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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= msgV0518.Seq
         (598 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Z11692-1|CAA77750.1|  858|Homo sapiens human  elongation factor ...   163   3e-40
X51466-1|CAA35829.1|  858|Homo sapiens elongation factor 2 protein.   163   3e-40
M19997-1|AAA50388.1|  358|Homo sapiens elongation factor 2 protein.   163   3e-40
BC126259-1|AAI26260.1|  858|Homo sapiens EEF2 protein protein.        163   3e-40
BC024689-1|AAH24689.1|  517|Homo sapiens Similar to Elongation f...   163   3e-40
AY942181-1|AAX34409.1|  858|Homo sapiens elongation factor 2 pro...   163   3e-40
D21163-1|BAA04699.2|  977|Homo sapiens KIAA0031 protein.               95   2e-19
CR456774-1|CAG33055.1|  972|Homo sapiens U5-116KD protein.             95   2e-19
BC002360-1|AAH02360.1|  972|Homo sapiens elongation factor Tu GT...    95   2e-19
AJ505017-1|CAD43720.1|  850|Homo sapiens small nuclear ribonucle...    95   2e-19
AK023181-1|BAB14450.1|  857|Homo sapiens protein ( Homo sapiens ...    82   2e-15
BC049210-1|AAH49210.1|  751|Homo sapiens G elongation factor, mi...    43   0.001
AF367998-1|AAK53402.1|  751|Homo sapiens elongation factor G1 pr...    43   0.001
AF309777-1|AAK58877.1|  751|Homo sapiens elongation factor G pro...    43   0.001
AY093673-1|AAM44451.1|  169|Homo sapiens p53-activated protein-2...    36   0.14 

>Z11692-1|CAA77750.1|  858|Homo sapiens human  elongation factor 2
           protein.
          Length = 858

 Score =  163 bits (397), Expect = 3e-40
 Identities = 73/85 (85%), Positives = 77/85 (90%)
 Frame = -1

Query: 508 QPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGF 329
           QPRLMEP+YL EIQCPE  VGGI GVLNR+RGHVFEESQVAGTPMF+VKA LP NESFGF
Sbjct: 737 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 796

Query: 328 TADLRSNTGGQAFPQCVFDHXQVXP 254
           TADLRSNTGGQAFPQCVFDH Q+ P
Sbjct: 797 TADLRSNTGGQAFPQCVFDHWQILP 821



 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 23/27 (85%), Positives = 24/27 (88%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASP 502
           DAIHRGGGQIIPT RRCLYA +LTA P
Sbjct: 712 DAIHRGGGQIIPTARRCLYASVLTAQP 738



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 19/29 (65%), Positives = 22/29 (75%)
 Frame = -3

Query: 257 PGDPCEPQSKPXNVXQETRKRKGLKEGLP 171
           PGDP +  S+P  V  ETRKRKGLKEG+P
Sbjct: 821 PGDPFDNSSRPSQVVAETRKRKGLKEGIP 849


>X51466-1|CAA35829.1|  858|Homo sapiens elongation factor 2 protein.
          Length = 858

 Score =  163 bits (397), Expect = 3e-40
 Identities = 73/85 (85%), Positives = 77/85 (90%)
 Frame = -1

Query: 508 QPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGF 329
           QPRLMEP+YL EIQCPE  VGGI GVLNR+RGHVFEESQVAGTPMF+VKA LP NESFGF
Sbjct: 737 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 796

Query: 328 TADLRSNTGGQAFPQCVFDHXQVXP 254
           TADLRSNTGGQAFPQCVFDH Q+ P
Sbjct: 797 TADLRSNTGGQAFPQCVFDHWQILP 821



 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 23/27 (85%), Positives = 24/27 (88%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASP 502
           DAIHRGGGQIIPT RRCLYA +LTA P
Sbjct: 712 DAIHRGGGQIIPTARRCLYASVLTAQP 738



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 19/29 (65%), Positives = 22/29 (75%)
 Frame = -3

Query: 257 PGDPCEPQSKPXNVXQETRKRKGLKEGLP 171
           PGDP +  S+P  V  ETRKRKGLKEG+P
Sbjct: 821 PGDPFDNSSRPSQVVAETRKRKGLKEGIP 849


