Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= msgV0465.Seq
(449 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F5L1 Cluster: Signal peptidase 18 kDa subunit; n=5; C... 148 6e-35
UniRef50_Q9BY50 Cluster: Signal peptidase complex catalytic subu... 120 1e-26
UniRef50_Q0DJD8 Cluster: Os05g0297900 protein; n=7; Oryza sativa... 93 3e-18
UniRef50_Q9SSR2 Cluster: F6D8.18 protein; n=17; Magnoliophyta|Re... 89 4e-17
UniRef50_A5APG1 Cluster: Putative uncharacterized protein; n=1; ... 86 4e-16
UniRef50_A1D6D8 Cluster: Signal peptidase I; n=16; Eurotiomyceti... 84 2e-15
UniRef50_Q0DW78 Cluster: Os02g0827900 protein; n=1; Oryza sativa... 79 6e-14
UniRef50_A3ACX9 Cluster: Putative uncharacterized protein; n=1; ... 78 8e-14
UniRef50_Q5KAU4 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13
UniRef50_UPI00004995E0 Cluster: signal peptidase; n=1; Entamoeba... 76 4e-13
UniRef50_A0DL56 Cluster: Chromosome undetermined scaffold_55, wh... 73 3e-12
UniRef50_A1D2V3 Cluster: Signal peptidase I, putative; n=1; Neos... 72 7e-12
UniRef50_Q019I3 Cluster: SPC21_MOUSE Microsomal signal peptidase... 71 9e-12
UniRef50_P15367 Cluster: Signal peptidase complex catalytic subu... 71 9e-12
UniRef50_Q2V8J6 Cluster: Signal peptidase; n=8; Plasmodium|Rep: ... 70 3e-11
UniRef50_Q4MYN7 Cluster: Signal peptidase, putative; n=3; Piropl... 67 1e-10
UniRef50_O74323 Cluster: Signal peptidase subunit Sec11; n=1; Sc... 67 1e-10
UniRef50_Q4DSS4 Cluster: Signal peptidase type I, putative; n=2;... 65 6e-10
UniRef50_Q4QIC4 Cluster: Signal peptidase type I, putative; n=4;... 64 2e-09
UniRef50_Q57Z71 Cluster: Signal peptidase type I, putative; n=1;... 62 4e-09
UniRef50_Q8SSG0 Cluster: SIGNAL PEPTIDASE 18kDa SUBUNIT; n=1; En... 60 2e-08
UniRef50_Q1DL14 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-06
UniRef50_Q7QYT3 Cluster: GLP_70_17657_16998; n=1; Giardia lambli... 48 7e-05
UniRef50_A2EJC9 Cluster: Clan SF, family S26, signal peptidase I... 47 2e-04
UniRef50_Q9UYQ4 Cluster: Signal peptidase; n=4; Thermococcaceae|... 44 0.002
UniRef50_A6TKK1 Cluster: Peptidase S26B, signal peptidase; n=1; ... 42 0.008
UniRef50_Q8XI29 Cluster: Signal peptidase type I; n=4; Clostridi... 41 0.011
UniRef50_O27497 Cluster: Signal peptidase; n=3; Methanobacteriac... 41 0.011
UniRef50_Q8TWK2 Cluster: Type I signal peptidase; n=1; Methanopy... 40 0.019
UniRef50_A7DR23 Cluster: Peptidase S26B, signal peptidase; n=1; ... 40 0.025
UniRef50_Q3IU50 Cluster: Signal peptidase I; n=1; Natronomonas p... 40 0.033
UniRef50_Q18RB3 Cluster: Peptidase S26B, signal peptidase; n=2; ... 39 0.044
UniRef50_Q5UZ22 Cluster: Signal sequence peptidase; n=1; Haloarc... 38 0.076
UniRef50_Q9HMR8 Cluster: Signal sequence peptidase; n=1; Halobac... 38 0.13
UniRef50_A7D7R6 Cluster: Signal peptidase I-like protein; n=1; H... 37 0.18
UniRef50_A0RTL4 Cluster: Signal peptidase I; n=1; Cenarchaeum sy... 36 0.31
UniRef50_Q1Q1Y2 Cluster: Putative uncharacterized protein; n=1; ... 36 0.41
UniRef50_Q9YAZ9 Cluster: Signal peptidase; n=1; Aeropyrum pernix... 36 0.41
UniRef50_O28483 Cluster: Signal sequence peptidase; n=1; Archaeo... 36 0.54
UniRef50_Q6ACL6 Cluster: Putative uncharacterized protein; n=1; ... 35 0.71
UniRef50_UPI000050F81C Cluster: COG0681: Signal peptidase I; n=1... 35 0.94
UniRef50_A5CQD8 Cluster: Putative signal peptidase I; n=1; Clavi... 35 0.94
UniRef50_Q977V4 Cluster: Signal peptidase; n=1; Methanococcus vo... 35 0.94
UniRef50_Q18DG6 Cluster: Signal sequence peptidase; n=1; Haloqua... 35 0.94
UniRef50_A7D506 Cluster: Peptidase S26B, signal peptidase precur... 35 0.94
UniRef50_Q67Q78 Cluster: Signal peptidase, type I; n=1; Symbioba... 34 1.2
UniRef50_A7D631 Cluster: Putative uncharacterized protein; n=1; ... 34 1.2
UniRef50_A4AFI0 Cluster: Peptidase S26B, eukaryotic signal pepti... 33 2.2
UniRef50_A1R8J4 Cluster: Putative uncharacterized protein; n=2; ... 33 2.2
UniRef50_A6VJ22 Cluster: Peptidase S26B, signal peptidase; n=2; ... 33 2.2
UniRef50_UPI00015BAAD0 Cluster: peptidase S26B, signal peptidase... 33 2.9
UniRef50_Q5WK13 Cluster: Signal peptidase I; n=1; Bacillus claus... 33 2.9
UniRef50_A2QQJ4 Cluster: Contig An08c0100, complete genome. prec... 33 2.9
UniRef50_Q6M084 Cluster: Microsomal signal peptidase 21 KD subun... 33 2.9
UniRef50_Q0W660 Cluster: Signal sequence peptidase; n=2; Archaea... 33 2.9
UniRef50_A3DP03 Cluster: Peptidase S26B, signal peptidase; n=1; ... 33 2.9
UniRef50_Q1U800 Cluster: SecY protein precursor; n=1; Lactobacil... 33 3.8
UniRef50_Q9KB06 Cluster: Signal peptidase; n=9; Bacillus|Rep: Si... 32 5.0
UniRef50_A2FMS6 Cluster: Putative uncharacterized protein; n=1; ... 32 5.0
UniRef50_Q8ZZH3 Cluster: Signal peptidase; n=4; Pyrobaculum|Rep:... 32 5.0
UniRef50_Q5UZ23 Cluster: Signal sequence peptidase; n=1; Haloarc... 32 6.6
UniRef50_A1RYI4 Cluster: Putative phage repressor; n=2; Thermofi... 32 6.6
>UniRef50_Q2F5L1 Cluster: Signal peptidase 18 kDa subunit; n=5;
Coelomata|Rep: Signal peptidase 18 kDa subunit - Bombyx
mori (Silk moth)
Length = 178
Score = 148 bits (358), Expect = 6e-35
Identities = 71/72 (98%), Positives = 71/72 (98%)
Frame = +3
Query: 36 MLESLFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAF 215
MLESLFDDVRRMNKRQFMYQVLS GMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAF
Sbjct: 1 MLESLFDDVRRMNKRQFMYQVLSLGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAF 60
Query: 216 HRGDLLFLTNYP 251
HRGDLLFLTNYP
Sbjct: 61 HRGDLLFLTNYP 72
Score = 127 bits (307), Expect = 1e-28
Identities = 62/80 (77%), Positives = 64/80 (80%)
Frame = +2
Query: 209 SFSQRRLAVFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNS 388
+F + L P EPVRVGEIV FKV GRDIPIVHRVLKLHEKNNG VKFLTKGDNNS
Sbjct: 59 AFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNS 118
Query: 389 VDDXXLXAQGQLWLTKKDVV 448
VDD L AQGQLWLTKKDVV
Sbjct: 119 VDDRGLYAQGQLWLTKKDVV 138
>UniRef50_Q9BY50 Cluster: Signal peptidase complex catalytic subunit
SEC11C; n=77; Eukaryota|Rep: Signal peptidase complex
catalytic subunit SEC11C - Homo sapiens (Human)
Length = 192
Score = 120 bits (289), Expect = 1e-26
Identities = 55/67 (82%), Positives = 63/67 (94%)
Frame = +3
Query: 48 LFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGD 227
+F D+++MNKRQ YQVL+F MIVSSALMIWKGL+V+TGSESPIVVVLSGSMEPAFHRGD
Sbjct: 18 IFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGD 77
Query: 228 LLFLTNY 248
LLFLTN+
Sbjct: 78 LLFLTNF 84
Score = 107 bits (256), Expect = 1e-22
Identities = 47/65 (72%), Positives = 54/65 (83%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLT 433
+P+R GEIV FKV GRDIPIVHRV+K+HEK+NG +KFLTKGDNN VDD L +GQ WL
Sbjct: 87 DPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLE 146
Query: 434 KKDVV 448
KKDVV
Sbjct: 147 KKDVV 151
>UniRef50_Q0DJD8 Cluster: Os05g0297900 protein; n=7; Oryza
sativa|Rep: Os05g0297900 protein - Oryza sativa subsp.
