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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ovS302H05f
         (521 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AL139286-4|CAI22804.1|  857|Homo sapiens eukaryotic translation ...    75   2e-13
AL139286-3|CAI22803.1|  782|Homo sapiens eukaryotic translation ...    75   2e-13
AF093097-1|AAF00068.1|  857|Homo sapiens putative RNA-binding pr...    75   2e-13
BC063275-1|AAH63275.1|  857|Homo sapiens eukaryotic translation ...    73   5e-13
BC125213-1|AAI25214.1|  808|Homo sapiens EIF2C2 protein protein.       69   8e-12
AY077717-1|AAL76093.1|  851|Homo sapiens eukaryotic initiation f...    69   8e-12
AL139286-2|CAI22802.1|  860|Homo sapiens eukaryotic translation ...    68   2e-11
AL138787-5|CAI22268.1|  860|Homo sapiens eukaryotic translation ...    68   2e-11
AK022827-1|BAB14262.1|  860|Homo sapiens protein ( Homo sapiens ...    68   2e-11
AL359186-1|CAH71584.1|  861|Homo sapiens eukaryotic translation ...    66   7e-11
AL354864-1|CAH73806.1|  861|Homo sapiens eukaryotic translation ...    66   7e-11
AB046787-1|BAB13393.1|  924|Homo sapiens KIAA1567 protein protein.     66   7e-11
AL139286-1|CAI22801.1|  229|Homo sapiens eukaryotic translation ...    57   4e-08
AK027796-1|BAB55374.1|  229|Homo sapiens protein ( Homo sapiens ...    55   1e-07
BC066888-1|AAH66888.1|  229|Homo sapiens EIF2C3 protein protein.       55   2e-07

>AL139286-4|CAI22804.1|  857|Homo sapiens eukaryotic translation
           initiation factor 2C, 1 protein.
          Length = 857

 Score = 74.5 bits (175), Expect = 2e-13
 Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 2/164 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  KN Y++T LP I  ER   +V I    GKD  F+VS K   IV +   + H A   
Sbjct: 92  YDGKKNIYTVTALP-IGNERVDFEVTIPG-EGKDRIFKVSIKWLAIVSWR--MLHEALVS 147

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPID-LGDGLEMWTGLFQSAIFT 363
             +  P +++Q +D+ ++      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 148 GQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 207

Query: 364 S-KAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPMDRQTRPV 492
             K  +N+DV+   F K QP+I+       +   R +D Q +P+
Sbjct: 208 MWKMMLNIDVSATAFYKAQPVIEFMCEVLDI---RNIDEQPKPL 248


>AL139286-3|CAI22803.1|  782|Homo sapiens eukaryotic translation
           initiation factor 2C, 1 protein.
          Length = 782

 Score = 74.5 bits (175), Expect = 2e-13
 Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 2/164 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  KN Y++T LP I  ER   +V I    GKD  F+VS K   IV +   + H A   
Sbjct: 17  YDGKKNIYTVTALP-IGNERVDFEVTIPG-EGKDRIFKVSIKWLAIVSWR--MLHEALVS 72

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPID-LGDGLEMWTGLFQSAIFT 363
             +  P +++Q +D+ ++      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 73  GQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 132

Query: 364 S-KAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPMDRQTRPV 492
             K  +N+DV+   F K QP+I+       +   R +D Q +P+
Sbjct: 133 MWKMMLNIDVSATAFYKAQPVIEFMCEVLDI---RNIDEQPKPL 173


>AF093097-1|AAF00068.1|  857|Homo sapiens putative RNA-binding
           protein Q99 protein.
          Length = 857

 Score = 74.5 bits (175), Expect = 2e-13
 Identities = 52/164 (31%), Positives = 78/164 (47%), Gaps = 2/164 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  KN Y++T LP I  ER   +V I    GKD  F+VS K   IV +   + H A   
Sbjct: 92  YDGKKNIYTVTALP-IGNERVDFEVTIPG-EGKDRIFKVSIKWLAIVSWR--MLHEALVS 147

