Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS302G11f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 120 2e-27
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 120 2e-27
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 120 2e-27
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 120 2e-27
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 118 1e-26
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 99 5e-21
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 99 8e-21
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 93 7e-19
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 92 9e-19
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 92 9e-19
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 92 9e-19
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 92 9e-19
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 88 2e-17
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 88 2e-17
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 88 2e-17
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 88 2e-17
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 88 2e-17
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 88 2e-17
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 88 2e-17
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 88 2e-17
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 88 2e-17
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 85 1e-16
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 85 1e-16
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 85 1e-16
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 83 6e-16
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 82 1e-15
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 82 1e-15
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 82 1e-15
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 81 2e-15
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 80 4e-15
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 80 4e-15
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 80 4e-15
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 80 4e-15
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 80 4e-15
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 80 4e-15
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 80 4e-15
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 80 4e-15
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 80 4e-15
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 80 4e-15
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 80 4e-15
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 80 4e-15
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 80 4e-15
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 80 4e-15
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 79 7e-15
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 79 7e-15
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 79 7e-15
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 79 7e-15
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 79 7e-15
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 79 7e-15
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 78 2e-14
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 78 2e-14
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 78 2e-14
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 78 2e-14
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 78 2e-14
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 76 7e-14
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 1e-13
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 75 2e-13
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 75 2e-13
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 75 2e-13
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 75 2e-13
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 75 2e-13
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 75 2e-13
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 75 2e-13
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 75 2e-13
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 75 2e-13
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 75 2e-13
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 75 2e-13
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 75 2e-13
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 75 2e-13
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 75 2e-13
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 75 2e-13
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 75 2e-13
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 75 2e-13
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 75 2e-13
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 75 2e-13
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 74 4e-13
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 74 4e-13
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 74 4e-13
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 74 4e-13
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 73 5e-13
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 73 6e-13
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 71 2e-12
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 70 4e-12
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 70 4e-12
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 70 4e-12
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 69 1e-11
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 69 1e-11
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 69 1e-11
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 69 1e-11
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 67 3e-11
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 67 3e-11
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 66 5e-11
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 66 5e-11
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 66 5e-11
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 66 7e-11
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 66 7e-11
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 66 7e-11
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 66 7e-11
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 66 7e-11
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 66 9e-11
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 66 9e-11
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 66 9e-11
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 66 9e-11
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 65 1e-10
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 65 2e-10
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 65 2e-10
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 65 2e-10
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 65 2e-10
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 65 2e-10
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 65 2e-10
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 65 2e-10
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 65 2e-10
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 65 2e-10
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 64 2e-10
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 64 2e-10
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 64 3e-10
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 64 4e-10
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 63 5e-10
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 63 5e-10
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 62 1e-09
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 62 1e-09
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 62 1e-09
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 62 2e-09
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 60 3e-09
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 60 3e-09
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 60 3e-09
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 60 3e-09
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 60 6e-09
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 60 6e-09
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 60 6e-09
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 60 6e-09
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 60 6e-09
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 6e-09
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 60 6e-09
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 60 6e-09
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 60 6e-09
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 60 6e-09
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 60 6e-09
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 60 6e-09
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 60 6e-09
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 60 6e-09
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 60 6e-09
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 60 6e-09
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 59 8e-09
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 59 8e-09
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 59 8e-09
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 59 8e-09
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 59 8e-09
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 59 8e-09
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 59 8e-09
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 59 8e-09
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 59 8e-09
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 59 8e-09
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 59 8e-09
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 59 8e-09
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 58 1e-08
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 58 2e-08
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 58 2e-08
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 58 2e-08
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 58 2e-08
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 58 2e-08
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 58 2e-08
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 57 3e-08
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 57 3e-08
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 57 3e-08
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 57 3e-08
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 57 3e-08
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 57 3e-08
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 56 8e-08
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 56 8e-08
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 56 8e-08
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 56 8e-08
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 56 8e-08
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 56 8e-08
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 56 8e-08
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 56 8e-08
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 56 8e-08
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 56 8e-08
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 56 8e-08
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 56 8e-08
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 56 8e-08
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 56 8e-08
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 56 1e-07
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 56 1e-07
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 56 1e-07
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 56 1e-07
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 55 2e-07
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 55 2e-07
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 55 2e-07
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 55 2e-07
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 55 2e-07
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 54 2e-07
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 54 2e-07
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 54 2e-07
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 54 3e-07
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 54 4e-07
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 54 4e-07
