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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ovS302H07f
         (521 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate...   249   3e-65
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch...   245   4e-64
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ...   223   2e-57
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ...   223   3e-57
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ...   198   5e-50
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ...   181   8e-45
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial...   181   1e-44
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi...   180   2e-44
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3...    95   1e-18
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase...    92   6e-18
UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma j...    83   4e-15
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase...    69   5e-11
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro...    69   5e-11
UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1; ...    67   2e-10
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ...    62   7e-09
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B...    52   1e-05
UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza sa...    44   0.002
UniRef50_Q5E609 Cluster: Putative uncharacterized protein; n=1; ...    35   0.98 
UniRef50_Q54LD3 Cluster: Putative uncharacterized protein; n=1; ...    34   1.7  
UniRef50_Q142V0 Cluster: Putative uncharacterized protein; n=1; ...    33   4.0  
UniRef50_UPI0000498AD5 Cluster: hypothetical membrane-spanning p...    33   5.2  
UniRef50_Q9C9W7 Cluster: Putative uncharacterized protein T23K23...    33   5.2  
UniRef50_Q0WVR7 Cluster: TRNA synthase-like protein; n=7; Eukary...    33   5.2  
UniRef50_A5BB87 Cluster: Putative uncharacterized protein; n=1; ...    33   5.2  
UniRef50_Q0U2D2 Cluster: Predicted protein; n=1; Phaeosphaeria n...    33   5.2  
UniRef50_Q18BL4 Cluster: Putative exported protein precursor; n=...    32   6.9  
UniRef50_Q0SU98 Cluster: DNA/RNA helicase, SNF2; n=2; Clostridiu...    32   6.9  
UniRef50_A0C382 Cluster: Chromosome undetermined scaffold_146, w...    32   6.9  
UniRef50_UPI0000D55581 Cluster: PREDICTED: similar to CG12404-PA...    32   9.2  
UniRef50_Q7QSR2 Cluster: GLP_714_26114_29632; n=1; Giardia lambl...    32   9.2  
UniRef50_A5E1L5 Cluster: Putative uncharacterized protein; n=1; ...    32   9.2  

>UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate
           dehydrogenase 1 (NADP+), soluble; n=2; Danio rerio|Rep:
           PREDICTED: similar to Isocitrate dehydrogenase 1
           (NADP+), soluble - Danio rerio
          Length = 206

 Score =  249 bits (610), Expect = 3e-65
 Identities = 112/140 (80%), Positives = 129/140 (92%), Gaps = 1/140 (0%)
 Frame = +2

Query: 68  YNMS-KIKAGPVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTI 244
           + MS KIKAG VV++ GDEMTR+IW+LIKEKLI P+L+++LH YDLGMENRD TDD+VT+
Sbjct: 6   FKMSQKIKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTV 65

Query: 245 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 424
           + AEA+++YNVGIKCATITPDEKRVEEFKLK+MW+SPNGTIRNILGGTVFREAIICKNIP
Sbjct: 66  EAAEAVRRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIP 125

Query: 425 RLVTGWDKPIIIGRHAHADQ 484
           RLV GW KPIIIGRHAH DQ
Sbjct: 126 RLVPGWIKPIIIGRHAHGDQ 145


>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
           mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
           decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
           cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
           mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
           decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
           sapiens (Human)
          Length = 452

 Score =  245 bits (600), Expect = 4e-64
 Identities = 116/155 (74%), Positives = 128/155 (82%), Gaps = 1/155 (0%)
 Frame = +2

Query: 59  RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQ 235
           R  Y   +IK A PVV++ GDEMTRIIW  IKEKLI+P +DI+L  +DLG+ NRD+TDDQ
Sbjct: 36  RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95

Query: 236 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 415
           VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96  VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155

Query: 416 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAG 520
           NIPRLV GW KPI IGRHAH DQYKATDFV   AG
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAG 190


>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
           n=6; core eudicotyledons|Rep: Isocitrate
           dehydrogenase-like protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 485