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPID-LGDGLEMWTGLFQSAIFT 363
             +  P +++Q +D+ ++      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 148 GQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 207

Query: 364 S-KAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPMDRQTRPV 492
             K  +N+DV+   F K QP+I+       +   R +D Q +P+
Sbjct: 208 MWKMMLNIDVSATAFYKAQPVIEFMCEVLDI---RNIDEQPKPL 248


>BC063275-1|AAH63275.1|  857|Homo sapiens eukaryotic translation
           initiation factor 2C, 1 protein.
          Length = 857

 Score = 73.3 bits (172), Expect = 5e-13
 Identities = 48/143 (33%), Positives = 70/143 (48%), Gaps = 2/143 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  KN Y++T LP I  ER   +V I    GKD  F+VS K   IV +   + H A   
Sbjct: 92  YDGKKNIYTVTALP-IGNERVDFEVTIPG-EGKDRIFKVSIKWLAIVSWR--MLHEALVS 147

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPID-LGDGLEMWTGLFQSAIFT 363
             +  P +++Q +D+ ++      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 148 GQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 207

Query: 364 S-KAFINVDVAHKGFPKNQPMID 429
             K  +N+DV+   F K QP+I+
Sbjct: 208 MWKMMLNIDVSATAFYKAQPVIE 230


>BC125213-1|AAI25214.1|  808|Homo sapiens EIF2C2 protein protein.
          Length = 808

 Score = 69.3 bits (162), Expect = 8e-12
 Identities = 48/143 (33%), Positives = 71/143 (49%), Gaps = 2/143 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           FD  KN Y+  PLP I  ++  ++V +    GKD  F+VS K    V    +  H A  G
Sbjct: 43  FDGRKNLYTAMPLP-IGRDKVELEVTLPG-EGKDRIFKVSIKWVSCVSLQAL--HDALSG 98

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPID-LGDGLEMWTGLFQSAIFT 363
              + P +TIQ +D+V++      Y   GR +F       + LG G E+W G  QS   +
Sbjct: 99  RLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPS 158

Query: 364 S-KAFINVDVAHKGFPKNQPMID 429
             K  +N+DV+   F K QP+I+
Sbjct: 159 LWKMMLNIDVSATAFYKAQPVIE 181


>AY077717-1|AAL76093.1|  851|Homo sapiens eukaryotic initiation
           factor 2C2 protein.
          Length = 851

 Score = 69.3 bits (162), Expect = 8e-12
 Identities = 48/143 (33%), Positives = 71/143 (49%), Gaps = 2/143 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           FD  KN Y+  PLP I  ++  ++V +    GKD  F+VS K    V    +  H A  G
Sbjct: 86  FDGRKNLYTAMPLP-IGRDKVELEVTLPG-EGKDRIFKVSIKWVSCVSLQAL--HDALSG 141

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPID-LGDGLEMWTGLFQSAIFT 363
              + P +TIQ +D+V++      Y   GR +F       + LG G E+W G  QS   +
Sbjct: 142 RLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPS 201

Query: 364 S-KAFINVDVAHKGFPKNQPMID 429
             K  +N+DV+   F K QP+I+
Sbjct: 202 LWKMMLNIDVSATAFYKAQPVIE 224


>AL139286-2|CAI22802.1|  860|Homo sapiens eukaryotic translation
           initiation factor 2C, 3 protein.
          Length = 860

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  ++ Y+  PLP  TT    + V +    GKD PF+VS K    V + ++L  + TG 
Sbjct: 86  YDGKRSLYTANPLPVATTG-VDLDVTLPGEGGKDRPFKVSIKFVSRVSW-HLLHEVLTGR 143

Query: 187 S-----SLNAP--TDTIQCIDIVLKQGTLESYVKAGRQYFMRPAS-PIDLGDGLEMWTGL 342
           +      L+ P  T+ +  +D+VL+      Y   GR +F  P      LG G E+W G 
Sbjct: 144 TLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

