Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= msgV0641.Seq
(499 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4D8F Cluster: PREDICTED: similar to DNA topois... 175 5e-43
UniRef50_UPI0000E21D0D Cluster: PREDICTED: similar to topoisomer... 168 5e-41
UniRef50_UPI0000F2147E Cluster: PREDICTED: similar to mitochondr... 165 4e-40
UniRef50_P11387 Cluster: DNA topoisomerase 1; n=73; Eumetazoa|Re... 165 4e-40
UniRef50_P30189 Cluster: DNA topoisomerase 1; n=7; Endopterygota... 160 1e-38
UniRef50_Q4SR65 Cluster: Chromosome 11 SCAF14528, whole genome s... 155 4e-37
UniRef50_A4S5R8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 142 5e-33
UniRef50_P04786 Cluster: DNA topoisomerase 1; n=35; Ascomycota|R... 138 8e-32
UniRef50_Q4Q2K0 Cluster: DNA topoisomerase IB, large subunit; n=... 127 1e-28
UniRef50_P30181 Cluster: DNA topoisomerase 1; n=17; Magnoliophyt... 126 2e-28
UniRef50_UPI0000F31E2F Cluster: DNA topoisomerase I, mitochondri... 124 1e-27
UniRef50_Q54RC3 Cluster: Putative uncharacterized protein; n=1; ... 121 1e-26
UniRef50_Q5KB99 Cluster: Topoisomerase I; n=10; Filobasidiella n... 118 6e-26
UniRef50_Q5CY81 Cluster: Eukaryotic DNA topoisomerase I; n=2; Cr... 118 7e-26
UniRef50_UPI0000E471B7 Cluster: PREDICTED: similar to topoisomer... 116 2e-25
UniRef50_Q94705 Cluster: DNA topoisomerase I; n=2; Eukaryota|Rep... 110 2e-23
UniRef50_Q26024 Cluster: Topoisomerase I; n=4; Plasmodium|Rep: T... 103 2e-21
UniRef50_A5KB33 Cluster: Topoisomerase I, putative; n=2; Plasmod... 102 4e-21
UniRef50_P41511 Cluster: DNA topoisomerase 1; n=1; Ustilago mayd... 100 2e-20
UniRef50_Q4N5U3 Cluster: DNA topoisomerase I, putative; n=2; The... 99 6e-20
UniRef50_A7AUT4 Cluster: DNA topoisomerase; n=1; Babesia bovis|R... 94 2e-18
UniRef50_A0CF77 Cluster: Chromosome undetermined scaffold_174, w... 92 7e-18
UniRef50_Q24BB2 Cluster: Eukaryotic DNA topoisomerase I, catalyt... 89 4e-17
UniRef50_A7DNZ3 Cluster: 2-alkenal reductase; n=1; Candidatus Ni... 88 9e-17
UniRef50_A0RU10 Cluster: DNA topoisomerase IB; n=1; Cenarchaeum ... 83 3e-15
UniRef50_P93119 Cluster: DNA topoisomerase 1; n=1; Daucus carota... 79 7e-14
UniRef50_O58143 Cluster: Putative uncharacterized protein PH0406... 35 1.2
UniRef50_Q8FP72 Cluster: Putative uncharacterized protein; n=1; ... 32 8.2
>UniRef50_UPI00015B4D8F Cluster: PREDICTED: similar to DNA
topoisomerase type I; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to DNA topoisomerase type I - Nasonia
vitripennis
Length = 1019
Score = 175 bits (426), Expect = 5e-43
Identities = 73/90 (81%), Positives = 81/90 (90%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
QKEYG CTIDGHKEKIGNF+IEPPGLFRGRGEHPKMGKLK+R++PEDVLINCSKDS PK
Sbjct: 591 QKEYGICTIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRLVPEDVLINCSKDSVHPK 650
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP GHKW+E+RHD TVTWLASWTE ++
Sbjct: 651 PPPGHKWKEIRHDPTVTWLASWTENIQGQV 680
Score = 130 bits (313), Expect = 2e-29
Identities = 59/78 (75%), Positives = 67/78 (85%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+Q Q KYVMLNPSSKLKGEKDWQKYETARKL K +DKIR R DWK+KEM++ QRAVAL
Sbjct: 676 IQGQVKYVMLNPSSKLKGEKDWQKYETARKLAKSVDKIRATYREDWKSKEMRIRQRAVAL 735
Query: 435 YFIDRLALTAXNEKDDEQ 488
YFID+LAL A NEKD++Q
Sbjct: 736 YFIDKLALRAGNEKDEDQ 753
>UniRef50_UPI0000E21D0D Cluster: PREDICTED: similar to topoisomerase
I; n=1; Pan troglodytes|Rep: PREDICTED: similar to
topoisomerase I - Pan troglodytes
Length = 1363
