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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ovS303B03f
         (521 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc metal...   260   1e-68
UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc metal...   199   4e-50
UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep: CG9...   198   5e-50
UniRef50_UPI00015B614A Cluster: PREDICTED: similar to neprilysin...   147   2e-34
UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;...   135   5e-31
UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;...   135   7e-31
UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral en...   124   9e-28
UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;...   123   3e-27
UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral en...   117   2e-25
UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin...   113   3e-24
UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7; Endopterygot...   113   3e-24
UniRef50_UPI00015B429F Cluster: PREDICTED: similar to endothelin...   109   3e-23
UniRef50_P78562 Cluster: Phosphate-regulating neutral endopeptid...   108   7e-23
UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin...   107   1e-22
UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella ve...   106   4e-22
UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin...   105   6e-22
UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116; ...   105   8e-22
UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral en...   103   3e-21
UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD257...   102   6e-21
UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella ve...   102   6e-21
UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral en...   101   1e-20
UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole...   101   1e-20
UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral en...    99   3e-20
UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to ENSANGP000...    99   3e-20
UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia cal...    97   2e-19
UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella ve...    96   5e-19
UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:...    95   1e-18
UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella ve...    91   1e-17
UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral en...    85   9e-16
UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -...    84   2e-15
UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome s...    83   3e-15
UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4...    83   4e-15
UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep: ...    82   7e-15
UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella ve...    81   1e-14
UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella ve...    79   6e-14
UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2; ...    76   4e-13
UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (...    76   4e-13
UniRef50_UPI0000F1FC7B Cluster: PREDICTED: similar to endothelin...    75   1e-12
UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=...    74   2e-12
UniRef50_A6L1Y4 Cluster: Putative endothelin-converting enzyme; ...    69   5e-11
UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobac...    69   9e-11
UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydr...    69   9e-11
UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep: Nepr...    66   3e-10
UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria (class...    62   7e-09
UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep: Nepr...    61   1e-08
UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precurso...    59   5e-08
UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella ve...    59   5e-08
UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5; Prot...    57   3e-07
UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella ve...    57   3e-07
UniRef50_A6S9J8 Cluster: Putative uncharacterized protein; n=2; ...    57   3e-07
UniRef50_A1D6I0 Cluster: Peptidase family M13 protein; n=7; Pezi...    57   3e-07
UniRef50_Q8TPB2 Cluster: Endothelin converting enzyme-like prote...    57   3e-07
UniRef50_Q0HFB8 Cluster: Endothelin-converting enzyme 1 precurso...    56   5e-07
UniRef50_A5IAW9 Cluster: Metallopeptidase PepO, peptidase, M13 f...    56   7e-07
UniRef50_Q4PB20 Cluster: Putative uncharacterized protein; n=1; ...    56   7e-07
UniRef50_A3CXD1 Cluster: Endothelin-converting enzyme 1 precurso...    56   7e-07
UniRef50_UPI0000D56B83 Cluster: PREDICTED: similar to Endothelin...    54   2e-06
UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (E...    54   2e-06
UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase...    54   2e-06
UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33; Eu...    54   2e-06
UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3; Bacteri...    54   3e-06
UniRef50_Q9XZ14 Cluster: CG9634-PA; n=2; Sophophora|Rep: CG9634-...    54   3e-06
UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella ve...    52   8e-06
UniRef50_Q1GSD1 Cluster: Endothelin-converting enzyme 1 precurso...    52   1e-05
UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6; Franc...    52   1e-05
UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;...    51   2e-05
UniRef50_O52071 Cluster: Neutral endopeptidase; n=19; Lactobacil...    51   2e-05
UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1; R...    50   3e-05
UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood...    50   4e-05
UniRef50_A0KHJ6 Cluster: Peptidase, M13 family; n=2; Aeromonas|R...    48   1e-04
UniRef50_Q139J8 Cluster: Endothelin-converting enzyme 1 precurso...    48   2e-04
UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel transf...    47   2e-04
UniRef50_A0QP11 Cluster: Metallopeptidase; n=8; Actinomycetales|...    47   3e-04
UniRef50_A4R2H0 Cluster: Putative uncharacterized protein; n=1; ...    46   5e-04
UniRef50_UPI00015B5D2D Cluster: PREDICTED: similar to Endothelin...    45   0.001
UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1; Vib...    45   0.001
UniRef50_A3UFI2 Cluster: Secreted zinc metalloproteinase; n=4; H...    45   0.001
UniRef50_Q6UEA5 Cluster: Zinc metallopeptidase 6; n=5; Ancylosto...    45   0.001
UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep: CG1452...    44   0.002
UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella ve...    44   0.002
UniRef50_Q7NQ35 Cluster: Probable metallopeptidase; n=1; Chromob...    44   0.003
UniRef50_Q6L063 Cluster: Zinc metalloprotease; n=2; Thermoplasma...    44   0.003
UniRef50_Q88SH6 Cluster: Endopeptidase PepO; n=10; Lactobacillal...    43   0.005
UniRef50_Q5FPC6 Cluster: Metalloprotease; n=1; Gluconobacter oxy...    43   0.005
UniRef50_A6ENN0 Cluster: Putative endopeptidase; n=1; unidentifi...    43   0.005
UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to ENSANGP000...    42   0.006
UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel transf...    42   0.006
UniRef50_Q74M04 Cluster: Endopeptidase O; n=2; Lactobacillus|Rep...    42   0.006
UniRef50_Q7VPA2 Cluster: Metallopeptidase; n=2; Pasteurellaceae|...    42   0.011
UniRef50_Q2FS56 Cluster: Endothelin-converting enzyme 1; n=1; Me...    42   0.011
UniRef50_UPI00003C85BA Cluster: hypothetical protein Faci_030001...    41   0.015
UniRef50_A3CP78 Cluster: Metalloendopeptidase, putative; n=1; St...    41   0.015
UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella ve...    41   0.015
UniRef50_A3HSZ7 Cluster: Metalloendopeptidase PepO; n=3; Bactero...    41   0.020
UniRef50_Q22763 Cluster: Putative uncharacterized protein; n=2; ...    41   0.020
UniRef50_UPI0000E48FBC Cluster: PREDICTED: similar to endothelin...    40   0.026
UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella ve...    40   0.026
UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila melanogaste...    38   0.14 
UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1; ...    37   0.24 
UniRef50_UPI00015B5ABD Cluster: PREDICTED: similar to neutral en...    36   0.74 
UniRef50_UPI000023D0A6 Cluster: hypothetical protein FG02748.1; ...    35   0.98 
UniRef50_Q8PIZ8 Cluster: Metallopeptidase; n=7; Xanthomonadaceae...    35   0.98 
UniRef50_Q8EUQ0 Cluster: End peptidase; n=1; Mycoplasma penetran...    35   0.98 
UniRef50_Q7JMI4 Cluster: Putative uncharacterized protein; n=3; ...    35   0.98 
UniRef50_Q9VAS1 Cluster: CG14523-PA; n=3; Sophophora|Rep: CG1452...    35   1.3  
UniRef50_Q25051 Cluster: Zinc metallopeptidase precursor; n=3; H...    35   1.3  
UniRef50_A3VNT9 Cluster: Peptidase M13 family protein; n=1; Parv...    34   1.7  
UniRef50_Q22SS7 Cluster: Putative uncharacterized protein; n=1; ...    34   2.3  
UniRef50_Q7UM68 Cluster: Probable zinc metalloproteinase; n=1; P...    33   3.0  
UniRef50_Q4JY76 Cluster: Putative endopeptidase; n=1; Corynebact...    33   3.0  
UniRef50_Q2IQ33 Cluster: Endothelin-converting enzyme 1 precurso...    33   3.0  
UniRef50_Q9VAS2 Cluster: CG14528-PA; n=2; Drosophila melanogaste...    33   4.0  
UniRef50_UPI00015B6074 Cluster: PREDICTED: similar to Endothelin...    33   5.2  
UniRef50_Q9VCU1 Cluster: CG4721-PA; n=3; Sophophora|Rep: CG4721-...    33   5.2  
UniRef50_Q5KLS5 Cluster: Endothelin-converting enzyme 1, putativ...    33   5.2  
UniRef50_Q1H499 Cluster: Putative uncharacterized protein; n=1; ...    32   6.9  
UniRef50_Q9VTV4 Cluster: CG5626-PA; n=2; Sophophora|Rep: CG5626-...    32   6.9  
UniRef50_Q7QZ72 Cluster: GLP_22_12403_9005; n=2; Giardia intesti...    32   6.9  
UniRef50_Q6G472 Cluster: Hemin degrading protein; n=3; Bartonell...    32   9.2  

>UniRef50_UPI00015B614C Cluster: PREDICTED: similar to zinc
           metalloprotease; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to zinc metalloprotease - Nasonia
           vitripennis
          Length = 819

 Score =  260 bits (637), Expect = 1e-68
 Identities = 121/173 (69%), Positives = 145/173 (83%)
 Frame = +3

Query: 3   DLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           DLDQASLGLSREYL++G  DK+V AYY YMVDIA +LGAD+ +A  ELKESL+FE+KLAN
Sbjct: 302 DLDQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLAN 361

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           ISLP EKRRNAT+LYNPMT+ +L QKFP +PWLEY + LL   ITV  +E+ IV+VP +I
Sbjct: 362 ISLPSEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLLPSSITVTEDEMVIVNVPSFI 421

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           TDLE LLE+TPKR+QANYVMWR A  SVSYL D++R+RQLAY T +SG+TERE
Sbjct: 422 TDLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTERE 474


>UniRef50_UPI00015B5C72 Cluster: PREDICTED: similar to zinc
           metalloprotease; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to zinc metalloprotease - Nasonia
           vitripennis
          Length = 788

 Score =  199 bits (485), Expect = 4e-50
 Identities = 90/171 (52%), Positives = 125/171 (73%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           LDQ SLGLS+E+L  GF DK V+AYYEYMV+ A L GAD  +A +ELKESL FE+KLA I
Sbjct: 207 LDQTSLGLSQEFLRNGFDDKNVKAYYEYMVEFATLFGADGERAKKELKESLDFEIKLAKI 266

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
           SLPLE+RR+A  LY+P +I ++Q K+  +PW +Y+N +L PH +V  +E+ IV+VP ++ 
Sbjct: 267 SLPLEERRDAEMLYHPFSIKQVQSKYTSIPWAKYLNEILKPHTSVAADEVVIVAVPSFLA 326

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTER 518
           D E L++ TPKR+ ANY++WRV+  S S+L D ++  Q  Y   L+GK E+
Sbjct: 327 DFEKLIQTTPKRILANYLLWRVSMDSASFLGDKVQAIQTKYEAVLTGKKEK 377


>UniRef50_Q9XZ01 Cluster: CG9761-PA; n=15; Endopterygota|Rep:
           CG9761-PA - Drosophila melanogaster (Fruit fly)
          Length = 763

 Score =  198 bits (484), Expect = 5e-50
 Identities = 97/173 (56%), Positives = 127/173 (73%)
 Frame = +3

Query: 3   DLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           DLDQ+SL LSREYL +GF++ LV AYY+YMVDIA+L GA++  A  EL  SL+FEM LAN
Sbjct: 246 DLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALAN 305

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           IS P EKRRN++ LYN  T A+LQ  +P V W++Y+N LL   + V  +E+  +SVP + 
Sbjct: 306 ISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFF 365

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
            DL  LL KTPKRV ANY+ WR+ G SV +L+++ R+RQL Y TALSG+ E+E
Sbjct: 366 EDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQE 418


>UniRef50_UPI00015B614A Cluster: PREDICTED: similar to
           neprilysin-like protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neprilysin-like protein - Nasonia
           vitripennis
          Length = 979

 Score =  147 bits (356), Expect = 2e-34
 Identities = 73/170 (42%), Positives = 112/170 (65%), Gaps = 1/170 (0%)
 Frame = +3

Query: 15  ASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLP 194
           A+  +S  YL  G S K+  AYY+YMVDIA++LGADK  AT+++++ L FE++L NI   
Sbjct: 219 ATTRVSPTYLLDGPSGKIPNAYYDYMVDIAVMLGADKDFATKDMQKCLDFEVELFNIQSS 278

Query: 195 LEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLL-APHITVDVNELTIVSVPKYITDL 371
           LE   N T+ +NP+TI  L +K+P +PWLE I+ +L   +++VD NE+ IV+   + + +
Sbjct: 279 LEILMNITATHNPITIIGLSEKYPSIPWLELISEVLNLSNVSVDENEVVIVNDLNFFSKI 338

Query: 372 EALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           E L+ +TPKRV ANY++W+V   S+ YL D    R+L +   + G  ER+
Sbjct: 339 EKLIARTPKRVIANYLIWQVVYDSIDYLPDAFLDRKLMFSRVVRGVKERK 388


>UniRef50_UPI0000D56384 Cluster: PREDICTED: similar to CG9761-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 737

 Score =  135 bits (327), Expect = 5e-31
 Identities = 62/156 (39%), Positives = 105/156 (67%)
 Frame = +3

Query: 48  RGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLY 227
           +GF+D  V+A YEY+V++A+L GAD+T A  E++E ++F+++LA + +P E+R+N +  Y
Sbjct: 236 KGFNDTAVKAGYEYLVELAVLFGADRTAARAEMREVVEFQIELAKMIIPYEERKNVSLSY 295

Query: 228 NPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQ 407
           NP+TI ELQ+ F  +PWL+ IN  L+P I +  + +  V+VP ++  LE  L    KRV 
Sbjct: 296 NPVTIRELQRNFTTIPWLKLINNYLSP-IMLTSDTVVNVAVPTFLERLENFLPTVKKRVL 354

Query: 408 ANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
           ANY+  R+  AS ++L ++ R++ L ++  + G+ E
Sbjct: 355 ANYMFTRLVVASTTHLPEEFRKKDLDFVRTVYGQKE 390


>UniRef50_UPI0000D56387 Cluster: PREDICTED: similar to CG9761-PA;
           n=2; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 731

 Score =  135 bits (326), Expect = 7e-31
 Identities = 60/172 (34%), Positives = 109/172 (63%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           LDQ  +    + + RG+++ +V+AY+ YM  IA+  GA++ +A   + + +  ++ +  I
Sbjct: 215 LDQPFIVSFDKLMRRGYNESIVRAYHVYMSKIAMAFGAEEERAYRHMLDVINLDIAITRI 274

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
           ++P EKRRN++   N  +I +L+++FP VPWL+YIN +L P   +  ++   V++P+Y  
Sbjct: 275 TVPSEKRRNSSLEDNRYSIKDLEKEFPYVPWLQYINTMLDPVKIMTYDDNITVTLPQYFK 334

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           +L+ ++  TPK+  ANY+ W+     + YL++DLR  QL +   +SG+TERE
Sbjct: 335 ELKNIITSTPKQTMANYIFWKGIKGLIQYLSNDLRALQLDFFKVVSGRTERE 386


>UniRef50_UPI00015B642B Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 725

 Score =  124 bits (300), Expect = 9e-28
 Identities = 60/154 (38%), Positives = 94/154 (61%)
 Frame = +3

Query: 27  LSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKR 206
           +  E L RGF +++VQAYY YMVD+A++LGAD+ +AT +L+++L  E  +   S      
Sbjct: 213 IKSEILKRGFMNEVVQAYYNYMVDVAVILGADRVRATRDLRKALDLERDITFAS----SF 268

Query: 207 RNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLE 386
            + TS  N   + +L++    VPWLEYIN + +P ++ ++ E   V    Y+  L+  L 
Sbjct: 269 PSITSAINLRRLEDLEKDAAFVPWLEYINAITSPVVSFEIFEAVNVPDLGYLKSLDYFLR 328

Query: 387 KTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAY 488
           KTPK+V ANY++W++   S  YLTD++R R   Y
Sbjct: 329 KTPKKVMANYMIWKMIAESAIYLTDEIRDRAFEY 362


>UniRef50_UPI0000D5569C Cluster: PREDICTED: similar to CG9761-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9761-PA - Tribolium castaneum
          Length = 740

 Score =  123 bits (296), Expect = 3e-27
 Identities = 61/168 (36%), Positives = 101/168 (60%), Gaps = 1/168 (0%)
 Frame = +3

Query: 9   DQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANIS 188
           D+  L +   Y     ++++   Y EYMVD+A+L+GA++ +A EE ++ L+F +KLA IS
Sbjct: 218 DKYVLNIKSPYYQSQINNEIKNWYLEYMVDVAVLMGAERERAREEQRQVLEFLLKLAKIS 277

