Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS307C04f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BX538023-1|CAD97969.1| 525|Homo sapiens hypothetical protein pr... 140 2e-33
BC126160-1|AAI26161.1| 714|Homo sapiens solute carrier family 1... 140 2e-33
BC126158-1|AAI26159.1| 714|Homo sapiens solute carrier family 1... 140 2e-33
BC063528-1|AAH63528.1| 338|Homo sapiens SLC12A8 protein protein. 140 2e-33
AF389851-1|AAK94307.1| 584|Homo sapiens solute carrier family 1... 140 2e-33
AF345197-1|AAO49174.1| 714|Homo sapiens cation-chloride cotrans... 140 2e-33
AF390442-1|AAM73657.1| 731|Homo sapiens solute carrier family 1... 138 8e-33
U30246-1|AAC50561.1| 1212|Homo sapiens bumetanide-sensitive Na-K... 65 1e-10
BC033003-1|AAH33003.1| 1150|Homo sapiens SLC12A2 protein protein. 65 1e-10
AY280459-1|AAP33906.1| 1212|Homo sapiens bumetanide-sensitive Na... 65 1e-10
U58130-1|AAB07364.1| 1099|Homo sapiens bumetanide-sensitive Na-K... 63 7e-10
BC098390-1|AAH98390.1| 1083|Homo sapiens solute carrier family 1... 59 1e-08
AK024497-1|BAB15787.1| 721|Homo sapiens FLJ00105 protein protein. 59 1e-08
AK024493-1|BAB15783.1| 780|Homo sapiens FLJ00098 protein protein. 59 1e-08
AF105365-1|AAD39741.1| 1083|Homo sapiens K-Cl cotransporter KCC4... 58 1e-08
U44128-1|AAC50355.1| 1030|Homo sapiens thiazide-sensitive Na-Cl ... 58 2e-08
AK129998-1|BAC85271.1| 342|Homo sapiens protein ( Homo sapiens ... 55 2e-07
BC000154-1|AAH00154.1| 538|Homo sapiens SLC12A9 protein protein. 54 4e-07
AK024494-1|BAB15784.1| 672|Homo sapiens FLJ00100 protein protein. 54 4e-07
AK024421-1|BAB15711.1| 772|Homo sapiens FLJ00010 protein protein. 54 4e-07
AF312032-7|AAK21009.1| 627|Homo sapiens cation-chloride cotrans... 54 4e-07
AF312032-6|AAK21008.1| 914|Homo sapiens cation-chloride cotrans... 54 4e-07
AF284422-1|AAF88060.1| 914|Homo sapiens cation-chloride cotrans... 54 4e-07
AB033284-1|BAB40456.1| 914|Homo sapiens cation chloride cotrans... 54 4e-07
X91220-1|CAA62613.1| 1021|Homo sapiens NaCl electroneutral Thiaz... 53 7e-07
DQ138323-1|ABA02873.1| 1141|Homo sapiens potassium chloride cotr... 53 7e-07
BC126243-1|AAI26244.1| 1099|Homo sapiens solute carrier family 1... 53 7e-07
BC126241-1|AAI26242.1| 1099|Homo sapiens solute carrier family 1... 53 7e-07
BC070107-1|AAH70107.2| 1091|Homo sapiens solute carrier family 1... 53 7e-07
AL117500-1|CAB55965.1| 1014|Homo sapiens hypothetical protein pr... 53 7e-07
AF531260-1|AAQ10028.1| 1091|Homo sapiens K-Cl cotransporter KCC3... 53 7e-07
AF531259-1|AAQ10027.1| 1091|Homo sapiens K-Cl cotransporter KCC3... 53 7e-07
AF531258-1|AAQ10026.1| 1135|Homo sapiens K-Cl cotransporter KCC3... 53 7e-07
AF477977-1|AAL85335.1| 1011|Homo sapiens K-Cl cotransporter KCC3... 53 7e-07
AF314956-2|AAM96216.1| 1099|Homo sapiens potassium-chloride tran... 53 7e-07
AF314956-1|AAM96215.1| 1150|Homo sapiens potassium-chloride tran... 53 7e-07
AF116242-1|AAF24986.1| 1150|Homo sapiens K-Cl cotransporter KCC3... 53 7e-07
AF108831-1|AAD25337.1| 1099|Homo sapiens K:Cl cotransporter 3 pr... 53 7e-07
AF105366-1|AAD39742.1| 1150|Homo sapiens K-Cl cotransporter KCC3... 53 7e-07
BC132670-1|AAI32671.1| 1116|Homo sapiens solute carrier family 1... 52 9e-07
BC132668-1|AAI32669.1| 1116|Homo sapiens solute carrier family 1... 52 9e-07
AL162458-7|CAH74054.2| 1116|Homo sapiens solute carrier family 1... 52 9e-07
AF208159-1|AAG43493.1| 1116|Homo sapiens electroneutral potassiu... 52 9e-07
AB033002-1|BAA86490.1| 1101|Homo sapiens KIAA1176 protein protein. 52 9e-07
U55054-1|AAC50563.1| 1085|Homo sapiens K-Cl cotransporter protein. 51 2e-06
BC021193-1|AAH21193.1| 1085|Homo sapiens solute carrier family 1... 51 2e-06
