Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= msgV0965.Seq
(449 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 78 1e-13
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 77 1e-13
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 76 4e-13
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 76 4e-13
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 75 1e-12
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 74 1e-12
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 73 2e-12
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 73 2e-12
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 72 7e-12
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 71 9e-12
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 70 3e-11
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 67 1e-10
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 64 2e-09
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 63 2e-09
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 62 7e-09
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 60 2e-08
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 57 2e-07
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 57 2e-07
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 54 1e-06
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 54 1e-06
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 54 2e-06
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 53 3e-06
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 52 4e-06
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 52 6e-06
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 51 1e-05
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 50 3e-05
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 48 7e-05
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 48 7e-05
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 48 9e-05
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 47 2e-04
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 47 2e-04
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 46 3e-04
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 46 3e-04
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 46 3e-04
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 46 4e-04
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 46 5e-04
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 45 7e-04
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 45 7e-04
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 45 7e-04
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 45 7e-04
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 45 9e-04
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 44 0.001
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 44 0.001
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 44 0.001
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 44 0.002
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 43 0.004
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 43 0.004
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 43 0.004
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 42 0.006
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 42 0.008
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 42 0.008
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 41 0.011
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 41 0.014
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 41 0.014
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 41 0.014
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 40 0.019
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 40 0.025
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 40 0.025
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 40 0.025
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 40 0.033
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 40 0.033
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 39 0.044
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 39 0.044
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 39 0.044
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 39 0.058
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 39 0.058
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 39 0.058
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 38 0.076
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 38 0.10
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 38 0.10
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 38 0.13
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 37 0.18
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 37 0.18
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 37 0.23
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 37 0.23
UniRef50_Q21HW6 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.31
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 36 0.31
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 36 0.31
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 36 0.41
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 35 0.71
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 35 0.71
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 35 0.94
UniRef50_A3AIZ4 Cluster: Putative uncharacterized protein; n=3; ... 34 1.2
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 33 2.9
UniRef50_Q1MXW3 Cluster: TonB-dependent receptor; n=1; Oceanobac... 33 2.9
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 33 2.9
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 33 2.9
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 33 3.8
UniRef50_Q5QU95 Cluster: Uncharacterized conserved secreted prot... 33 3.8
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 33 3.8
UniRef50_A4I4B9 Cluster: Flagellar radial spoke protein-like, pu... 33 3.8