japonica (Rice)
Length = 180
Score = 93.1 bits (221), Expect = 3e-18
Identities = 42/62 (67%), Positives = 52/62 (83%)
Frame = +3
Query: 54 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 233
+ +R + RQ + Q++S GMIV+SAL+IWKGLMV TGSESP+VVVLSGSMEP F RGD+L
Sbjct: 9 ESIRSIQIRQVLAQIISLGMIVTSALIIWKGLMVATGSESPVVVVLSGSMEPGFKRGDIL 68
Query: 234 FL 239
FL
Sbjct: 69 FL 70
Score = 80.2 bits (189), Expect = 2e-14
Identities = 37/73 (50%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +2
Query: 233 VFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEK-NNGXVKFLTKGDNNSVDDXXLX 409
+F + +P+R GEIV F + GR+IPIVHRV+K+HE+ + V LTKGDNN DD L
Sbjct: 68 LFLHMSKDPIRTGEIVVFNIDGREIPIVHRVIKVHEREESAEVDILTKGDNNFGDDRLLY 127
Query: 410 AQGQLWLTKKDVV 448
A GQLWL + ++
Sbjct: 128 AHGQLWLHQHHIM 140
>UniRef50_Q9SSR2 Cluster: F6D8.18 protein; n=17; Magnoliophyta|Rep:
F6D8.18 protein - Arabidopsis thaliana (Mouse-ear cress)
Length = 180
Score = 89.0 bits (211), Expect = 4e-17
Identities = 41/62 (66%), Positives = 49/62 (79%)
Frame = +3
Query: 54 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 233
D ++ + RQ Q +S GMIV+SAL+IWK LM VTGSESP+VVVLSGSMEP F RGD+L
Sbjct: 9 DSIKSIQIRQLFTQAISLGMIVTSALIIWKALMCVTGSESPVVVVLSGSMEPGFKRGDIL 68
Query: 234 FL 239
FL
Sbjct: 69 FL 70
Score = 87.4 bits (207), Expect = 1e-16
Identities = 41/73 (56%), Positives = 52/73 (71%), Gaps = 1/73 (1%)
Frame = +2
Query: 233 VFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEK-NNGXVKFLTKGDNNSVDDXXLX 409
+F + +P+R GEIV F V GRDIPIVHRV+K+HE+ N G V LTKGDNN DD L
Sbjct: 68 LFLHMSKDPIRAGEIVVFNVDGRDIPIVHRVIKVHERENTGEVDVLTKGDNNYGDDRLLY 127
Query: 410 AQGQLWLTKKDVV 448
A+GQLWL + ++
Sbjct: 128 AEGQLWLHRHHIM 140
>UniRef50_A5APG1 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 174
Score = 85.8 bits (203), Expect = 4e-16
Identities = 39/73 (53%), Positives = 53/73 (72%)
Frame = +3
Query: 21 LIKLTMLESLFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGS 200
L ++ ++ D ++ + R + Q + GMIV+SALMIWKGL+ +TGS SP+VVVLSGS
Sbjct: 31 LREMGLIGESMDSIKTLQIRSTLSQAATLGMIVASALMIWKGLICITGSSSPVVVVLSGS 90
Query: 201 MEPAFHRGDLLFL 239
MEP F RGD+LFL
Sbjct: 91 MEPGFKRGDILFL 103
Score = 45.2 bits (102), Expect = 7e-04
Identities = 18/35 (51%), Positives = 28/35 (80%)
Frame = +2
Query: 233 VFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLH 337
+F ++ +P+R GEIV F V G+DIPIVHRV++++
Sbjct: 101 LFLRMTKDPIRTGEIVVFNVDGKDIPIVHRVIEIN 135
>UniRef50_A1D6D8 Cluster: Signal peptidase I; n=16;
Eurotiomycetidae|Rep: Signal peptidase I - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 192
Score = 83.8 bits (198), Expect = 2e-15
Identities = 39/56 (69%), Positives = 46/56 (82%)
Frame = +3
Query: 78 RQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
RQ + QVL+F +++S+A M+WKGL V T S SPIVVVLSGSMEPAF RGDLLFL N
Sbjct: 13 RQSLAQVLNFALVLSTAFMLWKGLSVFTASSSPIVVVLSGSMEPAFQRGDLLFLWN 68
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 15/87 (17%)
Frame = +2
Query: 227 LAVFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVK--------------- 361
L ++N+ P +GEIV + V G+DIPIVHRV++ + G K
Sbjct: 64 LFLWNRSP--RAELGEIVVYNVRGKDIPIVHRVVRTFPQIEGKAKKVKEVTEASSVPPNM 121
Query: 362 FLTKGDNNSVDDXXLXAQGQLWLTKKD 442
LTKGDNN DD L A+ Q +L +++
Sbjct: 122 LLTKGDNNIADDTELYAKNQDFLHREE 148
>UniRef50_Q0DW78 Cluster: Os02g0827900 protein; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Os02g0827900 protein -
Oryza sativa subsp. japonica (Rice)
Length = 191
Score = 78.6 bits (185), Expect = 6e-14
Identities = 37/73 (50%), Positives = 51/73 (69%), Gaps = 1/73 (1%)
Frame = +2
Query: 233 VFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEK-NNGXVKFLTKGDNNSVDDXXLX 409
+F Q+ P+R G+IV F GR+IPIVHRV+++HE+ +N V FLTKGDNN +DD L
Sbjct: 55 LFLQMSKHPIRTGDIVVFN-DGREIPIVHRVIEVHERRDNAQVDFLTKGDNNPMDDRILY 113
Query: 410 AQGQLWLTKKDVV 448
GQLWL + ++
Sbjct: 114 THGQLWLQQHHIM 126
Score = 78.2 bits (184), Expect = 8e-14
Identities = 35/57 (61%), Positives = 46/57 (80%)
Frame = +3
Query: 69 MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
M R + +++ GM++SSALMIWKGL+++TGSESP+VVVLS SME F RGD+LFL
Sbjct: 1 MQIRHALVHLITLGMVISSALMIWKGLIIMTGSESPLVVVLSESMELGFERGDILFL 57
>UniRef50_A3ACX9 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 133
Score = 78.2 bits (184), Expect = 8e-14
Identities = 35/57 (61%), Positives = 46/57 (80%)
Frame = +3
Query: 69 MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
M R + +++ GM++SSALMIWKGL+++TGSESP+VVVLS SME F RGD+LFL
Sbjct: 1 MQIRHALVHLITLGMVISSALMIWKGLIIMTGSESPLVVVLSESMELGFERGDILFL 57
Score = 37.5 bits (83), Expect = 0.13
Identities = 17/34 (50%), Positives = 25/34 (73%)
Frame = +2
Query: 233 VFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKL 334
+F Q+ P+R G+IV F GR+IPIVHRV+++
Sbjct: 55 LFLQMSKHPIRTGDIVVFN-DGREIPIVHRVIEV 87
>UniRef50_Q5KAU4 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 221
Score = 77.8 bits (183), Expect = 1e-13
Identities = 35/53 (66%), Positives = 44/53 (83%)
Frame = +3
Query: 87 MYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
++Q L+ +V+S LM+WKGL + T SESPIVVVLSGSMEPAF+RGD+LFL N
Sbjct: 34 LFQALNLLTVVASGLMMWKGLCLFTNSESPIVVVLSGSMEPAFYRGDILFLIN 86
Score = 58.0 bits (134), Expect = 9e-08
Identities = 28/64 (43%), Positives = 39/64 (60%)
