Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= msgV0641.Seq
(499 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC071914-1|AAH71914.1| 601|Homo sapiens topoisomerase (DNA) I, ... 166 4e-41
BC052285-1|AAH52285.1| 601|Homo sapiens topoisomerase (DNA) I, ... 166 4e-41
BC044646-1|AAH44646.1| 602|Homo sapiens TOP1MT protein protein. 166 4e-41
U07804-1|AAB60379.1| 761|Homo sapiens DNA topoisomerase I protein. 165 6e-41
M60706-1|AAA61206.1| 765|Homo sapiens topoisomerase I protein. 165 6e-41
J03250-1|AAA61207.1| 765|Homo sapiens TOP1 protein. 165 6e-41
AL035652-1|CAI19767.1| 765|Homo sapiens topoisomerase (DNA) I p... 165 6e-41
AL022394-1|CAI42886.1| 765|Homo sapiens topoisomerase (DNA) I p... 165 6e-41
AF349031-1|AAL10791.1| 601|Homo sapiens topoisomerase I protein. 165 6e-41
AF349017-1|AAL05624.1| 601|Homo sapiens topoisomerase I protein. 165 6e-41
U07806-1|AAB60380.1| 761|Homo sapiens DNA topoisomerase I protein. 163 3e-40
>BC071914-1|AAH71914.1| 601|Homo sapiens topoisomerase (DNA) I,
mitochondrial protein.
Length = 601
Score = 166 bits (403), Expect = 4e-41
Identities = 65/90 (72%), Positives = 82/90 (91%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G+C +DGH+EKIGNF+IEPPGLFRGRG+HPKMG LKRR+ PEDV+INCS+DSKIP+
Sbjct: 171 QQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPE 230
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP+GH+W+EVR DNTVTWLA+WTE + +
Sbjct: 231 PPAGHQWKEVRSDNTVTWLAAWTESIQNSI 260
Score = 110 bits (265), Expect = 2e-24
Identities = 49/76 (64%), Positives = 60/76 (78%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+Q KY+MLNP SKLKGE WQK+ETAR+L +D+IR RADWK++EM+ QRAVAL
Sbjct: 256 IQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVAL 315
Query: 435 YFIDRLALTAXNEKDD 482
YFID+LAL A NEK+D
Sbjct: 316 YFIDKLALRAGNEKED 331
>BC052285-1|AAH52285.1| 601|Homo sapiens topoisomerase (DNA) I,
mitochondrial protein.
Length = 601
Score = 166 bits (403), Expect = 4e-41
Identities = 65/90 (72%), Positives = 82/90 (91%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G+C +DGH+EKIGNF+IEPPGLFRGRG+HPKMG LKRR+ PEDV+INCS+DSKIP+
Sbjct: 171 QQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPE 230
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP+GH+W+EVR DNTVTWLA+WTE + +
Sbjct: 231 PPAGHQWKEVRSDNTVTWLAAWTESIQNSI 260
Score = 110 bits (265), Expect = 2e-24
Identities = 49/76 (64%), Positives = 60/76 (78%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+Q KY+MLNP SKLKGE WQK+ETAR+L +D+IR RADWK++EM+ QRAVAL
Sbjct: 256 IQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVAL 315
Query: 435 YFIDRLALTAXNEKDD 482
YFID+LAL A NEK+D
Sbjct: 316 YFIDKLALRAGNEKED 331
>BC044646-1|AAH44646.1| 602|Homo sapiens TOP1MT protein protein.
Length = 602
Score = 166 bits (403), Expect = 4e-41
Identities = 65/90 (72%), Positives = 82/90 (91%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G+C +DGH+EKIGNF+IEPPGLFRGRG+HPKMG LKRR+ PEDV+INCS+DSKIP+
Sbjct: 172 QQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPE 231
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP+GH+W+EVR DNTVTWLA+WTE + +
Sbjct: 232 PPAGHQWKEVRSDNTVTWLAAWTESIQNSI 261
Score = 110 bits (265), Expect = 2e-24
Identities = 49/76 (64%), Positives = 60/76 (78%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
+Q KY+MLNP SKLKGE WQK+ETAR+L +D+IR RADWK++EM+ QRAVAL
Sbjct: 257 IQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVAL 316
Query: 435 YFIDRLALTAXNEKDD 482
YFID+LAL A NEK+D
Sbjct: 317 YFIDKLALRAGNEKED 332
>U07804-1|AAB60379.1| 761|Homo sapiens DNA topoisomerase I protein.
Length = 761
Score = 165 bits (402), Expect = 6e-41
Identities = 65/89 (73%), Positives = 75/89 (84%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPKMG LKRR+MPED++INCSKD+K+P P
Sbjct: 332 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 391
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 392 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 420
Score = 125 bits (301), Expect = 1e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 407 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 465
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 466 MKVRQRAVALYFIDKLALRAGNEKEE 491
>M60706-1|AAA61206.1| 765|Homo sapiens topoisomerase I protein.
Length = 765
Score = 165 bits (402), Expect = 6e-41
Identities = 65/89 (73%), Positives = 75/89 (84%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPKMG LKRR+MPED++INCSKD+K+P P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 395
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 396 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 424
Score = 125 bits (301), Expect = 1e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 411 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 469
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 470 MKVRQRAVALYFIDKLALRAGNEKEE 495
>J03250-1|AAA61207.1| 765|Homo sapiens TOP1 protein.