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 33 3.8
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 3.8
UniRef50_A2QKB8 Cluster: Contig An04c0370, complete genome; n=1;... 32 5.0
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 32 5.0
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 32 6.6
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 32 6.6
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 32 6.6
UniRef50_Q47706 Cluster: Membrane-associated protein uidC precur... 32 6.6
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 32 6.6
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 31 8.8
UniRef50_UPI00015A6833 Cluster: hypothetical protein LOC572435; ... 31 8.8
UniRef50_Q0RVX2 Cluster: Putative uncharacterized protein; n=1; ... 31 8.8
UniRef50_Q41068 Cluster: P.sativum vicilin; n=1; Pisum sativum|R... 31 8.8
UniRef50_Q4N5S4 Cluster: Putative uncharacterized protein; n=1; ... 31 8.8
UniRef50_A2QN02 Cluster: Putative uncharacterized protein precur... 31 8.8
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 31 8.8
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 77.8 bits (183), Expect = 1e-13
Identities = 38/66 (57%), Positives = 50/66 (75%), Gaps = 1/66 (1%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRS-YQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 431
+SH+NT + V G S + A+K +++ +IPAGVPRKPGMTRDDLFNTNASIVRD+A
Sbjct: 67 ISHINTNSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAK 126
Query: 432 SIAQNA 449
+ A+ A
Sbjct: 127 AAAEAA 132
Score = 53.6 bits (123), Expect = 2e-06
Identities = 29/54 (53%), Positives = 36/54 (66%)
Frame = +1
Query: 94 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAAD
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAAD 66
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 77.4 bits (182), Expect = 1e-13
Identities = 36/65 (55%), Positives = 43/65 (66%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
L H NTPAKV+G + DV VIPAGVPRKPGMTRDDLF NA IVR++ +
Sbjct: 121 LGHCNTPAKVAGFTGKEELAGCLAGVDVVVIPAGVPRKPGMTRDDLFGINAGIVRELVEA 180
Query: 435 IAQNA 449
+A +A
Sbjct: 181 VADHA 185
Score = 41.9 bits (94), Expect = 0.006
Identities = 22/33 (66%), Positives = 26/33 (78%)
Frame = +1
Query: 157 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
IGQPL+LL+K +PLV+ L LYDIA V GV AD
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANV-DGVTAD 120
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 75.8 bits (178), Expect = 4e-13
Identities = 36/64 (56%), Positives = 46/64 (71%), Gaps = 1/64 (1%)
Frame = +3
Query: 255 LSHMNTPAKVSG-TRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 431
+ H+NT + V G D + + A+ ADV +IPAGVPRKPGMTRDDLF TNASIVRD+A
Sbjct: 72 IGHINTTSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAF 131
Query: 432 SIAQ 443
+ +
Sbjct: 132 AAGE 135
Score = 53.2 bits (122), Expect = 3e-06
Identities = 29/54 (53%), Positives = 35/54 (64%)
Frame = +1
Query: 94 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAAD
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRG-APGVAAD 71
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 75.8 bits (178), Expect = 4e-13
Identities = 35/64 (54%), Positives = 45/64 (70%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH NTP++V +KD +V VIPAGVPRKPGMTRDDLFN NA+IV+ + +
Sbjct: 126 LSHCNTPSQVRDFTGPSELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTLVEA 185
Query: 435 IAQN 446
+A+N
Sbjct: 186 VAEN 189
Score = 44.0 bits (99), Expect = 0.002
Identities = 23/33 (69%), Positives = 27/33 (81%)
Frame = +1
Query: 157 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
IGQPL+LL+K +PLV+ L LYDIA V GVAAD
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANV-KGVAAD 125
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 74.5 bits (175), Expect = 1e-12
Identities = 35/64 (54%), Positives = 49/64 (76%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH++T AKV+ + +AA++ V IPAGVPRKPGMTRDDLFNTNASIV++++ +
Sbjct: 12 LSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVKNLSEA 71
Query: 435 IAQN 446
A++
Sbjct: 72 CAKH 75
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 74.1 bits (174), Expect = 1e-12
Identities = 39/68 (57%), Positives = 50/68 (73%), Gaps = 5/68 (7%)
Frame = +3
Query: 255 LSHMNTPAKVSGTR-----DLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVR 419
LSH+ +PAKV+G + D + Q A+ ++D+ VIPAGVPRKPGMTR DLFN NASI+R
Sbjct: 45 LSHICSPAKVTGYQPSSKEDRDTIQKALVNSDLVVIPAGVPRKPGMTRADLFNINASIIR 104
Query: 420 DIALSIAQ 443
DI SI +
Sbjct: 105 DIVGSIGK 112
Score = 40.3 bits (90), Expect = 0.019
Identities = 20/33 (60%), Positives = 25/33 (75%)
Frame = +1
Query: 157 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
IGQPL+LLLK NP V+ L+L+D+ GVAAD
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAAD 44
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 73.3 bits (172), Expect = 2e-12
Identities = 36/64 (56%), Positives = 42/64 (65%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH+ T A V G +K DV VIPAGVPRKPGMTRDDLFNTNA+IV + +
Sbjct: 68 LSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAA 127
Query: 435 IAQN 446
AQ+
Sbjct: 128 CAQH 131
Score = 65.3 bits (152), Expect = 6e-10
Identities = 37/71 (52%), Positives = 47/71 (66%)
Frame = +1
Query: 43 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 222
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 223 IAPVTPGVAAD 255
IA TPGVAAD
Sbjct: 58 IAH-TPGVAAD 67
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 73.3 bits (172), Expect = 2e-12
Identities = 36/64 (56%), Positives = 42/64 (65%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH+ T A V G +K DV VIPAGVPRKPGMTRDDLFNTNA+IV + +
Sbjct: 68 LSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAA 127
Query: 435 IAQN 446
AQ+
Sbjct: 128 CAQH 131
Score = 64.1 bits (149), Expect = 1e-09
Identities = 36/71 (50%), Positives = 47/71 (66%)
Frame = +1
