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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ovS302D07f
         (521 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;...   205   4e-52
UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;...   199   3e-50
UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat...   173   2e-42
UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G...   167   2e-40
UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ...   156   3e-37
UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu...   145   6e-34
UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy...   142   6e-33
UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat...   138   5e-32
UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...   136   4e-31
UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat...   136   4e-31
UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep...   133   2e-30
UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase...   128   6e-29
UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   128   8e-29
UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ...   128   1e-28
UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola...   126   4e-28
UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000...   123   2e-27
UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve...   123   2e-27
UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur...   121   1e-26
UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot...   120   2e-26
UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   119   4e-26
UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...   118   1e-25
UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5; ...   116   2e-25
UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   116   4e-25
UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ...   115   6e-25
UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrola...   115   8e-25
UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl...   115   8e-25
UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ...   114   1e-24
UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,...   114   1e-24
UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ...   113   2e-24
UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl...   113   2e-24
UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola...   113   2e-24
UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat...   113   2e-24
UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re...   113   2e-24
UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...   113   2e-24
UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos...   113   2e-24
UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ...   113   3e-24
UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;...   113   3e-24
UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=1...   111   7e-24
UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...   111   7e-24
UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   111   9e-24
UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ...   111   9e-24
UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur...   111   1e-23
UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur...   110   2e-23
UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...   110   2e-23
UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   109   4e-23
UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat...   109   5e-23
UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ...   107   1e-22
UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot...   107   2e-22
UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; ...   107   2e-22
UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;...   106   3e-22
UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...   106   4e-22
UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat...   103   2e-21
UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola...   103   2e-21
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri...   101   1e-20
UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ...   101   1e-20
UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola...   101   1e-20
UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas...   101   1e-20
UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   101   1e-20
UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot...   101   1e-20
UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr...   100   2e-20
UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion...    99   3e-20
UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ...    99   3e-20
UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrola...    99   3e-20
UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrola...    99   7e-20
UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola...    98   9e-20
UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat...    98   1e-19
UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit...    98   1e-19
UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione ...    97   2e-19
UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    97   2e-19
UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    97   2e-19
UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox...    97   3e-19
UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox...    96   4e-19
UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; ...    96   4e-19
UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily hydr...    96   4e-19
UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrola...    96   4e-19
UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ...    96   5e-19
UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9; ...    95   1e-18
UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    93   5e-18
UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; ...    93   5e-18
UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    92   8e-18
UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrola...    90   2e-17
UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;...    89   6e-17
UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill...    76   2e-16
UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot...    87   2e-16
UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    87   2e-16
UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    87   3e-16
UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola...    85   7e-16
UniRef50_Q71KM2 Cluster: Glyoxalase II; n=8; Plasmodium|Rep: Gly...    85   9e-16
UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome sh...    85   1e-15
UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    82   7e-15
UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia gloss...    80   3e-14
UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrola...    79   5e-14
UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrola...    79   6e-14
UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat...    76   6e-13
UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc...    76   6e-13
UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola...    75   1e-12
UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrola...    73   4e-12
UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    73   4e-12
UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo...    72   9e-12
UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrola...    69   5e-11
UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    68   1e-10
UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    66   3e-10
UniRef50_Q24F45 Cluster: Hydroxyacylglutathione hydrolase, putat...    65   1e-09
UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    64   1e-09
UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    63   3e-09
UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh...    62   6e-09
UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    58   1e-07
UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprot...    52   1e-06
UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1...    43   4e-06
UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ...    52   6e-06
UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; ...    48   7e-06
UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|R...    44   1e-05
UniRef50_Q6MNF6 Cluster: Metallo-beta-lactamase superfamily prot...    51   1e-05
UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamil...    51   1e-05
UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily prot...    46   2e-05
UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acine...    50   4e-05
UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; ...    49   7e-05
UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    48   1e-04
UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus...    48   1e-04
UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organ...    46   1e-04
UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira...    48   1e-04
UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ...    44   2e-04
UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily prot...    46   2e-04
UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cy...    47   3e-04
UniRef50_A2FLV6 Cluster: Metallo-beta-lactamase superfamily prot...    39   3e-04
UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; ...    46   5e-04
UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Ac...    46   5e-04
UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1...    46   5e-04
UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaprot...    44   0.003
UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-P...    44   0.003
UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat...    43   0.004
UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; ...    43   0.005
UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Can...    43   0.005
UniRef50_A0BKZ2 Cluster: Chromosome undetermined scaffold_113, w...    43   0.005
UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular o...    42   0.006
UniRef50_A7CUG8 Cluster: Beta-lactamase domain protein; n=1; Opi...    37   0.008
UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione hydro...    40   0.008
UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Re...    40   0.008
UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; ...    38   0.008
UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    42   0.009
UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syn...    42   0.009
UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Vic...    39   0.011
UniRef50_Q59X44 Cluster: Putative uncharacterized protein; n=1; ...    42   0.011
UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba...    40   0.014
UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3; Deh...    38   0.023
UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; ...    40   0.026
UniRef50_A1ID45 Cluster: Beta-lactamase-like; n=3; Bacteria|Rep:...    40   0.026
UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n...    40   0.035
UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; ...    40   0.035
UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37; Actinomyceta...    40   0.035
UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium p...    40   0.035
UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter...    40   0.035
UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c...    40   0.035
UniRef50_Q5FRS6 Cluster: Metallo-beta-lactamase superfamily prot...    33   0.040
UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5; B...    34   0.040
UniRef50_Q9JIL1 Cluster: Rsp29-like protein; n=1; Mus musculus|R...    40   0.046
UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;...    40   0.046
UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein; ...    39   0.060
UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; ...    39   0.060
UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1; A...    36   0.068
UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Re...    37   0.069
UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; She...    39   0.080
UniRef50_A4AWZ7 Cluster: Putative uncharacterized protein; n=2; ...    39   0.080
UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    38   0.11 
UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; ...    38   0.11 
UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo...    38   0.11 
UniRef50_A3SZ22 Cluster: Beta-lactamase-like; n=6; Proteobacteri...    38   0.11 
UniRef50_A0NAW9 Cluster: ENSANGP00000031703; n=1; Anopheles gamb...    38   0.11 
UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bac...    34   0.12 
UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; ...    38   0.14 
UniRef50_A2QJI7 Cluster: Catalytic activity:; n=3; Aspergillus|R...    38   0.14 
UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4; Deino...    38   0.18 
UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ...    38   0.18 
UniRef50_A3L9H1 Cluster: Putative uncharacterized protein; n=1; ...    38   0.18 
UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;...    35   0.20 
UniRef50_Q031I9 Cluster: Zn-dependent hydrolase, including glyox...    32   0.20 
UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clo...    36   0.20 
UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase, putat...    37   0.24 
UniRef50_Q4WA79 Cluster: Metallo-beta-lactamase domain protein, ...    37   0.32 
UniRef50_Q9PFB0 Cluster: Beta-lactamase hydrolase-like protein; ...    37   0.32 
UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium di...    35   0.34 
UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syn...    36   0.43 
UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep...    36   0.43 
UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bac...    31   0.44 
UniRef50_UPI000049880A Cluster: metallo-beta-lactamase superfami...    36   0.56 
UniRef50_Q1ZAD4 Cluster: Probable metallo-beta-lactamase superfa...    36   0.56 
UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; ...    36   0.56 
UniRef50_A6L981 Cluster: Metallo-beta-lactamase family protein; ...    36   0.56 
UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium c...    36   0.56 
UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lambl...    36   0.56 
UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bac...    36   0.56 
UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas s...    36   0.74 
UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clost...    36   0.74 
UniRef50_Q7RF44 Cluster: Putative uncharacterized protein PY0486...    36   0.74 
UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who...    36   0.74 
UniRef50_Q2UI96 Cluster: Zn-dependent hydrolases; n=4; Pezizomyc...    36   0.74 
UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; ...    35   0.98 
UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121; Proteobacte...    35   0.98 
UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo...    35   0.98 
UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syn...    35   0.98 
UniRef50_Q314Q9 Cluster: Metallo-beta-lactamase family protein; ...    30   0.98 
UniRef50_Q4JCD2 Cluster: Conserved protein; n=1; Sulfolobus acid...    31   1.3  
UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1; ...    35   1.3  
UniRef50_Q8REE5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    34   1.7  
UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyo...    34   1.7  
UniRef50_Q8NU87 Cluster: Zn-dependent hydrolases, including glyo...    34   1.7  
UniRef50_Q2W813 Cluster: Zn-dependent hydrolase; n=3; Magnetospi...    34   1.7  
UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-l...    34   1.7  
UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3; ...    34   1.7  
UniRef50_Q8Y5A2 Cluster: Lmo2167 protein; n=12; Listeria|Rep: Lm...    34   2.3  
UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor...    34   2.3  
UniRef50_A2DJY1 Cluster: Metallo-beta-lactamase superfamily prot...    34   2.3  
UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met...    29   2.9  
UniRef50_Q5H3M1 Cluster: Beta-lactamase; n=8; Xanthomonadaceae|R...    33   3.0  
UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalterom...    33   3.0  
UniRef50_A2FNK4 Cluster: Metallo-beta-lactamase superfamily prot...    33   3.0  
UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti...    31   3.7  
UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot...    33   4.0  
UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase fam...    33   4.0  
UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1; ...    33   4.0  
UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; ...    33   4.0  
UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2; Chloroflexus|...    33   4.0  
UniRef50_Q9RU26 Cluster: Peptide ABC transporter, permease prote...    33   5.2  
UniRef50_Q81LX4 Cluster: Metallo-beta-lactamase family protein; ...    33   5.2  
UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; ...    33   5.2  
UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein; ...    33   5.2  
UniRef50_Q9FJU6 Cluster: Arabidopsis thaliana genomic DNA, chrom...    33   5.2  
UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3; ...    33   5.2  
UniRef50_Q484V0 Cluster: Metallo-beta-lactamase family protein; ...    32   6.9  
UniRef50_Q47LT8 Cluster: Putative hydrolase; n=1; Thermobifida f...    32   6.9  
UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1; ...    32   6.9  
UniRef50_A0Z233 Cluster: Putative uncharacterized protein; n=3; ...    32   6.9  
UniRef50_Q59K47 Cluster: Putative uncharacterized protein; n=2; ...    32   6.9  
UniRef50_Q2U6W1 Cluster: Predicted protein; n=1; Aspergillus ory...    32   6.9  
UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosar...    32   6.9  
UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1; ...    32   9.2  
UniRef50_A3EQ47 Cluster: Zn-dependent hydrolase; n=1; Leptospiri...    32   9.2  
UniRef50_A0ZDI7 Cluster: TPR repeat protein; n=1; Nodularia spum...    32   9.2  
UniRef50_Q55BX0 Cluster: Putative uncharacterized protein; n=3; ...    32   9.2  

>UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus
           musculus (Mouse)
          Length = 260

 Score =  205 bits (501), Expect = 4e-52
 Identities = 88/144 (61%), Positives = 110/144 (76%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHICYFV+ P     S VFTGDTLF+ GCG+F+EGTAD+MYKAL+ +L  LP  TKV+CG
Sbjct: 113 GHICYFVSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCG 172

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT+ NLKFA HVEP N  ++ K++W++++   G+PTVPST+ EE  YNPFMRV E  V
Sbjct: 173 HEYTVNNLKFARHVEPGNAAIQEKLAWAKEKYAIGEPTVPSTLAEEFTYNPFMRVKEKTV 232

Query: 159 QNHTGKNDPIDTMKAIRLEKDTFK 88
           Q H G+ DP+ TM+AIR EKD FK
Sbjct: 233 QQHAGETDPVTTMRAIRREKDQFK 256


>UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo
           sapiens (Human)
          Length = 260

 Score =  199 bits (486), Expect = 3e-50
 Identities = 84/144 (58%), Positives = 109/144 (75%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHICYFV+ P       VFTGDTLF+ GCG+F+EGTAD+M KAL+ +L  LP  T+V+CG
Sbjct: 113 GHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCG 172

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT+ NLKFA HVEP N  ++ K++W++++ + G+PTVPST+ EE  YNPFMRV E  V
Sbjct: 173 HEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTV 232

Query: 159 QNHTGKNDPIDTMKAIRLEKDTFK 88
           Q H G+ DP+ TM+A+R EKD FK
Sbjct: 233 QQHAGETDPVTTMRAVRREKDQFK 256


>UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase,
           putative, expressed; n=3; Oryza sativa|Rep:
           Hydroxyacylglutathione hydrolase, putative, expressed -
           Oryza sativa subsp. japonica (Rice)
          Length = 258

 Score =  173 bits (421), Expect = 2e-42
 Identities = 79/144 (54%), Positives = 101/144 (70%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y+VT+ EE  D  VFTGDTLF+ GCGRFFEGTA+QMY++L   L SLP  T+V+CG
Sbjct: 115 GHISYYVTSKEE-EDPAVFTGDTLFIAGCGRFFEGTAEQMYQSLCVTLGSLPKPTQVYCG 173

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT++NLKF   VEP NE VK K+ W+Q +R   +PT+PSTIGEE   N FMRV    +
Sbjct: 174 HEYTVKNLKFILTVEPDNEKVKQKLEWAQKQREANQPTIPSTIGEEFETNTFMRVDLPEI 233

Query: 159 QNHTGKNDPIDTMKAIRLEKDTFK 88
           Q   G   P++ ++ +R  KD +K
Sbjct: 234 QAKFGAKSPVEALREVRKTKDNWK 257


>UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep:
           Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito)
          Length = 302

 Score =  167 bits (405), Expect = 2e-40
 Identities = 81/143 (56%), Positives = 101/143 (70%), Gaps = 1/143 (0%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HICY++  PE   D VVFTGDTLFL GCGRFFEGT  QMY ALIT LS+LPD TKV+CGH
Sbjct: 163 HICYYIETPE---DKVVFTGDTLFLAGCGRFFEGTPQQMYDALITKLSALPDDTKVYCGH 219

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQG-KPTVPSTIGEEKLYNPFMRVTELAV 160
           EY L NL+F   VEP N +    ++ +++   +G +  VPSTIG+EK  N FMRV E +V
Sbjct: 220 EYALNNLRFGNTVEPDNVDTLQLLNIAKESDLEGRRAMVPSTIGQEKRTNVFMRVHEASV 279

Query: 159 QNHTGKNDPIDTMKAIRLEKDTF 91
           Q   GK+ P++TM+A+R  KD F
Sbjct: 280 QKFVGKSTPLETMQALRAAKDKF 302


>UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 260

 Score =  156 bits (379), Expect = 3e-37
 Identities = 80/146 (54%), Positives = 95/146 (65%), Gaps = 3/146 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDS--VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVF 346
           GHICY +T P   + S  VVFTGDTLF+ GCGRFFEGTA QM  AL  IL +LP  T++F
Sbjct: 115 GHICYHITNPAADSTSPGVVFTGDTLFIAGCGRFFEGTAPQMDVALNEILKNLPVETQIF 174

Query: 345 CGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTEL 166
            GHEYT+ NLKFA HVEP NE    K+ W+Q +  QG  TVPST+ EEK  NPFMRV E 
Sbjct: 175 PGHEYTVANLKFACHVEPGNEKAAQKLEWAQRQIEQGGFTVPSTVAEEKATNPFMRVRES 234

Query: 165 -AVQNHTGKNDPIDTMKAIRLEKDTF 91
             +Q   G  D +  M  +R  K+ F
Sbjct: 235 EEIQKSIGTCDAVVGMAKLREMKNKF 260


>UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24;
           Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo
           sapiens (Human)
          Length = 291

 Score =  145 bits (351), Expect = 6e-34
 Identities = 73/153 (47%), Positives = 102/153 (66%), Gaps = 9/153 (5%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ YF+   +  +   +F+GD L + GCG   EG+A QMY++L   L +LP  TKVFCG
Sbjct: 113 GHMSYFLWEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAE-LGTLPPETKVFCG 171

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDR--RNQGK-------PTVPSTIGEEKLYNP 187
           HE+TL NL+FA  VEP N++V+AK+SW++ R    +GK       PTVPST+GEE+LYNP
Sbjct: 172 HEHTLSNLEFAQKVEPCNDHVRAKLSWAKARPLSRRGKRRDEDDVPTVPSTLGEERLYNP 231

Query: 186 FMRVTELAVQNHTGKNDPIDTMKAIRLEKDTFK 88
           F+RV E  V+  TGK  P D ++A+  E+  F+
Sbjct: 232 FLRVAEEPVRKFTGKAVPADVLEALCKERARFE 264


>UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20;
           Ascomycota|Rep: Function: RSP29 precursor - Aspergillus
           niger
          Length = 299

 Score =  142 bits (343), Expect = 6e-33
 Identities = 71/139 (51%), Positives = 95/139 (68%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHE 334
           ICYF+   ++G+D VVFTGDTLF+GGCGRFFEGTA +M+KAL   L++LPD TKV+ GHE
Sbjct: 166 ICYFM---QDGDDKVVFTGDTLFIGGCGRFFEGTAPEMHKALNETLAALPDDTKVYPGHE 222

Query: 333 YTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQN 154
           YT  N+KF   V  +    K +   + ++  QGK     TIG+EKL+N FMRV +  +Q 
Sbjct: 223 YTKGNVKFCLAVSQSEPIKKLEAFANANQETQGK----FTIGDEKLHNVFMRVNDPEIQK 278

Query: 153 HTGKNDPIDTMKAIRLEKD 97
            TGK DP++ M A+R  K+
Sbjct: 279 KTGKTDPVEVMAALREMKN 297


>UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione
           hydrolase, putative - Babesia bovis
          Length = 319

 Score =  138 bits (335), Expect = 5e-32
 Identities = 67/144 (46%), Positives = 93/144 (64%), Gaps = 1/144 (0%)
 Frame = -3

Query: 519 GHICYFVTAPEEGN-DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           GH+ Y+VT P +     ++FTGDT+F+GGCGRFFEGTAD M   + T+     D + ++C
Sbjct: 180 GHMLYYVTNPSDPTMQPLMFTGDTIFIGGCGRFFEGTADMMLNIMNTVRQYRKD-SLIYC 238

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
           GHEYT++NLKFA+ V+  +  VK K+ W++  R Q  PTVPST+GEE  YNPFMR   L 
Sbjct: 239 GHEYTVKNLKFASTVD-DSPAVKRKMEWAESARQQNLPTVPSTLGEELEYNPFMRTATL- 296

Query: 162 VQNHTGKNDPIDTMKAIRLEKDTF 91
             +  G+   +  M+ +R  KD F
Sbjct: 297 -MDKVGETTEVGAMRKLRQMKDRF 319


>UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Psychromonas|Rep: Hydroxyacylglutathione hydrolase -
           Psychromonas ingrahamii (strain 37)
          Length = 256

 Score =  136 bits (328), Expect = 4e-31
 Identities = 68/136 (50%), Positives = 90/136 (66%), Gaps = 6/136 (4%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAH 301
           ND ++F GDTLF GGCGR FEG+ +QM+KA ++ L+ LP++TKV+C HEYT  NL FA  
Sbjct: 122 NDELLFCGDTLFSGGCGRVFEGSFEQMFKA-VSRLALLPENTKVYCAHEYTQNNLIFAHQ 180

Query: 300 VEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV----QNHTGK--N 139
           +EP N+ +   I     +R QG+PT+PSTIG EK  NPF+R  +  V    Q+H GK  N
Sbjct: 181 IEPKNKALLNYIQQVSKKRQQGQPTIPSTIGLEKEINPFLRCQQQTVINKLQSHLGKELN 240

Query: 138 DPIDTMKAIRLEKDTF 91
           DP+    A+R  KD F
Sbjct: 241 DPLSCFSALRQYKDNF 256


>UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=2; Theileria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Theileria annulata
          Length = 362

 Score =  136 bits (328), Expect = 4e-31
 Identities = 69/144 (47%), Positives = 96/144 (66%), Gaps = 1/144 (0%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDS-VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           GHI Y+V  P   +   ++F+GDTLF+ GCGRFFEG A  M + + T+  SLP++T ++C
Sbjct: 223 GHIMYYVYHPSNDHQQPLLFSGDTLFISGCGRFFEGDARSMMEIVETV-KSLPENTLLYC 281

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
           GHEYTL+NL+FA  V+ ++   K K++WS++  ++G PTVPST+ EEKLYNPFMRV EL 
Sbjct: 282 GHEYTLKNLQFAYSVDKSDVVFK-KLNWSKETVSKGLPTVPSTLQEEKLYNPFMRVKEL- 339

Query: 162 VQNHTGKNDPIDTMKAIRLEKDTF 91
                 +     TM  +R  KD F
Sbjct: 340 -MKSLDEQSEESTMNKLRSLKDRF 362


>UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep:
           All0580 protein - Anabaena sp. (strain PCC 7120)
          Length = 257

 Score =  133 bits (322), Expect = 2e-30
 Identities = 65/142 (45%), Positives = 90/142 (63%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HI Y+     +     +F GDTLF GGCGR FEGT  QM ++L T L SLP++T+V+C H
Sbjct: 117 HIAYYFPPQTDDTPGELFCGDTLFAGGCGRLFEGTPAQMVESL-TKLRSLPENTRVWCAH 175

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
           EYTL+NL+FA  V+  N  ++ ++   + +R+QG  TVPS +G EKL NPF+R  + ++Q
Sbjct: 176 EYTLKNLQFALSVDSKNTELQKRLDEVKTKRSQGIATVPSLLGVEKLTNPFLRWEQPSLQ 235

Query: 156 NHTGKNDPIDTMKAIRLEKDTF 91
                NDP+ T   IR  KD F
Sbjct: 236 LAVNSNDPVQTFARIRGLKDKF 257


>UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase
           II, partial; n=1; Pan troglodytes|Rep: PREDICTED:
           similar to glyoxalase II, partial - Pan troglodytes
          Length = 284

 Score =  128 bits (310), Expect = 6e-29
 Identities = 52/89 (58%), Positives = 68/89 (76%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHICYFV+ P       VFTGDTLF+ GCG+F+EGTAD+M KAL+ +L  LP  T+V+CG
Sbjct: 56  GHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCG 115

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQ 253
           HEYT+ NLKFA HVEP N  ++ K++W++
Sbjct: 116 HEYTINNLKFARHVEPGNAAIREKLAWAK 144


>UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
           hydrolase - Dictyostelium discoideum AX4
          Length = 268

 Score =  128 bits (309), Expect = 8e-29
 Identities = 69/153 (45%), Positives = 92/153 (60%), Gaps = 11/153 (7%)
 Frame = -3

Query: 516 HICYFVTAPEEGND-SVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           H+ Y +    E N    +FTGDTLF+GGCGR FEG  +QMY AL  ++  LPD+T V+ G
Sbjct: 116 HVLYLIEDENEPNQVKSLFTGDTLFIGGCGRLFEGNPEQMYNALYNVIGKLPDNTLVYVG 175

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQ--DRRNQGKPTVPSTIGEEKLYNPFMRVTEL 166
           HEYTL+NL+FA  +E  NEN +    + Q  ++   G+ TVPS+I +EKL NPFMR    
Sbjct: 176 HEYTLKNLEFAKTLESENENKELYNFYDQCKEKLANGEFTVPSSIAQEKLINPFMRCHLP 235