Query: 189 LPLEKR-RNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
              EK   N T LYNP++++ELQ +F ++ W EYIN +L P   +  +++  VS P Y+ 
Sbjct: 278 ---EKNGANQTQLYNPLSLSELQYEFSEIRWKEYINNILQPVTEITYDDIISVSEPLYLK 334

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 509
            L  LL+ T +R+ AN++ W +    V+YL   +  +   Y+T  +GK
Sbjct: 335 TLLRLLKHTDERIIANFMCWHILQDLVTYLPQKILSKAYDYVTKATGK 382


>UniRef50_UPI00015B6148 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 727

 Score =  117 bits (281), Expect = 2e-25
 Identities = 56/152 (36%), Positives = 92/152 (60%), Gaps = 1/152 (0%)
 Frame = +3

Query: 63  KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 242
           KL +AY+ ++V+IA  LG DK +  EE+K+   FE+ L  I    E  +  +     MT+
Sbjct: 230 KLKKAYFNFIVNIAATLGVDKDQIYEEVKDIFDFEINLYKIET--EDSQKQSQEQTKMTL 287

Query: 243 AELQQKFPKVPWLEYINRLLAPH-ITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYV 419
            EL + +P +PWLE +N +  P  + +D  E+ I+   +YIT LE L+E TPKRV ANY+
Sbjct: 288 KELSKNYPSIPWLELLNHVFNPSGVIIDETEVVIIEDLEYITKLEKLIEITPKRVIANYL 347

Query: 420 MWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
           +W+V  +S+ Y+  + R  +  Y+  ++G+T+
Sbjct: 348 VWKVVQSSLGYMPSEFRVLEADYLNQVNGRTQ 379


>UniRef50_UPI0000E48FBB Cluster: PREDICTED: similar to neprilysin;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neprilysin - Strongylocentrotus purpuratus
          Length = 763

 Score =  113 bits (271), Expect = 3e-24
 Identities = 58/155 (37%), Positives = 100/155 (64%), Gaps = 4/155 (2%)
 Frame = +3

Query: 6   LDQASLGLS-REY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 179
           +DQ+SLG+S REY LN     K+  AY + MV IA LLGAD   A  ++ ++  FE++LA
Sbjct: 247 IDQSSLGISSREYFLNTEKYQKVQDAYLKLMVTIATLLGADAQVAQSDMWDAFNFEIELA 306

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDV--NELTIVSVP 353
           N+++P   RR++ +LYNP T+  L Q +P++ W  + + ++ P+++  +  +E      P
Sbjct: 307 NLTVPPSDRRDSDALYNPTTLTGLMQDYPQMDWTRFFD-IVLPNVSKPLADDEFINNKEP 365

Query: 354 KYITDLEALLEKTPKRVQANYVMWRVAGASVSYLT 458
           +++TD+ AL+++TP R+ ANY++WR+    V  L+
Sbjct: 366 EFVTDVLALVQRTPLRILANYMIWRITKLRVMNLS 400


>UniRef50_Q9W436 Cluster: CG5905-PA, isoform A; n=7;
           Endopterygota|Rep: CG5905-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 849

 Score =  113 bits (271), Expect = 3e-24
 Identities = 59/173 (34%), Positives = 100/173 (57%), Gaps = 2/173 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           +DQ    L SR+Y  +  S    +AY+ YM  +A+LLGAD   A  EL++ + FE +L N
Sbjct: 334 MDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVN 393

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           +SLP   R + + +Y  M + ELQ+  P+V W EY+   L P I +  +E  +     Y+
Sbjct: 394 VSLPEADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYL 453

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTER 518
           T++  +L  T +RV  NY++WR+  + +S++ D+ +R ++ +   L G ++ER
Sbjct: 454 TEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSER 506


>UniRef50_UPI00015B429F Cluster: PREDICTED: similar to
           endothelin-converting enzyme; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           endothelin-converting enzyme - Nasonia vitripennis
          Length = 1000

 Score =  109 bits (263), Expect = 3e-23
 Identities = 60/168 (35%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
 Frame = +3

Query: 9   DQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           DQ +LGL +++Y  +  +   + AY  Y++ IA LLGA    A+ + +E +QFE++LANI
Sbjct: 487 DQTTLGLPTKDYFLQPANAIYLMAYKNYLITIASLLGASVKSASIQAEELIQFEIRLANI 546

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
           ++   +R N + LY  MT+ EL+Q  P + W  Y++ +LA    VD++E  +V   KY  
Sbjct: 547 TISSNERHNISDLYKRMTLRELRQMIPLIDWHRYLSIVLARR--VDLSEPVVVFATKYFQ 604

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 509
           DL  LL  T  R  ANY++WR     V+ L D  +  +  +   L G+
Sbjct: 605 DLVQLLSHTSPRTVANYLLWRFVRHRVNNLDDRFQEAKQTFYYILFGR 652


>UniRef50_P78562 Cluster: Phosphate-regulating neutral
           endopeptidase; n=33; Euteleostomi|Rep:
           Phosphate-regulating neutral endopeptidase - Homo
           sapiens (Human)
          Length = 749

 Score =  108 bits (260), Expect = 7e-23
 Identities = 62/177 (35%), Positives = 102/177 (57%), Gaps = 8/177 (4%)
 Frame = +3

Query: 6   LDQASLGLS--REYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           LDQA+L L+   +YL+     K  + A Y++MVD A+LLGA+ ++A  ++K  L+ E+K+
Sbjct: 222 LDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKI 281

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRL----LAPHI-TVDVNELTI 341
           A I +P E  R + ++YN M I+EL    P+  WL YI ++    L PH+  +  +E  +
Sbjct: 282 AEIMIPHE-NRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVV 340

Query: 342 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKT 512
           V VP+Y  DL  +L    K+  ANY++WR+  + +  L+   + R L +   + G T
Sbjct: 341 VRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTT 397


>UniRef50_UPI0000E492B7 Cluster: PREDICTED: similar to neprilysin;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to neprilysin - Strongylocentrotus purpuratus
          Length = 665

 Score =  107 bits (258), Expect = 1e-22
 Identities = 63/175 (36%), Positives = 92/175 (52%), Gaps = 3/175 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGAD--KTKATEELKESLQFEMKL 176
           LDQ  LG+ SREY  R  SDKLVQAY  YM  I   L  D   T   EE+  +  FE ++
Sbjct: 146 LDQPELGMKSREYFLRDKSDKLVQAYITYMNSIVKELRPDLNDTYIAEEMNAAYDFEREI 205

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           AN SL   +RR+   +YN  T+  L    P + W  Y+N +      ++ +      + +
Sbjct: 206 ANASLAKAERRDLLKIYNKTTLQNLGAMAPGINWFRYLNLVFNDDSLLETDLFNTFDL-Q 264

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           Y+ ++  ++ +TPKRV AN++MWRV   S+SYL   L   +L Y   + G+   E
Sbjct: 265 YLINIADIVTRTPKRVMANFLMWRVTMKSMSYLCPRLLHHRLEYRKVVDGERADE 319


>UniRef50_A7S4D9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 710

 Score =  106 bits (254), Expect = 4e-22
 Identities = 60/162 (37%), Positives = 93/162 (57%), Gaps = 3/162 (1%)
 Frame = +3

Query: 6   LDQASLGLS-REYLNRGFSDKLVQAYYEYMVDIAILL-GADKTKATEELKESL-QFEMKL 176
           + QA + LS REY  R  SDK+V+ Y E+MV IA LL GA     T  L + + QFE KL
Sbjct: 196 IQQAGITLSDREYYTRNESDKVVKKYKEFMVKIATLLNGATADSTTGILMDEIFQFEKKL 255

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           A I  P E+ R++  +Y+ MT+ +LQQ  P +PW++Y+N L +  +  D  E  +V  P 
Sbjct: 256 AEIYEPKERLRHSDKIYHKMTVEDLQQLAPAIPWMDYMNNLFSTPVGHD--EPVVVYTPT 313

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQL 482
           ++  +  L+ +T +R+ ANY++W +     + L+   R   L
Sbjct: 314 FLKSMSDLVIRTDRRILANYMVWHLIKPLTTELSKPYREAAL 355


>UniRef50_UPI0000DB773A Cluster: PREDICTED: similar to Neprilysin 4
           CG4058-PA, isoform A; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Neprilysin 4 CG4058-PA, isoform A
           - Apis mellifera
          Length = 826

 Score =  105 bits (252), Expect = 6e-22
 Identities = 60/170 (35%), Positives = 95/170 (55%), Gaps = 1/170 (0%)
 Frame = +3

Query: 9   DQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           DQ SLGL +R+Y  +  +   ++AY  Y++ I+ LLGA    AT +  E ++FE KLA I
Sbjct: 313 DQTSLGLPTRDYFLQPSNMIYLKAYKNYLIKISTLLGASLQNATMDADELIEFETKLAKI 372

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
           +   ++RRN + LY  M+I EL+   P++ W  Y+  +LA     +++E  +V   +YI 
Sbjct: 373 TSSPDERRNLSELYQRMSIGELRTLIPQINWHRYLTIVLAR--PTNISEPVVVYAMQYIQ 430

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
           DL  LL KT  R  ANY++WR     V+ L D  +  +  +   L G+ +
Sbjct: 431 DLVNLLSKTSPRTIANYLLWRFVRHRVNNLDDRFQEAKQKFYYILFGREQ 480


>UniRef50_O60344 Cluster: Endothelin-converting enzyme 2; n=116;
           Euteleostomi|Rep: Endothelin-converting enzyme 2 - Homo
           sapiens (Human)
          Length = 787

 Score =  105 bits (251), Expect = 8e-22
 Identities = 55/169 (32%), Positives = 101/169 (59%), Gaps = 2/169 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 179
           +DQ+ L L SR+Y LNR  ++K++ AY +YM ++ +LLG   T   E++++ L+ E++LA
Sbjct: 273 VDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLA 332

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
           NI++P ++RR+   +Y+ M+I+ELQ   P + WLE+++ LL+P + +  +E  +V    Y
Sbjct: 333 NITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP-LELSDSEPVVVYGMDY 391

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
           +  +  L+ +T   +  NY++W +   + S L       Q   +  L G
Sbjct: 392 LQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYG 440


>UniRef50_UPI00015B6147 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 721

 Score =  103 bits (246), Expect = 3e-21
 Identities = 52/153 (33%), Positives = 84/153 (54%)
 Frame = +3

Query: 15  ASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLP 194
           A+L     +L  GF+ + +Q +Y +MV++A+ LGA + +A  EL + L FEM+LAN +  
Sbjct: 228 ATLEFHPIFLKLGFNHQSIQIFYNFMVNVAVYLGAHRVRAAAELADVLTFEMQLANAAST 287

Query: 195 LEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLE 374
                      N  TI  L+   P V WL+Y+N L+ P   +++N++  V  P Y+  L 
Sbjct: 288 TYSEPT-----NNFTIQNLETHIPIVSWLKYLNGLIEPAAHLEINDIVHVENPNYLNQLA 342

Query: 375 ALLEKTPKRVQANYVMWRVAGASVSYLTDDLRR 473
            L+  T KR  ANY++WR+   S+ +L   + R
Sbjct: 343 FLMTTTRKRTIANYIIWRITYESIPHLNTPIPR 375


>UniRef50_Q8T062 Cluster: LD25753p; n=3; Endopterygota|Rep: LD25753p -
            Drosophila melanogaster (Fruit fly)
          Length = 1040

 Score =  102 bits (244), Expect = 6e-21
 Identities = 58/170 (34%), Positives = 92/170 (54%), Gaps = 1/170 (0%)
 Frame = +3

Query: 9    DQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
            DQ  LGL +REY  +  + K +QAY  YM ++   +GA K  A     E + FE +LA I
Sbjct: 525  DQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGI 584

Query: 186  SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
            + P E+R N T LY  MT+ +LQ   P++ W  Y+  L    + +   E+ I +V +Y++
Sbjct: 585  TAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREV-LGTEEVVIYAV-EYMS 642

Query: 366  DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
             L  LL++T  R  +NY+MWR     ++ + D     + ++  AL G+ E
Sbjct: 643  KLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREE 692


>UniRef50_A7S3J6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 690

 Score =  102 bits (244), Expect = 6e-21
 Identities = 57/162 (35%), Positives = 94/162 (58%)
 Frame = +3

Query: 3   DLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           ++DQA   LSRE      S K+++AY +Y++D+  LL   K    +  +E +  E KLAN
Sbjct: 165 EIDQAGPSLSREVYTD--SPKIIKAYKKYIIDVGTLLRG-KEAMEKYAQEIIDLETKLAN 221

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           IS+P   +    + +N MTI +L ++ P   WL+++N++ AP    D  ++ + ++P Y+
Sbjct: 222 ISVPDADKTE--TWFNRMTIKDLMKEAPGYDWLDHLNKMFAPEKIKDSEQIIVPALP-YL 278

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAY 488
             +  L+E TPKRV +NYV+W V    VS+L+   R  +L Y
Sbjct: 279 KKMIKLIENTPKRVLSNYVVWNVIQDEVSFLSKPYRDVRLRY 320


>UniRef50_UPI00015B642C Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 517

 Score =  101 bits (242), Expect = 1e-20
 Identities = 54/144 (37%), Positives = 79/144 (54%)
 Frame = +3

Query: 42  LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATS 221
           L  GF  + VQ YY Y + +A LLGADK +A  EL+E + FE +LA              
Sbjct: 164 LAHGFGHETVQLYYNYTMKVAQLLGADKQRAALELREVIYFERRLALFGQ---------- 213

Query: 222 LYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKR 401
            +   TI +L++  P++PWLEY+N + AP   ++  E   V  P Y+ +L   L +  KR
Sbjct: 214 -FVVNTIKDLEKTIPQIPWLEYLNNITAPFAELESTEEIKVEKPYYLINLYTALFRAKKR 272

Query: 402 VQANYVMWRVAGASVSYLTDDLRR 473
             ANY++WRV   S  YL+ D+R+
Sbjct: 273 TVANYLIWRVIAESAPYLSSDIRK 296


>UniRef50_Q4T614 Cluster: Chromosome undetermined SCAF8999, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF8999, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 851

 Score =  101 bits (242), Expect = 1e-20
 Identities = 55/174 (31%), Positives = 96/174 (55%), Gaps = 2/174 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 179
           +DQ+SLGL SR+Y LNR   +K + AY  ++V++ +LLG     +   +   + FE  LA
Sbjct: 277 IDQSSLGLPSRDYYLNRTAHEKYLSAYQTFLVELGVLLGGSAEASRTMMGAVVDFETALA 336

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
           NIS+P EKRR+   +Y+ M   +L    P V W+ Y+  + AP + ++ +E  +V   +Y
Sbjct: 337 NISVPQEKRRDEELIYHKMEAKDLADLVPVVDWMPYLTAVFAP-VALNESEPVVVYAREY 395

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           + D+  L+ +T K +  NY++ +V    VS L    +  +  ++  + G  + E
Sbjct: 396 LRDVSELINRTDKSLLNNYMIMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKLE 449


>UniRef50_UPI00015B56F7 Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 651

 Score =   99 bits (238), Expect = 3e-20
 Identities = 59/159 (37%), Positives = 86/159 (54%), Gaps = 4/159 (2%)
 Frame = +3

Query: 42  LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATS 221
           L +G    LV  YY YM++IA  LGA+  +A  ELKESL FE+KLA       K+  +  
Sbjct: 174 LRKGNRSSLVVHYYHYMIEIATFLGANTNRAAAELKESLDFEIKLAQAMTTNNKKFRSIK 233

Query: 222 LYNPMTIAELQQKFPKVPWLEYINRLLAP--HITVDVNELTIVSVPKYITDLEALLEKTP 395
           +    +  +L Q  PKVPW EY+N L  P  HI    N L +  +  Y+  +   L  TP
Sbjct: 234 I---NSTDQLSQIMPKVPWDEYVNCLTEPTIHINKTDNVLRVHKI-NYMFKIRQFLNSTP 289

Query: 396 KRVQANYVMWRVAGASVSYLTDDLRR--RQLAYITALSG 506
           KRV ANY++WRV   ++ +L   + +  R+   ++A +G
Sbjct: 290 KRVLANYMIWRVIADTIPHLPHRINKIERRFRRLSANNG 328