Score = 168 bits (409), Expect = 5e-41
Identities = 66/90 (73%), Positives = 83/90 (92%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G+C +DGH+EKIGNF+IEPPGLFRGRG+HPKMG LKRR+MPEDV+INCS+DSKIP+
Sbjct: 463 QREFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRIMPEDVVINCSRDSKIPE 522
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP+GH+W+EVR DNTVTWLA+WTE + +
Sbjct: 523 PPAGHQWKEVRSDNTVTWLAAWTESVQNSI 552
Score = 96.3 bits (229), Expect = 3e-19
Identities = 42/66 (63%), Positives = 52/66 (78%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
VQ KY+MLNP SKLKGE WQK+ETAR+L +D+IR RADWK++EM+ QRAVAL
Sbjct: 548 VQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVAL 607
Query: 435 YFIDRL 452
YFID++
Sbjct: 608 YFIDKV 613
>UniRef50_UPI0000F2147E Cluster: PREDICTED: similar to mitochondrial
topoisomerase I, partial; n=3; Danio rerio|Rep:
PREDICTED: similar to mitochondrial topoisomerase I,
partial - Danio rerio
Length = 492
Score = 165 bits (402), Expect = 4e-40
Identities = 64/88 (72%), Positives = 79/88 (89%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
+E+G+C +DGH+EKIGNF++EPPGLFRGRGEHPKMG+LK+R+ PEDV INCSKDSKIP+P
Sbjct: 384 EEFGYCLLDGHREKIGNFKLEPPGLFRGRGEHPKMGRLKKRIQPEDVAINCSKDSKIPEP 443
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSK 267
P+GHKW+ V+HDNTVTWLASW E +
Sbjct: 444 PAGHKWKRVQHDNTVTWLASWLENIQKR 471
Score = 32.3 bits (70), Expect = 6.2
Identities = 14/27 (51%), Positives = 22/27 (81%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLK 305
+++ S L+ +Q++ KY+MLNPSSKLK
Sbjct: 459 TWLASWLEN-IQKRPKYIMLNPSSKLK 484
>UniRef50_P11387 Cluster: DNA topoisomerase 1; n=73; Eumetazoa|Rep:
DNA topoisomerase 1 - Homo sapiens (Human)
Length = 765
Score = 165 bits (402), Expect = 4e-40
Identities = 65/89 (73%), Positives = 75/89 (84%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPKMG LKRR+MPED++INCSKD+K+P P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 395
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 396 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 424
Score = 125 bits (301), Expect = 6e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 411 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 469
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 470 MKVRQRAVALYFIDKLALRAGNEKEE 495
>UniRef50_P30189 Cluster: DNA topoisomerase 1; n=7;
Endopterygota|Rep: DNA topoisomerase 1 - Drosophila
melanogaster (Fruit fly)
Length = 972
Score = 160 bits (389), Expect = 1e-38
Identities = 65/89 (73%), Positives = 74/89 (83%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KE+GFC IDGHKEKIGNFR+EPPGLFRGRGEHPKMG +KRR+ DV INC KDSK+P P
Sbjct: 559 KEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSP 618
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P G +W+EVRHDNTVTWLASW E ++
Sbjct: 619 PPGSRWKEVRHDNTVTWLASWIENVQGQV 647
Score = 119 bits (287), Expect = 3e-26
Identities = 57/78 (73%), Positives = 65/78 (83%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
VQ Q KY+MLNPSSKLKGEKD KYETAR+L K IDKIR R +WK+KEM+V QRAVAL
Sbjct: 643 VQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVAL 702
Query: 435 YFIDRLALTAXNEKDDEQ 488
YFID+LAL A NEKD++Q
Sbjct: 703 YFIDKLALRAGNEKDEDQ 720
>UniRef50_Q4SR65 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 11
SCAF14528, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 806
Score = 155 bits (377), Expect = 4e-37
Identities = 61/89 (68%), Positives = 74/89 (83%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