Query: 165 AVQNHTGKND--------PIDTMKAIRLEKDTF 91
           ++ NH  K +        PID +  IR  KD F
Sbjct: 236 SIYNHYLKENPNSINPPSPIDVLGFIRSLKDKF 268


>UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep:
           Glyoxalase II - Oryza sativa (Rice)
          Length = 336

 Score =  128 bits (308), Expect = 1e-28
 Identities = 65/146 (44%), Positives = 89/146 (60%), Gaps = 3/146 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+CY    P  G    +FTGDTLF   CG+ FEGT  QMY +L  I++ LPD T+V+CG
Sbjct: 197 GHVCYHF--PGSG---AIFTGDTLFSLSCGKLFEGTPQQMYSSLQKIIA-LPDETRVYCG 250

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL N KFA  +EP N++++   + + D R +  PTVP+TIG EK  NPF+R +   +
Sbjct: 251 HEYTLSNSKFALSIEPGNKDLQEYAANAADLRKRNTPTVPTTIGREKQCNPFLRTSSPEI 310

Query: 159 QNHTGKNDPID---TMKAIRLEKDTF 91
           +N     D  D    ++ +R  KD F
Sbjct: 311 KNTLSIPDHFDDARVLEVVRRAKDNF 336


>UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=13; Bacteria|Rep: Probable hydroxyacylglutathione
           hydrolase - Synechocystis sp. (strain PCC 6803)
          Length = 257

 Score =  126 bits (303), Expect = 4e-28
 Identities = 64/144 (44%), Positives = 87/144 (60%), Gaps = 1/144 (0%)
 Frame = -3

Query: 519 GHICYFVTAPEEGND-SVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           GHI Y+  AP  G     +F GDT+F GGCGR FEGT  QM ++ I  L  LPD T+++C
Sbjct: 116 GHIAYYF-APGSGETIGDLFCGDTIFAGGCGRLFEGTPAQMVQS-IGKLRQLPDQTRLWC 173

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
            HEYTL NLKFA  V+P+N++++ +    Q  R +G+ T+PS +G EK  NPF+R    A
Sbjct: 174 AHEYTLGNLKFALTVDPSNKDLQERFQTVQGDRQRGQATIPSWLGTEKRTNPFLRWDNPA 233

Query: 162 VQNHTGKNDPIDTMKAIRLEKDTF 91
           +Q   G  +P      +R  KD F
Sbjct: 234 IQARVGMTEPARVFGKLRGMKDNF 257


>UniRef50_UPI0000DAE586 Cluster: hypothetical protein
           Rgryl_01000658; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000658 - Rickettsiella
           grylli
          Length = 257

 Score =  123 bits (297), Expect = 2e-27
 Identities = 64/150 (42%), Positives = 91/150 (60%), Gaps = 6/150 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y+      GN  ++F GDTLF  GCGR FEGT DQM  +L   L+ LPD T+++CG
Sbjct: 116 GHIAYY------GNH-LLFCGDTLFTAGCGRLFEGTPDQMLNSLEK-LAQLPDETQIYCG 167

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVT---- 172
           HEYTL NL FA  +EP N ++K ++  +++ R +  P VPS + EE+L NPF+R      
Sbjct: 168 HEYTLANLNFAQTIEPDNTHIKKRLEKTRELRQKNLPCVPSLLAEERLSNPFLRCNNPKI 227

Query: 171 ELAVQNHTGKN--DPIDTMKAIRLEKDTFK 88
           +  ++  TGK    P++    +R  K+ FK
Sbjct: 228 KKCIEKRTGKKLITPVEIFAYLRQWKNNFK 257


>UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 318

 Score =  123 bits (297), Expect = 2e-27
 Identities = 66/152 (43%), Positives = 94/152 (61%), Gaps = 8/152 (5%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y +      +   +F+GD LFLGGCGR FEG   +M ++L T+ SSL D T ++ G
Sbjct: 169 GHVVYLLHGAVFNSVDSLFSGDLLFLGGCGRIFEGAPGEMLESLQTV-SSLKDDTLLWPG 227

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           H+Y ++NL FA  +EP+N +++AK+ W  + RN    T PSTIGEEKLYNPF+R T LA+
Sbjct: 228 HDYAMKNLMFALTIEPSNYHLRAKMDWVVEMRNNKYMTSPSTIGEEKLYNPFLR-THLAI 286

Query: 159 ----QNHTGKND----PIDTMKAIRLEKDTFK 88
                  T  +D     +  +KA+R  K+ FK
Sbjct: 287 VGSAVGFTQDDDVNLRAVSVLKALRERKNNFK 318


>UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=44; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 269

 Score =  121 bits (291), Expect = 1e-26
 Identities = 66/152 (43%), Positives = 86/152 (56%), Gaps = 10/152 (6%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HI YF        + ++F GDTLF  GCGR FEGT  QM ++L    +SLP +T V+C H
Sbjct: 122 HIAYFANMQANVVEPMLFCGDTLFASGCGRLFEGTPTQMTQSLAKF-ASLPKNTLVYCTH 180

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDR---RNQGKPTVPSTIGEEKLYNPFMRVTEL 166
           EYTL N++FA  VEP N N+   ISW +     R+QG PT+P+T+G+E   NPFMR  + 
Sbjct: 181 EYTLSNIRFALAVEPNNVNL---ISWDEQARALRDQGLPTLPTTVGQELQVNPFMRCDQA 237

Query: 165 AV-------QNHTGKNDPIDTMKAIRLEKDTF 91
            V        NH   + P   +  IR  KD F
Sbjct: 238 EVIAAAKEISNHADLSTPAHVLAVIRAWKDRF 269


>UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Neptuniibacter caesariensis|Rep:
           Metallo-beta-lactamase superfamily protein -
           Neptuniibacter caesariensis
          Length = 257

 Score =  120 bits (289), Expect = 2e-26
 Identities = 57/114 (50%), Positives = 75/114 (65%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH    ++   E +   +F GDTLFL GCGR FEGTA QM  A+    +SLPD T+V+C 
Sbjct: 110 GHTLDHISYYSERHKPQLFCGDTLFLAGCGRLFEGTAKQMLNAM-NYFASLPDDTEVYCT 168

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEY++ NL FA  VEP N+ +K  I    ++R Q +PT+P++I EEKL NPFMR
Sbjct: 169 HEYSMANLSFAEAVEPNNDAIKNAIRRCAEQREQDQPTLPTSIAEEKLINPFMR 222


>UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep:
           Hydroxyacylglutathione hydrolase - Desulfuromonas
           acetoxidans DSM 684
          Length = 249

 Score =  119 bits (287), Expect = 4e-26
 Identities = 58/121 (47%), Positives = 80/121 (66%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           G  CY++   E      +F GDTLF GGCGR FEGT +Q+Y +L  I ++LP+ T+++CG
Sbjct: 111 GDCCYYLPQCE-----ALFCGDTLFSGGCGRVFEGTMEQLYHSLQKI-TALPETTRLYCG 164

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT +N +FAA +EP++  V  K+S     RN GKPT+P T+ EE L NPF+R  E  +
Sbjct: 165 HEYTEENYRFAASIEPSSATVHDKLSRVHYLRNHGKPTLPVTLAEELLCNPFLRCEEKEL 224

Query: 159 Q 157
           Q
Sbjct: 225 Q 225


>UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Marinobacter|Rep: Hydroxyacylglutathione hydrolase -
           Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 263

 Score =  118 bits (283), Expect = 1e-25
 Identities = 59/114 (51%), Positives = 79/114 (69%), Gaps = 1/114 (0%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDS-VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           HI Y+  +  + ND  V+F GDTLF+ GCGR FEGT +QM+ +L T L  LPD+T V+C 
Sbjct: 115 HIAYY--SDTQVNDKPVLFCGDTLFVCGCGRLFEGTPEQMHTSLQT-LRDLPDNTAVYCA 171

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEYTL NL+FA H  P ++ +    +  +D R +GKPTVP+TIG+EK  NPF+R
Sbjct: 172 HEYTLANLRFARHWLPEDKALAEFENACKDLRERGKPTVPTTIGQEKQLNPFLR 225


>UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5;
           Shewanella|Rep: Hydroxyacylglutathione hydrolase -
           Shewanella sp. (strain MR-4)
          Length = 295

 Score =  116 bits (280), Expect = 2e-25
 Identities = 58/114 (50%), Positives = 76/114 (66%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y V       D  +F GDTLF  GCGR FEG+  QM+++L ++L++LPD T+V+C 
Sbjct: 152 GHIAYLV-------DGALFCGDTLFSAGCGRLFEGSPAQMWQSL-SLLAALPDTTRVYCA 203

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEYTL NLKFA  V+  NE +KA +  + D R Q K T+PSTI  E+  NPF+R
Sbjct: 204 HEYTLANLKFAQAVDTDNEALKAYVKRTNDLRAQNKATIPSTIELERAINPFLR 257


>UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione
           hydrolase - Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score =  116 bits (278), Expect = 4e-25
 Identities = 63/140 (45%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHE 334
           IC++       N+  VFTGDTLF  GCGRFFEGTA +M+ AL  +LSSLP++T ++ GHE
Sbjct: 123 ICFYA---HSSNEHAVFTGDTLFNAGCGRFFEGTAAEMHIALNAVLSSLPNNTVIYPGHE 179

Query: 333 YTLQNLKFAA-HVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
           YT  N+KFA+ H++    N    +  + ++   G      T+G+EK +NPFMRVT+  +Q
Sbjct: 180 YTKSNVKFASKHLQSEALNHLEGLC-NHNQFIAGH----ITMGQEKQFNPFMRVTDPELQ 234

Query: 156 NHTGKNDPIDTMKAIRLEKD 97
            H G NDPI  M  +R  K+
Sbjct: 235 KHLGLNDPIKVMDELRTLKN 254


>UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein;
           n=14; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Shewanella oneidensis
          Length = 267

 Score =  115 bits (277), Expect = 6e-25
 Identities = 59/114 (51%), Positives = 73/114 (64%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y V       D  +F GDTLF GGCGR FEGT  QM  +L  +L++LP  T+V+C 
Sbjct: 124 GHIAYLV-------DGALFCGDTLFSGGCGRLFEGTPAQMCHSL-RLLAALPAETRVYCA 175

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEYTL NLKFA   +P+N  +KA    +   R QGK T+PSTIG E+  NPF+R
Sbjct: 176 HEYTLANLKFAQAADPSNAKLKAYNEQATALRAQGKATIPSTIGLERSINPFLR 229


>UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Oceanobacter sp. RED65|Rep: Probable
           hydroxyacylglutathione hydrolase - Oceanobacter sp.
           RED65
          Length = 264

 Score =  115 bits (276), Expect = 8e-25
 Identities = 63/150 (42%), Positives = 90/150 (60%), Gaps = 8/150 (5%)
 Frame = -3

Query: 516 HICYFV--TAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           HI ++   T PE  +   +F+GD +F  GCGR FEGTADQ Y++L +I++ LP  T ++C
Sbjct: 116 HIVFYTETTNPEGESQGHIFSGDNIFACGCGRMFEGTADQYYESLQSIVN-LPLDTIIYC 174

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE-- 169
            HEYTL N++FA HVEP N  +  +     D R++GKPT+P+T+ EE   NPF+R  +  
Sbjct: 175 THEYTLANIQFALHVEPNNTYILHRQDVCTDLRDKGKPTLPTTVVEELKSNPFVRCDQPD 234

Query: 168 --LAVQNHTGK--NDPIDTMKAIRLEKDTF 91
              A +  +G+    P D    IR  KD F
Sbjct: 235 VVRAAEQASGQVLAKPQDVFAVIRDMKDRF 264


>UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep:
           Glyoxalase IIB - Plasmodium falciparum
          Length = 263

 Score =  115 bits (276), Expect = 8e-25
 Identities = 62/149 (41%), Positives = 87/149 (58%), Gaps = 6/149 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDS------VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDH 358
           GHI Y+V   +E          ++FTGDTLF+ GCGRFFEG+A  M+K +  +  ++   
Sbjct: 118 GHILYYVYKTDEAKQEDHKYKPILFTGDTLFIAGCGRFFEGSAKDMFKNIEKV-KNMRKE 176

Query: 357 TKVFCGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           T ++CGHEYTL NL+FA  +E  NE +K K++   ++    + +VPSTI EE L NPF R
Sbjct: 177 TLIYCGHEYTLNNLRFALSIENDNEYMKNKLNEVTEKLKNKEHSVPSTIEEENLINPFFR 236

Query: 177 VTELAVQNHTGKNDPIDTMKAIRLEKDTF 91
            T   V N    ND I  +  +R  K+ F
Sbjct: 237 -THCYV-NKFNMNDEIKILDKLRQLKNNF 263


>UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas stutzeri (strain A1501)
          Length = 292

 Score =  114 bits (275), Expect = 1e-24
 Identities = 64/149 (42%), Positives = 89/149 (59%), Gaps = 6/149 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI YF   P++     + +GDTLF  GCGR FEGT +QM+++L T L+S PDHT V+C 
Sbjct: 148 GHIAYFHADPDQ---PWLLSGDTLFAAGCGRLFEGTPEQMFESL-TRLASAPDHTLVYCT 203

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL NL+FA  VEP N ++ A+I      R  G+ ++PS +  E+  NPF+R    AV
Sbjct: 204 HEYTLSNLRFAQAVEPHNADIAARIGEVTQLREAGRFSLPSRLDIERKTNPFLRSEVEAV 263

Query: 159 QNHTGKN--DPIDT----MKAIRLEKDTF 91
           +    ++   P+ T      A+R  KD F
Sbjct: 264 RQAASQHCGSPLATNVAVFAALRAWKDRF 292


>UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,
           partial; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 268

 Score =  114 bits (274), Expect = 1e-24
 Identities = 52/117 (44%), Positives = 78/117 (66%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y +   ++   + +FTGD LFLGG GR FEG    M  +L  I   +PD T V+ G
Sbjct: 114 GHMVYLLDRSDKNLPNSLFTGDILFLGGNGRMFEGPPSLMLSSLDKICQ-IPDDTLVWPG 172

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE 169
           HEY + NL+FA +++P NE+V  K+++ ++RR + + T PST+GEEK YNPF+R ++
Sbjct: 173 HEYAVDNLRFAHNIDPANEDVTRKLNYVEERRKERRITSPSTLGEEKSYNPFLRTSQ 229


>UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein;
           n=2; Alteromonadales|Rep: Metallo-beta-lactamase family
           protein - Colwellia psychrerythraea (strain 34H / ATCC
           BAA-681) (Vibriopsychroerythus)
          Length = 265

 Score =  113 bits (273), Expect = 2e-24
 Identities = 65/149 (43%), Positives = 85/149 (57%), Gaps = 6/149 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y+       ND +VF GDTLF GGCGR FEGT  QM+ +L T L++L   T ++C 
Sbjct: 125 GHIAYY-------NDKMVFCGDTLFSGGCGRLFEGTPQQMHHSL-TKLANLATDTLIYCA 176

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE--- 169
           HEYT  NL FA  VEP N ++       + +R Q + T+P+ I  E   NPF+R  E   
Sbjct: 177 HEYTQANLAFALAVEPNNTDLHNYAEQVKVKRQQNQATIPTNIALELQINPFLRCHEESI 236

Query: 168 -LAVQNHTGKNDPIDT--MKAIRLEKDTF 91
            LA Q ++ +N P D+    AIR  KD F
Sbjct: 237 KLAAQTYSNQNQPNDSEVFSAIRAWKDNF 265


>UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase
           cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep:
           Hydroxyacylglutathione hydrolase cytoplasmic -
           Candidatus Pelagibacter ubique HTCC1002
          Length = 239

 Score =  113 bits (273), Expect = 2e-24
 Identities = 56/114 (49%), Positives = 73/114 (64%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHIC++       N+  VFTGDTLF  GCG+ FEGT  QMY +L+ I  +LP+ TK++CG
Sbjct: 115 GHICFYFY-----NEESVFTGDTLFSLGCGKIFEGTYSQMYNSLMKI-KALPEKTKIYCG 168

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEYT QN KF    +  NEN+K KI    ++  +  PT+PSTI EE   N F+R
Sbjct: 169 HEYTKQNSKFCIAHDQDNENLKVKIKLIDEKLEKNLPTIPSTIKEELECNIFLR 222


>UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase
           with metallo- hydrolase/oxidoreductase domain; n=4;
           Proteobacteria|Rep: Putative hydroxyacylglutathione
           hydrolase with metallo- hydrolase/oxidoreductase domain
           - Pseudoalteromonas tunicata D2
          Length = 261

 Score =  113 bits (273), Expect = 2e-24
 Identities = 62/135 (45%), Positives = 80/135 (59%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HICY+     E     +F GDTLF GGCGR FEGTADQM+++++  LS LPD T V+C H
Sbjct: 120 HICYY-----EPQQDWLFCGDTLFSGGCGRLFEGTADQMFQSMVK-LSQLPDKTAVYCTH 173

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
           EYT  NL FA  +EP N ++          R   K ++PS+IG EK  NPFMR TE  + 
Sbjct: 174 EYTQSNLIFALVIEPQNLDLLQHHKKVDALRLANKASLPSSIGLEKKINPFMRSTEQHIT 233

Query: 156 NHTGKNDPIDTMKAI 112
            H     PI+  +A+
Sbjct: 234 EHV----PIEHQQAL 244


>UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Filobasidiella neoformans|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 274

 Score =  113 bits (273), Expect = 2e-24
 Identities = 61/139 (43%), Positives = 87/139 (62%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHE 334
           IC+F+   + G   V FTGDTLFL GCGRFFEGT ++M+ AL T LS+LP+ T V+ GHE
Sbjct: 139 ICFFLEDKKTGQRGV-FTGDTLFLAGCGRFFEGTPEEMHAAL-TKLSNLPEDTIVYNGHE 196

Query: 333 YTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQN 154
           YT  + KF   +EP N+++K  +  ++   N    T  STIG+EK +N FMR+     + 
Sbjct: 197 YTKGSAKFGLTIEPDNQHLKELLKKAE---NDSCTTGKSTIGDEKNWNVFMRLDTPQAKQ 253

Query: 153 HTGKNDPIDTMKAIRLEKD 97
            TGK + ++ M  +R  K+
Sbjct: 254 ATGKTEAVEIMGRLREMKN 272


>UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep:
           Isoform 3 of Q8N490 - Homo sapiens (Human)
          Length = 361

 Score =  113 bits (272), Expect = 2e-24
 Identities = 58/125 (46%), Positives = 76/125 (60%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y +        S +F+GD LFL GCGR FEG A+ M  +L T+L  L D T ++ G
Sbjct: 208 GHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLG-LGDDTLLWPG 266

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEY  +NL FA  VEP N   + K+ W Q +R + K T PST+GEE+ YNPF+R   LA+
Sbjct: 267 HEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLAL 326

Query: 159 QNHTG 145
           Q   G
Sbjct: 327 QEALG 331


>UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 282

 Score =  113 bits (272), Expect = 2e-24
 Identities = 63/139 (45%), Positives = 83/139 (59%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHE 334
           ICY+V   + G +  VFTGDTLF+ GCGRFFEGT  +M  AL  IL+ LP  TKV+ GHE
Sbjct: 147 ICYYVKDAKTG-EKAVFTGDTLFISGCGRFFEGTGAEMNVALNKILAKLPKDTKVYPGHE 205

Query: 333 YTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQN 154
           YT  N+KF+  +   NE +KA   ++Q   +    T   TIG+E  +NPFMR+ +  VQ 
Sbjct: 206 YTKSNVKFSKTI-LDNEAIKALDEYTQKHEH---TTGQFTIGDELNFNPFMRLLDPQVQE 261

Query: 153 HTGKNDPIDTMKAIRLEKD 97
            TG     D M  +R  K+
Sbjct: 262 KTGLTQADDVMTKLREMKN 280


>UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25;
           Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens
           (Human)
          Length = 385

 Score =  113 bits (272), Expect = 2e-24
 Identities = 58/125 (46%), Positives = 76/125 (60%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y +        S +F+GD LFL GCGR FEG A+ M  +L T+L  L D T ++ G
Sbjct: 232 GHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLG-LGDDTLLWPG 290

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEY  +NL FA  VEP N   + K+ W Q +R + K T PST+GEE+ YNPF+R   LA+
Sbjct: 291 HEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLAL 350

Query: 159 QNHTG 145
           Q   G
Sbjct: 351 QEALG 355


>UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=4; Legionella pneumophila|Rep: Hydroxyacylglutathione
           hydrolase GloB - Legionella pneumophila (strain Corby)
          Length = 254

 Score =  113 bits (271), Expect = 3e-24
 Identities = 64/149 (42%), Positives = 92/149 (61%), Gaps = 6/149 (4%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HI Y+   P++G    +F GDTLF  GCGR F+GT ++++++L+ +   LP +TKVFC H
Sbjct: 115 HISYY--EPQKG---WLFCGDTLFSAGCGRVFDGTIEELHESLL-LFKKLPRNTKVFCAH 168

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKP-TVPSTIGEEKLYNPFMR-----V 175
           EYTLQNLKFA  VEP N +V   I++ Q    Q  P T+PS I  E   NPF+R     V
Sbjct: 169 EYTLQNLKFAHTVEPCNSSV---INYMQQILKQPSPCTLPSNIDLELSINPFLRTDKEQV 225

Query: 174 TELAVQNHTGKNDPIDTMKAIRLEKDTFK 88
            + A+ +    +D +D  K +R +K++FK
Sbjct: 226 KQYALSHGANSSDSLDVFKVLRNQKNSFK 254


>UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;
           Ascomycota|Rep: Hydroxyacylglutathione hydrolase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score =  113 bits (271), Expect = 3e-24
 Identities = 62/135 (45%), Positives = 82/135 (60%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHE 334
           ICY+V++P +     VFTGDTLF  GCGRFFEG A QM  AL  +L++LPD T  + GHE
Sbjct: 123 ICYYVSSPSK---RAVFTGDTLFTSGCGRFFEGDAKQMDYALNHVLAALPDDTVTYPGHE 179

Query: 333 YTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQN 154
           YT  N KF++ +  T E  K  + +    +N    T   TIG+EK +NPFM +   +VQ 
Sbjct: 180 YTKSNAKFSSTIFSTPELTKL-VDFC---KNHESTTGHFTIGDEKKFNPFMCLGLESVQK 235

Query: 153 HTGKNDPIDTMKAIR 109
             G +DPI  MK +R
Sbjct: 236 AVGSSDPITVMKKLR 250


>UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=11;
           Proteobacteria|Rep: Metallo-beta-lactamase superfamily -
           Nitrosomonas europaea
          Length = 262

 Score =  111 bits (268), Expect = 7e-24
 Identities = 56/133 (42%), Positives = 81/133 (60%), Gaps = 6/133 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GDTLF  GCGR FEG A QM+ +L   L+ LPD T+V+C HEYTL N++FA  ++P 
Sbjct: 124 LFCGDTLFACGCGRIFEGNAQQMFDSLQK-LTDLPDETQVYCAHEYTLDNIRFARAIDPD 182

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV----QNHTGK--NDPID 127
           N  +    S  +++R Q  PT+PS++  EK  NPF+R  + A+      + G+   DP+ 
Sbjct: 183 NPELIELESNVEEKREQNMPTLPSSLAAEKATNPFLRCNQPAIIQSASRYAGRQLTDPVS 242