Frame = +2
Query: 257 PVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTK 436
P VG+I +KV G +IPIVHRV++ H N + LTKGDNN DD L G W+ +
Sbjct: 91 PYEVGDITVYKVPGSEIPIVHRVIESHTTNTTQL-LLTKGDNNPGDDVVLY-NGLQWIER 148
Query: 437 KDVV 448
+ ++
Sbjct: 149 RHII 152
>UniRef50_UPI00004995E0 Cluster: signal peptidase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: signal peptidase - Entamoeba
histolytica HM-1:IMSS
Length = 189
Score = 75.8 bits (178), Expect = 4e-13
Identities = 36/76 (47%), Positives = 52/76 (68%), Gaps = 2/76 (2%)
Frame = +3
Query: 24 IKLTMLESL--FDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSG 197
I+L ++E ++ M R + V FG+IV+SA+++WK L + +E+PIVV+LSG
Sbjct: 5 IQLYLIEMFAPIQSLKSMGPRLIIQNVTQFGLIVASAVILWKALCIFFFTEAPIVVILSG 64
Query: 198 SMEPAFHRGDLLFLTN 245
SMEP F RGDL+FLTN
Sbjct: 65 SMEPGFKRGDLMFLTN 80
Score = 68.9 bits (161), Expect = 5e-11
Identities = 28/63 (44%), Positives = 43/63 (68%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTKK 439
+++G+IV + + + IPI+HRV+++H+ G V+FLTKGDNN VDD L G LWL
Sbjct: 87 IQIGDIVVYNLPSKGIPIIHRVIEIHKDTKGDVRFLTKGDNNPVDDRGLYG-GPLWLKPD 145
Query: 440 DVV 448
++
Sbjct: 146 QII 148
>UniRef50_A0DL56 Cluster: Chromosome undetermined scaffold_55, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_55,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 191
Score = 72.9 bits (171), Expect = 3e-12
Identities = 28/65 (43%), Positives = 46/65 (70%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLT 433
+P VG+++ +K+ ++IPIVHRVL++H++ + LTKGDNN VDD L + Q+WL
Sbjct: 84 KPFEVGDVIVYKLKDQEIPIVHRVLQIHKQQEIQILILTKGDNNQVDDRALYPKNQMWLK 143
Query: 434 KKDVV 448
+ D++
Sbjct: 144 RSDIM 148
Score = 66.5 bits (155), Expect = 3e-10
Identities = 31/56 (55%), Positives = 42/56 (75%)
Frame = +3
Query: 81 QFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNY 248
Q + Q++S +++ SAL IWK L VV+ SE P+VVVLS SM PA+ RGD+LFLT +
Sbjct: 27 QKILQLVSLAIVIGSALSIWKSLQVVSLSECPVVVVLSDSMVPAYGRGDILFLTYF 82
>UniRef50_A1D2V3 Cluster: Signal peptidase I, putative; n=1;
Neosartorya fischeri NRRL 181|Rep: Signal peptidase I,
putative - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 165
Score = 71.7 bits (168), Expect = 7e-12
Identities = 33/57 (57%), Positives = 44/57 (77%)
Frame = +3
Query: 69 MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
M+ R+F Q+LS + +S+ MIWKG V+TGS P++VV SGSMEPAF+RGDL+FL
Sbjct: 1 MDLRRFCAQLLSLVVTLSTLFMIWKGTNVITGSAYPLMVVTSGSMEPAFYRGDLVFL 57
Score = 50.0 bits (114), Expect = 2e-05
Identities = 27/70 (38%), Positives = 42/70 (60%), Gaps = 5/70 (7%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLK-----LHEKNNGXVKFLTKGDNNSVDDXXLXAQG 418
E +R G+I GR++P+VHR ++ L +NN LTKGDNN++DD L G
Sbjct: 62 ERIRAGDIPVVWFEGRELPMVHRAIQVSYEVLDGENNLKQHILTKGDNNALDDSSLYPAG 121
Query: 419 QLWLTKKDVV 448
Q ++ +++VV
Sbjct: 122 QGFVYRENVV 131
>UniRef50_Q019I3 Cluster: SPC21_MOUSE Microsomal signal peptidase 21
kDa subunit; n=2; Ostreococcus|Rep: SPC21_MOUSE
Microsomal signal peptidase 21 kDa subunit -
Ostreococcus tauri
Length = 207
Score = 71.3 bits (167), Expect = 9e-12
Identities = 34/57 (59%), Positives = 43/57 (75%)
Frame = +3
Query: 78 RQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNY 248
RQ + LS MI+++ALM+WK L++ T S+SPIVVVLSGSMEP RGDLL L N+
Sbjct: 42 RQSILSTLSLTMIIATALMLWKTLILCTMSDSPIVVVLSGSMEPGLRRGDLLVLENW 98
Score = 71.3 bits (167), Expect = 9e-12
Identities = 33/64 (51%), Positives = 43/64 (67%), Gaps = 3/64 (4%)
Frame = +2
Query: 266 VGEIVXFKVXGRDIPIVHRVLKLHEKN---NGXVKFLTKGDNNSVDDXXLXAQGQLWLTK 436
+GE V F V GRD+PIVHR+++ H +N + LTKGDNN DD L A GQ WLT+
Sbjct: 104 IGETVVFNVRGRDVPIVHRIVRAHGRNVRGDDERLMLTKGDNNFADDIGLYAPGQRWLTE 163
Query: 437 KDVV 448
+D+V
Sbjct: 164 EDIV 167
>UniRef50_P15367 Cluster: Signal peptidase complex catalytic subunit
SEC11; n=11; Ascomycota|Rep: Signal peptidase complex
catalytic subunit SEC11 - Saccharomyces cerevisiae
(Baker's yeast)
Length = 167
Score = 71.3 bits (167), Expect = 9e-12
Identities = 34/59 (57%), Positives = 43/59 (72%)
Frame = +3
Query: 69 MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
MN R + ++L+ + +SA M W+GL + T S SPIVVVLSGSMEPAF RGD+LFL N
Sbjct: 1 MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWN 59
Score = 59.3 bits (137), Expect = 4e-08
Identities = 28/63 (44%), Positives = 43/63 (68%), Gaps = 1/63 (1%)
Frame = +2
Query: 263 RVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTK-K 439
+VG++V ++V G+ IPIVHRVL+ H + LTKGDNN+ +D L A +++L K K
Sbjct: 65 QVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSK 124
Query: 440 DVV 448
++V
Sbjct: 125 EIV 127
>UniRef50_Q2V8J6 Cluster: Signal peptidase; n=8; Plasmodium|Rep:
Signal peptidase - Plasmodium falciparum
Length = 184
Score = 69.7 bits (163), Expect = 3e-11
Identities = 37/71 (52%), Positives = 50/71 (70%), Gaps = 2/71 (2%)
Frame = +3
Query: 45 SLFDDVRRM--NKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFH 218
SL D+R+ NKR + +L+ ++ +ALMIWK L+V TG ESP+VVVLSGSMEP ++
Sbjct: 10 SLVLDLRKTFRNKRDGLSHILNVICLLLNALMIWKLLVVFTGCESPVVVVLSGSMEPGYY 69
Query: 219 RGDLLFLTNYP 251
RGD L L + P
Sbjct: 70 RGDTLALYHPP 80
Score = 65.7 bits (153), Expect = 4e-10
Identities = 27/63 (42%), Positives = 39/63 (61%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTKK 439