>M19997-1|AAA50388.1|  358|Homo sapiens elongation factor 2 protein.
          Length = 358

 Score =  163 bits (397), Expect = 3e-40
 Identities = 73/85 (85%), Positives = 77/85 (90%)
 Frame = -1

Query: 508 QPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGF 329
           QPRLMEP+YL EIQCPE  VGGI GVLNR+RGHVFEESQVAGTPMF+VKA LP NESFGF
Sbjct: 237 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 296

Query: 328 TADLRSNTGGQAFPQCVFDHXQVXP 254
           TADLRSNTGGQAFPQCVFDH Q+ P
Sbjct: 297 TADLRSNTGGQAFPQCVFDHWQILP 321



 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 23/27 (85%), Positives = 24/27 (88%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASP 502
           DAIHRGGGQIIPT RRCLYA +LTA P
Sbjct: 212 DAIHRGGGQIIPTARRCLYASVLTAQP 238



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 19/29 (65%), Positives = 22/29 (75%)
 Frame = -3

Query: 257 PGDPCEPQSKPXNVXQETRKRKGLKEGLP 171
           PGDP +  S+P  V  ETRKRKGLKEG+P
Sbjct: 321 PGDPFDNSSRPSQVVAETRKRKGLKEGIP 349


>BC126259-1|AAI26260.1|  858|Homo sapiens EEF2 protein protein.
          Length = 858

 Score =  163 bits (397), Expect = 3e-40
 Identities = 73/85 (85%), Positives = 77/85 (90%)
 Frame = -1

Query: 508 QPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGF 329
           QPRLMEP+YL EIQCPE  VGGI GVLNR+RGHVFEESQVAGTPMF+VKA LP NESFGF
Sbjct: 737 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 796

Query: 328 TADLRSNTGGQAFPQCVFDHXQVXP 254
           TADLRSNTGGQAFPQCVFDH Q+ P
Sbjct: 797 TADLRSNTGGQAFPQCVFDHWQILP 821



 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 23/27 (85%), Positives = 24/27 (88%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASP 502
           DAIHRGGGQIIPT RRCLYA +LTA P
Sbjct: 712 DAIHRGGGQIIPTARRCLYASVLTAQP 738



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 19/29 (65%), Positives = 22/29 (75%)
 Frame = -3

Query: 257 PGDPCEPQSKPXNVXQETRKRKGLKEGLP 171
           PGDP +  S+P  V  ETRKRKGLKEG+P
Sbjct: 821 PGDPFDNSSRPSQVVAETRKRKGLKEGIP 849


>BC024689-1|AAH24689.1|  517|Homo sapiens Similar to Elongation
           factor 2b protein.
          Length = 517

 Score =  163 bits (397), Expect = 3e-40
 Identities = 73/85 (85%), Positives = 77/85 (90%)
 Frame = -1

Query: 508 QPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGF 329
           QPRLMEP+YL EIQCPE  VGGI GVLNR+RGHVFEESQVAGTPMF+VKA LP NESFGF
Sbjct: 396 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 455

Query: 328 TADLRSNTGGQAFPQCVFDHXQVXP 254
           TADLRSNTGGQAFPQCVFDH Q+ P
Sbjct: 456 TADLRSNTGGQAFPQCVFDHWQILP 480



 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 23/27 (85%), Positives = 24/27 (88%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASP 502
           DAIHRGGGQIIPT RRCLYA +LTA P
Sbjct: 371 DAIHRGGGQIIPTARRCLYASVLTAQP 397



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 19/29 (65%), Positives = 22/29 (75%)
 Frame = -3

Query: 257 PGDPCEPQSKPXNVXQETRKRKGLKEGLP 171
           PGDP +  S+P  V  ETRKRKGLKEG+P
Sbjct: 480 PGDPFDNSSRPSQVVAETRKRKGLKEGIP 508


>AY942181-1|AAX34409.1|  858|Homo sapiens elongation factor 2
           protein.
          Length = 858

