Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS304E04f
(521 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 205 5e-52
UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 157 1e-37
UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 156 3e-37
UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 155 8e-37
UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 142 4e-33
UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 128 8e-29
UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 121 9e-27
UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 109 5e-23
UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 97 2e-19
UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 97 3e-19
UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 95 1e-18
UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 92 8e-18
UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 89 8e-17
UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 88 1e-16
UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 87 2e-16
UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 86 5e-16
UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 85 9e-16
UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 82 7e-15
UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 81 2e-14
UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 80 3e-14
UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 79 6e-14
UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 78 1e-13
UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 77 2e-13
UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 75 8e-13
UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 75 8e-13
UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 75 1e-12
UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 75 1e-12
UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 74 2e-12
UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 73 5e-12
UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 71 1e-11
UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 71 1e-11
UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 71 1e-11
UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 71 2e-11
UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 71 2e-11
UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 71 2e-11
UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1... 70 3e-11
UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 70 3e-11
UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 70 3e-11
UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 70 3e-11
UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 69 5e-11
UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 69 5e-11
UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 69 5e-11
UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 69 9e-11
UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 69 9e-11
UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 69 9e-11
UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 68 1e-10
UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 68 2e-10
UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 67 2e-10
UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 67 2e-10
UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 66 3e-10
UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 66 3e-10
UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 66 5e-10
UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 66 6e-10
UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 65 1e-09
UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 65 1e-09
UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 64 2e-09
UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 64 2e-09
UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 61 2e-08
UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 60 3e-08
UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 60 4e-08
UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 60 4e-08
UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encep... 59 5e-08
UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 59 5e-08
UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 59 7e-08
UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 59 7e-08
UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 56 4e-07
UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 56 7e-07
UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 55 9e-07
UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 54 2e-06
UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 54 2e-06
UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 54 3e-06
UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 54 3e-06
UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 54 3e-06
UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 53 5e-06
UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 53 5e-06
UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intest... 51 2e-05
UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 51 2e-05
UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 51 2e-05
UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 50 3e-05
UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 49 6e-05
UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 49 6e-05
UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 49 7e-05
UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 48 1e-04
UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 46 7e-04
UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 46 7e-04
UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 45 0.001
UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 44 0.002
UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 44 0.002
UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 43 0.004
UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 43 0.004
UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 42 0.006
UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 42 0.011
UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1; ... 41 0.020
UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1; ... 41 0.020
UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 40 0.046
UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar... 39 0.060
UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 39 0.060
UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 38 0.11
UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 38 0.14
UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 36 0.43
UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2; Olig... 36 0.56
UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermopro... 36 0.56
UniRef50_Q2SJX8 Cluster: Outer membrane protein; n=1; Hahella ch... 35 0.98
UniRef50_Q8LIW5 Cluster: P0497A05.6 protein; n=6; Magnoliophyta|... 35 0.98
UniRef50_A7Q5W3 Cluster: Chromosome chr14 scaffold_54, whole gen... 35 1.3
UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 35 1.3
UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 35 1.3
UniRef50_O23714 Cluster: Proteasome subunit beta type-2-A; n=9; ... 34 1.7
UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 34 2.3
UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 33 3.0
UniRef50_Q6FB05 Cluster: Maf-like protein ACIAD1930; n=2; Acinet... 33 3.0
UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 33 4.0
UniRef50_Q980L4 Cluster: Proteasome subunit; n=4; Sulfolobaceae|... 33 4.0
UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 33 5.2
UniRef50_Q9U2Y8 Cluster: Putative uncharacterized protein fre-1;... 32 6.9
UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 32 6.9
UniRef50_Q83FM9 Cluster: Riboflavin synthase alpha chain; n=2; T... 32 9.2
UniRef50_A4AP76 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_A2GFB7 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_Q2FNX5 Cluster: Sensor protein; n=1; Methanospirillum h... 32 9.2
>UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69;
Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo
sapiens (Human)
Length = 246
Score = 205 bits (500), Expect = 5e-52
Identities = 91/145 (62%), Positives = 116/145 (80%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+YKYG EIPV +L +RIADISQVYTQNAEMRPLGC M+LI D+E GP YK DP+GYYC
Sbjct: 102 KYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYC 161
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
+KA AAG K + ++LEKK+K++ D + + ++ AI+CLS VLS+DFK SEIE+GVV+
Sbjct: 162 GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVT 221
Query: 159 KDNPKFRVLTETEIDRHLTAIAEKD 85
+NPKFR+LTE EID HL A+AE+D
Sbjct: 222 VENPKFRILTEAEIDAHLVALAERD 246
>UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15;
Eukaryota|Rep: Proteasome subunit alpha type-6-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 246
Score = 157 bits (381), Expect = 1e-37
Identities = 74/145 (51%), Positives = 101/145 (69%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ YG E+PV IL + IAD SQVYTQ+A MRPLG M++ D+E GP YK DP+G++
Sbjct: 102 RFTYGYEMPVDILAKWIADKSQVYTQHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFY 161
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
+KA +AG K + +LEKK+K + D+ +Q AIS L VL DFK++EIE+GVV
Sbjct: 162 GHKATSAGMKEQEAVNFLEKKMKENPSFTFDETVQTAISALQSVLQEDFKATEIEVGVVR 221
Query: 159 KDNPKFRVLTETEIDRHLTAIAEKD 85
+NP+FR LT EI+ HLTAI+E+D
Sbjct: 222 AENPEFRALTTEEIEEHLTAISERD 246
>UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9;
Bilateria|Rep: Proteasome subunit alpha type-6 -
Caenorhabditis elegans
Length = 246
Score = 156 bits (378), Expect = 3e-37
Identities = 66/145 (45%), Positives = 103/145 (71%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+YK G ++P +L +++AD++Q YTQNAEMR LGC+++ I+YDDE GP Y+ DP+GYY
Sbjct: 102 KYKNGYDMPCELLAKKMADLNQYYTQNAEMRSLGCALLFISYDDEKGPEVYRVDPAGYYR 161
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
K V+ G K + ++LEKK+K++ +L++ +AI+LAI L L +D +S ++E+ VV+
Sbjct: 162 GMKGVSVGVKQLPATSFLEKKIKKKSELTSTEAIELAIEALQTSLGIDVRSKDLEVVVVT 221
Query: 159 KDNPKFRVLTETEIDRHLTAIAEKD 85
KDN KF LT +++ HL IA +D
Sbjct: 222 KDNSKFTKLTSDQVEHHLNQIANRD 246
>UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha1 -
Cryptosporidium parvum Iowa II
Length = 252
Score = 155 bits (375), Expect = 8e-37
Identities = 74/144 (51%), Positives = 100/144 (69%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
++ G EIPV L +IAD++Q+YTQ+A MR LG S M I+ DDE GP YK DP+GY+ S
Sbjct: 109 FEKGVEIPVSYLSHKIADVNQLYTQHASMRLLGASGMFISIDDEDGPSLYKIDPAGYFAS 168
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSK 157