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 53 5e-07
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 53 5e-07
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 53 5e-07
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 53 5e-07
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 53 5e-07
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 53 5e-07
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 53 5e-07
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 53 5e-07
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 53 5e-07
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 53 5e-07
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 53 5e-07
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 53 5e-07
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 53 7e-07
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 53 7e-07
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 53 7e-07
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 53 7e-07
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 53 7e-07
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 53 7e-07
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 53 7e-07
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 53 7e-07
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 53 7e-07
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 53 7e-07
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 53 7e-07
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 52 9e-07
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 52 9e-07
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 52 9e-07
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 52 9e-07
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 52 1e-06
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 52 1e-06
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 52 1e-06
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 52 1e-06
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 52 1e-06
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 52 1e-06
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 52 1e-06
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 52 1e-06
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 52 1e-06
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 52 1e-06
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 52 1e-06
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 52 1e-06
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 52 1e-06
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 52 1e-06
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 52 1e-06
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 52 1e-06
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 52 2e-06
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 52 2e-06
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 52 2e-06
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 52 2e-06
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 52 2e-06
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 52 2e-06
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 52 2e-06
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 52 2e-06
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 52 2e-06
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 52 2e-06
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 52 2e-06
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 52 2e-06
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 51 2e-06
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 51 2e-06
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 51 2e-06
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 51 2e-06
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 51 2e-06
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 51 2e-06
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 51 2e-06
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 51 2e-06
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 51 2e-06
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 51 2e-06
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 51 3e-06
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 51 3e-06
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 50 4e-06
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 50 5e-06
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 50 7e-06
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 50 7e-06
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 50 7e-06
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 50 7e-06
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 50 7e-06
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 50 7e-06
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 50 7e-06
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 49 9e-06
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 49 9e-06
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 49 9e-06
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 49 1e-05
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 48 2e-05
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 48 2e-05
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 47 3e-05
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 46 6e-05
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 46 6e-05
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 46 6e-05
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 46 8e-05
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 46 8e-05
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 46 8e-05
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 46 8e-05
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 46 8e-05
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 46 8e-05
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 46 8e-05
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 46 8e-05
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 46 8e-05
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 46 8e-05
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 46 8e-05
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 46 8e-05
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 46 1e-04
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 46 1e-04
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 45 1e-04
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 45 1e-04
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 45 1e-04
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 45 1e-04
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 45 1e-04
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 45 1e-04
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 45 1e-04
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 45 1e-04
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 45 1e-04
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 45 1e-04
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 45 1e-04
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 45 2e-04
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 45 2e-04
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 45 2e-04
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 45 2e-04
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 45 2e-04
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 45 2e-04
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 45 2e-04
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 45 2e-04
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 45 2e-04
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 45 2e-04
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 44 2e-04
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 44 3e-04
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 44 3e-04
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 44 3e-04
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 44 3e-04
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 44 3e-04
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 44 3e-04
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 44 4e-04
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 44 4e-04
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 44 4e-04
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 44 4e-04
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 43 6e-04
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 43 8e-04
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 43 8e-04
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 43 8e-04
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 43 8e-04
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 42 0.001
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 42 0.001
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 42 0.001
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 42 0.002
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 42 0.002
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 39 0.012
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 36 0.086
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 36 0.086
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 36 0.086
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 36 0.086
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 36 0.086
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 36 0.086
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 36 0.086
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 36 0.086
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 36 0.086
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 36 0.086
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 36 0.086
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 35 0.15
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 34 0.26
U30897-1|AAC51280.1| 210|Homo sapiens glutathione S-transferase... 34 0.35
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 34 0.35
BC010915-1|AAH10915.1| 210|Homo sapiens glutathione S-transfera... 34 0.35
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 34 0.35
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 34 0.35
X15480-1|CAA33508.1| 210|Homo sapiens protein ( Human mRNA for ... 33 0.46
X08094-1|CAA30894.1| 210|Homo sapiens glutathione S-transferase... 33 0.46
X08058-1|CAA30847.1| 210|Homo sapiens gst-pi protein protein. 33 0.46
X06547-1|CAA29794.1| 210|Homo sapiens protein ( Human mRNA for ... 33 0.46
U12472-1|AAA64919.1| 210|Homo sapiens glutathione S-transferase... 33 0.46
M24485-1|AAA56823.1| 210|Homo sapiens glutathione S-transferase... 33 0.46
CR450361-1|CAG29357.1| 210|Homo sapiens GSTP1 protein. 33 0.46
BT019950-1|AAV38753.1| 210|Homo sapiens glutathione S-transfera... 33 0.46
BT019949-1|AAV38752.1| 210|Homo sapiens glutathione S-transfera... 33 0.46
AY324387-1|AAP72967.1| 210|Homo sapiens glutathione S-transfera... 33 0.46
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 33 0.61
U62589-1|AAC51237.1| 210|Homo sapiens glutathione S-transferase... 33 0.80
U21689-1|AAC13869.1| 210|Homo sapiens glutathione S-transferase... 33 0.80
BC029155-1|AAH29155.1| 489|Homo sapiens CYP7B1 protein protein. 30 5.7
D31766-1|BAA06544.2| 317|Homo sapiens KIAA0060 protein. 29 9.9
BC022322-1|AAH22322.1| 289|Homo sapiens glucosamine-6-phosphate... 29 9.9
BC020769-1|AAH20769.1| 289|Homo sapiens glucosamine-6-phosphate... 29 9.9
BC012853-1|AAH12853.1| 289|Homo sapiens glucosamine-6-phosphate... 29 9.9
AJ002231-1|CAA05259.1| 289|Homo sapiens oscillin protein. 29 9.9
AF048826-1|AAC05123.1| 289|Homo sapiens glucosamine-6-phosphate... 29 9.9
AF035809-1|AAB88748.1| 289|Homo sapiens oscillin protein. 29 9.9
AF029914-1|AAB84217.1| 289|Homo sapiens oscillin protein. 29 9.9
AC005740-1|AAC62119.1| 289|Homo sapiens oscillin protein. 29 9.9
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 120 bits (290), Expect = 2e-27
Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 4/169 (2%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 54 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 113
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW 374
L P ++A + E+ RL P+ PF R LD +G + +P GT ++ +T E+NF
Sbjct: 114 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 173
Query: 375 RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ ++ PERW++ +E PFG G+RMC G+R EL+LHL L I
Sbjct: 174 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWI 222