 Score =  163 bits (397), Expect = 3e-40
 Identities = 73/85 (85%), Positives = 77/85 (90%)
 Frame = -1

Query: 508 QPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGF 329
           QPRLMEP+YL EIQCPE  VGGI GVLNR+RGHVFEESQVAGTPMF+VKA LP NESFGF
Sbjct: 737 QPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGF 796

Query: 328 TADLRSNTGGQAFPQCVFDHXQVXP 254
           TADLRSNTGGQAFPQCVFDH Q+ P
Sbjct: 797 TADLRSNTGGQAFPQCVFDHWQILP 821



 Score = 53.6 bits (123), Expect = 5e-07
 Identities = 23/27 (85%), Positives = 24/27 (88%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASP 502
           DAIHRGGGQIIPT RRCLYA +LTA P
Sbjct: 712 DAIHRGGGQIIPTARRCLYASVLTAQP 738



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 19/29 (65%), Positives = 22/29 (75%)
 Frame = -3

Query: 257 PGDPCEPQSKPXNVXQETRKRKGLKEGLP 171
           PGDP +  S+P  V  ETRKRKGLKEG+P
Sbjct: 821 PGDPFDNSSRPSQVVAETRKRKGLKEGIP 849


>D21163-1|BAA04699.2|  977|Homo sapiens KIAA0031 protein.
          Length = 977

 Score = 94.7 bits (225), Expect = 2e-19
 Identities = 41/84 (48%), Positives = 56/84 (66%)
 Frame = -1

Query: 505  PRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGFT 326
            PRLMEP Y  E+Q P   V  +  VL RRRGHV +++ + G+P++ +KA +P  +SFGF 
Sbjct: 830  PRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFE 889

Query: 325  ADLRSNTGGQAFPQCVFDHXQVXP 254
             DLR++T GQAF   VF H Q+ P
Sbjct: 890  TDLRTHTQGQAFSLSVFHHWQIVP 913



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 19/37 (51%), Positives = 25/37 (67%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASPVSWSLYIFVK 472
           + +HRGGGQIIPT RR +Y+  L A+P     Y FV+
Sbjct: 804 EPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVE 840


>CR456774-1|CAG33055.1|  972|Homo sapiens U5-116KD protein.
          Length = 972

 Score = 94.7 bits (225), Expect = 2e-19
 Identities = 41/84 (48%), Positives = 56/84 (66%)
 Frame = -1

Query: 505  PRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGFT 326
            PRLMEP Y  E+Q P   V  +  VL RRRGHV +++ + G+P++ +KA +P  +SFGF 
Sbjct: 825  PRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFE 884

Query: 325  ADLRSNTGGQAFPQCVFDHXQVXP 254
             DLR++T GQAF   VF H Q+ P
Sbjct: 885  TDLRTHTQGQAFSLSVFHHWQIVP 908



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 19/37 (51%), Positives = 25/37 (67%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASPVSWSLYIFVK 472
           + +HRGGGQIIPT RR +Y+  L A+P     Y FV+
Sbjct: 799 EPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVE 835


>BC002360-1|AAH02360.1|  972|Homo sapiens elongation factor Tu GTP
            binding domain containing 2 protein.
          Length = 972

 Score = 94.7 bits (225), Expect = 2e-19
 Identities = 41/84 (48%), Positives = 56/84 (66%)
 Frame = -1

Query: 505  PRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGFT 326
            PRLMEP Y  E+Q P   V  +  VL RRRGHV +++ + G+P++ +KA +P  +SFGF 
Sbjct: 825  PRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFE 884

Query: 325  ADLRSNTGGQAFPQCVFDHXQVXP 254
             DLR++T GQAF   VF H Q+ P
Sbjct: 885  TDLRTHTQGQAFSLSVFHHWQIVP 908



 Score = 44.0 bits (99), Expect = 4e-04
 Identities = 19/37 (51%), Positives = 25/37 (67%)
 Frame = -2

Query: 582 DAIHRGGGQIIPTXRRCLYACLLTASPVSWSLYIFVK 472
           + +HRGGGQIIPT RR +Y+  L A+P     Y FV+
Sbjct: 799 EPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVE 835