AF054506-1|AAC39685.1| 1068|Homo sapiens erythroid K:Cl cotransp... 51 2e-06
AF054505-1|AAC39684.1| 1011|Homo sapiens erythroid K:Cl cotransp... 51 2e-06
AF047338-1|AAC32815.1| 1085|Homo sapiens erythroid K:Cl cotransp... 51 2e-06
BC051744-1|AAH51744.1| 943|Homo sapiens SLC12A6 protein protein. 49 9e-06
U47742-1|AAC50662.1| 2004|Homo sapiens monocytic leukaemia zinc ... 31 1.9
AK090458-1|BAC03439.1| 487|Homo sapiens FLJ00379 protein protein. 30 4.3
AK024420-1|BAB15710.1| 540|Homo sapiens FLJ00009 protein protein. 30 4.3
>BX538023-1|CAD97969.1| 525|Homo sapiens hypothetical protein
protein.
Length = 525
Score = 140 bits (340), Expect = 2e-33
Identities = 65/137 (47%), Positives = 90/137 (65%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+SS++SC+G +Y
Sbjct: 81 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLY 140
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 141 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 200
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 201 NFMLTYVAVDYSYFSLS 217
>BC126160-1|AAI26161.1| 714|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 8 protein.
Length = 714
Score = 140 bits (340), Expect = 2e-33
Identities = 65/137 (47%), Positives = 90/137 (65%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+SS++SC+G +Y
Sbjct: 270 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLY 329
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 330 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 389
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 390 NFMLTYVAVDYSYFSLS 406
>BC126158-1|AAI26159.1| 714|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 8 protein.
Length = 714
Score = 140 bits (340), Expect = 2e-33
Identities = 65/137 (47%), Positives = 90/137 (65%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+SS++SC+G +Y
Sbjct: 270 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLY 329
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 330 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 389
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 390 NFMLTYVAVDYSYFSLS 406
>BC063528-1|AAH63528.1| 338|Homo sapiens SLC12A8 protein protein.
Length = 338
Score = 140 bits (340), Expect = 2e-33
Identities = 65/137 (47%), Positives = 90/137 (65%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+SS++SC+G +Y
Sbjct: 18 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLY 77
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 78 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 137
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 138 NFMLTYVAVDYSYFSLS 154
>AF389851-1|AAK94307.1| 584|Homo sapiens solute carrier family 12
member 8 protein.
Length = 584
Score = 140 bits (340), Expect = 2e-33
Identities = 65/137 (47%), Positives = 90/137 (65%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+SS++SC+G +Y
Sbjct: 140 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLY 199
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 200 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 259
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 260 NFMLTYVAVDYSYFSLS 276
>AF345197-1|AAO49174.1| 714|Homo sapiens cation-chloride
cotransporter 9 protein.
Length = 714
Score = 140 bits (340), Expect = 2e-33
Identities = 65/137 (47%), Positives = 90/137 (65%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+SS++SC+G +Y
Sbjct: 270 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLY 329
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 330 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 389
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 390 NFMLTYVAVDYSYFSLS 406
>AF390442-1|AAM73657.1| 731|Homo sapiens solute carrier family 12
member 8 protein.
