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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= msgV0671.Seq
         (449 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

DQ403082-1|ABD77215.1|  371|Homo sapiens isocitrate dehydrogenas...   140   2e-33
CR541695-1|CAG46496.1|  414|Homo sapiens IDH1 protein.                140   2e-33
CR536499-1|CAG38738.1|  414|Homo sapiens IDH1 protein.                140   2e-33
CR533522-1|CAG38553.1|  414|Homo sapiens IDH1 protein.                140   2e-33
BX537411-1|CAD97653.1|  414|Homo sapiens hypothetical protein pr...   140   2e-33
BC093020-1|AAH93020.1|  414|Homo sapiens isocitrate dehydrogenas...   140   2e-33
BC012846-1|AAH12846.1|  414|Homo sapiens IDH1 protein protein.        140   2e-33
AF113917-1|AAD29284.1|  414|Homo sapiens NADP+-dependent isocitr...   140   2e-33
AF020038-1|AAD02918.1|  414|Homo sapiens NADP-dependent isocitra...   140   2e-33
AC016697-3|AAX93221.1|  414|Homo sapiens unknown protein.             140   2e-33
X69433-1|CAA49208.1|  452|Homo sapiens isocitrate  dehydrogenase...   137   2e-32
U52144-1|AAC50455.1|  419|Homo sapiens isocitrate dehydrogenase ...   137   2e-32
BC071828-1|AAH71828.1|  452|Homo sapiens isocitrate dehydrogenas...   137   2e-32
BC009244-1|AAH09244.1|  452|Homo sapiens isocitrate dehydrogenas...   137   2e-32
AK222916-1|BAD96636.1|  452|Homo sapiens isocitrate dehydrogenas...   135   6e-32
U62389-1|AAB17375.1|  154|Homo sapiens putative cytosolic NADP-d...   128   1e-29

>DQ403082-1|ABD77215.1|  371|Homo sapiens isocitrate dehydrogenase 1
           protein.
          Length = 371

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 114 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 173

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 174 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 233

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 234 GGFIWAC 240



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 240 CKNYDGDVQSDSVAQGYGSLGMM 262


>CR541695-1|CAG46496.1|  414|Homo sapiens IDH1 protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>CR536499-1|CAG38738.1|  414|Homo sapiens IDH1 protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>CR533522-1|CAG38553.1|  414|Homo sapiens IDH1 protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>BX537411-1|CAD97653.1|  414|Homo sapiens hypothetical protein
           protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 84/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDXKTPG--VAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L      G  VAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>BC093020-1|AAH93020.1|  414|Homo sapiens isocitrate dehydrogenase 1
           (NADP+), soluble protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>BC012846-1|AAH12846.1|  414|Homo sapiens IDH1 protein protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>AF113917-1|AAD29284.1|  414|Homo sapiens NADP+-dependent isocitrate
           dehydrogenase protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>AF020038-1|AAD02918.1|  414|Homo sapiens NADP-dependent isocitrate
           dehydrogenase protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>AC016697-3|AAX93221.1|  414|Homo sapiens unknown protein.
          Length = 414

 Score =  140 bits (340), Expect = 2e-33
 Identities = 70/127 (55%), Positives = 85/127 (66%), Gaps = 5/127 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 143 DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 202

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK-- 352
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDDMV QA+K  
Sbjct: 203 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSE 262

Query: 353 -GSMWXC 370
            G +W C
Sbjct: 263 GGFIWAC 269



 Score = 33.1 bits (72), Expect = 0.45
 Identities = 15/23 (65%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    VA GY SLGMM
Sbjct: 269 CKNYDGDVQSDSVAQGYGSLGMM 291


>X69433-1|CAA49208.1|  452|Homo sapiens isocitrate  dehydrogenase
           (NADP+) protein.
          Length = 452

 Score =  137 bits (331), Expect = 2e-32
 Identities = 65/126 (51%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERR-VLYDXKTPGVAMGMYNTDESIRSFAHSSFQVALQK 181
           DFV  + G  ++V+T +DG+  +   +Y+    GV MGMYNTDESI  FAHS FQ A+QK
Sbjct: 183 DFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK 242

Query: 182 KWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK--- 352
           KWPLY+ST+    +     F+  FQE+F   YKT FD+ KIWYEHRLIDDMV Q +K   
Sbjct: 243 KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSG 302

Query: 353 GSMWXC 370
           G +W C
Sbjct: 303 GFVWAC 308



 Score = 29.9 bits (64), Expect = 4.2
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    +A G+ SLG+M
Sbjct: 308 CKNYDGDVQSDILAQGFGSLGLM 330


>U52144-1|AAC50455.1|  419|Homo sapiens isocitrate dehydrogenase
           protein.
          Length = 419

 Score =  137 bits (331), Expect = 2e-32
 Identities = 65/126 (51%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERR-VLYDXKTPGVAMGMYNTDESIRSFAHSSFQVALQK 181
           DFV  + G  ++V+T +DG+  +   +Y+    GV MGMYNTDESI  FAHS FQ A+QK
Sbjct: 150 DFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK 209