>UniRef50_UPI0000E49A83 Cluster: PREDICTED: similar to
           ENSANGP00000003181; n=3; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000003181
           - Strongylocentrotus purpuratus
          Length = 956

 Score =   99 bits (238), Expect = 3e-20
 Identities = 56/174 (32%), Positives = 100/174 (57%), Gaps = 4/174 (2%)
 Frame = +3

Query: 9   DQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILL--GADKTKATEELKESLQFEMKLA 179
           DQ  LGL +R+Y  R  S K ++AY +YM+D+A+ +   +D+ + T +++E L FE K+A
Sbjct: 252 DQPILGLENRDYFLRNESIKGLEAYQKYMIDMALYVRGDSDREEVTRQMQEVLNFEKKMA 311

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
           NIS+    +R A  +   +++  L+++ P + W  Y  +L+    +VD +   +V  P+Y
Sbjct: 312 NISMTQLAKRRAQIMNQKVSVTYLKRRIPAINWTRYF-QLVMNTSSVDHSMELVVYSPQY 370

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG-KTER 518
           +  L  +L +TP R  ANYV+WR    ++  +  + R  +  ++  +SG K ER
Sbjct: 371 LLGLNQMLLETPNRTIANYVVWRAVTHTMDMMNTEARSIRQTFLKVVSGEKKER 424


>UniRef50_Q9UA44 Cluster: Neutral endopeptidase; n=1; Aplysia
           californica|Rep: Neutral endopeptidase - Aplysia
           californica (California sea hare)
          Length = 787

 Score = 97.1 bits (231), Expect = 2e-19
 Identities = 58/174 (33%), Positives = 98/174 (56%), Gaps = 7/174 (4%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLG-ADKTKATEELKESLQFEMKLA 179
           +DQ + GL  + Y     +D  ++AY  Y+  +A  LG AD   A +++ + + FEM++A
Sbjct: 266 IDQPAFGLPGQRYYRVPRNDTYIKAYETYLYRVAEALGFADPATAEKDVADVVDFEMQIA 325

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLL-APHITVDV--NELTIV 344
            IS+    RRNA +++NPMT+AEL Q F  P++ +   I  ++ AP + V V  +E+ + 
Sbjct: 326 QISVRPAIRRNANAVFNPMTLAELDQDFSSPELNFSRLITTVMSAPEVAVSVGDDEIIMN 385

Query: 345 SVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
             P Y  +L  LL  TPK+  ANY++WR+  + +  LT   +  +  +  A+ G
Sbjct: 386 RSPPYFRNLTDLLRNTPKKTIANYIIWRITISYLGTLTQVFKDIRFEFTKAIYG 439


>UniRef50_A7SSB1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 714

 Score = 95.9 bits (228), Expect = 5e-19
 Identities = 49/173 (28%), Positives = 88/173 (50%), Gaps = 1/173 (0%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGA-DKTKATEELKESLQFEMKLAN 182
           LDQA +G+ R Y     + + + AY EYM  + +LLG  D+T   ++++E L+ E++LA 
Sbjct: 258 LDQAGIGIERSYYLLNETSEELTAYLEYMTRVGVLLGGKDETTVRDKMREVLRLEIQLAQ 317

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           I +P + R     LY  +T+ EL    PK+PW+++ +   +    +  +E  +V   +Y+
Sbjct: 318 IFIPPDNRSQIDQLYTKITVKELISLCPKIPWMDFFSSAFSGVAVIKESESVVVMATEYL 377

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
             L A++    + V  +Y++W V       L+   R    A    L G ++ E
Sbjct: 378 RALSAVISGANQTVLNDYMVWHVVEHFAPSLSSPFRDAHQALRQVLDGASKAE 430


>UniRef50_Q7PQR4 Cluster: ENSANGP00000003181; n=2; Culicidae|Rep:
           ENSANGP00000003181 - Anopheles gambiae str. PEST
          Length = 932

 Score = 94.7 bits (225), Expect = 1e-18
 Identities = 49/168 (29%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
 Frame = +3

Query: 9   DQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           DQ SLGL +R+Y  +  + K ++AY ++M+++  LL      A +   E ++FE +LANI
Sbjct: 415 DQTSLGLPTRDYYLQPGNRKYLEAYRQFMLEVIGLLDVPADTARQATDEMIEFETQLANI 474

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
           +   E+R N ++LY  + + +LQ++ P++ W  Y+   +     V+ +   ++    Y+ 
Sbjct: 475 TSTPEERNNVSTLYRKLMLDQLQEEVPQINWTHYLT--IVTERPVNGSSFVVMFAMSYMR 532

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 509
           DL  L+++T  R+ ANY++WR     ++ L D     +  +  AL G+
Sbjct: 533 DLVELIDQTEPRIVANYLLWRFVRHRINNLDDRFLGAKQRFSNALFGR 580


>UniRef50_A7RFZ0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 676

 Score = 91.1 bits (216), Expect = 1e-17
 Identities = 52/173 (30%), Positives = 97/173 (56%), Gaps = 1/173 (0%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           +DQ+ L L RE   +    ++V  Y EYM  +A LLG  K  AT+E+++ + FE KLANI
Sbjct: 167 VDQSGLSLQREIYFK--HPEMVDTYVEYMAKVATLLGI-KGNATKEMRKIVDFETKLANI 223

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLL-APHITVDVNELTIVSVPKYI 362
           +   E +  A  +Y  + +  L +  P  PWL+++  +    H+T D  ++ + +   Y+
Sbjct: 224 TTSAEDK--ADGIYRRIKLHHLIKLVPGFPWLKHMQAIFRGAHVT-DA-DVVLATPSTYL 279

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           + +  ++++TPK + +NYV+W++    +S L+   R+ +  +   +SG  E+E
Sbjct: 280 SKMNDIIKETPKELLSNYVVWQMIRDKISLLSKPFRKARAVFNHKISGVKEQE 332


>UniRef50_UPI00015B642D Cluster: PREDICTED: similar to neutral
           endopeptidase 24.11; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to neutral endopeptidase 24.11 -
           Nasonia vitripennis
          Length = 604

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 52/159 (32%), Positives = 84/159 (52%), Gaps = 2/159 (1%)
 Frame = +3

Query: 3   DLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           ++ + +  L  E L  G+S   +Q+Y++YM D+A LLGAD   A  E+ +++ FE KLA 
Sbjct: 155 EIVEGTTALEPEILTSGWSHPRLQSYHKYMFDVATLLGADAQIADWEVYKTIDFEAKLAY 214

Query: 183 ISLPLEKRRNATSLYNPM--TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
                       SL N    +IA++    P++PWL+ IN L +P     + +   V    
Sbjct: 215 YV--------DDSLVNEFVGSIADVAFNVPQIPWLDLINNLTSPVANFTMTDEIRVFNQV 266

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRR 473
           Y+ DL  L+    KR   NY++WRV   S  Y+++D+R+
Sbjct: 267 YLNDL-PLISNISKRTVVNYLIWRVIDDSAPYISNDIRQ 304


>UniRef50_Q8SWS1 Cluster: RE48040p; n=9; Neoptera|Rep: RE48040p -
           Drosophila melanogaster (Fruit fly)
          Length = 786

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 51/176 (28%), Positives = 91/176 (51%), Gaps = 9/176 (5%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSD--KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           +DQ  L L + +Y N    +  K++  Y EYM  + +LLGA+++ A  ++   + FE KL
Sbjct: 264 IDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKL 323

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYI-NRLLAPHITVDVNELTIVSVP 353
           ANI++PLE RRN  ++Y+PM + +L +  P + W ++  N +      V  +E+ +V  P
Sbjct: 324 ANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAP 383

Query: 354 KYITDLEALLEKTPKRVQA-----NYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
            ++ +L  ++ K  +  +      NY++W+      S L+   R        AL G
Sbjct: 384 DFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMG 439


>UniRef50_Q4RX51 Cluster: Chromosome 11 SCAF14979, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
           SCAF14979, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 831

 Score = 83.4 bits (197), Expect = 3e-15
 Identities = 58/172 (33%), Positives = 90/172 (52%), Gaps = 11/172 (6%)
 Frame = +3

Query: 6   LDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAIL------LGADKTKATEELKESLQ 161
           +DQ  LG+ SR+Y LN G   K+ +AY ++MV IA +      L  D  +  EE+ + L+
Sbjct: 267 IDQPGLGMPSRDYYLNDGNYKKVREAYLQFMVSIAKITRDDRNLTQDDDRLWEEMMQVLE 326

Query: 162 FEMKLANISLPLEKRRNATSLYNPMTIAELQQ--KFPKVPWLEYINRLLAP-HITVDVNE 332
            E  +AN + P E+R++ T LYN MTIAELQ    F    W  +I  +L+   I V + E
Sbjct: 327 LETDIANATSPAEERQDVTVLYNKMTIAELQNTFSFNGFNWTRFIQGVLSSVSIQVLLEE 386

Query: 333 LTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAY 488
             +V    Y+  +  +L K   R   NY+MW++    V+ L+   +  +  Y
Sbjct: 387 EVVVYSSPYLEKMNEVLPKHSVRTMQNYLMWQLIIDRVNSLSRRFKDARTRY 438


>UniRef50_Q22523 Cluster: Putative zinc metalloproteinase T16A9.4;
           n=2; Caenorhabditis|Rep: Putative zinc metalloproteinase
           T16A9.4 - Caenorhabditis elegans
          Length = 769

 Score = 83.0 bits (196), Expect = 4e-15
 Identities = 47/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
 Frame = +3

Query: 3   DLDQASLGLSREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 179
           +LDQ   G    Y    G +D +++ Y   M   A+ LGAD   A +E+ E+++FE+KL 
Sbjct: 247 ELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLV 306

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
           N S     RR+     N   + +L+  FP + + +Y+  +    + +  N   IV    Y
Sbjct: 307 NFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFKELVALSPNHTVIVREIDY 366

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLR 470
              ++ +L+ TPKRV ANY+ WR+      +L    R
Sbjct: 367 FVGIQHVLQSTPKRVLANYISWRLVQGFSPFLPPSAR 403


>UniRef50_O16796 Cluster: Neprilysin-2; n=4; Caenorhabditis|Rep:
           Neprilysin-2 - Caenorhabditis elegans
          Length = 848

 Score = 82.2 bits (194), Expect = 7e-15
 Identities = 53/184 (28%), Positives = 98/184 (53%), Gaps = 14/184 (7%)
 Frame = +3

Query: 6   LDQASLGLSRE----YLNRGFSDKLVQAYYEYMVDIAILLGAD------KTKATEELKES 155
           +DQ++L L R     YLN       + AY +Y+  IA LL  D      +++   ++++ 
Sbjct: 320 IDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKI 379

Query: 156 LQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAP----HITVD 323
           + FE++LA I +  ++RRN T LYN   I +L    P+V W+ +  + +AP    H+  +
Sbjct: 380 IDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFF-QSIAPSDLTHLFHN 438

Query: 324 VNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALS 503
             E+ I  + +Y+  +  L+EKT   +  NYV+WRV  ++V YL +     +  ++  ++
Sbjct: 439 ETEIIICEI-EYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMT 497

Query: 504 GKTE 515
           G+ +
Sbjct: 498 GQQQ 501


>UniRef50_A7REV1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 719

 Score = 81.4 bits (192), Expect = 1e-14
 Identities = 52/161 (32%), Positives = 82/161 (50%), Gaps = 4/161 (2%)
 Frame = +3

Query: 3   DLDQASLGLSREYLNRGFSD--KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           +LDQ+  G+S     R  S   K+  AY E MV++ + LG D + +  E+++  +FE KL
Sbjct: 206 NLDQSYPGISHRAFTRNSSTYRKMRHAYKELMVNLTMTLGGD-SHSLREMEDIYKFEKKL 264

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKF-PKVPWLEYINRLL-APHITVDVNELTIVSV 350
           ANI   LE        Y  M+I +LQ    P++ W+ ++  +       +   E  +V  
Sbjct: 265 ANI---LEPYVEGNKKYRKMSIRKLQNATGPQIDWMRFLTGVFRGVDYKIMEEEEVVVYA 321

Query: 351 PKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRR 473
             Y+  L  +LEKTPK+  ANY+MWRV       L+ + R+
Sbjct: 322 YDYLVKLAKILEKTPKKTLANYIMWRVVKIQYVQLSKEYRK 362


>UniRef50_A7RTG6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 806

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 51/157 (32%), Positives = 84/157 (53%), Gaps = 1/157 (0%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           +DQA+L L +  +    S K+V+    YM D+  L G DK     ++ E L+FE K+A I
Sbjct: 295 VDQATLNLPQ--IVYFTSPKIVKTVRNYMTDVICLAGYDKKDVKRKVHELLKFEAKIALI 352

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAP-HITVDVNELTIVSVPKYI 362
           S+P   ++     Y  + +++L +  P+ PW++++ +L AP  IT D     IV    Y+
Sbjct: 353 SVPKILKK-----YVRVPLSKLMKAVPEFPWMDHLKKLFAPKEITEDTK--VIVLANDYL 405

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRR 473
             L  LL  T K V ++Y+MWR+    V  L++  R+
Sbjct: 406 PKLFELLRNTDKDVLSDYMMWRLVKDVVPLLSNKFRK 442


>UniRef50_O44857 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 736

 Score = 76.2 bits (179), Expect = 4e-13
 Identities = 45/148 (30%), Positives = 79/148 (53%), Gaps = 8/148 (5%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           +DQ  L L +R++     +++ + AY + + D+ ILL AD+T+AT + KE + FE  LAN
Sbjct: 214 IDQPQLNLFARDFYVAAENEERM-AYLQLIRDVLILLDADRTRATLDAKEIIDFETALAN 272

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLL-------APHITVDVNELTI 341
           I++  E R +   LY  +T+ E+++  P   W  + NR+           IT D N   +
Sbjct: 273 ITMADEHRHDIAELYTKITLGEMRRSLPHFNWPLFFNRMFKDLHEKNGKRITFDDNTEVV 332

Query: 342 VSVPKYITDLEALLEKTPKRVQANYVMW 425
           V   +++  L+ L+ +   R+  NY+ W
Sbjct: 333 VYGYEFLRRLDVLIPQYDNRLIVNYLEW 360


>UniRef50_Q495T6 Cluster: Membrane metallo-endopeptidase-like 1 (EC
           3.4.24.11) (Membrane metallo-endopeptidase-like 2)
           (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m))
           [Contains: Membrane metallo-endopeptidase-like 1,
           soluble form (Neprilysin-2 secreted) (NEP2(s))]; n=61;
           Euteleostomi|Rep: Membrane metallo-endopeptidase-like 1
           (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2)
           (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m))
           [Contains: Membrane metallo-endopeptidase-like 1,
           soluble form (Neprilysin-2 secreted) (NEP2(s))] - Homo
           sapiens (Human)
          Length = 779

 Score = 76.2 bits (179), Expect = 4e-13
 Identities = 54/183 (29%), Positives = 95/183 (51%), Gaps = 11/183 (6%)
 Frame = +3

Query: 6   LDQASLGL-SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTK------ATEELKESLQ 161
           +DQ +LG+ SREY  N G + K+ +AY ++MV +A LL  D           E++ + L+
Sbjct: 251 IDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLE 310

Query: 162 FEMKLANISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP-HITVDVNE 332
            E +LA  ++P E+R +  +LY+ M + ELQ +F      W  +I  +L+   I +  +E
Sbjct: 311 LETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDE 370

Query: 333 LTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKT 512
             +V    Y+ +LE +++    R   NY++WR+    +  L+   +  ++ Y  AL G  
Sbjct: 371 EVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTM 430

Query: 513 ERE 521
             E
Sbjct: 431 VEE 433


>UniRef50_UPI0000F1FC7B Cluster: PREDICTED: similar to
           endothelin-converting enzyme 2B; n=4; Danio rerio|Rep:
           PREDICTED: similar to endothelin-converting enzyme 2B -
           Danio rerio
          Length = 705

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 42/131 (32%), Positives = 75/131 (57%), Gaps = 1/131 (0%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           +DQ+ L L SR+Y     ++K+++AY +YMV++ +LLG DK     ++++ L FE  LAN
Sbjct: 246 VDQSGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALAN 305

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           I++P ++RR+   +Y+ +TIA+LQ +      L     L +   T D+N +   +  +  
Sbjct: 306 ITVPQDERRDEEKIYHKITIADLQMESAASEILRSAEPLTS--FTADLNGIIEANWTRTE 363