+++GFC +D HKE+I NFRIEPPGLFRGRG+HPKMG LKRR+ PED++INCSKDSK P+P
Sbjct: 327 QQFGFCIMDNHKERIANFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKYPEP 386
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P G +W+EVRHDN VTWL SWTE +
Sbjct: 387 PPGTRWKEVRHDNKVTWLVSWTENIQGSI 415
Score = 123 bits (297), Expect = 2e-27
Identities = 54/86 (62%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+D+IR R DWK+KE
Sbjct: 402 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKE 460
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M++ QRAVALYFID+LAL A NEK++
Sbjct: 461 MRIRQRAVALYFIDKLALRAGNEKEE 486
>UniRef50_A4S5R8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 491
Score = 142 bits (343), Expect = 5e-33
Identities = 55/89 (61%), Positives = 73/89 (82%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
++ Y + TIDG +EK+GNFR+EPPGLFRGRGEHPKMGK+KRRV+PED+ IN KD+K+P+
Sbjct: 73 EEPYTWATIDGRREKVGNFRVEPPGLFRGRGEHPKMGKIKRRVVPEDITINIGKDAKVPE 132
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSK 267
PP+GH W+ V H++T TWLA W + + K
Sbjct: 133 PPAGHSWKAVIHNDTATWLAGWNDVINVK 161
Score = 70.5 bits (165), Expect = 2e-11
Identities = 32/72 (44%), Positives = 48/72 (66%)
Frame = +3
Query: 270 KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYFIDR 449
KYV +S +K E D +KYE AR LHK I+KIR++ + + ++ ++ Q AVA Y +D+
Sbjct: 164 KYVQFGATSTVKAESDQKKYEKARSLHKYIEKIRKDYKRNMMSESKEMAQLAVATYLVDK 223
Query: 450 LALTAXNEKDDE 485
LAL A EKD++
Sbjct: 224 LALRAGGEKDED 235
>UniRef50_P04786 Cluster: DNA topoisomerase 1; n=35; Ascomycota|Rep:
DNA topoisomerase 1 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 769
Score = 138 bits (333), Expect = 8e-32
Identities = 53/84 (63%), Positives = 68/84 (80%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
+++Y FC +DG +E++GNF++EPP LFRGRG HPK GKLKRRV PED+++N SKD+ +P
Sbjct: 267 EEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPP 326
Query: 181 PPSGHKWREVRHDNTVTWLASWTE 252
P GHKW E+RHDNTV WLA W E
Sbjct: 327 APEGHKWGEIRHDNTVQWLAMWRE 350
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/73 (45%), Positives = 47/73 (64%)
Frame = +3
Query: 270 KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYFIDR 449
KYV L +S LKG+ D++K+E AR+L ID IR + + K+K M Q+AVA+Y ID
Sbjct: 357 KYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDV 416
Query: 450 LALTAXNEKDDEQ 488
AL A EK +++
Sbjct: 417 FALRAGGEKSEDE 429
>UniRef50_Q4Q2K0 Cluster: DNA topoisomerase IB, large subunit; n=12;
Trypanosomatidae|Rep: DNA topoisomerase IB, large
subunit - Leishmania major
Length = 634
Score = 127 bits (307), Expect = 1e-28
Identities = 49/87 (56%), Positives = 66/87 (75%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKPPS 189
Y +C DG +E++ NFR+EPPGLFRGRG+HP MGKLK RV PED+ IN + +++P PP+
Sbjct: 164 YRYCVWDGRREQVANFRVEPPGLFRGRGKHPLMGKLKVRVQPEDITINIGETAEVPVPPA 223
Query: 190 GHKWREVRHDNTVTWLASWTEKFSSKL 270
GHKW V+HD+TVTWLA W + + +
Sbjct: 224 GHKWAAVQHDHTVTWLAMWRDNVAGNM 250
Score = 80.2 bits (189), Expect = 2e-14
Identities = 38/73 (52%), Positives = 51/73 (69%)
Frame = +3
Query: 270 KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYFIDR 449
KYVML PSS +KG+ D K+E ARKL +D IR + +K+ ++ V QRAVA+YFIDR
Sbjct: 251 KYVMLAPSSSVKGQSDMVKFEKARKLKDKVDDIRASYMEAFKSNDLHVAQRAVAMYFIDR 310
Query: 450 LALTAXNEKDDEQ 488
LAL NEK +++
Sbjct: 311 LALRVGNEKGEDE 323
>UniRef50_P30181 Cluster: DNA topoisomerase 1; n=17;
Magnoliophyta|Rep: DNA topoisomerase 1 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 916