Query: 43 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 222
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 223 IAPVTPGVAAD 255
IA TPGVAAD
Sbjct: 58 IAH-TPGVAAD 67
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 71.7 bits (168), Expect = 7e-12
Identities = 35/63 (55%), Positives = 42/63 (66%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
+SHMNT A V G + A+ D+ +IPAGVPRKPGMTRDDLFN NA IVR +
Sbjct: 88 ISHMNTGAVVRGFLGQPQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEG 147
Query: 435 IAQ 443
IA+
Sbjct: 148 IAK 150
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/44 (56%), Positives = 28/44 (63%)
Frame = +1
Query: 124 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
FK IGQPLALL+K NPLV+ L LYD+ TPGV AD
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTAD 87
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 71.3 bits (167), Expect = 9e-12
Identities = 33/63 (52%), Positives = 42/63 (66%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH++TP VS + + +A + VIPAGVPRKPGMTRDDLFN NA I+ + S
Sbjct: 70 LSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDS 129
Query: 435 IAQ 443
IA+
Sbjct: 130 IAE 132
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/67 (53%), Positives = 44/67 (65%), Gaps = 5/67 (7%)
Frame = +3
Query: 255 LSHMNTPAKVS-----GTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVR 419
LSH+NTP +VS D + + A+ A V VIPAGVPRKPGMTRDDL N NA I++
Sbjct: 77 LSHVNTPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIK 136
Query: 420 DIALSIA 440
+A IA
Sbjct: 137 TLAKGIA 143
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 67.3 bits (157), Expect = 1e-10
Identities = 33/58 (56%), Positives = 44/58 (75%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIA 428
LSH+NT K+S +LR ++ D+++ +IPAGVPRKPGMTRDDLFN NA I++ IA
Sbjct: 91 LSHVNTNMKLSLHDNLRD---SLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIA 145
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 63.7 bits (148), Expect = 2e-09
Identities = 31/65 (47%), Positives = 43/65 (66%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH+NT + G D S + + +A V +IPAGVPRKPG+TRDDLF NA IV+ + +
Sbjct: 45 LSHINTNSSCVGY-DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTA 103
Query: 435 IAQNA 449
+ + A
Sbjct: 104 VGKFA 108
Score = 37.5 bits (83), Expect = 0.13
Identities = 18/33 (54%), Positives = 23/33 (69%)
Frame = +1
Query: 157 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
+GQPL+LLLK +P V+ LALYDI G+ D
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKD 44
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 63.3 bits (147), Expect = 2e-09
Identities = 34/66 (51%), Positives = 46/66 (69%), Gaps = 2/66 (3%)
Frame = +3
Query: 255 LSHMNTPAKVSG--TRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIA 428
LSH+NT A G T D+ A+K A V VIPAGVPR+PG+TRDDLF NA IV+++
Sbjct: 45 LSHINTNADCVGYSTDDIGQ---ALKGAAVVVIPAGVPRRPGITRDDLFKLNAGIVKNLV 101
Query: 429 LSIAQN 446
++A++
Sbjct: 102 SNVAKH 107
Score = 39.9 bits (89), Expect = 0.025
Identities = 19/33 (57%), Positives = 25/33 (75%)
Frame = +1
Query: 157 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
+GQPL+LLLK N +++ LALYDI + GVA D
Sbjct: 13 VGQPLSLLLKLNTMISELALYDI-KLAEGVATD 44
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 61.7 bits (143), Expect = 7e-09
Identities = 28/63 (44%), Positives = 41/63 (65%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH+NT A V + A+ AD+ VIPAG+PRKPGM R+DL + NAS+ ++A +
Sbjct: 71 LSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFA 130
Query: 435 IAQ 443
++
Sbjct: 131 ASE 133
Score = 41.1 bits (92), Expect = 0.011
Identities = 22/46 (47%), Positives = 26/46 (56%)
Frame = +1
Query: 118 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
R K IGQPL+LLLK NP ++ L+LYDI T GV D
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVD 70
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 60.5 bits (140), Expect = 2e-08
Identities = 25/65 (38%), Positives = 43/65 (66%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH+NT + G ++ ++ +++ ++ AG+PRKPGMTRDDLF NA I++++ +
Sbjct: 46 LSHINTNSDSEGYNKDEDFKNLLEGSELVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVK 105
Query: 435 IAQNA 449
A+ A
Sbjct: 106 YAKFA 110
Score = 49.2 bits (112), Expect = 4e-05
Identities = 23/33 (69%), Positives = 27/33 (81%)
Frame = +1
Query: 157 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
IGQPL+LLLK NP V+ LALYDI+ +T GVA D
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVAKD 45
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/65 (43%), Positives = 42/65 (64%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH KV+G + A+ AD+ ++ AG+PR+PGMT DDLFNTNA V +++ +
Sbjct: 52 LSHFPRKVKVTGY-PTKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAA 110
Query: 435 IAQNA 449
+A+ A
Sbjct: 111 VARYA 115
Score = 38.3 bits (85), Expect = 0.076
Identities = 25/45 (55%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Frame = +1
Query: 124 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAAD 255
FK IGQPLAL L QN V+ LALYDI V P GVA D
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVD 51
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 56.8 bits (131), Expect = 2e-07
Identities = 29/57 (50%), Positives = 37/57 (64%)
Frame = +3
Query: 279 KVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
K+ RD + A K DV V+ AGVPRKPGMTRDDLF NA I+ D+ L+ A ++
Sbjct: 62 KIGHKRDPALAELA-KGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSS 117
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 54.4 bits (125), Expect = 1e-06
Identities = 26/43 (60%), Positives = 32/43 (74%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
I DA + +I AGVPRKPGM+R DL TNA IVR +A +IA+ A
Sbjct: 85 IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYA 127
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQA---AIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
LSH++TP + S + +A V +IPAGVPRKPGM+RDDL NA I++ +