Query: 126 TMKAIRLEKDTFK 88
              AIR  K+ F+
Sbjct: 243 VFAAIRDWKNNFR 255


>UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Gammaproteobacteria|Rep: Hydroxyacylglutathione
           hydrolase - Halorhodospira halophila (strain DSM 244 /
           SL1) (Ectothiorhodospirahalophila (strain DSM 244 /
           SL1))
          Length = 255

 Score =  111 bits (268), Expect = 7e-24
 Identities = 65/148 (43%), Positives = 91/148 (61%), Gaps = 6/148 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y      EG+   +F+GD LF GGCGR FEGTA QM+ +L   L++LP  T+V CG
Sbjct: 115 GHIAYLW----EGH---LFSGDALFAGGCGRVFEGTAGQMHASL-QHLAALPADTRVCCG 166

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRV--TEL 166
           HEYT++NL+FA   +P N+ +  ++  ++D R  G+PTVPST+ EE   NPF+R    EL
Sbjct: 167 HEYTVKNLEFAHCADPKNDRLAQRLQAARDARAAGQPTVPSTLAEELATNPFLRTDCPEL 226

Query: 165 --AVQNHTGK--NDPIDTMKAIRLEKDT 94
             A Q+  G+  +   +    +R  KDT
Sbjct: 227 RRAAQDWCGRDLDQAYEVFATLRRWKDT 254


>UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione
           hydrolase - Magnetococcus sp. (strain MC-1)
          Length = 254

 Score =  111 bits (267), Expect = 9e-24
 Identities = 55/126 (43%), Positives = 76/126 (60%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+CY +          +F GDTLF  GCGR FEGT  QM+++L+ IL +LP+ T++ C 
Sbjct: 118 GHLCYHIA-------DCLFAGDTLFSYGCGRLFEGTPQQMWQSLL-ILRALPETTRLCCA 169

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL NL+FA  +    E + A    +Q  R  GKPT+PS + EEK YNPF+R  +   
Sbjct: 170 HEYTLTNLRFARSLPGQQEPLAAPWQRAQQTRQLGKPTLPSRLAEEKQYNPFLRCDDTQF 229

Query: 159 QNHTGK 142
           +   G+
Sbjct: 230 RTAVGQ 235


>UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 268

 Score =  111 bits (267), Expect = 9e-24
 Identities = 63/143 (44%), Positives = 85/143 (59%), Gaps = 3/143 (2%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HICY VT       S VFTGDTLF+ GCGRFFEG   QM  A+   LSSLPDHT V+CGH
Sbjct: 119 HICYHVTDTTTAQ-SGVFTGDTLFISGCGRFFEGHPQQMLSAMDR-LSSLPDHTLVYCGH 176

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
           EYT  N+ F+A + P +E+   K+    D +     T   TI +E+ +NPFMR  +  V+
Sbjct: 177 EYTKSNVAFSAAILPPSEHPITKL--INDLKTTHSTTGMYTIADERNHNPFMRCRDQLVK 234

Query: 156 N---HTGKNDPIDTMKAIRLEKD 97
           +   H   +D  D ++ +RL ++
Sbjct: 235 DKLAHLVGHDVHDEVEVMRLLRE 257


>UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=4; Proteobacteria|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Verminephrobacter eiseniae (strain EF01-2)
          Length = 258

 Score =  111 bits (266), Expect = 1e-23
 Identities = 64/151 (42%), Positives = 87/151 (57%), Gaps = 7/151 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y+   P+     ++F GDTLF GGCGR FEGT  QM  +L   L++LP +T V C 
Sbjct: 111 GHIAYY--CPQMDGAPLLFCGDTLFSGGCGRLFEGTPAQMLASLDR-LAALPGNTLVCCA 167

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL NLKFA  VEP N  ++         R Q +PT+PS +  E+  NPF+RV + AV
Sbjct: 168 HEYTLSNLKFATAVEPDNAALRDYSRHCAALRAQNRPTLPSRMELEREINPFLRVRQAAV 227

Query: 159 ----QNHTGK---NDPIDTMKAIRLEKDTFK 88
               Q H  +   +D +  + A+R  K+ F+
Sbjct: 228 IRAAQGHDAQVQADDAVTVLAALRQWKNGFR 258


>UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=5; Sphingomonadaceae|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 246

 Score =  110 bits (265), Expect = 2e-23
 Identities = 54/119 (45%), Positives = 76/119 (63%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y        +D+ +F GDT+F  GCGR FEGTA+QM+ A +  L +L D T+V+C 
Sbjct: 122 GHIAYHFA-----DDAAIFVGDTMFAMGCGRLFEGTAEQMF-ANMQKLRALDDATRVYCA 175

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
           HEYTL N +FA  V+P NE + A+++  +  R  G+ TVP++IG E+  NPF R  + A
Sbjct: 176 HEYTLSNARFAITVDPANEALAARLAAVEAARAAGEATVPTSIGAERATNPFFRAPDAA 234


>UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas mendocina ymp
          Length = 257

 Score =  110 bits (264), Expect = 2e-23
 Identities = 61/149 (40%), Positives = 88/149 (59%), Gaps = 6/149 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y+         +++  GDTLF GGCGR FEGT  QM+++L + L++LP  T+V+C 
Sbjct: 115 GHIAYY-----HAEQNLLLCGDTLFAGGCGRLFEGTPQQMHQSL-SRLAALPGATRVYCT 168

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL NL+FA  VEP N +V A+++     R++G+ ++PS+I  E   NPF+R  E  V
Sbjct: 169 HEYTLSNLRFAHAVEPHNPDVSARLAEVSRWRDEGRISLPSSIELELATNPFLRTGEPGV 228

Query: 159 QNHTGKND------PIDTMKAIRLEKDTF 91
                +ND      P     ++R  KD F
Sbjct: 229 IKAAKRNDERSSSEPSAVFASLRAWKDRF 257


>UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep:
           Hydroxyacylglutathione hydrolase - Mariprofundus
           ferrooxydans PV-1
          Length = 262

 Score =  109 bits (262), Expect = 4e-23
 Identities = 60/148 (40%), Positives = 83/148 (56%), Gaps = 5/148 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y +       D  +F GDTLF  GCGR FEGT  QM+++L  I + L  +T+++C 
Sbjct: 123 GHIAYLL-------DDALFCGDTLFGAGCGRLFEGTPAQMWQSLQKI-AQLDGNTRIYCA 174

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA- 163
           HEYTL NL FA  V+P N  +K +++   ++R Q  PT+PSTI  EK  NPF+R  + A 
Sbjct: 175 HEYTLANLAFAVMVDPENSTLKERLARDSEKRQQDIPTIPSTIEIEKATNPFLRPLDAAF 234

Query: 162 ----VQNHTGKNDPIDTMKAIRLEKDTF 91
                     K + +     IR +KD F
Sbjct: 235 LSAYAAGKAVKPEALAVFTHIRQQKDHF 262


>UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; Rhodobacteraceae|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Silicibacter pomeroyi
          Length = 255

 Score =  109 bits (261), Expect = 5e-23
 Identities = 57/128 (44%), Positives = 75/128 (58%), Gaps = 2/128 (1%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           VFT D+L   GCGR FEGT DQM+ +L + L++LPD T V  GHEYT  N +FA  V+P 
Sbjct: 129 VFTADSLMALGCGRLFEGTPDQMWASL-SKLAALPDDTLVCSGHEYTQSNARFALSVDPD 187

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKN--DPIDTMKA 115
           N  +K + +     R +G+PTVPS +  EK  NPF+R  +  +Q+  G    DP      
Sbjct: 188 NAALKTRAAEIDQARAEGRPTVPSLLSLEKSTNPFLRAADPGIQSLLGMQGADPARVFAE 247

Query: 114 IRLEKDTF 91
           IR  KD F
Sbjct: 248 IRARKDHF 255


>UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein;
           n=9; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Methylococcus capsulatus
          Length = 256

 Score =  107 bits (258), Expect = 1e-22
 Identities = 54/133 (40%), Positives = 78/133 (58%), Gaps = 2/133 (1%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAH 301
           +D+ +F GDTLF  GCGR FEG+A+QM+++L   L +LP  TKVFC HEYT  N +FA  
Sbjct: 124 DDAALFCGDTLFALGCGRLFEGSAEQMWRSLER-LRALPAETKVFCAHEYTQANARFAVT 182

Query: 300 VEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKN--DPID 127
           +EP N  ++ ++   +  R +G  TVPS + EE   NPF+R     ++   G      ++
Sbjct: 183 IEPGNAALRERVERVEALRREGAATVPSILSEELATNPFLRPESPEIRARLGLPGVPEVE 242

Query: 126 TMKAIRLEKDTFK 88
               IR  KD F+
Sbjct: 243 VFAEIRRRKDVFR 255


>UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=7; Bacteria|Rep: Metallo-beta-lactamase
           superfamily protein - marine gamma proteobacterium
           HTCC2143
          Length = 260

 Score =  107 bits (257), Expect = 2e-22
 Identities = 57/133 (42%), Positives = 74/133 (55%), Gaps = 6/133 (4%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           V+F GDTLF GGCGR FEG    M  +L   L++LP  T+++C HEYTL NL FA  VEP
Sbjct: 129 VLFCGDTLFAGGCGRIFEGNPTMMLNSLQK-LAALPPTTEIYCAHEYTLGNLAFANAVEP 187

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE------LAVQNHTGKNDPI 130
            N  +  +I   + RR    PTVPS +  E   NPF+R TE      +  Q  +  +  +
Sbjct: 188 NNTALNTRIRADKQRREDDIPTVPSLLATELATNPFLRCTEDTVIDSVKAQGGSNGDSEV 247

Query: 129 DTMKAIRLEKDTF 91
           D   A+R  KD F
Sbjct: 248 DIFTAVRRWKDNF 260


>UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5;
           Bacteria|Rep: Hydroxyacylglutathione hydrolase -
           Dinoroseobacter shibae DFL 12
          Length = 256

 Score =  107 bits (256), Expect = 2e-22
 Identities = 56/129 (43%), Positives = 75/129 (58%), Gaps = 2/129 (1%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHV 298
           + VVFTGDTLF+ GCGR FEG    M+ +L   L++LP  T ++C HEYT  N  FA  V
Sbjct: 127 EGVVFTGDTLFVMGCGRLFEGDGPMMHASLQK-LAALPADTVIYCSHEYTEANADFALTV 185

Query: 297 EPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDPID--T 124
           +P N ++K K +  +  R Q KPTVP+T+ EE   NPF+R  +  ++ H G     D   
Sbjct: 186 DPENPDLKDKAARVKALRAQDKPTVPTTLAEELATNPFLRAHDTRIRAHLGLETASDAEV 245

Query: 123 MKAIRLEKD 97
              IR  KD
Sbjct: 246 FTEIRRRKD 254


>UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 268

 Score =  106 bits (255), Expect = 3e-22
 Identities = 56/121 (46%), Positives = 70/121 (57%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI YF  A +      VF GDTLF  GCGR FEGT  QM  +L   L++LP  T V C 
Sbjct: 120 GHIAYFQAAGQGNAAPHVFCGDTLFSCGCGRLFEGTPAQMLASL-DALAALPGDTHVHCA 178

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL N++FA   EP N  +      +Q  R +G PT+P+TI  E+  NPFMR    A+
Sbjct: 179 HEYTLSNIRFALACEPGNTALATWRDDAQALRARGVPTLPTTIAHERAVNPFMRADSDAI 238

Query: 159 Q 157
           +
Sbjct: 239 R 239


>UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Marinomonas|Rep: Hydroxyacylglutathione hydrolase -
           Marinomonas sp. MWYL1
          Length = 257

 Score =  106 bits (254), Expect = 4e-22
 Identities = 59/149 (39%), Positives = 83/149 (55%), Gaps = 7/149 (4%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           H+CYF     E    ++ +GDTLF GGCGR  EGT +QM  A+I I S LP+ T ++  H
Sbjct: 113 HLCYF----SEQETPILLSGDTLFKGGCGRIMEGTHEQMLAAMIKI-SGLPNDTLIYGTH 167

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR--VTELA 163
           EYTL N +FA  +EP N+++       Q  R + KPT+P+ +  EK  NPF+R  +  L 
Sbjct: 168 EYTLANYRFALSLEPNNKDLIESNITCQKLRTEEKPTLPTKLSIEKKTNPFLRSHIEALK 227

Query: 162 VQ-----NHTGKNDPIDTMKAIRLEKDTF 91
           +Q     N     +PI     +R  KD+F
Sbjct: 228 IQAAQQLNEIPAENPIGAFSQVRRAKDSF 256


>UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; cellular organisms|Rep:
           Hydroxyacylglutathione hydrolase, putative - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 249

 Score =  103 bits (248), Expect = 2e-21
 Identities = 58/144 (40%), Positives = 81/144 (56%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y+     +  D++ F GDTLF  GCGR FEGTA+QM+ +L  ++ +LPD T V+C 
Sbjct: 116 GHVSYY-----DAEDAIAFVGDTLFALGCGRLFEGTAEQMWDSLGRLI-ALPDETTVYCA 169

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  N +FA  V+ ++  + A+       R + + TVP+TIG EK  NPF+R   L  
Sbjct: 170 HEYTASNARFALSVD-SSAALAARAEAVFAARARDEATVPTTIGVEKATNPFLRAPLL-- 226

Query: 159 QNHTGKNDPIDTMKAIRLEKDTFK 88
                   P      IR  KD+FK
Sbjct: 227 --RPDAPSPAQAFAEIRAAKDSFK 248


>UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Acinetobacter sp. ADP1|Rep: Putative
           hydroxyacylglutathione hydrolase - Acinetobacter sp.
           (strain ADP1)
          Length = 244

 Score =  103 bits (248), Expect = 2e-21
 Identities = 55/114 (48%), Positives = 74/114 (64%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ YF+   E G+   +F GDTLF  GCGR FEG+ +QMY +L   L++LP  TKV+C 
Sbjct: 120 GHVVYFIE--ETGS---LFCGDTLFAMGCGRVFEGSFEQMYHSL-NRLAALPTTTKVYCT 173

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEYTL N +FA  VEP N  +K ++   Q  R++ + T+PSTI  E   NPF+R
Sbjct: 174 HEYTLANAEFAVTVEPDNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLR 227


>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
           Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
           japonicum
          Length = 255

 Score =  101 bits (242), Expect = 1e-20
 Identities = 48/106 (45%), Positives = 68/106 (64%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHV 298
           +  VF  DTLF  GCGR FEGT   M+ +L+  L +LPD  K++CGHEYT  N+KFA  V
Sbjct: 126 EKTVFAADTLFSIGCGRVFEGTYPMMWDSLLK-LRALPDDFKLYCGHEYTASNVKFALTV 184

Query: 297 EPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           +P N  ++A+ +     R + KPT+PS +G+EK  N F+R  + +V
Sbjct: 185 DPDNAALQARAAEVAKLRAENKPTIPSLLGDEKRANVFLRADDPSV 230


>UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein;
           n=1; Limnobacter sp. MED105|Rep: Metallo-beta-lactamase
           family protein - Limnobacter sp. MED105
          Length = 257

 Score =  101 bits (242), Expect = 1e-20
 Identities = 58/144 (40%), Positives = 87/144 (60%), Gaps = 2/144 (1%)
 Frame = -3

Query: 516 HICYFVTAPEEGN--DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           H+ Y +   +  N  ++ +F GDTLF GGCGR FEG+A QM+++L   L+  P +T+V+C
Sbjct: 127 HLAYVIELKDTMNSEETWMFPGDTLFSGGCGRLFEGSAQQMFESLQK-LNQFPANTRVYC 185

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
            HEYT  N++FA    P ++N++A+ +  +  R QG  T+P+T+G E+L N F+      
Sbjct: 186 AHEYTESNMRFARTYSPESKNIEARENEVRRIREQGLSTIPTTLGIERLSNLFI------ 239

Query: 162 VQNHTGKNDPIDTMKAIRLEKDTF 91
                 KN PI+  K IR  KDTF
Sbjct: 240 ----NAKN-PIE-FKQIRDAKDTF 257


>UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=40; Gammaproteobacteria|Rep: Probable
           hydroxyacylglutathione hydrolase - Escherichia coli
           O157:H7
          Length = 251

 Score =  101 bits (242), Expect = 1e-20
 Identities = 57/147 (38%), Positives = 81/147 (55%), Gaps = 4/147 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHICYF       +   +F GDTLF GGCGR FEGTA QMY++L   LS+LPD T V C 
Sbjct: 113 GHICYF-------SKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKK-LSALPDDTLVCCA 164

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTEL-- 166
           HEYTL N+KFA  + P + ++       ++ R + + T+P  +  E+  N F+R  ++  
Sbjct: 165 HEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDL 224

Query: 165 --AVQNHTGKNDPIDTMKAIRLEKDTF 91
              +   T    P +    +R +KD F
Sbjct: 225 INVINEETLLQQPEERFAWLRSKKDRF 251


>UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas
           aromatica RCB|Rep: Beta-lactamase-like - Dechloromonas
           aromatica (strain RCB)
          Length = 265

 Score =  101 bits (241), Expect = 1e-20
 Identities = 54/120 (45%), Positives = 73/120 (60%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y+  AP       +  GDTLF  GCGR FEGT  QM  +L +I ++LP  T ++C 
Sbjct: 112 GHLAYY--AP-----GALLCGDTLFGAGCGRLFEGTPAQMSASLDSI-AALPGDTLIYCA 163

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  NL+FA  VEP N+ ++A+++     R  G P+VP  + EEK  NPF+R  E AV
Sbjct: 164 HEYTEMNLRFALAVEPNNQALQARVAKVAALRAAGLPSVPLILAEEKATNPFLRCHEAAV 223


>UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Saccharophagus degradans 2-40|Rep:
           Hydroxyacylglutathione hydrolase - Saccharophagus
           degradans (strain 2-40 / ATCC 43961 / DSM 17024)
          Length = 272

 Score =  101 bits (241), Expect = 1e-20
 Identities = 57/132 (43%), Positives = 77/132 (58%), Gaps = 6/132 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GDTLF  GCGR  +GT +Q+  +L  I S+LP  T+V+C HEYTL N+KFA  VEP 
Sbjct: 142 LFCGDTLFSCGCGRILQGTHEQLRTSLDAI-SALPSQTEVYCTHEYTLTNIKFARTVEPQ 200

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTEL----AVQNHTGKN--DPID 127
           ++ +       +  R    P++P+TI  EK  NPF+R  EL    AV+NH         D
Sbjct: 201 SQALIDYEQRVRSLRKNDLPSIPTTIEREKALNPFLRYKELSIQQAVENHLRLKGLTAAD 260

Query: 126 TMKAIRLEKDTF 91
             K +RL KD+F
Sbjct: 261 VFKHLRLWKDSF 272


>UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 321

 Score =  101 bits (241), Expect = 1e-20
 Identities = 53/128 (41%), Positives = 73/128 (57%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHV 298
           D  +FTGDTLF+GGCGRFFEG A QM   +  I S    + K+FCGHEYT  NL++++ V
Sbjct: 184 DECLFTGDTLFIGGCGRFFEGNAAQMLSNMDKISSIQNKNIKIFCGHEYTKSNLEWSSQV 243

Query: 297 EPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDPIDTMK 118
           E  NE +K          + G  T+PST+ +E   N FMR     +Q    + DP   M+
Sbjct: 244 EQNNEVLKQWYQEVLQMTSSGIQTIPSTLQKELQTNVFMRCRTQNLQ-EIFQRDPTQIME 302

Query: 117 AIRLEKDT 94
            +R  K++
Sbjct: 303 TLRAMKNS 310


>UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=7; Prochlorococcus marinus|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Prochlorococcus marinus
          Length = 253

 Score =  100 bits (239), Expect = 2e-20
 Identities = 47/116 (40%), Positives = 76/116 (65%), Gaps = 1/116 (0%)
 Frame = -3

Query: 516 HICYFVTAPEEGN-DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           HIC+F+   +E   D V+F GDTLF  GCGR FEGT +QM+ +L  I ++LP +TK++C 
Sbjct: 122 HICFFLQGSKESKIDPVLFCGDTLFGAGCGRLFEGTPEQMFNSLSRI-NNLPKNTKIYCA 180

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVT 172
           HEYT  NL++A  + P +  ++ ++     R+++G  ++PS + EE+  N F+R +
Sbjct: 181 HEYTEANLRWAKSIFPEDIYIEERLKEVILRKSKGFLSIPSKLSEERKTNLFIRAS 236


>UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione
           hydrolase-like isoform 2; n=1; Pan troglodytes|Rep:
           PREDICTED: hydroxyacylglutathione hydrolase-like isoform
           2 - Pan troglodytes
          Length = 285

 Score =   99 bits (238), Expect = 3e-20
 Identities = 44/91 (48%), Positives = 64/91 (70%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ YF+   +  +   +F+GD L + GCG   EG+A QMY++L   + +LP  TKVFCG
Sbjct: 108 GHMSYFLWEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAE-MGTLPPETKVFCG 166

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDR 247
           HE+TL NL+FA  VEP N++V+AK+SW++ R
Sbjct: 167 HEHTLSNLEFAQKVEPCNDHVRAKLSWAKAR 197


>UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 659

 Score =   99 bits (238), Expect = 3e-20
 Identities = 59/128 (46%), Positives = 76/128 (59%), Gaps = 14/128 (10%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGG--------------CGRFFEGTADQMYKALITIL 376
           ICYF+   ++G    VFTGDTLF+GG              CGRFFEGTA +M+KAL   L
Sbjct: 501 ICYFM---QDGEQKAVFTGDTLFIGGMTEWINAESSAAAGCGRFFEGTAPEMHKALNETL 557

Query: 375 SSLPDHTKVFCGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKL 196
           +SLP+ TKV+ GHEYT  N+KF   V  +    K +     +++ QG      TIG+EKL
Sbjct: 558 ASLPEDTKVYPGHEYTKGNVKFCLAVSQSEPVKKLQAFAEANQQTQGM----FTIGDEKL 613

Query: 195 YNPFMRVT 172
           +N FMRVT
Sbjct: 614 HNVFMRVT 621


>UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=9; Rhodobacteraceae|Rep: Probable
           hydroxyacylglutathione hydrolase - Rhodobacter
           capsulatus (Rhodopseudomonas capsulata)
          Length = 256

 Score =   99 bits (238), Expect = 3e-20
 Identities = 57/146 (39%), Positives = 83/146 (56%), Gaps = 3/146 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI +++  P  G   ++F+GD+L   GCGR FEGT  QM+  L T L++LP  T+V  G
Sbjct: 117 GHIAWYL--PGAG---LLFSGDSLMSWGCGRLFEGTPAQMFDTL-TRLAALPPETRVCSG 170

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  N +FA  +EP N  +  ++      R  G+P++P T+GEE+  NPF+R  + A+
Sbjct: 171 HEYTAANGRFALSLEPGNGRLHDRMDRVTALRLAGEPSLPVTLGEERATNPFLRADDAAL 230

Query: 159 Q---NHTGKNDPIDTMKAIRLEKDTF 91
           +      G   P+    A R  KD F
Sbjct: 231 RAALGLPGDAAPLAVFTAARARKDRF 256


>UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=2; Prochlorococcus marinus|Rep: Putative
           hydroxyacylglutathione hydrolase - Prochlorococcus
           marinus (strain AS9601)
          Length = 303