Query: 363 TDLEALLEKTP 395
            ++   L K P
Sbjct: 364 ANVSCELSKIP 374


>UniRef50_O95672 Cluster: Endothelin-converting enzyme-like 1; n=13;
           Euteleostomi|Rep: Endothelin-converting enzyme-like 1 -
           Homo sapiens (Human)
          Length = 775

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 42/140 (30%), Positives = 78/140 (55%), Gaps = 2/140 (1%)
 Frame = +3

Query: 57  SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPL--EKRRNATSLYN 230
           S+K++ AY  +M  +  LLGAD  +  ++ +E LQ E +LANI++    + RR+ +S+YN
Sbjct: 283 SEKILAAYRVFMERVLSLLGADAVE--QKAQEILQVEQQLANITVSEHDDLRRDVSSMYN 340

Query: 231 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 410
            +T+ +LQ+  P + W   ++++     + +  E  ++    Y+  +  L+  TP RV  
Sbjct: 341 KVTLGQLQKITPHLRWKWLLDQIFQEDFSEE--EEVVLLATDYMQQVSQLIRSTPHRVLH 398

Query: 411 NYVMWRVAGASVSYLTDDLR 470
           NY++WRV      +L+   R
Sbjct: 399 NYLVWRVVVVLSEHLSPPFR 418


>UniRef50_A6L1Y4 Cluster: Putative endothelin-converting enzyme;
           n=1; Bacteroides vulgatus ATCC 8482|Rep: Putative
           endothelin-converting enzyme - Bacteroides vulgatus
           (strain ATCC 8482 / DSM 1447 / NCTC 11154)
          Length = 678

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 2/166 (1%)
 Frame = +3

Query: 18  SLGLSREYL-NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLP 194
           SLG    YL N   +  +   Y E++V +  L G D+  A ++++  +  E ++A  S  
Sbjct: 180 SLGEKEYYLDNDDVTVNIRNKYKEHIVKMFQLAGFDEAAAKKKMEAVMDIETRIAKASFS 239

Query: 195 LEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLE 374
             ++RN  + Y+ M++ EL+++ P + W  ++N +    +T    EL++  V + I ++E
Sbjct: 240 AVEQRNPAANYHKMSLDELKKEIPGIDWDAFLNGIGVKGVT----ELSVSQV-EPIKEVE 294

Query: 375 ALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQL-AYITALSGK 509
            ++   P   Q  Y+ W +   +  YL+DDL  +    Y   LSGK
Sbjct: 295 KIINSLPVENQIAYMQWSLIDRAAGYLSDDLVAQNFDFYGKTLSGK 340


>UniRef50_A6EJN3 Cluster: Probable metallopeptidase; n=1; Pedobacter
           sp. BAL39|Rep: Probable metallopeptidase - Pedobacter
           sp. BAL39
          Length = 677

 Score = 68.5 bits (160), Expect = 9e-11
 Identities = 41/151 (27%), Positives = 67/151 (44%)
 Frame = +3

Query: 57  SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 236
           S K+  AY EYMV +  L G    +AT +    +  E +LA   +   ++R+    YN  
Sbjct: 194 SVKIRGAYTEYMVSLFTLTGGTADEATRKATTVMAIEKQLAQAQMSRVEQRDPYKTYNKF 253

Query: 237 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANY 416
           T+A   +  P + W   +N L      V   +  +VS PK+   L+A+L+  P      Y
Sbjct: 254 TVAAFSKTTPNINWSTMLNNL-----KVTGQDTVLVSAPKFFVTLDAMLKSVPVADWKTY 308

Query: 417 VMWRVAGASVSYLTDDLRRRQLAYITALSGK 509
           + W V  ++   L+        A+  A SG+
Sbjct: 309 LEWNVLKSAAPNLSSPFVNASFAFSQAQSGQ 339


>UniRef50_Q9U9P2 Cluster: Endothelin converting enzyme; n=1; Hydra
           vulgaris|Rep: Endothelin converting enzyme - Hydra
           attenuata (Hydra) (Hydra vulgaris)
          Length = 770

 Score = 68.5 bits (160), Expect = 9e-11
 Identities = 45/146 (30%), Positives = 83/146 (56%), Gaps = 6/146 (4%)
 Frame = +3

Query: 9   DQASLGLSRE-YL-NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           DQ+ + L++E YL N  F     +AY +YM  IA  +GA++T   + + + ++FE +LAN
Sbjct: 255 DQSGISLAKESYLKNSTFHIGHREAYLKYMKSIAKQMGANET-GLKYMNDVMEFETQLAN 313

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVP--W-LEYINRLLAPHITVDVNELTIVSV- 350
           I++ +  RRN  S+Y  MT+ E   +  ++P  W L ++N +   +  + +    IVS  
Sbjct: 314 ITMSVLDRRNYHSIYESMTLEEFSNR-TEIPLSWLLRFVNNIFKENNLLVLPSERIVSFS 372

Query: 351 PKYITDLEALLEKTPKRVQANYVMWR 428
            ++I     L  + PK+ Q++Y++W+
Sbjct: 373 TQFIGKAYKLFNELPKKTQSSYIIWQ 398


>UniRef50_O93394 Cluster: Neprilysin; n=7; Euteleostomi|Rep:
           Neprilysin - Perca flavescens (Yellow perch)
          Length = 770

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/182 (30%), Positives = 85/182 (46%), Gaps = 15/182 (8%)
 Frame = +3

Query: 12  QASLGL-SREYLN-RGFSDKLVQAYYEYMVDIAILLGADK------TKATEELKESLQFE 167
           Q +LGL SR+Y    G   +  +AY ++M+D+A L+  D+      T   EE+K  +  E
Sbjct: 242 QTNLGLLSRDYYACTGPYAEACRAYEKFMIDLAKLIRIDRGLNISETDIREEVKRVMDLE 301

Query: 168 MKLANISLPLEKRRNATSLYNPMTIAELQQKFPK------VPWLEYINRLL-APHITVDV 326
             +AN +   E R N   LYN M + +L   F          W  +  +++   +I+V  
Sbjct: 302 RDIANATDTPEDRNNPVLLYNKMELGDLNANFTLEVESQVFDWSYFTAKIMDTVNISVPD 361

Query: 327 NELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
            E  I   P Y   L  +L +  KR   NY++WR A   V  L+   R  + A+  ALSG
Sbjct: 362 TEKVINYSPNYYRRLNLILARYNKRDLQNYMVWRFAMNMVVGLSRSYRDTRKAFRKALSG 421

Query: 507 KT 512
            T
Sbjct: 422 TT 423


>UniRef50_Q1BFQ6 Cluster: Neprilysin; n=19; Actinobacteria
           (class)|Rep: Neprilysin - Mycobacterium sp. (strain MCS)
          Length = 672

 Score = 62.1 bits (144), Expect = 7e-09
 Identities = 48/172 (27%), Positives = 77/172 (44%), Gaps = 3/172 (1%)
 Frame = +3

Query: 12  QASLGLSRE-YLNRGFSDKLVQAYYEYMVDI-AILLGADKTKATEELKESLQFEMKLANI 185
           Q+ +GL  E Y       +++ AY  ++  + A++ G D T+  E +   +  E KLA  
Sbjct: 163 QSGIGLPDESYFRDEQHAEILAAYPGHIAAMFALVYGGDHTQTAERI---VALERKLAAA 219

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRL-LAPHITVDVNELTIVSVPKYI 362
              + KRR+A   YN  T A+L  + P   W  ++  L   P    +V    +V  P Y+
Sbjct: 220 HWDVVKRRDADLTYNLRTFADLSAEAPGFDWAGWVTALGTTPESVAEV----VVRQPDYL 275

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTER 518
           T+  A     P     ++V WR+  A    LTD+L     A+   L   TE+
Sbjct: 276 TEFAAAWSSEPLEDWKHWVRWRLIHARAFLLTDELVAEDFAFYGRLLSGTEQ 327


>UniRef50_Q18673 Cluster: Neprilysin-1; n=3; Rhabditida|Rep:
           Neprilysin-1 - Caenorhabditis elegans
          Length = 754

 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 50/183 (27%), Positives = 81/183 (44%), Gaps = 12/183 (6%)
 Frame = +3

Query: 9   DQASLGL---SREY-LNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELK------ESL 158
           DQ SLGL   +R+Y L+    +K ++AY +Y +        D   A  E K      E +
Sbjct: 226 DQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEII 285

Query: 159 QFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPW--LEYINRLLAPHITVDVNE 332
            FE + A I +  E RRN T LYN     +L++    + W  L         H  +  N 
Sbjct: 286 AFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDWKKLTLSTTPFLVHSYLKTNP 345

Query: 333 LTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKT 512
             I+S  +Y+  +  LL+ T  R+  NY++ R AG+    +       Q  +   + G+ 
Sbjct: 346 SIIISDVEYLQKMNTLLQNTDPRIVTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRK 405

Query: 513 ERE 521
           +R+
Sbjct: 406 QRQ 408


>UniRef50_A5FLC8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=11; Bacteroidetes|Rep: Endothelin-converting enzyme 1
           precursor - Flavobacterium johnsoniae UW101
          Length = 698

 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 6/160 (3%)
 Frame = +3

Query: 6   LDQASLGLS-REYLNRGFSDKLVQAYYEYMVDIAILL---GADKTKATEELKESLQFEMK 173
           L   +LGLS ++Y N    D   +   +Y V +A +L   G    KA E  K+ +  E++
Sbjct: 189 LSPGTLGLSDKDYYNSDDKDSK-EKREKYEVHVARMLQYIGESPAKAKESAKQIVALEIE 247

Query: 174 LANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVP 353
           ++   L   +RR+    YNP  IA+L++  P + W +Y        I +   +   V+ P
Sbjct: 248 MSAPRLDRVERRDRRKQYNPTAIADLKKNTPSIQWEKYF-----AGIGITKLDTVNVAQP 302

Query: 354 KYITDLEALLEKTPKRVQA--NYVMWRVAGASVSYLTDDL 467
           +Y+T LE     T K+V+A   Y+ W +   + S L+ D+
Sbjct: 303 RYMTALEKTF--TEKKVEAWKEYLKWSLLNRTASTLSTDI 340


>UniRef50_A7S632 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 691

 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 3/129 (2%)
 Frame = +3

Query: 54  FSDKLVQAYYEYMVDIAILLGADKTKATEELKESL-QFEMKLANISLPLEKRRNATSLYN 230
           F  ++ + Y +YM D+ +LLG ++++A EE+ ES+ + E  LA + +    R  +++   
Sbjct: 190 FFFQIKKGYKKYMKDVLVLLGNNESRA-EEVSESIFRVEFALAQVKISQTARNESSTERQ 248

Query: 231 PMTIAELQQ-KFPKVPWLEYINRLL-APHITVDVNELTIVSVPKYITDLEALLEKTPKRV 404
            +++ +L      ++ WL +   +  A  IT  ++    V   KY  DL   +  TPK  
Sbjct: 249 LVSLKDLTHGNTSEINWLRFFTSVFKASTITPTMDFKVRVGFRKYFEDLPEYIRNTPKSD 308

Query: 405 QANYVMWRV 431
            ANY+MW++
Sbjct: 309 LANYMMWQI 317


>UniRef50_Q9A2Q2 Cluster: Peptidase M13 family protein; n=5;
           Proteobacteria|Rep: Peptidase M13 family protein -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 706

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 38/107 (35%), Positives = 51/107 (47%)
 Frame = +3

Query: 39  YLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNAT 218
           YL+  F+DK   AY  Y+  +  + G DK    E  K  + FE KLA ++    +RR+  
Sbjct: 219 YLDAKFADKKA-AYLAYVEKLLTMAGWDKP--AEHAKAVVDFETKLAEVTWTRAERRDRD 275

Query: 219 SLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
             YNP T+AELQ   P   W  YI     P +   V   T  + PKY
Sbjct: 276 KTYNPATLAELQAMSPGYDWNRYIAASGLPKVDRFV-VTTNTTFPKY 321


>UniRef50_A7SJV7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 603

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 33/159 (20%), Positives = 75/159 (47%), Gaps = 10/159 (6%)
 Frame = +3

Query: 60  DKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMT 239
           +K + AY +YM  + ++LG D T    ++++ ++ E +L+             SL+  + 
Sbjct: 181 NKTISAYIDYMAAVGLILGGDNTTTHRDMEDVIELEKQLSKACYLFPLLLFFHSLFFLLL 240

Query: 240 IAELQQKFPKVP---------WLEYINRLLAPH-ITVDVNELTIVSVPKYITDLEALLEK 389
           I ELQ+     P         + +Y+ +L   H + +  +E+  V   +Y+ ++  ++ +
Sbjct: 241 IKELQRTADLPPHYNTHVIFDFTDYLRKLFRKHGVVIGDDEIANVPSAEYLYNMTKIVRE 300

Query: 390 TPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
           T  R  +NY +W +    V +L+   R  +  ++  ++G
Sbjct: 301 TSNRTLSNYFIWTLLRNLVPFLSKPFREAEQTFLIRVAG 339


>UniRef50_A6S9J8 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 990

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 35/131 (26%), Positives = 63/131 (48%)
 Frame = +3

Query: 117 ADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINR 296
           A + KA +  ++ +  E KLA  S   E R + T  YNPM++ E  +  P++   + I+ 
Sbjct: 511 AAQDKAADLARDVVALEKKLAAASPNNEDRDDVTKTYNPMSLQEADKLTPQIHLSKIIHS 570

Query: 297 LLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRR 476
           L+   + +D     I++ P Y+  L  +L+ TPK     Y +W++     + +  D  + 
Sbjct: 571 LIPADVHLD---RLIIASPSYMHALADVLKTTPKETLQTYFVWKLIQTFYTEIEADELKP 627

Query: 477 QLAYITALSGK 509
              +I  L GK
Sbjct: 628 YRKFINELQGK 638


>UniRef50_A1D6I0 Cluster: Peptidase family M13 protein; n=7;
           Pezizomycotina|Rep: Peptidase family M13 protein -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 809

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 1/162 (0%)
 Frame = +3

Query: 27  LSREYLNRGFSDKLVQAYYEYMVDI-AILLGADKTKATEELKESLQFEMKLANISLPLEK 203
           L REY N   S + V  Y + + ++    +G DK  + E++   + FE KLAN +   + 
Sbjct: 306 LVREYYN---SSQTVSEYTKVLKEVLGNFVGQDKQVSVEDI---VLFESKLANATPDAQT 359

Query: 204 RRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALL 383
            ++    YNP    +++   P++     ++ L       D     IVS P Y+  L  +L
Sbjct: 360 LQDVEKYYNPRNFDQIESMLPQISLSTMVSALSPADFKTD---RLIVSSPSYMESLSTIL 416

Query: 384 EKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 509
            +TP++    +  W++  A V  + D        +   L+GK
Sbjct: 417 RETPRKTIHQFFKWKIIQAYVDQIEDAKITPLREFSNKLAGK 458


>UniRef50_Q8TPB2 Cluster: Endothelin converting enzyme-like protein
           PepO; n=2; Methanosarcina|Rep: Endothelin converting
           enzyme-like protein PepO - Methanosarcina acetivorans
          Length = 665

 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 45/176 (25%), Positives = 80/176 (45%), Gaps = 4/176 (2%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSD--KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           L Q  LGL  R++  R  S+  ++ + Y  ++  + + LG +   A    +  ++ E +L
Sbjct: 158 LTQGGLGLPDRDFYLRQDSESIRIREQYLTHVTRMFVFLGDNPETAENNARTVMRIETRL 217

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           AN S       +    YN M++ ELQ   P + W    + L  P    DV E+ + + P 
Sbjct: 218 ANASFNNVDDNDEVKTYNRMSLEELQVFAPGMNWSCLFSVLGRP----DVAEVNVRN-PS 272

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQL-AYITALSGKTERE 521
           Y  +L   L++        ++ W++  A+  YL+ DL +     Y   L+G+ E E
Sbjct: 273 YFKELSIALQEESTADWKTFLRWKLISATSPYLSSDLEKEHFDFYERKLNGQKEME 328


>UniRef50_Q0HFB8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=25; Proteobacteria|Rep: Endothelin-converting enzyme 1
           precursor - Shewanella sp. (strain MR-4)
          Length = 694

 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 41/151 (27%), Positives = 71/151 (47%), Gaps = 1/151 (0%)
 Frame = +3