Score = 126 bits (305), Expect = 2e-28
Identities = 52/90 (57%), Positives = 71/90 (78%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
+++Y + +DG KEKIGNFR+EPPGLFRGRGEHPKMGKLK+R+ P ++ +N K + IP+
Sbjct: 485 EEKYMWAVVDGVKEKIGNFRVEPPGLFRGRGEHPKMGKLKKRIHPCEITLNIGKGAPIPE 544
Query: 181 -PPSGHKWREVRHDNTVTWLASWTEKFSSK 267
P +G +W+EV+HDNTVTWLA W + + K
Sbjct: 545 CPIAGERWKEVKHDNTVTWLAFWADPINPK 574
Score = 72.9 bits (171), Expect = 4e-12
Identities = 37/76 (48%), Positives = 49/76 (64%)
Frame = +3
Query: 261 QQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYF 440
++ KYV L S LKG D +KYE AR L ID IR ++ AK++++ Q AVA Y
Sbjct: 574 KEFKYVFLGAGSSLKGLSDKEKYEKARNLTDHIDNIRTTYTKNFTAKDVKMRQIAVATYL 633
Query: 441 IDRLALTAXNEKDDEQ 488
ID+LAL A NEKDD++
Sbjct: 634 IDKLALRAGNEKDDDE 649
>UniRef50_UPI0000F31E2F Cluster: DNA topoisomerase I, mitochondrial
precursor (EC 5.99.1.2) (TOP1mt).; n=3; Bos taurus|Rep:
DNA topoisomerase I, mitochondrial precursor (EC
5.99.1.2) (TOP1mt). - Bos Taurus
Length = 623
Score = 124 bits (298), Expect = 1e-27
Identities = 52/84 (61%), Positives = 70/84 (83%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G +DGH+EKIG+F+ EP + RGRG+HPKM +LKRRV+PEDV+INCS+DS +P+
Sbjct: 123 QQEFGCSILDGHREKIGSFKTEPLSV-RGRGDHPKMERLKRRVLPEDVVINCSRDSTVPE 181
Query: 181 PPSGHKWREVRHDNTVTWLASWTE 252
PP+G +W+EV D TV WLA+WTE
Sbjct: 182 PPAGPQWKEVGCDCTVMWLAAWTE 205
Score = 76.2 bits (179), Expect = 4e-13
Identities = 38/75 (50%), Positives = 47/75 (62%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
VQ KYV LNP KLKGE+DW KYE A +L + KI R + EM+ QRAVAL
Sbjct: 207 VQNFIKYVTLNPGCKLKGERDWGKYEAAWRLKGAVGKICSQYRTAGTSPEMRTRQRAVAL 266
Query: 435 YFIDRLALTAXNEKD 479
YFI++LAL N ++
Sbjct: 267 YFINKLALQTGNGEE 281
>UniRef50_Q54RC3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 893
Score = 121 bits (291), Expect = 1e-26
Identities = 51/85 (60%), Positives = 64/85 (75%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+++GF TIDG KEK+GN+ IEPPGLF GRG+HPK G LK+R+MP DV +N + IP
Sbjct: 428 QEKHGFATIDGFKEKVGNYMIEPPGLFLGRGQHPKTGMLKQRIMPSDVTLNIGEGEVIPP 487
Query: 181 PP-SGHKWREVRHDNTVTWLASWTE 252
P G KW+E+ H+NTVTWLA W E
Sbjct: 488 SPIPGEKWKEIVHNNTVTWLAFWRE 512
Score = 69.7 bits (163), Expect = 3e-11
Identities = 35/73 (47%), Positives = 46/73 (63%)
Frame = +3
Query: 270 KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYFIDR 449
KYV L PSSK+KG+ D +K+E AR L CI IR+ + + + + Q AVALY ID
Sbjct: 519 KYVWLAPSSKIKGQADRKKFEVARGLKNCIGDIRKGYQKSFNDESTEKRQLAVALYLIDF 578
Query: 450 LALTAXNEKDDEQ 488
LAL NEK ++Q
Sbjct: 579 LALRVGNEKGEDQ 591
>UniRef50_Q5KB99 Cluster: Topoisomerase I; n=10; Filobasidiella
neoformans|Rep: Topoisomerase I - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 881
Score = 118 bits (285), Expect = 6e-26
Identities = 47/81 (58%), Positives = 61/81 (75%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKPPS 189
Y + +DG KEK+GNFR EPPGLF+GRGEHPK G +K R+ PED++IN K++ IP P
Sbjct: 383 YLYANVDGRKEKVGNFRAEPPGLFKGRGEHPKKGTVKNRLRPEDIIINIGKEAPIPVPNI 442
Query: 190 GHKWREVRHDNTVTWLASWTE 252
+W+ ++HDNTVTWLA W E
Sbjct: 443 PGQWKGIQHDNTVTWLAHWKE 463
Score = 81.4 bits (192), Expect = 1e-14
Identities = 42/78 (53%), Positives = 53/78 (67%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
V AKYV L+ S KG+ D K+E AR+L K +DKIR++ AD K+K M QRA AL
Sbjct: 465 VNGNAKYVFLSAGSAWKGQSDRAKFEKARELIKHVDKIRKDYTADLKSKVMADRQRATAL 524
Query: 435 YFIDRLALTAXNEKDDEQ 488
YFIDRLAL A NEK +++