 Score = 98.7 bits (235), Expect = 7e-20
 Identities = 48/117 (41%), Positives = 73/117 (62%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HI +F+     G + V+F GDTLF GGCGR FEGT  QMY +L  I  SLP +T ++C H
Sbjct: 178 HIAFFLN----GENPVLFIGDTLFSGGCGRIFEGTYQQMYSSLERI-KSLPKNTLIYCAH 232

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTEL 166
           EYT  N+ +A +++P ++++K K+S  + + +  + T+P  + EE   N F+R   L
Sbjct: 233 EYTKANILWALNLKPKDQDIKNKLSEVEKKLSLNELTIPFLLDEEMKINLFLRAKNL 289


>UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           hydroxyacylglutathione hydrolase - Plesiocystis pacifica
           SIR-1
          Length = 270

 Score = 98.3 bits (234), Expect = 9e-20
 Identities = 50/99 (50%), Positives = 64/99 (64%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           ++F GDTLF GGCG  F+G A  M+ +L   L+ LP+ TKV C HEYT  NL+FA  VEP
Sbjct: 126 LLFCGDTLFAGGCGYLFDGPAATMHASLQR-LAGLPESTKVVCAHEYTQDNLRFAWSVEP 184

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRV 175
            N  +  +I      R +G+ TVPSTIG E+  NPF+RV
Sbjct: 185 DNAALAERIREVWAIRARGESTVPSTIGLERATNPFLRV 223


>UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=19; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Brucella suis
          Length = 257

 Score = 97.9 bits (233), Expect = 1e-19
 Identities = 53/129 (41%), Positives = 71/129 (55%), Gaps = 2/129 (1%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           VVFTGDTLF  GCGR FEGT   M+ +L  +++ LP  T ++CGHEYT  N +FA  ++P
Sbjct: 130 VVFTGDTLFALGCGRLFEGTPATMFHSLEKLVA-LPGDTALYCGHEYTQNNARFALTIDP 188

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDPID--TMK 118
            N  +K +       R   + T+PSTI  E   NPF+R  +  ++   G  D  D     
Sbjct: 189 DNSALKERAKEIARLRAHERMTLPSTIALEMATNPFLRWHDRTIRARLGLQDAPDEAVFA 248

Query: 117 AIRLEKDTF 91
            IR  KD F
Sbjct: 249 EIRKRKDMF 257


>UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1,
           mitochondrial precursor; n=12; core eudicotyledons|Rep:
           Hydroxyacylglutathione hydrolase 1, mitochondrial
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 331

 Score = 97.9 bits (233), Expect = 1e-19
 Identities = 50/137 (36%), Positives = 77/137 (56%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI ++         + +FTGD ++   CG   EGT +QM  +L  I+S LPD T ++CG
Sbjct: 192 GHISFYFPG-----SATIFTGDLIYSLSCGTLSEGTPEQMLSSLQKIVS-LPDDTNIYCG 245

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
            E T  NLKFA  VEP NE +++  +     R+QG P++P+T+  EK  NPF+R++   +
Sbjct: 246 RENTAGNLKFALSVEPKNETLQSYATRVAHLRSQGLPSIPTTVKVEKACNPFLRISSKDI 305

Query: 159 QNHTGKNDPIDTMKAIR 109
           +      D     +A+R
Sbjct: 306 RKSLSIPDSATEAEALR 322


>UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione
           hydrolase GloB; n=1; Methylophilales bacterium
           HTCC2181|Rep: putative hydroxyacylglutathione hydrolase
           GloB - Methylophilales bacterium HTCC2181
          Length = 223

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 56/130 (43%), Positives = 76/130 (58%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAH 301
           ND V+F GDTLF  GCGR FEGTA+QM+  L     SL  HT+V+C HEYTL+N++FA  
Sbjct: 111 NDEVLFCGDTLFACGCGRLFEGTAEQMFNTL-QKFKSLKPHTRVYCAHEYTLENIRFAMT 169

Query: 300 VEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDPIDTM 121
           ++  N ++  +  + +DR      T+PSTI +E   NPF     L  +N        +  
Sbjct: 170 LDKDNNHLNKR--FDEDRLKSN--TLPSTIEKEMATNPF-----LLAENS-------EQF 213

Query: 120 KAIRLEKDTF 91
           K IRL+KD F
Sbjct: 214 KVIRLKKDAF 223


>UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Gluconobacter oxydans|Rep: Hydroxyacylglutathione
           hydrolase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 259

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 58/143 (40%), Positives = 77/143 (53%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y V  PE      +F GD LF  GCGR  EGTA +++ +L     SLPD T V  G
Sbjct: 135 GHVSYVV--PEV---PALFCGDVLFSLGCGRLLEGTAQELFDSLHRY-DSLPDQTLVCAG 188

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  NL FA HV+P N  +KA+    +     G+PT+P ++G E+  NPF+   ++A 
Sbjct: 189 HEYTRSNLAFALHVDPDNAALKARAGEIEQLLEAGRPTLPVSLGVERRTNPFLLAPDVA- 247

Query: 159 QNHTGKNDPIDTMKAIRLEKDTF 91
                      T   +R EKDTF
Sbjct: 248 -----------TFARLRREKDTF 259


>UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Methylobacterium extorquens PA1|Rep:
           Hydroxyacylglutathione hydrolase - Methylobacterium
           extorquens PA1
          Length = 158

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 51/130 (39%), Positives = 76/130 (58%), Gaps = 3/130 (2%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           VVF+GDTLF  GCGR  E   + ++++L   L  LPD T V+ GH+Y L N +FA   +P
Sbjct: 30  VVFSGDTLFTLGCGRVMEAEPETLWRSLSRFLD-LPDATAVYSGHDYVLSNGRFALAADP 88

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTG---KNDPIDTM 121
            N ++K +++ ++    QG   +PSTIG+EK  NPF+RV +  +    G    +DP    
Sbjct: 89  DNADLKERVAEAERFAAQGGFLIPSTIGQEKATNPFLRVGQPVLARSAGLEPGSDPAAVF 148

Query: 120 KAIRLEKDTF 91
            A+R  K+ F
Sbjct: 149 TALRAWKNRF 158


>UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including
           glyoxylases; n=1; Hahella chejuensis KCTC 2396|Rep:
           Zn-dependent Hydrolase, including glyoxylases - Hahella
           chejuensis (strain KCTC 2396)
          Length = 257

 Score = 96.7 bits (230), Expect = 3e-19
 Identities = 55/132 (41%), Positives = 71/132 (53%), Gaps = 6/132 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GDTLF  GCGR FEG    M ++L   L  LP  T ++C HEYTL NL+FA  V P 
Sbjct: 127 LFCGDTLFSAGCGRLFEGDPAMMRQSLDK-LKRLPGDTYIYCAHEYTLSNLRFAQAVMPE 185

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR----VTELAVQNHTGK--NDPID 127
           ++ V  +    +  R +G PT+P+ +GEE  YNPF+     V     Q  +G       D
Sbjct: 186 SDEVNKRKLQCESLRARGVPTLPAVLGEEIAYNPFLMAEHPVVRRMAQEVSGSPCATATD 245

Query: 126 TMKAIRLEKDTF 91
           T  AIR  KD F
Sbjct: 246 TFAAIRAWKDRF 257


>UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including
           glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent
           hydrolase, including glyoxylase - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 270

 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 55/146 (37%), Positives = 77/146 (52%), Gaps = 3/146 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y++      +  V+F GDTLF  GCGR FEGTA++M+ +L   L  LP  T  +  
Sbjct: 131 GHVAYWLA-----DSHVLFCGDTLFSLGCGRLFEGTAEEMWASLKK-LRDLPPDTLAYPA 184

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  N +FA  VE  N  +KA++   +  R   +PTVP  + +E+  NPF+R    A+
Sbjct: 185 HEYTAGNGRFARLVERDNGALKARLDEVERLRAHNRPTVPVRLADERAANPFLRADTAAI 244

Query: 159 QNHTG---KNDPIDTMKAIRLEKDTF 91
               G     DP      +R  KD F
Sbjct: 245 ARAVGLEPGTDPALVFAELRRRKDVF 270


>UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9;
           Rhodobacterales|Rep: Hydroxyacylglutathione hydrolase -
           Silicibacter sp. (strain TM1040)
          Length = 271

 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 2/145 (1%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI ++   PE      +F+ D+L + GCGR FEGT   M++ + T LS+LPD T ++ G
Sbjct: 133 GHIAFYY--PEA---PALFSADSLMVMGCGRLFEGTPAMMWQTMTT-LSALPDETLIYSG 186

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  N  FA  +EP N  ++ ++      R  G+PTVP+ +  EK  NPF+R  +  +
Sbjct: 187 HEYTESNAGFALSLEPENAALQKRMDEITKTRQNGQPTVPALLSLEKQTNPFLRAGDPNL 246

Query: 159 QNHTGKN--DPIDTMKAIRLEKDTF 91
           +   G    +  +    IR+ KD F
Sbjct: 247 KKTLGLEGVEDAEVFAHIRVAKDKF 271


>UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=8; Cyanobacteria|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Synechococcus sp. (strain CC9311)
          Length = 260

 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
 Frame = -3

Query: 516 HICYFVTAPEEGND--SVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           HI Y++   E      SV+F GDTLF GGCGR FEGT   M++AL   L SLP  T V C
Sbjct: 128 HIAYWLPQGEISTSLTSVLFCGDTLFSGGCGRLFEGTPADMHRALQR-LGSLPPETLVCC 186

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVT 172
            HEYT  NL++AA  EP +  +  ++   +  R  G  T+PS+I EE   N F+R T
Sbjct: 187 AHEYTEANLRWAAQQEPDDALITNRLRVVEATRRSGSLTLPSSIAEEWRSNLFLRAT 243


>UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrolase
           GloB; n=1; Idiomarina baltica OS145|Rep: Probable
           hydroxyacylglutathione hydrolase GloB - Idiomarina
           baltica OS145
          Length = 252

 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 48/107 (44%), Positives = 67/107 (62%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHV 298
           D+ +F GDTLF GGCGR FEGT + ++ + +  L  LP  T+VFC HEYT  NL FA+ V
Sbjct: 119 DTALFCGDTLFSGGCGRMFEGTPE-LFVSSLDKLRRLPGETRVFCAHEYTQANLTFASLV 177

Query: 297 EPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
           EP N  +K+ +   +  R   + T+PST+  E   NPF+R  + AV+
Sbjct: 178 EPDNAVLKSYLEKIKLMRQNDQITLPSTLQLELAINPFLRFDQSAVR 224


>UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1;
            Chaetomium globosum|Rep: Putative uncharacterized protein
            - Chaetomium globosum (Soil fungus)
          Length = 722

 Score = 95.9 bits (228), Expect = 5e-19
 Identities = 69/160 (43%), Positives = 88/160 (55%), Gaps = 18/160 (11%)
 Frame = -3

Query: 513  ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHE 334
            IC+F+   ++GND VVFTGDTLF GG   FFEG  ++M+KAL   L SLPD T+VF    
Sbjct: 575  ICFFM---QDGNDKVVFTGDTLFHGGEFLFFEGNGEEMHKALNVTLGSLPDDTRVF---- 627

Query: 333  YTLQNLKFAAHVEPTNENVKAKISWSQD-RRNQGKPTVPSTIGEEKLYNPFMRV------ 175
            YT  N KF   V P+   VKA  S++QD +  QGK     TIG+EK +N FMR       
Sbjct: 628  YTGANAKFGVSVLPSGP-VKALQSFAQDNKETQGK----FTIGDEKKHNVFMRPQVRNPG 682

Query: 174  -----------TELAVQNHTGKNDPIDTMKAIRLEKDTFK 88
                        +  +Q  TG+ DPI  M  +R  K+ FK
Sbjct: 683  GHWWLWRLTRRQDPEIQKATGETDPIAIMTKLREMKNNFK 722


>UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9;
           Xanthomonadaceae|Rep: Hydroxyacylglutathione hydrolase -
           Xylella fastidiosa
          Length = 258

 Score = 94.7 bits (225), Expect = 1e-18
 Identities = 52/125 (41%), Positives = 72/125 (57%), Gaps = 3/125 (2%)
 Frame = -3

Query: 483 GNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAA 304
           GND ++F GDTLF  GCG+ FEGT  QM  +L   L++LP  T+V CGHEYTL N  FA 
Sbjct: 118 GND-LLFCGDTLFSLGCGQIFEGTPTQMLASLQR-LAALPIQTRVCCGHEYTLSNAAFAL 175

Query: 303 HVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTG---KNDP 133
           HV+PTN  ++ +   +   R    PT+P ++  E   NPF+R     +   T    +  P
Sbjct: 176 HVDPTNTALQKRRQQANAMRLANLPTLPISLESELNTNPFLRTAAPTIHAATATHLQRTP 235

Query: 132 IDTMK 118
           ID ++
Sbjct: 236 IDEVE 240


>UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Acetobacteraceae|Rep: Hydroxyacylglutathione hydrolase -
           Acidiphilium cryptum (strain JF-5)
          Length = 243

 Score = 92.7 bits (220), Expect = 5e-18
 Identities = 47/114 (41%), Positives = 65/114 (57%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y         D+    GDTLF  GCGR FEGT  Q + +L   L++L   T + CG
Sbjct: 120 GHVTYLF------GDAAAACGDTLFSLGCGRMFEGTPAQFHASL-QALAALDPETLMLCG 172

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           HEYTL N +FA HV+P N  + A+ + ++  R  G PT+P  + +E   NPF+R
Sbjct: 173 HEYTLSNARFARHVDPDNAALAARAAEAERLRAAGAPTLPVRLADELAANPFLR 226


>UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein;
           n=4; Alphaproteobacteria|Rep: Metallo-beta-lactamase
           family protein - Oceanicaulis alexandrii HTCC2633
          Length = 255

 Score = 92.7 bits (220), Expect = 5e-18
 Identities = 53/145 (36%), Positives = 74/145 (51%), Gaps = 2/145 (1%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y+    EE    V F GD+LF  GCGR FEGT  QM   L   L  LP  T ++C 
Sbjct: 117 GHVAYWF---EEAG--VAFVGDSLFALGCGRMFEGTPQQMQAGLAR-LRGLPPETVIYCA 170

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYT  N +FA  V+P N  +++      + R + KPT+P+ +  E   NPF+R  +  +
Sbjct: 171 HEYTQANARFALSVDPENAALQSYARRVDELRAEDKPTIPTVLAAECESNPFLRWDDEGL 230

Query: 159 QNHTGKNDPID--TMKAIRLEKDTF 91
           +   G     D      +R  KD+F
Sbjct: 231 RARLGLQAASDAEVFAELRRRKDSF 255


>UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase
           - Moritella sp. PE36
          Length = 258

 Score = 91.9 bits (218), Expect = 8e-18
 Identities = 45/107 (42%), Positives = 65/107 (60%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAH 301
           N +++F+GDTLF GGCGR  +G+A +++ +L  I  +L ++  V+  HEYT  NL F   
Sbjct: 124 NQTMLFSGDTLFSGGCGRLLDGSAAELFSSLQRI-KALDENILVYPAHEYTQANLMFCYA 182

Query: 300 VEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           VEP N  +K  I  +   R QG PTVP+++  EK  N F+R  E  V
Sbjct: 183 VEPQNSALKKHIEHTAKLRQQGLPTVPNSLKNEKEINVFLRTNEATV 229


>UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=2; Buchnera aphidicola|Rep: Probable
           hydroxyacylglutathione hydrolase - Buchnera aphidicola
           subsp. Acyrthosiphon pisum (Acyrthosiphon pisumsymbiotic
           bacterium)
          Length = 251

 Score = 90.2 bits (214), Expect = 2e-17
 Identities = 51/144 (35%), Positives = 78/144 (54%), Gaps = 3/144 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH+ Y+       +   +F GDTLF  GCGR F+    +MY++ I I+SSLPD T + C 
Sbjct: 113 GHVSYY-------SQPYIFCGDTLFSAGCGRVFKNKHLEMYRS-IKIISSLPDSTLLCCS 164

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           HEYTL NL+F+  + P +  +K  +   + +   G+ ++PS I  EK  N F+R  +  V
Sbjct: 165 HEYTLSNLQFSMFILPNDNFIKLYLKKIEIKLKLGQSSLPSYIFFEKKINLFLRTNDNYV 224

Query: 159 QNHTGKND---PIDTMKAIRLEKD 97
           +   G        +  K +RL+KD
Sbjct: 225 KKSIGLKSTCTDFEVFKRLRLKKD 248


>UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 280

 Score = 89.0 bits (211), Expect = 6e-17
 Identities = 40/88 (45%), Positives = 60/88 (68%)
 Frame = -3

Query: 432 GRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPTNENVKAKISWSQ 253
           GR FEG    M  +L  I   +PD T V+ GHEY + NL+FA +++P NE+V  K+++ +
Sbjct: 155 GRMFEGPPSLMLSSLDKICQ-IPDDTLVWPGHEYAVDNLRFAHNIDPANEDVTRKLNYVE 213

Query: 252 DRRNQGKPTVPSTIGEEKLYNPFMRVTE 169
           +RR + + T PST+GEEK YNPF+R ++
Sbjct: 214 ERRKERRITSPSTLGEEKSYNPFLRTSQ 241


>UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to
           myofibrillogenesis regulator 1; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to myofibrillogenesis
           regulator 1 - Monodelphis domestica
          Length = 286

 Score = 75.8 bits (178), Expect(2) = 2e-16
 Identities = 35/67 (52%), Positives = 44/67 (65%)
 Frame = -3

Query: 345 CGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTEL 166
           CGHEY+ +NL FA  VEP N   + K+ W Q +R Q + T PST+GEEK YNPF+R   L
Sbjct: 190 CGHEYSEENLSFAGLVEPENMAREKKMQWVQQQRLQYRSTCPSTLGEEKTYNPFLRTHCL 249

Query: 165 AVQNHTG 145
           A+Q   G
Sbjct: 250 ALQEALG 256



 Score = 32.3 bits (70), Expect(2) = 2e-16
 Identities = 13/30 (43%), Positives = 17/30 (56%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCG 430
           GH+ Y +        S +F+GD LFL GCG
Sbjct: 162 GHMVYVLDGEPYKGPSCLFSGDLLFLSGCG 191


>UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily protein
           precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
           Metallo-beta-lactamase superfamily protein precursor -
           Thiomicrospira crunogena (strain XCL-2)
          Length = 268

 Score = 87.0 bits (206), Expect = 2e-16
 Identities = 50/146 (34%), Positives = 80/146 (54%), Gaps = 6/146 (4%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           HIC++   PE      +F+GDTLF GGCG+ ++   +QM ++L+  L +L D   V+CGH
Sbjct: 117 HICFY--HPE-----ALFSGDTLFTGGCGKIWQNPPEQMAESLLK-LRALNDDCMVYCGH 168

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR-----VT 172
           EYT  NL FA   EP    +  +++  +    +  P VP+ +G EK  NPF+R     + 
Sbjct: 169 EYTYANLNFAKIAEPNTPAILDRLAEVKTNTQRNIPCVPARLGLEKQTNPFLRFDHPPLM 228

Query: 171 ELAVQNHTGKNDPIDTMKA-IRLEKD 97
           +  ++     N+ + T+ A +R  KD
Sbjct: 229 QTLMERQAQPNESVSTLFATLRAWKD 254


>UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Psychrobacter|Rep: Hydroxyacylglutathione hydrolase -
           Psychrobacter sp. PRwf-1
          Length = 259

 Score = 87.0 bits (206), Expect = 2e-16
 Identities = 53/148 (35%), Positives = 78/148 (52%), Gaps = 6/148 (4%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           H+ Y +   +EG+  V F GDTLF  GCGR F GT +Q++ +     + LPD+T  +  H
Sbjct: 116 HLAYVLD--KEGHKQV-FCGDTLFSAGCGRVFTGTIEQLHDSFKRF-NKLPDNTLFYPAH 171

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA-- 163
           EYT  NLKF   +EP N  ++  ++  +     G+ ++P T+  EK  N F+R  EL+  
Sbjct: 172 EYTAANLKFGLSIEPDNAAMQQCLTEVESMTALGQSSLPVTLAHEKQVNVFLRTQELSVI 231

Query: 162 --VQNHTGKND--PIDTMKAIRLEKDTF 91
             VQN     D   +    A+R  KD F
Sbjct: 232 DGVQNQVTLADTKSLTVFAALRALKDEF 259


>UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Thiobacillus denitrificans ATCC 25259|Rep:
           Hydroxyacylglutathione hydrolase - Thiobacillus
           denitrificans (strain ATCC 25259)
          Length = 256

 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 50/130 (38%), Positives = 70/130 (53%), Gaps = 6/130 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GDTLF  GCG+ FEG A  M  A +  L++LP  T+V C HEYTL N+ FA  ++  
Sbjct: 124 LFCGDTLFGCGCGKLFEGDAAMM-SASLDALAALPPTTRVCCAHEYTLSNIDFAKTIDGA 182

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ----NHTGKND--PID 127
           N  +  +    +  R Q +PT+PST+  E+  NPF+R  +  ++       G  D  P  
Sbjct: 183 NPALLERERIDRAARAQNRPTLPSTLALERTTNPFLRFHDADMRAFAVGELGSPDPGPAT 242

Query: 126 TMKAIRLEKD 97
              AIR  KD
Sbjct: 243 VFGAIRAAKD 252


>UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase
           (Glyoxalase II) (GLX II) protein; n=1; alpha
           proteobacterium HTCC2255|Rep: Putative
           hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX
           II) protein - alpha proteobacterium HTCC2255
          Length = 255

 Score = 85.4 bits (202), Expect = 7e-16
 Identities = 52/145 (35%), Positives = 73/145 (50%), Gaps = 2/145 (1%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI YF    ++     VFTGD+L   GCGR FEGT   M+  L  +   LP  T V+ G
Sbjct: 117 GHISYFFKDSKK-----VFTGDSLMSLGCGRLFEGTHKMMWNTL-KLFMKLPKETLVYSG 170

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR--VTEL 166
           HEY+  N KFA  V+ +N  +K      QD     K TVP+++  E   NPF+R  + E 
Sbjct: 171 HEYSYSNAKFALSVDSSNTRLKEYYKEIQDLLKDNKYTVPTSLELEFAINPFLRSALPEF 230

Query: 165 AVQNHTGKNDPIDTMKAIRLEKDTF 91
            +     +    +  + +R+ KD F
Sbjct: 231 KLGLDMCQKTDHEVFQYLRILKDNF 255


>UniRef50_Q71KM2 Cluster: Glyoxalase II; n=8; Plasmodium|Rep:
           Glyoxalase II - Plasmodium falciparum
          Length = 322

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 51/138 (36%), Positives = 75/138 (54%), Gaps = 9/138 (6%)
 Frame = -3

Query: 474 SVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVE 295
           ++ FTGD LF+ G G+ FE   + +Y ++  +      +  +FCGHEYTL NLKFA  V+
Sbjct: 184 NIFFTGDFLFISGIGKNFEQDNEDLYNSINKLKLLDKQNIYIFCGHEYTLDNLKFALTVD 243