Sbjct: 101 LSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSL 160
Query: 426 ALSIAQ 443
IA+
Sbjct: 161 GEDIAK 166
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/58 (48%), Positives = 37/58 (63%)
Frame = +3
Query: 276 AKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
AK+ GT+ SY A I ADV ++ AGVPRKPGM+RDDL N +++ + I NA
Sbjct: 58 AKLKGTQ---SY-ADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNA 111
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/43 (53%), Positives = 31/43 (72%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
+ +KDADV ++ AGVPRKPGM+RDDL NA I+ + +I Q
Sbjct: 221 SVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQ 263
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 52.4 bits (120), Expect = 4e-06
Identities = 26/58 (44%), Positives = 35/58 (60%)
Frame = +3
Query: 276 AKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
AK +G D AAI+ ADV ++ AGVPRKPGM+RDDL N ++ + I + A
Sbjct: 58 AKFTGANDY----AAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYA 111
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 52.0 bits (119), Expect = 6e-06
Identities = 24/62 (38%), Positives = 37/62 (59%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH++ KV G + ++A+ ADV V+ AG+PR PGM RD L N ++ +A +
Sbjct: 66 LSHISQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATA 125
Query: 435 IA 440
I+
Sbjct: 126 IS 127
Score = 34.3 bits (75), Expect = 1.2
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = +1
Query: 118 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
R K IGQPL+LLL++ P + LAL+D++ + G+A D
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEM-KGIATD 65
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 50.8 bits (116), Expect = 1e-05
Identities = 22/43 (51%), Positives = 32/43 (74%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
+K +++ V+ AG+ RKPGMTR DL + NA I++DIA I +NA
Sbjct: 67 LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENA 109
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 49.6 bits (113), Expect = 3e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
IKDAD+ VI AGV RK GMTR+DL N I++ +A S+
Sbjct: 67 IKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESV 105
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 48.4 bits (110), Expect = 7e-05
Identities = 25/57 (43%), Positives = 38/57 (66%)
Frame = +3
Query: 279 KVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
+V+GT D YQ + D+DV VI AG+ RKPGM+R++L + NA IV + + Q++
Sbjct: 59 RVTGTSD---YQDTL-DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHS 111
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 48.4 bits (110), Expect = 7e-05
Identities = 21/52 (40%), Positives = 32/52 (61%)
Frame = +3
Query: 288 GTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
G + + + + + + +IPAG+PRKPG TRDDLF NA I + I + A+
Sbjct: 145 GQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAK 196
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 48.0 bits (109), Expect = 9e-05
Identities = 20/38 (52%), Positives = 28/38 (73%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIA 428
A ++DV VI +G+PRKPGMTR++L NA IV+ +A
Sbjct: 67 AQTANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVA 104
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 47.2 bits (107), Expect = 2e-04
Identities = 22/40 (55%), Positives = 28/40 (70%)
Frame = +3
Query: 327 DADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
DADV VI AG+PRKPG TR DL N N +I++ I I ++
Sbjct: 74 DADVVVITAGIPRKPGETRLDLVNKNTTILKSIIKPIVKS 113
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 47.2 bits (107), Expect = 2e-04
Identities = 21/49 (42%), Positives = 35/49 (71%)
Frame = +3
Query: 291 TRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
T D +Y+ ++ +DV V+ AG+ RKPGM+R+DLF+ N I+ D++ +I
Sbjct: 65 TSDSSNYKN-MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNI 112
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 46.4 bits (105), Expect = 3e-04
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIA 428
I AD+ VI AG PRKPGM+R DLF NA I+ D+A
Sbjct: 68 ISGADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLA 103
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 46.4 bits (105), Expect = 3e-04
Identities = 20/43 (46%), Positives = 29/43 (67%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
I+ +D+ ++ AG+PRKPGMTR+ L NA IV +I I + A
Sbjct: 66 IEGSDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYA 108
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/82 (35%), Positives = 50/82 (60%)
Frame = +3
Query: 204 QAGFIRHSACDPRRRSRLSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTR 383
Q G + +A D ++ + L + A+V+G+ + Y+ I D+D+ VI AG PRKPGM+R
Sbjct: 37 QEGVAQGAALDIQQSAPLFDFD--ARVTGSTN---YEL-IADSDLVVITAGKPRKPGMSR 90
Query: 384 DDLFNTNASIVRDIALSIAQNA 449
D+ ++N I+ DI ++ + A
Sbjct: 91 SDVLDSNLPIITDIMNNVMRFA 112
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 46.0 bits (104), Expect = 4e-04
Identities = 22/48 (45%), Positives = 35/48 (72%)
Frame = +3
Query: 306 SYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
SY+ I +++V +I AG PR P MTR+DL NASI+++I+ ++A+ A
Sbjct: 66 SYEE-IAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIA 112
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 45.6 bits (103), Expect = 5e-04
Identities = 20/29 (68%), Positives = 23/29 (79%)
Frame = +3
Query: 360 PRKPGMTRDDLFNTNASIVRDIALSIAQN 446
PRKPGMTRDDLFNTNAS+V + AQ+
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQH 89
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 45.2 bits (102), Expect = 7e-04
Identities = 20/39 (51%), Positives = 27/39 (69%)
Frame = +3
Query: 327 DADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
DADV V+ AG+PRKPG TR DL NA+I++ +A+
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAE 111
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/42 (50%), Positives = 29/42 (69%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