+ G +V +++ GRDIPIVHR+L LH + L+KGDNN++DD L Q WL +
Sbjct: 82 IHAGNVVVYQINGRDIPIVHRMLSLHTSKDNKFHLLSKGDNNNIDDRGLYDPHQYWLENE 141
Query: 440 DVV 448
V+
Sbjct: 142 HVL 144
>UniRef50_Q4MYN7 Cluster: Signal peptidase, putative; n=3;
Piroplasmida|Rep: Signal peptidase, putative - Theileria
parva
Length = 183
Score = 67.3 bits (157), Expect = 1e-10
Identities = 29/48 (60%), Positives = 40/48 (83%)
Frame = +3
Query: 96 VLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
+LS ++ ALM WK +++TG++SP+VVVLSGSMEPAF+RGD+LFL
Sbjct: 29 ILSISSMIFVALMFWKIAILLTGTDSPVVVVLSGSMEPAFYRGDILFL 76
Score = 61.7 bits (143), Expect = 7e-09
Identities = 28/63 (44%), Positives = 41/63 (65%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTKK 439
+ G+IV FK+ R+IPIVHR + LH+ + + LTKGDNN V+D L + + WL K
Sbjct: 82 INSGDIVVFKLEDREIPIVHRAITLHQDKDN-LYVLTKGDNNRVNDRGLYPRNKNWLNDK 140
Query: 440 DVV 448
D++
Sbjct: 141 DLI 143
>UniRef50_O74323 Cluster: Signal peptidase subunit Sec11; n=1;
Schizosaccharomyces pombe|Rep: Signal peptidase subunit
Sec11 - Schizosaccharomyces pombe (Fission yeast)
Length = 189
Score = 67.3 bits (157), Expect = 1e-10
Identities = 33/62 (53%), Positives = 47/62 (75%)
Frame = +3
Query: 60 VRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
+++++ RQ + Q+L+ +++SSA M +K L VT ESP+VVVLS SMEP+F RGDLLFL
Sbjct: 1 MQKLSFRQGLAQILNLLLVLSSAYMGYKTLSFVTDCESPVVVVLSESMEPSFQRGDLLFL 60
Query: 240 TN 245
N
Sbjct: 61 DN 62
Score = 57.2 bits (132), Expect = 2e-07
Identities = 26/62 (41%), Positives = 40/62 (64%)
Frame = +2
Query: 257 PVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTK 436
PV +G+IV + + R IPIVHRV+KL+E N +TKGDNN +DD + + +L +
Sbjct: 84 PVGIGDIVVYSLPDRPIPIVHRVVKLYESEN-QTHLITKGDNNKIDDVAMFPKSINYLDR 142
Query: 437 KD 442
++
Sbjct: 143 EN 144
>UniRef50_Q4DSS4 Cluster: Signal peptidase type I, putative; n=2;
Trypanosoma cruzi|Rep: Signal peptidase type I, putative
- Trypanosoma cruzi
Length = 206
Score = 65.3 bits (152), Expect = 6e-10
Identities = 28/61 (45%), Positives = 41/61 (67%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTKK 439
V +G+++ F + GR +PIVHRV +HE + G + FLTKGDNN +DD L +G W+ +
Sbjct: 105 VNIGDVIVFSLPGRTVPIVHRVHGVHE-DGGTLLFLTKGDNNELDDRTLYPEGYHWVRDE 163
Query: 440 D 442
D
Sbjct: 164 D 164
Score = 52.4 bits (120), Expect = 4e-06
Identities = 21/43 (48%), Positives = 33/43 (76%)
Frame = +3
Query: 111 MIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
+ +S+ + W+ + ++ ++P+VVVLSGSMEPA+HRGDLL L
Sbjct: 57 LTLSAFFLGWRAVGIMANCDNPLVVVLSGSMEPAYHRGDLLLL 99
>UniRef50_Q4QIC4 Cluster: Signal peptidase type I, putative; n=4;
Leishmania|Rep: Signal peptidase type I, putative -
Leishmania major
Length = 180
Score = 63.7 bits (148), Expect = 2e-09
Identities = 29/66 (43%), Positives = 43/66 (65%)
Frame = +3
Query: 54 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 233
D + + R + QV++ + +S L+ W+G V+T E+ IVVVLSGSMEP +HRGD+L
Sbjct: 6 DTLLSLRIRDVVQQVVTISLFLSVVLVGWRGAAVITNCEASIVVVLSGSMEPGYHRGDVL 65
Query: 234 FLTNYP 251
L + P
Sbjct: 66 LLHHRP 71
Score = 63.7 bits (148), Expect = 2e-09
Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Frame = +2
Query: 248 P*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVK-FLTKGDNNSVDDXXLXAQGQL 424
P PV VG+I+ + + G+DIPIVHRV ++HE+ + +LTKGDNN DD L G+
Sbjct: 71 PEYPVEVGDIIVYTLPGQDIPIVHRVHRIHERAEDHKRLYLTKGDNNMNDDRFLFHDGRE 130
Query: 425 WLTKKDVV 448
W+ + ++
Sbjct: 131 WVEQDMII 138
>UniRef50_Q57Z71 Cluster: Signal peptidase type I, putative; n=1;
Trypanosoma brucei|Rep: Signal peptidase type I,
putative - Trypanosoma brucei
Length = 208
Score = 62.5 bits (145), Expect = 4e-09
Identities = 29/66 (43%), Positives = 43/66 (65%), Gaps = 1/66 (1%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVK-FLTKGDNNSVDDXXLXAQGQLWL 430
EP +G++V F + R IPIVHRV ++ +G + +LTKGDNN +DD L +G W+
Sbjct: 104 EPT-MGDVVVFSLPNRTIPIVHRVHRIRLLEDGVTRLYLTKGDNNEMDDRTLYPRGYHWV 162
Query: 431 TKKDVV 448
KKD++
Sbjct: 163 EKKDII 168
Score = 49.2 bits (112), Expect = 4e-05
Identities = 23/36 (63%), Positives = 26/36 (72%)
Frame = +3
Query: 138 WKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
W+ + VT ESP+VVVLSGSMEP RGDLL L N
Sbjct: 66 WRTAIAVTDCESPLVVVLSGSMEPFMFRGDLLVLHN 101
>UniRef50_Q8SSG0 Cluster: SIGNAL PEPTIDASE 18kDa SUBUNIT; n=1;
Encephalitozoon cuniculi|Rep: SIGNAL PEPTIDASE 18kDa
SUBUNIT - Encephalitozoon cuniculi
Length = 175
Score = 60.1 bits (139), Expect = 2e-08
Identities = 29/62 (46%), Positives = 40/62 (64%)
Frame = +3
Query: 60 VRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
++RM+ RQ + Q ++ V MIWK V+ ++SPIVVVLS SM P F RGD+L+L
Sbjct: 14 LKRMSIRQKLIQFVNAAYSVMGTYMIWKMFSVLLNNDSPIVVVLSESMSPGFERGDILWL 73
Query: 240 TN 245
N
Sbjct: 74 AN 75
Score = 46.4 bits (105), Expect = 3e-04
Identities = 26/60 (43%), Positives = 39/60 (65%)
Frame = +2
Query: 266 VGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLTKKDV 445
VG++ FK GR+IP VHR +K + G ++LTKGDNN DD L +G+ +LT+ ++
Sbjct: 80 VGDMTVFKF-GREIPCVHRCIK---QFGG--RYLTKGDNNLNDDVSLYPRGRNYLTRDEI 133
>UniRef50_Q1DL14 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 370
Score = 54.4 bits (125), Expect = 1e-06
Identities = 23/39 (58%), Positives = 30/39 (76%)
Frame = +3