Sbjct: 525 YFIDRLALRAGNEKGEDE 542
>UniRef50_Q5CY81 Cluster: Eukaryotic DNA topoisomerase I; n=2;
Cryptosporidium|Rep: Eukaryotic DNA topoisomerase I -
Cryptosporidium parvum Iowa II
Length = 653
Score = 118 bits (284), Expect = 7e-26
Identities = 48/92 (52%), Positives = 69/92 (75%), Gaps = 3/92 (3%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
+ + + +D KEK+GNFRIEPPGLF+GRGEHPK G LKRR+ PEDV +N ++D+ +PK
Sbjct: 174 ESPFVYALVDWIKEKVGNFRIEPPGLFKGRGEHPKSGMLKRRIFPEDVTLNIAEDAPVPK 233
Query: 181 PPS---GHKWREVRHDNTVTWLASWTEKFSSK 267
P+ GH W+++ HDNTVTWLA + + +++
Sbjct: 234 VPNSMKGHAWKDIFHDNTVTWLAYYRDSINNQ 265
Score = 62.5 bits (145), Expect = 5e-09
Identities = 32/78 (41%), Positives = 43/78 (55%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+ Q KY+ L+ SS KG D+ KYE ARKL ID IR++ R + ++ Q A
Sbjct: 262 INNQFKYIFLSASSGFKGMSDYNKYEKARKLKDHIDAIRDDYRKKMTSGDITQRQLGTAT 321
Query: 435 YFIDRLALTAXNEKDDEQ 488
Y ID LAL EKD ++
Sbjct: 322 YLIDFLALRVGGEKDTDE 339
>UniRef50_UPI0000E471B7 Cluster: PREDICTED: similar to topoisomerase
I beta; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to topoisomerase I beta -
Strongylocentrotus purpuratus
Length = 879
Score = 116 bits (280), Expect = 2e-25
Identities = 52/76 (68%), Positives = 63/76 (82%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+Q KYVMLNPSS++KGEKDW KYETARKL + +D+IR R DWK+KEM+V QRAVAL
Sbjct: 534 IQGAIKYVMLNPSSRIKGEKDWAKYETARKLKESVDRIRNEYREDWKSKEMRVRQRAVAL 593
Query: 435 YFIDRLALTAXNEKDD 482
YFID+LAL A NEK++
Sbjct: 594 YFIDKLALRAGNEKEE 609
Score = 83.8 bits (198), Expect = 2e-15
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +1
Query: 118 KRRVMPEDVLINCSKDSKIPKPPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
K+R+ PEDV+INCSKDSK P PP GHKW++V H+N+VTWLASWTE +
Sbjct: 488 KQRIGPEDVIINCSKDSKWPIPPEGHKWKKVIHENSVTWLASWTENIQGAI 538
>UniRef50_Q94705 Cluster: DNA topoisomerase I; n=2; Eukaryota|Rep:
DNA topoisomerase I - Physarum polycephalum (Slime mold)
Length = 1015
Score = 110 bits (264), Expect = 2e-23
Identities = 44/87 (50%), Positives = 61/87 (70%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
++YGF I+GH+++I N+ IE PGLF GRG HPK G +K+R+ ED+ IN K +P+P
Sbjct: 529 QKYGFAMINGHRQRISNWAIERPGLFLGRGAHPKTGLVKKRIEAEDITINIGKGVPVPEP 588
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSS 264
P GHKW +V HD+ V WLA W E ++
Sbjct: 589 PPGHKWCKVVHDDKVAWLAMWKENINN 615
Score = 72.9 bits (171), Expect = 4e-12
Identities = 35/72 (48%), Positives = 49/72 (68%)
Frame = +3
Query: 270 KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYFIDR 449
KYV L+ SS +KG D +K+E ARKL I+KIR+ + ++E++ QRA A+Y IDR
Sbjct: 618 KYVWLHASSAVKGRSDMKKFEVARKLKDHIEKIRKKYLKELGSEELEERQRATAIYLIDR 677
Query: 450 LALTAXNEKDDE 485
LAL NEKD++
Sbjct: 678 LALRVGNEKDED 689
>UniRef50_Q26024 Cluster: Topoisomerase I; n=4; Plasmodium|Rep:
Topoisomerase I - Plasmodium falciparum
Length = 839
Score = 103 bits (248), Expect = 2e-21
Identities = 44/90 (48%), Positives = 62/90 (68%), Gaps = 3/90 (3%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK--- 180
Y + +D +EKI + + EPPGLFRGRGEHPK G LK+R+ PEDV+IN SKD+ +P+
Sbjct: 286 YTYALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPVPRLYD 345
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
GH W ++ HDN VTWLA + + + ++
Sbjct: 346 NMCGHNWGDIYHDNKVTWLAYYKDSINDQI 375
Score = 70.1 bits (164), Expect = 3e-11
Identities = 37/79 (46%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+ Q KY L+ SK KG KD KYE ARKL C+ KIRE+ + K K + Q A+
Sbjct: 371 INDQIKYTFLSAQSKFKGYKDLMKYENARKLKSCVHKIREDYKNKMKNKNIIDKQLGTAV 430
Query: 435 YFIDRLALTAXNEKD-DEQ 488
Y ID LAL EKD DE+
Sbjct: 431 YLIDFLALRVGGEKDIDEE 449
>UniRef50_A5KB33 Cluster: Topoisomerase I, putative; n=2;
Plasmodium|Rep: Topoisomerase I, putative - Plasmodium
vivax
Length = 931
Score = 102 bits (245), Expect = 4e-21
Identities = 45/90 (50%), Positives = 61/90 (67%), Gaps = 3/90 (3%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK--- 180
Y + +D +EKI + + EPPGLFRGRGEHPK G LK+R+ PEDV+IN SKD+ +P+
Sbjct: 320 YTYALVDWIREKISSNKAEPPGLFRGRGEHPKQGLLKKRIFPEDVVINISKDAPVPRLYD 379
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
GH W + HDN VTWLA + + + +L
Sbjct: 380 DMCGHCWGDTYHDNKVTWLAYYKDSINDQL 409
Score = 70.9 bits (166), Expect = 1e-11
Identities = 37/79 (46%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+ Q KY L+ SK KG KD+ KYE ARKL C+ KIRE+ R + K + Q A+
Sbjct: 405 INDQLKYTFLSAQSKFKGYKDFLKYENARKLKSCVHKIREDYRHKMRNKSILDKQLGTAV 464
Query: 435 YFIDRLALTAXNEKD-DEQ 488
Y ID LAL EKD DE+
Sbjct: 465 YLIDFLALRVGGEKDIDEE 483
>UniRef50_P41511 Cluster: DNA topoisomerase 1; n=1; Ustilago
maydis|Rep: DNA topoisomerase 1 - Ustilago maydis (Smut
fungus)
Length = 1019
Score = 100 bits (239), Expect = 2e-20
Identities = 42/90 (46%), Positives = 58/90 (64%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
+ ++ C +DG ++++GN +EPPGLF GRG HPK GK+KRR+ P D+ IN S D P+
Sbjct: 288 ETKWKICLVDGVEQRVGNVNVEPPGLFLGRGAHPKAGKVKRRISPGDITINHSADHPAPQ 347
Query: 181 PPSG-HKWREVRHDNTVTWLASWTEKFSSK 267
PP+G W EV VTWLA W E + +
Sbjct: 348 PPAGMGDWAEVVEKKDVTWLAYWKENINGQ 377
Score = 54.4 bits (125), Expect = 1e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+ Q KYV L+ +S K D +K+E ARKL + +IR + + K+K Q A +
Sbjct: 374 INGQYKYVFLDATSNFKTNSDREKFEKARKLDTVVKQIRRDVNKNLKSKVRHERQIATIV 433
Query: 435 YFIDRLALTAXNEKDDEQ 488
+ ID +L A NEK +++
Sbjct: 434 WLIDNFSLRAGNEKGEDE 451
>UniRef50_Q4N5U3 Cluster: DNA topoisomerase I, putative; n=2;
Theileria|Rep: DNA topoisomerase I, putative - Theileria
parva
Length = 1003
Score = 98.7 bits (235), Expect = 6e-20
Identities = 39/90 (43%), Positives = 63/90 (70%), Gaps = 4/90 (4%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKPPS 189
+ + +D +EK+ + ++EPPGLF+GRG HPK G LK R+ P+DV++N SKD+ +PK +
Sbjct: 455 FNYALVDWVREKVSSNKLEPPGLFKGRGLHPKQGLLKARMFPKDVILNLSKDAPVPKVSN 514
Query: 190 ----GHKWREVRHDNTVTWLASWTEKFSSK 267
GH W+++ HDN+VTWLA + + + +
Sbjct: 515 FQREGHSWKDIYHDNSVTWLAYYKDSINDQ 544
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/78 (37%), Positives = 42/78 (53%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+ Q KY+ L+ SK KG D+ KY AR+L I KIR++ + ++ Q A+
Sbjct: 541 INDQFKYMYLSAQSKFKGFHDFLKYNKARELKAYIQKIRDDYNTKMLSMDIYEKQLGTAV 600
Query: 435 YFIDRLALTAXNEKDDEQ 488
Y ID LAL EKD ++
Sbjct: 601 YLIDFLALRVGGEKDADE 618
>UniRef50_A7AUT4 Cluster: DNA topoisomerase; n=1; Babesia bovis|Rep:
DNA topoisomerase - Babesia bovis
Length = 701
Score = 93.9 bits (223), Expect = 2e-18
Identities = 42/90 (46%), Positives = 61/90 (67%), Gaps = 6/90 (6%)
Frame = +1
Query: 1 QKEYGFC--TIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKI 174
+KE+ +C +D +EK+G+ R+EPPGLF+GRG HPK G LK R P V++N SKD+ +
Sbjct: 231 KKEHPYCYALVDWIREKVGSNRMEPPGLFKGRGLHPKQGLLKGRTFPHSVVLNLSKDAPV 290
Query: 175 PK----PPSGHKWREVRHDNTVTWLASWTE 252
PK GH W ++ HD++VTWLA + +
Sbjct: 291 PKVSMFERQGHGWSDIFHDSSVTWLAYYRD 320