Y+A A G K +GN LEK +K S ++ I +I CL +L VDFK+ +IE+GVV+K
Sbjct: 169 YRACAVGTKEREGNNALEKIIKNEPLNSCEEVISASIDCLKTLLGVDFKAEDIEVGVVTK 228
Query: 156 DNPKFRVLTETEIDRHLTAIAEKD 85
D P+FR+L+ EID +LT IAE+D
Sbjct: 229 DMPEFRLLSVEEIDNYLTNIAERD 252
>UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome
undetermined scaffold_17, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 245
Score = 142 bits (344), Expect = 4e-33
Identities = 66/143 (46%), Positives = 93/143 (65%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
K G PV +L +R+AD++Q TQ +MR G +L YDDE GP YK DPSG+Y Y
Sbjct: 103 KNGYYCPVDVLSKRMADLAQTNTQYYQMRSYGVETILCQYDDELGPLLYKLDPSGHYSGY 162
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 154
KA A+G K + YLEK++K++ DL+ D+ I LAI L V+S DFK ++IE+G+V+K
Sbjct: 163 KATASGVKEQEAINYLEKQIKKKADLNYDETIMLAIQTLQNVISQDFKPTDIEVGIVTKQ 222
Query: 153 NPKFRVLTETEIDRHLTAIAEKD 85
+ KF LT ++D +L IA +D
Sbjct: 223 DKKFHKLTNEQVDHYLNLIANRD 245
>UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3;
Eukaryota|Rep: Proteasome subunit alpha type - Emiliania
huxleyi
Length = 264
Score = 128 bits (309), Expect = 8e-29
Identities = 69/156 (44%), Positives = 96/156 (61%), Gaps = 11/156 (7%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG---PCXYKTDPSG 349
++ G +IPV L +R AD +QVYTQ+A MRPLG +M++I D E P ++ DP+G
Sbjct: 102 KFNNGYDIPVSYLAKRAADTAQVYTQHANMRPLGIAMIIIGIDVEGEKKVPQLFRCDPAG 161
Query: 348 YYCSYKAVAAGAKTVDGNAYLEKKLKRRXD--------LSTDDAIQLAISCLSQVLSVDF 193
YY YKA +AGAK + N +LEK+ K LS DD +QLA++CL VL D
Sbjct: 162 YYVGYKATSAGAKEQEANNFLEKRFKPPAGSNVAVDPKLSHDDTVQLALACLQNVLGADL 221
Query: 192 KSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEKD 85
K+++IE VV DN F L+ E++ LTA+AE+D
Sbjct: 222 KANDIEACVVRHDNLAFTRLSADELETQLTALAERD 257
>UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 242
Score = 121 bits (292), Expect = 9e-27
Identities = 58/145 (40%), Positives = 93/145 (64%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
Q YG E+PV ++ ++ AD +Q+ TQ+A MRP G S M I +D+ +GP +++DP+G
Sbjct: 99 QLDYGYEMPVSLVAKKTADFAQMLTQHAYMRPFGVSSMFIGWDEVSGPQLWRSDPAGSVA 158
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
+++ AAG K + LEKK K +L+ D + A+ CL V S +FK+++IEI +V+
Sbjct: 159 AFRGCAAGEKEQEAFNNLEKK-KITKELTVDQVVCQALDCLQTVTSSEFKATDIEIAIVT 217
Query: 159 KDNPKFRVLTETEIDRHLTAIAEKD 85
KDN F +L++ EI+ +L +EKD
Sbjct: 218 KDNKLFHLLSQQEIEHYLVLASEKD 242
>UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3;
Piroplasmida|Rep: Proteasome subunit alpha type -
Theileria annulata
Length = 276
Score = 109 bits (261), Expect = 5e-23
Identities = 64/168 (38%), Positives = 93/168 (55%), Gaps = 24/168 (14%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
YKYG IP +L ++I+D++QVYTQ+A MR C+ ++++ + + GP YK D SG++
Sbjct: 109 YKYGINIPASVLCQKISDLNQVYTQHAYMRLHACTGLILSIEPDVGPKIYKFDSSGWFAG 168
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAI-------------------QLAISCLS 214
YKA GAK + LEK LKRR +S DA+ ++ I L
Sbjct: 169 YKACGIGAKEQESENALEKTLKRREAMSLQDAMKSNLHVNTEVHQLSQGQETKVTIEALR 228
Query: 213 QVLSVD-----FKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEKD 85
++ +D +S IE+ V SKDNP FR L+E EI+ +LT I E D
Sbjct: 229 CMIDIDAFTKGLGASSIEVAVASKDNPFFRQLSEEEIETYLTHITESD 276
>UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;
Eukaryota|Rep: Alpha 2 subunit of 20S proteasome -
Ostreococcus tauri
Length = 270
Score = 97.5 bits (232), Expect = 2e-19
Identities = 53/138 (38%), Positives = 76/138 (55%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y IPV L R A + Q +TQ +RP G S+++ YD E+GP Y+ DPSG Y ++K
Sbjct: 136 YKESIPVSQLVRETATVMQEFTQQGGVRPFGVSLLMAGYD-ESGPSLYQVDPSGSYFAWK 194
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A A G V+ +LEK+ D+ +DAI AI L + + IEIG+V D
Sbjct: 195 ASAIGKNMVNAKTFLEKRYS--DDIELEDAIHTAILTLKEGFDGQISADNIEIGIVGADR 252
Query: 150 PKFRVLTETEIDRHLTAI 97
KFR+L+ +EI +L +
Sbjct: 253 -KFRILSTSEIADYLEEV 269
>UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Ustilago maydis (Smut fungus)
Length = 305
Score = 96.7 bits (230), Expect = 3e-19
Identities = 46/115 (40%), Positives = 67/115 (58%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+YKYG I +L +R+A+++QVYTQ A MRP G SM+L+ D E GP +K DP+GYY
Sbjct: 99 KYKYGYAITPDLLAKRMANMNQVYTQRAAMRPYGVSMILVGIDAERGPQIFKIDPAGYYV 158
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIE 175
++A AAG K + +LEK+ K+ +T DA + + D + E E
Sbjct: 159 GFRATAAGVKQTEATNFLEKQFKKSSTTTTGDAASAVPEAPAGASATDAAALEAE 213
>UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 241
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/147 (34%), Positives = 85/147 (57%), Gaps = 2/147 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGP-CXYKTDPSGYY 343
+YK G IPV IL + +++ Q+ +Q +RP S +L D + YK +PSGY
Sbjct: 98 EYKQGFSIPVSILAQMLSERHQLESQLVYVRPSAVSAILFGLDGPSDSFALYKIEPSGYS 157
Query: 342 CSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAI-QLAISCLSQVLSVDFKSSEIEIGV 166
++AVA G K ++ + LEKK++ D T +A + +S L V VDF++ ++E+ +
Sbjct: 158 NGFRAVACGVKEIEAMSALEKKME---DFETPEATAEFTLSTLQTVCGVDFEAQDVEVSL 214
Query: 165 VSKDNPKFRVLTETEIDRHLTAIAEKD 85
+++DN KF L +++ L A+AEKD
Sbjct: 215 LTRDNSKFSKLPNDKVNEILHAVAEKD 241
>UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54;
Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo
sapiens (Human)
Length = 234
Score = 91.9 bits (218), Expect = 8e-18
Identities = 51/139 (36%), Positives = 77/139 (55%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y IP L +R+A + Q YTQ+ +RP G S+++ ++ E P +++DPSG Y ++K
Sbjct: 101 YQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWN-EGRPYLFQSDPSGAYFAWK 159
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A A G V+G +LEK+ DL +DAI AI L + IE+G+ ++
Sbjct: 160 ATAMGKNYVNGKTFLEKRYNE--DLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAG 217
Query: 150 PKFRVLTETEIDRHLTAIA 94
FR LT TE+ +L AIA
Sbjct: 218 --FRRLTPTEVKDYLAAIA 234
>UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48;
Eukaryota|Rep: Proteasome subunit alpha type-2 -
Drosophila melanogaster (Fruit fly)
Length = 234
Score = 88.6 bits (210), Expect = 8e-17
Identities = 50/138 (36%), Positives = 75/138 (54%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y IPV L +R+A + Q YTQ+ +RP G S+++ +D++ P Y++DPSG Y ++K
Sbjct: 101 YKEPIPVSQLVQRVATLMQEYTQSGGVRPFGVSLLICGWDNDR-PYLYQSDPSGAYFAWK 159
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A A G V+G +LEK+ DL DDA+ AI L + + IEIG+ D
Sbjct: 160 ATAMGKNAVNGKTFLEKRYSE--DLELDDAVHTAILTLKEGFEGKMTADNIEIGIC--DQ 215
Query: 150 PKFRVLTETEIDRHLTAI 97
F+ L I +L +I
Sbjct: 216 NGFQRLDPASIKDYLASI 233
>UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1;
Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha
subunit - Hyperthermus butylicus (strain DSM 5456 / JCM
9403)
Length = 243
Score = 87.8 bits (208), Expect = 1e-16
Identities = 49/140 (35%), Positives = 78/140 (55%), Gaps = 2/140 (1%)
Frame = -3
Query: 519 QYK--YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGY 346
QYK YG +IPV L R+I D+ Q+YTQ+ +RP G +++++ DD +GP + +PSG
Sbjct: 102 QYKFIYGEKIPVEYLTRQICDLMQLYTQHGGVRPFGVTLLIVGVDD-SGPKLFVAEPSGQ 160
Query: 345 YCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 166
Y SYKA G G A + + R D+ + AI L I ++ V+ +E+GV
Sbjct: 161 YMSYKAHGLGQG--GGQAIEILQREYRDDIDVEGAILLGIRAVASVMEGKPTPETLEVGV 218
Query: 165 VSKDNPKFRVLTETEIDRHL 106
+FR LT+ E+ +++
Sbjct: 219 ADTRTGRFRKLTKEELLKYI 238
>UniRef50_P23638 Cluster: Proteasome component Y13; n=3;
Saccharomycetaceae|Rep: Proteasome component Y13 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 258
Score = 87.0 bits (206), Expect = 2e-16
Identities = 43/100 (43%), Positives = 59/100 (59%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y +IPV IL RR++DI Q YTQ+ +RP G S + YDD G Y ++PSG Y +K
Sbjct: 102 YNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWK 161
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQ 211
A++ GA T L+ K D+ DDAI+LA+ LS+
Sbjct: 162 AISVGANTSAAQTLLQMDYK--DDMKVDDAIELALKTLSK 199
>UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 232
Score = 85.8 bits (203), Expect = 5e-16
Identities = 50/139 (35%), Positives = 75/139 (53%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
+ G E+P + + A Q YTQ +RP G S+++I ++ E GP ++ DPSG + ++
Sbjct: 98 RLGVEMPTREVVKHAAHKMQYYTQIGGVRPFGVSLLIIGWE-ELGPTLWQVDPSGTFWAW 156
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 154
KA A G ++ +LE++ D S DDAI AIS L + + IEIGVV +
Sbjct: 157 KATALGKRSDGSRTFLERRYSE--DQSVDDAIHTAISTLKEGFDGQLTAELIEIGVVD-E 213
Query: 153 NPKFRVLTETEIDRHLTAI 97
KFR L+ EI LT +
Sbjct: 214 TRKFRTLSTAEIRDFLTEV 232
>UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza
sativa|Rep: Proteasome subunit alpha type - Oryza sativa
subsp. japonica (Rice)
Length = 253
Score = 85.0 bits (201), Expect = 9e-16
Identities = 44/125 (35%), Positives = 75/125 (60%), Gaps = 1/125 (0%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG-PCXYKTDPSGYY 343
++K+G ++ +L + IAD +Q+ TQ+A++RP G M+ D+E G P + DP+G +
Sbjct: 115 RFKWGYKMSPCMLAQWIADRAQIRTQHAQIRPYGVVSMIFGIDEEKGTPELFTCDPAGQF 174
Query: 342 CSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVV 163
++KA +AG K + +LE+++K + LS+ LA S L VL DF + E E+G +
Sbjct: 175 FAHKATSAGPKEKEVMNFLEERMKSKPSLSSGTTKGLAKSALKHVLEGDFYAREFELGFI 234
Query: 162 SKDNP 148
K +P
Sbjct: 235 KKGDP 239
>UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29;
Archaea|Rep: Proteasome subunit alpha - Methanococcus
jannaschii
Length = 261
Score = 82.2 bits (194), Expect = 7e-15
Identities = 46/141 (32%), Positives = 81/141 (57%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG EI + +L ++I DI Q YTQ+ +RP G S +LIA D+ ++TDPSG YK
Sbjct: 104 YGEEISIEMLAKKICDIKQAYTQHGGVRPFGVS-LLIAGIDKNEARLFETDPSGALIEYK 162
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A A G+ LEK+ R D++ D+ ++LAI+ L++ + D K +++ +++ +
Sbjct: 163 ATAIGSGRPVVMELLEKEY--RDDITLDEGLELAITALTKA-NEDIKPENVDVCIITVKD 219
Query: 150 PKFRVLTETEIDRHLTAIAEK 88
+F+ + EI + + + +K
Sbjct: 220 AQFKKIPVEEIKKLIEKVKKK 240
>UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24;
Bilateria|Rep: Proteasome subunit alpha type-7 -
Carassius auratus (Goldfish)
Length = 251
Score = 80.6 bits (190), Expect = 2e-14
Identities = 49/138 (35%), Positives = 75/138 (54%)
Frame = -3
Query: 498 IPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAA 319
+ V + R IA + Q YTQ+ RP G S +++ +D + P Y+TDPSG Y ++KA A
Sbjct: 104 VTVEYITRYIATLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAI 163
Query: 318 GAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFR 139
G +LEK S +DAI+LAI L +V+ K+ IE+ V+ ++ P +
Sbjct: 164 GRSAKTVREFLEKNYTDEAIASDNDAIKLAIKALLEVVQSGGKN--IELAVIRRNQP-LK 220