Query: 294 PTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTG-----KNDPI 130
            TN+N+ +      +  N+  PTVP+ +  E LYNPF+R  +  V+         KN  I
Sbjct: 244 STNKNLLSFYDHVVN-SNKNYPTVPTLLEHEYLYNPFLRCDQNDVRKSIDLYAKKKNIKI 302

Query: 129 ----DTMKAIRLEKDTFK 88
               D +  +RL KD FK
Sbjct: 303 QQESDYIVILRLMKDNFK 320


>UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF15037, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 227

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 35/64 (54%), Positives = 49/64 (76%), Gaps = 1/64 (1%)
 Frame = -3

Query: 408 DQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPTNENVKAKISWSQDR-RNQGK 232
           D MYKALI IL  LP  T+V+CGHEYT+ NLKFA HVEP N+ +K K++W+++R   + +
Sbjct: 121 DAMYKALIEILGRLPPETRVYCGHEYTISNLKFARHVEPDNDVIKNKLAWAKERHERENQ 180

Query: 231 PTVP 220
           P++P
Sbjct: 181 PSLP 184


>UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Pasteurellaceae|Rep: Hydroxyacylglutathione hydrolase -
           Mannheimia haemolytica PHL213
          Length = 235

 Score = 82.2 bits (194), Expect = 7e-15
 Identities = 50/119 (42%), Positives = 62/119 (52%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y       G D  +F GD LF GGCGR F G     + AL     +LP+  K +  
Sbjct: 112 GHISYLF-----GYD-YLFCGDALFSGGCGRVFTGDYQAQFDALQRF-KNLPNSVKAYPA 164

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
           HEYT  NLKFA  V P +  +          R+Q KPT+P+TIG E   NPFM+  +LA
Sbjct: 165 HEYTKSNLKFAEAVLPPSCVLSEYQEQVDLLRSQNKPTLPTTIGLEMQVNPFMQAVDLA 223


>UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia
           glossinidia endosymbiont of Glossina brevipalpis|Rep:
           GloB protein - Wigglesworthia glossinidia brevipalpis
          Length = 251

 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 43/95 (45%), Positives = 55/95 (57%)
 Frame = -3

Query: 465 FTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPTN 286
           F GDTLF  GCGR FEG+A  MY + I  ++SLP +T +  GHEYTLQNL FA  V P N
Sbjct: 123 FCGDTLFSAGCGRLFEGSAKDMYFS-IKKINSLPPNTLICAGHEYTLQNLNFAISVFPKN 181

Query: 285 ENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFM 181
             +       +      KPT+PS +  E+  N F+
Sbjct: 182 TILSMYKKKVEKLNFYKKPTLPSALYLERQINIFL 216


>UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Vibrio vulnificus YJ016|Rep: Putative
           hydroxyacylglutathione hydrolase - Vibrio vulnificus
           (strain YJ016)
          Length = 247

 Score = 79.4 bits (187), Expect = 5e-14
 Identities = 48/127 (37%), Positives = 73/127 (57%), Gaps = 1/127 (0%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GD LF  GCGR      D MY +L  I  S+ D TK++  HEYTL NLKFA +++P 
Sbjct: 124 LFCGDVLFSAGCGRVGSNYKD-MYLSLKKI-KSMDDKTKIYFSHEYTLDNLKFAHYIDPK 181

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE-LAVQNHTGKNDPIDTMKAI 112
           N+N+   I   +++ +    + P+T+  EK  NPF+R++E + ++N    N+  D    +
Sbjct: 182 NKNIINYIEVFKEKPD--TVSAPTTLLLEKEINPFLRLSENIDIKNKI--NNEFDAFVYL 237

Query: 111 RLEKDTF 91
           R  KD F
Sbjct: 238 RKLKDKF 244


>UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Buchnera aphidicola (Baizongia pistaciae)|Rep:
           Probable hydroxyacylglutathione hydrolase - Buchnera
           aphidicola subsp. Baizongia pistaciae
          Length = 249

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 39/98 (39%), Positives = 62/98 (63%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GD++F GGCGR   G   +MY +L TI S LP+ T ++C HEYT  NL+F   + P 
Sbjct: 123 LFCGDSIFSGGCGRVKNGMMIKMYNSLRTI-SKLPNDTLIYCSHEYTRSNLEFFKKIFPK 181

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRV 175
           N N+     ++  ++++ + T+PST+  EK  NPF+++
Sbjct: 182 NLNILN--YYNNIKKSKTQCTLPSTLKIEKKINPFLQL 217


>UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=8; Trypanosomatidae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Leishmania
           major
          Length = 295

 Score = 75.8 bits (178), Expect = 6e-13
 Identities = 47/132 (35%), Positives = 68/132 (51%), Gaps = 13/132 (9%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSV-VFTGDTLFLGGCGRFFEGTADQMYKALITILS-------SLP 364
           GH+ Y V  P+  ND V +FTGDT+F+ G G FFEG    M +A+  +         +L 
Sbjct: 142 GHVLYKVQHPQHPNDGVALFTGDTMFIAGIGAFFEGDEKDMCRAMEKVYHIHKGNDYALD 201

Query: 363 DHTKVFCGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRR-----NQGKPTVPSTIGEEK 199
             T +F GHEYT   + F+    P   + +     +Q  +       G P+VPS++ EEK
Sbjct: 202 KVTFIFPGHEYTAGFMTFSEKTFPDRASNELAFIQAQRAKYAAAVKTGDPSVPSSLAEEK 261

Query: 198 LYNPFMRVTELA 163
           L N F+RV + A
Sbjct: 262 LQNLFLRVADPA 273


>UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase,
           mitochondrial precursor; n=10; Saccharomycetales|Rep:
           Hydroxyacylglutathione hydrolase, mitochondrial
           precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 285

 Score = 75.8 bits (178), Expect = 6e-13
 Identities = 49/129 (37%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHT-----KV 349
           ICY++   E G +  +FTGDTLF+ GCGRFFEGT   M  AL  I+      T     K+
Sbjct: 136 ICYYIKDLETG-EQCIFTGDTLFIAGCGRFFEGTGRDMDMALNQIMLRAVGETNWNKVKI 194

Query: 348 FCGHEYTLQNLKF-AAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVT 172
           + GHEYT  N+ F  A +       K   +  Q  ++    T   T+ +E  YNPFMR+ 
Sbjct: 195 YPGHEYTKGNVSFIRAKIYSDIGQNKEFDALEQYCKSNECTTGHFTLRDELGYNPFMRLD 254

Query: 171 ELAVQNHTG 145
           + AV+   G
Sbjct: 255 DRAVRLAVG 263


>UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Sodalis glossinidius str. 'morsitans'|Rep: Putative
           hydroxyacylglutathione hydrolase - Sodalis glossinidius
           (strain morsitans)
          Length = 250

 Score = 74.5 bits (175), Expect = 1e-12
 Identities = 43/130 (33%), Positives = 70/130 (53%), Gaps = 4/130 (3%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPT 289
           +F GDT+F  G GR FEGT  QMY++   + + L   T +   HEYTL NL FAA + P 
Sbjct: 122 LFCGDTVFSAGSGRLFEGTPRQMYESFQKV-NQLSSATLICAAHEYTLSNLNFAAALLPQ 180

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQN----HTGKNDPIDTM 121
           +  +       ++ R + +P++P+ +  E+  N F+R  ++ +QN    H   ++     
Sbjct: 181 DSVITDYQRKIKELRLKNQPSMPTKLHLERQINLFLRCHDVNLQNKLNVHPAPSEEWRVF 240

Query: 120 KAIRLEKDTF 91
            A+R +KD F
Sbjct: 241 AALREKKDHF 250


>UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=2; Candidatus Blochmannia|Rep: Probable
           hydroxyacylglutathione hydrolase - Blochmannia
           floridanus
          Length = 256

 Score = 72.9 bits (171), Expect = 4e-12
 Identities = 42/132 (31%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
 Frame = -3

Query: 474 SVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVE 295
           S +F+GDT+F  GCG    G    MYK+L+ I   LP +T ++ GHEYTL NL FA  + 
Sbjct: 122 SWLFSGDTIFSAGCGTIQTGYTQAMYKSLLKI-QCLPKNTLIYSGHEYTLLNLNFAISIL 180

Query: 294 PTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTG----KNDPID 127
           P +  +   +        + K   P+T+  E   NPF+R  ++ +Q          +   
Sbjct: 181 PQDTLIINYLKKITKVLKKNKLLQPTTLQLELKINPFLRCNDINIQKSLNLFPKPGEEWK 240

Query: 126 TMKAIRLEKDTF 91
            ++A+R +KD +
Sbjct: 241 ILQALRNKKDLY 252


>UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           unclassified Gammaproteobacteria (miscellaneous)|Rep:
           Hydroxyacylglutathione hydrolase - marine gamma
           proteobacterium HTCC2143
          Length = 258

 Score = 72.9 bits (171), Expect = 4e-12
 Identities = 39/120 (32%), Positives = 61/120 (50%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           H+C+ V   E+G +  VFTGDTLF  G G    G  D +Y+ +      L D+ +V+ GH
Sbjct: 118 HLCFLVL--EQGIEVAVFTGDTLFNAGVGHCRSGDVDSLYQTIAEQFHCLDDNVRVYPGH 175

Query: 336 EYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
           +Y   NL+F   VEP N   +  +  +        P V + IG+E+ +N F R+    ++
Sbjct: 176 DYLENNLRFTLSVEPDNRQAQEWLPRAIAADLTVAPLV-TRIGDEREFNSFFRLANRQIR 234


>UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep:
           Glyoxylase - Ostreococcus tauri
          Length = 512

 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 37/106 (34%), Positives = 58/106 (54%), Gaps = 1/106 (0%)
 Frame = -3

Query: 492 PEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLK 313
           P   N   +FTGD +  GG G FF G A+  Y+ L   L+  PD   +F GHEY   NL+
Sbjct: 283 PTLANAKAMFTGDAIINGGVGAFFHGNANDCYENLHVRLAPTPDDCLIFSGHEYMETNLR 342

Query: 312 FAAHVEPTNENVKAKISWS-QDRRNQGKPTVPSTIGEEKLYNPFMR 178
           FA  ++  ++ + A   ++ +  R+Q   T+PS++  E+  NP+ R
Sbjct: 343 FAKAID-VDDQITANCFFAIRLHRHQDAGTMPSSLRVERRLNPYFR 387


>UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=17; Pasteurellaceae|Rep: Probable
           hydroxyacylglutathione hydrolase - Haemophilus
           influenzae
          Length = 238

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 42/109 (38%), Positives = 61/109 (55%), Gaps = 5/109 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHV 298
           D+ +F GD LF  GCGR F G    M++ L   L++LPD T V   HEYTL NL FA  V
Sbjct: 118 DNHLFCGDALFSAGCGRVFTGNYALMFEGL-QRLNTLPDETIVCPAHEYTLGNLAFAETV 176

Query: 297 EPTNENV-KAKIS----WSQDRRNQGKPTVPSTIGEEKLYNPFMRVTEL 166
                 V K+ +     + + +R + KP++P+T+  E+  NPF++   L
Sbjct: 177 LVDKSAVEKSAVEKQRIFVETQRAENKPSLPTTLKLEREINPFLQAKTL 225


>UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Anaeromyxobacter|Rep: Hydroxyacylglutathione hydrolase -
           Anaeromyxobacter sp. Fw109-5
          Length = 255

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 36/113 (31%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEG-TADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           + TGDTLF GGCG    G    ++ ++ +  +++L    +V  GH+Y   NL FA  +EP
Sbjct: 122 LLTGDTLFWGGCGNCRHGGDPARLAQSFLGPIAALDGALEVHPGHDYAEANLPFALALEP 181

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDP 133
            N   +A++   +  R  G     ST+ EE+  NPF+RV + ++++      P
Sbjct: 182 GNAAARARLEVVERARAAGAEPPASTLAEEREVNPFLRVAKPSIRDAIAARSP 234


>UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=1; Bdellovibrio bacteriovorus|Rep:
           Hydroxyacylglutathione hydrolase GloB - Bdellovibrio
           bacteriovorus
          Length = 251

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 41/121 (33%), Positives = 61/121 (50%), Gaps = 8/121 (6%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GHI Y+           +F+GD +F  GCGR FEGT +Q Y++L  I   LP  T ++C 
Sbjct: 119 GHIAYW-----NQKHKWLFSGDVIFGLGCGRLFEGTFEQGYESLQRI-KKLPPQTLIYCT 172

Query: 339 HEYTLQNLKFA--------AHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPF 184
           HEYT  NL+F           +   +E ++   +   +RR    P+VP  +  E+  NPF
Sbjct: 173 HEYTKSNLEFCRILTNQDNTPITGDSEALELYANELSNRRELNLPSVPLKLSIEESVNPF 232

Query: 183 M 181
           +
Sbjct: 233 L 233


>UniRef50_Q24F45 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Tetrahymena thermophila SB210|Rep:
           Hydroxyacylglutathione hydrolase, putative - Tetrahymena
           thermophila SB210
          Length = 305

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 34/127 (26%), Positives = 66/127 (51%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           ++FTG+TL +   G        QM + +   L S P+ T +F   +  L++L FA  ++P
Sbjct: 175 IIFTGETLLISSIGDIQPNGHKQMLETIFK-LKSFPNETLLFPSKDGQLEDLLFAKSLDP 233

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDPIDTMKAI 112
            N  +  KI  ++    +    +PS++ EEK  NP++R+ +  +  +    +P D +K +
Sbjct: 234 GNPVINLKIQLAKQAIEKKTHILPSSLLEEKNCNPYLRLHDNQILKNANARNPTDALKNL 293

Query: 111 RLEKDTF 91
           +  ++TF
Sbjct: 294 KSLQNTF 300


>UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           cellular organisms|Rep: Hydroxyacylglutathione hydrolase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 263

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEG-TADQMYKALITILSSLPDHTKVFC 343
           GH    +          +F+GDTLF  G G    G   + +Y      L+ LPD T V+ 
Sbjct: 114 GHTMCHICLRSHTEQPALFSGDTLFNAGAGNVHNGGDVNALYATFAEQLARLPDDTLVYP 173

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
           GH+Y   NL+F    EP N   KA +    D  +  K  V +T+ +EK +N F+R++  +
Sbjct: 174 GHDYIENNLRFTLAREPDNAAAKALLPSVTD-HDPAKSAV-TTLKDEKEFNTFLRLSSPS 231

Query: 162 V 160
           V
Sbjct: 232 V 232


>UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Deltaproteobacteria|Rep: Hydroxyacylglutathione
           hydrolase - Syntrophus aciditrophicus (strain SB)
          Length = 235

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 35/103 (33%), Positives = 52/103 (50%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHV 298
           D+++ TGDTLF G  G  F G     Y ++  IL +LP  T ++ GH+Y   +L  A H+
Sbjct: 112 DTILLTGDTLFNGTVGNCFSGDIHSFYSSIRKIL-TLPPETVIYAGHDYVRDSLAMARHL 170

Query: 297 EPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE 169
           EP N  +   +S            V ST+ +E   NP++R  E
Sbjct: 171 EPDNPAIDDFLSVYDPNH------VYSTLADELRINPYLRFNE 207


>UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 2
           SCAF14661, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 400

 Score = 62.5 bits (145), Expect = 6e-09
 Identities = 31/55 (56%), Positives = 34/55 (61%)
 Frame = -3

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
           GHEY   NL FAA VEP N   + K  W   +R Q   T PSTIGEEK YNPF+R
Sbjct: 307 GHEYAEDNLLFAAEVEPRNSVRENKYQWVLLQRGQKLCTSPSTIGEEKQYNPFLR 361



 Score = 34.3 bits (75), Expect = 1.7
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCG 430
           GH+ Y +     G+ S +F+GD +FL GCG
Sbjct: 168 GHMIYLLDGRTVGSPSSLFSGDLVFLSGCG 197


>UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Reinekea sp. MED297|Rep: Hydroxyacylglutathione
           hydrolase - Reinekea sp. MED297
          Length = 258

 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 33/123 (26%), Positives = 57/123 (46%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCG 340
           GH  +    P+      +   DTLF  G G    G   ++Y+ +  + S L   T++F G
Sbjct: 116 GHGVFLYQDPQLSERDFLVCADTLFNAGVGNTRSGNVSELYQTVDRLKSLLRPQTRLFPG 175

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAV 160
           H+Y   NLKF  +  P  E  +  +  + D++     +V   + +E  YNPF+ +    +
Sbjct: 176 HDYICTNLKFVLNHFPDCEPARTTLD-TVDKQTPDTRSV-MRLADEYRYNPFLSLQADWI 233

Query: 159 QNH 151
           +NH
Sbjct: 234 ENH 236


>UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2;
           Thermoprotei|Rep: Zn-dependent hydrolase - Cenarchaeum
           symbiosum
          Length = 203

 Score = 51.6 bits (118), Expect(2) = 1e-06
 Identities = 23/51 (45%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           D  +FTGDTLF+G CGR     G+A  +Y ++  +L  L D   V+CGH+Y
Sbjct: 121 DGKIFTGDTLFVGSCGRVDLPGGSARDLYGSIFGVLYRLDDSLVVYCGHDY 171



 Score = 23.0 bits (47), Expect(2) = 1e-06
 Identities = 9/14 (64%), Positives = 11/14 (78%)
 Frame = -3

Query: 219 STIGEEKLYNPFMR 178
           ST+G+EK  NP MR
Sbjct: 177 STLGDEKKSNPVMR 190


>UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1;
           Syntrophus aciditrophicus SB|Rep: Hydroxyacylglutathione
           hydrolase W - Syntrophus aciditrophicus (strain SB)
          Length = 257

 Score = 42.7 bits (96), Expect(2) = 4e-06
 Identities = 23/48 (47%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRF-FEGT-ADQMYKALITILSSLPDHTKVFCGHEY 331
           VFTGDTLF+   GR    G+ A QM++++   L +LPD T+V  GH Y
Sbjct: 191 VFTGDTLFVESVGRTDLNGSSASQMFRSIREKLLTLPDDTQVLPGHNY 238



 Score = 29.9 bits (64), Expect(2) = 4e-06
 Identities = 13/22 (59%), Positives = 17/22 (77%)
 Frame = -3

Query: 243 NQGKPTVPSTIGEEKLYNPFMR 178
           N G+ T  STIG EK+YNPF++
Sbjct: 237 NYGR-TSTSTIGHEKIYNPFLQ 257


>UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1;
           Encephalitozoon cuniculi|Rep: HYDROXYACYL GLUTATHION
           HYDROLASE - Encephalitozoon cuniculi
          Length = 263

 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 25/65 (38%), Positives = 34/65 (52%)
 Frame = -3

Query: 462 TGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPTNE 283
           TGDTL   GCG+FF GT  QM K +  I   +     +  GH+Y+ QN++F        E
Sbjct: 156 TGDTLLFLGCGKFFGGTPGQMIKNIEEIKKRVNHDAVLLYGHDYSEQNIRFTEEFYHVPE 215

Query: 282 NVKAK 268
            +K K
Sbjct: 216 EIKKK 220


>UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 209

 Score = 48.0 bits (109), Expect(2) = 7e-06
 Identities = 26/64 (40%), Positives = 41/64 (64%), Gaps = 2/64 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G  CY++   +EG   V+F+GDT+F G  GR  F EG+   +  +L  +L +LPD+T+V+
Sbjct: 136 GSCCYYLK--DEG---VLFSGDTVFCGSVGRTDFPEGSTAAIVNSLHRLLEALPDNTEVY 190

Query: 345 CGHE 334
            GH+
Sbjct: 191 PGHD 194



 Score = 23.8 bits (49), Expect(2) = 7e-06
 Identities = 9/13 (69%), Positives = 11/13 (84%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           +TIG EK YNPF+
Sbjct: 197 TTIGYEKRYNPFV 209


>UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|Rep:
           Bll1007 protein - Bradyrhizobium japonicum
          Length = 345

 Score = 44.4 bits (100), Expect(2) = 1e-05
 Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           VFTGDTL + G GR  F  G++   Y ++   L  LPD T VF  H+Y
Sbjct: 126 VFTGDTLLIRGTGRTDFQNGSSRAQYDSIFNRLLKLPDETMVFPAHDY 173



 Score = 26.6 bits (56), Expect(2) = 1e-05
 Identities = 11/15 (73%), Positives = 13/15 (86%)
 Frame = -3

Query: 219 STIGEEKLYNPFMRV 175
           STIGEEK YNP ++V
Sbjct: 179 STIGEEKRYNPRLQV 193


>UniRef50_Q6MNF6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=3; Proteobacteria|Rep: Metallo-beta-lactamase
           superfamily protein - Bdellovibrio bacteriovorus
          Length = 286

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 35/114 (30%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
 Frame = -3

Query: 477 DSVVFTGDTLFL--GGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQN--L 316
           +  +FTGD LF+   G GR  F  G+A+ +Y ++   + SLP++T++F GH+Y      L
Sbjct: 155 EDAIFTGDALFMPDSGTGRCDFPAGSAENLYDSVTGKIYSLPENTRIFVGHDYQPNGRAL 214

Query: 315 KFAAHV-EPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQ 157
            +   V E  N+N++ K   S++   + +    +T+   KL  P ++V   A Q
Sbjct: 215 MYQTTVNEEKNQNIQLKGHTSKEDFVKFRQERDATLAAPKLLLPSIQVNIRAGQ 268


>UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamily
           protein; n=11; Bacteria|Rep: Possible
           Beta-lactamase-like superfamily protein - Psychrobacter
           arcticum
          Length = 249

 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           VFTGD L + GCGR  F  G AD +YK++   L SLPD T V+  H+Y
Sbjct: 126 VFTGDALLIDGCGRTDFQNGDADALYKSVRQKLFSLPDDTLVYPAHDY 173


>UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
           Metallo-beta-lactamase superfamily protein -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 235

 Score = 46.0 bits (104), Expect(2) = 2e-05
 Identities = 22/54 (40%), Positives = 35/54 (64%), Gaps = 2/54 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQ 322
           D+ + TGDTLF+ GCGR  F  G +  ++++L   L  LP HT++  GH+Y ++
Sbjct: 126 DNNLITGDTLFVYGCGRTDFPSGDSRALFESL-QKLKKLPPHTQILSGHDYGIE 178



 Score = 24.2 bits (50), Expect(2) = 2e-05
 Identities = 9/18 (50%), Positives = 12/18 (66%)
 Frame = -3

Query: 219 STIGEEKLYNPFMRVTEL 166
           ST+ E+  YNPFM +  L
Sbjct: 181 STLSEQITYNPFMTICSL 198


>UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1;
           Acinetobacter baumannii ATCC 17978|Rep:
           Beta-lactamase-like protein - Acinetobacter baumannii
           (strain ATCC 17978 / NCDC KC 755)
          Length = 231

 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 22/50 (44%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
 Frame = -3

Query: 474 SVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +++FTGD L + GCGR  F +G A  +Y ++   L SLPD+T ++ GH+Y
Sbjct: 124 NMIFTGDALLIDGCGRTDFQQGNAGTLYDSIHKQLFSLPDNTILYPGHDY 173


>UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein;
           n=1; Plesiocystis pacifica SIR-1|Rep:
           Metallo-beta-lactamase family protein - Plesiocystis
           pacifica SIR-1
          Length = 234