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/78 (39%), Positives = 41/78 (52%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
V Q KY+ SK KG D+ KY AR+L K I KIR++ ++ E+ Q A
Sbjct: 322 VNDQTKYMYPAAQSKFKGLHDFLKYSKARELKKHIMKIRKDYHGKMRSPEIVDRQLGTAT 381
Query: 435 YFIDRLALTAXNEKDDEQ 488
Y ID LAL EKD ++
Sbjct: 382 YLIDFLALRVGGEKDADE 399
>UniRef50_A0CF77 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 725
Score = 91.9 bits (218), Expect = 7e-18
Identities = 37/82 (45%), Positives = 55/82 (67%), Gaps = 1/82 (1%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK-PP 186
YG+ +DG E++GN+ +E P LF+GRGEHPK G LK R+ PE++ +N S + +P+
Sbjct: 158 YGYALVDGCLERVGNYTLEQPTLFKGRGEHPKAGLLKARIFPEELTVNLSTQAPVPQCKL 217
Query: 187 SGHKWREVRHDNTVTWLASWTE 252
GH W ++ H N VTWL S+ +
Sbjct: 218 PGHSWGKIVHRNDVTWLFSYVD 239
Score = 61.3 bits (142), Expect = 1e-08
Identities = 31/89 (34%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = +3
Query: 225 SYMVSLLDREVQQQA-KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAK 401
+++ S +D +++ KYV +S+ K D +KYE AR+L ID+IREN ++
Sbjct: 232 TWLFSYVDSSIRKDNHKYVQFAATSRFKQMNDKRKYEKARRLKNQIDQIRENYTKKLQSD 291
Query: 402 EMQVXQRAVALYFIDRLALTAXNEKDDEQ 488
++ Q A Y ID+LAL N+KD+++
Sbjct: 292 SIKERQLGTATYLIDKLALRVGNDKDEDE 320
>UniRef50_Q24BB2 Cluster: Eukaryotic DNA topoisomerase I, catalytic
core family protein; n=1; Tetrahymena thermophila
SB210|Rep: Eukaryotic DNA topoisomerase I, catalytic
core family protein - Tetrahymena thermophila SB210
Length = 713
Score = 89.4 bits (212), Expect = 4e-17
Identities = 46/100 (46%), Positives = 58/100 (58%), Gaps = 19/100 (19%)
Frame = +1
Query: 10 YGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK--- 180
Y +DG +EK+G F IEPP LF+GRGEHPKMG +K R+ PE V+IN SKD+ +PK
Sbjct: 253 YAGAILDGFREKVGQFMIEPPTLFKGRGEHPKMGMMKGRIQPEAVVINISKDAPVPKCSV 312
Query: 181 --------------PPS--GHKWREVRHDNTVTWLASWTE 252
P GH W E+ H VTWLAS+ +
Sbjct: 313 PDCIHICRQIFNEFPKKQLGHGWSEIVHKQDVTWLASYKD 352
Score = 72.5 bits (170), Expect = 5e-12
Identities = 36/88 (40%), Positives = 52/88 (59%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++ S D V++Q KY+ L+ SKLK E D +KYE AR+L I +IREN ++ +
Sbjct: 345 TWLASYKDDSVKKQHKYIFLSAESKLKAENDKKKYEKARRLKNLIGQIRENYERKLRSSD 404
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDDEQ 488
Q A Y ID+LAL NEK +E+
Sbjct: 405 PVDRQLGTATYLIDKLALRVGNEKSEEE 432
>UniRef50_A7DNZ3 Cluster: 2-alkenal reductase; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: 2-alkenal reductase -
Candidatus Nitrosopumilus maritimus SCM1
Length = 551
Score = 88.2 bits (209), Expect = 9e-17
Identities = 44/126 (34%), Positives = 71/126 (56%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
+ +YG +DG + ++GN+ EPPG+F GRGEHP G+ K RV +DV +N K++K+P+
Sbjct: 121 KSKYGVAVMDGKEVEVGNYMAEPPGIFIGRGEHPLRGRWKPRVTAKDVTLNLGKEAKVPE 180
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKLSMSC*IPVQN*RVKKIGRNMRLLENFISV* 360
KW ++ HD WLASW + + K + + + K GR+ E + +
Sbjct: 181 ----GKWGKIIHDKDSMWLASWMDFLTQKRKY---VWLSDSSDLKQGRDKEKYEKAVKLE 233
Query: 361 TKLEKI 378
++EKI
Sbjct: 234 KEIEKI 239
Score = 51.2 bits (117), Expect = 1e-05
Identities = 30/76 (39%), Positives = 45/76 (59%)
Frame = +3
Query: 261 QQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYF 440
Q+ KYV L+ SS LK +D +KYE A KL K I+KI++ D K+ + A A Y
Sbjct: 204 QKRKYVWLSDSSDLKQGRDKEKYEKAVKLEKEIEKIKKAMVKD--MKDSKKNNVATACYL 261
Query: 441 IDRLALTAXNEKDDEQ 488
I + A+ +EKD+++
Sbjct: 262 IYKTAMRVGDEKDEDE 277
>UniRef50_A0RU10 Cluster: DNA topoisomerase IB; n=1; Cenarchaeum