Query: 72  QAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAEL 251
           +AY  ++  +  L G    KA+ E    L  E  +A+    + + R++T  YN   + +L
Sbjct: 217 KAYLAHIEKMFTLAGLANPKASAE--SILALETAIASKHWDVVETRDSTKTYNLYQVKDL 274

Query: 252 QQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRV 431
               P + W  Y+  L A   T D+    IV+ P YI  L  +L+ T       Y+ W+V
Sbjct: 275 PSLAPDIDWTGYLTTLGADKQT-DI----IVNQPSYIQGLNEVLKTTDLATWKTYMQWQV 329

Query: 432 AGASVSYLTDDLRRRQLAYIT-ALSGKTERE 521
              + S L+++L     A+ +  L+G+ E+E
Sbjct: 330 LTHAASNLSEELDNENFAFFSKTLNGQEEQE 360


>UniRef50_A5IAW9 Cluster: Metallopeptidase PepO, peptidase, M13
           family; n=4; Legionella pneumophila|Rep:
           Metallopeptidase PepO, peptidase, M13 family -
           Legionella pneumophila (strain Corby)
          Length = 678

 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 44/168 (26%), Positives = 77/168 (45%), Gaps = 3/168 (1%)
 Frame = +3

Query: 12  QASLGL-SREY-LNRGFSDKLV-QAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           Q  LGL  R+Y L +    K V +AY  ++  +  LLG     A +E K  +  E +LA 
Sbjct: 179 QGGLGLPDRDYYLKKEAKFKQVREAYVNHLTKMFELLGDSPEMAAKEAKIVMDIETQLAK 238

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
            S+   ++R+  ++Y+ MTI EL +  P   W +Y++      I   +N     ++P + 
Sbjct: 239 ASMSQVEQRDPHAIYHMMTITELDKLTPNFSWSQYLSARGQGKIK-KIN----FAMPDFF 293

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
             +  LL+         Y+ W +  A   YL+     +    ++AL+G
Sbjct: 294 KAMNELLQSVSLDEWKIYLRWHLIDAFAPYLSKPFVDQNFKMVSALTG 341


>UniRef50_Q4PB20 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 888

 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 29/93 (31%), Positives = 50/93 (53%)
 Frame = +3

Query: 147 KESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDV 326
           ++ ++ E +LA I+   E+  +  + YNP+   +L   F  + W +Y + L     TV  
Sbjct: 409 EQVVELERQLAKITPDSEEITDPVASYNPINSTKLAYTFSSISWNDYFSAL-----TVRT 463

Query: 327 NELTIVSVPKYITDLEALLEKTPKRVQANYVMW 425
            E  I+S PK++T L+AL+ +T   V   YV+W
Sbjct: 464 PETLILSSPKFVTSLDALISRTKTEVLEAYVVW 496


>UniRef50_A3CXD1 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Methanoculleus marisnigri JR1|Rep:
           Endothelin-converting enzyme 1 precursor -
           Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498
           / JR1)
          Length = 656

 Score = 55.6 bits (128), Expect = 7e-07
 Identities = 49/174 (28%), Positives = 75/174 (43%), Gaps = 4/174 (2%)
 Frame = +3

Query: 6   LDQASLGL-SREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           L Q  +GL  R+Y   N   S  L  AY E++  + +L G    +A  + K     E  L
Sbjct: 178 LYQGGIGLPDRDYYFRNDAGSPGLRDAYREHIARVLVLAGRSPEEAAADAKTVYAMEAAL 237

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           A   L  E+ R+     N  T+AEL++++P V W      L A   +  V  + +   P 
Sbjct: 238 AAAHLGREENRDPQKTANIHTLAELEERYPAVGW----GTLAAIPGSGSVGRVHVYQ-PG 292

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLA-YITALSGKTE 515
           Y+ +L++LL   P      Y+ +R+   +  YL         A Y T L G  E
Sbjct: 293 YVEELDSLLATAPLDDWKVYLRYRLIDQASPYLGASFEEEHFAFYETTLYGVPE 346


>UniRef50_UPI0000D56B83 Cluster: PREDICTED: similar to
           Endothelin-converting enzyme 2 (ECE-2); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           Endothelin-converting enzyme 2 (ECE-2) - Tribolium
           castaneum
          Length = 633

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 2/134 (1%)
 Frame = +3

Query: 36  EYLNRGFSDKL-VQAYYEYMVD-IAILLGADKTKATEELKESLQFEMKLANISLPLEKRR 209
           EY+  GF  K  ++AY +++ + +  L G  K    ++++E ++FEM LA         R
Sbjct: 176 EYILTGFEYKTELEAYEKWIYETVNHLSGGKKRINKDQIREIIKFEMYLATA-------R 228

Query: 210 NATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEK 389
           N  +     T+ +L QKF  + W+++++ +      +  N   IV    Y+  L  L+ +
Sbjct: 229 NNDARNERTTVEKLSQKF-SIDWIKFLDYIFGSFSIIAPNTTVIVKNYNYLKKLFLLVSQ 287

Query: 390 TPKRVQANYVMWRV 431
              RV  NY+MW V
Sbjct: 288 VGNRVARNYLMWSV 301


>UniRef50_UPI0000ECD566 Cluster: Kell blood group glycoprotein (EC
           3.4.24.-) (CD238 antigen).; n=2; Gallus gallus|Rep: Kell
           blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).
           - Gallus gallus
          Length = 658

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 39/154 (25%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
 Frame = +3

Query: 57  SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 236
           S K+++ Y  Y+  +  LLG  +         +L F   L  +  PL++RR    L+   
Sbjct: 167 SSKVLRVYLSYLEKLGDLLGGPQDGPPHSFSLTLSFISNLQRVVTPLQERRQRRMLFFHT 226

Query: 237 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPK-RVQAN 413
           TI ELQ+K P + WL  +  +  P + +++++   V    Y+ ++  L+E   K RV   
Sbjct: 227 TIRELQEKAPAIDWLSCLQAVFHP-MPMNLSQEIAVHDMDYLRNMSQLIEIWHKERVPHI 285

Query: 414 YVMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
           Y++  + G     L    +  +      L GK E
Sbjct: 286 YMIVCLVGNLSPALDSRFQDARQELSKILHGKME 319


>UniRef50_Q6F1M5 Cluster: Putative membrane metallo endopeptidase;
           n=1; Mesoplasma florum|Rep: Putative membrane metallo
           endopeptidase - Mesoplasma florum (Acholeplasma florum)
          Length = 632

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 3/170 (1%)
 Frame = +3

Query: 6   LDQASLGLS-REYLNRGFS--DKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           +D   LG+S R++        +++  AY  Y+ ++  L G  +    +       FE K+
Sbjct: 137 IDSMGLGMSDRDFYEETHPRHEEIKNAYKNYIENLVKLSGV-RLNTKDIFNLIYSFEEKI 195

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           +      E+ R   ++YN +TI EL    P V W EY+N+        D     I++ PK
Sbjct: 196 SKSMFKQEELREPENIYNVVTIKELNDICPIVDWTEYLNK-----TGYDKASKIILTEPK 250

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
           Y   L  ++E+       + + ++V  +    LT DL      Y +  SG
Sbjct: 251 YFEKLNQMIEEISLDDLKDIMSYKVTSSYSRMLTIDLYENSFKYGSVFSG 300


>UniRef50_P23276 Cluster: Kell blood group glycoprotein; n=33;
           Eutheria|Rep: Kell blood group glycoprotein - Homo
           sapiens (Human)
          Length = 732

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 27/109 (24%), Positives = 55/109 (50%)
 Frame = +3

Query: 63  KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 242
           ++ + Y  Y+  +  LLG D +K  E    S+    +L     PLE+RR    L+  +TI
Sbjct: 245 QIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTI 304

Query: 243 AELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEK 389
            +L++  P + WL  +     P +++  ++  +V   +Y+ ++  L+E+
Sbjct: 305 DQLKEMAPAIDWLSCLQATFTP-MSLSPSQSLVVHDVEYLKNMSQLVEE 352


>UniRef50_A4B5L9 Cluster: Metalloendopeptidase PepO; n=3;
           Bacteria|Rep: Metalloendopeptidase PepO - Alteromonas
           macleodii 'Deep ecotype'
          Length = 688

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 46/174 (26%), Positives = 82/174 (47%), Gaps = 4/174 (2%)
 Frame = +3

Query: 12  QASLGL-SREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           Q+ LGL  REY   +   S  +  AY +++  +  L G +  K + ++  +L  E K+A 
Sbjct: 188 QSGLGLPEREYYFDDDESSQTIRDAYVKHIQTMFELAGFEAPKESADMLFAL--ETKIAQ 245

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           + +  E+ RN  + YN +TI EL+   PK  W  Y    LA     D+  L I+    Y+
Sbjct: 246 LHMKKEQARNFAANYNKLTIEELKALMPKFDWDAY----LAEADVSDIPSLGILQ-KDYM 300

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQL-AYITALSGKTERE 521
            +++ ++ +T  +    ++ W +  AS   L+ +L       Y   L G  E++
Sbjct: 301 QNIDGVIAETSLKDWKTFLKWGLLNASAGRLSAELDEANFNFYSKVLRGVEEQQ 354


>UniRef50_Q9XZ14 Cluster: CG9634-PA; n=2; Sophophora|Rep: CG9634-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 879

 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 1/170 (0%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDK-LVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           LD+  LGL  +Y     +D+ +V+ Y   + D AI +G    +A     +   +E ++ N
Sbjct: 328 LDEGELGLPDKYFYGNDADEEVVRGYKLLLRDFAINMGIVSREADLFADDIFHYERRIVN 387

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
                +   N   +   M +A+L+ K P +P LE +  +  P   +  +   +V  P+ +
Sbjct: 388 HIEDAKADANRP-INKLMRLADLKIKAPSLPILESLQAIF-PKTKITEDTEVLVRDPEVM 445

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKT 512
             L  LL  + K+   N+++W +A   + +L+ + R     +  AL G+T
Sbjct: 446 HALSVLLSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRT 495


>UniRef50_A7SMH5 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 672

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 45/175 (25%), Positives = 77/175 (44%), Gaps = 9/175 (5%)
 Frame = +3

Query: 9   DQASLGLSREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           DQ+   LSRE +  N  +  K+  AY   M  +   LGA   +A   ++E  Q E++LA 
Sbjct: 152 DQSGTILSREAMLFNTTYHAKIRTAYRRIMTSLMEKLGAGN-EAEARMEEVYQLELELAK 210

Query: 183 IS-------LPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTI 341
           +        + L  +    +    + +A          +L +I  L   ++  D     +
Sbjct: 211 VKQRIQPSLIHLLSKVRQNNQPRTLKLAPPPSFLNLTDFLGHIFNLTDYNVKQDTE--VV 268

Query: 342 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSG 506
           V   +Y+ ++  +   TPKR+ ANY+MW VA    S L+ + R     Y  A++G
Sbjct: 269 VYAMEYMVNMSRIFANTPKRIVANYMMWHVAYFFASSLSKEFRDLYYEYREAITG 323


>UniRef50_Q1GSD1 Cluster: Endothelin-converting enzyme 1 precursor;
           n=3; Sphingomonadaceae|Rep: Endothelin-converting enzyme
           1 precursor - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 686

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 44/155 (28%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
 Frame = +3

Query: 63  KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 242
           KL  AY +++ ++  L G  +  A    K    FE ++A +        +AT +YN MTI
Sbjct: 208 KLQAAYLKHLENVLTLAG--EANAAARAKAIYDFEKQIATVHWDKNDSSDATKVYNKMTI 265

Query: 243 AELQQKFPKVPWLEYINRLLAPHITVDVNELT-IVSVPKYITDLEALLEKTPKRVQANYV 419
           AEL    P   W  ++         + VNE + +VS P   T    L+   P  V  + +
Sbjct: 266 AELAAAAPGFDWATFLR-------GIGVNEESLLVSQPSAFTGEAKLIADAPIGVIRDML 318

Query: 420 MWRVAGASVSYLTDDLRRRQLA-YITALSGKTERE 521
           + R        L D + R   A Y TALSG  + +
Sbjct: 319 IVRSLDGFSDVLPDAIAREAFAFYGTALSGTPQMQ 353


>UniRef50_A7JD61 Cluster: Putative uncharacterized protein; n=1;
           Francisella tularensis subsp. tularensis FSC033|Rep:
           Putative uncharacterized protein - Francisella
           tularensis subsp. tularensis FSC033
          Length = 701

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 1/154 (0%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKES-LQFEMKLAN 182
           + Q SLGL         ++K V+   +Y+  I  LL     K  EE  +  L  E  LA 
Sbjct: 198 ISQGSLGLPNRDYYLDENEKFVKIRNDYLEYIIKLLQQVNIKNPEEAAQKILSLETLLAE 257

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
           I     + R+   +YN   ++ L   +P + W  Y+     P    +  +  I+   +YI
Sbjct: 258 IQFSEVENRDPDKIYNKFKVSNLNDLYPYIEWNSYLKSAEIP----ETEKFIIIKQLRYI 313

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDD 464
             L  LL   P      Y+ +R+  A    L+++
Sbjct: 314 IGLGNLLNDIPLNTWKIYLKYRLVNAFAPLLSEN 347


>UniRef50_A0Q757 Cluster: M13 family metallopeptidase; n=6;
           Francisella tularensis|Rep: M13 family metallopeptidase
           - Francisella tularensis subsp. novicida (strain U112)
          Length = 687

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 1/155 (0%)
 Frame = +3

Query: 3   DLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKES-LQFEMKLA 179
           ++ Q SLGL         ++K V+   +Y+  I  LL     K  EE  +  L  E  LA
Sbjct: 183 NISQGSLGLPNRDYYLDENEKFVKIRNDYLEYIIKLLQQVNIKNPEESAQKILSLETLLA 242

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
            I     + R+   +YN   ++ L   +P + W  Y+     P    +  +  I+   +Y
Sbjct: 243 EIQFSEVENRDPDKIYNKFKVSNLNDLYPYIEWNSYLKSAEIP----ETEKFIIIKQLRY 298

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDD 464
           I  L  LL   P      Y+ +R+  A    L+++
Sbjct: 299 IIGLGNLLNDIPLNTWKIYLKYRLVNAFAPLLSEN 333


>UniRef50_UPI0000DB740C Cluster: PREDICTED: similar to F18A12.8a;
           n=1; Apis mellifera|Rep: PREDICTED: similar to F18A12.8a
           - Apis mellifera
          Length = 759

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 45/159 (28%), Positives = 74/159 (46%), Gaps = 8/159 (5%)
 Frame = +3

Query: 6   LDQASLGLSREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 179
           ++Q S G S  YL     F  +L++ Y  Y+ ++  L      ++ E   E L F   +A
Sbjct: 237 IEQVSPGFSEHYLVDPLRFRSELME-YKNYIKNMVELADVGN-ESIEFANEILNFTTNIA 294

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQ----KFPKVPWLEYINRLLA-PHITVDVN-ELTI 341
           +I    E+RR+   L    +I ELQQ       +  W +Y+  +    ++T+D+  +  I
Sbjct: 295 HIMATPEERRSVNHLIYDFSIDELQQWTDLHVQQWNWTKYLEAVFDNTNVTIDIKMDRVI 354

Query: 342 VSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLT 458
           V   KY+ +L  LL  TP      Y+ W +  A +S LT
Sbjct: 355 VMDLKYLQELPKLLAVTPFATIVRYIWW-ITYAGISPLT 392


>UniRef50_O52071 Cluster: Neutral endopeptidase; n=19;
           Lactobacillus|Rep: Neutral endopeptidase - Lactobacillus
           helveticus
          Length = 647

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 30/151 (19%), Positives = 68/151 (45%)
 Frame = +3

Query: 63  KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 242
           KL+    +  +++  + G  K +A   ++ +L F+ KL+ +    E+  +  ++YNP+++
Sbjct: 176 KLLDILEKQSINLLEMAGIGKEEARVYVQNALAFDQKLSKVVKSTEEWSDYAAIYNPVSL 235

Query: 243 AELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVM 422
            E   KF      +++  +L   +     E  IV  P+++   + L+          +++
Sbjct: 236 TEFLAKFKSFDMADFLKTILPEKV-----ERVIVMEPRFLDHADELINPANFDEIKGWML 290

Query: 423 WRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
            +   +   YL+ D R     +  A+SG  E
Sbjct: 291 VKYINSVAKYLSQDFRAAAFPFNQAISGTPE 321


