Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS303F12f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y17394-1|CAA76761.1| 197|Homo sapiens prefoldin subunit 3 protein. 139 6e-33
BT019604-1|AAV38411.1| 197|Homo sapiens von Hippel-Lindau bindi... 139 6e-33
BC046094-1|AAH46094.1| 197|Homo sapiens von Hippel-Lindau bindi... 139 6e-33
AL356738-8|CAI41469.1| 197|Homo sapiens von Hippel-Lindau bindi... 138 1e-32
U56833-1|AAC50617.1| 166|Homo sapiens VHL binding protein-1 pro... 124 1e-28
U96759-1|AAC23907.1| 160|Homo sapiens von Hippel-Lindau binding... 117 3e-26
CR541932-1|CAG46730.1| 160|Homo sapiens VBP1 protein. 117 3e-26
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 30 4.3
BC040136-1|AAH40136.2| 572|Homo sapiens chromosome 1 open readi... 30 4.3
BC035617-1|AAH35617.1| 642|Homo sapiens NDC80 homolog, kinetoch... 30 4.3
BC017262-1|AAH17262.1| 144|Homo sapiens C1orf2 protein protein. 30 4.3
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 30 4.3
BC008854-1|AAH08854.1| 242|Homo sapiens C1orf2 protein protein. 30 4.3
AL713999-25|CAI95092.1| 572|Homo sapiens chromosome 1 open read... 30 4.3
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 30 4.3
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 30 4.3
AF017790-1|AAB80726.1| 642|Homo sapiens retinoblastoma-associat... 30 4.3
AY396741-1|AAR91619.1| 2850|Homo sapiens hornerin precursor prot... 30 5.7
AL589986-3|CAH70026.1| 2850|Homo sapiens hornerin protein. 30 5.7
Z84488-2|CAI23408.1| 958|Homo sapiens squamous cell carcinoma a... 29 7.5
BC039245-1|AAH39245.1| 958|Homo sapiens dermatan sulfate epimer... 29 7.5
BC031242-1|AAH31242.1| 446|Homo sapiens coiled-coil domain cont... 29 7.5
AJ580807-1|CAE45342.1| 529|Homo sapiens mutated in bladder canc... 29 7.5
AF098066-1|AAF00087.1| 958|Homo sapiens squamous cell carcinoma... 29 7.5
>Y17394-1|CAA76761.1| 197|Homo sapiens prefoldin subunit 3 protein.
Length = 197
Score = 139 bits (336), Expect = 6e-33
Identities = 66/129 (51%), Positives = 96/129 (74%), Gaps = 3/129 (2%)
Frame = +1
Query: 142 EGDGVEPSNPKSYSGIPEAEFVDNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLA 321
+G+ + + + GIPEA FV++VD FMK P N E D VLK LDE+++KYK ME LA
Sbjct: 10 KGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGN-ETADTVLKKLDEQYQKYKFMELNLA 68
Query: 322 TKRRRLRQQIPDLARTIEVIEKLKEQKEE---VETQFLLSDQVFVKANVPPTKSVCLWLG 492
K+RRL+ QIP++ +T+E+++ ++++KE +ET+FLL+D ++ KA+VPPT VCLWLG
Sbjct: 69 QKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLG 128
Query: 493 ANVMLEYSL 519
ANVMLEY +
Sbjct: 129 ANVMLEYDI 137
>BT019604-1|AAV38411.1| 197|Homo sapiens von Hippel-Lindau binding
protein 1 protein.
Length = 197
Score = 139 bits (336), Expect = 6e-33
Identities = 66/129 (51%), Positives = 96/129 (74%), Gaps = 3/129 (2%)
Frame = +1
Query: 142 EGDGVEPSNPKSYSGIPEAEFVDNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLA 321
+G+ + + + GIPEA FV++VD FMK P N E D VLK LDE+++KYK ME LA
Sbjct: 10 KGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGN-ETADTVLKKLDEQYQKYKFMELNLA 68
Query: 322 TKRRRLRQQIPDLARTIEVIEKLKEQKEE---VETQFLLSDQVFVKANVPPTKSVCLWLG 492
K+RRL+ QIP++ +T+E+++ ++++KE +ET+FLL+D ++ KA+VPPT VCLWLG
Sbjct: 69 QKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLG 128
Query: 493 ANVMLEYSL 519
ANVMLEY +
Sbjct: 129 ANVMLEYDI 137
>BC046094-1|AAH46094.1| 197|Homo sapiens von Hippel-Lindau binding
protein 1 protein.