Query: 182 KWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK--- 352
           KWPLY+ST+    +     F+  FQE+F   YKT FD+ KIWYEHRLIDDMV Q +K   
Sbjct: 210 KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSG 269

Query: 353 GSMWXC 370
           G +W C
Sbjct: 270 GFVWAC 275



 Score = 29.9 bits (64), Expect = 4.2
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    +A G+ SLG+M
Sbjct: 275 CKNYDGDVQSDILAQGFGSLGLM 297


>BC071828-1|AAH71828.1|  452|Homo sapiens isocitrate dehydrogenase 2
           (NADP+), mitochondrial protein.
          Length = 452

 Score =  137 bits (331), Expect = 2e-32
 Identities = 65/126 (51%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERR-VLYDXKTPGVAMGMYNTDESIRSFAHSSFQVALQK 181
           DFV  + G  ++V+T +DG+  +   +Y+    GV MGMYNTDESI  FAHS FQ A+QK
Sbjct: 183 DFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK 242

Query: 182 KWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK--- 352
           KWPLY+ST+    +     F+  FQE+F   YKT FD+ KIWYEHRLIDDMV Q +K   
Sbjct: 243 KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSG 302

Query: 353 GSMWXC 370
           G +W C
Sbjct: 303 GFVWAC 308



 Score = 29.9 bits (64), Expect = 4.2
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    +A G+ SLG+M
Sbjct: 308 CKNYDGDVQSDILAQGFGSLGLM 330


>BC009244-1|AAH09244.1|  452|Homo sapiens isocitrate dehydrogenase 2
           (NADP+), mitochondrial protein.
          Length = 452

 Score =  137 bits (331), Expect = 2e-32
 Identities = 65/126 (51%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERR-VLYDXKTPGVAMGMYNTDESIRSFAHSSFQVALQK 181
           DFV  + G  ++V+T +DG+  +   +Y+    GV MGMYNTDESI  FAHS FQ A+QK
Sbjct: 183 DFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK 242

Query: 182 KWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK--- 352
           KWPLY+ST+    +     F+  FQE+F   YKT FD+ KIWYEHRLIDDMV Q +K   
Sbjct: 243 KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSG 302

Query: 353 GSMWXC 370
           G +W C
Sbjct: 303 GFVWAC 308



 Score = 29.9 bits (64), Expect = 4.2
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    +A G+ SLG+M
Sbjct: 308 CKNYDGDVQSDILAQGFGSLGLM 330


>AK222916-1|BAD96636.1|  452|Homo sapiens isocitrate dehydrogenase 2
           (NADP+), mitochondrial precursor variant protein.
          Length = 452

 Score =  135 bits (327), Expect = 6e-32
 Identities = 64/126 (50%), Positives = 83/126 (65%), Gaps = 4/126 (3%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERR-VLYDXKTPGVAMGMYNTDESIRSFAHSSFQVALQK 181
           DFV  + G  ++V+T +DG+  +   +Y+    GV MGMYNTDESI  FAHS FQ A+QK
Sbjct: 183 DFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK 242

Query: 182 KWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDDMVXQAIK--- 352
           KWPLY+ST+    +     F+  FQE+F   Y+T FD+ KIWYEHRLIDDMV Q +K   
Sbjct: 243 KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYETDFDKNKIWYEHRLIDDMVAQVLKSSG 302

Query: 353 GSMWXC 370
           G +W C
Sbjct: 303 GFVWAC 308



 Score = 29.9 bits (64), Expect = 4.2
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +1

Query: 379 CXNYDGYVSPIFVAHGYXSLGMM 447
           C NYDG V    +A G+ SLG+M
Sbjct: 308 CKNYDGDVQSDILAQGFGSLGLM 330


>U62389-1|AAB17375.1|  154|Homo sapiens putative cytosolic
           NADP-dependent isocitrate dehydrogenase protein.
          Length = 154

 Score =  128 bits (308), Expect = 1e-29
 Identities = 62/111 (55%), Positives = 75/111 (67%), Gaps = 2/111 (1%)
 Frame = +2

Query: 5   DFVVPKPGKVELVYTTRDGTTERRVLYDX--KTPGVAMGMYNTDESIRSFAHSSFQVALQ 178
           DFVVP PGKVE+ YT  DGT +   L     +  GVAMGMYN D+SI  FAHSSFQ+AL 
Sbjct: 44  DFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS 103

Query: 179 KKWPLYLSTEEYHFETLRWSFQRHFQEVFQSDYKTKFDEAKIWYEHRLIDD 331
           K WPLYLST+    +     F+  FQE++   YK++F+  KIWYEHRLIDD
Sbjct: 104 KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 62,784,312
Number of Sequences: 237096
Number of extensions: 1142391
Number of successful extensions: 2158
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 2061
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2126
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 3701294870
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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