symbiosum|Rep: DNA topoisomerase IB - Cenarchaeum
symbiosum
Length = 519
Score = 83.0 bits (196), Expect = 3e-15
Identities = 35/87 (40%), Positives = 54/87 (62%)
Frame = +1
Query: 7 EYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKPP 186
+YG +DG + +I ++ EPPG+F GRG+HP GK KRR+ P+DV++N +K PP
Sbjct: 120 KYGIAVMDGKEVEIASYMAEPPGIFIGRGKHPLRGKWKRRIGPQDVVLNMG--TKAKAPP 177
Query: 187 SGHKWREVRHDNTVTWLASWTEKFSSK 267
KW+++ H+ W+A WT+ K
Sbjct: 178 G--KWKKIVHEKDGIWIAKWTDNLVKK 202
Score = 50.8 bits (116), Expect = 2e-05
Identities = 28/73 (38%), Positives = 41/73 (56%)
Frame = +3
Query: 270 KYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVALYFIDR 449
KYV L ++ LK E+D KYE A L K I +I D K+K+ ++ + A A Y I R
Sbjct: 204 KYVWLADTAGLKQERDRSKYEKAVALSKKIGEIEAKIVKDMKSKDPKISKIATACYLIYR 263
Query: 450 LALTAXNEKDDEQ 488
A+ +EKD ++
Sbjct: 264 TAMRVGDEKDKDE 276
>UniRef50_P93119 Cluster: DNA topoisomerase 1; n=1; Daucus
carota|Rep: DNA topoisomerase 1 - Daucus carota (Carrot)
Length = 790
Score = 78.6 bits (185), Expect = 7e-14
Identities = 36/92 (39%), Positives = 58/92 (63%), Gaps = 3/92 (3%)
Frame = +1
Query: 1 QKEYGFCTIDG-HKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPE-DVLINCSKDSKI 174
+++Y + +DG +EK+GNFR+ + + K ++K+ V + D+ IN KD+ I
Sbjct: 332 KEKYMWAVVDGMSREKVGNFRVGTTRVVQRSWRASKDPQVKKNVYSQIDITINIGKDAPI 391
Query: 175 PKPP-SGHKWREVRHDNTVTWLASWTEKFSSK 267
P+PP G +W+E+RHDNTVTWLA W + + K
Sbjct: 392 PEPPIPGERWKEIRHDNTVTWLAFWNDPINPK 423
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/146 (36%), Positives = 75/146 (51%), Gaps = 5/146 (3%)
Frame = +3
Query: 66 TPRVV*RSGRAPKNGEIKETCYA*RCLNQLLXXXXXXXXXXXX*MERSKT**YSYMVSLL 245
T RVV RS RA K+ ++K+ Y+ + + ER K + V+ L
Sbjct: 355 TTRVVQRSWRASKDPQVKKNVYSQIDITINIGKDAPIPEPPIP-GERWKEIRHDNTVTWL 413
Query: 246 ----DREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRA-DWKAKEMQ 410
D ++ KYV L SS LKG+ +KYE +RKL I+ IR D+ +K+ +
Sbjct: 414 AFWNDPINPKEFKYVFLAASSSLKGKVTREKYEKSRKLKDYIEGIRAAAYTKDFASKDSK 473
Query: 411 VXQRAVALYFIDRLALTAXNEKDDEQ 488
Q AVA Y ID+LAL A NEKDD++
Sbjct: 474 KRQIAVATYLIDKLALRAGNEKDDDE 499
>UniRef50_O58143 Cluster: Putative uncharacterized protein PH0406;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH0406 - Pyrococcus horikoshii
Length = 147
Score = 34.7 bits (76), Expect = 1.2
Identities = 20/47 (42%), Positives = 28/47 (59%)
Frame = +1
Query: 94 EHPKMGKLKRRVMPEDVLINCSKDSKIPKPPSGHKWREVRHDNTVTW 234
E P++GK K RV E V+ SK+++I K P+G W VR +TW
Sbjct: 99 EDPELGKYKIRVEIEPVM--ASKNTQI-KTPNGEPWYVVRWVPKITW 142
>UniRef50_Q8FP72 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium efficiens|Rep: Putative uncharacterized
protein - Corynebacterium efficiens
Length = 60
Score = 31.9 bits (69), Expect = 8.2
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +1
Query: 85 GRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKPPSGHKWREV-RHDNTVTWLASWT 249
GRGEHP G D+ + C +S PP+G R++ H T+ AS T
Sbjct: 4 GRGEHPFPGSTPHSAPHIDISLMCGAESCAQSPPAGGYRRDILTHVRTLPAGASVT 59
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 440,164,018
Number of Sequences: 1657284
Number of extensions: 7942942
Number of successful extensions: 20191
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 19655
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 20170
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 29273652170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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