 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 24/51 (47%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           DS+V TGDTLF+ GCGR  F  G  + M++ L  ++S LP  T ++ GH Y
Sbjct: 134 DSIV-TGDTLFVNGCGRCDFVGGDPELMFETLEALMSKLPKDTVMYPGHHY 183


>UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Hydroxyacylglutathione
           hydrolase - Sphingomonas wittichii RW1
          Length = 256

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 2/142 (1%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDS-VVFTGDTLFLGGCGRFFEGT-ADQMYKALITILSSLPDHTKVFC 343
           H+       + G D   +  GDTLF  G G    G     ++  +  +  +L   T+++ 
Sbjct: 119 HVGLLGEGADRGEDEPFLLCGDTLFGAGVGNVGHGGHGPTLFATVDRLRRTLDPRTRLYP 178

Query: 342 GHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELA 163
           GH+Y  +NL F    EP N   +A +         G     +T+ EE+  N F R+ + A
Sbjct: 179 GHDYLARNLGFTLRHEPDNRAARALL------ETIGPAPRFTTMAEEEEINLFFRLDQPA 232

Query: 162 VQNHTGKNDPIDTMKAIRLEKD 97
           V+   G+ D      AIR  +D
Sbjct: 233 VRAAFGEADREARFLAIRRARD 254


>UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2;
           Synechococcus|Rep: Beta-lactamase-like - Synechococcus
           sp. RS9917
          Length = 370

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
 Frame = -3

Query: 474 SVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAH 301
           S  FTGD L + GCGR  F +G A  +Y+++   + SLPD   ++ GH+Y+ + +   A 
Sbjct: 141 SAAFTGDALLIRGCGRSDFQQGNAHTLYRSITEQILSLPDQCLLYPGHDYSGRQVTSVAE 200

Query: 300 VEPTN 286
               N
Sbjct: 201 ERALN 205


>UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular
           organisms|Rep: ENSANGP00000000940 - Anopheles gambiae
           str. PEST
          Length = 248

 Score = 45.6 bits (103), Expect(2) = 1e-04
 Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 2/62 (3%)
 Frame = -3

Query: 510 CYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           C      E+G   + FTGDTL + GCGR  F EG +  +Y+++   + +LP++ ++F  H
Sbjct: 131 CMTFLVEEQG---IAFTGDTLLIRGCGRTDFQEGDSRSLYRSVHERIFTLPENFRLFPAH 187

Query: 336 EY 331
           +Y
Sbjct: 188 DY 189



 Score = 22.2 bits (45), Expect(2) = 1e-04
 Identities = 8/16 (50%), Positives = 11/16 (68%)
 Frame = -3

Query: 234 KPTVPSTIGEEKLYNP 187
           K  + +T+ EEK YNP
Sbjct: 190 KGNMETTVAEEKRYNP 205


>UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3;
           Leptospira|Rep: Zn-dependent hydrolase - Leptospira
           borgpetersenii serovar Hardjo-bovis (strain JB197)
          Length = 269

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
 Frame = -3

Query: 516 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEG-TADQMYKALITILSSLPDHTKVFCG 340
           H+C  +   E      +FTGDT+F  G G    G   + + K ++     L +   ++ G
Sbjct: 119 HVCLLLV--ENQKPKAIFTGDTIFNAGVGNCHHGGDPEVLAKTILEQFYPLEEEILLYPG 176

Query: 339 HEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTE--L 166
           H+Y   NLKF   ++P+N++    +     R ++    + + + +E+  N F +  +  L
Sbjct: 177 HDYLETNLKFTLSLDPSNQDAIRTLE-ECSRLSKNVEFLTTDLRKERKINTFFQCDKPSL 235

Query: 165 AVQNHTGKNDP 133
            ++ +  K  P
Sbjct: 236 ELRKNVSKKIP 246


>UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein;
           n=14; Bacteria|Rep: Metallo-beta-lactamase domain
           protein - Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 238

 Score = 44.0 bits (99), Expect(2) = 2e-04
 Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           N   V TGD L + GCGR  F  G    MY  +   L +LPD T V+ GH+Y
Sbjct: 123 NGDRVLTGDALLIRGCGRTDFQSGDPGLMYDHVTQHLFTLPDETLVYPGHDY 174



 Score = 23.0 bits (47), Expect(2) = 2e-04
 Identities = 9/11 (81%), Positives = 10/11 (90%)
 Frame = -3

Query: 219 STIGEEKLYNP 187
           STIGEEK +NP
Sbjct: 180 STIGEEKRWNP 190


>UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Thiomicrospira crunogena XCL-2|Rep:
           Metallo-beta-lactamase superfamily protein -
           Thiomicrospira crunogena (strain XCL-2)
          Length = 229

 Score = 46.4 bits (105), Expect(2) = 2e-04
 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           GH    +T   EG    VFTGDTL +  CGR  F  G    MY +L  IL  LP+ T VF
Sbjct: 112 GHTNNDITYQIEG---AVFTGDTLMVRDCGRTDFQLGDNKAMYHSLTEILFKLPEDTMVF 168

Query: 345 CGHEY 331
             H+Y
Sbjct: 169 PAHDY 173



 Score = 20.6 bits (41), Expect(2) = 2e-04
 Identities = 8/10 (80%), Positives = 9/10 (90%)
 Frame = -3

Query: 219 STIGEEKLYN 190
           STIGEEK +N
Sbjct: 179 STIGEEKQFN 188


>UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3;
           Cystobacterineae|Rep: Myofibrillogenesis regulator 1 -
           Stigmatella aurantiaca DW4/3-1
          Length = 220

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 21/51 (41%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           D++V +GDT+F+ GCGR     G  + MY++L  +L  +PD T+++ GH+Y
Sbjct: 136 DALV-SGDTVFINGCGRCDMRGGNPEDMYRSLSQVLLRVPDETRLWPGHDY 185


>UniRef50_A2FLV6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=2; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 223

 Score = 38.7 bits (86), Expect(2) = 3e-04
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + ++F+GDTLF    GR  F  G   Q+   ++  L  LPD T VF GH
Sbjct: 153 EKLLFSGDTLFKDSIGRSDFPYGDGRQLVSGIVNNLMKLPDDTVVFPGH 201



 Score = 27.5 bits (58), Expect(2) = 3e-04
 Identities = 10/14 (71%), Positives = 13/14 (92%)
 Frame = -3

Query: 219 STIGEEKLYNPFMR 178
           +TIGEE+ YNPF+R
Sbjct: 205 TTIGEERKYNPFIR 218


>UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein;
           n=1; Beggiatoa sp. PS|Rep: Metallo-beta-lactamase family
           protein - Beggiatoa sp. PS
          Length = 229

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 2/68 (2%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRF-FEGT-ADQMYKALITILSSLPDHTKVF 346
           G  CY++       D  + TGDTLF+ GCGR  F G+  +QMY +L  I + LP  T + 
Sbjct: 127 GSACYYL-------DGHLITGDTLFIFGCGRCDFSGSEPEQMYHSLKKIGTELPKETIIH 179

Query: 345 CGHEYTLQ 322
            GH Y  Q
Sbjct: 180 PGHHYAHQ 187


>UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21;
           Actinomycetales|Rep: Beta-lactamase domain protein -
           Mycobacterium sp. (strain KMS)
          Length = 238

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAA 304
           D  +  GDTLFL GCGR  F  G  D M+++L   L+ LP    VF GH Y+ +     +
Sbjct: 157 DGRLVAGDTLFLEGCGRTDFPGGNVDDMFRSL-QALAQLPGDPTVFPGHWYSAEPSDALS 215

Query: 303 HVEPTNENVKAK 268
           +V+ +N   +A+
Sbjct: 216 NVKRSNYVYRAR 227


>UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Hydroxyacylglutathione hydrolase W - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 220

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVE 295
           +F GDTLF+G  GR     G+   ++ ++ T L  LPD T+V+ GH+Y  + +    H +
Sbjct: 152 LFAGDTLFVGSAGRTDLSGGSIKDLHASIRTRLFPLPDDTRVWPGHDYGDRPVSTIGHEK 211

Query: 294 PTNENVKA 271
            TN  ++A
Sbjct: 212 KTNPFMQA 219


>UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15;
           Gammaproteobacteria|Rep: Zn-dependent hydrolase -
           Francisella tularensis subsp. novicida (strain U112)
          Length = 228

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAA 304
           ++++FTGDTL + G GR  F  G +   Y +++  L +LP  T ++ GH+Y        A
Sbjct: 123 ENMLFTGDTLLIRGSGRTDFQNGDSYAAYDSIMNKLMTLPGSTIIYPGHDYNGITSSSVA 182

Query: 303 HVEPTNENVKAK 268
                N  +K K
Sbjct: 183 EERQNNPRLKVK 194


>UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 279

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 19/48 (39%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           VFTGDTL + GCGR  F EG    +Y+ + + + +LP++ +++  H+Y
Sbjct: 174 VFTGDTLLIRGCGRTDFQEGCPRNLYENVHSKIFTLPENFRIYPAHDY 221


>UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=10; Chlorobiaceae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Chlorobium
           tepidum
          Length = 215

 Score = 43.2 bits (97), Expect = 0.004
 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = -3

Query: 468 VFTGDTLFLGGC-GRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           +FTGDTLF+G   G + E  A   Y++L   L  LP  T VF GH+Y    +    H + 
Sbjct: 126 LFTGDTLFVGKVGGTWSEADARLEYRSLHERLMVLPAGTNVFPGHDYGTAPVSTIGHEKT 185

Query: 291 TN 286
           TN
Sbjct: 186 TN 187


>UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein;
           n=6; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Nitrosococcus oceani (strain ATCC 19707 /
           NCIMB 11848)
          Length = 361

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           VFTGD L + GCGR  F  G    +Y ++   L +LP  T V+ GH+Y
Sbjct: 127 VFTGDALLINGCGRTDFQGGDPGTLYDSVTQKLFTLPGETIVYPGHDY 174


>UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: Beta-lactamase domain protein - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 236

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 22/71 (30%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVE 295
           +FTGDTL +  CGR  F  G+A++++ ++  I  +LPD T V+  H+Y  + +      +
Sbjct: 129 IFTGDTLLIRSCGRCDFQGGSAEKLFDSIQKIF-TLPDETLVYPAHDYGGRTVSSIWEEK 187

Query: 294 PTNENVKAKIS 262
             NE + + ++
Sbjct: 188 QFNEMIGSNVN 198


>UniRef50_A0BKZ2 Cluster: Chromosome undetermined scaffold_113,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_113,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 279

 Score = 42.7 bits (96), Expect = 0.005
 Identities = 31/121 (25%), Positives = 58/121 (47%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEP 292
           ++F+GDT+ +   G   +  A   + A +  L    D T +F GH    +   FA  +EP
Sbjct: 160 ILFSGDTILVNNVGEIEDYGA---FFATLQKLRGFHDETLIFPGHLPQQEVFLFAKTLEP 216

Query: 291 TNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKNDPIDTMKAI 112
            N  V+ K+             +P+++ EE++ NP+ R ++L       ++DPI  +K +
Sbjct: 217 DNIVVQNKMGLDN--------LIPTSLIEERMGNPYFRYSQL--NGKVKESDPIKYLKKL 266

Query: 111 R 109
           +
Sbjct: 267 K 267


>UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular
           organisms|Rep: Metallo-beta-lactamase - Methanosarcina
           acetivorans
          Length = 481

 Score = 42.3 bits (95), Expect = 0.006
 Identities = 28/67 (41%), Positives = 36/67 (53%), Gaps = 7/67 (10%)
 Frame = -3

Query: 516 HICYFVTAPEEGND-SVVFTGDTLFLGGCGR--FFEGTADQ----MYKALITILSSLPDH 358
           HI Y V+    G D + VF GDTLF+G  GR   F G A +    +Y +L   L SLPD 
Sbjct: 114 HISYVVSDTSRGPDPTAVFCGDTLFVGDVGRPDLFPGKARELASTLYDSLHKKLLSLPDS 173

Query: 357 TKVFCGH 337
            +V+  H
Sbjct: 174 CEVYPAH 180


>UniRef50_A7CUG8 Cluster: Beta-lactamase domain protein; n=1;
           Opitutaceae bacterium TAV2|Rep: Beta-lactamase domain
           protein - Opitutaceae bacterium TAV2
          Length = 236

 Score = 37.1 bits (82), Expect(2) = 0.008
 Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
 Frame = -3

Query: 465 FTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           F GD LF G  GR     G+++Q+ +++ T + +LP+ T+VF GH
Sbjct: 174 FVGDALFAGSVGRTDLPGGSSEQLARSVRTQIYTLPNETQVFPGH 218



 Score = 24.2 bits (50), Expect(2) = 0.008
 Identities = 8/15 (53%), Positives = 13/15 (86%)
 Frame = -3

Query: 222 PSTIGEEKLYNPFMR 178
           P+T+G+E+  NPF+R
Sbjct: 221 PTTVGKERESNPFVR 235


>UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione
           hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Similar to hydroxyacylglutathione hydrolase - Candidatus
           Kuenenia stuttgartiensis
          Length = 210

 Score = 39.9 bits (89), Expect(2) = 0.008
 Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           ++ +F GDTLF G  GR   + G+ D +  ++ T L +L DH  V+ GH
Sbjct: 146 NNAIFAGDTLFAGSVGRTDLYGGSHDTLINSVKTRLFTLEDHVLVYPGH 194



 Score = 21.4 bits (43), Expect(2) = 0.008
 Identities = 7/12 (58%), Positives = 11/12 (91%)
 Frame = -3

Query: 219 STIGEEKLYNPF 184
           +TIG+EK +NP+
Sbjct: 198 TTIGKEKKHNPY 209


>UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Rep:
           Beta-lactamase-like - Desulfitobacterium hafniense
           (strain DCB-2)
          Length = 205

 Score = 39.5 bits (88), Expect(2) = 0.008
 Identities = 20/46 (43%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + +GDTLF G  GR  F  G+ D++ K+++  L  LP+ TKV+ GH
Sbjct: 143 LLSGDTLFDGSIGRTDFPGGSYDELIKSVVKKLLVLPEDTKVYPGH 188



 Score = 21.8 bits (44), Expect(2) = 0.008
 Identities = 8/14 (57%), Positives = 11/14 (78%)
 Frame = -3

Query: 219 STIGEEKLYNPFMR 178
           +TIG EK  NPF++
Sbjct: 192 TTIGREKRENPFLQ 205


>UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1;
           Acinetobacter baumannii ATCC 17978|Rep: Putative
           uncharacterized protein - Acinetobacter baumannii
           (strain ATCC 17978 / NCDC KC 755)
          Length = 186

 Score = 37.9 bits (84), Expect(2) = 0.008
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           GH+ ++       N  +++TGD LF G  GR  F  G  +Q+ +++     SLPD T+  
Sbjct: 108 GHVMFY-----NKNHGLLWTGDVLFKGSIGRTDFPRGNHEQLIESIQRECFSLPDETQFI 162

Query: 345 CGH 337
            GH
Sbjct: 163 SGH 165



 Score = 23.4 bits (48), Expect(2) = 0.008
 Identities = 9/13 (69%), Positives = 11/13 (84%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           STIG EK +NPF+
Sbjct: 169 STIGYEKQFNPFV 181


>UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Bacillus|Rep: Hydroxyacylglutathione hydrolase -
           Bacillus amyloliquefaciens
          Length = 230

 Score = 41.9 bits (94), Expect = 0.009
 Identities = 18/48 (37%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFE--GTADQMYKALITILSSLPDHTKVFCGHEY 331
           +FTGDT+F  GCG   +   +A+ M+ ++  I +S+P H +V+ GH +
Sbjct: 141 LFTGDTVFTEGCGICGDRGSSAEDMFHSIQRIKASIPPHVRVYPGHSF 188


>UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 214

 Score = 41.9 bits (94), Expect = 0.009
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAA 304
           D  +FTGDTLF+G  GR     G+  ++ ++L T + +LP  T V+ GH+Y  +      
Sbjct: 141 DGNLFTGDTLFVGAVGRTDLPGGSFGELIQSLKTKIVTLPPDTVVWPGHDYGDRPFSTVK 200

Query: 303 HVEPTN 286
           H   TN
Sbjct: 201 HEMKTN 206


>UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase
           domain protein - Victivallis vadensis ATCC BAA-548
          Length = 205

 Score = 39.1 bits (87), Expect(2) = 0.011
 Identities = 21/50 (42%), Positives = 30/50 (60%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +DS VFTGD LF+ GC  F    + +MY +L+  +  L D   V+ GH+Y
Sbjct: 125 DDSAVFTGDVLFV-GCIGFCR--SKEMYNSLMKKILPLADSLVVYSGHDY 171



 Score = 21.8 bits (44), Expect(2) = 0.011
 Identities = 8/17 (47%), Positives = 11/17 (64%)
 Frame = -3

Query: 216 TIGEEKLYNPFMRVTEL 166
           T+GEEK  NP++    L
Sbjct: 178 TLGEEKKLNPYLNCHSL 194


>UniRef50_Q59X44 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 116

 Score = 41.5 bits (93), Expect = 0.011
 Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 77  KEIYLNVSFSSRIAFIVSIGSFLPV*F*TANSVTLMNGLYNFSSPIVEGTVGFPW-FRLS 253
           K ++  + F  R   I+S G   PV   T  SV+ +NGL   SSPIV   V   W  + S
Sbjct: 31  KAMFYILFFMVRNLSIISSGRVNPVSLITWGSVSFINGLNCNSSPIVNLPVVCSWDLQYS 90

Query: 254 CDQLILALTFSLVGST*AANFKFCKVYSWP 343
            +  I +L      +T   NF F  VYSWP
Sbjct: 91  ANSFIASLL-----NTVCENFTFDLVYSWP 115


>UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3;
           Deltaproteobacteria|Rep: Beta-lactamase-like - delta
           proteobacterium MLMS-1
          Length = 213

 Score = 39.9 bits (89), Expect(2) = 0.014
 Identities = 28/65 (43%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G IC + TAP       +FTGDTLF+GG GR  F  G    +  +L   L  LP  T V+
Sbjct: 134 GGICLY-TAPH------LFTGDTLFVGGVGRTDFPGGDTATLVNSLQQRLLKLPPETVVW 186

Query: 345 CGHEY 331
            GH Y
Sbjct: 187 PGHGY 191



 Score = 20.6 bits (41), Expect(2) = 0.014
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           STIGEE   NP++
Sbjct: 196 STIGEEARDNPYL 208


>UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3;
           Dehalococcoides|Rep: Beta-lactamase domain protein -
           Dehalococcoides sp. BAV1
          Length = 217

 Score = 38.3 bits (85), Expect(2) = 0.023
 Identities = 21/46 (45%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           +F+GDTLF  G GR  F E   + + + +I  L SLP  T VF GH
Sbjct: 156 LFSGDTLFNSGIGRSDFEESDTEALRQNIINRLLSLPPETLVFPGH 201



 Score = 21.4 bits (43), Expect(2) = 0.023
 Identities = 8/13 (61%), Positives = 11/13 (84%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           +TIG+EK  NPF+
Sbjct: 205 TTIGKEKTGNPFI 217


>UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 226

 Score = 40.3 bits (90), Expect = 0.026
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTADQ--MYKALITILSSLPDHTKVF 346
           G +C++   PE      + TGD LF+G CG      +D   M   L   L SLP+ T+V+
Sbjct: 131 GCVCWY--GPEA---KALITGDVLFVGSCGGVSYPGSDPAAMVHTLQRKLGSLPEETRVY 185

Query: 345 CGHEY 331
            GH+Y
Sbjct: 186 PGHDY 190


>UniRef50_A1ID45 Cluster: Beta-lactamase-like; n=3; Bacteria|Rep:
           Beta-lactamase-like - Candidatus Desulfococcus
           oleovorans Hxd3
          Length = 210

 Score = 40.3 bits (90), Expect = 0.026
 Identities = 22/49 (44%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           D   F GDTLF G  GR  F  G  D +  A+ T L  L D   V+CGH
Sbjct: 143 DKKAFVGDTLFAGSIGRTDFPGGDFDTLISAIQTKLFPLGDDVTVYCGH 191


>UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n=1;
           unknown|Rep: UPI00015BCB57 UniRef100 entry - unknown
          Length = 217

 Score = 39.9 bits (89), Expect = 0.035
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + + +  GDTLF GG GR     G+ + + K+L  I S LP  T V CGH
Sbjct: 148 SQNTLIAGDTLFKGGVGRTDLPGGSWEDLSKSLKKIFSILPKDTHVICGH 197


>UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein;
           n=1; Porphyromonas gingivalis|Rep:
           Metallo-beta-lactamase family protein - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 214

 Score = 39.9 bits (89), Expect = 0.035
 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           GH+ ++   P+      VFTGD LF G  GR   + G+ + + K++ T L  LPD T V+
Sbjct: 140 GHLAFY--CPQA---QAVFTGDALFAGDMGRTDLWGGSYELLKKSIRTELLPLPDDTVVY 194

Query: 345 CGH 337
            GH
Sbjct: 195 PGH 197


>UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37;
           Actinomycetales|Rep: Beta-lactamase-like - Frankia sp.
           (strain CcI3)
          Length = 216

 Score = 39.9 bits (89), Expect = 0.035
 Identities = 26/63 (41%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFFEGTAD--QMYKALITILSSLPDHTKVF 346
           G IC F    E   D V+F+GDTLF GG G      +D   +  ++ T L +LP HT V 
Sbjct: 136 GGICLF---GEINGDPVLFSGDTLFRGGPGATGRSYSDFPTILASIRTRLLTLPAHTVVH 192

Query: 345 CGH 337
            GH
Sbjct: 193 TGH 195


>UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium
           phytofermentans ISDg|Rep: Beta-lactamase-like -
           Clostridium phytofermentans ISDg
          Length = 216

 Score = 39.9 bits (89), Expect = 0.035
 Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G +CY++  P+E    ++ +GDTLF    GR  F  G ++ + K++   L +LP   KV+
Sbjct: 136 GSVCYYI--PDE---QILLSGDTLFFESVGRTDFPTGNSEVLVKSINERLFTLPKEVKVY 190

Query: 345 CGH 337
            GH
Sbjct: 191 PGH 193


>UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter
           sp. BAL39|Rep: Rhodanese-like protein - Pedobacter sp.
           BAL39
          Length = 459

 Score = 39.9 bits (89), Expect = 0.035
 Identities = 15/21 (71%), Positives = 17/21 (80%)
 Frame = -3

Query: 489 EEGNDSVVFTGDTLFLGGCGR 427
           + GND  VFTGDTLF+G CGR
Sbjct: 123 QNGNDKAVFTGDTLFIGDCGR 143


>UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 235

 Score = 39.9 bits (89), Expect = 0.035
 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCG--RFFEGTADQMYKALITILSSLPDHTKVF 346
           G +C+FV       D  +FTGDT+F+ GCG      G A  M+ ++  I + +   TK++
Sbjct: 136 GGMCFFV-------DGSLFTGDTIFMEGCGICSNLGGDAGDMFHSINRIKAEVSHDTKMY 188

Query: 345 CGH 337
            GH
Sbjct: 189 SGH 191


>UniRef50_Q5FRS6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Gluconobacter oxydans|Rep:
           Metallo-beta-lactamase superfamily protein -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 245