+KDAD VI AG P+KPG TR +L N I+R+IAL + ++
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKES 110
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/37 (56%), Positives = 25/37 (67%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
A +DAD+ VI AGVPRKPG +R DL N N I+ I
Sbjct: 68 ADARDADIVVITAGVPRKPGESRLDLINRNTKILESI 104
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 45.2 bits (102), Expect = 7e-04
Identities = 27/61 (44%), Positives = 32/61 (52%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LSH P S T+ A KDAD+ VI AG+P+KPG TR DL N I + I
Sbjct: 50 LSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRG 108
Query: 435 I 437
I
Sbjct: 109 I 109
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 44.8 bits (101), Expect = 9e-04
Identities = 19/45 (42%), Positives = 32/45 (71%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
A +K +DV ++ AGVP+KPG TR L NA ++++IA ++++ A
Sbjct: 63 ADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYA 107
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 44.4 bits (100), Expect = 0.001
Identities = 21/45 (46%), Positives = 30/45 (66%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
A I+ +D+ V+ AG PRK G TR+DL NA +V+ A +IA+ A
Sbjct: 65 ALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFA 109
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 44.4 bits (100), Expect = 0.001
Identities = 20/46 (43%), Positives = 25/46 (54%)
Frame = +3
Query: 279 KVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIV 416
K+ G A + DV +I AGVPRKPGM R DL N N ++
Sbjct: 71 KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVM 116
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 44.4 bits (100), Expect = 0.001
Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Frame = +3
Query: 246 RSRLSHMNTPAKVSG---TRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIV 416
+ L+ M+ A+V G T + Y+ ++ +D+ VI AG PR+PGM+R+DL N I+
Sbjct: 56 KQMLAAMDIDARVEGYTVTPEGEGYEP-LEGSDIVVITAGFPRRPGMSREDLLEANIRII 114
Query: 417 RDIALSIAQNA 449
IA I + A
Sbjct: 115 SVIADRIKRYA 125
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/38 (52%), Positives = 26/38 (68%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
KDAD+ VI AGVPR PG TR D+ + + VRDI ++
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNL 108
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 43.6 bits (98), Expect = 0.002
Identities = 20/39 (51%), Positives = 27/39 (69%)
Frame = +3
Query: 330 ADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
+DV VI AG+PR+PG TR DL NA I+ DI S+ ++
Sbjct: 72 SDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEH 110
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
++ +DV +I AG PR PGM+RDDL NA IV+ + I + A
Sbjct: 71 MEGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYA 113
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 42.7 bits (96), Expect = 0.004
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
LS +V G+ + +K +++ V+ AG RKPGMTR DL NASIV+ + +
Sbjct: 48 LSEQGIDVEVKGSNNFED----MKGSNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVEN 103
Query: 435 IAQNA 449
+ + A
Sbjct: 104 VKKYA 108
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 42.7 bits (96), Expect = 0.004
Identities = 22/65 (33%), Positives = 34/65 (52%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
L+ +V G+ D + + D+ V+ AG RKPGMTR DL NA IV+ +
Sbjct: 48 LAEQGIDTEVRGSNDYSDMEGS----DIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEK 103
Query: 435 IAQNA 449
+ ++A
Sbjct: 104 VKEHA 108
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 41.9 bits (94), Expect = 0.006
Identities = 17/35 (48%), Positives = 24/35 (68%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
++ DV V AG PR+PGM+RDDL NA ++R +
Sbjct: 65 LRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTV 99
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 41.5 bits (93), Expect = 0.008
Identities = 19/35 (54%), Positives = 24/35 (68%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
+++AD VI AG PRK M+R DL NA I+RDI
Sbjct: 72 VENADAIVITAGKPRKADMSRRDLAKVNAQIIRDI 106
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 41.5 bits (93), Expect = 0.008
Identities = 23/60 (38%), Positives = 32/60 (53%)
Frame = +3
Query: 270 TPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
TPA V G D+ D+DV I AG +KPG TR DL NA+I+R + + + +
Sbjct: 62 TPASVMGGADVHD----TADSDVVFITAGARQKPGQTRLDLAGVNANILRSLMPQLVEQS 117
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/49 (42%), Positives = 30/49 (61%)
Frame = +3
Query: 279 KVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
+++GT D A +DV V+ AG R+PGM+RDDL TN IV ++
Sbjct: 64 RITGTNDY----AQTAGSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEV 108
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 40.7 bits (91), Expect = 0.014
Identities = 18/43 (41%), Positives = 29/43 (67%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
I+ + V V+ AG RKPGM+R+DL + N I+ ++A I ++A
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHA 114
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 40.7 bits (91), Expect = 0.014
Identities = 23/57 (40%), Positives = 33/57 (57%)
Frame = +3
Query: 279 KVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
++SG+ DL A+ A+ VI AG PR+PGM+R DL NA I+ + I +A
Sbjct: 180 RLSGSDDL----VALAGAEYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHA 232
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 40.7 bits (91), Expect = 0.014
Identities = 20/42 (47%), Positives = 29/42 (69%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
+KD DV VI AG P+KPG TR ++ NA I+ +IA +I ++
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKS 112
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 40.3 bits (90), Expect = 0.019
Identities = 18/39 (46%), Positives = 24/39 (61%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
+KD DV V+ AG RKPG TR DL N I +++ +I