Query: 343 FQSAIFTS-KAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPMDRQTRPV 492
            QS      K  +N+DV+   F K QP+I        LD +  +D Q RP+
Sbjct: 204 HQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCE--VLDIHN-IDEQPRPL 251


>AL138787-5|CAI22268.1|  860|Homo sapiens eukaryotic translation
           initiation factor 2C, 3 protein.
          Length = 860

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  ++ Y+  PLP  TT    + V +    GKD PF+VS K    V + ++L  + TG 
Sbjct: 86  YDGKRSLYTANPLPVATTG-VDLDVTLPGEGGKDRPFKVSIKFVSRVSW-HLLHEVLTGR 143

Query: 187 S-----SLNAP--TDTIQCIDIVLKQGTLESYVKAGRQYFMRPAS-PIDLGDGLEMWTGL 342
           +      L+ P  T+ +  +D+VL+      Y   GR +F  P      LG G E+W G 
Sbjct: 144 TLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

Query: 343 FQSAIFTS-KAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPMDRQTRPV 492
            QS      K  +N+DV+   F K QP+I        LD +  +D Q RP+
Sbjct: 204 HQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCE--VLDIHN-IDEQPRPL 251


>AK022827-1|BAB14262.1|  860|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12765 fis, clone NT2RP2001511, moderately
           similar to Homo sapiens putative RNA-binding protein Q99
           mRNA. ).
          Length = 860

 Score = 67.7 bits (158), Expect = 2e-11
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  ++ Y+  PLP  TT    + V +    GKD PF+VS K    V + ++L  + TG 
Sbjct: 86  YDGKRSLYTANPLPVATTG-VDLDVTLPGEGGKDRPFKVSIKFVSRVSW-HLLHEVLTGR 143

Query: 187 S-----SLNAP--TDTIQCIDIVLKQGTLESYVKAGRQYFMRPAS-PIDLGDGLEMWTGL 342
           +      L+ P  T+ +  +D+VL+      Y   GR +F  P      LG G E+W G 
Sbjct: 144 TLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

Query: 343 FQSAIFTS-KAFINVDVAHKGFPKNQPMIDAFTRDFRLDPNRPMDRQTRPV 492
            QS      K  +N+DV+   F K QP+I        LD +  +D Q RP+
Sbjct: 204 HQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCE--VLDIHN-IDEQPRPL 251


>AL359186-1|CAH71584.1|  861|Homo sapiens eukaryotic translation
           initiation factor 2C, 4 protein.
          Length = 861

 Score = 66.1 bits (154), Expect = 7e-11
 Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 2/143 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  +N Y+  PLP I  +R  ++V +    GKD  F+VS +   +V    +L+ +A  G
Sbjct: 84  YDGKRNMYTAHPLP-IGRDRVDMEVTLPG-EGKDQTFKVSVQWVSVVSLQLLLEALA--G 139

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPI-DLGDGLEMWTGLFQSAIFT 363
                P D++Q +D++ +      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 140 HLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 199

Query: 364 S-KAFINVDVAHKGFPKNQPMID 429
                +N+DV+   F + QP+I+
Sbjct: 200 MWNMMLNIDVSATAFYRAQPIIE 222


>AL354864-1|CAH73806.1|  861|Homo sapiens eukaryotic translation
           initiation factor 2C, 4 protein.
          Length = 861

 Score = 66.1 bits (154), Expect = 7e-11
 Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 2/143 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  +N Y+  PLP I  +R  ++V +    GKD  F+VS +   +V    +L+ +A  G
Sbjct: 84  YDGKRNMYTAHPLP-IGRDRVDMEVTLPG-EGKDQTFKVSVQWVSVVSLQLLLEALA--G 139

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPI-DLGDGLEMWTGLFQSAIFT 363
                P D++Q +D++ +      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 140 HLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 199

Query: 364 S-KAFINVDVAHKGFPKNQPMID 429
                +N+DV+   F + QP+I+
Sbjct: 200 MWNMMLNIDVSATAFYRAQPIIE 222


>AB046787-1|BAB13393.1|  924|Homo sapiens KIAA1567 protein protein.
          Length = 924