Length = 731
Score = 138 bits (335), Expect = 8e-33
Identities = 64/137 (46%), Positives = 89/137 (64%)
Frame = +2
Query: 2 AAITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMY 181
AA+ FLY++F+ L A TREAL +F I +S + L L GLY+ S++SC+G +Y
Sbjct: 287 AAVGISWFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYIPSLASCMGGLY 346
Query: 182 GTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTM 361
G PR+LQ IA EKVIP L LG G+GPNK P+ ++ G +N LAPIVT+
Sbjct: 347 GAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTI 406
Query: 362 PFLITYASIDYSYFALA 412
F++TY ++DYSYF+L+
Sbjct: 407 NFMLTYVAVDYSYFSLS 423
>U30246-1|AAC50561.1| 1212|Homo sapiens bumetanide-sensitive Na-K-Cl
cotransporter protein.
Length = 1212
Score = 65.3 bits (152), Expect = 1e-10
Identities = 28/109 (25%), Positives = 56/109 (51%)
Frame = +2
Query: 77 LLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGR 256
L+ NF + + +S L+ AG++ +++SS L ++ P++ Q++ + + P + G
Sbjct: 586 LMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGY 645
Query: 257 GPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
G N P+ ++N +API++ FL +YA I++S F
Sbjct: 646 GKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVF 694
>BC033003-1|AAH33003.1| 1150|Homo sapiens SLC12A2 protein protein.
Length = 1150
Score = 65.3 bits (152), Expect = 1e-10
Identities = 28/109 (25%), Positives = 56/109 (51%)
Frame = +2
Query: 77 LLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGR 256
L+ NF + + +S L+ AG++ +++SS L ++ P++ Q++ + + P + G
Sbjct: 586 LMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGY 645
Query: 257 GPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
G N P+ ++N +API++ FL +YA I++S F
Sbjct: 646 GKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVF 694
>AY280459-1|AAP33906.1| 1212|Homo sapiens bumetanide-sensitive
Na-K-Cl cotransporter protein.
Length = 1212
Score = 65.3 bits (152), Expect = 1e-10
Identities = 28/109 (25%), Positives = 56/109 (51%)
Frame = +2
Query: 77 LLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGR 256
L+ NF + + +S L+ AG++ +++SS L ++ P++ Q++ + + P + G
Sbjct: 586 LMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGY 645
Query: 257 GPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
G N P+ ++N +API++ FL +YA I++S F
Sbjct: 646 GKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVF 694
>U58130-1|AAB07364.1| 1099|Homo sapiens bumetanide-sensitive
Na-K-2Cl cotransporter protein.
Length = 1099
Score = 62.9 bits (146), Expect = 7e-10
Identities = 29/109 (26%), Positives = 55/109 (50%)
Frame = +2
Query: 77 LLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGR 256
L+ NF + + +S L+ AG++ +++SS L ++ P+V Q++ + + L G
Sbjct: 479 LMNNFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYKALQFFAKGY 538
Query: 257 GPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
G N P+ ++N +API++ FL +YA I++S F
Sbjct: 539 GKNNEPLRGYILTFLIAMAFILIAELNTIAPIISNFFLASYALINFSCF 587
>BC098390-1|AAH98390.1| 1083|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 7 protein.
Length = 1083
Score = 58.8 bits (136), Expect = 1e-08
Identities = 37/137 (27%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL I+ A + L F + VI +L + G + S+
Sbjct: 458 AIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCG 517
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + ++P L + GHG+ N P +++ ++
Sbjct: 518 AGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKA-NGEPTWALLLTVLICETGILIASLDS 576
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 577 VAPILSMFFLMCYLFVN 593
>AK024497-1|BAB15787.1| 721|Homo sapiens FLJ00105 protein protein.
Length = 721
Score = 58.8 bits (136), Expect = 1e-08
Identities = 37/137 (27%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL I+ A + L F + VI +L + G + S+
Sbjct: 96 AIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCG 155
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + ++P L + GHG+ N P +++ ++
Sbjct: 156 AGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKA-NGEPTWALLLTVLICETGILIASLDS 214
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 215 VAPILSMFFLMCYLFVN 231
>AK024493-1|BAB15783.1| 780|Homo sapiens FLJ00098 protein protein.