Sbjct: 72 VKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNI 110
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 39.9 bits (89), Expect = 0.025
Identities = 17/43 (39%), Positives = 28/43 (65%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
+K +D+ VI AG+PR+ GM+R+DL N I++ +I + A
Sbjct: 86 LKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYA 128
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 39.9 bits (89), Expect = 0.025
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = +3
Query: 327 DADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
DAD+ VI AG P+KPG TR DL N +I + I + ++
Sbjct: 76 DADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVES 115
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 39.9 bits (89), Expect = 0.025
Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +3
Query: 234 DPRRRSRLSHMNTPAKVS-GTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNAS 410
+ R ++ + A VS GTR + + DA V ++ AG +KPG +R DL NA
Sbjct: 35 EDRAQAEAEDIAHAAPVSHGTRVWHGGHSELADAQVVILTAGANQKPGESRLDLLEKNAD 94
Query: 411 IVRDIALSIAQNA 449
I R++ I + A
Sbjct: 95 IFRELVPQITRAA 107
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 39.5 bits (88), Expect = 0.033
Identities = 20/39 (51%), Positives = 23/39 (58%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
+ DAD+ VI AG K G TRDDL N+ I DIA I
Sbjct: 68 LTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKI 106
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 39.5 bits (88), Expect = 0.033
Identities = 19/54 (35%), Positives = 33/54 (61%)
Frame = +3
Query: 285 SGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
+G++ A K AD+ ++ AG P+K G TR ++ N+ I++DIAL I ++
Sbjct: 56 TGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMKDIALEIKKS 109
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 39.1 bits (87), Expect = 0.044
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +3
Query: 327 DADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
D+D+ V+ AG ++ G TR DL NASI+ IA IA++
Sbjct: 72 DSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAES 111
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 39.1 bits (87), Expect = 0.044
Identities = 19/38 (50%), Positives = 27/38 (71%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
KDAD+ VI AG P++PG TR +L N+ I++ IA +I
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAI 109
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 39.1 bits (87), Expect = 0.044
Identities = 18/41 (43%), Positives = 28/41 (68%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
+DAD+ VI AG +KPG +R DL + NA I++ I +I ++
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKS 112
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 38.7 bits (86), Expect = 0.058
Identities = 17/32 (53%), Positives = 19/32 (59%)
Frame = +3
Query: 318 AIKDADVXVIPAGVPRKPGMTRDDLFNTNASI 413
A KDADV + +PRKPGM R DL N I
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREI 110
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 38.7 bits (86), Expect = 0.058
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
A KD+D+ +I AGV KPG TR D+ N N I + I + +
Sbjct: 69 ADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVK 111
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 38.7 bits (86), Expect = 0.058
Identities = 17/40 (42%), Positives = 27/40 (67%)
Frame = +3
Query: 327 DADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQN 446
+AD+ VI AG+ +KPG TR DL + N+ I +DI ++ +
Sbjct: 73 NADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSS 112
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 38.3 bits (85), Expect = 0.076
Identities = 15/32 (46%), Positives = 23/32 (71%)
Frame = +3
Query: 330 ADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
+++ VI AG+ RKPGMTR++L N I+ D+
Sbjct: 70 SEIVVITAGIARKPGMTREELLAINQKIMTDV 101
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 37.9 bits (84), Expect = 0.10
Identities = 18/38 (47%), Positives = 25/38 (65%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
K AD+ VI AG+ +KPG TR L NA I+++I +I
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNI 107
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 37.9 bits (84), Expect = 0.10
Identities = 18/32 (56%), Positives = 21/32 (65%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIV 416
+KD D+ VI AG RK G +RDDL NA IV
Sbjct: 67 LKDFDIVVITAGFARKDGQSRDDLAMMNAKIV 98
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 37.5 bits (83), Expect = 0.13
Identities = 18/40 (45%), Positives = 21/40 (52%)
Frame = +3
Query: 318 AIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
A+ DA V G PRK GMTR+DL NA I + I
Sbjct: 71 ALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDI 110
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 37.1 bits (82), Expect = 0.18
Identities = 18/34 (52%), Positives = 21/34 (61%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
KDAD+ VI AG P KPG +R D +A IV I
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTI 107
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 37.1 bits (82), Expect = 0.18
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
KD+D+ +I AG KPG TR DL N N I + I + +
Sbjct: 71 KDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVK 110
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 36.7 bits (81), Expect = 0.23
Identities = 16/32 (50%), Positives = 19/32 (59%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVR 419
+D DV V G PRKPGM R DL N +I +
Sbjct: 119 QDVDVAVFIGGFPRKPGMERKDLLTINGNIFK 150
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 36.7 bits (81), Expect = 0.23
Identities = 18/40 (45%), Positives = 23/40 (57%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
KDA VI AG +KPG TR DL N SI ++I + +
Sbjct: 86 KDATAVVITAGKNQKPGETRMDLLKANISIFKEILREVTK 125
>UniRef50_Q21HW6 Cluster: AMP-dependent synthetase and ligase; n=1;
Saccharophagus degradans 2-40|Rep: AMP-dependent
synthetase and ligase - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 588
Score = 36.3 bits (80), Expect = 0.31
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Frame = +3
Query: 162 PAFGPSTEAESSGDQAGFIRHSACDPRRRSRLSHMNTPAKVSGTRDLRSYQAAIKDADVX 341
PA PS A S D G R RRS L H++ P + R S Q +K D+
Sbjct: 480 PALSPSAGAAFSLDVDGDERLIVVQSVRRSHLKHIDAPEIFNAIRRSVSAQYGVKVHDIQ 539
Query: 342 VI-PAGVPR 365
++ PA +PR
Sbjct: 540 LLMPASIPR 548
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 36.3 bits (80), Expect = 0.31
Identities = 20/38 (52%), Positives = 22/38 (57%)
Frame = +3
Query: 336 VXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
+ VI AGVPR M RDDL N IV D A IA+ A
Sbjct: 75 IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFA 112
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 36.3 bits (80), Expect = 0.31
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +3
Query: 330 ADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
A + V+ AG + PG +R DL NA I RDI ++ Q A
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYA 108
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 35.9 bits (79), Expect = 0.41
Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 3/53 (5%)
Frame = +3
Query: 288 GTRDLRSYQAAIKD---ADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
GT ++ ++KD +D+ VI AG PR PG R DL NA I+ +A +I
Sbjct: 57 GTNIRVTWTTSLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTI 109
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 35.1 bits (77), Expect = 0.71
Identities = 19/63 (30%), Positives = 35/63 (55%)
Frame = +3
Query: 255 LSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 434
L+ ++T K+ +S + AI A V + G KPG ++ +LF+ N VR++A+
Sbjct: 73 LNEIDTRTKLKSF-SCKSLKNAIVGAHVVISTGGCQEKPGSSQRELFDKNLDNVRNVAMF 131
Query: 435 IAQ 443
+A+
Sbjct: 132 LAE 134
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 35.1 bits (77), Expect = 0.71
Identities = 16/32 (50%), Positives = 18/32 (56%)
Frame = +3
Query: 318 AIKDADVXVIPAGVPRKPGMTRDDLFNTNASI 413
A KDADV ++ PR PGM R DL N I
Sbjct: 79 AFKDADVALLVGARPRGPGMERKDLLTANGQI 110
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 34.7 bits (76), Expect = 0.94
Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGM-TRDDLFNTNASIVR 419
AA++DAD+ V AG PR P + TR DL N + +
Sbjct: 60 AAMRDADIFVFAAGTPRTPDIKTRADLLEANIPVAK 95
>UniRef50_A3AIZ4 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 547
Score = 34.3 bits (75), Expect = 1.2
Identities = 15/44 (34%), Positives = 19/44 (43%)
Frame = -2
Query: 262 WESRLRRRGSQALCRIKPAWSPEDSASVEGPKAGRYHRRHQRPP 131
W R+ GS+ + WSP S GR RR +RPP
Sbjct: 459 WRERMAAAGSRRRRSARRRWSPPGRCSASTTAGGRCQRRRRRPP 502
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 33.1 bits (72), Expect = 2.9
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +1
Query: 103 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP 231
++++ RN K G+ LAL LKQ+ L+ LA+YD P
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP 71
>UniRef50_Q1MXW3 Cluster: TonB-dependent receptor; n=1; Oceanobacter
sp. RED65|Rep: TonB-dependent receptor - Oceanobacter
sp. RED65
Length = 1005
Score = 33.1 bits (72), Expect = 2.9
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +3
Query: 270 TPAKVSGTRDLRSYQAAIKDADVXVIPAG 356
TPAK SG ++ ++ A I AD+ V+PAG
Sbjct: 541 TPAKRSGESEITAWDATISTADLFVLPAG 569
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 33.1 bits (72), Expect = 2.9
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI 437
I D+DV I AG+ RKP +R DL N N + I S+
Sbjct: 66 IPDSDVICITAGLRRKPDESRLDLINRNVDLFLSILDSV 104
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 33.1 bits (72), Expect = 2.9
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +3
Query: 321 IKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
+ ADV ++ GV +KPG +R +L + NA + R + + + A
Sbjct: 56 LSGADVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAA 98
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 32.7 bits (71), Expect = 3.8
Identities = 17/42 (40%), Positives = 19/42 (45%)
Frame = +3
Query: 318 AIKDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 443
A+ A V G RK GMTR+DL NA I I Q
Sbjct: 71 ALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQ 112
>UniRef50_Q5QU95 Cluster: Uncharacterized conserved secreted
protein; n=1; Idiomarina loihiensis|Rep: Uncharacterized
conserved secreted protein - Idiomarina loihiensis
Length = 771
Score = 32.7 bits (71), Expect = 3.8
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +3
Query: 177 STEAESSGDQAGFIRHSACDPRRRSRLSHMNTPAKV 284
+TEA+S G++ + DP RR+ +SH+ P KV
Sbjct: 586 NTEAKSKGNKHKRVMRENADPNRRNVVSHLKMPKKV 621
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 32.7 bits (71), Expect = 3.8
Identities = 15/34 (44%), Positives = 17/34 (50%)
Frame = +3
Query: 312 QAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASI 413
+ A KD DV + PRK GM R DL N I
Sbjct: 56 EEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGI 89
>UniRef50_A4I4B9 Cluster: Flagellar radial spoke protein-like,
putative; n=3; Leishmania|Rep: Flagellar radial spoke
protein-like, putative - Leishmania infantum
Length = 702
Score = 32.7 bits (71), Expect = 3.8
Identities = 22/70 (31%), Positives = 35/70 (50%)
Frame = +3
Query: 129 SGGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRLSHMNTPAKVSGTRDLRS 308
+GGR RRW RP+ P+ EA + + + ++ DP +RL + +P ++ R LR
Sbjct: 346 AGGRLARRWPRPS-APAEEAGTGLNAMCYYASTSADPTTWTRLPDV-SPHHITVARALRC 403
Query: 309 YQAAIKDADV 338
DA V
Sbjct: 404 RFTGNLDAPV 413
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 32.7 bits (71), Expect = 3.8
Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Frame = +3
Query: 315 AAIKDADVXVIPAGVPRKPGM-TRDDLFNTNASIVRD 422
A +KDAD + AG R P + TR DLF+ N I ++
Sbjct: 59 ADLKDADYCIFSAGYSRSPNIKTRADLFDKNLPIAKE 95
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 3.8
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -2