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 120 bits (290), Expect = 2e-27
Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 4/169 (2%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 228
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW 374
L P ++A + E+ RL P+ PF R LD +G + +P GT ++ +T E+NF
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 288
Query: 375 RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ ++ PERW++ +E PFG G+RMC G+R EL+LHL L I
Sbjct: 289 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWI 337
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 120 bits (290), Expect = 2e-27
Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 4/169 (2%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW 374
L P ++A + E+ RL P+ PF R LD +G + +P GT ++ +T E+NF
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 430
Query: 375 RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ ++ PERW++ +E PFG G+RMC G+R EL+LHL L I
Sbjct: 431 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWI 479
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 120 bits (290), Expect = 2e-27
Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 4/169 (2%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 228
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW 374
L P ++A + E+ RL P+ PF R LD +G + +P GT ++ +T E+NF
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 288
Query: 375 RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ ++ PERW++ +E PFG G+RMC G+R EL+LHL L I
Sbjct: 289 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWI 337
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 118 bits (284), Expect = 1e-26
Identities = 64/169 (37%), Positives = 93/169 (55%), Gaps = 4/169 (2%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP ED
Sbjct: 310 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREED 369
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW 374
L P ++A + E+ RL P PF R LD +G + +P GT ++ +T E+NF
Sbjct: 370 LRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 429
Query: 375 RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ ++ PERW++ +E PFG G+RMC G+R EL+LHL L I
Sbjct: 430 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWI 478
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 99 bits (238), Expect = 5e-21
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 7/173 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQ----RKINSELPPYAMLCSE 191
AL +++ A + + + AG++T + +L + +YLL+ P+ Q R+I L + +
Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAA 223
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAACRREEN 368
D+ P VRA + E RL P P R+ + IGG+ IP GT L H A + + +EN
Sbjct: 224 DVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQ-DEN 282
Query: 369 FWRAEEYLPERWIKVQEPHAYSLVA--PFGRGRRMCPGKRFVELELHLLLAKI 521
F RA+E+ PERW++ + PFG G R C G+R ELE+HL++ ++
Sbjct: 283 FPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQL 335
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 99.1 bits (236), Expect = 8e-21
Identities = 58/173 (33%), Positives = 95/173 (54%), Gaps = 7/173 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQ----RKINSELPPYAMLCSE 191
AL +++ A + + + AG++T + +L + +Y+L+ P+ Q R+I L + +
Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPTAA 223
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAACRREEN 368
D+ P VRA + E RL P P R+ + IGG+ IP GT L H A + + +EN
Sbjct: 224 DVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQ-DEN 282
Query: 369 FWRAEEYLPERWIKVQEPHAYSLVA--PFGRGRRMCPGKRFVELELHLLLAKI 521
F RA+E+ PERW++ + PFG G R C G+R ELE+HL++ ++
Sbjct: 283 FPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQL 335
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 92.7 bits (220), Expect = 7e-19
Identities = 56/182 (30%), Positives = 94/182 (51%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 ILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSEL----PPYA 176
+L + L R+ ++ + + AG++T +N+L + LY LS P+ Q+ ++ E+ P
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQ 373
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAAC 353
+ +D A P ++A + E RL P P +R+++ + + G P T FV H +
Sbjct: 374 VPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVS- 432
Query: 354 RREENFWRAEEYLPERWIKVQEP------HAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
R F E + P RW++ +P H + V PFG G R C G+R ELE+ LLLA
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSV-PFGYGVRACLGRRIAELEMQLLLA 491
Query: 516 KI 521
++
Sbjct: 492 RL 493
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 92.3 bits (219), Expect = 9e-19
Identities = 56/182 (30%), Positives = 93/182 (51%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 ILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSEL----PPYA 176
+L + L R+ ++ + + AG++T +N+L + LY LS P+ Q ++ E+ P
Sbjct: 313 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 372
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAAC 353
+ +D A P ++A + E RL P P +R+++ + + G P T FV H +
Sbjct: 373 VPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS- 431
Query: 354 RREENFWRAEEYLPERWIKVQEP------HAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
R F E + P RW++ +P H + V PFG G R C G+R ELE+ LLLA
Sbjct: 432 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSV-PFGYGVRACLGRRIAELEMQLLLA 490
Query: 516 KI 521
++
Sbjct: 491 RL 492
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 92.3 bits (219), Expect = 9e-19
Identities = 56/182 (30%), Positives = 93/182 (51%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 ILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSEL----PPYA 176
+L + L R+ ++ + + AG++T +N+L + LY LS P+ Q ++ E+ P
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 373
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAAC 353
+ +D A P ++A + E RL P P +R+++ + + G P T FV H +
Sbjct: 374 VPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS- 432
Query: 354 RREENFWRAEEYLPERWIKVQEP------HAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
R F E + P RW++ +P H + V PFG G R C G+R ELE+ LLLA
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSV-PFGYGVRACLGRRIAELEMQLLLA 491
Query: 516 KI 521
++
Sbjct: 492 RL 493
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 92.3 bits (219), Expect = 9e-19
Identities = 56/182 (30%), Positives = 93/182 (51%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 ILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSEL----PPYA 176
+L + L R+ ++ + + AG++T +N+L + LY LS P+ Q ++ E+ P
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 373
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAAC 353
+ +D A P ++A + E RL P P +R+++ + + G P T FV H +
Sbjct: 374 VPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS- 432
Query: 354 RREENFWRAEEYLPERWIKVQEP------HAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
R F E + P RW++ +P H + V PFG G R C G+R ELE+ LLLA
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSV-PFGYGVRACLGRRIAELEMQLLLA 491
Query: 516 KI 521
++
Sbjct: 492 RL 493
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 92.3 bits (219), Expect = 9e-19
Identities = 56/182 (30%), Positives = 93/182 (51%), Gaps = 11/182 (6%)
Frame = +3
Query: 9 ILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSEL----PPYA 176
+L + L R+ ++ + + AG++T +N+L + LY LS P+ Q ++ E+ P
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 373
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGT-FVLAHTAAAC 353
+ +D A P ++A + E RL P P +R+++ + + G P T FV H +
Sbjct: 374 VPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS- 432
Query: 354 RREENFWRAEEYLPERWIKVQEP------HAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
R F E + P RW++ +P H + V PFG G R C G+R ELE+ LLLA
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSV-PFGYGVRACLGRRIAELEMQLLLA 491
Query: 516 KI 521
++
Sbjct: 492 RL 493
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 88.2 bits (209), Expect = 2e-17
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPP--YAMLCSEDLAGAPSV 215
+ + + AG++T++N+L + LY LS P+ Q ++SE L P A + L+ P +
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
+A + E RL P P +R+ D + +G + IP T V A R F + P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 396 ERWI-KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
RW+ + PH ++ + PFG G+R C G+R ELEL + LA+I
Sbjct: 431 ARWLGEGPTPHPFASL-PFGFGKRSCMGRRLAELELQMALAQI 472
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 85.0 bits (201), Expect = 1e-16
Identities = 55/173 (31%), Positives = 81/173 (46%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L L + KA ++ ++T A L+ L+ L+ PD Q+ + E A
Sbjct: 292 ELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R++ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLL 464
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 85.0 bits (201), Expect = 1e-16
Identities = 55/173 (31%), Positives = 81/173 (46%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L L + KA ++ ++T A L+ L+ L+ PD Q+ + E A
Sbjct: 292 ELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R++ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNAALFPRPERYNPQRWLDIRGSGRNLHHVPFGFGMRQCLGRRLAEAEMLLLL 464
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 85.0 bits (201), Expect = 1e-16
Identities = 55/173 (31%), Positives = 81/173 (46%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L L + KA ++ ++T A L+ L+ L+ PD Q+ + E A
Sbjct: 292 ELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R++ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLL 464
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 83.0 bits (196), Expect = 6e-16
Identities = 54/173 (31%), Positives = 80/173 (46%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L N L KA ++ ++T L+ L+ L+ P+ Q+ + E A
Sbjct: 292 ELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R++ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVRVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLL 464
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 82.2 bits (194), Expect = 1e-15
Identities = 54/173 (31%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L N L KA ++ ++T L+ L+ L+ P+ Q+ + E A
Sbjct: 292 ELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R+ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLL 464
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 82.2 bits (194), Expect = 1e-15
Identities = 54/173 (31%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L N L KA ++ ++T L+ L+ L+ P+ Q+ + E A
Sbjct: 292 ELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R+ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLL 464
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 82.2 bits (194), Expect = 1e-15
Identities = 54/173 (31%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L N L KA ++ ++T L+ L+ L+ P+ Q+ + E A
Sbjct: 363 ELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASI 422
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R+ S + + + IP GT V +
Sbjct: 423 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLG 482
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 483 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLL 535
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 81.4 bits (192), Expect = 2e-15
Identities = 54/173 (31%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L N L KA ++ ++T L+ L+ L+ P+ Q+ + E A
Sbjct: 292 ELLLNAELSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASI 351
Query: 186 SEDLAGA----PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
SE A P +RAA+ E RL P FL R+ S + + + IP GT V +
Sbjct: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLG 411
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E E+ LLL
Sbjct: 412 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLL 464
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 80.2 bits (189), Expect = 4e-15
Identities = 57/171 (33%), Positives = 81/171 (47%), Gaps = 5/171 (2%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F LY L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R + I G IP G+ V+ T A + +
Sbjct: 349 AVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYAL-HHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
W EE+ PER+ K ++ + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 458
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 80.2 bits (189), Expect = 4e-15
Identities = 57/171 (33%), Positives = 81/171 (47%), Gaps = 5/171 (2%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F LY L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R + I G IP G+ V+ T A + +