Query: 138 VLTETEIDRHLTAIAEKD 85
+L EI+ L A EK+
Sbjct: 221 ILESKEIET-LVAEIEKE 237
>UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5;
Plasmodium|Rep: Proteasome subunit alpha, putative -
Plasmodium falciparum (isolate 3D7)
Length = 284
Score = 80.2 bits (189), Expect = 3e-14
Identities = 59/176 (33%), Positives = 81/176 (46%), Gaps = 32/176 (18%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSM------------------------ 409
Y G + L R I D QVYTQ+A MR CS
Sbjct: 109 YSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSNIYIYIYMNICTCVFIFLHKCVKCG 168
Query: 408 MLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQ-- 235
M+I D+ P +K DPSG+ Y+A G K + + LE+ L++R + I
Sbjct: 169 MIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDED 228
Query: 234 ------LAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAIAEKD 85
LAI L +L+ D K+SEIE+ +VS N F ++E EID +LT IAE+D
Sbjct: 229 IRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRNFTQISEKEIDNYLTYIAERD 284
>UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4;
Thermoplasmatales|Rep: Proteasome subunit alpha -
Picrophilus torridus
Length = 234
Score = 79.0 bits (186), Expect = 6e-14
Identities = 48/135 (35%), Positives = 71/135 (52%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YGS + + L +R+AD Q YTQ +RP G S++ D GP + DP+G YK
Sbjct: 103 YGSLMNIENLVKRVADQMQQYTQYGGVRPYGVSIIFAGLDS-IGPRLFDCDPAGTINEYK 161
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
V+ GA AYLEK+ K +LS D+AI++ I+ L ++ + E EI + K
Sbjct: 162 CVSIGAGKDQVTAYLEKEYKE--NLSEDEAIRMGIAALKSAVADESSMKEPEIASI-KMG 218
Query: 150 PKFRVLTETEIDRHL 106
F V T E+ ++L
Sbjct: 219 ETFHVFTSEEVSKYL 233
>UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like;
n=116; Eukaryota|Rep: Proteasome subunit alpha
type-7-like - Homo sapiens (Human)
Length = 256
Score = 77.8 bits (183), Expect = 1e-13
Identities = 43/137 (31%), Positives = 75/137 (54%)
Frame = -3
Query: 498 IPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAA 319
+ V + R IA + Q YTQ+ RP G S +++ +DD+ Y+TDPSG Y ++KA A
Sbjct: 110 VTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAI 169
Query: 318 GAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFR 139
G +LEK S +AI+LAI L +V+ K+ IE+ ++ ++ P +
Sbjct: 170 GRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGKN--IELAIIRRNQP-LK 226
Query: 138 VLTETEIDRHLTAIAEK 88
+ + E++ ++T I ++
Sbjct: 227 MFSAKEVELYVTEIEKE 243
>UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1;
Babesia bovis|Rep: Proteasome subunit alpha type 1 -
Babesia bovis
Length = 257
Score = 77.0 bits (181), Expect = 2e-13
Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 2/143 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ YG +I L IA SQ TQ + RP G +++ YDD G Y+T PSG
Sbjct: 96 KFLYGCDITATKLVSLIAQKSQANTQTSSKRPFGVGLLVAGYDDRTGLHLYETCPSGNVV 155
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD--FKSSEIEIGV 166
Y A A GA+ YLE+K+ + + D I A+ + + D F + + +
Sbjct: 156 EYNATAFGARCQSAKTYLERKIANFEECNIDSLIYHAVKAVKMTIPSDGEFDVDMVTVCI 215
Query: 165 VSKDNPKFRVLTETEIDRHLTAI 97
+ KD P F++LT E ++ +
Sbjct: 216 LGKDMP-FKLLTTAETQPYVDKV 237
>UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7;
Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum
aerophilum
Length = 243
Score = 75.4 bits (177), Expect = 8e-13
Identities = 44/141 (31%), Positives = 73/141 (51%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ Y I V L + + ++ Q YTQ RP G ++ LIA D G Y+TDPSG Y
Sbjct: 101 RFIYDEPIDVEFLTKAVCNLKQQYTQFGGARPFGVAL-LIAGVDRHGARLYQTDPSGVYI 159
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
Y A A GA++ +LEK K D+ + I+LA+ L+ + + S+ +E+ +
Sbjct: 160 GYFATAIGAESGTITEFLEKNYK--FDMEMGECIELALKALASAVEIT-DSANVEVAYAT 216
Query: 159 KDNPKFRVLTETEIDRHLTAI 97
+ K R +++ E+ LT +
Sbjct: 217 IEEKKMRKMSQDEVASLLTKL 237
>UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;
Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo
sapiens (Human)
Length = 261
Score = 75.4 bits (177), Expect = 8e-13
Identities = 45/146 (30%), Positives = 77/146 (52%), Gaps = 3/146 (2%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
+Y IP L + DI Q YTQ RP G S++ I +D G Y++DPSG Y +
Sbjct: 100 QYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGW 159
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSK 157
KA G + + L++ K +++ A+ LAI L++ + V S+E +EI +++
Sbjct: 160 KATCIGNNSAAAVSMLKQDYK-EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR 218
Query: 156 DNPK--FRVLTETEIDRHLTAIAEKD 85
+N K RVL + E+++ + E++
Sbjct: 219 ENGKTVIRVLKQKEVEQLIKKHEEEE 244
>UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2;
Sophophora|Rep: Proteasome subunit alpha type -
Drosophila melanogaster (Fruit fly)
Length = 289
Score = 74.9 bits (176), Expect = 1e-12
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 1/146 (0%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ Y +E PV L + + Q TQ + RP G +++ Y DE GP Y+ P+
Sbjct: 96 RHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGVGLLVAGY-DEQGPHIYQVMPTANVL 154
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVV 163
+ KA+A G+++ YLE+ ++ D D+ I AI + L S D ++ I + +V
Sbjct: 155 NCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAIRGSLGSDDVENLTINVAIV 214
Query: 162 SKDNPKFRVLTETEIDRHLTAIAEKD 85
KD P F++ TE E +++ + D
Sbjct: 215 GKDVP-FKMFTEAENQKYVKLVKAMD 239
>UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1;
Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit,
putative - Trypanosoma cruzi
Length = 179
Score = 74.5 bits (175), Expect = 1e-12
Identities = 42/138 (30%), Positives = 73/138 (52%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y +PV L R+I+ + Q +TQ+ +RP GCS+ L+A D G Y+ DPSG + ++K
Sbjct: 47 YHEPMPVSQLVRQISSLYQEFTQSGGVRPFGCSL-LVAGADSQGNHLYQVDPSGTFWAWK 105
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A + G + D +LEK+ ++ +DA+ A+ L + + ++G VS+
Sbjct: 106 ATSIGKGSTDAKTFLEKRYTN--EMEIEDAVHTALLTLKEGFDGTMTAENTQVGRVSEG- 162
Query: 150 PKFRVLTETEIDRHLTAI 97
KF + T ++ +L I
Sbjct: 163 -KFELFTVDQLKDYLDQI 179
>UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6;
Eukaryota|Rep: Proteasome subunit alpha type-1 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 73.7 bits (173), Expect = 2e-12
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 3/147 (2%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
Y Y S++ V L ++AD QV+TQ RP G +++ YD + G Y+T PSG +
Sbjct: 97 YVYESQMRVERLVTKVADKHQVHTQRYGRRPYGVGLLVAGYD-QLGAHIYQTCPSGNFYD 155
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL-SVD--FKSSEIEIGV 166
YK+++ G+++ YLEK + + + + I + L + + + D S + IG+
Sbjct: 156 YKSISIGSRSQSAKTYLEKHFESFEECTLEQLITHGLRALRETIPNTDDTLNSKNVSIGI 215
Query: 165 VSKDNPKFRVLTETEIDRHLTAIAEKD 85
V + P F+++ E + +L + ++
Sbjct: 216 VGEGQP-FKIIEEADAQPYLNLLENEE 241
>UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum
pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix
Length = 258
Score = 72.5 bits (170), Expect = 5e-12
Identities = 36/116 (31%), Positives = 61/116 (52%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG PV ++ + +AD+ Q YTQ+ +RP G +++ + + Y+TDP G Y S+K
Sbjct: 107 YGEPPPVELVAKVVADVKQAYTQHGGVRPFGVALIFAGVNPDGTTKVYRTDPGGQYFSFK 166
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVV 163
A+A G+ N EK R D+S ++A +LA+ L ++ + E I +
Sbjct: 167 AIAIGSGEQVANEMFEKHY--RSDMSLEEATKLALKILYAIIRKTVEDKEKAIATL 220
>UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6;
Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus
acidocaldarius
Length = 242
Score = 71.3 bits (167), Expect = 1e-11
Identities = 45/132 (34%), Positives = 61/132 (46%), Gaps = 2/132 (1%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y I + L + I+D+ Q YTQ+ +RP G ++++ D P T+PSG + Y
Sbjct: 105 YDEPISIEYLTKVISDVKQAYTQHGGVRPFGVALIVGGIDKGKQPKLLMTEPSGQFMPYY 164
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFK--SSEIEIGVVSK 157
AVA G YLEK K DL I LA+ L L K S +EIG
Sbjct: 165 AVAIGQGGYTATEYLEKNYKE--DLDIQSTILLALRALMATLKPGEKLNYSSVEIGYADV 222
Query: 156 DNPKFRVLTETE 121
D+ F+ LT E
Sbjct: 223 DSGTFKKLTTEE 234
>UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8;
Halobacteriaceae|Rep: Proteasome subunit alpha 1 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 71.3 bits (167), Expect = 1e-11
Identities = 45/138 (32%), Positives = 66/138 (47%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
Q +YG + V L + I D Q YTQ RP G ++ +I P ++TDPSG
Sbjct: 102 QLRYGEPVGVETLTKEITDYIQQYTQVGGARPFGVAL-IIGGIVNGEPRLFETDPSGTPY 160
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
+KA+A GA D YLE+ DL D+ + LA++ L+ V + I + V
Sbjct: 161 EWKALAVGADRGDIRDYLEEHYDEGMDL--DEGVDLALAALASVNDDELSPEGIGVATVD 218
Query: 159 KDNPKFRVLTETEIDRHL 106
+ F LT+ E + HL
Sbjct: 219 VETETFGQLTDEEKEAHL 236
>UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4;
Eukaryota|Rep: Proteasome subunit alpha type-4 -
Dictyostelium discoideum (Slime mold)
Length = 250
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 4/138 (2%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
Y+Y +PV L +I D Q YTQ +RP G S + +D G Y++DPSG +
Sbjct: 100 YQYQEPMPVEQLVSQICDTKQGYTQYGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAG 159
Query: 336 YKAVAAGAKTVD-GNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLS-VDFKSSEIEIGVV 163
+KA + G + + L K D+S +A+QLA+ L++ + + S ++E
Sbjct: 160 WKATSIGGENSQVAQSVLRSNYK--PDISLKEALQLALKVLTKTMDRSNINSEKLEFSYF 217
Query: 162 SK--DNPKFRVLTETEID 115
+K DN + + T E+D
Sbjct: 218 TKQGDNVVYHIFTAAELD 235
>UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia
intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia
ATCC 50803
Length = 250
Score = 70.9 bits (166), Expect = 2e-11
Identities = 44/148 (29%), Positives = 75/148 (50%), Gaps = 13/148 (8%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIA------YDDEAGP------CX 370
++ +PV++L R IA Q YTQ +RP GCS++L ++ EA
Sbjct: 100 EFQESMPVNMLARDIASTMQEYTQRGGVRPFGCSVLLAGKSMATEHETEANGSRINPYIL 159
Query: 369 YKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFK 190
Y+ D SG Y ++KA A G ++ +LEK+ +S D I + ++CL + + D
Sbjct: 160 YQVDSSGSYYTWKACANGNQSSQARDFLEKRYNE--SVSISDGILIGLTCLHEYVDGDID 217
Query: 189 SSEIEIGVVSKD-NPKFRVLTETEIDRH 109
+EIG++ + +FR+L EI+ +
Sbjct: 218 GKTVEIGIIGDETGGQFRLLAADEINTY 245
>UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9;
Eukaryota|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 271
Score = 70.5 bits (165), Expect = 2e-11
Identities = 42/149 (28%), Positives = 72/149 (48%), Gaps = 5/149 (3%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
QY YG E PV L +I D Q YTQ +RP G S + YD G Y++DPSG +
Sbjct: 108 QYTYGEEQPVEQLVTQICDRKQSYTQFGGLRPFGVSFLFAGYDKNYGYQLYQSDPSGNFS 167