>UniRef50_Q0FT66 Cluster: Probable zinc metalloproteinase; n=1;
           Roseovarius sp. HTCC2601|Rep: Probable zinc
           metalloproteinase - Roseovarius sp. HTCC2601
          Length = 693

 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 36/147 (24%), Positives = 64/147 (43%)
 Frame = +3

Query: 75  AYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQ 254
           AY  ++    +  G     A+    +++  E  L +  L   +R N    YNPMT+AE+Q
Sbjct: 211 AYRTFLAQTLMAAGYPAGDASRIAHDAVDIERVLHSGMLSPVERANPQMRYNPMTLAEVQ 270

Query: 255 QKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVA 434
            + P++   + + +   P     + ++ +VS P+Y+  L  LL   P     +Y+  RV 
Sbjct: 271 AQIPEIDLTDLLEQAGYPE---GIEDVVLVS-PRYLPVLSELLRTRPFEEIKDYLKLRVI 326

Query: 435 GASVSYLTDDLRRRQLAYITALSGKTE 515
                 ++        A+  AL G TE
Sbjct: 327 LTFAPVMSTAFEEANQAFNAALLGSTE 353


>UniRef50_UPI0000F2E41E Cluster: PREDICTED: similar to Kell blood
           group, metalloendopeptidase,; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to Kell blood group,
           metalloendopeptidase, - Monodelphis domestica
          Length = 768

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 27/109 (24%), Positives = 53/109 (48%)
 Frame = +3

Query: 63  KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 242
           ++++AY  Y+  +  LLG D+    E    S+     L  ++ PL + +    L    TI
Sbjct: 278 QILRAYVSYLEQLGTLLGGDQKVVLEHAYLSITITSNLLMVANPLVQEKTEDKLIQETTI 337

Query: 243 AELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEK 389
           A+LQ+  P + WL  +  + +  +T+  ++  IV    YI  +  ++E+
Sbjct: 338 AQLQEMAPSIDWLSCLQAVFSV-MTLSPSQPIIVHDLDYIKGMSQVIEQ 385


>UniRef50_A0KHJ6 Cluster: Peptidase, M13 family; n=2; Aeromonas|Rep:
           Peptidase, M13 family - Aeromonas hydrophila subsp.
           hydrophila (strain ATCC 7966 / NCIB 9240)
          Length = 681

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 49/172 (28%), Positives = 75/172 (43%), Gaps = 5/172 (2%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYE-YMVDIAILLGA-DKTKATEELKESLQFEMKL 176
           L QA LGL  R+Y  +  +D   QA  + Y   IA +LG   +  A  + K  L  E KL
Sbjct: 179 LYQAGLGLPDRDYYLK--TDAASQALRQKYEQHIATMLGRFGEADAGAKAKRILALESKL 236

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRL-LAPHITVDVNELTIVSVP 353
           A I       R+    YN    +EL++  P + W  Y+ +  LA   ++      I+  P
Sbjct: 237 ARIQWDNVTLRDREKNYNKGPQSELKRLAPAIDWNAYLTQAGLAGQSSL------IIGQP 290

Query: 354 KYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYI-TALSG 506
            Y+  L  ++++TP      Y+ W +      YL      +  A+  T LSG
Sbjct: 291 TYLAALNEVMQQTPVGDWQAYLKWHLITDYAPYLDSQTDAQNFAFFGTTLSG 342


>UniRef50_Q139J8 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Rhodopseudomonas palustris BisB5|Rep:
           Endothelin-converting enzyme 1 precursor -
           Rhodopseudomonas palustris (strain BisB5)
          Length = 678

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 4/174 (2%)
 Frame = +3

Query: 12  QASLGL-SREY-LNRGFS-DKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           QA LGL SREY L  G   D    AY  Y+ DI   +G       +  K  L FE +LA 
Sbjct: 175 QAGLGLPSREYYLTAGEPFDGHRAAYLAYVADIFKRVGV--ADGGDRAKAILAFETRLAE 232

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
                 ++R+    Y  ++IAELQ   P  PW  Y+        T    EL +++    I
Sbjct: 233 AQWTAAEQRDPVKSYRLLSIAELQAYAPAFPWQIYLEAAGFSRPT----EL-VLTTDTAI 287

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAY-ITALSGKTERE 521
                + + T      +Y+ + +       LT++L R   A+  T L G  E+E
Sbjct: 288 QKSAEIFKATDIETIKSYLAFHLVDDFAPNLTEELDRASFAFNSTRLHGVPEQE 341


>UniRef50_UPI0000DB6F34 Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to mel transforming oncogene-like 1 -
           Apis mellifera
          Length = 762

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 10/120 (8%)
 Frame = +3

Query: 141 ELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFP---------KVPWLEYIN 293
           ++ E L FE++L  I    ++    +  +  MTI +LQ+ +          K+ +LE I 
Sbjct: 272 DIVEMLYFELELLEIIENGKESHTVSDNFERMTIEQLQKWYDNSGVNTSTAKIDFLEMIQ 331

Query: 294 -RLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLR 470
                 +I ++ +E  IV  P ++  L +LL KT +RV  NY+ W +    + Y T ++R
Sbjct: 332 YSFKMANIDINSSEPIIVYNPIFLHKLASLLGKTSRRVLVNYIQWNMIDKFLLYTTQEMR 391


>UniRef50_A0QP11 Cluster: Metallopeptidase; n=8;
           Actinomycetales|Rep: Metallopeptidase - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 666

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 45/170 (26%), Positives = 64/170 (37%), Gaps = 3/170 (1%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVD--IAILLGADKTKATEELKESLQFEMKLA 179
           + Q+ +GL  E   R      + A Y   +     ++ G D T     +   +  E K+A
Sbjct: 160 MGQSGIGLPDESYFRDEQHAEILAGYPVHIAKMFGLIYGGDHTDTAARI---VALESKIA 216

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
                + KRR+A   YN    A+L  + P   W  ++  L     T D     +V  P Y
Sbjct: 217 AAHWDVVKRRDADLTYNLRRFADLPAEAPGFDWSGWVQGL---GTTPDTVAELVVRQPDY 273

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLA-YITALSG 506
           +T    L           +  WRV  A    LTDDL     A Y   LSG
Sbjct: 274 LTAFAGLWASEDLEDWKAWARWRVIHARAGLLTDDLVAEDFAFYGRTLSG 323


>UniRef50_A4R2H0 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 779

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 2/132 (1%)
 Frame = +3

Query: 60  DKLVQAYYEYMVDIAILLGADKTKATEELKESL-QFEMKLANISLPLEKRRNATSLYNPM 236
           D +V AY + M  +   +  + T   + L ES+ + E  +A I+  L + R+ T  YN M
Sbjct: 283 DSVVSAYQDAMQQVLKSVLPNATTEAKGLAESIVKLEKDIAAITPSLSQLRDVTKTYNVM 342

Query: 237 TIAELQQKFPKVPWLEYINRLLAP-HITVDVNELTIVSVPKYITDLEALLEKTPKRVQAN 413
           ++ +  +  P++  ++ + + LAP + T+D     I + P+++ ++  +L  T       
Sbjct: 343 SLQDTAKLAPQL-GIDKVLKALAPSNYTID---RMITAYPEFLGNVSQILSSTKAETVKG 398

Query: 414 YVMWRVAGASVS 449
           ++ W+V  A  S
Sbjct: 399 FLQWKVIQALAS 410


>UniRef50_UPI00015B5D2D Cluster: PREDICTED: similar to
           Endothelin-converting enzyme 1; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           Endothelin-converting enzyme 1 - Nasonia vitripennis
          Length = 701

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 11/144 (7%)
 Frame = +3

Query: 72  QAYYEYMVDI--AILLGADKTKATEELKESLQFEMKLA-NISLPLEKRRNATSLYNPMTI 242
           + Y E+M ++  A L  ++KT + +++   ++  +K++ N +  +E  R   ++ +  + 
Sbjct: 213 EKYAEFMKNVVNAFLKSSNKTLSDDDISRDVEDILKVSDNETSDMEPPRTYMTIDDLQSF 272

Query: 243 AELQ---QKFPKVPWLEYINRLLA---PHITVDVNELTIVSV-PKY-ITDLEALLEKTPK 398
              +   +   K+ WL+ I  L         +++ EL  + +  KY +  L  LLEKTP 
Sbjct: 273 YNEENPTKPTSKINWLQTIRALFRNVNKSENIEIGELEEMGIGDKYFLHGLLHLLEKTPN 332

Query: 399 RVQANYVMWRVAGASVSYLTDDLR 470
           RV  NYV W+    S+ +   ++R
Sbjct: 333 RVIVNYVHWKFVSTSIKFTNKEMR 356


>UniRef50_A5KV97 Cluster: Peptidase, M13 family protein; n=1;
           Vibrionales bacterium SWAT-3|Rep: Peptidase, M13 family
           protein - Vibrionales bacterium SWAT-3
          Length = 808

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 2/150 (1%)
 Frame = +3

Query: 12  QASLGLSRE--YLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           Q+ LGL  E  YL+  +  KL+  Y  ++     +  A+     ++    +  E  +A  
Sbjct: 315 QSGLGLPSENIYLSPKYK-KLMHGYLNHIGKAFEM--ANMVAPYDQASLVVSLETDIATF 371

Query: 186 SLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYIT 365
            +P EK  +  ++ NP TI EL ++   + W  Y + L AP ++      T++ +P + T
Sbjct: 372 FMPAEKMSDRKNMINPRTIEELNKESSNINWTLYFSSLNAPKLS-----HTLLGMPDFTT 426

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYL 455
           +++ L +         Y  W++  +   Y+
Sbjct: 427 NIDWLSKPELMSSWRAYFKWQLINSYSPYI 456


>UniRef50_A3UFI2 Cluster: Secreted zinc metalloproteinase; n=4;
           Hyphomonadaceae|Rep: Secreted zinc metalloproteinase -
           Oceanicaulis alexandrii HTCC2633
          Length = 697

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 4/175 (2%)
 Frame = +3

Query: 6   LDQASLGLSRE--YLNRGFS-DKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           L Q  LG+     YL+ G    +   AY  Y+  I  L G +  +  E+ +  L FE ++
Sbjct: 193 LFQGGLGMGNRDYYLDEGERFQQYRDAYVAYIARIFELSGIEGGQ--EKAEAILAFETRI 250

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           A+     E  R+ T  YN M++AEL +  P + + E +      ++ ++V+EL +V  P 
Sbjct: 251 ADAHWTREDSRDVTLTYNVMSVAELDELAPALNFPEGM-----ANLGLNVDELIVVQ-PT 304

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYI-TALSGKTER 518
            I    A+LE T      +++ +        +L  +       +    L G+TE+
Sbjct: 305 AIAQTSAILEDTDLETIKDWMAFNFISDRAGWLPTEFEDANFDFFGRTLRGQTEQ 359


>UniRef50_Q6UEA5 Cluster: Zinc metallopeptidase 6; n=5;
           Ancylostoma|Rep: Zinc metallopeptidase 6 - Ancylostoma
           ceylanicum
          Length = 902

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 38/162 (23%), Positives = 75/162 (46%), Gaps = 12/162 (7%)
 Frame = +3

Query: 6   LDQASLGLSRE-YLNRGFSDKLVQA---YYEYMVDIAILLGADKTKATEELKES----LQ 161
           + Q SL + RE Y+   F+ KL +      + +   A  +  D     +E+K++    +Q
Sbjct: 326 ISQPSLPMPREFYVLPQFTKKLQEREKLLRDVLFKFADTILDDPEPYAKEIKKAALDIVQ 385

Query: 162 FEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDV--NEL 335
            E ++A  S P  + RN    YN   + +L++ +PK+ W  Y+N L++     D   +  
Sbjct: 386 LERRIAMASWPKTQLRNYAQQYNAYKLRDLKKTYPKINWDSYLNALMSTAGKPDFSGSAR 445

Query: 336 TIVSVPKYITDLEALL--EKTPKRVQANYVMWRVAGASVSYL 455
            +++ P Y   L AL+       ++  NY++ ++      +L
Sbjct: 446 LVIAQPSYFGWLNALVSGNTVDDKMLVNYMITQLIFEDADFL 487


>UniRef50_Q9VAS0 Cluster: CG14527-PA; n=3; Sophophora|Rep:
           CG14527-PA - Drosophila melanogaster (Fruit fly)
          Length = 700

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 29/107 (27%), Positives = 55/107 (51%)
 Frame = +3

Query: 111 LGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYI 290
           LG     A +  KE  +FE+ LA+  +   K  N   L   +T+AEL++++   P L+  
Sbjct: 235 LGVKDELARKAAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELRERY--APTLD-T 291

Query: 291 NRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRV 431
           ++L+   +   +++       +Y  +L  ++E+TPK   ANY+  R+
Sbjct: 292 DQLIFVSMGEKISDKVYEYNRRYQQNLVEVIERTPKSTVANYLFLRL 338


>UniRef50_A7S9L3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 788

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 5/147 (3%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           + + S  LSR  L    +D  V+ AY  Y+   AIL   + + +  ++ E + FE ++AN
Sbjct: 207 ISEPSFRLSRADLKA--ADPTVRNAYRTYIT--AILSAVNSSVSAADIDEIIAFEQQIAN 262

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKF--PKVPWLEYINRLLAP--HITVDVNELTIVSV 350
           I            LY+ +T+ E   +    +V W   +  + +   ++  D   + +  +
Sbjct: 263 IM----DSSGYAPLYDRITLNEFVTRVGTEQVNWSNLLRGVFSDVGYVVGDSTTVVVHGM 318

Query: 351 PKYITDLEALLEKTPKRVQANYVMWRV 431
           P ++  L +L++ TPKR  AN+++W++
Sbjct: 319 P-FLKSLMSLIQSTPKRTLANFLVWQI 344


>UniRef50_Q7NQ35 Cluster: Probable metallopeptidase; n=1;
           Chromobacterium violaceum|Rep: Probable metallopeptidase
           - Chromobacterium violaceum
          Length = 642

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 46/170 (27%), Positives = 62/170 (36%), Gaps = 2/170 (1%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLG-ADKTKATEELKESLQFEMKLAN 182
           + Q+ L + R+Y   G S     A   Y   +A LL  A +  A       L  E +LA 
Sbjct: 140 VSQSGLAMDRDYY-LGQSADFAAARKAYQAYLARLLALAGEKDAQPRAAAVLALETRLAQ 198

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYI 362
                   R+A   YN     EL  K P   W   +          D+N    +  P Y+
Sbjct: 199 AQWSNVDNRDAQKTYNKTAAGELAGKLPGYDWPALLKDAQLA-AAADLN----LDQPSYL 253

Query: 363 TDLEALLEKTPKRVQANYVMWRVAGASVSYLTDD-LRRRQLAYITALSGK 509
             L ALL  TP     +Y+  R   A   YL    +  R   Y  AL G+
Sbjct: 254 EQLPALLRATPLPALRDYLTLRTLDAYAPYLDKPWVAARFAFYGKALDGR 303


>UniRef50_Q6L063 Cluster: Zinc metalloprotease; n=2;
           Thermoplasmatales|Rep: Zinc metalloprotease -
           Picrophilus torridus
          Length = 634

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 3/175 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLAN 182
           + Q  L L  R+Y        ++  + +++ ++  +LG      + + +  +  E  LA 
Sbjct: 147 ISQGGLSLPDRDYYINDMFSGVISKFNDHVKNMMDILGY-----SIDYRNLINIEKSLAE 201

Query: 183 ISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVN-ELTIVSVPKY 359
            S   E  R+   LYN M+I +L +++  +    Y+N L        VN +  IV+ P Y
Sbjct: 202 HSKSREDLRDLEKLYNKMSIKDLDERYNNLGISRYLNSL-------GVNADYAIVATPDY 254

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYI-TALSGKTERE 521
           ++ L   ++         Y  W    A   YL++D       +    L+GK + E
Sbjct: 255 LSFLNGFIKDVDINDIKEYFKWHAINAYAPYLSNDFVMENFNFFGKILTGKEKIE 309


>UniRef50_Q88SH6 Cluster: Endopeptidase PepO; n=10;
           Lactobacillales|Rep: Endopeptidase PepO - Lactobacillus
           plantarum
          Length = 638

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 32/152 (21%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
 Frame = +3

Query: 63  KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTI 242
           KL+  Y + M ++    G +K +A + + ++LQF+  +       E+  + + +YNP   
Sbjct: 163 KLLAIYAKMMTELLQKTGYEKDEAQKIVDDTLQFDRLIVPWIKSAEESADYSKMYNPRKF 222