Sbjct: 349 AVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYAL-HHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
W EE+ PER+ K ++ + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 458
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 139 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 198
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 199 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 257
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 258 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 309
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 216 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 275
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 276 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 334
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 335 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 386
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 80.2 bits (189), Expect = 4e-15
Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI-PSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 80.2 bits (189), Expect = 4e-15
Identities = 57/171 (33%), Positives = 81/171 (47%), Gaps = 5/171 (2%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F LY L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R + I G IP G+ V+ T A + +
Sbjct: 349 AVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYAL-HHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
W EE+ PER+ K ++ + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 458
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 79.4 bits (187), Expect = 7e-15
Identities = 56/172 (32%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G +V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG-WVVMIPSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 459
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 79.4 bits (187), Expect = 7e-15
Identities = 58/175 (33%), Positives = 87/175 (49%), Gaps = 9/175 (5%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G +V+ + A R+ +
Sbjct: 349 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG-WVVMIPSYALHRDPKY 407
Query: 372 W-RAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K +P+ Y+ PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYTYT---PFGSGPRNCIGMRFALMNMKLALIRV 459
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 79.4 bits (187), Expect = 7e-15
Identities = 56/172 (32%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 349
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G +V+ + A R+ +
Sbjct: 350 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG-WVVMIPSYALHRDPKY 408
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 460
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 79.4 bits (187), Expect = 7e-15
Identities = 58/175 (33%), Positives = 87/175 (49%), Gaps = 9/175 (5%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 288 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 347
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G +V+ + A R+ +
Sbjct: 348 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG-WVVMIPSYALHRDPKY 406
Query: 372 W-RAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K +P+ Y+ PFG G R C G RF + + L L ++
Sbjct: 407 WTEPEKFLPERFSKKNKDNIDPYTYT---PFGSGPRNCIGMRFALMNMKLALIRV 458
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 79.4 bits (187), Expect = 7e-15
Identities = 56/172 (32%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYD 349
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G +V+ + A R+ +
Sbjct: 350 TVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG-WVVMIPSYALHRDPKY 408
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRV 460
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 79.4 bits (187), Expect = 7e-15
Identities = 57/171 (33%), Positives = 81/171 (47%), Gaps = 5/171 (2%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F LY L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R + I G IP G+ V+ T A + +
Sbjct: 349 AVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYAL-HHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
W EE+ PER+ K ++ + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 458
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 77.8 bits (183), Expect = 2e-14
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE-LPPYAML 182
++L N L KA ++ ++ L+ L+ L+ P+ Q+ + E L P A +
Sbjct: 82 ELLLNAELSPDAIKANCMELTAGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAASI 141
Query: 183 CSEDLAGA---PSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
P +RAA+ E RL P L R++ S + + + IP GT V +
Sbjct: 142 SEHPQKATTELPLLRAALKETLRLYPVGLILERVVSSDLVLQNYHIPAGTLVRVFLYSLG 201
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F R E Y P+RW+ ++ PFG G R C G+R E ++ LLL
Sbjct: 202 RNPALFPRPERYNPQRWLDIKGSGRNFYHVPFGFGMRQCLGRRLAEADMLLLL 254
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 77.8 bits (183), Expect = 2e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + + +
Sbjct: 349 TVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI-PSYVLHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRV 459
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 77.8 bits (183), Expect = 2e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + + +
Sbjct: 349 TVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI-PSYVLHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRV 459
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 77.8 bits (183), Expect = 2e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + + +
Sbjct: 349 TVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI-PSYVLHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRV 459
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 77.8 bits (183), Expect = 2e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I FI AG ET ++ L F++Y L+ PD Q+K+ E LP A +
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
+ + +NE RL P A L R+ + I G IP G V+ + + +
Sbjct: 349 TVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI-PSYVLHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSLV-APFGRGRRMCPGKRFVELELHLLLAKI 521
W E++LPER+ K + + + PFG G R C G RF + + L L ++
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRV 459
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 76.2 bits (179), Expect = 7e-14
Identities = 56/166 (33%), Positives = 82/166 (49%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSL----VFLLYLLSGRPDWQRKINSELPPYAMLCS---EDLAGAP 209
A +D + G ET AN+L VFLL+ L + Q +++ EL P A +D A P
Sbjct: 20 AAVDLLIGGTETTANTLSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVPYKDRARLP 79
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 80 LLIATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 138
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 139 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 181
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 75.4 bits (177), Expect = 1e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 254 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 313
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 314 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 372
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 373 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 415
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 255 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 314
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 315 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 373
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 374 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 416
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 255 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 314
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 315 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 373
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 374 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 416
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 255 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 314
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 315 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 373
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 374 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 416
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 193 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 252
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 253 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 311
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 312 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 354
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 74.9 bits (176), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 74.5 bits (175), Expect = 2e-13
Identities = 53/166 (31%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 285 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLP 344
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 345 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 403
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 404 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 446
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 74.5 bits (175), Expect = 2e-13
Identities = 55/166 (33%), Positives = 81/166 (48%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSL----VFLLYLLSGRPDWQRKINSELPPYAMLCS---EDLAGAP 209
A +D + G ET AN+L VFLL+ + Q +++ EL P A +D A P
Sbjct: 255 AAVDLLIGGTETTANTLSWAAVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 314
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 315 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 373
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 374 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 416
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 73.7 bits (173), Expect = 4e-13
Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 7/176 (3%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY-----AM 179
E L D + + F+ G +T A ++ + LYLL P+ Q+K++ EL
Sbjct: 310 EGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRP 369
Query: 180 LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
EDL + I E RL P+ P AR + + G+++ GT + A R
Sbjct: 370 ATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRD 429
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ PER+ Q H Y+ V PF G R C G++F +E +L+ I
Sbjct: 430 PRYFPNPEEFQPERFFPENAQGRHPYAYV-PFSAGPRNCIGQKFAVMEEKTILSCI 484
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 73.7 bits (173), Expect = 4e-13
Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 7/176 (3%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY-----AM 179
E L D + + F+ G +T A ++ + LYLL P+ Q+K++ EL
Sbjct: 310 EGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRP 369
Query: 180 LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
EDL + I E RL P+ P AR + + G+++ GT + A R
Sbjct: 370 ATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRD 429
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ PER+ Q H Y+ V PF G R C G++F +E +L+ I
Sbjct: 430 PRYFPNPEEFQPERFFPENAQGRHPYAYV-PFSAGPRNCIGQKFAVMEEKTILSCI 484
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 73.7 bits (173), Expect = 4e-13
Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 7/176 (3%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY-----AM 179
E L D + + F+ G +T A ++ + LYLL P+ Q+K++ EL
Sbjct: 288 EGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRP 347
Query: 180 LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
EDL + I E RL P+ P AR + + G+++ GT + A R
Sbjct: 348 ATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRD 407
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ PER+ Q H Y+ V PF G R C G++F +E +L+ I
Sbjct: 408 PRYFPNPEEFQPERFFPENAQGRHPYAYV-PFSAGPRNCIGQKFAVMEEKTILSCI 462
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 73.7 bits (173), Expect = 4e-13
Identities = 52/176 (29%), Positives = 79/176 (44%), Gaps = 7/176 (3%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY-----AM 179
E L D + + F+ G +T A ++ + LYLL P+ Q+K++ EL
Sbjct: 310 EGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRP 369
Query: 180 LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
EDL + I E RL P+ P AR + + G+++ GT + A R
Sbjct: 370 ATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRD 429
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ PER+ Q H Y+ V PF G R C G++F +E +L+ I
Sbjct: 430 PRYFPNPEEFQPERFFPENAQGRHPYAYV-PFSAGPRNCIGQKFAVMEEKTILSCI 484
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 73.3 bits (172), Expect = 5e-13