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVV 163
+KA A G + L+++ DL+ + + L L++ + +++ E ++
Sbjct: 168 GWKATAIGQNNQTATSLLKQEWNE--DLTLEQGLHLVAKVLTKTMDTTSPTADKFEFSIL 225
Query: 162 SKDNP----KFRVLTETEIDRHLTAIAEK 88
+ +N ++L+E EI L + ++
Sbjct: 226 THNNESNKCSQKILSEKEIGELLEKVQKE 254
>UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7;
n=3; Ascomycota|Rep: Probable proteasome subunit alpha
type-7 - Schizosaccharomyces pombe (Fission yeast)
Length = 259
Score = 70.5 bits (165), Expect = 2e-11
Identities = 40/113 (35%), Positives = 62/113 (54%), Gaps = 1/113 (0%)
Frame = -3
Query: 498 IPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYD-DEAGPCXYKTDPSGYYCSYKAVA 322
+ + L R +A + Q YTQ+ +RP G S ++ +D + P Y+T+P+G Y ++KA A
Sbjct: 103 VSIEYLTRYVAGVQQKYTQSGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATA 162
Query: 321 AGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVV 163
G + YLEK K LS D+ I LA+S L +V V S IE+ ++
Sbjct: 163 IGRASKAAREYLEKNWKE--GLSRDETIHLAVSSLLEV--VQTASGNIELAIM 211
>UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1;
Homo sapiens|Rep: Proteasome alpha 6 subunit variant -
Homo sapiens (Human)
Length = 80
Score = 70.1 bits (164), Expect = 3e-11
Identities = 27/61 (44%), Positives = 43/61 (70%)
Frame = -3
Query: 411 MMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQL 232
M+LI D+E GP YK DP+GYYC +KA AAG K + ++LEKK+K++ D + + +++
Sbjct: 9 MILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVEV 68
Query: 231 A 229
+
Sbjct: 69 S 69
>UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;
n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta
subunit - Cenarchaeum symbiosum
Length = 245
Score = 70.1 bits (164), Expect = 3e-11
Identities = 44/141 (31%), Positives = 67/141 (47%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y + V + + +AD Q +TQ A +RP G ++++ DD + TDPSG Y SY
Sbjct: 102 YDESVEVEAVAKHLADQCQQFTQYAGVRPFGVALIIGGVDDGGKGQLFLTDPSGTYISYD 161
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A+A GA + +LEK K S +DA LA + + S I + VS DN
Sbjct: 162 AIAIGAGSEQVTEFLEKSYKPG---SMEDAAVLAAAAIRIAGEETDTESHIRMARVSADN 218
Query: 150 PKFRVLTETEIDRHLTAIAEK 88
+F ++ + E+ A K
Sbjct: 219 RRFEMVPDGEVASFAAKAAAK 239
>UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8;
Euryarchaeota|Rep: Proteasome subunit alpha -
Methanococcus maripaludis
Length = 259
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/141 (28%), Positives = 71/141 (50%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG I V L ++I DI Q YTQ+ RP G ++++ D + ++TDPSG YK
Sbjct: 105 YGEAITVEALAKKICDIKQAYTQHGGARPFGLALLITGIDRHSAR-LFETDPSGALIEYK 163
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A A G+ LE K +++ + ++LA+ LS+ + + K I++ ++
Sbjct: 164 ATAIGSGRPIAMEVLESKYDE--NMTVSEGMELALYALSKT-TEELKPENIDMAIIKDSG 220
Query: 150 PKFRVLTETEIDRHLTAIAEK 88
++ EI++ + A+ EK
Sbjct: 221 KLVEKISVDEIEKIVKAVYEK 241
>UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;
core eudicotyledons|Rep: Proteasome subunit alpha
type-1-A - Arabidopsis thaliana (Mouse-ear cress)
Length = 278
Score = 70.1 bits (164), Expect = 3e-11
Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 1/136 (0%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
+ Y S +PV L +AD +QV TQ + RP G + L+ DE+G Y PSG Y
Sbjct: 97 FTYESPLPVGRLVVHLADKAQVCTQRSWKRPYGVGL-LVGGLDESGAHLYYNCPSGNYFE 155
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVS 160
Y+A A G+++ YLE++ + D S +D I+ AI + + L + KSS + ++
Sbjct: 156 YQAFAIGSRSQAAKTYLERRFESFGDSSREDLIKDAILAVRETLQGETLKSSLCTVAILG 215
Query: 159 KDNPKFRVLTETEIDR 112
D P F L + I +
Sbjct: 216 VDEP-FHFLDQEAIQK 230
>UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 288
Score = 69.3 bits (162), Expect = 5e-11
Identities = 43/145 (29%), Positives = 72/145 (49%), Gaps = 2/145 (1%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
+ Y S IP++ L R+ SQV TQ RP G ++L +D E+GP ++T PSG
Sbjct: 126 FTYDSPIPLNTLVNRLVLKSQVNTQEYGRRPFGVGLLLAGFD-ESGPHLFETCPSGNCFE 184
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLS--VDFKSSEIEIGVV 163
Y ++A G+++ YLEK K + S D I + L LS + +++ ++
Sbjct: 185 YYSIAIGSRSQASKTYLEKHFKEFANCSKDQLILHTLRALRSSLSSEQEMNQENVDVAIL 244
Query: 162 SKDNPKFRVLTETEIDRHLTAIAEK 88
+ N + L E E ++L I ++
Sbjct: 245 GR-NDIYNELLEEEKIKYLQIINQE 268
>UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2;
Eukaryota|Rep: Proteasome subunit alpha type-5 -
Entamoeba histolytica
Length = 247
Score = 69.3 bits (162), Expect = 5e-11
Identities = 43/149 (28%), Positives = 77/149 (51%), Gaps = 5/149 (3%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEM-----RPLGCSMMLIAYDDEAGPCXYKTDP 355
++ Y I V ++ + I+D+S + + + RP G ++ LIA DE GP ++TDP
Sbjct: 100 RFMYDEPINVEVVAQAISDLSLRFGEGSRKKKVMSRPFGVAL-LIAGVDETGPRLFQTDP 158
Query: 354 SGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIE 175
SG + + A A GA T + L +K + ++ +A LA+S L QV+ S +E
Sbjct: 159 SGMFIEFYAKATGAGTEAAQSILHEKYNK--SMTLREAEILALSTLKQVMEEKLNSKNVE 216
Query: 174 IGVVSKDNPKFRVLTETEIDRHLTAIAEK 88
+ +V+ + KF ++ I+ + I E+
Sbjct: 217 VALVTVEKKKFEIMDTAFIENLIGEIKEE 245
>UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4;
n=5; Eukaryota|Rep: Probable proteasome subunit alpha
type-4 - Schizosaccharomyces pombe (Fission yeast)
Length = 248
Score = 69.3 bits (162), Expect = 5e-11
Identities = 37/127 (29%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+ E+P L RR+ D+ Q YTQ +RP G S + +D G ++++PSG Y S++
Sbjct: 101 FNEEMPCEQLVRRVCDLKQGYTQYGGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQ 160
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSKD 154
A + G + + + ++ K D++ D+A +A+ LS+ L S +IE ++KD
Sbjct: 161 ANSIGGNSTSVQSLMRQEYK--DDINLDEASAMAVKFLSKTLDSNSLTHEKIEFATITKD 218
Query: 153 NPKFRVL 133
K +++
Sbjct: 219 TTKNKMV 225
>UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia
intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia
ATCC 50803
Length = 247
Score = 68.5 bits (160), Expect = 9e-11
Identities = 44/144 (30%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG-PCXYKTDPSGYYCS 337
K+ + IL R+ADI+Q+YTQ A RP G + +D E +KTDP+G
Sbjct: 102 KWNYQPTADILCTRLADINQIYTQEAWQRPFGNIAVFAGWDPEQDRSLLFKTDPAGTNTG 161
Query: 336 YKAVAAGAKTV---DGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 166
Y A+A G K V D K ST + A+ V+S ++E+ +
Sbjct: 162 YFAIAVGVKEVELADALTVQVKSFPNGICESTQKGLDCALKIFQNVISTGLTGDDVEVAI 221
Query: 165 VSKDNPKFRVLTETEIDRHLTAIA 94
+K + LT E+DR L +A
Sbjct: 222 YTKTG--LKRLTPIEVDRRLGELA 243
>UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_32,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 68.5 bits (160), Expect = 9e-11
Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+Y++ I + L I D Q TQ RP G + + YD + G + TDPSG Y
Sbjct: 98 RYQFQDNIALEQLIINICDYKQNKTQVGGQRPFGTAFLFAGYDKKNGFQLFSTDPSGNYA 157
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDF-KSSEIEIGVV 163
+KA A G + N+YL++ K +L+ + + +AI L + + + S+IEI V+
Sbjct: 158 GWKATAIGKNNLAANSYLKQDYKE--NLTLEQGLDIAIKALVKTMDTSSPQPSKIEIVVI 215
Query: 162 SKDNPKFRVLTETE 121
S+ + + T E
Sbjct: 216 SQQGKEVKSKTYNE 229
>UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4;
Saccharomycetales|Rep: Proteasome component Y7 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 178
Score = 68.5 bits (160), Expect = 9e-11
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPC-XYKTDPSGYYCSY 334
Y PV I+ + IA + Q TQ+ +RP G S+++ YD+ Y+ DPSG Y +
Sbjct: 29 YNEYPPVRIMVQEIAKVMQESTQSGGIRPFGVSLLVGGYDEYLDKFQLYQVDPSGSYFPW 88
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 154
KA A G + +LEK+ +L +DAI +A+ L + + + ++I V+S
Sbjct: 89 KATAIGKTSNSAKTFLEKRWNE--NLQLEDAIHVALLALKESVDGELIGENLDIAVISDP 146
Query: 153 NPKFRVLTETEID 115
+ T T ++
Sbjct: 147 QQQLLGFTGTNLE 159
>UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2;
Giardia intestinalis|Rep: Proteasome subunit alpha type
- Giardia lamblia ATCC 50803
Length = 214
Score = 68.1 bits (159), Expect = 1e-10
Identities = 38/107 (35%), Positives = 63/107 (58%)
Frame = -3
Query: 492 VHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGA 313
V I+ + +A I Q +T RP G S++L A +D G + DPSG Y +KA+A G
Sbjct: 106 VEIIAKAVASILQSHTHRGGTRPFGVSIIL-AGNDLNGSHVFMCDPSGVYTEWKALAIGN 164
Query: 312 KTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 172
+ V +LEKKLK +T+DA+ LA + LS+++ V+ ++ + ++
Sbjct: 165 QCVTIIEFLEKKLKEGEPQNTNDALSLAKAALSELIDVNDETFQCKV 211
>UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 266
Score = 67.7 bits (158), Expect = 2e-10
Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 1/131 (0%)
Frame = -3
Query: 450 YTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLK 271
YTQ+ RP G S +++ +D + P Y+TDP+G Y S+KA A G +LEK
Sbjct: 132 YTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWKANAIGRSAKTVREFLEKHYS 191
Query: 270 RRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLTAI-A 94
S + ++LA+ L +V+ K+ IE+ V+ + P ++ +E+++++T I
Sbjct: 192 DEVVESESETVKLAVRALLEVVQSGAKN--IELAVMRRGEP-LKMYEVSEVEKYVTEIEK 248
Query: 93 EKD*G*IKSKQ 61
EK+ K KQ
Sbjct: 249 EKEEEAEKKKQ 259
Score = 50.0 bits (114), Expect = 3e-05
Identities = 21/56 (37%), Positives = 34/56 (60%)
Frame = -3
Query: 498 IPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+ V + R +A + Q YTQ+ RP G S +++ +D + P Y+TDP+G Y S+K
Sbjct: 75 VTVEYITRFMAQLKQRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWK 130
>UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome
(prosome macropain) subunit alpha type 4; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Proteasome (prosome macropain) subunit alpha type 4 -
Strongylocentrotus purpuratus
Length = 257
Score = 67.3 bits (157), Expect = 2e-10
Identities = 43/146 (29%), Positives = 73/146 (50%), Gaps = 3/146 (2%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
+Y IP L + DI Q YTQ RP G S++ + +D G Y++DPSG Y +
Sbjct: 100 QYQENIPNEQLVSTLCDIKQFYTQAGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGW 159
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSK 157
KA G + + L+++ K D A+ LA+ LS+ L + + E IEI +++
Sbjct: 160 KATCIGNNSAAAISMLKQEYK-EGDTDLKGALALAVKVLSKTLDMTKVTPEKIEIASLTR 218
Query: 156 DN--PKFRVLTETEIDRHLTAIAEKD 85
++ K R+L E+ + + E++
Sbjct: 219 EDGKTKIRILPVEELQKLIKEHEERE 244
>UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5;
Magnoliophyta|Rep: Proteasome subunit alpha type-4 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 250
Score = 67.3 bits (157), Expect = 2e-10
Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
+ Y +PV L + + D Q YTQ +RP G S + +D G Y +DPSG Y
Sbjct: 99 FMYQEPMPVEQLVQSLCDTKQGYTQFGGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGG 158
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVV 163