 Score =  223 bits (545), Expect = 2e-57
 Identities = 98/142 (69%), Positives = 119/142 (83%)
 Frame = +2

Query: 95  PVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYN 274
           P+V++ GDEMTR+IW +IKEKLI+P+LD+++  +DLG+ NRD TDD+VT++ AEA  KYN
Sbjct: 81  PIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTVESAEAALKYN 140

Query: 275 VGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPI 454
           V IKCATITPDE RV+EF LK MW+SPNGTIRNIL GTVFRE I+C NIPRLV GW+KPI
Sbjct: 141 VAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIPRLVPGWEKPI 200

Query: 455 IIGRHAHADQYKATDFVVPGAG 520
            IGRHA  DQY+ATD V+ G G
Sbjct: 201 CIGRHAFGDQYRATDTVIKGPG 222


>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
           organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 410

 Score =  223 bits (544), Expect = 3e-57
 Identities = 101/148 (68%), Positives = 122/148 (82%), Gaps = 1/148 (0%)
 Frame = +2

Query: 80  KIK-AGPVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAE 256
           KIK A P+V++ GDEMTR+IW  IK+KLI PF+++++  +DLG+ +RD TDD+VTI+ AE
Sbjct: 5   KIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGLPHRDATDDKVTIESAE 64

Query: 257 AIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVT 436
           A KKYNV IKCATITPDE RV EF LK+MW+SPNGTIRNIL GTVFRE IICKN+P+LV 
Sbjct: 65  ATKKYNVAIKCATITPDEGRVTEFGLKQMWRSPNGTIRNILNGTVFREPIICKNVPKLVP 124

Query: 437 GWDKPIIIGRHAHADQYKATDFVVPGAG 520
           GW KPI IGRHA  DQY+ATD V+ G G
Sbjct: 125 GWTKPICIGRHAFGDQYRATDAVIKGPG 152


>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
           Eukaryota|Rep: Putative uncharacterized protein - Oryza
           sativa subsp. indica (Rice)
          Length = 475

 Score =  198 bits (484), Expect = 5e-50
 Identities = 99/154 (64%), Positives = 110/154 (71%), Gaps = 18/154 (11%)
 Frame = +2

Query: 113 GDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCA 292
           GDEMTR+IW  IK+KLI PFLD+++  YDLG+ NRD T D+VTI+ AEA  KYNV IKCA
Sbjct: 42  GDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGLPNRDATGDKVTIESAEATLKYNVAIKCA 101

Query: 293 TITP------------------DEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKN 418
           TITP                  DE RV+EF L  MWKSPNGTIRNIL GTVFRE IICKN
Sbjct: 102 TITPVLDTQFKFDFGRTIHEPTDEGRVKEFNLSAMWKSPNGTIRNILNGTVFREPIICKN 161

Query: 419 IPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAG 520
           IPRLV GW KPI IGRHA  DQY+ATD V+ G G
Sbjct: 162 IPRLVPGWIKPICIGRHAFGDQYRATDTVIKGPG 195


>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 417

 Score =  181 bits (441), Expect = 8e-45
 Identities = 83/150 (55%), Positives = 109/150 (72%), Gaps = 1/150 (0%)
 Frame = +2

Query: 74  MSKIK-AGPVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDC 250
           M KI+   P+V++ GDEMTRI+W +IK++L++PF+D+    YDLG+  R++TDDQVTID 
Sbjct: 16  MEKIQMTTPLVEMDGDEMTRILWKMIKDELLLPFIDLNTEYYDLGLNYRNETDDQVTIDA 75

Query: 251 AEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRL 430
           AEA KKY V +KCATITP+  R++E+ LKKM+KSPNGTIR IL GTVFR  I+ K I   
Sbjct: 76  AEATKKYGVAVKCATITPNHARMDEYDLKKMYKSPNGTIRAILDGTVFRAPIVVKGIEPC 135

Query: 431 VTGWDKPIIIGRHAHADQYKATDFVVPGAG 520
           V  W KPI + RHA+ D YK T+  +   G
Sbjct: 136 VRNWKKPITLARHAYGDIYKNTEMYIDKPG 165