Identities = 52/166 (31%), Positives = 79/166 (47%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGT-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 72.9 bits (171), Expect = 6e-13
Identities = 52/166 (31%), Positives = 79/166 (47%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G E AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTENTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G R+C G+ LEL ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGARVCLGEPLARLELFVVLTRL 445
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 70.9 bits (166), Expect = 2e-12
Identities = 51/166 (30%), Positives = 79/166 (47%), Gaps = 9/166 (5%)
Frame = +3
Query: 51 AIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCS---EDLAGAP 209
A +D + G ET AN+L + + L P+ Q+++ EL P A +D A P
Sbjct: 284 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 343
Query: 210 SVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAE 383
+ A I E RL P P L P +I G+ IP GT ++ + A +E W R
Sbjct: 344 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA-HLDETVWERPH 402
Query: 384 EYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E+ P+R++ EP S FG G +C G+ L+L ++L ++
Sbjct: 403 EFWPDRFL---EPGKNSRALAFGCGAPVCLGEPLARLDLFVVLTRL 445
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 70.1 bits (164), Expect = 4e-12
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPG 320
L P ++A + E+ RL P+ PF R LD +G + +P G
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKG 412
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 70.1 bits (164), Expect = 4e-12
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPG 320
L P ++A + E+ RL P+ PF R LD +G + +P G
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKG 412
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 70.1 bits (164), Expect = 4e-12
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYAMLCSED 194
L ++ AA+ + A +ET ANSL+++LY LS P Q+K I S LP + +ED
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 195 LAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPG 320
L P ++A + E+ RL P+ PF R LD +G + +P G
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKG 412
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 68.9 bits (161), Expect = 1e-11
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L + + D KA + + + G++T + +L + LY ++ Q + +E+
Sbjct: 304 RLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQA 363
Query: 186 SEDLAG----APSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D+A P ++A+I E RL P + L R L + + + + IP T V A
Sbjct: 364 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 423
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F+ E + P RW+ + Y FG G R C G+R ELE+ + L
Sbjct: 424 REPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFL 476
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 68.9 bits (161), Expect = 1e-11
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L + + D KA + + + G++T + +L + LY ++ Q + +E+
Sbjct: 22 RLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQA 81
Query: 186 SEDLAG----APSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D+A P ++A+I E RL P + L R L + + + + IP T V A
Sbjct: 82 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 141
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F+ E + P RW+ + Y FG G R C G+R ELE+ + L
Sbjct: 142 REPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFL 194
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 68.9 bits (161), Expect = 1e-11
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L + + D KA + + + G++T + +L + LY ++ Q + +E+
Sbjct: 304 RLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQA 363
Query: 186 SEDLAG----APSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D+A P ++A+I E RL P + L R L + + + + IP T V A
Sbjct: 364 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 423
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F+ E + P RW+ + Y FG G R C G+R ELE+ + L
Sbjct: 424 REPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFL 476
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 68.9 bits (161), Expect = 1e-11
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = +3
Query: 6 KILENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLC 185
++L + + D KA + + + G++T + +L + LY ++ Q + +E+
Sbjct: 304 RLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQA 363
Query: 186 SEDLAG----APSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D+A P ++A+I E RL P + L R L + + + + IP T V A
Sbjct: 364 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 423
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLL 512
R F+ E + P RW+ + Y FG G R C G+R ELE+ + L
Sbjct: 424 REPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFL 476
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 67.3 bits (157), Expect = 3e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPSRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 67.3 bits (157), Expect = 3e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPSRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 66.5 bits (155), Expect = 5e-11
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 6/160 (3%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRAAI 227
D AG +T NSL++ L +S PD Q K++ E+ D A P A I
Sbjct: 348 DLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATI 407
Query: 228 NEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAEEYLPERW 404
E RL P + S T+ G+ IP GT +L + + R + + E++ P R+
Sbjct: 408 MEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRF 467
Query: 405 IKVQ-EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ Q + PFG G+R+C G++ ++EL L+ +
Sbjct: 468 LDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSL 507
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 66.5 bits (155), Expect = 5e-11
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 6/160 (3%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRAAI 227
D AG +T NSL++ L +S PD Q K++ E+ D A P A I
Sbjct: 348 DLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATI 407
Query: 228 NEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAEEYLPERW 404
E RL P + S T+ G+ IP GT +L + + R + + E++ P R+
Sbjct: 408 MEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRF 467
Query: 405 IKVQ-EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ Q + PFG G+R+C G++ ++EL L+ +
Sbjct: 468 LDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSL 507
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 66.5 bits (155), Expect = 5e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 66.1 bits (154), Expect = 7e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 66.1 bits (154), Expect = 7e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 66.1 bits (154), Expect = 7e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 66.1 bits (154), Expect = 7e-11
Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F EL + A
Sbjct: 420 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNELKVATA 472
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.1 bits (154), Expect = 7e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPENFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 271 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 329
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 330 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 388
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 389 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 429
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAEDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.7 bits (153), Expect = 9e-11
Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 65.3 bits (152), Expect = 1e-10
Identities = 50/169 (29%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 301 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 360
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 361 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 420
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELEL 500
+ + E + P R+ H+++ + PF G R C GK+F EL
Sbjct: 421 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNEL 468
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 64.9 bits (151), Expect = 2e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 179 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 238
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 239 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 297
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 298 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 348
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 64.9 bits (151), Expect = 2e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 458
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 64.9 bits (151), Expect = 2e-10
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + E L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F +L + A
Sbjct: 420 HNPKVWPNPEVFDPSRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNQLKVARA 472
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 64.9 bits (151), Expect = 2e-10
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + E L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F +L + A
Sbjct: 420 HNPKVWPNLEVFDPSRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNQLKVARA 472
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 64.9 bits (151), Expect = 2e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 458
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 64.9 bits (151), Expect = 2e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 458
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 64.9 bits (151), Expect = 2e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 458
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 64.9 bits (151), Expect = 2e-10
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + E L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F +L + A
Sbjct: 420 HNPKVWPNLEVFDPSRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNQLKVARA 472
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 64.9 bits (151), Expect = 2e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 458
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 64.5 bits (150), Expect = 2e-10
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
Frame = +3
Query: 12 LENPA-LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRK----INSELPPYA 176
+EN + L +D +A + F+ G +T A+ + ++LY L+ P Q + I+S L A
Sbjct: 300 MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA 359
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ L P I EA RL P P + R L +P+T G +P G VL
Sbjct: 360 SITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLH 419
Query: 354 RREENFWRAEEYLPERWIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + E + P R+ H+++ + PF G R C GK+F +L + A
Sbjct: 420 HNPKVWPNPEVFDPFRFAPGSAQHSHAFL-PFSGGSRNCIGKQFAMNQLKVARA 472
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 2e-10
Identities = 49/161 (30%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F Y+L+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYVLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.1 bits (149), Expect = 3e-10
Identities = 49/161 (30%), Positives = 71/161 (44%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 339 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 397
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + + + PER
Sbjct: 398 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPKTFNPER 456
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G R LE+ L L +
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV 497
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 63.7 bits (148), Expect = 4e-10
Identities = 49/161 (30%), Positives = 70/161 (43%), Gaps = 8/161 (4%)
Frame = +3
Query: 63 FITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY------AMLCSEDLAGAPSVRAA 224
F+ AG E + N+L F YLL+ PD Q K+ E+ + CS + G P +
Sbjct: 338 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLE-EGLPYLDMV 396
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRA-EEYLPER 401
I E R+ P A R + G +IP G VL A + W + E + PER
Sbjct: 397 IAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA-VLEMAVGALHHDPEHWPSPETFNPER 455
Query: 402 W-IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ + ++ H PFG G R C G LE+ L L +
Sbjct: 456 FTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHV 496
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 63.3 bits (147), Expect = 5e-10
Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 4/159 (2%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+ F AG ET AN L F + LS +P+ ++ +E+ L EDL +