Length = 197
Score = 139 bits (336), Expect = 6e-33
Identities = 66/129 (51%), Positives = 96/129 (74%), Gaps = 3/129 (2%)
Frame = +1
Query: 142 EGDGVEPSNPKSYSGIPEAEFVDNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLA 321
+G+ + + + GIPEA FV++VD FMK P N E D VLK LDE+++KYK ME LA
Sbjct: 10 KGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGN-ETADTVLKKLDEQYQKYKFMELNLA 68
Query: 322 TKRRRLRQQIPDLARTIEVIEKLKEQKEE---VETQFLLSDQVFVKANVPPTKSVCLWLG 492
K+RRL+ QIP++ +T+E+++ ++++KE +ET+FLL+D ++ KA+VPPT VCLWLG
Sbjct: 69 QKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLG 128
Query: 493 ANVMLEYSL 519
ANVMLEY +
Sbjct: 129 ANVMLEYDI 137
>AL356738-8|CAI41469.1| 197|Homo sapiens von Hippel-Lindau binding
protein 1 protein.
Length = 197
Score = 138 bits (333), Expect = 1e-32
Identities = 65/129 (50%), Positives = 96/129 (74%), Gaps = 3/129 (2%)
Frame = +1
Query: 142 EGDGVEPSNPKSYSGIPEAEFVDNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLA 321
+G+ + + + GIPEA FV++VD FMK P N E D VLK LDE+++KYK ME LA
Sbjct: 10 KGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGN-ETADTVLKKLDEQYQKYKFMELNLA 68
Query: 322 TKRRRLRQQIPDLARTIEVIEKLKEQKEE---VETQFLLSDQVFVKANVPPTKSVCLWLG 492
K+RRL+ QIP++ +T+E+++ ++++KE +ET+FLL+D ++ KA+VPPT +CLWLG
Sbjct: 69 QKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLG 128
Query: 493 ANVMLEYSL 519
ANVMLEY +
Sbjct: 129 ANVMLEYDI 137
>U56833-1|AAC50617.1| 166|Homo sapiens VHL binding protein-1
protein.
Length = 166
Score = 124 bits (300), Expect = 1e-28
Identities = 58/107 (54%), Positives = 83/107 (77%), Gaps = 3/107 (2%)
Frame = +1
Query: 208 DNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEK 387
++VD FMK P N E D VLK LDE+++KYK ME LA K+RRL+ QIP++ +T+E+++
Sbjct: 1 EDVDSFMKQPGN-ETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKY 59
Query: 388 LKEQKEE---VETQFLLSDQVFVKANVPPTKSVCLWLGANVMLEYSL 519
++++KE +ET+FLL+D ++ KA+VPPT VCLWLGANVMLEY +
Sbjct: 60 MQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDI 106
>U96759-1|AAC23907.1| 160|Homo sapiens von Hippel-Lindau binding
protein protein.
Length = 160
Score = 117 bits (281), Expect = 3e-26
Identities = 55/101 (54%), Positives = 78/101 (77%), Gaps = 3/101 (2%)
Frame = +1
Query: 226 MKSPINAEGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEKLKEQKE 405
MK P N E D VLK LDE+++KYK ME LA K+RRL+ QIP++ +T+E+++ ++++KE
Sbjct: 1 MKQPGN-ETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKE 59
Query: 406 E---VETQFLLSDQVFVKANVPPTKSVCLWLGANVMLEYSL 519
+ET+FLL+D ++ KA+VPPT VCLWLGANVMLEY +
Sbjct: 60 STNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDI 100
>CR541932-1|CAG46730.1| 160|Homo sapiens VBP1 protein.
Length = 160
Score = 117 bits (281), Expect = 3e-26
Identities = 55/101 (54%), Positives = 78/101 (77%), Gaps = 3/101 (2%)
Frame = +1
Query: 226 MKSPINAEGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEKLKEQKE 405
MK P N E D VLK LDE+++KYK ME LA K+RRL+ QIP++ +T+E+++ ++++KE
Sbjct: 1 MKQPGN-ETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKE 59
Query: 406 E---VETQFLLSDQVFVKANVPPTKSVCLWLGANVMLEYSL 519
+ET+FLL+D ++ KA+VPPT VCLWLGANVMLEY +
Sbjct: 60 STNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDI 100
>BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein.