 Score = 66.1 bits (154), Expect = 7e-11
 Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 2/143 (1%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  +N Y+  PLP I  +R  ++V +    GKD  F+VS +   +V    +L+ +A  G
Sbjct: 147 YDGKRNMYTAHPLP-IGRDRVDMEVTLPG-EGKDQTFKVSVQWVSVVSLQLLLEALA--G 202

Query: 187 SSLNAPTDTIQCIDIVLKQGTLESYVKAGRQYFMRPASPI-DLGDGLEMWTGLFQSAIFT 363
                P D++Q +D++ +      Y   GR +F  P      LG G E+W G  QS    
Sbjct: 203 HLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPA 262

Query: 364 S-KAFINVDVAHKGFPKNQPMID 429
                +N+DV+   F + QP+I+
Sbjct: 263 MWNMMLNIDVSATAFYRAQPIIE 285


>AL139286-1|CAI22801.1|  229|Homo sapiens eukaryotic translation
           initiation factor 2C, 3 protein.
          Length = 229

 Score = 56.8 bits (131), Expect = 4e-08
 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 9/136 (6%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  ++ Y+  PLP  TT    + V +    GKD PF+VS K    V + ++L  + TG 
Sbjct: 86  YDGKRSLYTANPLPVATTG-VDLDVTLPGEGGKDRPFKVSIKFVSRVSW-HLLHEVLTGR 143

Query: 187 S-----SLNAP--TDTIQCIDIVLKQGTLESYVKAGRQYFMRPAS-PIDLGDGLEMWTGL 342
           +      L+ P  T+ +  +D+VL+      Y   GR +F  P      LG G E+W G 
Sbjct: 144 TLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

Query: 343 FQSAIFTS-KAFINVD 387
            QS      K  +N+D
Sbjct: 204 HQSVRPAMWKMMLNID 219


>AK027796-1|BAB55374.1|  229|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14890 fis, clone PLACE1004149, weakly similar to
           Rattus norvegicus GERp95 mRNA. ).
          Length = 229

 Score = 55.2 bits (127), Expect = 1e-07
 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 9/136 (6%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           +D  ++ Y+  PLP  TT    + V +    GKD PF+VS K    V + ++L  + TG 
Sbjct: 86  YDGKRSLYTANPLPVATTG-VDLDVTLPGEGGKDRPFKVSIKFVSRVSW-HLLHEVLTGR 143

Query: 187 S-----SLNAP--TDTIQCIDIVLKQGTLESYVKAGRQYFMRPAS-PIDLGDGLEMWTGL 342
           +      L+ P  T+    +D+VL+      Y   GR +F  P      LG G E+W G 
Sbjct: 144 TLPEPLELDKPISTNPAHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

Query: 343 FQSAIFTS-KAFINVD 387
            QS      K  +N+D
Sbjct: 204 HQSVRPAMWKMMLNID 219


>BC066888-1|AAH66888.1|  229|Homo sapiens EIF2C3 protein protein.
          Length = 229

 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 9/136 (6%)
 Frame = +1

Query: 7   FDQTKNCYSLTPLPKITTERYGVKVVIKDMNGKDMPFEVSFKASGIVDYNNVLKHMATGG 186
           ++  ++ Y+  PLP  TT    + V +    GKD PF+VS K    V + ++L  + TG 
Sbjct: 86  YNGKRSLYTANPLPVATTG-VDLDVTLPGEGGKDRPFKVSIKFVSRVSW-HLLHEVLTGR 143

Query: 187 S-----SLNAP--TDTIQCIDIVLKQGTLESYVKAGRQYFMRPAS-PIDLGDGLEMWTGL 342
           +      L+ P  T+ +  +D+VL+      Y   GR +F  P      LG G E+W G 
Sbjct: 144 TLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

Query: 343 FQSAIFTS-KAFINVD 387
            QS      K  +N+D
Sbjct: 204 HQSVRPAMWKMMLNID 219


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,363,921
Number of Sequences: 237096
Number of extensions: 1902604
Number of successful extensions: 3114
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3016
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3104
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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