>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
           n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
           mitochondrial - Aspergillus terreus (strain NIH 2624)
          Length = 466

 Score =  181 bits (440), Expect = 1e-44
 Identities = 82/106 (77%), Positives = 91/106 (85%)
 Frame = +2

Query: 203 GMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILG 382
           G+E RD+TDD+VT++ AEAIKKY VG+KCATITPDE RVEEFKLKKMW SPNGTIRNILG
Sbjct: 101 GIEYRDQTDDKVTVEAAEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILG 160

Query: 383 GTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAG 520
           GTVFRE I+   IPRLV GW KPIIIGRHA  DQY+ATD V+PG G
Sbjct: 161 GTVFREPIVIPAIPRLVPGWTKPIIIGRHAFGDQYRATDRVIPGPG 206


>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
           kluyveri DSM 555
          Length = 401

 Score =  180 bits (437), Expect = 2e-44
 Identities = 82/148 (55%), Positives = 110/148 (74%), Gaps = 1/148 (0%)
 Frame = +2

Query: 80  KIKAG-PVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAE 256
           KIK   P+V++ GDEMTRIIW +IKE L+ P++D++   YDLG+  R++T+D++TI+ A 
Sbjct: 4   KIKMNVPLVEMDGDEMTRIIWKMIKELLLEPYIDLKTEYYDLGLVKRNETNDEITIEAAN 63

Query: 257 AIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVT 436
           AIKKY VG+KCATITP+ KRV+E+ LK MWKSPNGTIR IL GTVFR  II  +I  L+ 
Sbjct: 64  AIKKYGVGVKCATITPNAKRVKEYNLKSMWKSPNGTIRAILDGTVFRTPIIVNSIRPLMR 123

Query: 437 GWDKPIIIGRHAHADQYKATDFVVPGAG 520
            W+KPI + RHA+ D Y+  ++ V   G
Sbjct: 124 TWEKPITVARHAYGDVYRDVEYKVEEPG 151


>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
           Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
           Ostreococcus tauri
          Length = 429

 Score = 94.7 bits (225), Expect = 1e-18
 Identities = 54/141 (38%), Positives = 80/141 (56%), Gaps = 2/141 (1%)
 Frame = +2

Query: 77  SKIKAGPVVDILGDEMTRIIWDLIKEKLIIPFLDIE-LHVYDLGMENRDKTDDQVTIDCA 253
           SKI A P+V + G+EMT  + DLI+ + I P +D+     +DL  +NRD T+D+V  D  
Sbjct: 24  SKITAAPMVYVRGEEMTAYVMDLIRSRWIEPRVDVGGWETFDLRAKNRDDTEDRVLRDVI 83

Query: 254 EAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGG-TVFREAIICKNIPRL 430
           EA K+     K  T+TP   +V+   L+K W SPNG +R    G T+ R+ I   +I  +
Sbjct: 84  EAGKRIKAIFKEPTVTPTADQVKRLGLRKSWGSPNGAMRRGWNGITISRDTI---HIDGV 140

Query: 431 VTGWDKPIIIGRHAHADQYKA 493
             G+ KP++  RHA   +Y A
Sbjct: 141 ELGYKKPVLFERHAVGGEYSA 161


>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
           protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
           isocitrate dehydrogenase protein - Rhizobium etli
           (strain CFN 42 / ATCC 51251)
          Length = 437

 Score = 92.3 bits (219), Expect = 6e-18
 Identities = 44/135 (32%), Positives = 81/135 (60%)
 Frame = -2

Query: 502 KVSCFVLISMSMTSNDDGFVPPCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKF 323
           +V C VL++ S+T++DD   P   ++R + A++ L E+   +N++D  +RA PHFL+ +F
Sbjct: 279 EVGCAVLVAESVTADDDRLRPAGNEARNVAADDRLAEDDAAENVSDRAVRALPHFLEIEF 338