Length = 780
Score = 58.8 bits (136), Expect = 1e-08
Identities = 37/137 (27%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL I+ A + L F + VI +L + G + S+
Sbjct: 155 AIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCG 214
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + ++P L + GHG+ N P +++ ++
Sbjct: 215 AGLQSLTGAPRLLQAIARDGIVPFLQVFGHGKA-NGEPTWALLLTVLICETGILIASLDS 273
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 274 VAPILSMFFLMCYLFVN 290
>AF105365-1|AAD39741.1| 1083|Homo sapiens K-Cl cotransporter KCC4
protein.
Length = 1083
Score = 58.4 bits (135), Expect = 1e-08
Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL I+ A + L F + VI +L + G + S+
Sbjct: 458 AIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCG 517
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L + G PR+LQ+IA + ++P L + GHG+ N P +++ ++
Sbjct: 518 AGLQTLTGAPRLLQAIARDGIVPFLQVFGHGKA-NGEPTWALLLTVLICETGILIASLDS 576
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 577 VAPILSMFFLMCYLFVN 593
>U44128-1|AAC50355.1| 1030|Homo sapiens thiazide-sensitive Na-Cl
protein.
Length = 1030
Score = 58.0 bits (134), Expect = 2e-08
Identities = 28/109 (25%), Positives = 54/109 (49%)
Frame = +2
Query: 77 LLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGR 256
L+ + + +S L+ AG++ +++SS L + +V Q + +++ P + G G
Sbjct: 440 LINYYQTMSMVSGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGY 499
Query: 257 GPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
G NK P+ ++N +API++ FL +YA I++S F
Sbjct: 500 GKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCF 548
>AK129998-1|BAC85271.1| 342|Homo sapiens protein ( Homo sapiens
cDNA FLJ26488 fis, clone KDN05770, highly similar to
Bumetanide-sensitive sodium-(potassium)-chloride
cotransporter 2. ).
Length = 342
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/107 (27%), Positives = 53/107 (49%)
Frame = +2
Query: 83 KNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGP 262
KN+S+ +S L+ AG++ +++SS L ++ P+V Q++ + L G G
Sbjct: 177 KNWSM---VSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNFYKALQFFAKGYGK 233
Query: 263 NKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
N P+ ++N +API++ FL +YA I++S F
Sbjct: 234 NNEPLRGYILTFLIAMAFILIAELNTIAPIISNFFLASYALINFSCF 280
>BC000154-1|AAH00154.1| 538|Homo sapiens SLC12A9 protein protein.
Length = 538
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 216 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 275
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 276 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 331
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 332 VTVFYLVAYAAVDLSCLSL 350
>AK024494-1|BAB15784.1| 672|Homo sapiens FLJ00100 protein protein.
Length = 672
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 63 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 122
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 123 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 178
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 179 VTVFYLVAYAAVDLSCLSL 197
>AK024421-1|BAB15711.1| 772|Homo sapiens FLJ00010 protein protein.
Length = 772
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 163 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 222
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 223 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 278
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 279 VTVFYLVAYAAVDLSCLSL 297
>AF312032-7|AAK21009.1| 627|Homo sapiens cation-chloride
cotransporter-interacting protein 1 isoform b protein.
Length = 627
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 305 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 364
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 365 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 420
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 421 VTVFYLVAYAAVDLSCLSL 439
>AF312032-6|AAK21008.1| 914|Homo sapiens cation-chloride
cotransporter-interacting protein 1 protein.
Length = 914
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 305 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 364
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 365 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 420
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 421 VTVFYLVAYAAVDLSCLSL 439
>AF284422-1|AAF88060.1| 914|Homo sapiens cation-chloride
cotransporter-interacting protein protein.
Length = 914
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 305 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 364
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 365 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 420
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 421 VTVFYLVAYAAVDLSCLSL 439
>AB033284-1|BAB40456.1| 914|Homo sapiens cation chloride
cotransporter 6 protein.
Length = 914
Score = 53.6 bits (123), Expect = 4e-07
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYG 184
A+ F+Y++ + T R L +++ IS L+L G+Y +++S+ + ++ G
Sbjct: 305 AVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIG 364
Query: 185 TPRVLQSIANEK----VIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINKLAPI 352
R+L ++A + ++ ++ G P +YS G +N LA +
Sbjct: 365 ASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYS----WGLVQLVLLAGKLNTLAAV 420
Query: 353 VTMPFLITYASIDYSYFAL 409
VT+ +L+ YA++D S +L
Sbjct: 421 VTVFYLVAYAAVDLSCLSL 439
>X91220-1|CAA62613.1| 1021|Homo sapiens NaCl electroneutral
Thiazide-sensitive cotransporter protein.