Query: 139 RPPL*SSSVMWWKSSLHHFVQQ 74
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
>UniRef50_A2QKB8 Cluster: Contig An04c0370, complete genome; n=1;
Aspergillus niger|Rep: Contig An04c0370, complete genome
- Aspergillus niger
Length = 843
Score = 32.3 bits (70), Expect = 5.0
Identities = 18/68 (26%), Positives = 28/68 (41%)
Frame = -2
Query: 262 WESRLRRRGSQALCRIKPAWSPEDSASVEGPKAGRYHRRHQRPPL*SSSVMWWKSSLHHF 83
W S+LR R S + + A DS G G+ R R ++ W+++L
Sbjct: 701 WPSKLRARASSKIATVSTATQQVDSQRDHGDPDGQEIGREDREDSEDVELLGWRTTLIER 760
Query: 82 VQQGRQVL 59
QGR +
Sbjct: 761 AGQGRPTI 768
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 32.3 bits (70), Expect = 5.0
Identities = 15/34 (44%), Positives = 20/34 (58%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
K+AD+ I AG +KPG TR DL N I + +
Sbjct: 73 KEADIVCICAGANQKPGETRLDLVEKNLKIFKSL 106
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 31.9 bits (69), Expect = 6.6
Identities = 15/32 (46%), Positives = 21/32 (65%)
Frame = +1
Query: 160 GQPLALLLKQNPLVTRLALYDIAPVTPGVAAD 255
G L+L LKQ+PL+ LA++D T G+A D
Sbjct: 13 GNCLSLFLKQSPLIDELAIFDNNSSTYGLALD 44
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 31.9 bits (69), Expect = 6.6
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +3
Query: 330 ADVXVIPAGVPRKPGMTRDDLFNTNASIVRDI 425
AD+ VI AG+PRK R L + NA+++ D+
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADL 99
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 31.9 bits (69), Expect = 6.6
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = +3
Query: 282 VSGTRDLRSYQAAIKDADVXVIPAGVPRKPGMTRDDLFNTNASI 413
V GT DL + A +D DV + P+KP D F NASI
Sbjct: 67 VIGTSDL---EEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASI 107
>UniRef50_Q47706 Cluster: Membrane-associated protein uidC
precursor; n=22; Enterobacteriaceae|Rep:
Membrane-associated protein uidC precursor - Escherichia
coli (strain K12)
Length = 421
Score = 31.9 bits (69), Expect = 6.6
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Frame = +2
Query: 71 PLLYKMVQRTFPPHHRGTLKWWSLVPPVVSASLWPFY*SRI-LW 199
PL+ QRT P G L +W+L P + LW + SR+ LW
Sbjct: 141 PLMAGSSQRTLPTVSEGALGYWALTPNI---DLWGMWRSRVFLW 181
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 31.9 bits (69), Expect = 6.6
Identities = 15/32 (46%), Positives = 17/32 (53%)
Frame = +3
Query: 318 AIKDADVXVIPAGVPRKPGMTRDDLFNTNASI 413
A KD D ++ PR PGM R DL NA I
Sbjct: 80 AFKDTDYALLVGARPRGPGMERADLLAANAQI 111
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 31.5 bits (68), Expect = 8.8
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = +1
Query: 91 AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADF 258
+++F + Q++ + +GQ LA L+KQNP ++ L L + V +A DF
Sbjct: 11 SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKV-ESMALDF 65
>UniRef50_UPI00015A6833 Cluster: hypothetical protein LOC572435; n=2;
Danio rerio|Rep: hypothetical protein LOC572435 - Danio
rerio
Length = 1641
Score = 31.5 bits (68), Expect = 8.8
Identities = 23/86 (26%), Positives = 36/86 (41%)
Frame = +3
Query: 165 AFGPSTEAESSGDQAGFIRHSACDPRRRSRLSHMNTPAKVSGTRDLRSYQAAIKDADVXV 344
+F +E GD G P R+S M T + G+RD + +K
Sbjct: 1217 SFSRESEERRGGDNRG-------PPDSVRRVSSM-TDNRDRGSRDRDRSKETVKPMAAPA 1268
Query: 345 IPAGVPRKPGMTRDDLFNTNASIVRD 422
+P P KP M+ +DL + SI+ +
Sbjct: 1269 LPPPAPVKPAMSEEDLDKKSKSIIEE 1294
>UniRef50_Q0RVX2 Cluster: Putative uncharacterized protein; n=1;
Rhodococcus sp. RHA1|Rep: Putative uncharacterized
protein - Rhodococcus sp. (strain RHA1)
Length = 198
Score = 31.5 bits (68), Expect = 8.8
Identities = 18/61 (29%), Positives = 29/61 (47%)
Frame = +3
Query: 144 CRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRLSHMNTPAKVSGTRDLRSYQAAI 323
CRR YR A+ P+T S + C PRR + ++P ++ GT R +Q +
Sbjct: 67 CRR-YRTAWSPATRPSSPHSRCRMRTTGMCWPRRSAPAPRSSSP-RICGTSPTRIWQFGV 124
Query: 324 K 326
+
Sbjct: 125 E 125
>UniRef50_Q41068 Cluster: P.sativum vicilin; n=1; Pisum sativum|Rep:
P.sativum vicilin - Pisum sativum (Garden pea)
Length = 63
Score = 31.5 bits (68), Expect = 8.8
Identities = 20/48 (41%), Positives = 28/48 (58%)
Frame = +3
Query: 219 RHSACDPRRRSRLSHMNTPAKVSGTRDLRSYQAAIKDADVXVIPAGVP 362
R S D R++S+ N KVS + ++SY+A + DV VIPAG P
Sbjct: 17 RRSLRDKRQQSQ--EKNVIVKVS--KQVQSYKAKLTPGDVFVIPAGHP 60
>UniRef50_Q4N5S4 Cluster: Putative uncharacterized protein; n=1;
Theileria parva|Rep: Putative uncharacterized protein -
Theileria parva
Length = 1298
Score = 31.5 bits (68), Expect = 8.8
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 3/38 (7%)
Frame = -2
Query: 235 SQALCRIKPAWSPEDSASVEGPKAGR---YHRRHQRPP 131
S + C I+P+ SP+ S + +G + G YH +H +PP
Sbjct: 929 SDSDCDIQPSCSPQQSGTEQGAQQGAQNVYHYQHYQPP 966
>UniRef50_A2QN02 Cluster: Putative uncharacterized protein
precursor; n=1; Aspergillus niger|Rep: Putative
uncharacterized protein precursor - Aspergillus niger
Length = 288
Score = 31.5 bits (68), Expect = 8.8
Identities = 17/43 (39%), Positives = 19/43 (44%)
Frame = -1
Query: 332 SIFDGCLIAPQVPCAADLGWGVHVGKSAATPGVTGAMSYKASL 204
S F GC+ AP VPC L G A + A S ASL
Sbjct: 197 SYFQGCVTAPPVPCGQTLFIGPLTATLGANVSASAAASSSASL 239
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 31.5 bits (68), Expect = 8.8
Identities = 15/42 (35%), Positives = 26/42 (61%)
Frame = +3
Query: 324 KDADVXVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 449
+DAD+ VI AG +KPG +R +L +I++ I ++ + A
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVA 116
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 480,590,658
Number of Sequences: 1657284
Number of extensions: 10487659
Number of successful extensions: 28943
Number of sequences better than 10.0: 108
Number of HSP's better than 10.0 without gapping: 27972
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28928
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 23604537544
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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