Query: 243 AELQQKFPKVPWLEYINRLLAPHITVDVN-ELTIVSVPKYITDLEALLEKTPKRVQANYV 419
            +       V    Y++     +  +D N +L I+  P +      ++      +  N++
Sbjct: 223 NDF------VNTSRYLDLAAITYSVIDGNPDLVILPEPAFFDHFNEVVNPDNFGLMKNWM 276

Query: 420 MWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
             ++      YL+D++R     Y  ALSG+ E
Sbjct: 277 KAKLVQRYSGYLSDEMRVLATTYSRALSGQKE 308


>UniRef50_Q5FPC6 Cluster: Metalloprotease; n=1; Gluconobacter
           oxydans|Rep: Metalloprotease - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 698

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 24/84 (28%), Positives = 41/84 (48%)
 Frame = +3

Query: 39  YLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNAT 218
           Y N   +DK  +AY  Y+  +  L G     A +  +  +  E  LA + +P ++ R+  
Sbjct: 207 YTNPKLADKK-KAYQAYIAKMLTLEGWPD--AEKNAQAVVDLETALAKVEVPRDQTRDPI 263

Query: 219 SLYNPMTIAELQQKFPKVPWLEYI 290
             YNPM ++ELQ+  P   W  ++
Sbjct: 264 KTYNPMPVSELQKLAPDFDWATFL 287


>UniRef50_A6ENN0 Cluster: Putative endopeptidase; n=1; unidentified
           eubacterium SCB49|Rep: Putative endopeptidase -
           unidentified eubacterium SCB49
          Length = 675

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 41/175 (23%), Positives = 71/175 (40%), Gaps = 3/175 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSD--KLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           L Q  LGL  R+Y     +   ++ +AY +Y+  +  L G +   A +        E +L
Sbjct: 176 LGQTGLGLPDRDYYFGEDTSVIEIQEAYLQYITSLFELTGQEH--AGKMANVVFNIEKQL 233

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           A       +RR+    YN  T+  L ++   + W    N L     T+DV +      P 
Sbjct: 234 AASHKTRIERRSIKDNYNKWTLEALDKRNKNISWASIFNTLGMDITTLDVRQ------PV 287

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERE 521
           Y   L+ +L + P      Y+      +  + L    +    AY   LSG++E++
Sbjct: 288 YYDTLDKMLSQVPLEQWKTYLKANSIKSHATILGKPFQDASFAYSKILSGQSEQQ 342


>UniRef50_UPI00015B4306 Cluster: PREDICTED: similar to
           ENSANGP00000001161; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000001161 - Nasonia
           vitripennis
          Length = 807

 Score = 42.3 bits (95), Expect = 0.006
 Identities = 22/83 (26%), Positives = 38/83 (45%)
 Frame = +3

Query: 264 PKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGAS 443
           PKV W  ++  LL   +  D     ++    Y+ ++  +L  T   +    + W V   S
Sbjct: 374 PKVFWKPFVQELLRGIVDFDPEMKVLIGDLDYLKEVAVVLASTEDELLETAIWWTVVDYS 433

Query: 444 VSYLTDDLRRRQLAYITALSGKT 512
           V Y + +LR+   AYI  L+G +
Sbjct: 434 VPYSSQELRKIWNAYIDDLTGSS 456


>UniRef50_UPI0000DB770B Cluster: PREDICTED: similar to mel
           transforming oncogene-like 1; n=1; Apis mellifera|Rep:
           PREDICTED: similar to mel transforming oncogene-like 1 -
           Apis mellifera
          Length = 503

 Score = 42.3 bits (95), Expect = 0.006
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
 Frame = +3

Query: 123 KTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFP--KVPWLEYINR 296
           K++  E++++   FE KL  IS  ++   N T          L  +    KV W + I  
Sbjct: 212 KSQLEEDIEDIFSFEWKLLKISSLVDDYVNMTVGDFQRWYDHLNPRTENSKVNWTDKIIN 271

Query: 297 LLAPHITVDVNELTIVSV--PKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLR 470
           +      +D++  T+V +  P Y  +L  LL++T  R   N++ W    + ++  TD++R
Sbjct: 272 IFK-ETGIDISNDTLVKITSPGYFKNLVPLLDETSTRTIVNFLHWSFVSSMITRTTDEMR 330


>UniRef50_Q74M04 Cluster: Endopeptidase O; n=2; Lactobacillus|Rep:
           Endopeptidase O - Lactobacillus johnsonii
          Length = 577

 Score = 42.3 bits (95), Expect = 0.006
 Identities = 29/153 (18%), Positives = 65/153 (42%)
 Frame = +3

Query: 57  SDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPM 236
           S++L+  + +    +  L G     + +    +++F+ KLA      E+  +  S+YN  
Sbjct: 173 SEELLNTFEKQSAKLLTLAGLSSEDSKQIATNAVRFDKKLAKHKKSQEEINDFASMYNAY 232

Query: 237 TIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANY 416
           +  +    F  +   + +N L +      V E  IV  P Y+  +  L+         ++
Sbjct: 233 STQQFASSFEFLDIEQLLNSLFSK-----VPEKIIVIEPDYLKHINELVNPENFEELKSW 287

Query: 417 VMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
           ++ +   +S  YL+++ ++    Y  A+ G  E
Sbjct: 288 ILVKFVNSSADYLSEEFQKAAFPYKQAVEGVRE 320


>UniRef50_Q7VPA2 Cluster: Metallopeptidase; n=2;
           Pasteurellaceae|Rep: Metallopeptidase - Haemophilus
           ducreyi
          Length = 723

 Score = 41.5 bits (93), Expect = 0.011
 Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 3/164 (1%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDK--LVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLA 179
           L  + LGLS +Y  +   +    +  Y +Y+  I  +  A     T      + +E ++A
Sbjct: 218 LANSDLGLSNDYFQKDTPENRATLAQYQDYIRQILTI--AKVPNPTASAAAIVAYEKEMA 275

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVN-ELTIVSVPK 356
           N     E+ R+    YNP+ + +L      +   +Y+         V VN E  I+  P+
Sbjct: 276 NTLFTNEEERDMQKRYNPVAMKDLANLSQHINLADYLE-------AVGVNTEEVILWEPR 328

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAY 488
           Y   L+ L+      V  +Y++++    +  YL   L   + A+
Sbjct: 329 YFQALDKLINPQKLAVIKDYLLFKTLSENAGYLHKKLDDMKFAF 372


>UniRef50_Q2FS56 Cluster: Endothelin-converting enzyme 1; n=1;
           Methanospirillum hungatei JF-1|Rep:
           Endothelin-converting enzyme 1 - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 706

 Score = 41.5 bits (93), Expect = 0.011
 Identities = 32/147 (21%), Positives = 62/147 (42%), Gaps = 3/147 (2%)
 Frame = +3

Query: 84  EYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLE-KRRNATSLYNPMT--IAELQ 254
           EY+    +  G D+ KA        + E ++A   + +     N++      T  +A+L+
Sbjct: 225 EYVTTTFMEQGMDREKALHAADVVFRIERRMAQAEMGMNTSHANSSEELKAGTYQVADLR 284

Query: 255 QKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVA 434
             FP + W   + R   P    D+ E+ I++ P Y+ ++  +L   P      ++ WRV 
Sbjct: 285 TLFPGISWDALLERSGRP----DLQEIYIMN-PHYLREVGRILSSEPVEDLKLFLTWRVL 339

Query: 435 GASVSYLTDDLRRRQLAYITALSGKTE 515
             +  Y T +++ R   +      K E
Sbjct: 340 QYAAPYATPEMQERYYEFYDVKLSKGE 366


>UniRef50_UPI00003C85BA Cluster: hypothetical protein Faci_03000131;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000131 - Ferroplasma acidarmanus fer1
          Length = 663

 Score = 41.1 bits (92), Expect = 0.015
 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKES-LQFEMKLA 179
           L+Q  L L +R+Y       ++   Y  ++ ++ IL G D  K +E +  + L+ E  LA
Sbjct: 162 LNQDGLSLPNRDYYFDDSFKEIRAQYINHIKNMFILYGFDD-KTSENMGNTVLKIETSLA 220

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
             S    + R+    YN     +++++FP +   EY ++     I +   +  I+  P++
Sbjct: 221 LKSRSPVELRDPDKNYNRFQFNDIEKEFPGLRHREYFSK-----IGLTGLDYIIIGQPEF 275

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDL 467
             DL++++++        Y+ W V  ++  +L  D+
Sbjct: 276 FRDLDSIIQQYTLDDWKIYMKWNVLNSAAPFLFGDV 311


>UniRef50_A3CP78 Cluster: Metalloendopeptidase, putative; n=1;
           Streptococcus sanguinis SK36|Rep: Metalloendopeptidase,
           putative - Streptococcus sanguinis (strain SK36)
          Length = 689

 Score = 41.1 bits (92), Expect = 0.015
 Identities = 35/159 (22%), Positives = 71/159 (44%)
 Frame = +3

Query: 39  YLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNAT 218
           Y + G   +++    +   +    LG  +  + + +KE+L+F+ +LA  +   E+     
Sbjct: 207 YEDEGAKKRMMDPLEKAFKEALQKLGYSEKNSEKIVKEALEFDGELAKYAQSNEETSEIK 266

Query: 219 SLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPK 398
           +L++P T  ++        + + IN  L    + DVN    V  PKY  +   ++     
Sbjct: 267 NLHHPKTAEDINAYSDTFKFHDIINDYLGQE-SGDVN----VPNPKYYENFAKVVNDKNF 321

Query: 399 RVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
               ++++ + A ++ S+LTDD R     Y  +L G  E
Sbjct: 322 GKLKSWMLVKQAASASSFLTDDYRLIFAEYQKSLQGTKE 360


>UniRef50_A7SWD6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 693

 Score = 41.1 bits (92), Expect = 0.015
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
 Frame = +3

Query: 90  MVDIAILLGADKTKATEELKESLQFEMKLANISLP-------LEKRRNATSLYNPMTIAE 248
           M +I   LGAD+    + L + ++FE +L   +LP       +   R+   L +P++ + 
Sbjct: 217 MKNITNALGADQVALAKWLPQVIRFERRLEKAALPDNSITTEVMSIRDFQLLVDPISSSS 276

Query: 249 LQQKFPKVPWLEYINRLLAP-HITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMW 425
             Q    + W   +  + +     +  N   IV+  +Y   +   L+KTPK+  ANY+ W
Sbjct: 277 NLQ----IDWQNLLQEIFSDTQYQITSNTKIIVNGLRYFKKMIKYLKKTPKQTIANYLTW 332

Query: 426 RVA 434
           ++A
Sbjct: 333 KLA 335


>UniRef50_A3HSZ7 Cluster: Metalloendopeptidase PepO; n=3;
           Bacteroidetes|Rep: Metalloendopeptidase PepO -
           Algoriphagus sp. PR1
          Length = 674

 Score = 40.7 bits (91), Expect = 0.020
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 3/174 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKL-VQ-AYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           L Q  LGL  R+Y  +  S  L +Q AY  Y+  +  L G+   +A +  ++    E  L
Sbjct: 173 LRQTGLGLPDRDYYFKSDSSTLGIQNAYKTYIATLFELTGSSSGEAAQASEDVYAIEKAL 232

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           A       +RR     Y+ + +++L++K P +     I  +L   + +D + L  V  P 
Sbjct: 233 AESHKTRIERRVVKENYHKLAVSDLEKKQPNLG----IESILGD-LGLDADSLD-VRQPA 286

Query: 357 YITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTER 518
           Y   L  LL          Y+         SYL+         Y   +SG++++
Sbjct: 287 YYEKLNNLLASVSLADWKTYLKAHTLSTYASYLSTPFENASFEYSKVVSGQSKQ 340


>UniRef50_Q22763 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 798

 Score = 40.7 bits (91), Expect = 0.020
 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 4/108 (3%)
 Frame = +3

Query: 111 LGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYI 290
           +GAD   A  +  E + FE+++A  S P +  RN    YNP  IA     +  + W  Y+
Sbjct: 269 VGADALLAAAQ--EVVNFEVQIAMASWPDDLLRNYQQQYNPYNIASATTAYRAINWKSYL 326

Query: 291 NRLL--APHITVDVNELTIVSVPKYITDLEALLE-KTP-KRVQANYVM 422
            +L           N   +V+ P Y   L ++ + KT    V ANY++
Sbjct: 327 GQLFHGVASDADQANYNIVVTEPSYFAWLNSVFDGKTSNSTVVANYMI 374


>UniRef50_UPI0000E48FBC Cluster: PREDICTED: similar to
           endothelin-converting enzyme; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           endothelin-converting enzyme - Strongylocentrotus
           purpuratus
          Length = 473

 Score = 40.3 bits (90), Expect = 0.026
 Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
 Frame = +3

Query: 261 FPKVPWLEYINRLL-APHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAG 437
           FP + WL Y+  L     I +  +E  +V  P ++ D+  L+  +   V  NY++WR+  
Sbjct: 46  FP-IDWLSYLQFLFNGTDIEITKDEPIVVYAPDFLQDMSNLILSSDPIVVHNYMIWRLVT 104

Query: 438 ASVSYLTDDLRRRQLAYITALSGK 509
           + ++ L+   R+    +   LSGK
Sbjct: 105 SLMNLLSAAFRQADHDFDQVLSGK 128


>UniRef50_A7RTG5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 751

 Score = 40.3 bits (90), Expect = 0.026
 Identities = 20/63 (31%), Positives = 36/63 (57%)
 Frame = +3

Query: 6   LDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANI 185
           +DQA+L +   Y       ++V+   +YM D+  L G DK+    ++ E L+FE K+A +
Sbjct: 295 IDQATLSIPMRYYFT--KPEIVKTVRDYMTDVISLAGYDKSDVKRKVHELLKFEAKIALL 352

Query: 186 SLP 194
           ++P
Sbjct: 353 TVP 355


>UniRef50_Q9VAS4 Cluster: CG14529-PA; n=1; Drosophila
           melanogaster|Rep: CG14529-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 681

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 26/124 (20%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
 Frame = +3

Query: 57  SDKLVQAYYEYMVDIAI--LLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYN 230
           SD+    + +Y + + +  LLG  +  A +  +E ++ E++L+  +      R+   + +
Sbjct: 204 SDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRH 263

Query: 231 PMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQA 410
              ++ +   +   P L  + R +   +  + N     SVP Y+  ++ +L  TP  V A
Sbjct: 264 LTMLSNMSDAYG--PILN-VTRFVTSWLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVA 320

Query: 411 NYVM 422
           NY++
Sbjct: 321 NYML 324


>UniRef50_A6R8P3 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 639

 Score = 37.1 bits (82), Expect = 0.24
 Identities = 34/118 (28%), Positives = 54/118 (45%)
 Frame = +3

Query: 156 LQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNEL 335
           + FE KLA I +     R +T  Y+   +A+ Q   P++  LE I    AP I     ++
Sbjct: 181 VDFEKKLAEIHI---NARGSTVKYS---LADAQALLPQIS-LERIISAKAP-IGYKAEQI 232

Query: 336 TIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 509
            I   P+    L  LL  TP  +  +++ W+V     S + D + +    +  ALSGK
Sbjct: 233 VIYQ-PESFKQLSKLLADTPTPILNSFLKWKVIQNYASDIEDPIIKPYRRFHNALSGK 289


>UniRef50_UPI00015B5ABD Cluster: PREDICTED: similar to neutral
           endopeptidase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to neutral endopeptidase - Nasonia vitripennis
          Length = 485

 Score = 35.5 bits (78), Expect = 0.74
 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 16/155 (10%)
 Frame = +3

Query: 54  FSDKLVQAYYEYMVDIAILLG-ADKTKATEE-----LKESLQFEMKLANISLPLEKRRNA 215
           +  K    Y +Y+  +A+++    +T  +E+      K+   FE +L+ I L + +R + 
Sbjct: 151 YKAKSFYKYVDYIKSVAMVVANLSETNVSEQEVATGAKQVAAFEAELSKI-LEVSERLD- 208

Query: 216 TSLYNPMTIAELQQ--------KFPKVPWLEYINRLLAPHIT--VDVNELTIVSVPKYIT 365
              Y P+ + + Q         K   + W++ IN +  P  T  V + +   +S   Y  
Sbjct: 209 --FYRPILLGKFQNITDQLSRDKNNTLDWVKIINGMY-PSTTGLVTLQQSVDISTLSYFP 265