Length = 1021
Score = 52.8 bits (121), Expect = 7e-07
Identities = 26/109 (23%), Positives = 52/109 (47%)
Frame = +2
Query: 77 LLKNFSITADISAVIVLLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGR 256
L+ + + +S L+ ++ +++SS L + +V Q + +++ P + G G
Sbjct: 440 LINYYQTMSMVSGFAPLITVVIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGY 499
Query: 257 GPNKVPIYSMXXXXXXXXXXXXXGDINKLAPIVTMPFLITYASIDYSYF 403
G NK P+ ++N +API++ FL +YA I++S F
Sbjct: 500 GKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCF 548
>DQ138323-1|ABA02873.1| 1141|Homo sapiens potassium chloride
cotransporter KCC3a-S3 protein.
Length = 1141
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 514 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 573
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 574 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 632
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 633 VAPILSMFFLMCYLFVN 649
>BC126243-1|AAI26244.1| 1099|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 6 protein.
Length = 1099
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 472 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 531
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 532 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 590
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 591 VAPILSMFFLMCYLFVN 607
>BC126241-1|AAI26242.1| 1099|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 6 protein.
Length = 1099
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 472 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 531
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 532 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 590
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 591 VAPILSMFFLMCYLFVN 607
>BC070107-1|AAH70107.2| 1091|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 6 protein.
Length = 1091
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 464 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 523
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 524 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 582
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 583 VAPILSMFFLMCYLFVN 599
>AL117500-1|CAB55965.1| 1014|Homo sapiens hypothetical protein
protein.
Length = 1014
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 387 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 446
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 447 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 505
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 506 VAPILSMFFLMCYLFVN 522
>AF531260-1|AAQ10028.1| 1091|Homo sapiens K-Cl cotransporter
KCC3a-S2 isoform protein.
Length = 1091
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 464 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 523
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 524 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 582
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 583 VAPILSMFFLMCYLFVN 599
>AF531259-1|AAQ10027.1| 1091|Homo sapiens K-Cl cotransporter
KCC3a-S1 isoform protein.
Length = 1091
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 464 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 523
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 524 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 582
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 583 VAPILSMFFLMCYLFVN 599
>AF531258-1|AAQ10026.1| 1135|Homo sapiens K-Cl cotransporter
KCC3a-X2M isoform protein.
Length = 1135
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 508 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 567
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 568 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 626
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 627 VAPILSMFFLMCYLFVN 643
>AF477977-1|AAL85335.1| 1011|Homo sapiens K-Cl cotransporter KCC3
variant isoform protein.
Length = 1011
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 384 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 443
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 444 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 502
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 503 VAPILSMFFLMCYLFVN 519
>AF314956-2|AAM96216.1| 1099|Homo sapiens potassium-chloride
transporter-3b protein.
Length = 1099
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 472 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 531
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 532 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 590
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 591 VAPILSMFFLMCYLFVN 607
>AF314956-1|AAM96215.1| 1150|Homo sapiens potassium-chloride
transporter-3a protein.
Length = 1150
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 523 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 582
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 583 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 641
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 642 VAPILSMFFLMCYLFVN 658
>AF116242-1|AAF24986.1| 1150|Homo sapiens K-Cl cotransporter KCC3
protein.
Length = 1150
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 523 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 582
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 583 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 641
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 642 VAPILSMFFLMCYLFVN 658
>AF108831-1|AAD25337.1| 1099|Homo sapiens K:Cl cotransporter 3
protein.
Length = 1099
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 472 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 531
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 532 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 590
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 591 VAPILSMFFLMCYLFVN 607
>AF105366-1|AAD39742.1| 1150|Homo sapiens K-Cl cotransporter KCC3a
protein.