+KA A GA + L++ K D + ++A++LA+ L++ + S S ++E+ V
Sbjct: 159 WKAAAVGANNQAAQSILKQDYK--DDATREEAVELALKVLTKTMDSTSLTSEKLELAEV 215
>UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative;
n=2; Theileria|Rep: Proteasome subunit alpha type 1,
putative - Theileria parva
Length = 252
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ YG +I L +++ SQ TQ + RP G +++ YD+ G ++T PSG
Sbjct: 96 RFLYGCDITASQLVSLVSEKSQANTQVSSKRPFGVGLLVAGYDETTGLHLFETCPSGNVV 155
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD--FKSSEIEIGV 166
+ A A GA+ YLE+K+ + + I AI L + D F I +GV
Sbjct: 156 EFNATAFGARCQSAKTYLERKIVNFSESDLNGLIYHAIKALKTTIPNDGEFDVDVISVGV 215
Query: 165 VSKDNP 148
V K P
Sbjct: 216 VGKGTP 221
>UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep:
Yarrowia lipolytica chromosome C of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 289
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 2/136 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
Q Y + V IAD +Q TQ RP G +++I + DEAGP Y+ PSG
Sbjct: 95 QMVYKRPLAVSRAVYAIADKAQGNTQQYGRRPYGVGLLIIGH-DEAGPHLYEFLPSGSAL 153
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD--FKSSEIEIGV 166
Y+ A GA++ YLEKK DLS ++ I ++ L L+ D I
Sbjct: 154 EYRGAAIGARSQAARTYLEKKFDTFPDLSLEELIVEGLNALRDTLAQDKELTLKNTSIAY 213
Query: 165 VSKDNPKFRVLTETEI 118
V KD P F +L + ++
Sbjct: 214 VGKDTP-FTLLDDDKV 228
>UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4;
Oryza sativa|Rep: Proteasome subunit alpha type-1 -
Oryza sativa subsp. japonica (Rice)
Length = 270
Score = 66.1 bits (154), Expect = 5e-10
Identities = 38/121 (31%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
+ Y + +PV L R+AD +QV TQ + RP G + L+A DE+G Y PSG Y
Sbjct: 97 FVYDAPLPVSRLALRLADKAQVCTQRSWKRPYGVGL-LVAGLDESGAHLYYNCPSGNYFE 155
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVS 160
Y+A A G+++ +LE++ + D + + I+ A+S + + L + SS + +V
Sbjct: 156 YQAFAIGSRSQAAKTFLERRFEGYNDYTPEQLIKDALSAIKETLQGEKLTSSNCTVAIVG 215
Query: 159 K 157
+
Sbjct: 216 R 216
>UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like,
putative; n=5; Oligohymenophorea|Rep: Proteasome subunit
alpha type 7-like, putative - Tetrahymena thermophila
SB210
Length = 242
Score = 65.7 bits (153), Expect = 6e-10
Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 2/115 (1%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y +P++ + R IA + Q YTQ + RP G S ++ +D + P ++TDPSG +K
Sbjct: 98 YDDRVPINYIARYIASVQQKYTQKSGARPFGISTLVGGFDSKGQPRLFQTDPSGACTEWK 157
Query: 330 AVAAG--AKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 172
AVA G KTV N LEK + L+ + ++LA L +V+ K+ E+ +
Sbjct: 158 AVALGKHRKTVMEN--LEKNYQEEY-LAEEKCLELACRVLLEVVQSGCKNIELVV 209
>UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei rhodesiense
Length = 266
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+Y + S+ P+ +L + Q + Q A RP G +++ YD + GP Y+T PSG
Sbjct: 97 RYMHDSDAPLVMLADIVGAKHQRHIQFAGKRPFGVGLLIAGYDRQ-GPRLYQTVPSGDVF 155
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLS--VDFKSSEIEIGV 166
+KA A G ++ YLE+ + D+ + A+ L S V+ I +
Sbjct: 156 DFKATAMGLRSQAARTYLERHFRGFPACDLDELVMHALRALGAATSGGVELNIKNTTIAI 215
Query: 165 VSKDNPKFRVLTETEIDRHL 106
V K P F +LTE E ++L
Sbjct: 216 VGKGTP-FTILTEEEARKYL 234
>UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1
- Homo sapiens (Human)
Length = 263
Score = 64.9 bits (151), Expect = 1e-09
Identities = 35/146 (23%), Positives = 72/146 (49%), Gaps = 2/146 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ + +PV L I +Q+ TQ RP G +++ Y D+ GP ++T PS Y
Sbjct: 96 RFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGY-DDMGPHIFQTCPSANYF 154
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSV--DFKSSEIEIGV 166
+A++ GA++ YLE+ + + + ++ ++ + L + L D + + IG+
Sbjct: 155 DCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQDLTTKNVSIGI 214
Query: 165 VSKDNPKFRVLTETEIDRHLTAIAEK 88
V KD +F + + ++ L + E+
Sbjct: 215 VGKD-LEFTIYDDDDVSPFLEGLEER 239
>UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 233
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/136 (32%), Positives = 66/136 (48%), Gaps = 1/136 (0%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+G+EI V L +A SQ T RP G +++I + GP ++T PSG + Y
Sbjct: 99 FGTEIRVADLADTVALQSQKKTSKVGKRPYGVGLLMIGAGVD-GPRLFETCPSGQHWEYN 157
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKD 154
A A G + YLE L D + D I+ A+ L+ S + S E I +GVV D
Sbjct: 158 AQAIGRRAQAAKTYLETNLNEFPDCTRDQLIRHALRALNDCKSRESDSLEAIALGVVGID 217
Query: 153 NPKFRVLTETEIDRHL 106
P F +L E+ +++
Sbjct: 218 EP-FTILEGPELQKYI 232
>UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7;
Aconoidasida|Rep: Proteasome subunit alpha type -
Plasmodium yoelii yoelii
Length = 278
Score = 63.7 bits (148), Expect = 2e-09
Identities = 33/127 (25%), Positives = 68/127 (53%)
Frame = -3
Query: 495 PVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAG 316
PV + + +A I Q +T +RP G + ++ + + C Y+T+PSG Y S+KA A G
Sbjct: 140 PVDYIAKYVARIQQKFTHRGGVRPFGIATLITGFKNNKEICIYQTEPSGIYASWKAQAIG 199
Query: 315 AKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRV 136
+LEK + ++ ++ + LA+ + +V V+ S +E+ +++++ K+
Sbjct: 200 KNAKVVQEFLEKNYQE--NMEKNECLLLALKAIFEV--VELSSKNVELALLTEEELKY-- 253
Query: 135 LTETEID 115
+ E E++
Sbjct: 254 IDEQEVN 260
>UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7;
Trypanosomatidae|Rep: Proteasome subunit alpha type -
Leishmania major
Length = 285
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/122 (28%), Positives = 61/122 (50%), Gaps = 1/122 (0%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
QY + I + L R + D Q+YTQ +RP G S +L+ +D G Y T+PSG Y
Sbjct: 104 QYTFQEPIAIEDLCRILCDEKQLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYS 163
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVV 163
++ A A G ++ L+K +++ +D + LA+ L + + + +E+ V+
Sbjct: 164 AWSAYAIGQNDQVAHSLLKKDW--HENMTLEDGMLLALRVLGKTMDTAKIDLGRVEVAVM 221
Query: 162 SK 157
K
Sbjct: 222 RK 223
>UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:
NEQ521 - Nanoarchaeum equitans
Length = 250
Score = 60.1 bits (139), Expect = 3e-08
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 3/144 (2%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+Y YG I + L + IADI Q YTQ +RP G S++ DD G + T+P G +
Sbjct: 104 KYFYGHPIDIRGLVKEIADIKQEYTQIGGVRPFGVSIIFAGIDD-TGKHIFVTEPGGMFW 162
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL---SVDFKSSEIEIG 169
YK G YL K+ +LS AI+L + L + + + +++I
Sbjct: 163 EYKLAVIGEGEQKVLDYLGKEYNE--NLSLKKAIELGLKALYNFYKENNNELTAEKLDIA 220
Query: 168 VVSKDNPKFRVLTETEIDRHLTAI 97
V + K + + EI++ L I
Sbjct: 221 YVDEKTKKAKYVDVNEIEKILEKI 244
>UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia
intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia
ATCC 50803
Length = 244
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y IPV +L + I+D+ Q YT + +RP G S + +D G Y+TDPSG Y ++
Sbjct: 99 YDEPIPVEVLVQYISDVKQNYTHHGGLRPYGVSFLFGGWDAHLGFQLYQTDPSGNYSAWV 158
Query: 330 AVAAGAKTVDGNAYLEKKL-KRRXDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSK 157
A + G + + L++ + + +A Q A+S L + + SS+ +EI V K
Sbjct: 159 ATSIGGSAPEIASALKQNIADSSQKILLKEAQQYAVSALIKTTDITKVSSDKMEILTVVK 218
>UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4;
Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN -
Encephalitozoon cuniculi
Length = 232
Score = 59.7 bits (138), Expect = 4e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 5/142 (3%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEM-----RPLGCSMMLIAYDDEAGPCXYKTDPS 352
+ YG I V L + ++ +S + + E RP G S+++ +D E P Y DPS
Sbjct: 97 HMYGENISVERLLKYLSSLSLRFGEEDEAKMIFRRPFGVSLIIAGFDTE--PRLYSLDPS 154
Query: 351 GYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 172
G Y SYKA A G+ LE + + L D +++ + LS+V+ +E+
Sbjct: 155 GSYISYKAKAIGSGHEVVEGILENEYEEYSGL--DQSLRKVLCTLSKVMKDKISKDNVEV 212
Query: 171 GVVSKDNPKFRVLTETEIDRHL 106
VV+++ KF LT E+ +L
Sbjct: 213 VVVTQEESKF--LTPEEVSVYL 232
>UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1;
Encephalitozoon cuniculi|Rep: 20S PROTEASOME COMPONENT
C3 - Encephalitozoon cuniculi
Length = 233
Score = 59.3 bits (137), Expect = 5e-08
Identities = 36/140 (25%), Positives = 66/140 (47%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG V + + + Q YTQ + RP G ++M+ A P Y+ DPSG Y +
Sbjct: 99 YGRYPDVDVFTAHFSSVVQEYTQKSGYRPFG-TLMIFAGPVRGVPRLYQVDPSGSYQTAD 157
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A+G D ++E++L+ DD I +S + + + ++ +++IGV K
Sbjct: 158 VCASGVGYSDARKFVERRLE-----GLDDNIVNCVSSIREFAGKEVRAKDLDIGVYYKTE 212
Query: 150 PKFRVLTETEIDRHLTAIAE 91
F+ T EI+ ++++
Sbjct: 213 NIFKAFTLDEIEEVFDSLSK 232
>UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT
C6 - Encephalitozoon cuniculi
Length = 234
Score = 59.3 bits (137), Expect = 5e-08
Identities = 42/143 (29%), Positives = 66/143 (46%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCS 337
+ +G E+ IL R AD Q Q++ R + + +D E P Y+TD SG
Sbjct: 96 FSFGFEVTPDILCRSFADKVQQLIQSSAERSAAFNASIFGFDKER-PMIYQTDMSGISYP 154
Query: 336 YKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSK 157
A AAG K ++EK R D+ + ++A+ L + + D SE+E+ + K
Sbjct: 155 CYATAAGEKHGKMTKFIEKNY--RSDIDDKELFEVAVGALLESIGADSGCSEVEVAYL-K 211
Query: 156 DNPKFRVLTETEIDRHLTAIAEK 88
L+ E+D+ L IAEK
Sbjct: 212 VGQDLCHLSAKEVDKILQDIAEK 234
>UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 251
Score = 58.8 bits (136), Expect = 7e-08
Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 2/134 (1%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG+ IP+ +L RIA +T +RP GCS++L D + G Y PSG Y
Sbjct: 103 YGNPIPIRVLAERIAMYMHNFTLYGSVRPFGCSILLGGLDQDRGVELYCIHPSGSCYKYC 162
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVSKD 154
A+A G LEK +++ +LS +DA+ A + Q K+ E+E+ +
Sbjct: 163 AMAVGKGRQFARTDLEKLMEK--NLSEEDALYEAARVIIQSREEGASKNLELEMAFIGPG 220
Query: 153 NP-KFRVLTETEID 115
+ +F ++ E +I+
Sbjct: 221 SDFQFSIVPEKQIN 234
>UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3;
Basidiomycota|Rep: Proteasome subunit alpha type -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 299
Score = 58.8 bits (136), Expect = 7e-08
Identities = 36/115 (31%), Positives = 52/115 (45%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG PV L + IAD +Q TQ RP G ++I DE GP ++ P+G Y
Sbjct: 99 YGRATPVARLVQSIADRAQTNTQEYGRRPYGVGFLVIG-KDETGPHLFEFSPAGTAFEYY 157
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 166
A + GA++ YLEK + S ++ I +S L L D S + +
Sbjct: 158 AHSIGARSQSAKTYLEKNYHLFPNASLEELINHGLSALHDTLQQDKHLSSLNTSI 212
>UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 238
Score = 56.4 bits (130), Expect = 4e-07
Identities = 33/117 (28%), Positives = 57/117 (48%)
Frame = -3