Query: 322 FNSLLIRSYGRTFDAHIVFLYGLSTINCNLIISLITIFHSQVVDM*FNVQERNNQLFFDK 143
            ++  IR      D   VFL G+  ++ +L++  + IF  +VV +   V+ R +QL  D+
Sbjct: 339 LDAGFIRRDRCALDTDAVFLDGVGGVDRHLVVGGVAIFDREVVIVDIEVEIRMDQLILDE 398

Query: 142 IPDYSGHFITKDVNN 98
           +PD + HFI  ++ +
Sbjct: 399 LPDDACHFIAVEIGD 413


>UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC09598 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 129

 Score = 83.0 bits (196), Expect = 4e-15
 Identities = 51/91 (56%), Positives = 55/91 (60%)
 Frame = -3

Query: 405 IASLKTVPPRILRMVPLGLFHIXXXXXXXXXXXSGVMVAHLMPTLYFFMASAQSIVT*SS 226
           + S KTVPPRILR+VP G  HI           SGVMVAHL+PTLYF +ASA SIVT S 
Sbjct: 1   MGSRKTVPPRILRIVPFGDSHIFFKLNSLTRCSSGVMVAHLIPTLYFLIASAPSIVTWSL 60

Query: 225 VLSRFSIPKS*TCNSMSKKGIISFSLIRSQI 133
           V SR   PKS    S S  G IS   IRS I
Sbjct: 61  VRSRLGRPKSKYLQSTSINGNISCCFIRSII 91


>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
           protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
           isocitrate dehydrogenase protein - Sagittula stellata
           E-37
          Length = 459

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 33/131 (25%), Positives = 71/131 (54%)
 Frame = -2

Query: 487 VLISMSMTSNDDGFVPPCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNSLL 308
           VL++  + ++ DG  P  +++R++ A++ L E+   +++ D  +   PH L+ +F ++LL
Sbjct: 315 VLVAEGVPAHHDGRGPARHEARHVAADDRLAEDDAAQDVADRAVGRLPHLLETEFLDTLL 374

Query: 307 IRSYGRTFDAHIVFLYGLSTINCNLIISLITIFHSQVVDM*FNVQERNNQLFFDKIPDYS 128
           +R   R FD     L     ++ +L+   + +   ++V     V+ R +QLF D+ P  +
Sbjct: 375 VRGDRRAFDRDANLLRLFGGVDGDLVPGPVPLLDPEIVVKQVQVEVRQDQLFLDESPHDA 434

Query: 127 GHFITKDVNNR 95
           GH +   +++R
Sbjct: 435 GHLVAVHLHDR 445


>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
           Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
           Marinobacter sp. ELB17
          Length = 582

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 45/128 (35%), Positives = 73/128 (57%), Gaps = 12/128 (9%)
 Frame = +2

Query: 74  MSKIKA-GPVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDC 250
           ++KI+   P+V + GDEM ++ ++ I +K +   L IEL   DL  E+R  T+ QV  + 
Sbjct: 2   VNKIQVESPLVILHGDEMAQVAFEEILKKFVTTRLAIELIEIDLSAEHRFLTNGQVIFEA 61

Query: 251 AEAIKKYNVGIKCATITPDEKRVE-------EFKLKKM----WKSPNGTIRNILGGTVFR 397
            EA+KKY VG+K A +T + ++++       E    ++     KSPNG IR  +GG + R
Sbjct: 62  IEALKKYGVGVKNAGMTVNREQLDAMLEKHPELSQSRLDPLATKSPNGAIRKGIGGNITR 121

Query: 398 EAIICKNI 421
           E I  +N+
Sbjct: 122 EDIQFQNL 129


>UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 141

 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 49/103 (47%), Positives = 59/103 (57%)
 Frame = -3

Query: 375 ILRMVPLGLFHIXXXXXXXXXXXSGVMVAHLMPTLYFFMASAQSIVT*SSVLSRFSIPKS 196
           +LR+VPLG  HI           S V+VAHL+PTL   +A A S VT S V SRFSI +S
Sbjct: 1   MLRIVPLGEGHIFLSLNSLTRASSAVIVAHLIPTLCSRIAQAASKVTQSLVASRFSIERS 60