Length = 1150
Score = 52.8 bits (121), Expect = 7e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T +F+YL ++ A + L F + V+ L + G + S+
Sbjct: 523 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 582
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+IA + +IP L + GH + N P +++ ++
Sbjct: 583 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDL 641
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 642 VAPILSMFFLMCYLFVN 658
>BC132670-1|AAI32671.1| 1116|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 1116
Score = 52.4 bits (120), Expect = 9e-07
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T + +Y+ ++ A + L F + + V+ L + G + S+
Sbjct: 438 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 497
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+I+ + ++P L + GHG+ N P +++ +++
Sbjct: 498 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDE 556
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 557 VAPILSMFFLMCYMFVN 573
>BC132668-1|AAI32669.1| 1116|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 1116
Score = 52.4 bits (120), Expect = 9e-07
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T + +Y+ ++ A + L F + + V+ L + G + S+
Sbjct: 438 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 497
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+I+ + ++P L + GHG+ N P +++ +++
Sbjct: 498 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDE 556
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 557 VAPILSMFFLMCYMFVN 573
>AL162458-7|CAH74054.2| 1116|Homo sapiens solute carrier family 12,
(potassium-chloride transporter) member 5 protein.
Length = 1116
Score = 52.4 bits (120), Expect = 9e-07
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T + +Y+ ++ A + L F + + V+ L + G + S+
Sbjct: 438 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 497
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+I+ + ++P L + GHG+ N P +++ +++
Sbjct: 498 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDE 556
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 557 VAPILSMFFLMCYMFVN 573
>AF208159-1|AAG43493.1| 1116|Homo sapiens electroneutral
potassium-chloride cotransporter KCC2 protein.
Length = 1116
Score = 52.4 bits (120), Expect = 9e-07
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T + +Y+ ++ A + L F + + V+ L + G + S+
Sbjct: 438 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 497
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+I+ + ++P L + GHG+ N P +++ +++
Sbjct: 498 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDE 556
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 557 VAPILSMFFLMCYMFVN 573
>AB033002-1|BAA86490.1| 1101|Homo sapiens KIAA1176 protein protein.
Length = 1101
Score = 52.4 bits (120), Expect = 9e-07
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Frame = +2
Query: 5 AITTGTFLYLMFIITLAATVTREALLKNFSITADISAVIVLL--------LAGLYVSSMS 160
AI T + +Y+ ++ A + L F + + V+ L + G + S+
Sbjct: 430 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 489
Query: 161 SCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXXXXXXXXXGDINK 340
+ L ++ G PR+LQ+I+ + ++P L + GHG+ N P +++ +++
Sbjct: 490 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDE 548
Query: 341 LAPIVTMPFLITYASID 391
+API++M FL+ Y ++
Sbjct: 549 VAPILSMFFLMCYMFVN 565
>U55054-1|AAC50563.1| 1085|Homo sapiens K-Cl cotransporter protein.
Length = 1085
Score = 51.2 bits (117), Expect = 2e-06
Identities = 25/89 (28%), Positives = 50/89 (56%)
Frame = +2
Query: 125 LLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXX 304
+++ G + S+ + L ++ G PR+LQ+IA + +IP L + GHG+ N P +++
Sbjct: 506 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALI 564
Query: 305 XXXXXXXGDINKLAPIVTMPFLITYASID 391
++ +API++M FL+ Y ++
Sbjct: 565 AELGILIASLDMVAPILSMFFLMCYLFVN 593
>BC021193-1|AAH21193.1| 1085|Homo sapiens solute carrier family 12
(potassium/chloride transporters), member 4 protein.
Length = 1085
Score = 51.2 bits (117), Expect = 2e-06
Identities = 25/89 (28%), Positives = 50/89 (56%)
Frame = +2
Query: 125 LLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXX 304
+++ G + S+ + L ++ G PR+LQ+IA + +IP L + GHG+ N P +++
Sbjct: 506 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALI 564
Query: 305 XXXXXXXGDINKLAPIVTMPFLITYASID 391
++ +API++M FL+ Y ++
Sbjct: 565 AELGILIASLDMVAPILSMFFLMCYLFVN 593
>AF054506-1|AAC39685.1| 1068|Homo sapiens erythroid K:Cl
cotransporter splicing isoform 2 protein.