Query: 132 MIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNY 248
M WK L + T + P +VVLSGSMEPAF RGD++FL+N+
Sbjct: 1 MAWKLLSLATNTSHPAMVVLSGSMEPAFQRGDIIFLSNW 39
Score = 46.0 bits (104), Expect = 4e-04
Identities = 21/65 (32%), Positives = 35/65 (53%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQLWLT 433
+ V VG+I G +P+VHR +++ G +TKGDN+ + D L GQ+++
Sbjct: 41 QQVEVGDIPVLWFEGNPLPMVHRAVEVQYDGTGRQLIMTKGDNSKLRDVALYPPGQIYVY 100
Query: 434 KKDVV 448
+ VV
Sbjct: 101 RTQVV 105
>UniRef50_Q7QYT3 Cluster: GLP_70_17657_16998; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_70_17657_16998 - Giardia lamblia
ATCC 50803
Length = 219
Score = 48.4 bits (110), Expect = 7e-05
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +3
Query: 36 MLESLFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAF 215
ML VR ++ +Y +L F + + +A M W L + ++ P +VVL+GSM P F
Sbjct: 1 MLSKTLQRVRSLSVFDVLYYILKFVLSICTAYMHWNLLKLFLNNDMPGIVVLTGSMVPGF 60
Query: 216 HRGDL 230
RGD+
Sbjct: 61 MRGDI 65
>UniRef50_A2EJC9 Cluster: Clan SF, family S26, signal peptidase
I-like serine peptidase; n=1; Trichomonas vaginalis
G3|Rep: Clan SF, family S26, signal peptidase I-like
serine peptidase - Trichomonas vaginalis G3
Length = 185
Score = 46.8 bits (106), Expect = 2e-04
Identities = 23/53 (43%), Positives = 34/53 (64%)
Frame = +3
Query: 93 QVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYP 251
+V++ +V S+++IW +V + P+VVVLS SMEP F RGDLL + P
Sbjct: 26 RVVNAANMVLSSVLIWTIFTLVFNNNMPLVVVLSNSMEPDFIRGDLLLAVSPP 78
Score = 41.5 bits (93), Expect = 0.008
Identities = 19/51 (37%), Positives = 29/51 (56%)
Frame = +2
Query: 269 GEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQ 421
GEI + + +PIVHR+++ H+ + LTKGDNN D L +G+
Sbjct: 86 GEICAYNIRTSPVPIVHRMIETHKYGQHKL-ILTKGDNNPTPDNFLYQRGE 135
>UniRef50_Q9UYQ4 Cluster: Signal peptidase; n=4;
Thermococcaceae|Rep: Signal peptidase - Pyrococcus
abyssi
Length = 155
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/49 (40%), Positives = 32/49 (65%)
Frame = +3
Query: 93 QVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
++LS + V ++ GL VV +++P+VVV SGSM P F+ GD++ L
Sbjct: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLL 55
Score = 35.9 bits (79), Expect = 0.41
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKN-NGXVK--FLTKGDNNSVDD 397
E ++VG+++ +K PI+HRV + + NG + F+T GDNN V D
Sbjct: 61 EEIKVGDVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPD 111
>UniRef50_A6TKK1 Cluster: Peptidase S26B, signal peptidase; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Peptidase S26B,
signal peptidase - Alkaliphilus metalliredigens QYMF
Length = 402
Score = 41.5 bits (93), Expect = 0.008
Identities = 25/55 (45%), Positives = 34/55 (61%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQL 424
++ G+I+ FK GR I I HR+ ++ E N G + F TKGDNNS +D L QL
Sbjct: 320 LKTGDIIQFK-KGR-ILISHRITEVVEGNEG-IAFSTKGDNNSSEDSDLVMPEQL 371
>UniRef50_Q8XI29 Cluster: Signal peptidase type I; n=4; Clostridium
perfringens|Rep: Signal peptidase type I - Clostridium
perfringens
Length = 166
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/57 (36%), Positives = 36/57 (63%)
Frame = +2
Query: 227 LAVFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
LA+ + + V+VG+I+ FK G+ + HRV++ +E+ F+TKGDNN+ +D
Sbjct: 58 LAIVKSIDADDVKVGDIITFKYEGK--VVTHRVVEKNEEG-----FITKGDNNNAND 107
>UniRef50_O27497 Cluster: Signal peptidase; n=3;
Methanobacteriaceae|Rep: Signal peptidase -
Methanobacterium thermoautotrophicum
Length = 144
Score = 41.1 bits (92), Expect = 0.011
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
E +R G+I+ + P++HRV+ + NG ++TKGDNN D
Sbjct: 61 ESIRKGDIIIYDATWFPEPVIHRVIGVETDRNGARYYITKGDNNQDPD 108
Score = 33.1 bits (72), Expect = 2.9
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +3
Query: 114 IVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
++ +A + ++ V S+ VVV SGSMEP F+RGD++ +
Sbjct: 7 VIEAAAYLLLLVLAVVASQHMNVVV-SGSMEPVFYRGDIVII 47
>UniRef50_Q8TWK2 Cluster: Type I signal peptidase; n=1; Methanopyrus
kandleri|Rep: Type I signal peptidase - Methanopyrus
kandleri
Length = 155
Score = 40.3 bits (90), Expect = 0.019
Identities = 17/51 (33%), Positives = 32/51 (62%)
Frame = +2
Query: 245 LP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
+P ++VG+++ +++ G+ IP+VHRV+ + +TKGDNN + D
Sbjct: 75 VPYRDIKVGDVIVYRLPGKPIPVVHRVIAKTPEG-----VITKGDNNPLPD 120
Score = 33.9 bits (74), Expect = 1.6
Identities = 15/36 (41%), Positives = 22/36 (61%)
Frame = +3
Query: 144 GLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYP 251
GL V G+ P+V V+S SM P ++ GD+L + P
Sbjct: 41 GLGFVLGTPDPVVTVISESMYPYYNVGDVLLVVGVP 76
>UniRef50_A7DR23 Cluster: Peptidase S26B, signal peptidase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Peptidase
S26B, signal peptidase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 236
Score = 39.9 bits (89), Expect = 0.025
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +3
Query: 69 MNKRQFMYQVLSFGMIVS-SALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
M K+ V+ +IV+ L+IW GL + G+ +P VV SGSM PA D+L ++
Sbjct: 1 MGKKSISKGVIKDIIIVAVGVLVIWIGLQIAFGTPNPFYVVASGSMIPALEVYDVLMVSG 60
Query: 246 Y 248
+
Sbjct: 61 H 61
>UniRef50_Q3IU50 Cluster: Signal peptidase I; n=1; Natronomonas
pharaonis DSM 2160|Rep: Signal peptidase I -
Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
Length = 276
Score = 39.5 bits (88), Expect = 0.033
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +3
Query: 117 VSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
V++ L++ L ++G P+V V SGSMEP RGDL+F+ +
Sbjct: 72 VAAVLLVGAVLFGISGIWPPMVAVESGSMEPNMERGDLIFIVD 114
>UniRef50_Q18RB3 Cluster: Peptidase S26B, signal peptidase; n=2;
Desulfitobacterium hafniense|Rep: Peptidase S26B, signal
peptidase - Desulfitobacterium hafniense (strain DCB-2)
Length = 180
Score = 39.1 bits (87), Expect = 0.044
Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Frame = +2
Query: 233 VFNQLP*EPVRVGE--IVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGD--NNSVDDX 400
+ ++ P EP R+ E IV F+ I + HR++++ E+ G +++LTKGD NN+ D
Sbjct: 104 IISRRPGEPDRLEESDIVTFRTRSGAI-VTHRIIEVIEEGEGNIRYLTKGDNPNNATDQE 162
Query: 401 XL 406
L
Sbjct: 163 AL 164
>UniRef50_Q5UZ22 Cluster: Signal sequence peptidase; n=1; Haloarcula
marismortui|Rep: Signal sequence peptidase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 236
Score = 38.3 bits (85), Expect = 0.076
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +3
Query: 81 QFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
+F V G V + L++ L V+G P+V + SGSMEP GD++F+
Sbjct: 26 RFGLYVRDIGTSVGAVLLVGGFLFAVSGVWPPLVAIESGSMEPHIDTGDMVFV 78
>UniRef50_Q9HMR8 Cluster: Signal sequence peptidase; n=1;
Halobacterium salinarum|Rep: Signal sequence peptidase -
Halobacterium salinarium (Halobacterium halobium)
Length = 239
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +3
Query: 84 FMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLT 242
F+ LS ++VS M+ L V+G P+V V SGSM+P +GDL+F+T
Sbjct: 30 FVRDALSSLLVVS---MVGLLLFSVSGVWPPLVAVESGSMQPNLQKGDLVFVT 79
>UniRef50_A7D7R6 Cluster: Signal peptidase I-like protein; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Signal
peptidase I-like protein - Halorubrum lacusprofundi ATCC
49239
Length = 365
Score = 37.1 bits (82), Expect = 0.18
Identities = 21/46 (45%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Frame = +3
Query: 111 MIVSSALMIWKGLMV--VTGSESPIVVVLSGSMEPAFHRGDLLFLT 242
M+ S A+++ GL++ V+G P+V V SGSMEP GDL+F+T
Sbjct: 129 MLSSVAIVLVIGLILFGVSGVWPPMVAVESGSMEPNIEVGDLVFVT 174
>UniRef50_A0RTL4 Cluster: Signal peptidase I; n=1; Cenarchaeum
symbiosum|Rep: Signal peptidase I - Cenarchaeum
symbiosum
Length = 324
Score = 36.3 bits (80), Expect = 0.31
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = +3
Query: 69 MNKRQFMYQVLSFGMIVSSAL-MIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
M + +++ G I + L +IW GL +V G+++P VV SGSM P D+L +
Sbjct: 2 MGGKSLKREIIKDGAIFAVGLAIIWIGLPLVFGTQNPFYVVSSGSMIPELEVYDVLIV 59
Score = 31.9 bits (69), Expect = 6.6
Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Frame = +2
Query: 248 P*EPVRVGEIVXF-KVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNN 385
P V+VG+++ F + G+D IVHRV + ++N ++ TKGD N
Sbjct: 64 PFSEVQVGDVIVFNRPSGQDRVIVHRVASIIDENPLTIR--TKGDAN 108
>UniRef50_Q1Q1Y2 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 191
Score = 35.9 bits (79), Expect = 0.41
Identities = 19/41 (46%), Positives = 26/41 (63%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDN 382
+R G+I+ F+ + IVHRVL + EK G F+TKGDN
Sbjct: 57 IRRGDIIAFRSENK--LIVHRVLTISEKGTG-FSFITKGDN 94
>UniRef50_Q9YAZ9 Cluster: Signal peptidase; n=1; Aeropyrum
pernix|Rep: Signal peptidase - Aeropyrum pernix
Length = 147
Score = 35.9 bits (79), Expect = 0.41
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +2
Query: 266 VGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
VG+IV ++ R I+HR++ +++ +G ++ KGDNN + D
Sbjct: 51 VGDIVVYRKGDR--LIIHRIIAVYQSESGFECYVVKGDNNPITD 92
>UniRef50_O28483 Cluster: Signal sequence peptidase; n=1;
Archaeoglobus fulgidus|Rep: Signal sequence peptidase -
Archaeoglobus fulgidus
Length = 189
Score = 35.5 bits (78), Expect = 0.54
Identities = 22/53 (41%), Positives = 35/53 (66%)
Frame = +3
Query: 81 QFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
QF+ V+S +IV A+++ G+ +TG+ +V V SGSMEP + GD++FL
Sbjct: 9 QFLKDVVSTLIIV--AVVVGGGI-AITGTWPFMVAVESGSMEPHLYPGDVVFL 58
>UniRef50_Q6ACL6 Cluster: Putative uncharacterized protein; n=1;
Leifsonia xyli subsp. xyli|Rep: Putative uncharacterized
protein - Leifsonia xyli subsp. xyli
Length = 396
Score = 35.1 bits (77), Expect = 0.71
Identities = 18/57 (31%), Positives = 32/57 (56%)
Frame = +2
Query: 227 LAVFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
+A+ ++P VR G+IV G+ +PI HRV++ G + + +GD N+ +D
Sbjct: 54 VALVREVPAAEVRRGDIVTVDRAGQ-LPITHRVVRTEPLPGGVTELVLRGDANAQND 109
>UniRef50_UPI000050F81C Cluster: COG0681: Signal peptidase I; n=1;
Brevibacterium linens BL2|Rep: COG0681: Signal peptidase
I - Brevibacterium linens BL2
Length = 463
Score = 34.7 bits (76), Expect = 0.94
Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Frame = +2
Query: 227 LAVFNQLP*EPVRVGEIVXFKVXGRDIPIVHRVLKL--HEKNNGXVKFLTKGDNNSVDD 397
+A +++P E + VG+I+ + +P+ HRV + + +G V F KGD N D
Sbjct: 68 IAFVHEIPAEKMEVGDIITADRGEKVLPVTHRVTSILDTDAQSGEVIFEMKGDANEAKD 126
>UniRef50_A5CQD8 Cluster: Putative signal peptidase I; n=1;
Clavibacter michiganensis subsp. michiganensis NCPPB
382|Rep: Putative signal peptidase I - Clavibacter