Query: 195 *TCNSMSKKGIISFSLIRSQIILVISSPRMSTTGPAFILDILY 67
               S    G +S SLI  Q+I VISSP  ST G  F+  IL+
Sbjct: 61  QYLISAEINGNMSLSLIIFQMIRVISSPSKSTIG--FLTLILF 101


>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. indica (Rice)
          Length = 371

 Score = 62.1 bits (144), Expect = 7e-09
 Identities = 24/32 (75%), Positives = 30/32 (93%)
 Frame = +2

Query: 341 MWKSPNGTIRNILGGTVFREAIICKNIPRLVT 436
           MW+SPNGTIRNIL GTVFRE I+CKN+PR+++
Sbjct: 1   MWRSPNGTIRNILNGTVFREPILCKNVPRILS 32


>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
           Bacteria|Rep: 3-isopropylmalate dehydrogenase -
           Symbiobacterium thermophilum
          Length = 357

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
 Frame = +2

Query: 98  VVDILGDEMTRIIWDLIKEKLIIPFLDIELHV--YDLGMENRDKTDDQVTIDCAEAIKKY 271
           +V + GD+  + + +     L    + + LH+  YDL +ENR  T ++V  + A A++++
Sbjct: 7   IVVLEGDQTGQELLEEAVRLLSPDVIGLPLHLVRYDLSLENRRATSNRVVYEAAAAMREH 66

Query: 272 NVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVT--GWD 445
             G+K ATITP E R +         SPN  +R  + GTV       + +P + T  G  
Sbjct: 67  GYGLKAATITP-EGRGDV-------GSPNAILRREIDGTVILRT--GRPLPGVETIGGIT 116

Query: 446 KPIIIGRHAHADQYKATDF 502
            PI + R A  D Y+A ++
Sbjct: 117 APIAVVRMATEDAYEAKEW 135


>UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza
           sativa|Rep: Isocitrate dehydrogenase - Oryza sativa
           (Rice)
          Length = 61

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/26 (65%), Positives = 22/26 (84%)
 Frame = +2

Query: 113 GDEMTRIIWDLIKEKLIIPFLDIELH 190
           GDEMTRI W  IK+KLI PFLD++++
Sbjct: 36  GDEMTRIFWQSIKDKLIFPFLDLDIN 61


>UniRef50_Q5E609 Cluster: Putative uncharacterized protein; n=1;
           Vibrio fischeri ES114|Rep: Putative uncharacterized
           protein - Vibrio fischeri (strain ATCC 700601 / ES114)
          Length = 326

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
 Frame = +2

Query: 194 YDLGMENRDKTDDQVTIDCA--EAIKKYNVGIKCATITPDEKRVEE 325
           +  G +  DK +    +DC+      KYN+ +KCAT + DEK   E
Sbjct: 86  FSQGFKYEDKVNPPKDVDCSVYHDYAKYNIEVKCATFSDDEKLKSE 131


>UniRef50_Q54LD3 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1137

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
 Frame = -2

Query: 391  NSTTKNITDGPIRAFPHFLQFKFFNSLLIRSYGRTFDAHIVFLY-GLSTINCNLI--ISL 221
            N+ T      P+R FPH        S+LI+ Y    D + +F +  +S+I   +I  + L
Sbjct: 933  NTNTFIAATSPLRNFPHLFNQIQLTSILIKKYQNQNDIYPIFNWNNISSIGNEVIKTLDL 992

Query: 220  ITIFHSQVVDM*FNVQERNNQLFFDKIPDYS 128
               F S++VD  F +Q  N  +   +I + S
Sbjct: 993  KQAFESKLVDY-FVLQSINKDISSQRIKNSS 1022


>UniRef50_Q142V0 Cluster: Putative uncharacterized protein; n=1;
           Burkholderia xenovorans LB400|Rep: Putative
           uncharacterized protein - Burkholderia xenovorans
           (strain LB400)
          Length = 274

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 27/102 (26%), Positives = 44/102 (43%)
 Frame = +2