Query: 366 DLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLR 470
            L  LL  TP R   N++ WR     + + + +LR
Sbjct: 266 RLIQLLYNTPSRTVVNFIHWRFVHQFLPHTSGELR 300


>UniRef50_UPI000023D0A6 Cluster: hypothetical protein FG02748.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG02748.1 - Gibberella zeae PH-1
          Length = 715

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 30/128 (23%), Positives = 53/128 (41%)
 Frame = +3

Query: 126 TKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLA 305
           T ATE       F+MKL  I+        A+   + +    L++  P + +   I +L  
Sbjct: 229 TTATELAGSIYLFQMKLV-IAWAWSLENEAS---DDVPAGNLKKLAPNLDYEGVIKKLAP 284

Query: 306 PHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLA 485
            +    VN L     P Y T++  ++ +TP      Y +W++  +   Y+  DL      
Sbjct: 285 KNWKGTVNTL----YPSYFTNMSQIISQTPTETVQAYFVWKMISSVSPYIEHDLTNAYND 340

Query: 486 YITALSGK 509
           + + L GK
Sbjct: 341 FQSKLQGK 348


>UniRef50_Q8PIZ8 Cluster: Metallopeptidase; n=7;
           Xanthomonadaceae|Rep: Metallopeptidase - Xanthomonas
           axonopodis pv. citri
          Length = 671

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 29/131 (22%), Positives = 53/131 (40%)
 Frame = +3

Query: 66  LVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIA 245
           L+  Y  Y+  I  L G    K   +    LQ E  LA  +  ++   N  + Y P+   
Sbjct: 194 LMGRYRAYVKQILALTGTAADKLDADAASVLQIETALARSAQSVQGINNPFNNYAPIATK 253

Query: 246 ELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMW 425
           EL +++  +   +++    A  +  D   L  ++ P     L++++          Y+ W
Sbjct: 254 ELGKQYKNLRLADFLE---AQGVKDD---LVSMADPAMFKQLDSMIVSIKPDQWKAYLRW 307

Query: 426 RVAGASVSYLT 458
           RV  A   YL+
Sbjct: 308 RVGDAMAPYLS 318


>UniRef50_Q8EUQ0 Cluster: End peptidase; n=1; Mycoplasma
           penetrans|Rep: End peptidase - Mycoplasma penetrans
          Length = 635

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 33/152 (21%), Positives = 61/152 (40%)
 Frame = +3

Query: 60  DKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMT 239
           + L+Q +     DI      +K +    +KE+L F+  ++ I     +  + T  YNPM 
Sbjct: 161 EPLLQLWSNMTKDILGFFFENKEEVKTLIKETLLFDELISKIVKSRVEWADYTKNYNPMD 220

Query: 240 IAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYV 419
             E+++    V +     R +   +   + E  IV  P+++ +   L       +  ++ 
Sbjct: 221 FNEVEKLLKPVNF-----RNIVSTVYNSLPEKIIVFDPRFLKEFSKLFNDKTFNLFKSWA 275

Query: 420 MWRVAGASVSYLTDDLRRRQLAYITALSGKTE 515
           +      S  +L D LR     Y   LSG  E
Sbjct: 276 LVHFINESSEFLCDKLRILSGIYSRGLSGVKE 307


>UniRef50_Q7JMI4 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 807

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 28/134 (20%), Positives = 64/134 (47%), Gaps = 9/134 (6%)
 Frame = +3

Query: 96  DIAILLGADKTKATEELKES----LQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKF 263
           +++ +LG D T     +  +    L++++ +A  +   EK+      Y  + + ELQ+  
Sbjct: 326 ELSAVLGFDSTDEKVRMMIANMIYLEYQITMAGSTFYKEKKER----YTVVMLRELQEIA 381

Query: 264 PKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPK-----RVQANYVMWR 428
           P + W  +++RL+  +++     + + +  ++I  L A++EK  +      V  NYV W+
Sbjct: 382 PAINWHYFLSRLVGENLS-HSEPIALKTGTQWIPILSAIVEKLKQSRSGVAVLKNYVKWK 440

Query: 429 VAGASVSYLTDDLR 470
                ++Y +   R
Sbjct: 441 TIMFHLAYASPKCR 454


>UniRef50_Q9VAS1 Cluster: CG14523-PA; n=3; Sophophora|Rep:
           CG14523-PA - Drosophila melanogaster (Fruit fly)
          Length = 671

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
 Frame = +3

Query: 111 LGADKTKATEELKESLQFEMKLANISLPLEKRRNATS-LYNPMTIAELQQKFPKVPWLEY 287
           LG D   A    +E  +FE K+A I +  ++R    S LY P     +          ++
Sbjct: 239 LGVDPKVAVTTAREITEFEQKIAAIMV--DRRVGVMSKLYTPSDADYVDVS----KLTQF 292

Query: 288 INRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYV 419
           +  +L   +    NE     VP Y+  ++ L+ +TP  V ANYV
Sbjct: 293 VETVLDRELLA--NESLYQHVPDYLMKIDELVTETPPHVLANYV 334


>UniRef50_Q25051 Cluster: Zinc metallopeptidase precursor; n=3;
           Haemonchus contortus|Rep: Zinc metallopeptidase
           precursor - Haemonchus contortus (Barber pole worm)
          Length = 793

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
 Frame = +3

Query: 147 KESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLL--APHITV 320
           KE + FE ++A  S P  + R     YN   I  L    P + W  Y++ LL   P +  
Sbjct: 273 KEIVNFEREMAMASWPDTEMREYAQQYNEFDIGILTADIPGIEWKPYLDELLLSVPEVEK 332

Query: 321 DV-NELTIVSVPKY 359
            + N+  I+  P Y
Sbjct: 333 ALENKKIILPQPSY 346


>UniRef50_A3VNT9 Cluster: Peptidase M13 family protein; n=1;
           Parvularcula bermudensis HTCC2503|Rep: Peptidase M13
           family protein - Parvularcula bermudensis HTCC2503
          Length = 721

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
 Frame = +3

Query: 6   LDQASLGLSRE--YLNRGFSDKLVQAYYEYMVDIAIL---------LGADKTKA--TEEL 146
           L Q+ LGL  +  Y+   F+++  +AY +++V +            LG   T+    +  
Sbjct: 208 LTQSGLGLPNKDYYVKDEFAEQR-EAYQDFLVQMVATADRALAENGLGVTVTEGDVADRA 266

Query: 147 KESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPW 278
                 E KLA+      KRRNA   YN  T+AEL    P  PW
Sbjct: 267 AAVYALEEKLADAHWDPAKRRNADLTYNLYTLAELGDYAPGFPW 310


>UniRef50_Q22SS7 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1107

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
 Frame = +3

Query: 39  YLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNAT 218
           YL++ F +     Y+ Y +     +  +    T+E K+ L  ++ L+ +S+P     N+ 
Sbjct: 359 YLSKIFWNSKYYCYHTYFLYNHYFIHKNLPNITDEEKQKLTNQILLSVLSIPSSSLENSQ 418

Query: 219 SLYNPMTIAELQQKFPK-VPWL-EYINRLLAPHITVDVNE 332
           +  + M IA+LQ+   K +P   E IN +L  ++    NE
Sbjct: 419 NEDSRMKIAQLQKGTSKLIPRREEIINMVLRMNLNEFANE 458


>UniRef50_Q7UM68 Cluster: Probable zinc metalloproteinase; n=1;
           Pirellula sp.|Rep: Probable zinc metalloproteinase -
           Rhodopirellula baltica
          Length = 759

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 40/175 (22%), Positives = 68/175 (38%), Gaps = 3/175 (1%)
 Frame = +3

Query: 6   LDQASLGL-SREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESL-QFEMKLA 179
           L Q+ L L  R+Y       + V A     V I  +L A   ++ +EL E +   E +LA
Sbjct: 257 LSQSGLTLPDRDYYLED-DPQYVSAREALQVYIKDMLNALSVESAKELAEQVVAIETELA 315

Query: 180 NISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKY 359
                  + R+    YN +T+ E+          ++    +   I +   +  +V  P Y
Sbjct: 316 KNQWTKTENRDPEKTYNKLTLGEVDATIE-----DFNVPAMTKAIGLADQDAFVVRQPSY 370

Query: 360 ITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAY-ITALSGKTERE 521
           +  L  +           Y  +    A  S LT+DL RR   +    +SG  E++
Sbjct: 371 MESLSDIFANHDLAAWKAYFQFHSIDAYASVLTEDLERRHFEFHDKTISGIDEQQ 425


>UniRef50_Q4JY76 Cluster: Putative endopeptidase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           endopeptidase - Corynebacterium jeikeium (strain K411)
          Length = 700

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 34/129 (26%), Positives = 53/129 (41%), Gaps = 10/129 (7%)
 Frame = +3

Query: 162 FEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEY--INRLLAPHITVDVNEL 335
           FE +LA         R+A   YNP  + +L   FP   WL    ++   A   T+     
Sbjct: 215 FETELARGHWDNVASRDAEKTYNPTKVEDLPTGFPFREWLAATGVDTQSAGGSTI----- 269

Query: 336 TIVSVPKYITDLEALLEKTPKRVQAN-------YVMWRVAGASVSYLTDDLRRRQLA-YI 491
            +V  P Y+  + A+     +  Q +       +  WRV  +S +YL  ++  R    Y 
Sbjct: 270 -VVCQPSYLEHVAAMATDAGENPQVSGLDEWKLWAYWRVILSSAAYLPTEVNLRNWEFYG 328

Query: 492 TALSGKTER 518
             LSG TE+
Sbjct: 329 RTLSGATEQ 337


>UniRef50_Q2IQ33 Cluster: Endothelin-converting enzyme 1 precursor;
           n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep:
           Endothelin-converting enzyme 1 precursor -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 686

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 30/145 (20%), Positives = 59/145 (40%), Gaps = 3/145 (2%)
 Frame = +3

Query: 6   LDQASLGL-SREYL--NRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKL 176
           ++Q  L L  REY   + G + ++ +A+  ++  +  L G    +A        +FE  L
Sbjct: 178 VNQGGLSLPDREYYLSDAGKNPEIRRAWAAHLRRMLGLAGLPPAQAEAGAAAVEKFETGL 237

Query: 177 ANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPK 356
           A       + R+   +YN +  A L++  P  PW  +   L  P +     +   V+ P 
Sbjct: 238 ARTHWTRAELRDPARIYNRVDRAGLERLAPDFPWARFFADLGQPGL-----DAVSVTTPA 292

Query: 357 YITDLEALLEKTPKRVQANYVMWRV 431
           ++ ++       P      Y+ W +
Sbjct: 293 FVAEVGKQFASAPLDAWKAYLRWHL 317


>UniRef50_Q9VAS2 Cluster: CG14528-PA; n=2; Drosophila
           melanogaster|Rep: CG14528-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 682

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 23/114 (20%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
 Frame = +3

Query: 93  VDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPK- 269
           +D+    G   + A    ++  + E   ++        + + SLY   T+A+LQ+K+   
Sbjct: 221 MDLQQYFGLSSSVAKHTAEQLTELERTFSSGGSGAATLQESLSLY---TVADLQEKYSDH 277

Query: 270 VPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRV 431
           + + E++  +L      ++ +   +   +Y+      +  TP   QANYV+W++
Sbjct: 278 LNFTEFLGLILGEE---NIPKSLYIYDEEYLDKALLTMRSTPLATQANYVLWKL 328


>UniRef50_UPI00015B6074 Cluster: PREDICTED: similar to
           Endothelin-converting enzyme 1; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to
           Endothelin-converting enzyme 1 - Nasonia vitripennis
          Length = 746

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = +3

Query: 270 VPWLEYINRLL-APHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASV 446
           + WL  +N LL   ++ +D ++  ++    Y T L  LL++T       Y+ ++      
Sbjct: 320 IDWLRLLNSLLKTANVRIDKHDYIVLKKLDYFTKLAELLDRTSPVTVEKYIHFKFLTQIS 379

Query: 447 SYLTDDLRR 473
            YL+  L R
Sbjct: 380 KYLSPSLAR 388


>UniRef50_Q9VCU1 Cluster: CG4721-PA; n=3; Sophophora|Rep: CG4721-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 686

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
 Frame = +3

Query: 138 EELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPK-VPWLEYINRLLAPHI 314
           E   + +Q E +LA   LP              T AE++  +   V    Y+  +   ++
Sbjct: 241 EVASQVVQIEQQLAK-GLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFNDNL 299

Query: 315 TVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGA 440
            +D+ E    +   Y+++L  ++ +TPK   ANY MW+   A
Sbjct: 300 YMDLYE----TPEDYMSNLVDVIRETPKLQLANYTMWKALEA 337


>UniRef50_Q5KLS5 Cluster: Endothelin-converting enzyme 1, putative;
           n=2; Filobasidiella neoformans|Rep:
           Endothelin-converting enzyme 1, putative - Cryptococcus
           neoformans (Filobasidiella neoformans)
          Length = 914

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 25/93 (26%), Positives = 40/93 (43%)
 Frame = +3

Query: 156 LQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNEL 335
           L+FE  L       E   N    YNP + + +    P +    Y++   AP       E 
Sbjct: 444 LKFEKDLVKAGADPEYLFNPHYAYNPYSTSAVSDALPFLDIPTYLSAF-APRT---FPEN 499

Query: 336 TIVSVPKYITDLEALLEKTPKRVQANYVMWRVA 434
             V+ P Y+  +  L+E+TP  V + Y + R+A
Sbjct: 500 ITVTYPPYLKAVTRLVEQTPDEVLSGYFVTRLA 532


>UniRef50_Q1H499 Cluster: Putative uncharacterized protein; n=1;
           Methylobacillus flagellatus KT|Rep: Putative
           uncharacterized protein - Methylobacillus flagellatus
           (strain KT / ATCC 51484 / DSM 6875)
          Length = 176

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
 Frame = +3

Query: 33  REYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISL--PLEKR 206
           R    RG+S +L+   ++   DI + L   +   +  LK   + +M+  N S    LEK 
Sbjct: 40  RSMEQRGYSKRLMSVTHKIAYDIYLTLHNIEQLRSNPLKSETR-QMRDFNRSKLGRLEKA 98

Query: 207 RNATSLYNPMTIAELQQKFPKVPWLEYINRLLAP 308
            +A  L+N  TI  ++Q       +E  N LLAP
Sbjct: 99  LHAIPLHNLGTITAVEQVMIIFSQIEAANNLLAP 132


>UniRef50_Q9VTV4 Cluster: CG5626-PA; n=2; Sophophora|Rep: CG5626-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 383

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 16/45 (35%), Positives = 27/45 (60%)
 Frame = +1

Query: 286 TSTDCLRHTLRSMLMNLPLSAYPNTSPILRLYWRRLLNVYKLTTS 420
           TS DC+   L+  + NLP+  +  TSPI  +  +R+ ++ +L TS
Sbjct: 182 TSADCIWALLKEKVGNLPVPDHIKTSPIYPIAEKRMEDLKELITS 226


>UniRef50_Q7QZ72 Cluster: GLP_22_12403_9005; n=2; Giardia
            intestinalis|Rep: GLP_22_12403_9005 - Giardia lamblia
            ATCC 50803
          Length = 1132

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
 Frame = +1

Query: 319  SMLMNLPLSAYPNTSPIL-RLYWRRLLN 399
            S+LM++PL+AYP   P+L R+ WR   N
Sbjct: 1072 SLLMSIPLAAYPQNLPVLIRVGWRASAN 1099


>UniRef50_Q6G472 Cluster: Hemin degrading protein; n=3;
           Bartonella|Rep: Hemin degrading protein - Bartonella
           henselae (Rochalimaea henselae)
          Length = 347

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
 Frame = +1

Query: 250 FNRNSPRFRGWNTSTDCLRHTLRSMLMNLPLSAYPNTSPILRL-------YWRRLLNVYK 408
           +++++     WN   D L H  +S ++++P  A PN   I+ L        WR++ +V++
Sbjct: 138 YSKDTTNMAEWNKLVDKLLHEDQSPVLDIPPKAIPNKRDIVELNVEEFRDRWRKMTDVHQ 197

Query: 409 LTTSCGEL 432
           L     EL
Sbjct: 198 LHGIISEL 205


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 510,755,894
Number of Sequences: 1657284
Number of extensions: 9745748
Number of successful extensions: 25168
Number of sequences better than 10.0: 120
Number of HSP's better than 10.0 without gapping: 24445
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25094
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 32619212418
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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