 Score = 33.5 bits (73), Expect(2) = 0.040
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           V  GDTLF G  GR  F  G +  +   +   L +L D T V CGH
Sbjct: 182 VLAGDTLFRGTVGRTDFAYGDSQALVDGIRRHLLTLSDDTVVLCGH 227



 Score = 25.4 bits (53), Expect(2) = 0.040
 Identities = 9/15 (60%), Positives = 13/15 (86%)
 Frame = -3

Query: 225 VPSTIGEEKLYNPFM 181
           +P+TIGEE+  NPF+
Sbjct: 229 MPTTIGEERRTNPFL 243


>UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5;
           Bacteroides|Rep: Putative metallo-beta-lactamase -
           Bacteroides fragilis
          Length = 212

 Score = 34.3 bits (75), Expect(2) = 0.040
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           D+ +F+GD LF G  GR     G  D++ + + + L  LP+ T V+ GH
Sbjct: 147 DNCMFSGDVLFQGSIGRADLAGGNFDELKEHICSRLFVLPNETIVYPGH 195



 Score = 24.6 bits (51), Expect(2) = 0.040
 Identities = 10/15 (66%), Positives = 11/15 (73%)
 Frame = -3

Query: 222 PSTIGEEKLYNPFMR 178
           P+TIG EK  NPF R
Sbjct: 198 PTTIGIEKAENPFFR 212


>UniRef50_Q9JIL1 Cluster: Rsp29-like protein; n=1; Mus musculus|Rep:
           Rsp29-like protein - Mus musculus (Mouse)
          Length = 56

 Score = 39.5 bits (88), Expect = 0.046
 Identities = 16/25 (64%), Positives = 19/25 (76%)
 Frame = -3

Query: 162 VQNHTGKNDPIDTMKAIRLEKDTFK 88
           VQ H G+ DP+ TM+AIR EKD FK
Sbjct: 28  VQQHAGETDPVTTMRAIRREKDQFK 52


>UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;
           n=36; cellular organisms|Rep: ETHE1 protein,
           mitochondrial precursor - Homo sapiens (Human)
          Length = 254

 Score = 39.5 bits (88), Expect = 0.046
 Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = -3

Query: 480 ND-SVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           ND S+ FTGD L + GCGR  F +G A  +Y ++   + +LP    ++  H+Y
Sbjct: 145 NDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDY 197


>UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein;
           n=1; Treponema denticola|Rep: Metallo-beta-lactamase
           family protein - Treponema denticola
          Length = 213

 Score = 39.1 bits (87), Expect = 0.060
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGRF-FEGTADQMYKALITILSSLPDHTKVFC 343
           G +C++    EE    V+F+GDTLF    GR    G  DQ  KA +  L +LPD T V+ 
Sbjct: 141 GSVCFW---NEEAK--VLFSGDTLFYRSHGRTDLLGGDDQKMKASLKSLLNLPDDTTVYP 195

Query: 342 GH 337
           GH
Sbjct: 196 GH 197


>UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2;
           Sulfolobus|Rep: Putative uncharacterized protein -
           Sulfolobus solfataricus
          Length = 209

 Score = 39.1 bits (87), Expect = 0.060
 Identities = 18/44 (40%), Positives = 26/44 (59%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           +FTGDTLF G  GR   G ++++ +  +  L  LPD   V+ GH
Sbjct: 144 IFTGDTLFYGTVGRTDLGGSEKLLRESLEKLKKLPDEIIVYPGH 187


>UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1;
           Aquifex aeolicus|Rep: Uncharacterized protein aq_2135 -
           Aquifex aeolicus
          Length = 211

 Score = 35.5 bits (78), Expect(2) = 0.068
 Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFF--EGTADQMYKALITILSSLPDHTKVFCGH 337
           V+  GD LF G  GR+    G   ++ K++  +L+ LP  T V CGH
Sbjct: 143 VLIAGDLLFKGSVGRWDLPGGNLVELKKSVKRVLTELPQDTLVICGH 189



 Score = 22.6 bits (46), Expect(2) = 0.068
 Identities = 7/12 (58%), Positives = 11/12 (91%)
 Frame = -3

Query: 219 STIGEEKLYNPF 184
           +TIG+E+ +NPF
Sbjct: 193 TTIGQERAFNPF 204


>UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep:
           Beta-lactamase-like - Moorella thermoacetica (strain
           ATCC 39073)
          Length = 207

 Score = 37.1 bits (82), Expect(2) = 0.069
 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + +VFTGDTLF G  GR  F  G+  Q+  ++   L +L D  +V+ GH
Sbjct: 142 EGLVFTGDTLFAGSIGRTDFPGGSYSQLISSIKEKLFTLDDALEVYPGH 190



 Score = 21.0 bits (42), Expect(2) = 0.069
 Identities = 8/12 (66%), Positives = 10/12 (83%)
 Frame = -3

Query: 219 STIGEEKLYNPF 184
           STIG E++ NPF
Sbjct: 194 STIGAERVDNPF 205


>UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1;
           Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain
           protein - Shewanella sediminis HAW-EB3
          Length = 354

 Score = 38.7 bits (86), Expect = 0.080
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 2/49 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYT 328
           VFTGDTL LGG GR     G  +++Y +L   L  L    KV+  H Y+
Sbjct: 127 VFTGDTLLLGGTGRTDLPSGDPERLYDSLFNGLLKLSADLKVYPAHAYS 175


>UniRef50_A4AWZ7 Cluster: Putative uncharacterized protein; n=2;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Alteromonas macleodii 'Deep ecotype'
          Length = 284

 Score = 38.7 bits (86), Expect = 0.080
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 4/53 (7%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           D  +F GDT+F    G     F  G+A+Q+Y  +    + LPD T V+ GH+Y
Sbjct: 153 DGKIFVGDTMFAPNLGTARCDFPGGSAEQLYNTIQRFFT-LPDDTTVYLGHDY 204


>UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Clostridium|Rep: Hydroxyacylglutathione hydrolase -
           Clostridium tetani
          Length = 201

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           ++++FTGDTLF G  GR  F+ G  + + K +   + ++P+ T V  GH
Sbjct: 137 ENIIFTGDTLFEGSIGRTDFYGGNFEILIKNIKEKILTIPEDTLVLPGH 185


>UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus torques ATCC 27756
          Length = 207

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G  CY++     G + V+F+GDTLF    GR     G+  ++ +++   L  LP+ T+V+
Sbjct: 134 GGCCYYI-----GEEHVLFSGDTLFHNSIGRTDLPTGSGSELVRSVREKLLVLPEDTRVY 188

Query: 345 CGH 337
            GH
Sbjct: 189 PGH 191


>UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1;
           Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain
           protein - Geobacter uraniumreducens Rf4
          Length = 233

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCG--RFFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +FTGDT+F+ GCG      G+A  M++++  I  ++  H  VF GH Y
Sbjct: 144 LFTGDTVFVEGCGICTTEGGSASGMFESIQRIKRTVEPHVSVFPGHCY 191


>UniRef50_A3SZ22 Cluster: Beta-lactamase-like; n=6;
           Proteobacteria|Rep: Beta-lactamase-like - Sulfitobacter
           sp. NAS-14.1
          Length = 306

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 4/52 (7%)
 Frame = -3

Query: 474 SVVFTGDTLFL--GGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +  FTGDTLF+  GG  R  F  G A ++Y ++  +L SLPD  ++F  H+Y
Sbjct: 177 NAAFTGDTLFMPDGGSARADFPGGDAGELYDSIQKVL-SLPDDMRLFMCHDY 227


>UniRef50_A0NAW9 Cluster: ENSANGP00000031703; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000031703 - Anopheles gambiae
           str. PEST
          Length = 144

 Score = 38.3 bits (85), Expect = 0.11
 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + +GD LF G  GR   F+   DQ+  ++ T L  LP+ T+VF GH
Sbjct: 99  IISGDVLFEGSIGRTDLFKANFDQLIDSIKTKLLILPEDTQVFSGH 144


>UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7;
           Bacteria|Rep: Beta-lactamase-like precursor -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 251

 Score = 34.3 bits (75), Expect(2) = 0.12
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 6/66 (9%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDS-VVFTGDTLFLGGCGR-FFEG----TADQMYKALITILSSLPDHTK 352
           IC  V     G++   V TGDTLF+G  GR    G     A Q++  L   L +LP   +
Sbjct: 119 ICLLVRDLRRGDEPWFVITGDTLFVGAAGRPDLAGREREMAGQLHDTLHAKLLTLPADLE 178

Query: 351 VFCGHE 334
           +F GH+
Sbjct: 179 IFPGHQ 184



 Score = 23.0 bits (47), Expect(2) = 0.12
 Identities = 11/25 (44%), Positives = 17/25 (68%)
 Frame = -3

Query: 237 GKPTVPSTIGEEKLYNPFMRVTELA 163
           GKP+  STIG E+ +NP + ++  A
Sbjct: 195 GKPS--STIGFERRFNPMLSMSREA 217


>UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 207

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKAL-ITILSSLPDHTKV 349
           G  CY++    E N+ ++F+GDTLF G  GR  F  G+  ++ K++   +L  LPD T V
Sbjct: 136 GSGCYYL----EDNE-ILFSGDTLFHGSRGRTDFPGGSESEIMKSIREKLLKKLPDETAV 190

Query: 348 FCGH 337
             GH
Sbjct: 191 LPGH 194


>UniRef50_A2QJI7 Cluster: Catalytic activity:; n=3; Aspergillus|Rep:
           Catalytic activity: - Aspergillus niger
          Length = 360

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 29/94 (30%), Positives = 48/94 (51%), Gaps = 4/94 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAH 301
           VFTGD++F    G     F  G A  +Y+ +  +L+ LP+H K++ GH+Y       AA 
Sbjct: 173 VFTGDSIFNPDVGSARCDFPHGDARALYQTMRKLLA-LPEHVKLYTGHDYPPAVEGGAAT 231

Query: 300 VEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEK 199
              +    KA ++  +D++ + K     T GEE+
Sbjct: 232 TTTSVREPKAFVT-VKDQKERNKHVKEGT-GEEE 263


>UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4;
           Deinococci|Rep: Beta-lactamase-like protein -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 219

 Score = 37.5 bits (83), Expect = 0.18
 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           GH+ +   + EE     V  GDTLF G  GR     G   Q+   +   L SLPD T ++
Sbjct: 142 GHVVFVAQSGEE--PGFVVAGDTLFQGSIGRTDLPGGNHPQLIAGIRRELLSLPDETAIY 199

Query: 345 CGH 337
            GH
Sbjct: 200 PGH 202


>UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep:
           Metallo-beta-lactamase family protein - Lentisphaera
           araneosa HTCC2155
          Length = 222

 Score = 37.5 bits (83), Expect = 0.18
 Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           D+ +FTGDT+F+ GCGR     G  + MY  L  I ++      V  GH+Y
Sbjct: 128 DNHLFTGDTVFVYGCGRCNLRGGDPEAMYHTLNKIGTNFDPSMTVLPGHDY 178


>UniRef50_A3L9H1 Cluster: Putative uncharacterized protein; n=1;
           Pseudomonas aeruginosa 2192|Rep: Putative
           uncharacterized protein - Pseudomonas aeruginosa 2192
          Length = 270

 Score = 37.5 bits (83), Expect = 0.18
 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 7/108 (6%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQN-- 319
           N+ VVF GDTLF    G     F  G+A  +Y+++  +L SLP H ++   H+Y  ++  
Sbjct: 154 NNEVVFVGDTLFPPDVGTARCDFPGGSAKTLYRSIQRLL-SLPAHVQMMMCHDYPPRDRA 212

Query: 318 -LKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMR 178
            +      E  + N+ A+   S+    + +     T+   +L  P MR
Sbjct: 213 PIVECTVAEQRSTNIHARSGISEAEFIEMRTQRDRTLPAPRLLGPSMR 260


>UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;
           n=15; Actinomycetales|Rep: Uncharacterized protein
           Rv2581c/MT2658 - Mycobacterium tuberculosis
          Length = 224

 Score = 34.7 bits (76), Expect(2) = 0.20
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G + + V      +  +VFTGDTLF    GR     G+   + ++++  L  L D T V 
Sbjct: 141 GSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSIVDKLLVLDDSTVVL 200

Query: 345 CGH 337
            GH
Sbjct: 201 PGH 203



 Score = 21.8 bits (44), Expect(2) = 0.20
 Identities = 7/13 (53%), Positives = 11/13 (84%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           +TIG E+ +NPF+
Sbjct: 207 TTIGAERRFNPFL 219


>UniRef50_Q031I9 Cluster: Zn-dependent hydrolase, including
           glyoxylase; n=3; Lactococcus lactis|Rep: Zn-dependent
           hydrolase, including glyoxylase - Lactococcus lactis
           subsp. cremoris (strain SK11)
          Length = 210

 Score = 31.9 bits (69), Expect(2) = 0.20
 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
 Frame = -3

Query: 489 EEGNDSVVFTGDTLFLGGCGRFF--EGTADQMYKALITILSSLPDHTKVFCGH 337
           E   DS +F+GD LF    GR+    G   Q+ +++   L  L +H +V  GH
Sbjct: 141 ESEGDSCLFSGDALFKNAIGRWDLPTGNQAQLLESIRDQLFRLDNHIRVLPGH 193



 Score = 24.6 bits (51), Expect(2) = 0.20
 Identities = 9/14 (64%), Positives = 12/14 (85%)
 Frame = -3

Query: 219 STIGEEKLYNPFMR 178
           +TIG EKL+NPF +
Sbjct: 197 TTIGAEKLHNPFFQ 210


>UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2;
           Clostridiaceae|Rep: Beta-lactamase domain protein -
           Alkaliphilus metalliredigens QYMF
          Length = 206

 Score = 35.5 bits (78), Expect(2) = 0.20
 Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + VVFTGDTLF    GR     G  DQ+  ++ + L +L D   V  GH
Sbjct: 141 EGVVFTGDTLFANSIGRSDLEGGNYDQLIASIQSKLMTLDDELTVLPGH 189



 Score = 21.0 bits (42), Expect(2) = 0.20
 Identities = 7/14 (50%), Positives = 12/14 (85%)
 Frame = -3

Query: 219 STIGEEKLYNPFMR 178
           STIG E++ NP+++
Sbjct: 193 STIGIERMTNPYIK 206


>UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Trypanosoma brucei|Rep:
           Hydroxyacylglutathione hydrolase, putative - Trypanosoma
           brucei
          Length = 464

 Score = 37.1 bits (82), Expect = 0.24
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 15/83 (18%)
 Frame = -3

Query: 492 PEEGNDS--VVFTGDTLFLGGCGRFFEGTADQMYKALITILSS-------------LPDH 358
           P+EG      +FTGD +F GGCG  FE T+       + I ++               D 
Sbjct: 276 PKEGEPQRLALFTGDCVFCGGCGALFEATSVDETLETVDIFNNNRTWVHPATGDIIHTDD 335

Query: 357 TKVFCGHEYTLQNLKFAAHVEPT 289
             ++ GHEYT ++L     V+ T
Sbjct: 336 VLIYVGHEYTERSLDMILSVQRT 358


>UniRef50_Q4WA79 Cluster: Metallo-beta-lactamase domain protein,
           putative; n=9; Pezizomycotina|Rep:
           Metallo-beta-lactamase domain protein, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 298

 Score = 36.7 bits (81), Expect = 0.32
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLK 313
           VF GD +F    G     F  G+A+ +Y++   +L  LPDH KV+ GH+Y  +  K
Sbjct: 165 VFCGDLIFHSDIGTARCDFPGGSANNLYRSGRKVLG-LPDHVKVWTGHDYPPEGRK 219


>UniRef50_Q9PFB0 Cluster: Beta-lactamase hydrolase-like protein;
           n=42; Proteobacteria|Rep: Beta-lactamase hydrolase-like
           protein - Xylella fastidiosa
          Length = 431

 Score = 36.7 bits (81), Expect = 0.32
 Identities = 20/49 (40%), Positives = 30/49 (61%), Gaps = 4/49 (8%)
 Frame = -3

Query: 465 FTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           F  DT+F+   G     F  G+A  ++ ++ TILS LPD T++F GH+Y
Sbjct: 300 FVHDTIFMPDAGTARADFPGGSARALWSSIQTILS-LPDETRLFTGHDY 347


>UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium
           difficile|Rep: Putative hydrolase - Clostridium
           difficile (strain 630)
          Length = 204

 Score = 34.7 bits (76), Expect(2) = 0.34
 Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           +FTGDTLF G  GR   + G  +QM K+L   L    D  +V+ GH
Sbjct: 144 MFTGDTLFAGSIGRTDLYSGDFNQMEKSL-KKLCKYEDAVRVYPGH 188



 Score = 21.0 bits (42), Expect(2) = 0.34
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           ST+G EK  NP+M
Sbjct: 192 STLGVEKKTNPYM 204


>UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 617

 Score = 36.3 bits (80), Expect = 0.43
 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 8/67 (11%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEG------TADQMYKALITILSSLPDH 358
           +C  V +  +    ++FTGDTLF+G  GR    EG       A   Y     +LS LPD 
Sbjct: 112 MCGLVFSEGDDQPKMIFTGDTLFVGSVGRPDLLEGKMTAATLASMSYDTWHNVLSKLPDT 171

Query: 357 TKVFCGH 337
             V   H
Sbjct: 172 VAVLPAH 178


>UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep:
           Orf c06001 protein - Sulfolobus solfataricus
          Length = 247

 Score = 36.3 bits (80), Expect = 0.43
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRF---FEGTADQMYKALITILSSLPDHTKVFCGH 337
           + TGDTLF+GG GR     E   + +Y +L   L  LPD+ +++  H
Sbjct: 139 ILTGDTLFVGGLGRIDIGGENAEENLYYSLAK-LKELPDYVEIYPAH 184


>UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2;
           Bacteria|Rep: Beta-lactamase domain protein -
           Desulfotomaculum reducens MI-1
          Length = 205

 Score = 31.1 bits (67), Expect(2) = 0.44
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           +F+GDTLF    GR  F  G+   +  ++ + L  L D TKV+ GH
Sbjct: 144 LFSGDTLFAQSIGRSDFPGGSHSTLIGSIKSKLLVLSDETKVYPGH 189



 Score = 24.2 bits (50), Expect(2) = 0.44
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = -3

Query: 219 STIGEEKLYNPF 184
           STIG+EK +NPF
Sbjct: 193 STIGQEKRHNPF 204


>UniRef50_UPI000049880A Cluster: metallo-beta-lactamase superfamily
           protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           metallo-beta-lactamase superfamily protein - Entamoeba
           histolytica HM-1:IMSS
          Length = 217

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           ++ +V  GDTLF G  GR   + G+  Q+  ++  +L SLP +T V  GH
Sbjct: 150 DEEIVINGDTLFAGSYGRTDLWGGSFAQLKASIKNVLFSLPLNTIVVTGH 199


>UniRef50_Q1ZAD4 Cluster: Probable metallo-beta-lactamase
           superfamily protein; n=1; Photobacterium profundum
           3TCK|Rep: Probable metallo-beta-lactamase superfamily
           protein - Photobacterium profundum 3TCK
          Length = 260

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
 Frame = -3

Query: 468 VFTGDTLFLG--GCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQN 319
           +F GDTLF    G GR  F  G+A  +Y++ I+ L  LP+ T V+  H+Y  +N
Sbjct: 147 IFVGDTLFAPKRGTGRADFPGGSAKDLYRS-ISRLFELPEDTDVYLCHDYPSEN 199


>UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1;
           Fulvimarina pelagi HTCC2506|Rep: Putative
           uncharacterized protein - Fulvimarina pelagi HTCC2506
          Length = 289

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 4/50 (8%)
 Frame = -3

Query: 468 VFTGDTLFLGGCG----RFFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +F+GDTLF  GCG    R   G +  ++++L  +  +LP   +++ GH Y
Sbjct: 155 LFSGDTLFSEGCGLSDPRNGGGDSGALFRSLDALRRTLPAECRIYPGHRY 204


>UniRef50_A6L981 Cluster: Metallo-beta-lactamase family protein;
           n=1; Parabacteroides distasonis ATCC 8503|Rep:
           Metallo-beta-lactamase family protein - Parabacteroides
           distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 212

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           V  GD+LF G  GR   + G  D +  A+   L SLPD T V+ GH
Sbjct: 151 VIVGDSLFAGSIGRTDLWGGNQDILLAAIKDKLLSLPDETVVYPGH 196


>UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 208

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           GH C  +    E   +++F+GDTLF  G GR     G    +Y +++  L  LP  T V+
Sbjct: 128 GHTCGSICIQVE---NLLFSGDTLFKFGYGRVDLPNGNFSDIYNSIVEKLFILPGETIVY 184

Query: 345 CGH 337
            GH
Sbjct: 185 PGH 187


>UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_440_31929_31255 - Giardia lamblia
           ATCC 50803
          Length = 224

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           VVFTGDT+F    GR  F  G++ Q+  ++  I   L D  +++ GH +
Sbjct: 158 VVFTGDTIFANSVGRTDFPGGSSKQLKASVKRIYKELSDDFRIYPGHNH 206


>UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10;
           Bacillaceae|Rep: Uncharacterized protein yqgX - Bacillus
           subtilis
          Length = 211

 Score = 35.9 bits (79), Expect = 0.56
 Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           +V +GD LF GG GR     G  + +  ++   L +LP+HT V  GH
Sbjct: 144 LVISGDVLFQGGIGRTDLIGGNQETLLTSIHEKLLTLPEHTLVLSGH 190


>UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas sp.
           JS666|Rep: Beta-lactamase-like - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 346

 Score = 35.5 bits (78), Expect = 0.74
 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           D  VFTGDTL +GG GR     G  + +Y +L   L  L     V+  H+Y
Sbjct: 121 DDRVFTGDTLLIGGTGRTDLPTGDPEALYDSLFGRLLKLDPALLVYPAHDY 171


>UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1;
           Clostridium thermocellum ATCC 27405|Rep:
           Beta-lactamase-like protein - Clostridium thermocellum
           (strain ATCC 27405 / DSM 1237)
          Length = 201

 Score = 35.5 bits (78), Expect = 0.74
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           VVFTGDTLF  G GR  F +G    +  ++   L  L D+  V+ GH
Sbjct: 141 VVFTGDTLFCMGIGRTDFPDGDLSTLLDSIKNKLMKLDDNVVVYPGH 187


>UniRef50_Q7RF44 Cluster: Putative uncharacterized protein PY04866;
           n=5; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
           protein PY04866 - Plasmodium yoelii yoelii
          Length = 955

 Score = 35.5 bits (78), Expect = 0.74
 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
 Frame = -3

Query: 360 HTKVFCGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTV-PSTIGEEKLYNPF 184
           H K F  H   L NLKFA  V      +KAK   +  R   G+ T   + + + KL N F
Sbjct: 309 HEKKFLKHICKLYNLKFATKVLTKRNIIKAKGQSTVGRSTSGRTTSGTNRLNKTKLQNNF 368

Query: 183 MRVTELAVQNH----TGK--NDPIDTMKAIRLEKDTFK*ISFYINKKN 58
           + ++ L  +N     T K  N+ I  ++ +  +K+    I  + N KN
Sbjct: 369 LLISRLWRRNAYIEVTNKIYNEKIKDLRNLNEDKNGNDPICDFENGKN 416


>UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_7,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 489

 Score = 35.5 bits (78), Expect = 0.74
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
 Frame = -3