michiganensis subsp. michiganensis (strain NCPPB 382)
Length = 266
Score = 34.7 bits (76), Expect = 0.94
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = +2
Query: 227 LAVFNQLP*EPVRVGEIVXFKVXGRDIPIV-HRVLKLHEKNNGXVKFLTKGDNNSVDDXX 403
L V + + + +G++ +++ D ++ HR+ + ++G F KGDNN+ D
Sbjct: 92 LIVVRPVDPDALEIGDVATYQIRSGDPAVITHRITAIASASDGTRSFTFKGDNNASPDSL 151
Query: 404 LXAQGQL 424
GQ+
Sbjct: 152 PVTPGQI 158
>UniRef50_Q977V4 Cluster: Signal peptidase; n=1; Methanococcus
voltae|Rep: Signal peptidase - Methanococcus voltae
Length = 210
Score = 34.7 bits (76), Expect = 0.94
Identities = 13/39 (33%), Positives = 22/39 (56%)
Frame = +2
Query: 308 PIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQL 424
P++HR++ + NG + ++ KGDNN D L Q+
Sbjct: 119 PVIHRIIGNYTDKNGNIYYIIKGDNNQDRDPELVKPEQI 157
>UniRef50_Q18DG6 Cluster: Signal sequence peptidase; n=1;
Haloquadratum walsbyi DSM 16790|Rep: Signal sequence
peptidase - Haloquadratum walsbyi (strain DSM 16790)
Length = 285
Score = 34.7 bits (76), Expect = 0.94
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Frame = +3
Query: 27 KLTMLESLFDDVRR---MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSG 197
K T S+ +RR R+ +Y V+ ++V+ L+ L ++G P+V V SG
Sbjct: 69 KHTAESSILTRIRRGAVTTLRETLYSVI---VVVAIGLI----LFAISGVWPPMVAVESG 121
Query: 198 SMEPAFHRGDLLFLT 242
SMEP RGDL+ ++
Sbjct: 122 SMEPEMSRGDLILVS 136
>UniRef50_A7D506 Cluster: Peptidase S26B, signal peptidase
precursor; n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Peptidase S26B, signal peptidase precursor - Halorubrum
lacusprofundi ATCC 49239
Length = 353
Score = 34.7 bits (76), Expect = 0.94
Identities = 16/52 (30%), Positives = 27/52 (51%)
Frame = +2
Query: 269 GEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQL 424
G+++ F D+P+ HRV+ + ++ G + F T+GD N D L L
Sbjct: 74 GDVITFARGASDVPVTHRVIDVVDEGGG-LAFETQGDANEGPDPGLVPAANL 124
>UniRef50_Q67Q78 Cluster: Signal peptidase, type I; n=1;
Symbiobacterium thermophilum|Rep: Signal peptidase, type
I - Symbiobacterium thermophilum
Length = 196
Score = 34.3 bits (75), Expect = 1.2
Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 248 P*EPVRVGEIVXFKVXGR-DIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQL 424
P +R G+++ F+ D+ I HRV+ + N ++TKGD N D + Q+
Sbjct: 70 PEHEIREGDVITFRAADAPDMLITHRVIGIVSVNGEPAAYVTKGDANEAPDLVPVQRSQI 129
>UniRef50_A7D631 Cluster: Putative uncharacterized protein; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Putative
uncharacterized protein - Halorubrum lacusprofundi ATCC
49239
Length = 254
Score = 34.3 bits (75), Expect = 1.2
Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Frame = +3
Query: 108 GMIVSSALMIWKGLMV--VTGSESPIVVVLSGSMEPAFHRGDLLFLTN 245
G++ +A ++ ++V V G+ P V V SGSM P RGDL+ +T+
Sbjct: 33 GLLAPAAAVLLVAVVVAAVAGAWPPFVAVESGSMAPEVERGDLVVVTS 80
>UniRef50_A4AFI0 Cluster: Peptidase S26B, eukaryotic signal
peptidase; n=1; marine actinobacterium PHSC20C1|Rep:
Peptidase S26B, eukaryotic signal peptidase - marine
actinobacterium PHSC20C1
Length = 234
Score = 33.5 bits (73), Expect = 2.2
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Frame = +2
Query: 227 LAVFNQLP*EPVRVGEIVXFKVX-GRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD-- 397
L V + + +G+++ +++ G+ I HRV + ++G F +GDNN V D
Sbjct: 75 LVVVKPIDPNEIAMGDVITYQIESGKPGVITHRVTGVTNSSDGSRTFTLQGDNNDVADEL 134
Query: 398 --XXLXAQGQLW 427
+ G+LW
Sbjct: 135 QVLPIQVVGKLW 146
>UniRef50_A1R8J4 Cluster: Putative uncharacterized protein; n=2;
Arthrobacter aurescens TC1|Rep: Putative uncharacterized
protein - Arthrobacter aurescens (strain TC1)
Length = 248
Score = 33.5 bits (73), Expect = 2.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Frame = +2
Query: 248 P*EPVRVGEIVXFKVXGRDIPI-VHRVLKLHEKNNGXVKFLTKGD-NNSVDDXXLXAQGQ 421
P ++VG+++ + + D + HR+ ++ +G V TKGD NN +D QG+
Sbjct: 123 PVTDIKVGDVITYHIPVEDQRVETHRITEITTTADGGVAVQTKGDANNGIDPWIATLQGK 182
>UniRef50_A6VJ22 Cluster: Peptidase S26B, signal peptidase; n=2;
Methanococcus|Rep: Peptidase S26B, signal peptidase -
Methanococcus maripaludis C7
Length = 213
Score = 33.5 bits (73), Expect = 2.2
Identities = 14/39 (35%), Positives = 22/39 (56%)
Frame = +2
Query: 308 PIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQL 424
P++HRV+ ++G ++TKGDNN D L Q+
Sbjct: 117 PVIHRVIDTWTDSDGNKYYITKGDNNPTYDPELIRAEQV 155
>UniRef50_UPI00015BAAD0 Cluster: peptidase S26B, signal peptidase;
n=1; Ignicoccus hospitalis KIN4/I|Rep: peptidase S26B,
signal peptidase - Ignicoccus hospitalis KIN4/I
Length = 162
Score = 33.1 bits (72), Expect = 2.9
Identities = 19/51 (37%), Positives = 29/51 (56%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXL 406
+ V VG+I+ +K + I+HRV+K+ K ++TKGDNN D L
Sbjct: 61 DDVSVGDIIVYKSCQGPL-IIHRVIKV-VKVGSQYYYVTKGDNNPDSDYFL 109
>UniRef50_Q5WK13 Cluster: Signal peptidase I; n=1; Bacillus clausii
KSM-K16|Rep: Signal peptidase I - Bacillus clausii
(strain KSM-K16)
Length = 176
Score = 33.1 bits (72), Expect = 2.9
Identities = 17/48 (35%), Positives = 28/48 (58%)
Frame = +2
Query: 254 EPVRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
E +G++V F R + HR+++ E +NG + T+GDNN+V D
Sbjct: 70 EEPSIGDVVTFMAPERRL-FTHRIVEKFE-SNGKTYYKTQGDNNNVVD 115
>UniRef50_A2QQJ4 Cluster: Contig An08c0100, complete genome.