Length = 1068
Score = 51.2 bits (117), Expect = 2e-06
Identities = 25/89 (28%), Positives = 50/89 (56%)
Frame = +2
Query: 125 LLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXX 304
+++ G + S+ + L ++ G PR+LQ+IA + +IP L + GHG+ N P +++
Sbjct: 506 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALI 564
Query: 305 XXXXXXXGDINKLAPIVTMPFLITYASID 391
++ +API++M FL+ Y ++
Sbjct: 565 AELGILIASLDMVAPILSMFFLMCYLFVN 593
>AF054505-1|AAC39684.1| 1011|Homo sapiens erythroid K:Cl
cotransporter splicing isoform 1 protein.
Length = 1011
Score = 51.2 bits (117), Expect = 2e-06
Identities = 25/89 (28%), Positives = 50/89 (56%)
Frame = +2
Query: 125 LLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXX 304
+++ G + S+ + L ++ G PR+LQ+IA + +IP L + GHG+ N P +++
Sbjct: 506 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALI 564
Query: 305 XXXXXXXGDINKLAPIVTMPFLITYASID 391
++ +API++M FL+ Y ++
Sbjct: 565 AELGILIASLDMVAPILSMFFLMCYLFVN 593
>AF047338-1|AAC32815.1| 1085|Homo sapiens erythroid K:Cl
cotransporter protein.
Length = 1085
Score = 51.2 bits (117), Expect = 2e-06
Identities = 25/89 (28%), Positives = 50/89 (56%)
Frame = +2
Query: 125 LLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXX 304
+++ G + S+ + L ++ G PR+LQ+IA + +IP L + GHG+ N P +++
Sbjct: 506 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK-VNGEPTWALLLTALI 564
Query: 305 XXXXXXXGDINKLAPIVTMPFLITYASID 391
++ +API++M FL+ Y ++
Sbjct: 565 AELGILIASLDMVAPILSMFFLMCYLFVN 593
>BC051744-1|AAH51744.1| 943|Homo sapiens SLC12A6 protein protein.
Length = 943
Score = 49.2 bits (112), Expect = 9e-06
Identities = 24/89 (26%), Positives = 49/89 (55%)
Frame = +2
Query: 125 LLLAGLYVSSMSSCLGAMYGTPRVLQSIANEKVIPGLDILGHGRGPNKVPIYSMXXXXXX 304
+++ G + S+ + L ++ G PR+LQ+IA + +IP L + GH + N P +++
Sbjct: 513 VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTAAI 571
Query: 305 XXXXXXXGDINKLAPIVTMPFLITYASID 391
++ +API++M FL+ Y ++
Sbjct: 572 AELGILIASLDLVAPILSMFFLMCYLFVN 600
>U47742-1|AAC50662.1| 2004|Homo sapiens monocytic leukaemia zinc
finger protein protein.
Length = 2004
Score = 31.5 bits (68), Expect = 1.9
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Frame = -3
Query: 354 TMGASLFMSPIIMNVTVTMATTTIEYIGTLFGPLPCPSISKPGITFSLA---MLCNTLGV 184
+M S +P+IM + + +T I + G S S+P TFSLA L NT+
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765
Query: 183 PYMAP 169
P+ P
Sbjct: 1766 PHAMP 1770
>AK090458-1|BAC03439.1| 487|Homo sapiens FLJ00379 protein protein.
Length = 487
Score = 30.3 bits (65), Expect = 4.3
Identities = 12/28 (42%), Positives = 20/28 (71%)
Frame = +2
Query: 326 GDINKLAPIVTMPFLITYASIDYSYFAL 409
G +N LA +VT+ +L+ YA++D S +L
Sbjct: 38 GKLNTLAAVVTVFYLVAYAAVDLSCLSL 65
>AK024420-1|BAB15710.1| 540|Homo sapiens FLJ00009 protein protein.
Length = 540
Score = 30.3 bits (65), Expect = 4.3
Identities = 12/28 (42%), Positives = 20/28 (71%)
Frame = +2
Query: 326 GDINKLAPIVTMPFLITYASIDYSYFAL 409
G +N LA +VT+ +L+ YA++D S +L
Sbjct: 38 GKLNTLAAVVTVFYLVAYAAVDLSCLSL 65
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,810,151
Number of Sequences: 237096
Number of extensions: 1638296
Number of successful extensions: 8211
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 8053
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8197
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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