Query: 498 IPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAA 319
IP+ + R IA + YTQ+ +RP G + ++ +D P Y+T PSG +KA
Sbjct: 102 IPIENIARYIATVQLTYTQSGGVRPFGVTTLICGFDPLDKPHIYETLPSGILSEWKARGI 161
Query: 318 GAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNP 148
G Y+EK +LS DD ++ I L ++ D + +E+ ++ ++P
Sbjct: 162 GRFGHPVQEYIEKYYV--DNLSEDDVKRITIGSLREI--ADCRPKNMEVAIMKPNSP 214
>UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13;
Eukaryota|Rep: Proteasome subunit alpha type-7 -
Trypanosoma brucei brucei
Length = 247
Score = 55.6 bits (128), Expect = 7e-07
Identities = 37/141 (26%), Positives = 71/141 (50%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y I V +L R +A + Q TQ++ RP G S ++ +++ P +KT+PSG ++
Sbjct: 98 YEDAIDVDLLVRYVARVQQRSTQSSGSRPYGVSTIIGGFNENGQPQLWKTEPSGTSSAWN 157
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDN 151
A A G ++EK + ++ D + AI L + +V+ S IE+ V+ +
Sbjct: 158 AAAIGRNDKVVLEFMEKNY--QDGMTRDRCVHFAIKALLE--AVESGSKNIELLVLERG- 212
Query: 150 PKFRVLTETEIDRHLTAIAEK 88
K +++TE+ R + + ++
Sbjct: 213 -KAAYMSDTELHRFVVEVEKE 232
>UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 283
Score = 55.2 bits (127), Expect = 9e-07
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 14/109 (12%)
Frame = -3
Query: 387 EAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQV 208
+ GP Y+ DPSG Y +KA A G +LEK+ +L +DA+ +A+ L +
Sbjct: 175 KGGPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYTEGLEL--EDAVHIALLTLKET 232
Query: 207 LSVDFKSSEIEIGVV--------------SKDNPKFRVLTETEIDRHLT 103
+ + IEIG+V P+FR L+ EI+ +LT
Sbjct: 233 IEGEMNGDSIEIGIVGPPADHLLGVEGVEGAQGPRFRKLSPQEIEDYLT 281
>UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Chaetomium globosum (Soil fungus)
Length = 267
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/105 (29%), Positives = 50/105 (47%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+G +PV L I +Q+ TQ+ RP G +++ DD GP ++ PSG
Sbjct: 99 FGRSMPVRTLVEIIGSKAQINTQHYGKRPYGVGLLVAGVDDH-GPHLFEFQPSGMTEEMV 157
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD 196
A A GA++ YLEK + + D ++ I+ + L + L D
Sbjct: 158 AFAIGARSQMARTYLEKNIDKFADCDREELIRHGLRALKESLVQD 202
>UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16;
Drosophila|Rep: Proteasome subunit alpha type-7-1B -
Drosophila melanogaster (Fruit fly)
Length = 252
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = -3
Query: 492 VHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGA 313
V + R IA + Q YTQ+ RP G S ++ +D++ P ++TDPSG + ++A G
Sbjct: 106 VEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGR 165
Query: 312 KTVDGNAYLEKKLKRRXDLSTD-DAIQLAISCLSQVLSVDFKSSEIEI 172
+ Y+EK ++ + AI+ + L V S++ E+ +
Sbjct: 166 SSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAV 213
>UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1;
Guillardia theta|Rep: Similar to proteasome A-type
submit - Guillardia theta (Cryptomonas phi)
Length = 233
Score = 53.6 bits (123), Expect = 3e-06
Identities = 34/134 (25%), Positives = 67/134 (50%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
Q+KYG +I L + ++ Q +T ++ RPLG S+ ++ D + GP ++ + SG
Sbjct: 94 QHKYGHQISTASLSKDLSSFLQNFTSSSGFRPLGVSLNILGIDKD-GPELFEINTSGEIN 152
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
+ G + D Y+ + + +L T ++L I+CL+ V K EI I ++
Sbjct: 153 DVNFSSIGKSSKDIKEYI--RARWCSNLETKTLLKLVINCLNYYNLVTSKLVEIVIATIN 210
Query: 159 KDNPKFRVLTETEI 118
PK ++ ++ ++
Sbjct: 211 -TQPKIKIFSKEDL 223
>UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1;
Babesia bovis|Rep: Proteasome alpha 5 subunit, putative
- Babesia bovis
Length = 250
Score = 53.6 bits (123), Expect = 3e-06
Identities = 35/117 (29%), Positives = 56/117 (47%)
Frame = -3
Query: 468 ADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAY 289
+DI + RP G ++++ D + GP + DPSG YKA A G+ +
Sbjct: 124 SDIFDTRKKKTMSRPFGVALLVGGIDID-GPSIWCVDPSGTSIKYKASAIGSAQEGAESV 182
Query: 288 LEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEI 118
L+++ R D+S DA L + L QV+ + IE+ + + +FR TE EI
Sbjct: 183 LQERY--RDDMSFRDAELLVLEVLRQVMKDQMTTKNIEMARIKIHDRQFREYTEDEI 237
>UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative;
n=5; Plasmodium|Rep: Proteosome subunit alpha type 1,
putative - Plasmodium vivax
Length = 269
Score = 53.6 bits (123), Expect = 3e-06
Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 2/146 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
++ + + + L +++AD Q TQ + R G +++ Y E P ++T P+G Y
Sbjct: 96 KFLFDENMNIEKLVKKVADKYQQNTQRSSRRAFGVGLIIAGYFKE--PYIFETKPNGSYF 153
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSV--DFKSSEIEIGV 166
Y A++ GA++ YLEK + D S ++ + L LS + I +
Sbjct: 154 EYIALSFGARSHASKTYLEKNVHLFEDSSLEELTIHCLKALRCSLSSENELTIENTSIAI 213
Query: 165 VSKDNPKFRVLTETEIDRHLTAIAEK 88
V KD P + T ++ + AE+
Sbjct: 214 VGKDKPWQEITTVDLVELLIRVNAEQ 239
>UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1;
Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit -
Trypanosoma brucei
Length = 237
Score = 52.8 bits (121), Expect = 5e-06
Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Frame = -3
Query: 486 ILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKT 307
+L RI + VYT + RP GCS+++ +Y D+ GP Y DPSG Y +A G
Sbjct: 109 LLASRIGEFMHVYTTHYAYRPFGCSVIIASYADD-GPQLYVADPSGAVAGYYGIALGKGK 167
Query: 306 VDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQV--LSVDFKSSEIEIGVVSKDNPKFRVL 133
LEK L+ +A++ + L +V S D K E+E+ V + + V
Sbjct: 168 TVAKTELEK--LDFATLTCSEAVEKLTNILHEVHDKSKD-KIYEVEVAWVCDKSDRTFVH 224
Query: 132 TETEIDRHLT 103
E+ H T
Sbjct: 225 VPKEMVPHPT 234
>UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11;
Eukaryota|Rep: Proteasome subunit alpha type-3 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 52.8 bits (121), Expect = 5e-06
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 1/142 (0%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG IP+ +L +RIA + ++T +RP GCS+ + D+ GP + +PSG Y
Sbjct: 103 YGQPIPIKVLSQRIASYNHMHTLYGSVRPFGCSIAITGI-DQYGPQLFLVEPSGSCVGYF 161
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVL-SVDFKSSEIEIGVVSKD 154
+ G LE+ R +++ +AI+ + V V K E+E+G +S +
Sbjct: 162 GASLGKGKQAAKNELEE--IRFSEMTCREAIKEVSRIIYSVHDEVKDKDFELELGWISTE 219
Query: 153 NPKFRVLTETEIDRHLTAIAEK 88
+ E+ A A++
Sbjct: 220 TDNVHQIVPKELHDEGEAYAKQ 241
>UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia
intestinalis|Rep: GLP_47_22543_21776 - Giardia lamblia
ATCC 50803
Length = 255
Score = 50.8 bits (116), Expect = 2e-05
Identities = 40/143 (27%), Positives = 69/143 (48%), Gaps = 6/143 (4%)
Frame = -3
Query: 516 YKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYD---DEAGPCXYKTDPSGY 346
Y Y + PV L ++A+ +Q TQ RP G S+++ D ++ P Y P+
Sbjct: 94 YVYDTPHPVGPLVAKLAEDAQARTQFWGYRPYGASLLIGGIDTRNNKQTPRLYVLSPNAV 153
Query: 345 YCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE--IEI 172
+ Y+AV+ G + N +L+ + + S + I LA+ L + D + SE + I
Sbjct: 154 FKEYRAVSLGMGSQTINTHLKSHVDEYENASVERLIALALDSLGTGVK-DCRPSEKNLSI 212
Query: 171 GVVSK-DNPKFRVLTETEIDRHL 106
GV+ + R+LT+ EI H+
Sbjct: 213 GVLDRTTGGVLRILTKEEILPHI 235
>UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family
protein; n=5; Oligohymenophorea|Rep: Proteasome A-type
and B-type family protein - Tetrahymena thermophila
SB210
Length = 267
Score = 50.8 bits (116), Expect = 2e-05
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
+Y YGS+ P L +I++ SQ TQ RP G ++IA + + GP ++T PSG +
Sbjct: 113 KYVYGSQHPAQRLVIKISEKSQHKTQTYGKRPYGVGTLIIAQESD-GPKLFQTLPSGDFY 171
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQL-AISCLSQVL--SVDFKSSEIEIG 169
+ + G+++ YLE L+ D + + + L +S L + + ++I
Sbjct: 172 EFYGQSIGSRSQAAKTYLENNLELFKDCNDLNTLILHGLSALKKANQGEEELLPQSVDIA 231
Query: 168 VVSKDNPKFRVLTETEIDRHL 106
V ++ F +L+E + +L
Sbjct: 232 FVGLES-NFTLLSEDRVLSYL 251
>UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2;
Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome
endopeptidase complex - Halorubrum lacusprofundi ATCC
49239
Length = 268
Score = 50.8 bits (116), Expect = 2e-05
Identities = 34/119 (28%), Positives = 57/119 (47%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
+YG + V L + + D Q TQ RP G + +LI D P + DPSG +
Sbjct: 104 RYGEPVGVETLTKFVTDHIQENTQRGGTRPYGAA-LLIGGIDNGEPRLFAADPSGTPNEW 162
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSK 157
KA G D +LE+ +LS D ++LAI+ L+ +F+ +++ + V++
Sbjct: 163 KATVIGGGRSDIQGHLEENWTE--ELSLDAGVELAIAALA-AHDDEFEPTDLAVATVTE 218
>UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus lucimarinus CCE9901
Length = 236
Score = 50.0 bits (114), Expect = 3e-05
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = -3
Query: 456 QVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKK 277
Q+ + + RP G ++L+ ++ G ++T PSG A G ++ YLEK
Sbjct: 117 QISMRKSSGRPCGVGLVLVGSSEQLGCQIFQTCPSGEVHQMSCTAIGGRSQSARTYLEKN 176
Query: 276 LKRRXDLSTDDAIQLAISCL--SQVLSVDFKSSEIEIGVV 163
++ S D+ I +A+ L S V + D S + E+ +V
Sbjct: 177 MEALETASVDEMIMIALRALNESNVDASDLTSDKCEVAIV 216
>UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8;
Eukaryota|Rep: Proteasome subunit alpha type -
Alexandrium fundyense (Dinoflagellate)
Length = 254
Score = 49.2 bits (112), Expect = 6e-05
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
Frame = -3
Query: 519 QYK--YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYD-DEAGPCXYKTDPSG 349
QYK Y EIP +L R+ YT +RP GCS++L D D P + DP+G
Sbjct: 98 QYKNSYNEEIPPELLAERLGLFVHAYTLYWSIRPFGCSVLLGCVDQDTKKPSLFCVDPAG 157
Query: 348 YYCSYKAVAAGAKTVDGNAYLEKKLKRRXD-LSTDDAIQLAISCLSQVLSVDFKSSEIE 175
Y A G +EK L + L+ +A+ L +V K E+E
Sbjct: 158 MVFKYSGTAIGKGKQAAKTEIEKLLANGTESLTCAEALVHVAKILHKVHDEKDKDFELE 216
>UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 306
Score = 49.2 bits (112), Expect = 6e-05
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
Q Y ++ V + ++D +Q TQ+ RP G ++L YD+ +G + PSG
Sbjct: 169 QLVYARDLSVVKAGQLLSDKAQKNTQSYGGRPYGVGLLLAGYDN-SGAHLLEFQPSGNTL 227
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDA-IQLAISCLSQVLSVDFKSSE-IEIGV 166
A GA++ YLE+ ++ ++ DA I+ + L L + S++ + I +
Sbjct: 228 ELYGAAIGARSQGAKTYLERVMEEYLEIEDADALIKHGVEALKHSLKDETLSTKNLSIAI 287
Query: 165 VSKDNP 148
V KD P
Sbjct: 288 VGKDMP 293
>UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1;
Methanocorpusculum labreanum Z|Rep: Proteasome alpha
subunit - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 272
Score = 48.8 bits (111), Expect = 7e-05
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 3/133 (2%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXY---KTDPSGYYC 340
YG + V L +++ D Q YT RP G ++++ + Y +TDPSG
Sbjct: 106 YGEPVDVETLAKKLCDHMQSYTLFGGARPYGTALLIAGAESSPTGTKYHLFETDPSGTLL 165
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVS 160