Sbjct: 297 VTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQV 356
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPERW 404
+ E+ RL P A RLL+ I G ++P T +L T R + F + P+R+
Sbjct: 357 LKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRF 416
Query: 405 IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P PF G R C G++F ++E+ +++AK+
Sbjct: 417 -GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKL 454
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 63.3 bits (147), Expect = 5e-10
Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 4/159 (2%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+ F AG ET AN L F + LS +P+ ++ +E+ L EDL +
Sbjct: 297 VTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQV 356
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPERW 404
+ E+ RL P A RLL+ I G ++P T +L T R + F + P+R+
Sbjct: 357 LKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRF 416
Query: 405 IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P PF G R C G++F ++E+ +++AK+
Sbjct: 417 -GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKL 454
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 62.1 bits (144), Expect = 1e-09
Identities = 43/161 (26%), Positives = 67/161 (41%), Gaps = 5/161 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSV 215
A +D + AG ET + +L + L+ PD Q ++ EL P ED P
Sbjct: 288 ACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLEDQQALPYT 347
Query: 216 RAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
A ++E R + P + R + +GG +P GT V+ + E + ++ P
Sbjct: 348 SAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNP 407
Query: 396 ERWIKVQEPHAY-SLVAPFGRGRRMCPGKRFVELELHLLLA 515
++ PF GRR+C G+R EL LL A
Sbjct: 408 GHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFA 448
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 62.1 bits (144), Expect = 1e-09
Identities = 48/172 (27%), Positives = 74/172 (43%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSL--VAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PE + + L PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 459
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 62.1 bits (144), Expect = 1e-09
Identities = 48/172 (27%), Positives = 74/172 (43%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E LP A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEPHAYSL--VAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PE + + L PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 459
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 61.7 bits (143), Expect = 2e-09
Identities = 48/172 (27%), Positives = 76/172 (44%), Gaps = 7/172 (4%)
Frame = +3
Query: 24 ALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY----AMLCSE 191
AL + A I I A +T + +L F++Y L+ PD Q+K+ E+ A + +
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPVTYD 348
Query: 192 DLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENF 371
L + +NE RL P + R+ + I G IP G V+ A + +
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMV-PIYALHHDPKY 407
Query: 372 W-RAEEYLPERWIKVQEP--HAYSLVAPFGRGRRMCPGKRFVELELHLLLAK 518
W E++ PER+ K + Y + PFG G R C G RF + L + +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYI-PFGAGPRNCIGMRFALTNIKLAVIR 458
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 60.5 bits (140), Expect = 3e-09
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY----AMLCSEDLAGA 206
D +A + F+ AG +T ++++ ++LY L+ P+ Q++ E+ + + E L+
Sbjct: 303 DLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQM 362
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWR-A 380
P I E RL ++RLLD P+T G +P G V + A FW
Sbjct: 363 PYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFIN-IWALHHNPYFWEDP 421
Query: 381 EEYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + P R+ + ++ H Y+ + PF G R C G+ F +E + +A
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFI-PFSAGLRNCIGQHFAIIECKVAVA 467
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 60.5 bits (140), Expect = 3e-09
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY----AMLCSEDLAGA 206
D +A + F+ AG +T ++++ ++LY L+ P+ Q++ E+ + + E L+
Sbjct: 303 DLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQM 362
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWR-A 380
P I E RL ++RLLD P+T G +P G V + A FW
Sbjct: 363 PYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFIN-IWALHHNPYFWEDP 421
Query: 381 EEYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + P R+ + ++ H Y+ + PF G R C G+ F +E + +A
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFI-PFSAGLRNCIGQHFAIIECKVAVA 467
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 60.5 bits (140), Expect = 3e-09
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY----AMLCSEDLAGA 206
D +A + F+ AG +T ++++ ++LY L+ P+ Q++ E+ + + E L+
Sbjct: 303 DLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQM 362
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWR-A 380
P I E RL ++RLLD P+T G +P G V + A FW
Sbjct: 363 PYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFIN-IWALHHNPYFWEDP 421
Query: 381 EEYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + P R+ + ++ H Y+ + PF G R C G+ F +E + +A
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFI-PFSAGLRNCIGQHFAIIECKVAVA 467
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 60.5 bits (140), Expect = 3e-09
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPY----AMLCSEDLAGA 206
D +A + F+ AG +T ++++ ++LY L+ P+ Q++ E+ + + E L+
Sbjct: 303 DLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQM 362
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWR-A 380
P I E RL ++RLLD P+T G +P G V + A FW
Sbjct: 363 PYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFIN-IWALHHNPYFWEDP 421
Query: 381 EEYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ + P R+ + ++ H Y+ + PF G R C G+ F +E + +A
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFI-PFSAGLRNCIGQHFAIIECKVAVA 467
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 288 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 347
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 348 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 407
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 408 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 463
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 234 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 293
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 294 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 353
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 354 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 409
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 234 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 293
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 294 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 353
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 354 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 409
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 59.7 bits (138), Expect = 6e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 234 NPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 293
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 294 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 353
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 354 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 409
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 59.7 bits (138), Expect = 6e-09
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 262 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 321
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 322 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 381
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 382 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 423
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 288 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 347
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 348 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 407
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 408 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 463
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 161 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 220
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 221 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 280
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 281 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 336
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 284 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 343
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 344 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 403
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 404 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 459
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 59.3 bits (137), Expect = 8e-09
Identities = 43/162 (26%), Positives = 70/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
+ E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ +EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAI 454
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 460
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 59.3 bits (137), Expect = 8e-09
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCS------ 188
LDM+ K + + + G ET A++ L+ L P +K+ EL +LC
Sbjct: 216 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNK 275
Query: 189 ---EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
E L + I E RL P P R+ + G++IP G V+
Sbjct: 276 LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDV 335
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E F EE+ P+R++ ++ +S + PFG G R C GK F ++ L + ++
Sbjct: 336 AEIFTNKEEFNPDRFMLPHPEDASRFSFI-PFGGGLRSCVGKEFAKILLKIFTVEL 390
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCS------ 188
LDM+ K + + + G ET A++ L+ L P +K+ EL +LC
Sbjct: 285 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNK 344
Query: 189 ---EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
E L + I E RL P P R+ + G++IP G V+
Sbjct: 345 LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDV 404
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E F EE+ P+R++ ++ +S + PFG G R C GK F ++ L + ++
Sbjct: 405 AEIFTNKEEFNPDRFMLPHPEDASRFSFI-PFGGGLRSCVGKEFAKILLKIFTVEL 459
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 59.3 bits (137), Expect = 8e-09
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCS------ 188
LDM+ K + + + G ET A++ L+ L P +K+ EL +LC
Sbjct: 285 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNK 344
Query: 189 ---EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRR 359
E L + I E RL P P R+ + G++IP G V+
Sbjct: 345 LDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDV 404
Query: 360 EENFWRAEEYLPERWI--KVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E F EE+ P+R++ ++ +S + PFG G R C GK F ++ L + ++
Sbjct: 405 AEIFTNKEEFNPDRFMLPHPEDASRFSFI-PFGGGLRSCVGKEFAKILLKIFTVEL 459
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 59.3 bits (137), Expect = 8e-09
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Frame = +3
Query: 18 NPALDMRDKKAAII--DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCSE 191
NP D+ I+ D +AG+ T + +L + L L+ PD QR++ E+
Sbjct: 354 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 413
Query: 192 ----DLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACR 356
D A P A I+E R P + + + + G +IP GT ++ + ++ +
Sbjct: 414 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 473
Query: 357 REENFWRAEEYLPERWIKVQ----EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
E + + + PE ++ Q +P A+ PF GRR C G+ +EL L +
Sbjct: 474 DEAVWEKPFRFHPEHFLDAQGHFVKPEAF---LPFSAGRRACLGEPLARMELFLFFTSL 529
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 58.4 bits (135), Expect = 1e-08
Identities = 43/162 (26%), Positives = 70/162 (43%), Gaps = 6/162 (3%)
Frame = +3
Query: 54 IIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRA 221
+ D AG ET + +L + L +L P+ + K++ E+ P + +D P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 222 AINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPE 398
++E R + P L G+ IP GT V+ + + F E++ PE
Sbjct: 353 VVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPE 412
Query: 399 RWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ YS PF G+R+C G+ EL LLL I
Sbjct: 413 HFLNENGKFKYSDYFKPFSTGKRVCAGEGLARTELFLLLCAI 454