Query: 504 FVTAPEEGNDSVVFTGDTLFLGGCGR---------FFEGTADQMYKALITILSSLPDHTK 352
           F+   EEG    ++TGDTLFLG  GR              A  +Y +L   +  LPD   
Sbjct: 162 FLLYDEEGKQHSIYTGDTLFLGEVGRPDLAVKSDVTQYDLASLLYASLKQKILGLPDDVI 221

Query: 351 VFCGH 337
           VF GH
Sbjct: 222 VFPGH 226


>UniRef50_Q2UI96 Cluster: Zn-dependent hydrolases; n=4;
           Pezizomycotina|Rep: Zn-dependent hydrolases -
           Aspergillus oryzae
          Length = 399

 Score = 35.5 bits (78), Expect = 0.74
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 4/50 (8%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           VF GD+LF    G     F  G+A  ++ +   +LS LPDH K++ GH+Y
Sbjct: 266 VFCGDSLFHADIGTARCDFPGGSAHSLFNSGRKLLS-LPDHVKIWTGHDY 314


>UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 468

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 7/66 (10%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR-------FFEGTADQMYKALITILSSLPDHT 355
           ICY  T   +     +F+GD LF+G  GR        F   A ++Y++L   ++ LPD  
Sbjct: 126 ICYDETRSHD-LPWFIFSGDCLFVGSVGRPDLLGENAFNFLAKELYQSLFVRIAHLPDSV 184

Query: 354 KVFCGH 337
           +VF  H
Sbjct: 185 EVFPAH 190


>UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121;
           Proteobacteria|Rep: Beta-lactamase-like - Mesorhizobium
           sp. (strain BNC1)
          Length = 312

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 9/126 (7%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAA- 304
           VF GDTLF+   G     F  G A Q+Y++ I  L  LPD  ++F  H+Y      + A 
Sbjct: 183 VFPGDTLFMPDYGTARCDFPGGDARQLYRS-IKRLFQLPDEARLFLCHDYKAPGRDYFAW 241

Query: 303 ----HVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPFMRVTELAVQNHTGKND 136
                 E T  N+  +   S+D   + +    +T+   KL  P ++V   A +    +++
Sbjct: 242 ETTVGAERTG-NIHVREGVSEDEFYKMRTERDATLAMPKLILPSVQVNMRAGRLPPAEDN 300

Query: 135 PIDTMK 118
            +  +K
Sbjct: 301 GVQYLK 306


>UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1;
           Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein
           - Roseobacter sp. AzwK-3b
          Length = 306

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 20/53 (37%), Positives = 30/53 (56%), Gaps = 4/53 (7%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           D   F  DTL     G     F  G+++++Y +L  IL+ LPD T++F GH+Y
Sbjct: 166 DDAAFVHDTLMHVDVGTSRADFPGGSSNELYDSLQAILA-LPDQTRLFIGHDY 217


>UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 215

 Score = 35.1 bits (77), Expect = 0.98
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           +F GDT+F G  GR  F  G+ D++ +++   + +LP  T V+ GH
Sbjct: 153 IFVGDTIFAGSIGRTDFPGGSHDRLIRSVKEKIFTLPGDTLVYPGH 198


>UniRef50_Q314Q9 Cluster: Metallo-beta-lactamase family protein;
           n=3; Desulfovibrio|Rep: Metallo-beta-lactamase family
           protein - Desulfovibrio desulfuricans (strain G20)
          Length = 208

 Score = 29.9 bits (64), Expect(2) = 0.98
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           VF GD LF    GR  F  G +  +  ++   + SLPD T V+ GH
Sbjct: 142 VFVGDLLFHRSVGRTDFPGGDSATLLNSVKKAIFSLPDTTVVYPGH 187



 Score = 24.2 bits (50), Expect(2) = 0.98
 Identities = 8/14 (57%), Positives = 12/14 (85%)
 Frame = -3

Query: 225 VPSTIGEEKLYNPF 184
           + +T+G+EKL NPF
Sbjct: 189 IETTVGDEKLNNPF 202


>UniRef50_Q4JCD2 Cluster: Conserved protein; n=1; Sulfolobus
           acidocaldarius|Rep: Conserved protein - Sulfolobus
           acidocaldarius
          Length = 198

 Score = 31.5 bits (68), Expect(2) = 1.3
 Identities = 17/46 (36%), Positives = 23/46 (50%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +FTGDTLF    GR+  G   +  K  +  L  L D   V+ GH +
Sbjct: 133 LFTGDTLFNENIGRYDLGGDREYLKKSLRRLMDLEDLLNVYPGHGF 178



 Score = 22.2 bits (45), Expect(2) = 1.3
 Identities = 8/13 (61%), Positives = 11/13 (84%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           +T+G EKL NPF+
Sbjct: 180 TTLGYEKLNNPFL 192


>UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 209

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 22/47 (46%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHE 334
           +FTGDTLF G  GR  F  G+ D +  +L   L++LP   KV  GHE
Sbjct: 143 LFTGDTLFRGSMGRTDFPGGSYDDIMDSL-KRLAALPGDYKVCPGHE 188


>UniRef50_Q8REE5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Fusobacterium nucleatum|Rep: Hydroxyacylglutathione
           hydrolase - Fusobacterium nucleatum subsp. nucleatum
          Length = 207

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGRFFEGTAD-QMYKALITILSSLPDHTKVFCGH 337
           D ++ +GDTLF    GR+   T   +M    +  LS LPD T V+ GH
Sbjct: 141 DKILISGDTLFRRSYGRYDLPTGSLEMLCHSLKKLSKLPDETVVYNGH 188


>UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including
           glyoxylases; n=2; Thermoanaerobacter|Rep: Zn-dependent
           hydrolases, including glyoxylases - Thermoanaerobacter
           tengcongensis
          Length = 214

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           V FTGDTLF G  GR  F  G  + +  ++   L +L D T ++ GH
Sbjct: 148 VYFTGDTLFRGSIGRHDFPGGNFETLMASIKERLLTLKDETVIYPGH 194


>UniRef50_Q8NU87 Cluster: Zn-dependent hydrolases, including
           glyoxylases; n=13; Bacteria|Rep: Zn-dependent
           hydrolases, including glyoxylases - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 489

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 21/61 (34%), Positives = 29/61 (47%)
 Frame = -3

Query: 441 GGCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQNLKFAAHVEPTNENVKAKIS 262
           GG    FEG A QM+K+L     +LPDH ++F GH       K    V  T    + + +
Sbjct: 192 GGVDTRFEG-ARQMFKSLKEKFLTLPDHIQIFPGHGSGSACGKALGSVPSTTLGYERQFA 250

Query: 261 W 259
           W
Sbjct: 251 W 251


>UniRef50_Q2W813 Cluster: Zn-dependent hydrolase; n=3;
           Magnetospirillum|Rep: Zn-dependent hydrolase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 224

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           V TGDTLF  G GR     G+  Q++ ++  +L  L D   +F GH
Sbjct: 162 VLTGDTLFRNGVGRTDLPGGSEQQLWASINRLLGLLDDDAMLFSGH 207


>UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-like
           protein; n=3; Leishmania|Rep: Metallo-beta-lactamase
           family protein-like protein - Leishmania major
          Length = 380

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           + ++FTGD LF  G GR     G+ +++ ++L+T L   PD+T +  GH
Sbjct: 294 ERLLFTGDVLFYNGVGRVDLPWGSGERLAESLLT-LEGYPDNTVLLPGH 341


>UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 518

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFEG-TADQMYKALITILSSLPDHTKVFCGHE 334
           VFTGD+LF GGCG  FE  +  Q+ K   T L      T+   G E
Sbjct: 329 VFTGDSLFCGGCGAPFETVSVAQIMKTRATFLEDPRMRTQPGTGQE 374


>UniRef50_Q8Y5A2 Cluster: Lmo2167 protein; n=12; Listeria|Rep:
           Lmo2167 protein - Listeria monocytogenes
          Length = 205

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
 Frame = -3

Query: 477 DSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           D  V  GD LF G  GR   + G  D +  ++ T L  LPD    + GH
Sbjct: 140 DEFVVVGDALFKGSIGRTDLYTGDFDMLINSIKTQLFVLPDDFPAYSGH 188


>UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor;
           n=5; Desulfuromonadales|Rep: Beta-lactamase domain
           protein precursor - Geobacter uraniumreducens Rf4
          Length = 251

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGRF-FEGTA-DQMYKALITILSSLPDHTKVFCGH 337
           ++  V TGDTLF  G GR  F G++ + + + +   L +LP+ T V+ GH
Sbjct: 183 SEGKVITGDTLFADGVGRTDFPGSSHEALIEGIRNKLFTLPEPTLVYPGH 232


>UniRef50_A2DJY1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 248

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLG--GCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           V  GDT+F G  G    + G   Q+  ++I+ + +LPD T ++ GH
Sbjct: 158 VVVGDTVFAGLIGSTNHYGGNKKQLVNSIISKILTLPDDTVIYPGH 203


>UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily; n=1; Clostridium
           acetobutylicum|Rep: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily - Clostridium
           acetobutylicum
          Length = 199

 Score = 29.1 bits (62), Expect(2) = 2.9
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G +CY V       D+ +F+GDTLF    GR  F  G    +  ++ + L  L ++  V+
Sbjct: 128 GGMCYLV-------DNYLFSGDTLFNSSIGRTDFPGGDFSTLINSIKSKLMKLDENIVVY 180

Query: 345 CGH 337
            GH
Sbjct: 181 PGH 183



 Score = 23.4 bits (48), Expect(2) = 2.9
 Identities = 8/13 (61%), Positives = 12/13 (92%)
 Frame = -3

Query: 219 STIGEEKLYNPFM 181
           +TIG EK++NPF+
Sbjct: 187 TTIGYEKIHNPFI 199


>UniRef50_Q5H3M1 Cluster: Beta-lactamase; n=8; Xanthomonadaceae|Rep:
           Beta-lactamase - Xanthomonas oryzae pv. oryzae
          Length = 296

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 4/50 (8%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +F GD+LF+   G     F  G A Q++ A I  L +LPD T+VF  H+Y
Sbjct: 179 LFPGDSLFMPDAGTARCDFPGGDARQLF-ASIQRLYALPDSTRVFVCHDY 227


>UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Beta-lactamase-like
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 288

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 4/57 (7%)
 Frame = -3

Query: 477 DSVVFTGDTLFL--GGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGHEYTLQN 319
           D  VF GDTLF+  GG  R  F  G A  ++ + I  L  LP H K++  H+Y   N
Sbjct: 155 DDNVFVGDTLFMPDGGTARCDFPGGDAGLLWDS-INRLHHLPAHYKIWVCHDYQPDN 210


>UniRef50_A2FNK4 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Trichomonas vaginalis G3|Rep:
           Metallo-beta-lactamase superfamily protein - Trichomonas
           vaginalis G3
          Length = 212

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
 Frame = -3

Query: 474 SVVFTGDTLFLG--GCGRFFEGTADQMYKALITILSSLPDHTKVFCGHEYT 328
           +++FTGDTLF    G   F  G    M ++L  + + +P +  V+ GH  T
Sbjct: 137 NLIFTGDTLFKSARGSTSFIGGNYTDMMQSLYDLFTYIPGNATVYPGHYAT 187


>UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like
           protein - Lentisphaera araneosa HTCC2155
          Length = 213

 Score = 30.7 bits (66), Expect(2) = 3.7
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G  C+ +   E  ++ ++F+GDTLF  G GR     G + ++ K++   L  L   T V 
Sbjct: 136 GSTCFKI---ENSDEQLLFSGDTLFRRGVGRTDLPSGDSREIAKSIKEKLYKLDIDTTVI 192

Query: 345 CGH 337
            GH
Sbjct: 193 PGH 195



 Score = 21.4 bits (43), Expect(2) = 3.7
 Identities = 9/16 (56%), Positives = 13/16 (81%), Gaps = 1/16 (6%)
 Frame = -3

Query: 222 PST-IGEEKLYNPFMR 178
           P+T IGEEK  NP+++
Sbjct: 197 PNTVIGEEKRQNPYIK 212


>UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily
           protein; n=6; Bacteroidetes|Rep: Metallo-beta-lactamase
           superfamily protein - Porphyromonas gingivalis
           (Bacteroides gingivalis)
          Length = 471

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = -3

Query: 504 FVTAPEEGNDSVVFTGDTLFLGGCGR 427
           F+   E G ++ +F+GDTLFLG  GR
Sbjct: 117 FLLIDENGREAALFSGDTLFLGDVGR 142


>UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase
           family; n=6; Proteobacteria|Rep: Zn-dependent
           hydrolases, glyoxylase family - Idiomarina loihiensis
          Length = 292

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           N++ VF GDTLF    G     F  G+A+ +Y++ I  L  L D T+V+  H+Y
Sbjct: 160 NENKVFVGDTLFNPDVGTARCDFPGGSANTLYRS-IQKLFELEDTTEVYICHDY 212


>UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1;
           Bifidobacterium adolescentis L2-32|Rep: Putative
           uncharacterized protein - Bifidobacterium adolescentis
           L2-32
          Length = 264

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRF-FEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           +F GD LF+ GCG    E  A  M+ +L  +   L   T++  GH Y
Sbjct: 148 LFAGDVLFIEGCGLCRDEAAAHAMFGSLERLKRELAPDTRIHPGHTY 194


>UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 214

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = -3

Query: 486 EGNDSVVFTGDTLFLGGCGRF-FEGTADQMYKALITILSSLPDHTKVFCGH 337
           EG+D +V  GDTLF G  GR  F  +   + +  +  L  LP H +V  GH
Sbjct: 143 EGDDIIV--GDTLFAGSVGRTDFPMSDPSLARHSLRRLFELPPHLRVHSGH 191


>UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2;
           Chloroflexus|Rep: Beta-lactamase-like - Chloroflexus
           aggregans DSM 9485
          Length = 395

 Score = 33.1 bits (72), Expect = 4.0
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 427
           GH+ Y V AP    +  + TGD L L GCGR
Sbjct: 247 GHLVYRVIAPN--GERYLLTGDALLLSGCGR 275


>UniRef50_Q9RU26 Cluster: Peptide ABC transporter, permease protein;
           n=2; Deinococcus|Rep: Peptide ABC transporter, permease
           protein - Deinococcus radiodurans
          Length = 376

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -3

Query: 450 LFLGGCGRFFEGTADQMYKALITILSSLPD 361
           L LGG   +F G AD +   L+ +LS++PD
Sbjct: 184 LVLGGIAGYFRGLADTLIMRLVEVLSAIPD 213


>UniRef50_Q81LX4 Cluster: Metallo-beta-lactamase family protein;
           n=14; Bacillus|Rep: Metallo-beta-lactamase family
           protein - Bacillus anthracis
          Length = 208

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
 Frame = -3

Query: 474 SVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVFCGH 337
           S VF+GD LF    GR     G+  ++  ++   L  LPD T V CGH
Sbjct: 144 SAVFSGDVLFQMSIGRTDLPGGSFAELIGSIEEKLFVLPDETAVLCGH 191


>UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein;
           n=4; Desulfuromonadales|Rep: Metallo-beta-lactamase
           family protein - Geobacter sulfurreducens
          Length = 209

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 19/46 (41%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRF-FEGTADQ-MYKALITILSSLPDHTKVFCGH 337
           V TGDTLF    GR  F G++ + +  ++   L +LPD T+V+ GH
Sbjct: 146 VLTGDTLFEESVGRTDFPGSSHEALITSIREKLLTLPDETEVYPGH 191


>UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein;
           n=2; Flexibacteraceae|Rep: Metallo-beta-lactamase family
           protein - Algoriphagus sp. PR1
          Length = 236

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           GH+ ++       +   +  GDTLF G  GR     G  + + + + + L +LPD T VF
Sbjct: 157 GHVVFY-----HSDSKQLIAGDTLFRGSIGRTDLPGGNHELLLQKIKSELFNLPDQTVVF 211

Query: 345 CGH 337
            GH
Sbjct: 212 PGH 214


>UniRef50_Q9FJU6 Cluster: Arabidopsis thaliana genomic DNA,
           chromosome 5, P1 clone:MIK19; n=1; Arabidopsis
           thaliana|Rep: Arabidopsis thaliana genomic DNA,
           chromosome 5, P1 clone:MIK19 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 386

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = -2

Query: 244 KPGKAHSAFYDR*REIIQSIHEGH*VGSSESHWQK 140
           KP +A++    + R+IIQ+ H+    GSSE+ W K
Sbjct: 116 KPSRAYTTGTRKRRKIIQTDHDSELTGSSETRWHK 150


>UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 536

 Score = 32.7 bits (71), Expect = 5.2
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 13/60 (21%)
 Frame = -3

Query: 468 VFTGDTLFLGGCGRFFE-GTADQMYKALITILS----SLPDHTK--------VFCGHEYT 328
           +FTGD +F GGCG  FE  T D++ +      S    + P + K        V+ GHEYT
Sbjct: 358 LFTGDCIFCGGCGAMFEVTTVDEVIQTRDLFFSHRMRTHPTNNKMFSADDVLVYVGHEYT 417


>UniRef50_Q484V0 Cluster: Metallo-beta-lactamase family protein;
           n=1; Colwellia psychrerythraea 34H|Rep:
           Metallo-beta-lactamase family protein - Colwellia
           psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 299

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 16/46 (34%), Positives = 24/46 (52%)
 Frame = -3

Query: 474 SVVFTGDTLFLGGCGRFFEGTADQMYKALITILSSLPDHTKVFCGH 337
           SV+F GD +F    G   +G + Q  K L  +L+ + D   +F GH
Sbjct: 176 SVIFVGDVVFNNMHGFMNDGNSAQWLKVLQKLLTEIADVKLLFTGH 221


>UniRef50_Q47LT8 Cluster: Putative hydrolase; n=1; Thermobifida
           fusca YX|Rep: Putative hydrolase - Thermobifida fusca
           (strain YX)
          Length = 209

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLF-LGGCGRFFEGTADQMYKALITILSSLPDHTKVFC 343
           G +C +V A      + VFTGDTL   G  G +     + +  ++   L +LP  T V+ 
Sbjct: 139 GSVCLYVPAL-----ATVFTGDTLLGHGASGEYAPDDPETLRTSVAGRLFTLPPETTVYS 193

Query: 342 GHEYTLQNLKFAAHVE 295
           GH        +AA  E
Sbjct: 194 GHGAAAPISAWAAQAE 209


>UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 471

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 7/66 (10%)
 Frame = -3

Query: 513 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR-------FFEGTADQMYKALITILSSLPDHT 355
           +  F  +  E +   +FTGD LF+G  GR         +  A Q+Y ++   L  +PD+T
Sbjct: 125 VLLFDQSRSETSPWCMFTGDFLFVGDVGRPDLLGEEEKQKLARQLYDSVFNQLEGVPDYT 184

Query: 354 KVFCGH 337
           +++  H
Sbjct: 185 EIYPAH 190


>UniRef50_A0Z233 Cluster: Putative uncharacterized protein; n=3;
           Proteobacteria|Rep: Putative uncharacterized protein -
           marine gamma proteobacterium HTCC2080
          Length = 308

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
 Frame = -3

Query: 480 NDSVVFTGDTLFLGGCGR----FFEGTADQMYKALITILSSLPDHTKVFCGHEY 331
           ND++ F GDTLF+   G     F  G A  +++++  +L+ LP  T++F  H+Y
Sbjct: 153 NDAL-FVGDTLFMPDAGTARCDFPGGNAHALFQSIQRLLT-LPGDTRIFVCHDY 204


>UniRef50_Q59K47 Cluster: Putative uncharacterized protein; n=2;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 307

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 16/55 (29%), Positives = 25/55 (45%)
 Frame = -3

Query: 348 FCGHEYTLQNLKFAAHVEPTNENVKAKISWSQDRRNQGKPTVPSTIGEEKLYNPF 184
           +CGH Y  Q L   + ++P N+N     S +    N  +PT  S   +   YN +
Sbjct: 140 YCGH-YMKQGLSMNSQIDPKNDNYPQPTSNNYSNNNYPQPTNYSNYPQPTSYNNY 193


>UniRef50_Q2U6W1 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 432

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +2

Query: 161 TANSVTLMNGLYNFSSPIVEGTVGFPWFRLSCDQL 265
           TA+S+ LM+ L   + P++ G+     F L C QL
Sbjct: 101 TASSINLMSSLEKLAKPVIHGSENVAHFGLQCQQL 135


>UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3;
           Methanosarcina|Rep: Metallo-beta-lactamase -
           Methanosarcina acetivorans
          Length = 457

 Score = 32.3 bits (70), Expect = 6.9
 Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
 Frame = -3

Query: 507 YFVTAPEEGNDSV-VFTGDTLFLGGCGR 427
           Y +T P+ G + + VFTGD LF+G  GR
Sbjct: 117 YVLTDPDAGKEPIMVFTGDALFVGDVGR 144


>UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 210

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -3

Query: 519 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR--FFEGTADQMYKALITILSSLPDHTKVF 346
           G +C++     E + S + +GDTLF G  G   F     D M+ +L   L+ LP  T V+
Sbjct: 134 GSVCFY-----EISQSKLLSGDTLFKGSIGNISFPTSQPDLMWTSL-DKLAQLPPSTSVY 187

Query: 345 CGH 337
            GH
Sbjct: 188 PGH 190


>UniRef50_A3EQ47 Cluster: Zn-dependent hydrolase; n=1;
           Leptospirillum sp. Group II UBA|Rep: Zn-dependent
           hydrolase - Leptospirillum sp. Group II UBA
          Length = 293

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
 Frame = -3

Query: 471 VVFTGDTLFLGGCGRFFEGTADQMYKALITI---LSSLPDHTKVFCGH 337
           V+F GD +F G CG+    T D    +L T+   L+SLP  T +  GH
Sbjct: 221 VLFVGDGIFCGSCGK--PRTPDHFSDSLGTVARLLNSLPAETILVSGH 266


>UniRef50_A0ZDI7 Cluster: TPR repeat protein; n=1; Nodularia
           spumigena CCY 9414|Rep: TPR repeat protein - Nodularia
           spumigena CCY 9414
          Length = 743

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
 Frame = -3

Query: 288 NENVKAKISWSQDRRNQGKPTVPSTIGEE---KLYNPFMRVTELAVQNHTG 145
           +EN++ +ISW   +  QGK T P   GE+   ++ N + ++ E+ V  H+G
Sbjct: 696 DENLRQQISW---KLRQGKKTAPLWNGEQFTREMENAYRQMWEIYVNEHSG 743


>UniRef50_Q55BX0 Cluster: Putative uncharacterized protein; n=3;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 370

 Score = 31.9 bits (69), Expect = 9.2
 Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
 Frame = +3

Query: 312 ILNSAKCTHGHKTL*--CGQAGCSELLLMLCTFDLPCLQRTCH 434
           ILN   CT+G+K +   C + GCS  + ++C    PC   TC+
Sbjct: 252 ILNDTICTNGNKCVNSTCTEDGCSLPVPIVCEDGNPCSDDTCN 294


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 518,110,209
Number of Sequences: 1657284
Number of extensions: 9956914
Number of successful extensions: 21767
Number of sequences better than 10.0: 239
Number of HSP's better than 10.0 without gapping: 21049
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21589
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 32619212418
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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