precursor; n=7; Trichocomaceae|Rep: Contig An08c0100,
complete genome. precursor - Aspergillus niger
Length = 907
Score = 33.1 bits (72), Expect = 2.9
Identities = 18/49 (36%), Positives = 24/49 (48%)
Frame = -2
Query: 280 NNFSNADRLSG*LVKNSKSPL*KAGSILPDSTTTIGLSLPVTTIKPFHI 134
+ FSN L LV P+ K+ + LP TT+ L+LP P HI
Sbjct: 101 SQFSNGTSLHSRLVSEPFVPILKSPAFLPKRPTTMALNLPSRRPPPLHI 149
>UniRef50_Q6M084 Cluster: Microsomal signal peptidase 21 KD subunit;
n=3; Methanococcus|Rep: Microsomal signal peptidase 21
KD subunit - Methanococcus maripaludis
Length = 207
Score = 33.1 bits (72), Expect = 2.9
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = +2
Query: 308 PIVHRVLKLHEKNNGXVKFLTKGDNNSVDDXXLXAQGQL 424
P++HRV+ + G ++TKGDNN D L Q+
Sbjct: 117 PVIHRVIDTWTDSEGNKYYITKGDNNPTYDPELIRAEQV 155
>UniRef50_Q0W660 Cluster: Signal sequence peptidase; n=2;
Archaea|Rep: Signal sequence peptidase - Uncultured
methanogenic archaeon RC-I
Length = 185
Score = 33.1 bits (72), Expect = 2.9
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
Frame = +3
Query: 126 ALMIWKGLMVV----TGSESPIVVVLSGSMEPAFHRGDLLFL 239
A++++ L+VV G+ P V ++S SMEP HRGD +F+
Sbjct: 26 AIILFLTLIVVLYGYAGTWPPAVSIISSSMEPHMHRGDEVFI 67
>UniRef50_A3DP03 Cluster: Peptidase S26B, signal peptidase; n=1;
Staphylothermus marinus F1|Rep: Peptidase S26B, signal
peptidase - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 163
Score = 33.1 bits (72), Expect = 2.9
Identities = 18/42 (42%), Positives = 24/42 (57%)
Frame = +3
Query: 111 MIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLF 236
+++ AL I L VTGS +PI VV SM P GD++F
Sbjct: 29 LVIILALNIRTILYNVTGSTTPIAVVKGYSMFPILREGDIVF 70
Score = 31.9 bits (69), Expect = 6.6
Identities = 15/46 (32%), Positives = 28/46 (60%)
Frame = +2
Query: 260 VRVGEIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDNNSVDD 397
+ VG+I+ ++ ++ I+HRV+++ N ++TKGDNN D
Sbjct: 79 IHVGDIIIYRGLSGEL-IIHRVIRVIINENKYY-YVTKGDNNQFPD 122
>UniRef50_Q1U800 Cluster: SecY protein precursor; n=1; Lactobacillus
reuteri 100-23|Rep: SecY protein precursor -
Lactobacillus reuteri 100-23
Length = 396
Score = 32.7 bits (71), Expect = 3.8
Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Frame = +3
Query: 30 LTMLESLFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVL---SGS 200
LTML + D MN+ + Q L+ G + + + GL + TG+ + V+L +GS
Sbjct: 84 LTMLRLFYFDTLSMNQLMKIQQWLTLGFAIIQSTAVTLGLKITTGTLDSLAVILMLTAGS 143
Query: 201 M 203
M
Sbjct: 144 M 144
>UniRef50_Q9KB06 Cluster: Signal peptidase; n=9; Bacillus|Rep:
Signal peptidase - Bacillus halodurans
Length = 191
Score = 32.3 bits (70), Expect = 5.0
Identities = 13/17 (76%), Positives = 15/17 (88%)
Frame = +3
Query: 183 VVLSGSMEPAFHRGDLL 233
VVLSGSMEPAFH G ++
Sbjct: 47 VVLSGSMEPAFHTGSII 63
>UniRef50_A2FMS6 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 541
Score = 32.3 bits (70), Expect = 5.0
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 272 EIVXFKVXGRDIPIVHRVLKLHEKNNGXVKFLTKGDN 382
E + FK I I+ R+L L + N G ++FL KG N
Sbjct: 287 EFIGFKERITTIDIIGRILCLADLNKGNIRFLLKGSN 323
>UniRef50_Q8ZZH3 Cluster: Signal peptidase; n=4; Pyrobaculum|Rep:
Signal peptidase - Pyrobaculum aerophilum
Length = 188
Score = 32.3 bits (70), Expect = 5.0
Identities = 16/30 (53%), Positives = 18/30 (60%)
Frame = +3
Query: 153 VVTGSESPIVVVLSGSMEPAFHRGDLLFLT 242
+ TG PI VV S SMEP GD +FLT
Sbjct: 23 LATGVAWPIAVVSSYSMEPTMRVGDFVFLT 52
>UniRef50_Q5UZ23 Cluster: Signal sequence peptidase; n=1; Haloarcula
marismortui|Rep: Signal sequence peptidase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 31.9 bits (69), Expect = 6.6
Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
Frame = +3
Query: 114 IVSSA---LMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFL 239
IVSSA L++ L V+G P+V + S SM+P GDL+F+
Sbjct: 69 IVSSAGSVLLVGVLLFAVSGVWPPLVAIESPSMDPHIKEGDLVFV 113
>UniRef50_A1RYI4 Cluster: Putative phage repressor; n=2; Thermofilum
pendens Hrk 5|Rep: Putative phage repressor -
Thermofilum pendens (strain Hrk 5)
Length = 281
Score = 31.9 bits (69), Expect = 6.6
Identities = 14/47 (29%), Positives = 25/47 (53%)
Frame = +3
Query: 93 QVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 233
+++ + + + L+ L V + P+ VV S SMEP H GD++
Sbjct: 159 EIVLYALTIVGLLVFLLSLRFVLSTPVPLAVVSSWSMEPVLHVGDVV 205
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 415,639,870
Number of Sequences: 1657284
Number of extensions: 7532787
Number of successful extensions: 17300
Number of sequences better than 10.0: 62
Number of HSP's better than 10.0 without gapping: 16299
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17106
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 23604537544
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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