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 365 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 424
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 425 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 471
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 365 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 424
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 425 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 471
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 365 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 424
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 425 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 471
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 365 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 424
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 425 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 471
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 304 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 364 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 423
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 424 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 470
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 365 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 424
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 425 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 471
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 58.0 bits (134), Expect = 2e-08
Identities = 45/168 (26%), Positives = 76/168 (45%), Gaps = 7/168 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D + + F+ AG +TLA S+ ++LY L+ P+ Q + E L + + + L
Sbjct: 240 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 299
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREENFWRAE 383
I E RL+P P ++R L P+T G +P G V+ + +
Sbjct: 300 SYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPK 359
Query: 384 EYLPERWIK--VQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ P R+ + + H Y+ + PF G R C G+ F +EL + +A I
Sbjct: 360 VFDPLRFSQENSDQRHPYAYL-PFSAGSRNCIGQEFAMIELKVTIALI 406
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 58.0 bits (134), Expect = 2e-08
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAEEYLPER 401
+NE RL P A L R + I G IP G+ V+ T A + +W EE+ PER
Sbjct: 31 VNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYAL-HHDPKYWTEPEEFRPER 89
Query: 402 WIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ K ++ + PFG G R C G RF + + L L ++
Sbjct: 90 FSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 129
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 58.0 bits (134), Expect = 2e-08
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 225 INEAFRLLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFW-RAEEYLPER 401
+NE RL P A L R + I G IP G+ V+ T A + +W EE+ PER
Sbjct: 18 VNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYAL-HHDPKYWTEPEEFRPER 76
Query: 402 WIKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
+ K ++ + PFG G R C G RF + + L L ++
Sbjct: 77 FSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 116
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 57.2 bits (132), Expect = 3e-08
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM----- 179
+ AL D +A F+ G +T A+ L ++LY L+ P++Q + E+
Sbjct: 309 DGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPK 368
Query: 180 -LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ +DLA P + + E+ RL P APF++R + + G IP G L
Sbjct: 369 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVH 428
Query: 354 RREENFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ K + P A+ PF G R C G+ F E+ ++LA
Sbjct: 429 HNPTVWPDPEVYDPFRFDPENSKGRSPLAF---IPFSAGPRNCIGQAFAMAEMKVVLA 483
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 57.2 bits (132), Expect = 3e-08
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM----- 179
+ AL D +A F+ G +T A+ L ++LY L+ P++Q + E+
Sbjct: 309 DGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPK 368
Query: 180 -LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ +DLA P + + E+ RL P APF++R + + G IP G L
Sbjct: 369 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVH 428
Query: 354 RREENFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ K + P A+ PF G R C G+ F E+ ++LA
Sbjct: 429 HNPTVWPDPEVYDPFRFDPENSKGRSPLAF---IPFSAGPRNCIGQAFAMAEMKVVLA 483
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 57.2 bits (132), Expect = 3e-08
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM----- 179
+ AL D +A F+ G +T A+ L ++LY L+ P++Q + E+
Sbjct: 309 DGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPK 368
Query: 180 -LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ +DLA P + + E+ RL P APF++R + + G IP G L
Sbjct: 369 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVH 428
Query: 354 RREENFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ K + P A+ PF G R C G+ F E+ ++LA
Sbjct: 429 HNPTVWPDPEVYDPFRFDPENSKGRSPLAF---IPFSAGPRNCIGQAFAMAEMKVVLA 483
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 57.2 bits (132), Expect = 3e-08
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM----- 179
+ AL D +A F+ G +T A+ L ++LY L+ P++Q + E+
Sbjct: 243 DGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPK 302
Query: 180 -LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ +DLA P + + E+ RL P APF++R + + G IP G L
Sbjct: 303 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVH 362
Query: 354 RREENFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ K + P A+ PF G R C G+ F E+ ++LA
Sbjct: 363 HNPTVWPDPEVYDPFRFDPENSKGRSPLAF---IPFSAGPRNCIGQAFAMAEMKVVLA 417
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 57.2 bits (132), Expect = 3e-08
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM----- 179
+ AL D +A F+ G +T A+ L ++LY L+ P++Q + E+
Sbjct: 309 DGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPK 368
Query: 180 -LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ +DLA P + + E+ RL P APF++R + + G IP G L
Sbjct: 369 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVH 428
Query: 354 RREENFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ K + P A+ PF G R C G+ F E+ ++LA
Sbjct: 429 HNPTVWPDPEVYDPFRFDPENSKGRSPLAF---IPFSAGPRNCIGQAFAMAEMKVVLA 483
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 57.2 bits (132), Expect = 3e-08
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Frame = +3
Query: 15 ENPALDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM----- 179
+ AL D +A F+ G +T A+ L ++LY L+ P++Q + E+
Sbjct: 309 DGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPK 368
Query: 180 -LCSEDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAAC 353
+ +DLA P + + E+ RL P APF++R + + G IP G L
Sbjct: 369 EIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVH 428
Query: 354 RREENFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ K + P A+ PF G R C G+ F E+ ++LA
Sbjct: 429 HNPTVWPDPEVYDPFRFDPENSKGRSPLAF---IPFSAGPRNCIGQAFAMAEMKVVLA 483
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 305 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 365 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 423
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 424 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 469
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 290 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 349
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 350 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 408
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 409 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 454
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 305 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 365 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 423
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 424 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 469
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 305 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 365 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 423
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 424 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 469
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 290 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 349
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 350 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 408
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 409 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 454
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 305 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 364
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 365 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 423
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 424 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 469
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 290 DLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 349
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 350 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 408
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 409 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 454
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 56.0 bits (129), Expect = 8e-08
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 55.6 bits (128), Expect = 1e-07
Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 8/177 (4%)
Frame = +3
Query: 15 ENPALDMRDKKA--AIIDFITAGIETLANSLVFLLYLLSGRPD---WQRK-INSELPPYA 176
+NP + +K +I + AG T++ ++ + L LL P W R+ +N EL
Sbjct: 281 QNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQ 340
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D P A ++EA RLL P + R L G+ +P GT V +
Sbjct: 341 APSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSIL 400
Query: 354 RREENFWRAEEYLPERWIKVQEP-HAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ P+R++ + PF G+R+C G+ + EL L I
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTI 457
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 55.6 bits (128), Expect = 1e-07
Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 8/177 (4%)
Frame = +3
Query: 15 ENPALDMRDKKA--AIIDFITAGIETLANSLVFLLYLLSGRPD---WQRK-INSELPPYA 176
+NP + +K +I + AG T++ ++ + L LL P W R+ +N EL
Sbjct: 281 QNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQ 340
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D P A ++EA RLL P + R L G+ +P GT V +
Sbjct: 341 APSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSIL 400
Query: 354 RREENFWRAEEYLPERWIKVQEP-HAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ P+R++ + PF G+R+C G+ + EL L I
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTI 457
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 55.6 bits (128), Expect = 1e-07
Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 8/167 (4%)
Frame = +3
Query: 39 DKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSE----LPPYAMLCSEDLAGA 206
D +A + F+ G +T + + LY ++ P+ Q + E L +DL
Sbjct: 304 DLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKM 363
Query: 207 PSVRAAINEAFRLLPTAPFLARLLDSPMT-IGGHKIPPGTFVLAHTAAACRREENFWRAE 383
+ I E+FRL P P + R L P+T + G +P G+ + H A R W
Sbjct: 364 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMH-IYALHRNSAVWPDP 422
Query: 384 EYLPERWIKVQ---EPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
E + + H ++ + PF G R C G++F E+ ++ A
Sbjct: 423 EVFDSLRFSTENASKRHPFAFM-PFSAGPRNCIGQQFAMSEMKVVTA 468
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 55.6 bits (128), Expect = 1e-07
Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 8/177 (4%)
Frame = +3
Query: 15 ENPALDMRDKKA--AIIDFITAGIETLANSLVFLLYLLSGRPD---WQRK-INSELPPYA 176
+NP + +K +I + AG T++ ++ + L LL P W R+ +N EL
Sbjct: 281 QNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQ 340
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D P A ++EA RLL P + R L G+ +P GT V +
Sbjct: 341 APSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSIL 400
Query: 354 RREENFWRAEEYLPERWIKVQEP-HAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ P+R++ + PF G+R+C G+ + EL L I
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTI 457
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 55.6 bits (128), Expect = 1e-07
Identities = 47/177 (26%), Positives = 74/177 (41%), Gaps = 8/177 (4%)
Frame = +3
Query: 15 ENPALDMRDKKA--AIIDFITAGIETLANSLVFLLYLLSGRPD---WQRK-INSELPPYA 176
+NP + +K +I + AG T++ ++ + L LL P W R+ +N EL
Sbjct: 281 QNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQ 340
Query: 177 MLCSEDLAGAPSVRAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAAC 353
D P A ++EA RLL P + R L G+ +P GT V +
Sbjct: 341 APSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSIL 400
Query: 354 RREENFWRAEEYLPERWIKVQEP-HAYSLVAPFGRGRRMCPGKRFVELELHLLLAKI 521
F EE+ P+R++ + PF G+R+C G+ + EL L I
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTI 457
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 54.8 bits (126), Expect = 2e-07
Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 287 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 346
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 347 VHEVQRCIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 404
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ + S PF G+R+C G+ +EL L L I
Sbjct: 405 HHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 447
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 54.8 bits (126), Expect = 2e-07
Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 287 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 346
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 347 VHEVQRCIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 404
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ + S PF G+R+C G+ +EL L L I
Sbjct: 405 HHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 447
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 54.8 bits (126), Expect = 2e-07
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRAAI 227
+ I AG ET N L + + ++ P+ Q ++ E+ P +D P A +
Sbjct: 306 ELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVL 365
Query: 228 NEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEE-YLPER 401
+E R P + + G+ IP GT V+ + + +E +WR E + PER
Sbjct: 366 HEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSV-HFDEKYWRDPEVFHPER 424
Query: 402 WIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ A + PF GRR C G+ +E+ L +
Sbjct: 425 FLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTAL 465
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 54.8 bits (126), Expect = 2e-07
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRAAI 227
+ I AG ET N L + + ++ P+ Q ++ E+ P +D P A +
Sbjct: 306 ELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVL 365
Query: 228 NEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEE-YLPER 401
+E R P + + G+ IP GT V+ + + +E +WR E + PER
Sbjct: 366 HEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSV-HFDEKYWRDPEVFHPER 424
Query: 402 WIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ A + PF GRR C G+ +E+ L +
Sbjct: 425 FLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTAL 465
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 54.8 bits (126), Expect = 2e-07
Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELP----PYAMLCSEDLAGAPSVRAAI 227
+ I AG ET N L + + ++ P+ Q ++ E+ P +D P A +
Sbjct: 306 ELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVL 365
Query: 228 NEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEE-YLPER 401
+E R P + + G+ IP GT V+ + + +E +WR E + PER
Sbjct: 366 HEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSV-HFDEKYWRDPEVFHPER 424
Query: 402 WIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ A + PF GRR C G+ +E+ L +
Sbjct: 425 FLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTAL 465
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 289 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 348
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 349 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 408
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 409 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 109 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 168
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 169 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 228
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 229 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 272
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 230 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 289
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 290 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 349
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 350 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 393
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 289 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 348
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 349 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 408
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 409 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 289 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 348
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 349 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 408
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 409 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 289 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 348
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 349 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 408
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 409 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 289 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 348
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 349 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 408
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 409 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 54.4 bits (125), Expect = 2e-07
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 289 ATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYT 348
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT ++ + ++ F E +
Sbjct: 349 DAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFD 408
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+RMC G+ +EL L L I
Sbjct: 409 PGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 54.0 bits (124), Expect = 3e-07
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 6/164 (3%)
Frame = +3
Query: 48 AAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSV 215
A + D AG ET + +L + L LL P+ K+ E+ C +D + P
Sbjct: 169 ATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRSHMPYT 228
Query: 216 RAAINEAFRLLPTAPF-LARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYL 392
A ++E R + P L + + + IP GT +L + + F E +
Sbjct: 229 DAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFD 288
Query: 393 PERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
P ++ S PF G+R+C G+ +EL L L I
Sbjct: 289 PRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 332
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 53.6 bits (123), Expect = 4e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 MWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 53.6 bits (123), Expect = 4e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 MWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 279 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 338
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 339 VHEVQRYIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 396
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 397 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 439
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 185 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 244
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 245 VHEVQRCIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 302
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 303 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 345
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 53.2 bits (122), Expect = 5e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 VWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 289 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 348
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 349 VHEVQRYIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 406
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 407 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 449
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 292 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 351
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 352 VHEVQRYIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 409
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 410 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 53.2 bits (122), Expect = 5e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 VWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 53.2 bits (122), Expect = 5e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 VWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 292 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 351
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 352 VHEVQRYIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 409
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 410 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 292 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 351
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 352 VHEVQRYIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 409
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 410 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 53.2 bits (122), Expect = 5e-07
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 8/163 (4%)
Frame = +3
Query: 57 IDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYA----MLCSEDLAGAPSVRAA 224
+D AG ET + +L + L LL P+ K+ E+ C +D + P A
Sbjct: 292 VDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAV 351
Query: 225 INEAFR---LLPTAPFLARLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLP 395
++E R LLPT+ L + + + IP GT +L + + F E + P
Sbjct: 352 VHEVQRYIDLLPTS--LPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDP 409
Query: 396 ERWIKVQEPHAYS-LVAPFGRGRRMCPGKRFVELELHLLLAKI 521
++ S PF G+R+C G+ +EL L L I
Sbjct: 410 HHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 53.2 bits (122), Expect = 5e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 VWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 53.2 bits (122), Expect = 5e-07
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Frame = +3
Query: 27 LDMRDKKAAIIDFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAM------LCS 188
L D +A F+ G +T A+ L ++LY L+ P++Q + E+ +
Sbjct: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
Query: 189 EDLAGAPSVRAAINEAFRLLPTAPFLARLLDSPMTI-GGHKIPPGTFVLAHTAAACRREE 365
+DLA P + + E+ RL P P ++R + + + G IP G L
Sbjct: 373 DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
Query: 366 NFWRAEEYLPERW----IKVQEPHAYSLVAPFGRGRRMCPGKRFVELELHLLLA 515
+ E Y P R+ IK + P A+ PF G R C G+ F E+ ++LA
Sbjct: 433 VWPDPEVYDPFRFDPENIKERSPLAF---IPFSAGPRNCIGQTFAMAEMKVVLA 483
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 52.8 bits (121), Expect = 7e-07
Identities = 42/160 (26%), Positives = 68/160 (42%), Gaps = 8/160 (5%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCS----EDLAGAPSVRAAI 227
D AG+ET + + + L L P ++K+ E+ D + A I
Sbjct: 298 DIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATI 357
Query: 228 NEAFRLLPTAPFLA-RLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPERW 404
E RL P AP L + +IG + GT V+ + A E+ + + ++++PER+
Sbjct: 358 REVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERF 417
Query: 405 IKVQEPHAYS---LVAPFGRGRRMCPGKRFVELELHLLLA 515
+ S PFG G R C G+ EL L++A
Sbjct: 418 LNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 52.8 bits (121), Expect = 7e-07
Identities = 42/160 (26%), Positives = 68/160 (42%), Gaps = 8/160 (5%)
Frame = +3
Query: 60 DFITAGIETLANSLVFLLYLLSGRPDWQRKINSELPPYAMLCS----EDLAGAPSVRAAI 227
D AG+ET + + + L L P ++K+ E+ D + A I
Sbjct: 298 DIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATI 357
Query: 228 NEAFRLLPTAPFLA-RLLDSPMTIGGHKIPPGTFVLAHTAAACRREENFWRAEEYLPERW 404
E RL P AP L + +IG + GT V+ + A E+ + + ++++PER+
Sbjct: 358 REVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERF 417
Query: 405 IKVQEPHAYS---LVAPFGRGRRMCPGKRFVELELHLLLA 515
+ S PFG G R C G+ EL L++A
Sbjct: 418 LNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,050,841
Number of Sequences: 237096
Number of extensions: 1859508
Number of successful extensions: 5288
Number of sequences better than 10.0: 420
Number of HSP's better than 10.0 without gapping: 4784
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5021
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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