTF--LDNY----AILSGHLTGLSKILQAEQAASLRSRIVLPLQL 364
              +++     L NY     ILS  L+   K LQ   A  +    +LP  +
Sbjct: 514 VRRLSFEIMVKLANYEAVPPILSSILSERLKYLQ--NAPEILKENILPFSV 562


>UniRef50_Q5UP02 Cluster: Uncharacterized protein L750; n=1;
           Acanthamoeba polyphaga mimivirus|Rep: Uncharacterized
           protein L750 - Mimivirus
          Length = 338

 Score = 32.3 bits (70), Expect = 6.0
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = +2

Query: 185 LKTAIQALINKLETEYETINWPTFLDNYAILSGHLTGLSKILQAEQ 322
           +   I+  IN L ++ + IN PTFLDNY+     +T L KI+   Q
Sbjct: 5   INNKIKITIN-LPSKIDWINIPTFLDNYSDDESKITVLKKIVSKNQ 49


>UniRef50_A7RWZ6 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 4477

 Score = 31.9 bits (69), Expect = 7.9
 Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
 Frame = +2

Query: 104  FTTMNMQQREEKQLEATIVAILNRVNDLKTAIQALINKLETEYETINWPTFLDNYAILSG 283
            FTT+++  +E++  E+T+ A+L+++NDL    +    KL  E    + P+F       SG
Sbjct: 3804 FTTVSLLVKEQR--ESTVTALLSKINDLYLPTKEGYLKLSNELIFYDCPSFERRARDFSG 3861

Query: 284  HLTGLSK--ILQAEQAASLRSRIVLPLQL 364
                +++   L A++ A L +  +LP +L
Sbjct: 3862 DFMDIAREGELTADRLAYLLN--LLPTRL 3888


>UniRef50_A6RAF4 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 760

 Score = 31.9 bits (69), Expect = 7.9
 Identities = 13/25 (52%), Positives = 18/25 (72%)
 Frame = +2

Query: 407 RVPACTHDLVPDLLRTKPEPQAEQR 481
           R+PA +H+  PDL  TKP+P A +R
Sbjct: 368 RLPAVSHNASPDLQTTKPKPVATKR 392


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 411,289,308
Number of Sequences: 1657284
Number of extensions: 6807414
Number of successful extensions: 17812
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 17468
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17806
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 28019067077
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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