Y A G E++ K S ++A+ L + L F + +EIG+
Sbjct: 166 EYSATGIGIGRPAVIKLFEQEYKE--TCSAEEAVLLGLKALHTATEGKFDMNTVEIGIAG 223
Query: 159 KDNPKFRVLTETE 121
+ + K E+E
Sbjct: 224 EYSKKHSSKKESE 236
>UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1;
Rattus norvegicus|Rep: Putative uncharacterized protein
- Rattus norvegicus (Rat)
Length = 99
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/78 (37%), Positives = 41/78 (52%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
K G E PV +L +RI D+SQVYTQ+ E+R L C M+ + Y+ + P + C
Sbjct: 25 KCGYEFPVGVLCKRIDDVSQVYTQDNEVRLL-CCMICMGYELKTRPSSVQVGS----CRL 79
Query: 333 KAVAAGAKTVDGNAYLEK 280
A A K ++LEK
Sbjct: 80 YATTAEVKQTQPTSFLEK 97
>UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA,
RIKEN full-length enriched library, clone:C920013M15
product:proteasome (prosome, macropain) subunit, alpha
type 3, full insert sequence; n=13; Euteleostomi|Rep: 2
days neonate thymus thymic cells cDNA, RIKEN full-length
enriched library, clone:C920013M15 product:proteasome
(prosome, macropain) subunit, alpha type 3, full insert
sequence - Mus musculus (Mouse)
Length = 180
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/77 (35%), Positives = 34/77 (44%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+G IP+ L R+A YT + +RP GCS ML +Y G Y DPSG Y
Sbjct: 28 FGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYW 87
Query: 330 AVAAGAKTVDGNAYLEK 280
A G +EK
Sbjct: 88 GCAIGKARQAAKTEIEK 104
>UniRef50_P21242 Cluster: Proteasome component C1; n=18;
Eukaryota|Rep: Proteasome component C1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 288
Score = 45.6 bits (103), Expect = 7e-04
Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y + IP+ R+ Q +T +RP G S + D G Y +PSG Y YK
Sbjct: 103 YKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVDKN-GAHLYMLEPSGSYWGYK 161
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXD-LSTDDAIQLAISCLSQVLSVDFKSSEIEIGV 166
A G A LEK + + LS +A++ A + + D K + E+ +
Sbjct: 162 GAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII-YLAHEDNKEKDFELEI 216
>UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12;
Magnoliophyta|Rep: Proteasome subunit alpha type-3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 249
Score = 45.6 bits (103), Expect = 7e-04
Identities = 26/77 (33%), Positives = 35/77 (45%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG +PV L R+A + T +RP GC ++L YD + GP Y +PSG Y
Sbjct: 103 YGDAVPVKELSERVASYVHLCTLYWWLRPFGCGVILGGYDRD-GPQLYMIEPSGISYRYF 161
Query: 330 AVAAGAKTVDGNAYLEK 280
A G +EK
Sbjct: 162 GAAIGKGKQAAKTEIEK 178
>UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia
intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia
ATCC 50803
Length = 292
Score = 44.8 bits (101), Expect = 0.001
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 10/89 (11%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAG---PCXYKT------- 361
Y +P +L I+ Q+YT E+RP GCS+++ YD A P KT
Sbjct: 122 YSRIVPTGVLANSISGYMQLYTHYGEVRPFGCSLLIAGYDSIASADEPTTLKTKYSLYLL 181
Query: 360 DPSGYYCSYKAVAAGAKTVDGNAYLEKKL 274
PSG + A AAG T LE +
Sbjct: 182 QPSGDITNCFATAAGRHTSQAKVELENHM 210
>UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia
theta|Rep: 26S proteasome SU - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Frame = -3
Query: 519 QYK--YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGY 346
+YK + +P+ + ++DI TQ RPLG S ++ +D+ G +K DPSG
Sbjct: 88 EYKLMFQETVPIEKIVGYLSDIMHKPTQMIYQRPLGVSFIIGGWDEFRGFQLFKIDPSGN 147
Query: 345 YCSYKAVAAGAKTVDGNAYLEKKLKRRXDL 256
+ ++A + G + +E+ + +L
Sbjct: 148 FSGWRATSIGFNNILNQTLIEENYHNKINL 177
>UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1;
Anopheles gambiae str. PEST|Rep: Proteasome subunit
alpha type - Anopheles gambiae str. PEST
Length = 278
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/53 (37%), Positives = 30/53 (56%)
Frame = -3
Query: 498 IPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
IP+ L R++ YT + +RP G S++L ++ +E GP Y DPSG C
Sbjct: 107 IPLKQLNDRLSSYFHAYTLYSAVRPFGVSVILASWSEEKGPEMYMIDPSGVSC 159
>UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 244
Score = 43.2 bits (97), Expect = 0.004
Identities = 27/100 (27%), Positives = 47/100 (47%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+ I IL R +T RP GCS+++ +YD G +++D +GY Y
Sbjct: 97 FSMPISGRILSERTGQYLHAHTLYGAYRPFGCSVIISSYDPIDGLQLHQSDNAGYCLGYY 156
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQ 211
A A G + A+ ++ R DL+ ++A+ I L++
Sbjct: 157 ACAQGQGKQEVMAHFGRRNFR--DLTCEEALPYVILALNK 194
>UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 247
Score = 43.2 bits (97), Expect = 0.004
Identities = 25/65 (38%), Positives = 33/65 (50%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG IPV +L +IA Q +T +RP GCS +LI D+ G + +PSG Y
Sbjct: 103 YGMNIPVKVLAEKIAMYMQNHTLYGSLRPFGCS-LLIGGVDQHGYSLHYIEPSGTTYGYF 161
Query: 330 AVAAG 316
A G
Sbjct: 162 ANGIG 166
>UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;
Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo
sapiens (Human)
Length = 241
Score = 42.3 bits (95), Expect = 0.006
Identities = 28/108 (25%), Positives = 53/108 (49%)
Frame = -3
Query: 438 AEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXD 259
A RP G ++ L DE GP + DPSG + A A G+ + + L++ +
Sbjct: 132 AMSRPFGVAL-LFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK--S 188
Query: 258 LSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 115
++ +AI+ ++ L QV+ ++ IE+ V + F + T+ E++
Sbjct: 189 MTLKEAIKSSLIILKQVMEEKLNATNIELATV-QPGQNFHMFTKEELE 235
>UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1;
Staphylothermus marinus F1|Rep: 20S proteasome, A and B
subunits - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 213
Score = 41.5 bits (93), Expect = 0.011
Identities = 30/110 (27%), Positives = 52/110 (47%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y ++ I R +A I + + ++ PL +++ +D E GP Y DP G K
Sbjct: 83 YELQLGREIRVRGLAKILSLILYSYKLAPLMTEVVVGGFD-EKGPQIYVLDPVGSLIEDK 141
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE 181
VA G+ +EK+ R D+ D+A +LA+S + + + D S +
Sbjct: 142 YVALGSGGPIALGIIEKEY--REDIDVDEAEKLAVSAIREAIERDAVSGD 189
>UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1;
Medicago truncatula|Rep: 20S proteasome, A and B
subunits - Medicago truncatula (Barrel medic)
Length = 336
Score = 40.7 bits (91), Expect = 0.020
Identities = 27/97 (27%), Positives = 49/97 (50%)
Frame = -3
Query: 405 LIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAI 226
LIA D P Y +DP G + A A G ++ + LE++ + DL+ + A +A+
Sbjct: 239 LIAGHDNNRPSLYYSDPFGSFQQCNAKAIGLRSEGADRSLEEQFNQ--DLTLEKAETIAL 296
Query: 225 SCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 115
S L QV+ + ++I V+ P + + T +E++
Sbjct: 297 SILKQVMGEKVTPNNVDIAKVA---PAYHLYTFSELE 330
>UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 200
Score = 40.7 bits (91), Expect = 0.020
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = -3
Query: 435 EMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDL 256
+ RP+ MLI D GP + D G K A G+ + + LE + R DL
Sbjct: 101 QYRPILSVQMLIGGVDSDGPSLFSVDWLGTVTREKYTATGSGSPYAVSLLEHEY--REDL 158
Query: 255 STDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSKDNPKFR 139
S ++A+ LA+ ++ L+ D S E ++I ++K+ + +
Sbjct: 159 SLEEAVNLAVKAVNIALARDPGSGEGVDIATITKEGIRMK 198
>UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative;
n=6; Plasmodium|Rep: 20S proteasome alpha subunit G,
putative - Plasmodium vivax
Length = 253
Score = 39.5 bits (88), Expect = 0.046
Identities = 21/85 (24%), Positives = 40/85 (47%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+ + IP+HIL R++ +T +RP S++L ++D++ Y +P+G Y
Sbjct: 105 FHTNIPLHILANRVSLYLHSFTLYWHLRPFASSIILASFDEKEKGEIYCVEPNGACYKYS 164
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDL 256
V G +EK+ + D+
Sbjct: 165 GVVIGKNKEMFKTEIEKRNYKDVDV 189
>UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar to
human proteasome (prosome, macropain) subunit, alpha
type, 5(PSMA5),; n=1; Macaca fascicularis|Rep: Testis
cDNA, clone: QtsA-18608, similar to human proteasome
(prosome, macropain) subunit, alpha type, 5(PSMA5), -
Macaca fascicularis (Crab eating macaque) (Cynomolgus
monkey)
Length = 117
Score = 39.1 bits (87), Expect = 0.060
Identities = 23/92 (25%), Positives = 46/92 (50%)
Frame = -3
Query: 390 DEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQ 211
DE GP + DPSG + A A G+ + + L++ + ++ +AI+ ++ L Q
Sbjct: 23 DEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK--SMTLKEAIKSSLIILKQ 80
Query: 210 VLSVDFKSSEIEIGVVSKDNPKFRVLTETEID 115
V+ ++ IE+ V + F + T+ E++
Sbjct: 81 VMEEKLNATNIELATV-QPGQNFHMFTKEELE 111
>UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2;
Caenorhabditis|Rep: Proteasome subunit alpha type-3 -
Caenorhabditis elegans
Length = 250
Score = 39.1 bits (87), Expect = 0.060
Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 3/145 (2%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
Y +P+ + +A+ ++T RP G ++++ + G + +PSG YK
Sbjct: 103 YREPMPIQNIANSVAEYIHIHTLGIS-RPFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYK 161
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD-FKSSEIEIGVVSKD 154
A A G A +E KLK +L + ++ A + V + K+ +IE+G V +
Sbjct: 162 AWAVGKHRQAAKAEIE-KLKIE-ELDVNQLVKEAARIIMVVRDENKDKNVQIEMGWVGEQ 219
Query: 153 -NPKF-RVLTETEIDRHLTAIAEKD 85
N K+ V +E AIA+ D
Sbjct: 220 TNGKYEEVPSEVVTAAEEWAIAKLD 244
>UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 38.3 bits (85), Expect = 0.11
Identities = 29/117 (24%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Frame = -3
Query: 519 QYKYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC 340
Q Y + ++L R+A YT + RP G + + +Y+ G + +PSG
Sbjct: 98 QDMYAIPVSANVLSDRVAQYVHAYTMYSGARPFGSATFIASYNTFDGYELFMIEPSGNKY 157
Query: 339 SYKAVAAGAKTVDGNAYLEKKLKRR--XDLSTDDAIQLAISCLSQVLSVDFKSSEIE 175
+Y A G G A + + +RR DL+ +A+ + I+ + + +FK + E
Sbjct: 158 AYHACTHG----KGRAVCKSEFERRNFKDLTCQEAL-VYIAKMLILAHEEFKEKKYE 209
>UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT
ALPHA-4 - Encephalitozoon cuniculi
Length = 224
Score = 37.9 bits (84), Expect = 0.14
Identities = 30/104 (28%), Positives = 44/104 (42%)
Frame = -3
Query: 507 GSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKA 328
G +I + L R +++ Q YT RP G +L E P Y +P G + +
Sbjct: 99 GEDIAIDQLARMLSEYKQRYTVVYHQRPFGVRTVLFGL--EPRPVAYVLEPDGNFSEFFC 156
Query: 327 VAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVD 196
A G K+ YLEK K D ++L I L +V+ D
Sbjct: 157 GAIGQKSQKVCEYLEKGEK-------GDLVRLTILGLMEVVQSD 193
>UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 240
Score = 36.3 bits (80), Expect = 0.43
Identities = 27/113 (23%), Positives = 49/113 (43%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
+G +I V L ++ + RP GC+++ +Y D+A Y +PSG + Y
Sbjct: 103 FGIKITVPQLASEVSQQFHLAHYYQAYRPFGCTVIFASYKDDA---LYAIEPSGAFYGYF 159
Query: 330 AVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEI 172
A G + A L+K +++ +A+ + + FK EIE+
Sbjct: 160 ASCFGKNSNLARAELQK--TEWKNITVREAVPEVARIIKSLHESQFKKWEIEM 210
>UniRef50_Q22MS9 Cluster: Proteasome subunit beta type; n=2;
Oligohymenophorea|Rep: Proteasome subunit beta type -
Tetrahymena thermophila SB210
Length = 227
Score = 35.9 bits (79), Expect = 0.56
Identities = 26/110 (23%), Positives = 47/110 (42%), Gaps = 1/110 (0%)
Frame = -3
Query: 423 LGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDD 244
L ++++ DD GP Y PSG + G+ + +Y++ + DL +
Sbjct: 119 LSAAVIVAGIDDNEGPSIYACQPSGSCIKQQVAIGGSGSGFIFSYVDANFRPNMDL--ES 176
Query: 243 AIQLAISCLSQVLSVDFKSSE-IEIGVVSKDNPKFRVLTETEIDRHLTAI 97
A +L + L+ +S D S I + ++KDN ++ H T I
Sbjct: 177 AKKLVKTALAHAMSRDGSSGGIIRLVNITKDNVTREFFDHKDLPYHFTNI 226
>UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5;
Thermoproteaceae|Rep: Proteasome beta subunit -
Pyrobaculum aerophilum
Length = 202
Score = 35.9 bits (79), Expect = 0.56
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Frame = -3
Query: 393 DDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLS 214
D+E G Y D G K +A G+ + LE + R D++ +DA+ LAI +
Sbjct: 106 DEEEGAVLYMVDWLGTVTKEKYIATGSGSPYAKGALE--VGYREDMTLEDAVDLAIKAVK 163
Query: 213 QVLSVDFKSSE-IEIGVVSKDNPKFRVLT 130
+ D S E I++ V+++ RV T
Sbjct: 164 AAIRNDPGSGEGIDVVVITRKEGFKRVFT 192
>UniRef50_Q2SJX8 Cluster: Outer membrane protein; n=1; Hahella
chejuensis KCTC 2396|Rep: Outer membrane protein -
Hahella chejuensis (strain KCTC 2396)
Length = 587
Score = 35.1 bits (77), Expect = 0.98
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = -3
Query: 234 LAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDR 112
LA+S LS + + F S +++ VV +DN + + L E E+DR
Sbjct: 14 LAVSGLSHAIDIPFFSDKLKYEVVVEDNEELKSLVEDELDR 54
>UniRef50_Q8LIW5 Cluster: P0497A05.6 protein; n=6;
Magnoliophyta|Rep: P0497A05.6 protein - Oryza sativa
subsp. japonica (Rice)
Length = 557
Score = 35.1 bits (77), Expect = 0.98
Identities = 21/37 (56%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = -1
Query: 197 TSSPLRLRLVLSAKIILSF--GC*LKLKSTDISRQSL 93
TS P R RLVL+A ++LSF G L LKST+I R L
Sbjct: 46 TSKPGRKRLVLTASVLLSFLIGLPLLLKSTEIHRSPL 82
>UniRef50_A7Q5W3 Cluster: Chromosome chr14 scaffold_54, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr14 scaffold_54, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 66
Score = 34.7 bits (76), Expect = 1.3
Identities = 20/60 (33%), Positives = 28/60 (46%)
Frame = -3
Query: 318 GAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFR 139
G + +LEK+ D+ DDA+ AI L + S IEIG++ D KFR
Sbjct: 2 GKNVSNAKTFLEKRYT--DDMELDDAVHTAILTLKEGFEGQISSKNIEIGIIGTDR-KFR 58
>UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Aspergillus terreus (strain NIH 2624)
Length = 311
Score = 34.7 bits (76), Expect = 1.3
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEA 382
Y S IPV L R+ Q YT + +RP G + ++ +D EA
Sbjct: 103 YKSPIPVSALSNRLGSYVQAYTLYSSVRPFGITAIIGGWDSEA 145
>UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 204
Score = 34.7 bits (76), Expect = 1.3
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = -3
Query: 390 DEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQ 211
DE G Y DP G VA G+ T + +E K+ D+S D+A+ LA+ +
Sbjct: 110 DEEGSHLYSLDPIGAIIEDDYVALGSGTQLAISIVESNYKK--DMSLDEALSLALKSVYA 167
Query: 210 VLSVDFKSSE-IEIGVVSK 157
+ D S + +++ V+ K
Sbjct: 168 AMKRDAASGDGVDVLVIGK 186
>UniRef50_O23714 Cluster: Proteasome subunit beta type-2-A; n=9;
Magnoliophyta|Rep: Proteasome subunit beta type-2-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 204
Score = 34.3 bits (75), Expect = 1.7
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Frame = -3
Query: 426 PLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYLEKKLKR--RXDLS 253
P ++++ YDDE+G Y D Y + V GA G+ + + R R D+S
Sbjct: 96 PYSVNILMAGYDDESGASLYYID---YIATLHKVDKGAFGY-GSYFSLSTMDRHYRSDMS 151
Query: 252 TDDAIQLAISCLSQVLS-VDFKSSEIEIGVVSKDNPK 145
++AI+L C+ ++ S + I +V KD +
Sbjct: 152 VEEAIELVDKCILEIRSRLVVAPPNFVIKIVDKDGAR 188
>UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE
SUBUNIT C9 - Encephalitozoon cuniculi
Length = 232
Score = 33.9 bits (74), Expect = 2.3
Identities = 20/66 (30%), Positives = 29/66 (43%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
++G E P+ L + + Q +TQ A RP G S + D TDPSG +
Sbjct: 94 RFGVECPLTTLCKFVGQRKQAFTQYAGTRPFGVSFLYAGVID-GKYALMSTDPSGTSNRW 152
Query: 333 KAVAAG 316
K + G
Sbjct: 153 KGMCYG 158
>UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY
SUBUNIT 8 - Encephalitozoon cuniculi
Length = 242
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/104 (27%), Positives = 45/104 (43%)
Frame = -3
Query: 465 DISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYKAVAAGAKTVDGNAYL 286
DI +T+ +R LG + + Y D + + TD SG SYKA G T L
Sbjct: 113 DIFHYFTRGINLRVLGANTLTSVYKDGSFSLLH-TDCSGKTLSYKAACIGKGTRRIKTEL 171
Query: 285 EKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 154
EK + + + + ++ S D K +IEIG+ S +
Sbjct: 172 EKLDIDTMTIEEMVDVGVKVLYMAHDPSKD-KEFDIEIGIASME 214
>UniRef50_Q6FB05 Cluster: Maf-like protein ACIAD1930; n=2;
Acinetobacter|Rep: Maf-like protein ACIAD1930 -
Acinetobacter sp. (strain ADP1)
Length = 198
Score = 33.5 bits (73), Expect = 3.0
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = -3
Query: 222 CLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRHLT 103
C S LS+ +S E ++ KFRVLT+ EI+R++T
Sbjct: 107 CFSTGLSIQHLASGFEHTLIEHYQVKFRVLTDAEIERYVT 146
>UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus tauri
Length = 262
Score = 33.1 bits (72), Expect = 4.0
Identities = 19/65 (29%), Positives = 29/65 (44%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSYK 331
YG IP +L R+A ++T +RP GCS +L D + G Y + +G +
Sbjct: 163 YGDAIPGKVLAERMAHYYHLFTLYWSVRPFGCSTLLGCKDFD-GYHLYLVEQNGECAKMR 221
Query: 330 AVAAG 316
G
Sbjct: 222 GACIG 226
>UniRef50_Q980L4 Cluster: Proteasome subunit; n=4;
Sulfolobaceae|Rep: Proteasome subunit - Sulfolobus
solfataricus
Length = 196
Score = 33.1 bits (72), Expect = 4.0
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Frame = -3
Query: 507 GSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYC--SY 334
G I VH + ++ I Y ++ P S +L DE GP Y DP G +Y
Sbjct: 75 GKPISVHAAAKLLSVILYQY----KVMPF-ISEILFGGVDEKGPQLYVLDPIGSLIEDNY 129
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSE-IEIGVVSK 157
AV +GA+ G LE + ++S D A QL + + D S + I++ ++ K
Sbjct: 130 AAVGSGARIAIG--VLESEYD--PNMSLDVATQLITKAIKASIERDITSGDGIDLAIIDK 185
>UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative;
n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3,
putative - Theileria parva
Length = 267
Score = 32.7 bits (71), Expect = 5.2
Identities = 14/49 (28%), Positives = 25/49 (51%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXY 367
+YG++ PV ++ R+A YT +RP G S++L ++ Y
Sbjct: 110 EYGTKAPVRVIAERVALFVHAYTLYWHVRPFGVSILLAGTNENNSRTTY 158
>UniRef50_Q9U2Y8 Cluster: Putative uncharacterized protein fre-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein fre-1 - Caenorhabditis elegans
Length = 585
Score = 32.3 bits (70), Expect = 6.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Frame = +1
Query: 52 HRQLF*FNLPLILFSDCREMSVDFSFS-QHPKLR-IIFADNTNLNLRGLEVDRQHLRQTR 225
HR LF + P ILF CR D+ FS + P+L + + + G +V QH
Sbjct: 471 HRSLFSAHFPGILFFGCRSEHHDYYFSDEWPELSGVAVIPAFSRDTDGRKVYVQHKMGEN 530
Query: 226 DGKLNRI--IGAEV 261
GK+ R+ +GA+V
Sbjct: 531 AGKIKRMLDLGAQV 544
>UniRef50_A6R382 Cluster: Proteasome component C1; n=3;
Pezizomycotina|Rep: Proteasome component C1 -
Ajellomyces capsulatus NAm1
Length = 426
Score = 32.3 bits (70), Expect = 6.9
Identities = 13/42 (30%), Positives = 22/42 (52%)
Frame = -3
Query: 510 YGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDE 385
Y I H+L R+ +Q YT + +RP G + ++ +D E
Sbjct: 232 YKGPISTHVLASRLGGYAQAYTLYSSVRPFGVTSIIGGWDSE 273
>UniRef50_Q83FM9 Cluster: Riboflavin synthase alpha chain; n=2;
Tropheryma whipplei|Rep: Riboflavin synthase alpha chain
- Tropheryma whipplei (strain Twist) (Whipple's
bacillus)
Length = 237
Score = 31.9 bits (69), Expect = 9.2
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = +2
Query: 44 KRIIDNCFDLIYP*SFSAIAVRCLSISVSVNTRNLGLSLLTTPISISEDLKSTDN 208
++IIDNC + P S S + V+ SI+V G+SL T +++SE L ST N
Sbjct: 131 EQIIDNCLRIKIPDSLSLLVVKSGSIAVD------GVSL--TVVNVSEQLPSTAN 177
>UniRef50_A4AP76 Cluster: Putative uncharacterized protein; n=1;
Flavobacteriales bacterium HTCC2170|Rep: Putative
uncharacterized protein - Flavobacteriales bacterium
HTCC2170
Length = 1157
Score = 31.9 bits (69), Expect = 9.2
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = -3
Query: 282 KKLKRRXDLSTDDAIQLAISCLSQ-VLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDR 112
KKL ++ L ++ ++ IS Q L+VDF+ E+G + KDN + + E+++
Sbjct: 662 KKLSKKQSLLSEQKLKEEISAQEQRELNVDFEELANELGELEKDNQDLKKPIDLEVNK 719
>UniRef50_A2GFB7 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 485
Score = 31.9 bits (69), Expect = 9.2
Identities = 32/121 (26%), Positives = 53/121 (43%)
Frame = -3
Query: 513 KYGSEIPVHILXRRIADISQVYTQNAEMRPLGCSMMLIAYDDEAGPCXYKTDPSGYYCSY 334
KYGS++ + I IS ++ + + L C+ L A +D G Y+CS
Sbjct: 136 KYGSKLKITTDNYTILSISALFCKIIQTN-LNCA--LSAVND--GIIINAISSIEYFCST 190
Query: 333 KAVAAGAKTVDGNAYLEKKLKRRXDLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKD 154
+ K V+ N Y+ K L DL + +Q S +S +L + +S E+ + K
Sbjct: 191 GYIGFFCKYVNSNIYILKYLFSYHDLISKAQVQ---SIISTMLKLLITTSSDEVSPIDKR 247
Query: 153 N 151
N
Sbjct: 248 N 248
>UniRef50_Q2FNX5 Cluster: Sensor protein; n=1; Methanospirillum
hungatei JF-1|Rep: Sensor protein - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 1425
Score = 31.9 bits (69), Expect = 9.2
Identities = 16/51 (31%), Positives = 32/51 (62%)
Frame = -3
Query: 261 DLSTDDAIQLAISCLSQVLSVDFKSSEIEIGVVSKDNPKFRVLTETEIDRH 109
D+ TD++ QL +CL++VL+ + K S +E+ ++ +N VL + + R+
Sbjct: 322 DILTDESKQLFFACLTEVLNSNQKHS-LELVLIDGENAPVTVLVDGSVIRN 371
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 418,003,016
Number of Sequences: 1657284
Number of extensions: 6743390
Number of successful extensions: 18183
Number of sequences better than 10.0: 121
Number of HSP's better than 10.0 without gapping: 17048
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 18095
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 32619212418
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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