Length = 634
Score = 30.3 bits (65), Expect = 4.3
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +1
Query: 277 DEKHR--KYKVMEYTLATKRRRLRQQIPDLARTIEVIEKLKEQKEEVETQFLLSDQVFVK 450
+EK+ K K+ +A K+R+ + L R E +E L+ +KEE+ET+ +QV +
Sbjct: 542 EEKYNQAKEKLQRAAIAQKKRKSLHE-NKLKRLQEKVEVLEAKKEELETE----NQVLNR 596
Query: 451 ANVP 462
NVP
Sbjct: 597 QNVP 600
>BC040136-1|AAH40136.2| 572|Homo sapiens chromosome 1 open reading
frame 2 protein.
Length = 572
Score = 30.3 bits (65), Expect = 4.3
Identities = 13/50 (26%), Positives = 27/50 (54%)
Frame = -1
Query: 446 TNT*SLRRNCVSTSSFCSFNFSITSIVRAKSGICCRNRLLLVANVYSITL 297
T T S++R+C S + F + FS+ + + IC + ++ ++S+ L
Sbjct: 59 TTTESIKRSCPSWAGFSNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDL 108
>BC035617-1|AAH35617.1| 642|Homo sapiens NDC80 homolog, kinetochore
complex component (S. cerevisiae) protein.
Length = 642
Score = 30.3 bits (65), Expect = 4.3
Identities = 20/82 (24%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Frame = +1
Query: 193 EAEFVDNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLATKRRR----LRQQIPDL 360
E E ++ ++S +N +G+ + LD R+Y+++ T +RR+ L++ + +
Sbjct: 531 ELESLEKHKHLLESTVN-QGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMV 589
Query: 361 ARTIEVIEK-LKEQKEEVETQF 423
A + +EK L+EQ +V+ ++
Sbjct: 590 ATHVGSVEKHLEEQIAKVDREY 611
>BC017262-1|AAH17262.1| 144|Homo sapiens C1orf2 protein protein.
Length = 144
Score = 30.3 bits (65), Expect = 4.3
Identities = 13/50 (26%), Positives = 27/50 (54%)
Frame = -1
Query: 446 TNT*SLRRNCVSTSSFCSFNFSITSIVRAKSGICCRNRLLLVANVYSITL 297
T T S++R+C S + F + FS+ + + IC + ++ ++S+ L
Sbjct: 59 TTTESIKRSCPSWAGFSNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDL 108
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 30.3 bits (65), Expect = 4.3
Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Frame = +1
Query: 247 EGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEK-LKEQKEEVE 414
E ++ + + L++KHRK +E T++R +++I +L + IE ++K L+EQ + E
Sbjct: 487 ERIEELQEQLEQKHRKMNELE----TEQRLSKERIRELQQQIEDLQKSLQEQGSKSE 539
>BC008854-1|AAH08854.1| 242|Homo sapiens C1orf2 protein protein.
Length = 242
Score = 30.3 bits (65), Expect = 4.3
Identities = 13/50 (26%), Positives = 27/50 (54%)
Frame = -1
Query: 446 TNT*SLRRNCVSTSSFCSFNFSITSIVRAKSGICCRNRLLLVANVYSITL 297
T T S++R+C S + F + FS+ + + IC + ++ ++S+ L
Sbjct: 59 TTTESIKRSCPSWAGFSNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDL 108
>AL713999-25|CAI95092.1| 572|Homo sapiens chromosome 1 open reading
frame 2 protein.
Length = 572
Score = 30.3 bits (65), Expect = 4.3
Identities = 13/50 (26%), Positives = 27/50 (54%)
Frame = -1
Query: 446 TNT*SLRRNCVSTSSFCSFNFSITSIVRAKSGICCRNRLLLVANVYSITL 297
T T S++R+C S + F + FS+ + + IC + ++ ++S+ L
Sbjct: 59 TTTESIKRSCPSWAGFSNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDL 108
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 30.3 bits (65), Expect = 4.3
Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Frame = +1
Query: 247 EGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEK-LKEQKEEVE 414
E ++ + + L++KHRK +E T++R +++I +L + IE ++K L+EQ + E
Sbjct: 487 ERIEELQEQLEQKHRKMNELE----TEQRLSKERIRELQQQIEDLQKSLQEQGSKSE 539
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 30.3 bits (65), Expect = 4.3
Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Frame = +1
Query: 247 EGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEK-LKEQKEEVE 414
E ++ + + L++KHRK +E T++R +++I +L + IE ++K L+EQ + E
Sbjct: 487 ERIEELQEQLEQKHRKMNELE----TEQRLSKERIRELQQQIEDLQKSLQEQGSKSE 539
>AF017790-1|AAB80726.1| 642|Homo sapiens retinoblastoma-associated
protein HEC protein.