>AJ505017-1|CAD43720.1|  850|Homo sapiens small nuclear
           ribonucleoprotein component protein.
          Length = 850

 Score = 94.7 bits (225), Expect = 2e-19
 Identities = 41/84 (48%), Positives = 56/84 (66%)
 Frame = -1

Query: 505 PRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGFT 326
           PRLMEP Y  E+Q P   V  +  VL RRRGHV +++ + G+P++ +KA +P  +SFGF 
Sbjct: 703 PRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFE 762

Query: 325 ADLRSNTGGQAFPQCVFDHXQVXP 254
            DLR++T GQAF   VF H Q+ P
Sbjct: 763 TDLRTHTQGQAFSLSVFHHWQIVP 786



 Score = 43.6 bits (98), Expect = 5e-04
 Identities = 19/35 (54%), Positives = 24/35 (68%)
 Frame = -2

Query: 576 IHRGGGQIIPTXRRCLYACLLTASPVSWSLYIFVK 472
           +HRGGGQIIPT RR +Y+  L A+P     Y FV+
Sbjct: 679 LHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVE 713


>AK023181-1|BAB14450.1|  857|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13119 fis, clone NT2RP3002671, weakly similar to
           ELONGATION FACTOR 2. ).
          Length = 857

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 37/83 (44%), Positives = 49/83 (59%)
 Frame = -1

Query: 502 RLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNESFGFTA 323
           RLM  +Y C+I      +G +  VL++R G V +E    GT MFI+KA LP  ESFGF  
Sbjct: 716 RLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFAD 775

Query: 322 DLRSNTGGQAFPQCVFDHXQVXP 254
           ++R  T G A PQ VF H ++ P
Sbjct: 776 EIRKRTSGLASPQLVFSHWEIIP 798


>BC049210-1|AAH49210.1|  751|Homo sapiens G elongation factor,
           mitochondrial 1 protein.
          Length = 751

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = -1

Query: 517 ANCQPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNES 338
           AN    ++EP+   E+  P    G +   +NRR G +  +  V     F + A +P N+ 
Sbjct: 639 ANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVED--YFTLYADVPLNDM 696

Query: 337 FGFTADLRSNTGGQ 296
           FG++ +LRS T G+
Sbjct: 697 FGYSTELRSCTEGK 710


>AF367998-1|AAK53402.1|  751|Homo sapiens elongation factor G1
           protein.
          Length = 751

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = -1

Query: 517 ANCQPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNES 338
           AN    ++EP+   E+  P    G +   +NRR G +  +  V     F + A +P N+ 
Sbjct: 639 ANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVED--YFTLYADVPLNDM 696

Query: 337 FGFTADLRSNTGGQ 296
           FG++ +LRS T G+
Sbjct: 697 FGYSTELRSCTEGK 710


>AF309777-1|AAK58877.1|  751|Homo sapiens elongation factor G
           protein.
          Length = 751

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = -1

Query: 517 ANCQPRLMEPVYLCEIQCPEVAVGGIXGVLNRRRGHVFEESQVAGTPMFIVKAXLPXNES 338
           AN    ++EP+   E+  P    G +   +NRR G +  +  V     F + A +P N+ 
Sbjct: 639 ANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVED--YFTLYADVPLNDM 696

Query: 337 FGFTADLRSNTGGQ 296
           FG++ +LRS T G+
Sbjct: 697 FGYSTELRSCTEGK 710


>AY093673-1|AAM44451.1|  169|Homo sapiens p53-activated protein-2
           protein.
          Length = 169

 Score = 35.5 bits (78), Expect = 0.14
 Identities = 18/43 (41%), Positives = 23/43 (53%)
 Frame = -3

Query: 323 RFAFQHRRTGLPAVRIRPXAGPPGDPCEPQSKPXNVXQETRKR 195
           R   Q R+TG    R++P A PPG P  P   P N  ++TR R
Sbjct: 65  RLRSQPRQTGRQPPRVQPLAPPPGAPA-PLPNPQNCRRKTRSR 106


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,292,872
Number of Sequences: 237096
Number of extensions: 1691979
Number of successful extensions: 3491
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3278
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3488
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6324506272
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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