Query: 92  GPVVDILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKY 271
           G  +   GD M         E+LI P LD    +       ++ T D + +D   A   Y
Sbjct: 28  GSALSFRGDRMDAKREASFFERLIEPMLDQLRRI--ASTTRKEYTVDDLKVDAFIAANDY 85

Query: 272 NVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFR 397
              +    + P++++++E  LKK+WK+  G   N    T FR
Sbjct: 86  QQELG-VELEPEDEKLQEAVLKKLWKA-FGKFANRTLRTAFR 125


>UniRef50_UPI0000498AD5 Cluster: hypothetical membrane-spanning
           protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           hypothetical membrane-spanning protein - Entamoeba
           histolytica HM-1:IMSS
          Length = 453

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 21/76 (27%), Positives = 37/76 (48%)
 Frame = -2

Query: 439 PCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNSLLIRSYGRTFDAHIVFLY 260
           P Y  R +L    +  ++ +  +   P+R   +F Q  F N  ++  Y R +D   + +Y
Sbjct: 75  PFYLERSVLIGLLISWDTFSSFLLFTPLRIISYFYQLIFLNEKVVIHYKRIYD---ILMY 131

Query: 259 GLSTINCNLIISLITI 212
            LST+ C +II  + I
Sbjct: 132 -LSTLFCVIIIYQVDI 146


>UniRef50_Q9C9W7 Cluster: Putative uncharacterized protein
           T23K23.12; n=1; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein T23K23.12 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 314

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
 Frame = -2

Query: 145 KIPDYSGHFITKDVNNR--SSLYFRHIVSVTGVTTT 44
           K+PDY G +  + V  R  +SL+  H+VSVT  TTT
Sbjct: 49  KLPDYLGEYTNEMVAFRCLASLFDSHVVSVTTTTTT 84


>UniRef50_Q0WVR7 Cluster: TRNA synthase-like protein; n=7;
           Eukaryota|Rep: TRNA synthase-like protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 540

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 27/101 (26%), Positives = 43/101 (42%)
 Frame = +2

Query: 149 KEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEF 328
           K+K++         V  +GMEN D+ DD++        K+     +   +   EK+VE+F
Sbjct: 222 KKKVVAALGGKRSEVKRIGMENCDEDDDKLVFFDEVKEKEEKKKSEDDVVVVTEKKVEQF 281

Query: 329 KLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKP 451
             K + KSPN   + +  G    E  +      L   WD P
Sbjct: 282 -FKGLTKSPNE--KGMASGGGDGEPFLVTRNGELPPRWDGP 319


>UniRef50_A5BB87 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 745

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 13/35 (37%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
 Frame = +2

Query: 176 DIELHVYDLGMENRDKTDDQVTIDC-AEAIKKYNV 277
           D+E++VYD+ +++RD+ D   T+ C  E I++Y +
Sbjct: 27  DVEVYVYDMIVKSRDRGDHLATLGCFFEMIRRYKL 61


>UniRef50_Q0U2D2 Cluster: Predicted protein; n=1; Phaeosphaeria
           nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
           (Septoria nodorum)
          Length = 160

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 22/73 (30%), Positives = 35/73 (47%)
 Frame = -2

Query: 382 TKNITDGPIRAFPHFLQFKFFNSLLIRSYGRTFDAHIVFLYGLSTINCNLIISLITIFHS 203
           T  +T     A P+F+ F+  +SLL+   GR  D H + ++ LS    N+ I  +    +
Sbjct: 25  TAIVTTASTAARPNFVSFRHTHSLLVDELGRFNDVHAIQVFSLS---WNVSIRFLIGDPN 81

Query: 202 QVVDM*FNVQERN 164
           Q+  M F   E N
Sbjct: 82  QLPPMTFGPDELN 94


>UniRef50_Q18BL4 Cluster: Putative exported protein precursor; n=2;
           Clostridium difficile|Rep: Putative exported protein
           precursor - Clostridium difficile (strain 630)
          Length = 356

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 21/67 (31%), Positives = 34/67 (50%)
 Frame = +2

Query: 143 LIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 322
           L +EK+ I  LDI +   ++ ++     D +VT        KYNV +K  T+    +R  
Sbjct: 48  LYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVKGERKY 107

Query: 323 EFKLKKM 343
           E K+KK+
Sbjct: 108 ENKIKKI 114


>UniRef50_Q0SU98 Cluster: DNA/RNA helicase, SNF2; n=2; Clostridium
           perfringens|Rep: DNA/RNA helicase, SNF2 - Clostridium
           perfringens (strain SM101 / Type A)
          Length = 1069

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 27/143 (18%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
 Frame = -2

Query: 487 VLISMSMTSNDDGFVPPCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLQF-KFFNSL 311
           V +++++    +GF+   +K   I+ NNS       +N+     R   +++   K F   
Sbjct: 265 VPVALTLKEGKEGFILSHHKKFPIILNNSGDVMFFDRNLYLPRKRQLEYYIPIHKLFLKN 324

Query: 310 LIRSYGRTFDAHIVFLYGLSTINCNLIISL-ITIFHSQVVDM*FNVQERNNQLFFDKIPD 134
              +Y ++ +     L  L  I+ N+++   I +F  +++   FN+ +   +++ +   D
Sbjct: 325 NTITYKKSLENLRSLLEELKNISKNIVLDENIRVFKEKLMKTTFNLYKNKEKVYCNVKID 384

Query: 133 YSGHFITKDVNNRSSLYFRHIVS 65
           Y G+ I    + + + + R + S
Sbjct: 385 YCGYIIDLIRDEKDNSFLRDLKS 407


>UniRef50_A0C382 Cluster: Chromosome undetermined scaffold_146,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_146,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 198

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 14/26 (53%), Positives = 17/26 (65%)
 Frame = -2

Query: 409 NNSLPENSTTKNITDGPIRAFPHFLQ 332
           NNS P N +TKN     I++FP FLQ
Sbjct: 43  NNSTPHNLSTKNKISNIIQSFPQFLQ 68


>UniRef50_UPI0000D55581 Cluster: PREDICTED: similar to CG12404-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG12404-PA - Tribolium castaneum
          Length = 251

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 16/48 (33%), Positives = 29/48 (60%)
 Frame = -2

Query: 280 AHIVFLYGLSTINCNLIISLITIFHSQVVDM*FNVQERNNQLFFDKIP 137
           AH  ++YG+S ++C ++ SL+++  +Q V   FNV    + L +  IP
Sbjct: 140 AHFGYIYGISVLSCLMMYSLLSLMTAQSV---FNVTTVASVLGYSLIP 184


>UniRef50_Q7QSR2 Cluster: GLP_714_26114_29632; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_714_26114_29632 - Giardia lamblia
           ATCC 50803
          Length = 1172

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
 Frame = +2

Query: 119 EMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGI-KCAT 295
           E+T I+ +L    L+  F DIE+ + ++   N  +  ++     A+   K +  + K  T
Sbjct: 679 ELTEILQNLEVYSLMDTFFDIEIEIANIEHSNMTQALEESRTSLADIQNKLSYALSKTPT 738

Query: 296 ITPDEKRVEEFKL 334
            TPD ++  E  L
Sbjct: 739 FTPDVRKSAEISL 751


>UniRef50_A5E1L5 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 819

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = +2

Query: 107 ILGDEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTID--CAEAIKKYNVG 280
           IL + +T++IW+ I   + IP + +  +     +    K+ + +     C+  IKK NV 
Sbjct: 79  ILAEWITQLIWENIP--VTIPIVQLTANNIWTRLPASVKSGNGIFSQKWCSHFIKKLNVN 136

Query: 281 IKCATITPDEKRVE-EFKLKKMWK 349
           I   T   DEKR    + L K+WK
Sbjct: 137 ITGDTDDKDEKRRNFGYPLNKVWK 160


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 540,815,666
Number of Sequences: 1657284
Number of extensions: 10969874
Number of successful extensions: 28326
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 27521
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28320
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 32619212418
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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