Length = 642
Score = 30.3 bits (65), Expect = 4.3
Identities = 20/82 (24%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Frame = +1
Query: 193 EAEFVDNVDEFMKSPINAEGVDVVLKSLDEKHRKYKVMEYTLATKRRR----LRQQIPDL 360
E E ++ ++S +N +G+ + LD R+Y+++ T +RR+ L++ + +
Sbjct: 531 ELESLEKHKHLLESTVN-QGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMV 589
Query: 361 ARTIEVIEK-LKEQKEEVETQF 423
A + +EK L+EQ +V+ ++
Sbjct: 590 ATHVGSVEKHLEEQIAKVDREY 611
>AY396741-1|AAR91619.1| 2850|Homo sapiens hornerin precursor
protein.
Length = 2850
Score = 29.9 bits (64), Expect = 5.7
Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 199 EFVDN-VDEFMKSPINAEGVDVVLKSLDEKH-RKYKVMEYTL 318
E ++N + +K+P + + VD++L+SLD H +K EY L
Sbjct: 35 ELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLL 76
>AL589986-3|CAH70026.1| 2850|Homo sapiens hornerin protein.
Length = 2850
Score = 29.9 bits (64), Expect = 5.7
Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 199 EFVDN-VDEFMKSPINAEGVDVVLKSLDEKH-RKYKVMEYTL 318
E ++N + +K+P + + VD++L+SLD H +K EY L
Sbjct: 35 ELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLL 76
>Z84488-2|CAI23408.1| 958|Homo sapiens squamous cell carcinoma
antigen recognized by T cells 2 protein.
Length = 958
Score = 29.5 bits (63), Expect = 7.5
Identities = 16/58 (27%), Positives = 28/58 (48%)
Frame = +1
Query: 247 EGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEKLKEQKEEVETQ 420
E +D + ++ ++ K + A KR + +PD+ IEV EK QK ++ Q
Sbjct: 788 EAIDRIFAISQQQQQQSKSKKNRRAGKRYKFVDAVPDIFAQIEVNEKKIRQKAQILAQ 845
>BC039245-1|AAH39245.1| 958|Homo sapiens dermatan sulfate epimerase
protein.
Length = 958
Score = 29.5 bits (63), Expect = 7.5
Identities = 16/58 (27%), Positives = 28/58 (48%)
Frame = +1
Query: 247 EGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEKLKEQKEEVETQ 420
E +D + ++ ++ K + A KR + +PD+ IEV EK QK ++ Q
Sbjct: 788 EAIDRIFAISQQQQQQSKSKKNRRAGKRYKFVDAVPDIFAQIEVNEKKIRQKAQILAQ 845
>BC031242-1|AAH31242.1| 446|Homo sapiens coiled-coil domain
containing 112 protein.
Length = 446
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 331 RRLRQQIPDLARTIEVIEKLKEQKEEVE 414
++L+ Q+ D+ T + +EKL+E EE+E
Sbjct: 53 KKLQHQLKDVKPTPDFVEKLREMMEEIE 80
>AJ580807-1|CAE45342.1| 529|Homo sapiens mutated in bladder cancer
1 protein.
Length = 529
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/28 (39%), Positives = 20/28 (71%)
Frame = +1
Query: 331 RRLRQQIPDLARTIEVIEKLKEQKEEVE 414
++L+ Q+ D+ T + +EKL+E EE+E
Sbjct: 136 KKLQHQLKDVKPTPDFVEKLREMMEEIE 163
>AF098066-1|AAF00087.1| 958|Homo sapiens squamous cell carcinoma
antigen recognized by T cell protein.
Length = 958
Score = 29.5 bits (63), Expect = 7.5
Identities = 16/58 (27%), Positives = 28/58 (48%)
Frame = +1
Query: 247 EGVDVVLKSLDEKHRKYKVMEYTLATKRRRLRQQIPDLARTIEVIEKLKEQKEEVETQ 420
E +D + ++ ++ K + A KR + +PD+ IEV EK QK ++ Q
Sbjct: 788 EAIDRIFAISQQQQQQSKSKKNRRAGKRYKFVDAVPDIFAQIEVNEKKIRQKAQILAQ 845
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 61,780,918
Number of Sequences: 237096
Number of extensions: 1099183
Number of successful extensions: 3126
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 3032
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3115
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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