Length = 765
Score = 165 bits (402), Expect = 6e-41
Identities = 65/89 (73%), Positives = 75/89 (84%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPKMG LKRR+MPED++INCSKD+K+P P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 395
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 396 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 424
Score = 125 bits (301), Expect = 1e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 411 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 469
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 470 MKVRQRAVALYFIDKLALRAGNEKEE 495
>AL035652-1|CAI19767.1| 765|Homo sapiens topoisomerase (DNA) I
protein.
Length = 765
Score = 165 bits (402), Expect = 6e-41
Identities = 65/89 (73%), Positives = 75/89 (84%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPKMG LKRR+MPED++INCSKD+K+P P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 395
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 396 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 424
Score = 125 bits (301), Expect = 1e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 411 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 469
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 470 MKVRQRAVALYFIDKLALRAGNEKEE 495
>AL022394-1|CAI42886.1| 765|Homo sapiens topoisomerase (DNA) I
protein.
Length = 765
Score = 165 bits (402), Expect = 6e-41
Identities = 65/89 (73%), Positives = 75/89 (84%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPKMG LKRR+MPED++INCSKD+K+P P
Sbjct: 336 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSP 395
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 396 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 424
Score = 125 bits (301), Expect = 1e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 411 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 469
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 470 MKVRQRAVALYFIDKLALRAGNEKEE 495
>AF349031-1|AAL10791.1| 601|Homo sapiens topoisomerase I protein.
Length = 601
Score = 165 bits (402), Expect = 6e-41
Identities = 65/90 (72%), Positives = 82/90 (91%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G+C +DGH+EKIGNF+IEPPGLFRGRG+HPKMG LKRR+ PEDV+INCS+DSKIP+
Sbjct: 171 QQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPE 230
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP+GH+W+EVR DNTVTWLA+WTE + +
Sbjct: 231 PPAGHQWKEVRSDNTVTWLAAWTESVQNSI 260
Score = 111 bits (266), Expect = 2e-24
Identities = 50/76 (65%), Positives = 60/76 (78%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
VQ KY+MLNP SKLKGE WQK+ETAR+L +D+IR RADWK++EM+ QRAVAL
Sbjct: 256 VQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVAL 315
Query: 435 YFIDRLALTAXNEKDD 482
YFID+LAL A NEK+D
Sbjct: 316 YFIDKLALRAGNEKED 331
>AF349017-1|AAL05624.1| 601|Homo sapiens topoisomerase I protein.
Length = 601
Score = 165 bits (402), Expect = 6e-41
Identities = 65/90 (72%), Positives = 82/90 (91%)
Frame = +1
Query: 1 QKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPK 180
Q+E+G+C +DGH+EKIGNF+IEPPGLFRGRG+HPKMG LKRR+ PEDV+INCS+DSKIP+
Sbjct: 171 QQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPE 230
Query: 181 PPSGHKWREVRHDNTVTWLASWTEKFSSKL 270
PP+GH+W+EVR DNTVTWLA+WTE + +
Sbjct: 231 PPAGHQWKEVRSDNTVTWLAAWTESVQNSI 260
Score = 111 bits (266), Expect = 2e-24
Identities = 50/76 (65%), Positives = 60/76 (78%)
Frame = +3
Query: 255 VQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKEMQVXQRAVAL 434
VQ KY+MLNP SKLKGE WQK+ETAR+L +D+IR RADWK++EM+ QRAVAL
Sbjct: 256 VQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVAL 315
Query: 435 YFIDRLALTAXNEKDD 482
YFID+LAL A NEK+D
Sbjct: 316 YFIDKLALRAGNEKED 331
>U07806-1|AAB60380.1| 761|Homo sapiens DNA topoisomerase I protein.
Length = 761
Score = 163 bits (396), Expect = 3e-40
Identities = 64/89 (71%), Positives = 74/89 (83%)
Frame = +1
Query: 4 KEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGKLKRRVMPEDVLINCSKDSKIPKP 183
KEYGFC +D HKE+I NF+IEPPGLFRGRG HPK G LKRR+MPED++INCSKD+K+P P
Sbjct: 332 KEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKTGMLKRRIMPEDIIINCSKDAKVPSP 391
Query: 184 PSGHKWREVRHDNTVTWLASWTEKFSSKL 270
P GHKW+EVRHDN VTWL SWTE +
Sbjct: 392 PPGHKWKEVRHDNKVTWLVSWTENIQGSI 420
Score = 125 bits (301), Expect = 1e-28
Identities = 56/86 (65%), Positives = 71/86 (82%)
Frame = +3
Query: 225 SYMVSLLDREVQQQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRENXRADWKAKE 404
+++VS + +Q KY+MLNPSS++KGEKDWQKYETAR+L KC+DKIR R DWK+KE
Sbjct: 407 TWLVSWTEN-IQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKE 465
Query: 405 MQVXQRAVALYFIDRLALTAXNEKDD 482
M+V QRAVALYFID+LAL A NEK++
Sbjct: 466 MKVRQRAVALYFIDKLALRAGNEKEE 491
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 64,793,867
Number of Sequences: 237096
Number of extensions: 1237859
Number of successful extensions: 6314
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6204
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6314
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4536472160
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -