Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= msgV0159.Seq
(538 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 105 5e-22
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 105 5e-22
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 94 2e-18
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 92 8e-18
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 90 3e-17
UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa dehydroge... 89 5e-17
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 89 5e-17
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 87 2e-16
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 85 7e-16
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 85 7e-16
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 85 7e-16
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 85 1e-15
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 85 1e-15
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 84 2e-15
UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 83 4e-15
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 83 5e-15
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 83 5e-15
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 82 9e-15
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 82 9e-15
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 82 9e-15
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 81 2e-14
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 81 2e-14
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 81 2e-14
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 81 2e-14
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 80 3e-14
UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 80 3e-14
UniRef50_Q47DJ5 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 80 4e-14
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 80 4e-14
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 79 5e-14
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 79 5e-14
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 79 5e-14
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 79 6e-14
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 79 8e-14
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 79 8e-14
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 78 1e-13
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 78 1e-13
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 78 1e-13
UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;... 78 1e-13
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 78 1e-13
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 78 1e-13
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 78 1e-13
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 78 1e-13
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 77 2e-13
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 77 3e-13
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 77 3e-13
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 76 6e-13
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 76 6e-13
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 76 6e-13
UniRef50_Q64428 Cluster: Trifunctional enzyme subunit alpha, mit... 76 6e-13
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 75 1e-12
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 75 1e-12
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 74 2e-12
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 74 2e-12
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 73 3e-12
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 73 3e-12
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 73 3e-12
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 73 4e-12
UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7... 73 4e-12
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 73 4e-12
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 73 6e-12
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 72 7e-12
UniRef50_P40939 Cluster: Trifunctional enzyme subunit alpha, mit... 72 7e-12
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 72 1e-11
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 72 1e-11
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 72 1e-11
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 72 1e-11
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 72 1e-11
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 71 1e-11
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 71 1e-11
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 71 2e-11
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 71 2e-11
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 71 2e-11
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 71 2e-11
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 71 2e-11
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 70 3e-11
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 70 3e-11
UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 70 4e-11
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 69 5e-11
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 5e-11
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 5e-11
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 69 5e-11
UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 7e-11
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 69 7e-11
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 69 7e-11
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 69 9e-11
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 69 9e-11
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 69 9e-11
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 68 1e-10
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 68 1e-10
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 68 2e-10
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 68 2e-10
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 67 2e-10
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 67 2e-10
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 67 2e-10
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 67 2e-10
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 67 3e-10
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 67 3e-10
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 67 3e-10
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 67 3e-10
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 66 4e-10
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 66 6e-10
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 66 6e-10
UniRef50_Q4REL3 Cluster: Chromosome 10 SCAF15123, whole genome s... 65 8e-10
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 65 8e-10
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 65 8e-10
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 65 8e-10
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 65 8e-10
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 65 1e-09
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 65 1e-09
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 65 1e-09
UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11; B... 64 1e-09
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 64 1e-09
UniRef50_Q12AF3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 64 2e-09
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 64 3e-09
UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 64 3e-09
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 64 3e-09
UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 64 3e-09
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 63 4e-09
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 62 6e-09
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 62 6e-09
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 62 6e-09
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 62 6e-09
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 62 6e-09
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 62 8e-09
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 62 8e-09
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 62 1e-08
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 62 1e-08
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 61 1e-08
UniRef50_A1VP66 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 61 2e-08
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 61 2e-08
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 60 2e-08
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 60 2e-08
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 60 2e-08
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 2e-08
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 3e-08
UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 60 3e-08
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 60 4e-08
UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex a... 59 6e-08
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 59 7e-08
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 59 7e-08
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 59 7e-08
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 59 7e-08
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 58 1e-07
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 58 1e-07
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 58 1e-07
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 58 1e-07
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 58 1e-07
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 58 1e-07
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 58 1e-07
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 58 2e-07
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 57 2e-07
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 57 2e-07
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 57 2e-07
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 57 2e-07
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 57 2e-07
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 57 2e-07
UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA dehydrog... 57 3e-07
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 57 3e-07
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 57 3e-07
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 56 5e-07
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 56 7e-07
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 56 7e-07
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 56 7e-07
UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3; Ni... 56 7e-07
UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE) (... 56 7e-07
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 55 1e-06
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 55 1e-06
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 54 2e-06
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 54 2e-06
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 54 2e-06
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ... 54 2e-06
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 2e-06
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 54 3e-06
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 54 3e-06
UniRef50_A3QGY2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 3e-06
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 53 4e-06
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 53 4e-06
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 6e-06
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 52 6e-06
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 8e-06
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 52 8e-06
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 52 1e-05
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 52 1e-05
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 52 1e-05
UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep... 51 1e-05
UniRef50_A3N0P8 Cluster: Putative fatty acid oxidation complex a... 51 1e-05
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 51 2e-05
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 51 2e-05
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 51 2e-05
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 50 3e-05
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 50 3e-05
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 50 3e-05
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 3e-05
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 50 3e-05
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 3e-05
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 4e-05
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 50 4e-05
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 49 6e-05
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 49 8e-05
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 48 1e-04
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 1e-04
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 1e-04
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 48 1e-04
UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 48 1e-04
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 48 2e-04
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 48 2e-04
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 48 2e-04
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 48 2e-04
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 2e-04
UniRef50_UPI00006A2DC9 Cluster: UPI00006A2DC9 related cluster; n... 47 2e-04
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 47 2e-04
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 47 2e-04
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 47 3e-04
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 47 3e-04
UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 47 3e-04
UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA dehydroge... 46 4e-04
UniRef50_Q7UXV2 Cluster: Fatty oxidation complex alpha subunit; ... 46 6e-04
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 46 6e-04
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 46 7e-04
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 46 7e-04
UniRef50_A3K5J4 Cluster: Putative fatty acid oxidation complex a... 44 0.002
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.002
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 44 0.002
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 44 0.002
UniRef50_A5ULU2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, FadB; ... 44 0.002
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 44 0.003
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 43 0.005
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 43 0.005
UniRef50_Q586V7 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 43 0.005
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 42 0.009
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 42 0.012
UniRef50_A4FJS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 41 0.021
UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4; L... 40 0.036
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.036
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 40 0.036
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 40 0.048
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 40 0.048
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 40 0.048
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.048
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 39 0.063
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 39 0.084
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 39 0.084
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 38 0.11
UniRef50_A2QI39 Cluster: Similarity to hypothetical 3-hydroxyacy... 38 0.11
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 38 0.11
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 38 0.15
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 38 0.15
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 38 0.15
UniRef50_Q5T751 Cluster: Late cornified envelope protein 1C; n=3... 37 0.26
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 36 0.45
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 36 0.45
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 36 0.45
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 36 0.45
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 36 0.59
UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 36 0.59
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 36 0.78
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 35 1.0
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 35 1.0
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 35 1.4
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 34 1.8
UniRef50_Q7RMI4 Cluster: Putative uncharacterized protein PY0219... 34 1.8
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 34 2.4
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 34 2.4
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 34 2.4
UniRef50_Q93E13 Cluster: FadB; n=1; Rhizobium leguminosarum bv. ... 33 3.1
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 33 4.2
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 33 4.2
UniRef50_Q5TA78 Cluster: Late cornified envelope protein 4A; n=2... 33 4.2
UniRef50_Q4RHT6 Cluster: Chromosome 8 SCAF15044, whole genome sh... 33 5.5
UniRef50_Q8EIT4 Cluster: Glutamate synthase, putative; n=13; Pro... 33 5.5
UniRef50_A5V511 Cluster: Enoyl-CoA hydratase/isomerase; n=1; Sph... 33 5.5
UniRef50_A5FRH3 Cluster: Nitroreductase; n=10; cellular organism... 33 5.5
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 33 5.5
UniRef50_P15265 Cluster: Sperm mitochondrial-associated cysteine... 33 5.5
UniRef50_Q4T8W5 Cluster: Chromosome undetermined SCAF7713, whole... 32 7.3
UniRef50_Q14JG6 Cluster: Cytochrome d terminal oxidase, polypept... 32 7.3
UniRef50_A3ADP3 Cluster: Putative uncharacterized protein; n=2; ... 32 7.3
UniRef50_Q48E59 Cluster: Ferric uptake regulation protein; n=7; ... 32 9.6
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 32 9.6
UniRef50_P35983 Cluster: E1B protein, small T-antigen; n=5; Cani... 32 9.6
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 105 bits (253), Expect = 5e-22
Identities = 43/82 (52%), Positives = 66/82 (80%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
A EHTI A+NTSS+ + +I + R+D+F GLHFFNPVPVM+L+EVIK+ S+ T++++
Sbjct: 138 AAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESL 197
Query: 187 MEWGKSVGKTCITCKDTPGFVV 252
+++ K++GK ++CKDTPGF+V
Sbjct: 198 VDFSKALGKHPVSCKDTPGFIV 219
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/94 (53%), Positives = 62/94 (65%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLK- 431
R+L PY EA+R+YERGDAS EDIDTAM+LGAGYPMGP EL DY GLD K I+ +
Sbjct: 221 RLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEM 280
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ NP+ +P L+ LV + +K G G Y Y
Sbjct: 281 DAENPLHQPSPSLNKLVAENK-FGKKTGEGFYKY 313
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 105 bits (253), Expect = 5e-22
Identities = 44/78 (56%), Positives = 62/78 (79%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
+IL TNTSS + + G++ K +FGGLHFFNPVPVM+LLEVI+SD S++TY ++++G
Sbjct: 125 SILTTNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFG 184
Query: 199 KSVGKTCITCKDTPGFVV 252
+VGKT + CKD+PGF+V
Sbjct: 185 TAVGKTTVACKDSPGFIV 202
Score = 91.5 bits (217), Expect = 1e-17
Identities = 50/94 (53%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL-AVMLK 431
R+L PY EA RMYERGDAS DID AM+LGAG+PMGP ELADY GLD K ++ K
Sbjct: 204 RLLIPYFFEAARMYERGDASMTDIDEAMKLGAGHPMGPFELADYIGLDTVKFVMDGWAAK 263
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+FE ++D LV G+ RK G G Y Y
Sbjct: 264 YPEVQLFEASPLVDKLVAEGK-LGRKTGDGFYSY 296
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/95 (51%), Positives = 63/95 (66%), Gaps = 2/95 (2%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L PY +++RM ERGDA+ EDIDTAMR G YPMGP+EL DY GLD+ +S L + +E
Sbjct: 207 RLLIPYLMDSIRMLERGDATKEDIDTAMRFGTSYPMGPIELCDYVGLDVLQSTLKI-FRE 265
Query: 435 T--GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T G+ F PI ++D LV G+ RK G Y Y
Sbjct: 266 TIPGDARFAPIPLMDKLVAEGK-LGRKTKQGFYTY 299
Score = 78.6 bits (185), Expect = 8e-14
Identities = 35/81 (43%), Positives = 53/81 (65%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P++ +L TNTSS+ ++ + I+ F GLHFFNPVPVM+L+EV+ +D S +T +
Sbjct: 125 PQNCMLITNTSSLKLSQMLPVIQNPALFAGLHFFNPVPVMKLVEVVSTDETSPETTNFLF 184
Query: 190 EWGKSVGKTCITCKDTPGFVV 252
+ K + K + KDTPGF+V
Sbjct: 185 NFCKEIKKLPVAAKDTPGFIV 205
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 91.9 bits (218), Expect = 8e-18
Identities = 43/80 (53%), Positives = 55/80 (68%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ TI ATNTSSIS+ + + +K F G+HFFNPVPVM+L+EVI + + T +E
Sbjct: 113 DDTIYATNTSSISITEMAALVKNPANFIGMHFFNPVPVMKLVEVIPALQTAPATKDLALE 172
Query: 193 WGKSVGKTCITCKDTPGFVV 252
K +GKT ITCKDTPGFVV
Sbjct: 173 MAKKIGKTAITCKDTPGFVV 192
Score = 78.6 bits (185), Expect = 8e-14
Identities = 39/94 (41%), Positives = 55/94 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ PY +A+R+ E G ASAEDIDTAM+LG PMGPLE D+ G+D+ ++ + +
Sbjct: 194 RLFVPYIIDAVRLLEEGVASAEDIDTAMKLGCNMPMGPLEFQDFAGVDIGYHVINIFHEY 253
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
F G+L ++K G RK G G Y Y+
Sbjct: 254 MKQERFAAPGLLRNMIKAG-YVGRKAGKGFYDYS 286
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 89.8 bits (213), Expect = 3e-17
Identities = 42/84 (50%), Positives = 56/84 (66%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+L E TILATNTSS+S+ I S KR DK G+HFFNPVP+M+L+EVI S+ T+
Sbjct: 103 ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFD 162
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
+ E KS+ K + ++PGFVV
Sbjct: 163 TVFELSKSINKVPVDVSESPGFVV 186
Score = 71.7 bits (168), Expect = 1e-11
Identities = 41/94 (43%), Positives = 54/94 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA+ +Y G AS E+ID AM+LGA +PMGPL L D GLD+ +I+ V+ E
Sbjct: 188 RILIPMINEAVGIYADGVASKEEIDEAMKLGANHPMGPLALGDLIGLDVVLAIMNVLYTE 247
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ + +L +V R RK G Y YN
Sbjct: 248 FGDTKYTAHPLLAKMV-RANQLGRKTKIGFYDYN 280
>UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa
dehydrogenase, putative; n=2; Trypanosoma cruzi|Rep:
Short chain 3-hydroxyacyl-coa dehydrogenase, putative -
Trypanosoma cruzi
Length = 320
Score = 89.4 bits (212), Expect = 5e-17
Identities = 46/94 (48%), Positives = 60/94 (63%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLK- 431
R+L PY EA R+ ERGDA+ ED+D AM+LG G+PMGP LAD G+D+ K I K
Sbjct: 226 RLLIPYELEACRIVERGDATVEDVDLAMKLGCGHPMGPFVLADSIGIDVLKLIADAWHKE 285
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
E NP+F+P ++D V +G+ RK G G Y Y
Sbjct: 286 EPENPLFKPSKLIDEKVAQGK-LGRKTGEGFYKY 318
Score = 80.6 bits (190), Expect = 2e-14
Identities = 35/83 (42%), Positives = 54/83 (65%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP+ + TNTSS+SV + R D+F GLHFF+PVP+M+L+EV+K+ S+ T
Sbjct: 142 MAPKECVFCTNTSSLSVGEQAAVTGRPDRFAGLHFFSPVPMMKLVEVVKAAKTSQSTLDR 201
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
++E+ K + K + DT GF+V
Sbjct: 202 ILEYAKMLNKQPVMATDTKGFIV 224
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 89.4 bits (212), Expect = 5e-17
Identities = 41/84 (48%), Positives = 57/84 (67%), Gaps = 2/84 (2%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGI--KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
A I ATNTSS+SV I +R+ KF GLHFFNPVP M+L+E+I++ S++TY+
Sbjct: 143 AKSDCIFATNTSSLSVTEIAEACSPERQAKFAGLHFFNPVPAMKLVEIIRTPQTSQETYE 202
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
+ E +GK+ +TC DTPGF+V
Sbjct: 203 TLREVTLQMGKSPVTCNDTPGFIV 226
Score = 65.7 bits (153), Expect = 6e-10
Identities = 29/37 (78%), Positives = 32/37 (86%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMG 365
R+L PY EA+RM ERGDA+AEDIDTAM LGAGYPMG
Sbjct: 228 RLLVPYLLEAIRMIERGDATAEDIDTAMELGAGYPMG 264
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 87.0 bits (206), Expect = 2e-16
Identities = 40/81 (49%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E ILATNTS+I + I G+K+K K G+HFFNP V++L+EVI+SD+ ++ ++A+ +
Sbjct: 109 EDAILATNTSNIRLTEIAEGVKKKGKVVGMHFFNPPVVLKLVEVIRSDYTEDEVFEAVYD 168
Query: 193 WGKSVGKTCI-TCKDTPGFVV 252
+ K +GK I KDTPGFVV
Sbjct: 169 FSKKIGKIPIKVYKDTPGFVV 189
Score = 42.7 bits (96), Expect = 0.005
Identities = 31/91 (34%), Positives = 41/91 (45%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI AP S + ++G A E++D R G PMGP EL DY G+D L KE
Sbjct: 191 RINAPESLYFCLVLDKGIAKPEEVDRFAR-SQGLPMGPYELMDYVGIDTVYHSLEYYAKE 249
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
+P + V + L + K G G Y
Sbjct: 250 L-SPDYAKCQVYNKLYNE-KKLGLKTGEGFY 278
Score = 35.9 bits (79), Expect = 0.59
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELA-DYTGLDLKKSILAVMLKETGNPVFE 455
EA+++ E S EDI+ ++LG P GP+ +A T ++ KS L + + G VF+
Sbjct: 308 EAVKIIEEKIVSPEDIEIGVKLGMNRPFGPITVAKGLTNAEI-KSKLESLYNKFGVSVFQ 366
Query: 456 P 458
P
Sbjct: 367 P 367
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 85.4 bits (202), Expect = 7e-16
Identities = 45/94 (47%), Positives = 58/94 (61%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA+ +Y G AS EDIDT+M+LGA +PMGPL L D GLD+ +I+ V+ KE
Sbjct: 189 RILIPMINEAIGIYAEGIASVEDIDTSMKLGANHPMGPLALGDLIGLDVCLAIMDVLFKE 248
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
TG+ + +L V+ G RK G G Y YN
Sbjct: 249 TGDSKYRAHSLLRKYVRAG-WLGRKTGRGFYNYN 281
Score = 79.8 bits (188), Expect = 4e-14
Identities = 34/83 (40%), Positives = 54/83 (65%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ E TILA+NTSS+S+ + S R D+ G+HFFNP +M+L+EVI+ S++T+
Sbjct: 105 ICKEETILASNTSSLSITEVASATNRPDRVIGMHFFNPATIMKLVEVIRGMATSQETFDK 164
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ +++GKT + + PGFVV
Sbjct: 165 VKAMSEAIGKTPVEVAEAPGFVV 187
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 85.4 bits (202), Expect = 7e-16
Identities = 39/83 (46%), Positives = 53/83 (63%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A + ILA+NTSS + +G R F GLHFFNPV +M+L+EVIK+ ED Y+
Sbjct: 134 VAGANAILASNTSSFPITQLGEASGRTSNFLGLHFFNPVQMMKLVEVIKTKDTKEDVYKL 193
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ KS+GK + C DTPGF+V
Sbjct: 194 GFAFSKSIGKEPVACGDTPGFIV 216
Score = 70.1 bits (164), Expect = 3e-11
Identities = 42/92 (45%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P+ A+ L M +RG AS +DID AM GAG PMGPL LADY GLD+ IL +
Sbjct: 218 RLLVPFLAQGLLMLDRGVASVQDIDVAMMYGAGMPMGPLTLADYVGLDVCMHILEGWTSQ 277
Query: 435 TGN-PVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
N P F L V G+ RK G G +
Sbjct: 278 YPNEPAFVIPQPLKAKVAAGK-LGRKTGEGFW 308
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 85.4 bits (202), Expect = 7e-16
Identities = 36/84 (42%), Positives = 58/84 (69%), Gaps = 2/84 (2%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGI--KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
AP+ + A+NTSS+S+ + + +R++ FGG H FNPVP M+L+EV+++ S DT+
Sbjct: 154 APKDALFASNTSSLSITDVAEAVSAQRQELFGGFHAFNPVPQMKLVEVVRTTKTSNDTFD 213
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
++ E K +GKT + C D+PGF+V
Sbjct: 214 SLTEVAKRMGKTPVACIDSPGFIV 237
Score = 76.2 bits (179), Expect = 5e-13
Identities = 32/48 (66%), Positives = 40/48 (83%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD 398
R+L PY EA+R+ ERG+A+A+D+D AM+LGAGYPMGP ELAD GLD
Sbjct: 239 RLLVPYMLEAIRLVERGEATAKDVDIAMKLGAGYPMGPFELADLVGLD 286
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 85.0 bits (201), Expect = 1e-15
Identities = 40/83 (48%), Positives = 54/83 (65%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L E +LATNTSS+SV IG+ R D+ G+HFFNPVP MRL+EV+ D E QA
Sbjct: 105 LCREDVVLATNTSSLSVTQIGALAGRADRVVGMHFFNPVPAMRLVEVVGGDASGEAALQA 164
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ +++GK + +DTPGF+V
Sbjct: 165 TVSLAEAMGKVPVRVRDTPGFIV 187
Score = 60.1 bits (139), Expect = 3e-08
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSI-LAVMLK 431
R+ P++ EALR+ A+A ID RL G+ MGP EL D G+D+ ++ +V +
Sbjct: 189 RVARPFTGEALRLLGDQVATAAQIDRIARLACGFRMGPFELMDLVGMDINFAVHRSVYEQ 248
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G+P F P + + +VK G RK G G Y Y
Sbjct: 249 FFGDPRFRPHPLQERMVKAGR-LGRKTGQGWYRY 281
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/79 (43%), Positives = 44/79 (55%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+LA EA + G A+AE IDTAM+LG YP+GPLE AD G D ++L + +E
Sbjct: 434 RLLACLINEAAFALQEGIATAEAIDTAMQLGLNYPLGPLEWADELGPDKVLAVLEGLQRE 493
Query: 435 TGNPVFEPIGVLDXLVKRG 491
TG + P L V G
Sbjct: 494 TGEERYRPAPYLRKRVLAG 512
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 84.6 bits (200), Expect = 1e-15
Identities = 41/76 (53%), Positives = 53/76 (69%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTSSIS+ I + KR DK G+HFFNPVPVM+L+EVI+ S++TYQA+ +
Sbjct: 113 ILATNTSSISITKIAAVTKRPDKVIGMHFFNPVPVMKLVEVIRGLATSDETYQAVKVLSE 172
Query: 202 SVGKTCITCKDTPGFV 249
+ KT + D PGFV
Sbjct: 173 KLEKTPVEVNDAPGFV 188
Score = 66.9 bits (156), Expect = 3e-10
Identities = 36/93 (38%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA+ G A+ E +D +LG +PMGPL LAD+ GLD+ I+ V+
Sbjct: 191 RVLMPLLNEAMYAVMEGVATPEAVDEVFKLGMAHPMGPLTLADFIGLDVCLDIMRVLQTG 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G+P + P +L +V G RK G G Y Y
Sbjct: 251 LGDPKYRPCPLLIKMVDAG-WLGRKSGRGFYKY 282
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 84.2 bits (199), Expect = 2e-15
Identities = 38/80 (47%), Positives = 53/80 (66%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E ILATNTSSIS+ AIG+ +KR ++ G+HFFNP P+M+L+EV+ S + Q
Sbjct: 115 EDAILATNTSSISITAIGAALKRPERLVGMHFFNPAPIMKLVEVVSGLATSPEVAQITHA 174
Query: 193 WGKSVGKTCITCKDTPGFVV 252
++ GKT + K TPGF+V
Sbjct: 175 TARAWGKTAVHVKSTPGFIV 194
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/63 (39%), Positives = 33/63 (52%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LA + EA +G A E ID AMR G YP GP+E A GL ++L ++
Sbjct: 398 RTLALIANEAFEAVLQGVADEESIDLAMRFGVNYPRGPIEWARDIGLARILAVLDQLMTM 457
Query: 435 TGN 443
TG+
Sbjct: 458 TGD 460
>UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 293
Score = 83.0 bits (196), Expect = 4e-15
Identities = 36/83 (43%), Positives = 59/83 (71%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A I A+NTSSIS+ + + KR ++F GLHFFNPVP+M+L+EVI++ S++ ++A
Sbjct: 106 VAKPDAIFASNTSSISITELMAATKRPERFIGLHFFNPVPLMKLVEVIRTIATSDEVFEA 165
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+++G +GK + KD+ GF+V
Sbjct: 166 AVDFGTKLGKVPVRTKDSSGFIV 188
Score = 74.9 bits (176), Expect = 1e-12
Identities = 42/93 (45%), Positives = 49/93 (52%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L PY +A+R YE G S DID AM+LG GYPMGP L D+ GLD I VM E
Sbjct: 190 RLLVPYLLDAIRAYEEGVGSIVDIDQAMKLGCGYPMGPFTLLDFVGLDTCYYITHVMFDE 249
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
F +L +V G RK G G Y Y
Sbjct: 250 FREKRFAAPPLLKRMVLAG-WYGRKTGKGFYDY 281
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 82.6 bits (195), Expect = 5e-15
Identities = 38/79 (48%), Positives = 56/79 (70%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE TI+A+NTS+I ++ + + ++RKDKF G+H+FNP PVMRL+EVI+ S++T+ +
Sbjct: 116 PE-TIIASNTSAIMISDLATAVERKDKFIGMHWFNPAPVMRLIEVIRGALTSDETFNITV 174
Query: 190 EWGKSVGKTCITCKDTPGF 246
E K +GK I D PGF
Sbjct: 175 ELSKKMGKIPIEAGDGPGF 193
Score = 59.3 bits (137), Expect = 6e-08
Identities = 33/87 (37%), Positives = 44/87 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R + + EA+R++E G A ++ID +L G+PMGP EL D GLD I + E
Sbjct: 197 RFINSWLVEAVRLFEIGIAGIKEIDEMCKLAFGFPMGPFELMDLIGLDTALHIAEYLYNE 256
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPG 515
T P + L LV G RKPG
Sbjct: 257 TKEPHYAAPNTLKKLVLSG-YVGRKPG 282
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 82.6 bits (195), Expect = 5e-15
Identities = 37/84 (44%), Positives = 53/84 (63%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++ P T+L TNTSSIS+ AI + IK ++ GLHFFNP PVM+L+EV+ + + +
Sbjct: 108 EVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVE 167
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
+ E S GK + C TPGF+V
Sbjct: 168 QLCELTLSWGKQPVRCHSTPGFIV 191
Score = 56.8 bits (131), Expect = 3e-07
Identities = 36/92 (39%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ PY +EA R E A+ E ID A+R GAG+PMGPLEL D G D+ ++ +
Sbjct: 193 RVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNA 252
Query: 435 TGNP-VFEPIGVLDXLVKRGEXXDRKPGXGIY 527
F P V LV G +K G G+Y
Sbjct: 253 FWQERRFLPSLVQQELVIGGR-LGKKSGLGVY 283
Score = 46.8 bits (106), Expect = 3e-04
Identities = 27/72 (37%), Positives = 35/72 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R +A EAL ++G AS +DIDTAMRLG YP GPL G +L +
Sbjct: 392 RTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQHH 451
Query: 435 TGNPVFEPIGVL 470
G + P +L
Sbjct: 452 YGEERYRPCSLL 463
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 81.8 bits (193), Expect = 9e-15
Identities = 38/83 (45%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP H ILA+NTSSI + I KR DK G+HFFNP +++L+EV++ S++T +
Sbjct: 135 APPHAILASNTSSIPITEIAKATKRPDKVVGMHFFNPPVILKLVEVVRGKETSDETVKIT 194
Query: 187 MEWGKSVGKTCITC-KDTPGFVV 252
+E K +GK I KD PGF+V
Sbjct: 195 VELAKKMGKVPIVVNKDVPGFIV 217
Score = 52.8 bits (121), Expect = 5e-06
Identities = 32/93 (34%), Positives = 47/93 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI+A + E + ERG + E +D A+R +PMG ELADY GLD+ ++ M +
Sbjct: 219 RIMARFLNEGCWLVERGVYTKEQVDAALRYKLNFPMGAFELADYVGLDVLVHLMEAMKER 278
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
N P+ L++ G+ K G G Y Y
Sbjct: 279 GMNLTICPL--FKKLLEEGK-LGVKSGEGFYKY 308
Score = 49.2 bits (112), Expect = 6e-05
Identities = 30/85 (35%), Positives = 43/85 (50%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
E + E G A E++DTA LG PMG L+L D GLD + ++ G + P
Sbjct: 339 EGAWLVENGVAGPEEVDTATVLGLNLPMGILKLGDSLGLDNVLDSINEKKEKYGLEDYRP 398
Query: 459 IGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ +L+ +VK G+ K G G Y Y
Sbjct: 399 VQLLENMVKEGK-CGVKCGKGFYEY 422
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 81.8 bits (193), Expect = 9e-15
Identities = 37/84 (44%), Positives = 54/84 (64%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++ P H +LATNTSS+SV AIG+ + + GLHFFNPVP+M+L+EVI +D
Sbjct: 112 EVCPRHAVLATNTSSLSVTAIGAALADPSRLIGLHFFNPVPLMKLVEVIPGARTRQDLSA 171
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
++E + +G + DTPGF+V
Sbjct: 172 DLVELVRRLGHQPVLATDTPGFLV 195
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/68 (41%), Positives = 39/68 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+LA A + E+ DIDTA+R+G GYP GPLE ++ G + +IL M E
Sbjct: 420 RLLASIVNTACGIAEQRIGRPADIDTAVRVGLGYPRGPLEWGEHAGRERILAILRNMHAE 479
Query: 435 TGNPVFEP 458
TG+P + P
Sbjct: 480 TGDPRYRP 487
Score = 47.2 bits (107), Expect = 2e-04
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +3
Query: 273 SAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL-AVMLKETGNPV 449
+ EAL++ D+D R G MGP EL D TGLD+ +L ++ G+P
Sbjct: 203 ATEALQIMSESAVEPSDVDRIARDVLGLRMGPFELLDLTGLDVSHPVLESIWSGFYGDPR 262
Query: 450 FEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
P G+ ++ G RK G G Y Y
Sbjct: 263 LRPSGITRSRLEAG-LLGRKTGEGFYRY 289
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 81.8 bits (193), Expect = 9e-15
Identities = 36/77 (46%), Positives = 52/77 (67%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILA+NTSSIS+ AI S +K ++F GLHFFNP PVM+L+EVI+ +++ + +W +
Sbjct: 116 ILASNTSSISITAIASALKSPERFIGLHFFNPAPVMKLVEVIQGVATADNIAETAQQWAR 175
Query: 202 SVGKTCITCKDTPGFVV 252
S GK + PGF+V
Sbjct: 176 SCGKKSVLACSIPGFIV 192
Score = 52.8 bits (121), Expect = 5e-06
Identities = 33/95 (34%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ P+ AE LR E A+ +DID MR AG+ MGP EL D G D+ ++ +
Sbjct: 194 RVARPFYAEGLRALEESVATIDDIDHLMRASAGFNMGPFELMDLIGHDVNYAVTKSVFDA 253
Query: 435 T-GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+ ++P LV G RK G G Y Y+
Sbjct: 254 CYQDRRYQPSLAQKELVDAG-FFGRKSGRGFYDYS 287
Score = 43.6 bits (98), Expect = 0.003
Identities = 26/75 (34%), Positives = 36/75 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R L+ S EAL + + AS DID AM+ G YP+GP+E + G K L +
Sbjct: 429 RTLSMLSNEALDLANKKGASEADIDIAMKSGVNYPLGPVEWGEKLGWKNVKETLESLTAF 488
Query: 435 TGNPVFEPIGVLDXL 479
G + P +L L
Sbjct: 489 YGEERYRPSPLLRQL 503
>UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Serratia proteamaculans 568|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding - Serratia
proteamaculans 568
Length = 509
Score = 81.0 bits (191), Expect = 2e-14
Identities = 35/80 (43%), Positives = 53/80 (66%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ I+ATNTSS+S+N + +G++ +F GLHFFNP P+M+L+E+I S S T +
Sbjct: 115 KEAIIATNTSSLSLNKLAAGVENNARFIGLHFFNPAPLMKLIEIIPSYFTSRATSLRCQQ 174
Query: 193 WGKSVGKTCITCKDTPGFVV 252
++GK + CK TPGF+V
Sbjct: 175 LVTAIGKQFVVCKATPGFIV 194
Score = 45.6 bits (103), Expect = 7e-04
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ P+ E R+ E A A ID A++ G + MGPLEL D+ G D+ + + + ++
Sbjct: 196 RMARPFYLEGFRLLEENVALAPQIDRALKAGGHFRMGPLELTDFIGQDINYQVSSQIWQD 255
Query: 435 TG-NPVFEPIGVLDXLVKRG 491
+P + P + LV G
Sbjct: 256 MQYDPRYTPGHLQRSLVDAG 275
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 81.0 bits (191), Expect = 2e-14
Identities = 35/83 (42%), Positives = 55/83 (66%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P HT LA+NTSSI ++ I KRK+K G+HFFNP P+M+L+E++ S + S++T +
Sbjct: 106 ITPSHTFLASNTSSIPISTIAEVTKRKEKIIGMHFFNPPPIMKLVEIVPSKYTSDETIEV 165
Query: 184 MMEWGKSVGKTCITCK-DTPGFV 249
++ K + K + K + PGFV
Sbjct: 166 TIDLAKKMNKIPVKLKVEVPGFV 188
Score = 46.8 bits (106), Expect = 3e-04
Identities = 23/58 (39%), Positives = 34/58 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVML 428
RI EA R E G+A+ E++D+A R G PMG EL+DY G+D+ + V++
Sbjct: 191 RIFLRLMQEACREVEDGEATIEEVDSAARNGLKLPMGIFELSDYVGIDVAVDLWNVIV 248
Score = 35.5 bits (78), Expect = 0.78
Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGL-DLKKSILAVMLK 431
R+++ E + + G +A+DIDT M G +P G +E+AD G+ ++ ++ + K
Sbjct: 302 RLISLAVNEGAWLIQNGIVNAKDIDTVMIYGFNFPKGLMEIADELGIRNIYNHLVDIYSK 361
Query: 432 ETGNPVFEPIGVLDXLV 482
G + P +++ L+
Sbjct: 362 --GYVAYRPNSLIEELI 376
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 80.6 bits (190), Expect = 2e-14
Identities = 37/81 (45%), Positives = 55/81 (67%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE TIL++NTSS+S+ I + R DK G+HFFNP PVM+L+E+I+ S++T+ A+
Sbjct: 108 PE-TILSSNTSSLSITEIATATNRPDKVIGMHFFNPAPVMKLIEIIRGMATSQETFDAVK 166
Query: 190 EWGKSVGKTCITCKDTPGFVV 252
E ++GK + + PGFVV
Sbjct: 167 EVSVAIGKDPVEVAEAPGFVV 187
Score = 73.3 bits (172), Expect = 3e-12
Identities = 41/94 (43%), Positives = 55/94 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA+ +Y G A+AEDID AM LGA +PMGPL L D GLD+ +I+ V+ E
Sbjct: 189 RILIPMINEAIGIYAEGIATAEDIDKAMMLGANHPMGPLALGDLIGLDVCLAIMDVLYTE 248
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
TG+ + +L V+ G RK G + Y+
Sbjct: 249 TGDTKYRAHSLLRKYVRAG-WLGRKTKKGFHDYS 281
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 80.6 bits (190), Expect = 2e-14
Identities = 34/82 (41%), Positives = 55/82 (67%), Gaps = 1/82 (1%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P+HTI ATNTSS+S+ + KR +KF G+HFFNP +++LLE++ + SE+T + +
Sbjct: 112 PDHTIFATNTSSLSITKLAEATKRPEKFIGMHFFNPPKILKLLEIVWGEKTSEETIRIVE 171
Query: 190 EWGKSVGKTCI-TCKDTPGFVV 252
++ + + + I KD PGF+V
Sbjct: 172 DFARKIDRIIIHVRKDVPGFIV 193
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD-LKKSILAVMLK 431
R++AP EA + E+G ASAE+ID A+ G YP G L +AD G+D + K + + K
Sbjct: 308 RLVAPAVNEAAWLIEKGVASAEEIDLAVLHGLNYPRGLLRMADDFGIDSIVKKLNELYEK 367
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G ++ VL +V+ G+ R G G Y Y
Sbjct: 368 YNGEERYKVNPVLQKMVEEGK-LGRTTGEGFYKY 400
Score = 43.6 bits (98), Expect = 0.003
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 3/94 (3%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTG---LDLKKSILAVM 425
RI S EA E G+ + E+ID+A++ G PMG EL D G +D+ +L
Sbjct: 195 RIFVTMSNEASWAVEMGEGTIEEIDSAVKYRLGLPMGLFELHDVLGGGSVDVSYHVLE-Y 253
Query: 426 LKETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
++T + P + + L K G +K G G Y
Sbjct: 254 YRQTLGESYRPSPLFERLFKAGH-YGKKTGKGFY 286
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 80.2 bits (189), Expect = 3e-14
Identities = 35/83 (42%), Positives = 50/83 (60%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P TILATNTSS++V AI S + ++ G HFFNPVP+M+++EVI +
Sbjct: 107 IVPAETILATNTSSLAVTAIASNCEHPERVAGFHFFNPVPLMKIVEVIPGISTKSSVVET 166
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ K +G + KDTPGF+V
Sbjct: 167 LTSLAKRMGHLGVVAKDTPGFIV 189
Score = 57.6 bits (133), Expect = 2e-07
Identities = 34/89 (38%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = +3
Query: 270 YSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL-AVMLKETGNP 446
Y EAL++ G AS EDID +R GAG+ MGP EL D TG+D+ ++ ++ + P
Sbjct: 196 YGTEALKILGEGVASFEDIDHILRDGAGFRMGPFELLDLTGIDVSHPVMESIYNQYYFEP 255
Query: 447 VFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ P L + G RK G G Y Y
Sbjct: 256 RYRP-HPLTRQMLTGNKLGRKVGEGFYHY 283
Score = 46.0 bits (104), Expect = 6e-04
Identities = 23/53 (43%), Positives = 30/53 (56%)
Frame = +3
Query: 300 RGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
+G AS EDID A++LG GYP GP+ D G IL + TG+P + P
Sbjct: 460 QGIASPEDIDNAVKLGLGYPYGPISWGDELGAQRILLILERIYGLTGDPRYRP 512
>UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 377
Score = 80.2 bits (189), Expect = 3e-14
Identities = 36/80 (45%), Positives = 51/80 (63%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E +LATNTSS+SV I + +R ++ G+HFFNP PVMRL+EV++ E+ E
Sbjct: 109 EEAVLATNTSSLSVAEISATTRRPERVVGMHFFNPAPVMRLVEVVRGPRSGEEALARAEE 168
Query: 193 WGKSVGKTCITCKDTPGFVV 252
+ +GKT + DTPGF+V
Sbjct: 169 AARRMGKTPVRVSDTPGFIV 188
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ P+ EALR+ E G++ A ID ++R G+ MGPLELAD G D+ ++ + +
Sbjct: 190 RVARPFYLEALRLAETGESPAR-IDASLR-ERGFRMGPLELADLIGQDVNLAVSESLFRR 247
Query: 435 -TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+P F P + + + G RK G G Y Y
Sbjct: 248 YYCHPRFRPSHLQRSMFEAG-LLGRKTGRGFYAY 280
Score = 42.7 bits (96), Expect = 0.005
Identities = 22/46 (47%), Positives = 27/46 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTG 392
R+++ EA E G ASA DID AM+LGA YP GP A+ G
Sbjct: 301 RVISCVVNEAFFALEEGVASAGDIDRAMQLGANYPKGPFAWAEELG 346
>UniRef50_Q47DJ5 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding;
n=1; Dechloromonas aromatica RCB|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dechloromonas aromatica (strain RCB)
Length = 705
Score = 79.8 bits (188), Expect = 4e-14
Identities = 36/83 (43%), Positives = 57/83 (68%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP+ T++A+NTSS+ ++ I ++R + F G+HFFNPVPVM L+EVIK S+
Sbjct: 409 VAPD-TVIASNTSSLRIDEIAMPLQRPENFVGMHFFNPVPVMALVEVIKGSRTSDVAVST 467
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+++ ++GKT I +D PGF+V
Sbjct: 468 AVDYAVTMGKTPIVVQDCPGFLV 490
Score = 34.3 bits (75), Expect = 1.8
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 2/95 (2%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL PY L + G ID M + G+PMGP L D G+D + V+
Sbjct: 492 RILTPYVRAFLDLVADG-VDFVRIDRVMEV-FGWPMGPAYLMDVVGIDTGCHVFDVI--S 547
Query: 435 TGNPVFEPIGVLDXL--VKRGEXXDRKPGXGIY*Y 533
G P PI + L + + +K G G Y Y
Sbjct: 548 AGYPAVMPIQENNALAVMVANQRYGQKNGIGFYRY 582
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 79.8 bits (188), Expect = 4e-14
Identities = 34/84 (40%), Positives = 55/84 (65%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
D+ P T+ TNTS++SV I SG + +++ G H+ NP P+M+L+EV H ++ ++
Sbjct: 112 DIVPPTTLFHTNTSTLSVTGIASGSRLRERVVGTHYCNPAPLMKLVEVANGRHTADWAHK 171
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
A +E+ S+GKT + KD PGF+V
Sbjct: 172 ATLEFLASLGKTSVVTKDRPGFIV 195
Score = 63.3 bits (147), Expect = 3e-09
Identities = 31/94 (32%), Positives = 51/94 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R L P+ + E G A+ E+IDTA+ G+PMGP L D G+D+ + + + ++
Sbjct: 197 RFLIPWENSCIEALEAGVATKEEIDTAVLGALGHPMGPFRLLDIVGMDIHQQVATRLYEQ 256
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+P F P +++ +V G+ RK G G Y Y+
Sbjct: 257 LRDPKFFPPPMVERMVAAGD-LGRKTGRGFYEYD 289
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 79.4 bits (187), Expect = 5e-14
Identities = 35/83 (42%), Positives = 50/83 (60%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P ++ATNTSS+SV AI + K ++ G HFFNPVP+MR++EVIK + A
Sbjct: 110 ILPRQAVIATNTSSLSVTAIAASAKYPERIAGFHFFNPVPLMRVVEVIKGALTGDAVVDA 169
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ E VG + DTPGF++
Sbjct: 170 LKELAVRVGHRPVNATDTPGFII 192
Score = 49.2 bits (112), Expect = 6e-05
Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Frame = +3
Query: 270 YSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPV 449
Y EAL M + G A IDT +R AG+ MGP EL D TGLD+ ++++E +
Sbjct: 199 YGTEALAMVKEGVADFATIDTILRDAAGFRMGPFELFDLTGLDVSH----LVMEEVYHQY 254
Query: 450 FEPIGVLDXLVKR----GEXXDRKPGXGIY*Y 533
+E L+ R RK G G Y Y
Sbjct: 255 YEESRYRPSLITRRRLEAGLLGRKTGRGFYDY 286
Score = 44.0 bits (99), Expect = 0.002
Identities = 23/66 (34%), Positives = 35/66 (53%)
Frame = +3
Query: 249 C*RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVML 428
C R+LA A + ++ +D+D A++LG GYP+GPL D G D+ IL +
Sbjct: 414 CQRVLAMIVNIAADIIQQNITCTDDLDAAVKLGLGYPLGPLAWGDRIGADVIVHILDSIH 473
Query: 429 KETGNP 446
T +P
Sbjct: 474 ARTFDP 479
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 79.4 bits (187), Expect = 5e-14
Identities = 32/77 (41%), Positives = 55/77 (71%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
+I+ATNTSSIS+ + ++ +KF G+HFFNP P+M L+E+++ + S++T + +++
Sbjct: 102 SIIATNTSSISITYLSKFVRNPEKFIGMHFFNPPPIMSLIEIVRGNSTSDETTKRIVDIS 161
Query: 199 KSVGKTCITCKDTPGFV 249
+S+GKT + D PGFV
Sbjct: 162 RSLGKTPVEVNDFPGFV 178
Score = 79.4 bits (187), Expect = 5e-14
Identities = 43/93 (46%), Positives = 56/93 (60%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L EA+ YE ASAE IDT M+LG +PMGPLEL+D+ GLD+ I+ V+ +
Sbjct: 181 RVLMAMLREAIIAYEENVASAEGIDTVMKLGMNHPMGPLELSDFIGLDVVYDIMNVLYND 240
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
TG+ F+P L LV G+ RK G G Y Y
Sbjct: 241 TGSERFKPPITLRNLVYAGK-LGRKTGEGFYKY 272
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 79.4 bits (187), Expect = 5e-14
Identities = 37/82 (45%), Positives = 52/82 (63%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P HTILA+NTSS+ + I + R + G+HF NPVPVM+L+EVI+ SE+T
Sbjct: 107 ICPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEETALD 166
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+M + +GKT + D PGFV
Sbjct: 167 VMALAEKMGKTAVEVNDFPGFV 188
Score = 66.9 bits (156), Expect = 3e-10
Identities = 38/93 (40%), Positives = 49/93 (52%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA+ G A E ID M+LG +PMGPL LAD+ GLD SI+ V+
Sbjct: 191 RVLLPMINEAIYCVYEGVAKPEAIDEVMKLGMNHPMGPLALADFIGLDTCLSIMEVLHSG 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G+ + P +L VK G +K G G Y Y
Sbjct: 251 LGDSKYRPCPLLRKYVKAG-WLGKKSGRGFYDY 282
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 79.0 bits (186), Expect = 6e-14
Identities = 42/85 (49%), Positives = 53/85 (62%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
EA+RM E A+A DID A+RLG G+PMGPLELAD GLD + + L M + +G+ +EP
Sbjct: 188 EAMRMVEEQVANAADIDKALRLGYGHPMGPLELADLVGLDARLNNLRSMFERSGDAAYEP 247
Query: 459 IGVLDXLVKRGEXXDRKPGXGIY*Y 533
VL LV G +K G G Y Y
Sbjct: 248 PAVLVDLVAAGH-LGKKSGRGFYDY 271
Score = 60.5 bits (140), Expect = 2e-08
Identities = 29/81 (35%), Positives = 44/81 (54%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP T+L +NTS++S++A+ + G+HFFNP M L+EV+ S+D
Sbjct: 97 APPGTLLVSNTSTMSISALAEACGGSSRVVGMHFFNPAHRMPLVEVVVGTRTSDDARDRA 156
Query: 187 MEWGKSVGKTCITCKDTPGFV 249
+ +GK I +D PGFV
Sbjct: 157 VALAVRLGKDPIVVRDLPGFV 177
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 78.6 bits (185), Expect = 8e-14
Identities = 36/84 (42%), Positives = 52/84 (61%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
D+ + +LATNTSS+SV A+G ++ +F GLHFFNP P++ L+EV+ +
Sbjct: 110 DVVGDDCLLATNTSSLSVTAVGGALRVPGRFVGLHFFNPAPLLPLVEVVSGFATDPASAT 169
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
E ++ GKT + C DTPGFVV
Sbjct: 170 RAYETARAWGKTPVACADTPGFVV 193
Score = 41.1 bits (92), Expect = 0.016
Identities = 16/25 (64%), Positives = 20/25 (80%)
Frame = +3
Query: 300 RGDASAEDIDTAMRLGAGYPMGPLE 374
+G A+ ED+DTAMRLG YP+GP E
Sbjct: 433 KGVAAPEDVDTAMRLGVNYPLGPFE 457
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 78.6 bits (185), Expect = 8e-14
Identities = 35/74 (47%), Positives = 46/74 (62%)
Frame = +1
Query: 25 LATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS 204
LA+NTSS+SVN + +KR F GLHFFNPVP L+EV+ + S D A W ++
Sbjct: 121 LASNTSSLSVNGLARELKRPGNFLGLHFFNPVPASTLIEVVLGEQTSPDLAAAAKRWVEA 180
Query: 205 VGKTCITCKDTPGF 246
+GKT + D PGF
Sbjct: 181 LGKTAVVVNDAPGF 194
Score = 66.1 bits (154), Expect = 5e-10
Identities = 41/91 (45%), Positives = 50/91 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ + EA+RM E G ASAEDID AM LG +P GPL D GLD++ I A L+
Sbjct: 198 RLGVAIALEAMRMVEEGVASAEDIDNAMVLGYKHPTGPLRTTDIVGLDVRLGI-AEYLQS 256
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
T F P +L V RGE RK G G +
Sbjct: 257 TLGERFAPPQILRDKVARGE-LGRKTGKGFF 286
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 78.2 bits (184), Expect = 1e-13
Identities = 40/94 (42%), Positives = 55/94 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI+ P EA+++ E G ASAEDID A+ LG YPMGP L DY G+D+ ++ +E
Sbjct: 192 RIMIPQFIEAIKLLEEGVASAEDIDKAVTLGLNYPMGPFTLQDYAGVDIGLHVMEYFQQE 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+P F P +L LV+ G +K G G Y Y+
Sbjct: 252 FNDPRFTPPLLLKQLVRAGR-LGKKVGAGFYDYD 284
Score = 75.4 bits (177), Expect = 8e-13
Identities = 34/79 (43%), Positives = 53/79 (67%), Gaps = 1/79 (1%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
TI+ATNTSS+S+ I + R D+ G+HFFNP +M+L+EV++ S+DT + + ++
Sbjct: 112 TIIATNTSSMSITEIAAATNRPDRVVGMHFFNPAQLMKLVEVVRGYQTSDDTVETVKQFA 171
Query: 199 KSVGKTCITC-KDTPGFVV 252
+ + K I KDTPGF+V
Sbjct: 172 RQLKKEPIEVKKDTPGFIV 190
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 78.2 bits (184), Expect = 1e-13
Identities = 31/78 (39%), Positives = 54/78 (69%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E+ I+A+NTS I++ I +K+KD+ G+H+FNP +M+L+EV+++ SEDT +++
Sbjct: 113 ENAIIASNTSGITIAEIAQDLKKKDRAIGMHWFNPAGIMKLIEVVRAKMTSEDTISTVVD 172
Query: 193 WGKSVGKTCITCKDTPGF 246
+ + +GKT + D PGF
Sbjct: 173 FSRRIGKTPVVVADVPGF 190
Score = 59.7 bits (138), Expect = 4e-08
Identities = 33/89 (37%), Positives = 45/89 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R + + A+R YE A+ DIDT +L G+PMGP EL + G+D I + +E
Sbjct: 194 RFIEGWLLAAIRSYEANIATKADIDTMAKLAFGFPMGPFELMNIIGIDTVYHIAEYLREE 253
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXG 521
TG+P F P L +V G D K G
Sbjct: 254 TGDPQFIPPVSLKQMVINGYLGDPKVKYG 282
>UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=42; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Salmonella typhimurium
Length = 729
Score = 78.2 bits (184), Expect = 1e-13
Identities = 35/81 (43%), Positives = 53/81 (65%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE T+LA+NTS+I + + S ++R + F G+HFFNPV M L+E+I+ + S++T ++
Sbjct: 420 PE-TVLASNTSTIPIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVV 478
Query: 190 EWGKSVGKTCITCKDTPGFVV 252
W +GKT I D PGF V
Sbjct: 479 AWASKMGKTPIVVNDCPGFFV 499
Score = 36.7 bits (81), Expect = 0.34
Identities = 21/57 (36%), Positives = 27/57 (47%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVM 425
R+L PY A ++ G A +D M G+PMGP L D G+D AVM
Sbjct: 501 RVLFPYFAGFSQLLRDG-ADFRKVDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVM 556
>UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Bdellovibrio bacteriovorus|Rep: Fatty oxidation
complex, alpha subunit - Bdellovibrio bacteriovorus
Length = 717
Score = 77.8 bits (183), Expect = 1e-13
Identities = 36/77 (46%), Positives = 50/77 (64%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I+ATNTSS+SV + G R + F G+HFFNPV M L+EVI+ + S++T + E K
Sbjct: 428 IIATNTSSLSVTEMAKGHPRPEYFAGMHFFNPVNKMPLIEVIRGEKTSDETIATIYELSK 487
Query: 202 SVGKTCITCKDTPGFVV 252
+GK + KD PGF+V
Sbjct: 488 KMGKMPVVVKDGPGFLV 504
Score = 48.8 bits (111), Expect = 8e-05
Identities = 33/94 (35%), Positives = 44/94 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L PY EA + + G S E +D G PMGP EL D GLD+ +L + K
Sbjct: 506 RLLLPYMGEAAFLLQEG-MSIEFVDKVYVKEFGMPMGPFELMDEVGLDVCLKVLKIFKKA 564
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G + E ++ L G RK G G Y Y+
Sbjct: 565 FGERI-ELAPCMEALGNSGR-LGRKNGKGFYTYS 596
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/93 (49%), Positives = 54/93 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LA + E +RMYE G ASAEDID A+RLG YPMGPLELAD GLD + M +
Sbjct: 191 RALAAHMIECIRMYEEGVASAEDIDKAVRLGLNYPMGPLELADMVGLDTLLFVSENMTEA 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G+ F +L LV+ G RK G G Y Y
Sbjct: 251 YGDR-FRAPQLLRKLVEAGH-LGRKTGKGFYTY 281
Score = 77.4 bits (182), Expect = 2e-13
Identities = 35/82 (42%), Positives = 50/82 (60%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
LA ILATNTS +SV A+ + R + G+H+FNP PVM+L+E++K + S+DT A
Sbjct: 107 LAKPDAILATNTSELSVTALAAATNRPENVIGMHWFNPAPVMKLIEIVKGETTSDDTVDA 166
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+ +GK + KD GFV
Sbjct: 167 IRRLSVELGKETVVVKDRQGFV 188
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 77.8 bits (183), Expect = 1e-13
Identities = 35/83 (42%), Positives = 50/83 (60%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP H ILATNTSS+SV+ + S +K ++ G HFFNPV ++ LLE+++ + E
Sbjct: 444 VAPAHAILATNTSSLSVSEMASKLKHPERVVGFHFFNPVAILPLLEIVRGEQTDEAALAT 503
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
K + KT + KD P FVV
Sbjct: 504 AFGVAKKLKKTAVLVKDAPAFVV 526
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 77.8 bits (183), Expect = 1e-13
Identities = 37/83 (44%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
APE+ I ATNTSS+S+ + +R ++F G+HFFNP M+L+EVI H +DT +A+
Sbjct: 127 APENAIFATNTSSLSITELSEVTERPEQFCGMHFFNPPVRMQLVEVISGAHSGDDTLEAI 186
Query: 187 MEWGKSVGKTCITC-KDTPGFVV 252
+ GKT + KD+PGF+V
Sbjct: 187 EALAEDFGKTPVRVRKDSPGFIV 209
Score = 49.6 bits (113), Expect = 4e-05
Identities = 30/93 (32%), Positives = 45/93 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA + A+ ++D+ + G PMG EL+D G D+ +L M +
Sbjct: 211 RILVPLMNEAAWLVHDDAATIAEVDSTTKFDMGLPMGSFELSDQVGNDVGLHVLEYMHEV 270
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G P + P +L+ V+ E +K G G Y Y
Sbjct: 271 LGEP-YAPCPLLEEKVE-NEELGKKTGKGFYDY 301
Score = 46.8 bits (106), Expect = 3e-04
Identities = 24/62 (38%), Positives = 36/62 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R++A + E ++ E A DID A++LG G+P GP ++AD TGL+ L +E
Sbjct: 320 RLVAVMANEVGKLVENDVAPVADIDQAVQLGGGFPDGPAKIADKTGLETLIDTLEETHEE 379
Query: 435 TG 440
TG
Sbjct: 380 TG 381
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 77.8 bits (183), Expect = 1e-13
Identities = 37/85 (43%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+ APE + TNTSS+S+ + R ++F G+HFFNP M L+EVI H SEDT +
Sbjct: 123 EYAPEEAVFVTNTSSLSITELSEVTDRPERFCGMHFFNPPVRMDLVEVISGKHTSEDTLE 182
Query: 181 AMMEWGKSVGKTCITC-KDTPGFVV 252
+ +S+GKT + KD+PGF+V
Sbjct: 183 LIEGLAESMGKTPVRVRKDSPGFIV 207
Score = 57.6 bits (133), Expect = 2e-07
Identities = 34/93 (36%), Positives = 47/93 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA + E GDA+ E +D+ + G PMG ELAD G+D+ +L M +
Sbjct: 209 RILVPLMNEAAWIVESGDATIETVDSTTKFDMGLPMGSFELADQVGIDVGYHVLEYMHEV 268
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G + P +L V+ E +K G G Y Y
Sbjct: 269 LGE-AYRPCPLLVEKVE-AEELGKKTGSGFYDY 299
Score = 44.8 bits (101), Expect = 0.001
Identities = 28/79 (35%), Positives = 39/79 (49%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+LA + E + A A ID A+ LGAG+P GP +LAD GL +L + +E
Sbjct: 318 RLLAVMANEVAGLAGNDVADAPAIDRAVMLGAGFPDGPAKLADSEGLAELVDVLDDLHEE 377
Query: 435 TGNPVFEPIGVLDXLVKRG 491
TG +E L + G
Sbjct: 378 TGEKRYEATDFLREAAEAG 396
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 77.4 bits (182), Expect = 2e-13
Identities = 40/94 (42%), Positives = 57/94 (60%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA + G ASAE+ID M+LGA +P+GPL LAD GLD+ +++ V +K+
Sbjct: 191 RILVPMINEAFFVLAEGIASAEEIDAGMKLGANHPIGPLALADLVGLDVCLAVMDVFVKD 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+P + +L +V G RK G G+Y Y+
Sbjct: 251 FGDPKYRACPLLREMVTAGR-LGRKTGRGVYDYS 283
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/83 (42%), Positives = 54/83 (65%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A I+ATNTSSIS+ A+ + + +F G+HFFNPVP+M L+E+I+ S+ T A
Sbjct: 107 VARAEAIIATNTSSISITALAAPLADPARFVGMHFFNPVPLMPLVEIIRGLQTSDATASA 166
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ E + K+ I +++PGFVV
Sbjct: 167 VRELTERFDKSPIGVRNSPGFVV 189
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 77.0 bits (181), Expect = 3e-13
Identities = 34/83 (40%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
APE A+NTS++ + I R ++F G+HFFNP +M+L+EVI + S++T +
Sbjct: 96 APEGAAFASNTSTLPITEIAQATSRPERFIGIHFFNPPQLMKLVEVIPGEGTSDETTRMT 155
Query: 187 MEWGKSVGKTCITC-KDTPGFVV 252
+E+ +S+GK + C KD PGF+V
Sbjct: 156 LEYVESLGKQAVLCRKDVPGFIV 178
Score = 56.0 bits (129), Expect = 5e-07
Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD-LKKSILAVMLK 431
R+ P EA +R AS E ID+A++ G G+PMG ELAD+TG+D + K+ + + +
Sbjct: 180 RLFIPMVHEACHAMDRTGASMEQIDSAVKFGLGFPMGIFELADFTGMDVIHKATVEMHQR 239
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+ G V P +++ + + +K G G Y Y+
Sbjct: 240 DKG--VVNPHPLVEKMFNE-KKLGKKSGEGYYKYS 271
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 76.6 bits (180), Expect = 3e-13
Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
A E ILA+NTSS+ + I + R +K G+HFFNP +M L+EV+K + SE+T A
Sbjct: 119 AKETAILASNTSSLPITEIAAATSRPEKVVGMHFFNPPVLMPLVEVVKGEKTSEETVAAT 178
Query: 187 MEWGKSVGK-TCITCKDTPGFVV 252
++ K +GK T + KD PGF+V
Sbjct: 179 VDLAKKMGKQTVVVKKDVPGFIV 201
Score = 51.2 bits (117), Expect = 1e-05
Identities = 32/85 (37%), Positives = 43/85 (50%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
EA + A+ EDID A++LG G+P G E AD GLD L + ++ G EP
Sbjct: 322 EAAWLLREDVATREDIDKAVKLGLGWPKGVFEYADEFGLDRVVEALERIKRDFGVDHAEP 381
Query: 459 IGVLDXLVKRGEXXDRKPGXGIY*Y 533
+L +V+ G RK G G Y Y
Sbjct: 382 DPLLKKMVEEGR-IGRKAGKGFYEY 405
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/93 (31%), Positives = 40/93 (43%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL A + ERG + +D + G PMG ELADY+G+D+ + M +
Sbjct: 203 RILGRLMESACLLVERGGYTVVQVDATAKYLLGLPMGVFELADYSGIDVFYYVFEAMSRR 262
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ + K GE K G GIY Y
Sbjct: 263 GFRSA--KCSIFEEKFKAGE-YGVKAGKGIYSY 292
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 75.8 bits (178), Expect = 6e-13
Identities = 43/81 (53%), Positives = 54/81 (66%), Gaps = 4/81 (4%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIK---SDH-ISEDTYQAMM 189
ILA+NTSSIS+ AI S +K ++F GLHFFNP PVM L+EVI SD I++ Y +
Sbjct: 124 ILASNTSSISITAIASCLKYPERFLGLHFFNPAPVMPLVEVISGLASDQLIAKQLYDTCL 183
Query: 190 EWGKSVGKTCITCKDTPGFVV 252
WGK+ KT K TPGF+V
Sbjct: 184 LWGKTPVKT----KSTPGFIV 200
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSI-LAVMLK 431
R+ P+ AEALR+YE A + ID M+ + MGP EL D G D+ ++ L+V
Sbjct: 202 RVARPFYAEALRIYEEQGAGIQQIDRLMKTAGQFRMGPFELMDLIGHDVNYAVTLSVFNA 261
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+P F+P LV+ G +K G Y Y+
Sbjct: 262 YYQDPKFKPSLTQKSLVEAG-FLGKKAARGFYTYD 295
Score = 45.6 bits (103), Expect = 7e-04
Identities = 27/80 (33%), Positives = 38/80 (47%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LA + EA + +G ASA+DID AM G YP GPL G+D +L+ +
Sbjct: 463 RTLAMLTNEAAQTCMQGIASAKDIDIAMCYGVNYPQGPLAWGQRVGVDYVFQVLSHLQAH 522
Query: 435 TGNPVFEPIGVLDXLVKRGE 494
G + ++ L GE
Sbjct: 523 YGEERYRASSLIKRLSLTGE 542
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 75.8 bits (178), Expect = 6e-13
Identities = 30/78 (38%), Positives = 48/78 (61%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+ A+NTSS+S+ AI ++ + GLHFFNP P+M+L+E++ S +T +
Sbjct: 116 TLFASNTSSLSITAIAGALQHPQRLAGLHFFNPAPLMKLVEIVSGLDTSTETVATLQRLT 175
Query: 199 KSVGKTCITCKDTPGFVV 252
+ GK + C+ TPGF+V
Sbjct: 176 RQWGKQSVLCRSTPGFIV 193
Score = 55.2 bits (127), Expect = 9e-07
Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL-AVMLK 431
R+ P+ AEALR E A A +D +R G+ MGPL+L D G D+ ++ +V
Sbjct: 195 RVARPFYAEALRALEEQVADAATLDAVIRDAGGFVMGPLQLTDMIGQDINYAVTESVFQA 254
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+P F P V LV G RK G G Y Y
Sbjct: 255 FFQDPRFTPSLVQQELVAAGR-LGRKSGRGFYRY 287
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/72 (40%), Positives = 37/72 (51%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LA + EAL + +G ASAED D AMR G YP GPLE G + L +
Sbjct: 423 RTLAMLANEALDVVNKGVASAEDTDHAMRYGVNYPRGPLEWGTALGWRHILTTLENLQLY 482
Query: 435 TGNPVFEPIGVL 470
G P + P+ +L
Sbjct: 483 YGEPRYRPMPLL 494
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 75.8 bits (178), Expect = 6e-13
Identities = 35/83 (42%), Positives = 52/83 (62%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L E T+LA+NTS+I ++ + +KR + F G+HFFNPV M L+E+I+ S+ T A
Sbjct: 417 LIGEDTVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAA 476
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
++ + +GKT I D PGF V
Sbjct: 477 VVAYATQMGKTPIVVNDCPGFFV 499
Score = 37.1 bits (82), Expect = 0.26
Identities = 22/57 (38%), Positives = 25/57 (43%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVM 425
R+L PY A M R ID M G+PMGP L D G+D AVM
Sbjct: 501 RVLFPYLA-GFGMLVRDGGDFHQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVM 556
>UniRef50_Q64428 Cluster: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) [Includes: Long-chain
enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-
hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]; n=43;
Bilateria|Rep: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) [Includes: Long-chain
enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-
hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] - Rattus
norvegicus (Rat)
Length = 763
Score = 75.8 bits (178), Expect = 6e-13
Identities = 35/81 (43%), Positives = 52/81 (64%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ PEH I A+NTS++ +N I + +R +K G+H+F+PV M+LLE+I +D S+DT +
Sbjct: 465 VTPEHCIFASNTSALPINQIAAVSQRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTAS 524
Query: 184 MMEWGKSVGKTCITCKDTPGF 246
+ G GK I KD PGF
Sbjct: 525 AVAVGLKQGKVIIVVKDGPGF 545
Score = 42.3 bits (95), Expect = 0.007
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LAP +E +R+ + G + +D A+ G G+P+G LAD G+D+ + + + K
Sbjct: 549 RCLAPMMSEVIRILQEG-VDPKKLD-ALTTGFGFPVGAATLADEVGIDVAQHVAEDLGKA 606
Query: 435 TGNPV-FEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G + +L +V +G RK G G Y Y
Sbjct: 607 FGERFGGGSVELLKLMVSKG-FLGRKSGKGFYIY 639
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 74.9 bits (176), Expect = 1e-12
Identities = 43/93 (46%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL EA+R+YE G A E IDTA R GYPMGP EL D TG+D+ E
Sbjct: 193 RILNAVRDEAIRLYEGGYAGVEAIDTACRTALGYPMGPFELMDLTGIDIGYLTKQARYAE 252
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
TG+P P + LV+RG RK G G Y Y
Sbjct: 253 TGDPADLPSRSVTELVERGH-LGRKTGRGWYTY 284
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P TILA+N+SS + + + R D+ LHFFNP VM +EV+ S T +
Sbjct: 108 LCPPATILASNSSSFVPSRLAAATGRADRVCNLHFFNPALVMACVEVVPGPETSGQTVAS 167
Query: 184 MMEWGKSVGKTCITC-KDTPGFV 249
++ +S+GK + K+ PGFV
Sbjct: 168 CVDLVESLGKVPVVLEKEIPGFV 190
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 74.9 bits (176), Expect = 1e-12
Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
LA I +NTS++ + + R +KF GLHFFNP +MRL+EVI+ + S++
Sbjct: 120 LAKPDCIFTSNTSTMRITMLADFTSRPEKFAGLHFFNPPVLMRLVEVIRGEKTSDEVMDL 179
Query: 184 MMEWGKSVGKTCITC-KDTPGFVV 252
++E+ KS+GKT + KD PGF+V
Sbjct: 180 LVEFVKSIGKTPVRVEKDVPGFIV 203
Score = 61.3 bits (142), Expect = 1e-08
Identities = 35/91 (38%), Positives = 52/91 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ AP S + + E+G A+ E++D +R G PMGP EL DYTG+D+ + L +
Sbjct: 205 RVQAPASVLLMAILEKGIATPEEVDATVRR-LGLPMGPFELVDYTGVDILYNALK-YYAQ 262
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
T +P +EP L+ +VK + RK G G Y
Sbjct: 263 TISPDYEPPKFLEEMVKANK-LGRKTGQGFY 292
Score = 54.8 bits (126), Expect = 1e-06
Identities = 30/77 (38%), Positives = 44/77 (57%), Gaps = 5/77 (6%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
EA+++ E G A+ +DIDTA++LG P GP ELA G + L + K+ G +FEP
Sbjct: 322 EAVKLVEMGVATPQDIDTAIKLGLNRPFGPFELAKQFGAEQIAKRLEELAKQFGKKIFEP 381
Query: 459 I-----GVLDXLVKRGE 494
G L+ L+K G+
Sbjct: 382 AKTLKEGKLEELLKAGK 398
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 74.1 bits (174), Expect = 2e-12
Identities = 34/76 (44%), Positives = 48/76 (63%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I A +TS+IS+ IGS KR + G+HF NPVP+ ++EVI+ H S +T A +
Sbjct: 123 IFAADTSAISITRIGSVTKRPSQVVGMHFMNPVPLKPMVEVIRGFHTSPETLGAAKRFLA 182
Query: 202 SVGKTCITCKDTPGFV 249
+GKTC+ +D PGFV
Sbjct: 183 EMGKTCVVVEDAPGFV 198
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/93 (32%), Positives = 44/93 (47%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L EA+ + + ASA D+D + + MGPLE AD GLD + V+ +
Sbjct: 201 RVLMLTINEAIFLVQDQVASAADVDRIFKGCFEHKMGPLETADLIGLDTILYSIEVLYES 260
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ + P +L +V G RK G G Y Y
Sbjct: 261 FNDDKYRPCPLLKKMVDAG-LHGRKSGRGFYTY 292
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 73.7 bits (173), Expect = 2e-12
Identities = 35/81 (43%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE +LATNTS +S+ I S K ++ G+HFFNP VMRL+E+I+ S++ Q +
Sbjct: 111 PE-VMLATNTSQLSITTIASSAKHPERVVGMHFFNPPVVMRLVEIIRGTMTSDEMLQRAI 169
Query: 190 EWGKSVGKTCITC-KDTPGFV 249
++ +GK I C +DTPGF+
Sbjct: 170 DFSDQLGKENIVCQRDTPGFI 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/93 (39%), Positives = 47/93 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R + E +R++E G AS ED+D AMRL +PMG EL DY GLD+ A L+E
Sbjct: 193 RAIMALRLECIRIFEEGIASKEDLDKAMRLAFNHPMGQFELNDYNGLDIALQ-GARNLRE 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
F P L V G+ RK G G + Y
Sbjct: 252 AYGDRFAPPPSLVSRVAAGQ-LGRKTGAGWFEY 283
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 73.3 bits (172), Expect = 3e-12
Identities = 31/83 (37%), Positives = 51/83 (61%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L ++ +NTS+IS+N + ++R F G+HFFNPV M L+E+I+ ++ S++T A
Sbjct: 421 LLDNSAVITSNTSTISINRLAESLERPQNFCGMHFFNPVHAMPLVEIIRGENTSDETIAA 480
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ + +GK I D PGF+V
Sbjct: 481 VCAYALGLGKKPIVVNDCPGFLV 503
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 73.3 bits (172), Expect = 3e-12
Identities = 34/83 (40%), Positives = 51/83 (61%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP+ +LA+NTSS+S+ A+ G+ R ++ GLHFFNP PVM+L+E++
Sbjct: 106 VAPD-AVLASNTSSLSMAAMAEGLARPERLLGLHFFNPAPVMKLVELVAHPGTGAAALDR 164
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
++ GKT I C D PGF+V
Sbjct: 165 ARRLTEAAGKTVIPCPDRPGFIV 187
Score = 48.8 bits (111), Expect = 8e-05
Identities = 33/90 (36%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL-AVMLK 431
R P+ EAL M E G ++AE ID AM+ AGYP+GP L D G D+ + ++
Sbjct: 189 RCARPFYGEALAMLEEGRSAAE-IDAAMQ-AAGYPLGPFGLIDLVGADINLAATESLAAA 246
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXG 521
G+P + L V G+ RK G G
Sbjct: 247 MEGHPRYHVFDALRRQVASGD-LGRKTGRG 275
Score = 33.1 bits (72), Expect = 4.2
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLEL 377
RI A EA + G + + IDTA++LG +P GP E+
Sbjct: 295 RIEAALVNEAGWLLAEGGTTQQGIDTALKLGLNFPRGPFEV 335
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 73.3 bits (172), Expect = 3e-12
Identities = 41/93 (44%), Positives = 52/93 (55%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L + EALR+ E G A+ EDIDTA RLG G+ MGPL D TGLD+ + +
Sbjct: 196 RLLVAFVNEALRLVESGIATPEDIDTACRLGFGHAMGPLATLDLTGLDVIAHAAEAIYQA 255
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T +P F P +L +V G RK G G Y Y
Sbjct: 256 TRDPKFAPPEILRRMVAAG-LLGRKSGRGFYTY 287
Score = 70.1 bits (164), Expect = 3e-11
Identities = 31/79 (39%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
Frame = +1
Query: 16 HTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
+ +LA+NT++I + I SG+ + G+HFF+PVPVM+L E+++ +DT +
Sbjct: 115 NVLLASNTTAIPITHIASGVSGPQRVVGMHFFSPVPVMQLCEIVRGLQTDDDTVARARRF 174
Query: 196 GKSVGKTCITC-KDTPGFV 249
+S+GKTCI +D GFV
Sbjct: 175 AESLGKTCIVVNRDVAGFV 193
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 72.9 bits (171), Expect = 4e-12
Identities = 41/92 (44%), Positives = 52/92 (56%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L Y A+RM E A+ EDID AMRLG G+PMGPL L D GLD IL M +++
Sbjct: 227 LLFGYLNNAVRMLEARYAAREDIDAAMRLGCGHPMGPLALLDLIGLDAAHEILNSMYRQS 286
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ + P +L LV+ G RK G G Y Y
Sbjct: 287 RDHLHAPAPLLSQLVRAG-LLGRKTGRGFYTY 317
Score = 69.7 bits (163), Expect = 4e-11
Identities = 31/84 (36%), Positives = 49/84 (58%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++ P T+ TNTSS+SV + +G R ++ G H+FNP PVMRL+EV+++
Sbjct: 141 EICPPATVFLTNTSSLSVTELAAGTARPERVLGTHWFNPAPVMRLVEVVRTVVTDPTVLA 200
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
++ VGKT + +D GF+V
Sbjct: 201 GVIGLVNDVGKTAVVAEDRAGFIV 224
Score = 68.1 bits (159), Expect = 1e-10
Identities = 34/88 (38%), Positives = 52/88 (59%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L PY +A++M + A+ ED+DTAM +G G+P+GP LAD GLD+ +I + +
Sbjct: 531 LLFPYLNDAVKMLQAHYATIEDVDTAMTVGCGHPLGPFALADVVGLDVTLAITRSLYAQF 590
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXG 521
P + P +L+ LV+ G RK G G
Sbjct: 591 REPGYAPAPLLEQLVRAG-FLGRKTGRG 617
Score = 56.4 bits (130), Expect = 4e-07
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A +LAT TSS+ V R G+H+FNP P M+L+EV+ + +D
Sbjct: 446 IAAPGAVLATTTSSLPVIECAMATSRPRDVIGMHWFNPAPAMKLIEVVPTVLTGDDVTAT 505
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
++ ++ G+ + C D GF+V
Sbjct: 506 VLALSRAAGRHPVLCADRAGFIV 528
>UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 288
Score = 72.9 bits (171), Expect = 4e-12
Identities = 33/77 (42%), Positives = 48/77 (62%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILA+NTSSI + + +F G+HFFNPVPVM L+E+I+ S+DT + +G+
Sbjct: 110 ILASNTSSIPITRLAQAAPDPARFIGVHFFNPVPVMGLIELIRGLATSDDTLATVEAYGR 169
Query: 202 SVGKTCITCKDTPGFVV 252
+GK + D PGF+V
Sbjct: 170 GLGKQIVHANDAPGFIV 186
Score = 69.7 bits (163), Expect = 4e-11
Identities = 37/91 (40%), Positives = 50/91 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA+ G A+ +DID RLG +PMGP+ LAD+ GLD I+ V+
Sbjct: 188 RVLMPLINEAIFALGEGVATMQDIDAGCRLGLNHPMGPITLADFIGLDTCLEIIRVLQSG 247
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
TG+P F P +L V+ G +K G G Y
Sbjct: 248 TGDPKFRPAPLLVQYVEAG-WVGKKAGRGFY 277
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 72.9 bits (171), Expect = 4e-12
Identities = 33/83 (39%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP +LA+NTS++S+ I + + + ++F G+HFFNPV M+L+EVI + S + +
Sbjct: 112 APAEALLASNTSTMSITEIATAVTKPERFLGMHFFNPVNRMKLVEVIFGEKTSAENVDLL 171
Query: 187 MEWGKSVGKTCI-TCKDTPGFVV 252
E K +GK + KD+PGF+V
Sbjct: 172 CELSKKIGKIPVKVLKDSPGFIV 194
Score = 49.6 bits (113), Expect = 4e-05
Identities = 34/91 (37%), Positives = 45/91 (49%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI AP A + + G ++ID M+ G PMGP ELADY G+D+ L E
Sbjct: 196 RIGAPNQALISAILDEGAIKPDEIDAIMKQ-MGMPMGPFELADYVGIDVFYHTLK-YYSE 253
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
T + F P L L+ +G+ K G GIY
Sbjct: 254 TLSKDFTPGKTLQALLDKGD-LGMKTGKGIY 283
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 72.5 bits (170), Expect = 6e-12
Identities = 39/94 (41%), Positives = 56/94 (59%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P+ E +R ++ G AS +DIDT M+LG PMGPLELAD+ GLD+ + +E
Sbjct: 195 RILMPWINEGVRAFDEGVASKDDIDTGMKLGTNVPMGPLELADHIGLDVCLDASETLHEE 254
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ ++P +L V G+ +K G G Y Y+
Sbjct: 255 LGDR-YKPAYLLQRKVDAGD-LGKKTGAGFYTYD 286
Score = 62.1 bits (144), Expect = 8e-09
Identities = 31/83 (37%), Positives = 42/83 (50%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
D PE +LATNTS++S+ I S R + GLHF NPVP+M +EV+ + D
Sbjct: 110 DALPEDVVLATNTSTLSITTIASVTDRASRVVGLHFMNPVPIMTGVEVVVGEKTDADVVA 169
Query: 181 AMMEWGKSVGKTCITCKDTPGFV 249
+ + K D PGFV
Sbjct: 170 FAHALAEDLDKETWESDDKPGFV 192
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 72.1 bits (169), Expect = 7e-12
Identities = 34/83 (40%), Positives = 51/83 (61%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P+ ++ATNTSS+SV A+ S ++ +F G HFFNPV V+ L+EV+++ E +
Sbjct: 424 LRPD-AVIATNTSSLSVTAMASVLEHPQRFVGFHFFNPVAVLPLVEVVRTPETDEASLAT 482
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
G + KTC+ +D P FVV
Sbjct: 483 AFAVGARLKKTCVLVQDAPAFVV 505
>UniRef50_P40939 Cluster: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) (78 kDa
gastrin-binding protein) [Includes: Long-chain enoyl-CoA
hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.211)]; n=29; Eumetazoa|Rep:
Trifunctional enzyme subunit alpha, mitochondrial
precursor (TP-alpha) (78 kDa gastrin-binding protein)
[Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17);
Long chain 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.211)] - Homo sapiens (Human)
Length = 763
Score = 72.1 bits (169), Expect = 7e-12
Identities = 33/79 (41%), Positives = 51/79 (64%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P+H I A+NTS++ ++ I + KR +K G+H+F+PV M+LLE+I ++ S+DT + +
Sbjct: 467 PDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAV 526
Query: 190 EWGKSVGKTCITCKDTPGF 246
G GK I KD PGF
Sbjct: 527 AVGLKQGKVIIVVKDGPGF 545
Score = 35.5 bits (78), Expect = 0.78
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LAP +E +R+ + G + +D+ + G+P+G L D G+D+ K + + K
Sbjct: 549 RCLAPMMSEVIRILQEG-VDPKKLDS-LTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKV 606
Query: 435 TGNPV--FEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G P +L +V +G RK G G Y Y
Sbjct: 607 FGERFGGGNP-ELLTQMVSKG-FLGRKSGKGFYIY 639
>UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Streptomyces avermitilis
Length = 272
Score = 71.7 bits (168), Expect = 1e-11
Identities = 44/111 (39%), Positives = 55/111 (49%)
Frame = +3
Query: 201 VCGQDLHHL*GHSRIRC*RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELA 380
V G+ + H S +L PY A+RM E G A A+DID AM LG +PMGPL LA
Sbjct: 163 VLGKQVVHAGDRSGFVVNALLIPYLLSAIRMCEAGFAGAQDIDKAMTLGCSHPMGPLALA 222
Query: 381 DYTGLDLKKSILAVMLKETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
D GLD +I + +E P +L +V G RK G G Y Y
Sbjct: 223 DLIGLDTVAAIGTALYEEFKEPTHAVPPLLSRMVD-GGLLGRKSGQGFYTY 272
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/82 (42%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE ILATNTS++ V + R + GLHFFNP PV+ L+EVI S + T +
Sbjct: 99 PE-AILATNTSALPVMRLARATDRPGQVLGLHFFNPAPVLPLVEVIGSLLTRDRTRRIAA 157
Query: 190 EWGKSV-GKTCITCKDTPGFVV 252
E+ +V GK + D GFVV
Sbjct: 158 EFATTVLGKQVVHAGDRSGFVV 179
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 71.7 bits (168), Expect = 1e-11
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTSSIS+ +I +G++ + GLHFFNP P+M L+EV+ + + Q +
Sbjct: 127 LLATNTSSISITSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQVLYATAA 186
Query: 202 SVGKTCITCKDTPGFVV 252
+ GK + K TPGF+V
Sbjct: 187 AWGKRPVMAKSTPGFIV 203
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ PY AEALR+ + ID MR G+ MGP EL D G D+ ++ + +
Sbjct: 205 RVARPYYAEALRVLNEQGGAPASIDAVMREAGGFRMGPFELMDLIGHDVNFAVTESVFRA 264
Query: 435 TGN-PVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
N P + P + LV G RK G G Y Y
Sbjct: 265 YFNDPRYTPSLIQQELVNAG-FLGRKSGRGFYSY 297
Score = 38.3 bits (85), Expect = 0.11
Identities = 21/62 (33%), Positives = 29/62 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R +A + EA +G S D+D AM G YP GPL AD G+ +L+ +
Sbjct: 435 RTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPCGPLAWADAIGIGRVHRVLSNLAAS 494
Query: 435 TG 440
G
Sbjct: 495 YG 496
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/92 (43%), Positives = 51/92 (55%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L PY A+RM E G A+ EDID A LG +PMGPL L D GLD KSI M +E
Sbjct: 197 LLVPYLLSAIRMVESGFATKEDIDKATVLGLAHPMGPLALTDLVGLDTVKSIADSMYEEF 256
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
P++ +L +V+ G +K G G Y Y
Sbjct: 257 KEPLYSAPPLLLRMVEAG-LVGKKSGAGFYEY 287
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/80 (36%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Frame = +1
Query: 16 HTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
+ +LA+NTSSI + +G K ++ G+HFFNPVPV+ L+E++ + S+ + +
Sbjct: 115 NAVLASNTSSIPIMKLGIATKSPERVIGMHFFNPVPVLPLVELVTTLKTSKSVSERAEAF 174
Query: 196 GKSV-GKTCITCKDTPGFVV 252
V GK + D GFVV
Sbjct: 175 ASDVLGKQVVRSADRSGFVV 194
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 71.7 bits (168), Expect = 1e-11
Identities = 30/78 (38%), Positives = 50/78 (64%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
TI+A+NTSS+S+ + + ++ + F GLHFFNP P+M L+EV++ E + + +
Sbjct: 114 TIVASNTSSLSITELAANFRKPENFLGLHFFNPAPMMSLVEVVRGLTTCESIIEKAVVFS 173
Query: 199 KSVGKTCITCKDTPGFVV 252
+S+GK + + PGFVV
Sbjct: 174 RSIGKEPVVVNEAPGFVV 191
Score = 64.9 bits (151), Expect = 1e-09
Identities = 37/93 (39%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA+ +Y G A + ID AM+LGA +P+GPL L+D G D+ SIL + E
Sbjct: 193 RMLIPMINEAIAIYSEGVADIKQIDKAMKLGANHPIGPLSLSDLIGNDVVLSILETLYLE 252
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T + + P +L V R RK G Y Y
Sbjct: 253 TRDNKYRPHTLLKKYV-RANKLGRKTKSGFYDY 284
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 71.7 bits (168), Expect = 1e-11
Identities = 31/85 (36%), Positives = 55/85 (64%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+L+P TILATNT+S+S++A+ +R ++ +HFFNP +M+L+E++ S +T +
Sbjct: 106 NLSPPETILATNTTSLSISAMAEATRRPERVVQMHFFNPPVIMKLVEIMPGKKTSRETVE 165
Query: 181 AMMEWGKSVGKTCITCK-DTPGFVV 252
A E+ + +GK + CK + P +V
Sbjct: 166 AAAEFARQLGKDPVVCKNEAPAGIV 190
Score = 63.7 bits (148), Expect = 3e-09
Identities = 34/93 (36%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L EA + G A +DID AM+LGA +PMGPLEL D GLD+ ++ + +
Sbjct: 192 RVLGQLLNEATWLVASGVADPQDIDKAMKLGANHPMGPLELIDLIGLDVHRAKMQTLSAF 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+P + +LD ++ G +K G G Y Y
Sbjct: 252 LNDPRYRHPDLLDRMIAEGR-LGKKVGKGFYTY 283
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 71.3 bits (167), Expect = 1e-11
Identities = 35/91 (38%), Positives = 52/91 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA R+ E G AS E++D G G+P+GP +LAD GLD+ +++ + +E
Sbjct: 191 RLLMPVLLEAARLVEEGVASREEVDLLATRGLGFPLGPFQLADLIGLDVALDVISYVHEE 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
G+P + P +L V+ G RK G G Y
Sbjct: 251 LGDPFYTPPRLLKNRVRSGR-LGRKTGEGFY 280
Score = 62.1 bits (144), Expect = 8e-09
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P +L TNTSSIS+ + S R ++ G HFF P P+ +EV++ + S++T +
Sbjct: 106 LLPPDALLLTNTSSISITELASATGRPERVCGAHFFTPPPLREAVEVVRGEQTSDETVER 165
Query: 184 MMEWGKSVGK-TCITCKDTPGF 246
+ S GK + KD PGF
Sbjct: 166 VRRLLSSFGKLPVVVRKDVPGF 187
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 71.3 bits (167), Expect = 1e-11
Identities = 33/77 (42%), Positives = 51/77 (66%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I+A+NTSS+S+ +I S +++ ++ G+HFFNP P+M+L+EVI + S+ + E K
Sbjct: 127 IIASNTSSLSIASIASSLQKPERCVGIHFFNPAPLMKLVEVIPAIQTSDAVLKISEETIK 186
Query: 202 SVGKTCITCKDTPGFVV 252
S K KDTPGF+V
Sbjct: 187 SWKKVVAVAKDTPGFIV 203
Score = 55.2 bits (127), Expect = 9e-07
Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL-AVMLK 431
R+ P+ EALR+YE G A ID AM+ G+ MGP EL D+ G D+ ++ V
Sbjct: 205 RVARPFYGEALRIYEEGMADFATIDFAMKSLGGFRMGPFELMDFIGNDVNYTVTETVFTA 264
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+P ++P + G RK G G Y Y+
Sbjct: 265 FYYDPRYKPAFTQKRFAEAG-YLGRKSGRGFYDYS 298
Score = 38.7 bits (86), Expect = 0.084
Identities = 38/133 (28%), Positives = 59/133 (44%)
Frame = +3
Query: 96 RPPFLQSSTSDATPGGYKKRSHFRGHLPGHDGVGQVCGQDLHHL*GHSRIRC*RILAPYS 275
+P F Q ++A GY R RG +G + +L + + R +L +
Sbjct: 272 KPAFTQKRFAEA---GYLGRKSGRGFYDYSEGTVRPEPSKDQNLLENIKNRIVVMLINEA 328
Query: 276 AEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFE 455
A+AL + ASA DID AM G YP G L AD G+D + L + +E G +
Sbjct: 329 ADALFL---NIASAIDIDNAMTKGVNYPKGLLTWADELGIDNCVNALDALYEEYGEDRYR 385
Query: 456 PIGVLDXLVKRGE 494
+L + + G+
Sbjct: 386 CSPLLRRMNREGK 398
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 70.9 bits (166), Expect = 2e-11
Identities = 42/94 (44%), Positives = 55/94 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ + EA+RM E G AS EDID AM LG +P+GPL+L D GLD++ I A L+
Sbjct: 203 RLGVAIALEAIRMVEEGVASPEDIDNAMVLGYKFPVGPLKLTDIVGLDVRLGI-AEYLES 261
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
T F P ++ +V RGE RK G G Y Y+
Sbjct: 262 TLGERFAPPQLMRDMVARGE-LGRKSGRGFYDYS 294
Score = 66.1 bits (154), Expect = 5e-10
Identities = 32/75 (42%), Positives = 45/75 (60%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
++ATNTSS+SV+ + + + GLH+FNPVP +L+EV+ +D E EW
Sbjct: 127 VIATNTSSLSVSDLALSVD--NPVIGLHYFNPVPASKLVEVVVADSTPEALVDLAREWVA 184
Query: 202 SVGKTCITCKDTPGF 246
+GKT I KD PGF
Sbjct: 185 GLGKTPIVVKDAPGF 199
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 70.9 bits (166), Expect = 2e-11
Identities = 40/94 (42%), Positives = 55/94 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ A EA+ M G ASA+DIDT++R+ +PMGPLEL D TG D + S+L L +
Sbjct: 193 RMSALMGNEAMYMLAEGVASADDIDTSLRMAFNHPMGPLELGDLTGWDTRLSVLQ-YLHQ 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
T F P ++ +VK G RK G G+Y Y+
Sbjct: 252 TMGEKFRPCPLIIKMVKAGR-YGRKVGRGVYEYD 284
Score = 69.7 bits (163), Expect = 4e-11
Identities = 29/82 (35%), Positives = 52/82 (63%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+L P I+A+NTS++S++ + + +R +F G+HFFNPV M+L+E+I+ ++ T +
Sbjct: 108 ELLPPEAIIASNTSALSISELAAATRRPTQFAGMHFFNPVHKMKLVELIRGIETTQATVE 167
Query: 181 AMMEWGKSVGKTCITCKDTPGF 246
+ ++GKT I + PGF
Sbjct: 168 RLKAVTAALGKTSIVVNEAPGF 189
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 70.9 bits (166), Expect = 2e-11
Identities = 38/91 (41%), Positives = 52/91 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ EA+RM + G A+ +DIDTAM LG +PMGP+EL D GLD++ IL + E
Sbjct: 190 RLGVSLGVEAMRMVQEGVATPQDIDTAMELGYNHPMGPIELGDVVGLDVRLDILEYLRDE 249
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
G F P +L V+ G+ +K G G Y
Sbjct: 250 LGER-FRPPQILKRKVRAGK-LGKKSGEGFY 278
Score = 64.5 bits (150), Expect = 1e-09
Identities = 29/76 (38%), Positives = 47/76 (61%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T++A+NTSS+S+ I S + ++ GLHFFNPV +M L+E++ ++ S +T E+
Sbjct: 111 TLIASNTSSLSLTEIASVLDYPERAIGLHFFNPVHIMALVEIVVAEQTSAETIARAREFV 170
Query: 199 KSVGKTCITCKDTPGF 246
+ KT + D PGF
Sbjct: 171 NGIDKTPVEVADAPGF 186
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 70.5 bits (165), Expect = 2e-11
Identities = 33/77 (42%), Positives = 46/77 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTSSISV AI +G++ + G+HFFNPVP MRL+EV+ + +
Sbjct: 122 VLATNTSSISVTAIANGLQHPARLVGMHFFNPVPQMRLVEVVSGLQTDPAVAALIFDLAG 181
Query: 202 SVGKTCITCKDTPGFVV 252
GK + + TPGF+V
Sbjct: 182 VWGKVAVHARSTPGFIV 198
Score = 32.3 bits (70), Expect = 7.3
Identities = 17/40 (42%), Positives = 19/40 (47%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLE 374
R LA EA G + E D AM+LG YP GP E
Sbjct: 430 RTLAMLINEAADAVLHGVCTPEGADAAMKLGVNYPAGPFE 469
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 70.5 bits (165), Expect = 2e-11
Identities = 32/80 (40%), Positives = 48/80 (60%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P TI+ATNTS + VN + G+K +F G+HFF+P +M+LLEV++SD S+ T A +
Sbjct: 392 PPETIIATNTSYLDVNRLSDGLKHPARFVGMHFFSPAHIMKLLEVVRSDRTSDGTLGAAL 451
Query: 190 EWGKSVGKTCITCKDTPGFV 249
+GK + GF+
Sbjct: 452 VLAHRLGKIPVLSGVCDGFI 471
Score = 46.0 bits (104), Expect = 6e-04
Identities = 32/93 (34%), Positives = 48/93 (51%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL+ Y A R+ G A+ ++ID AMR G G MGP D +GLD+ + +
Sbjct: 474 RILSSYRRAANRLLVEG-ANVDEIDAAMR-GFGMAMGPYAAQDMSGLDIAYANIRRKAVA 531
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
GN + +++ LV++ + RK G G Y Y
Sbjct: 532 EGN-CCGHVPLVERLVEKHKRLGRKSGAGWYDY 563
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 70.1 bits (164), Expect = 3e-11
Identities = 34/83 (40%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L I ATNTS +S+N I + R+D+F G HFF P V+ L+EV+++D SE T
Sbjct: 147 LCDPQAIFATNTSGLSINDIAQAVTRRDRFVGTHFFTPADVIPLVEVVRNDDTSEQTVAR 206
Query: 184 MMEWGKSVGK-TCITCKDTPGFV 249
+M ++ GK + KD PGF+
Sbjct: 207 VMGMLRAGGKRPVLVRKDIPGFI 229
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPM---GPLELADYTGLDLKKSILAVM 425
RI + EA+ + E+G ASAEDID ++ G + GPLE D G+D+ +I + +
Sbjct: 232 RIQHALAREAISLLEKGVASAEDIDEVVKWSLGIRLALSGPLEQRDMNGIDVHYAIASYL 291
Query: 426 LKETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
++ N P +L+ V+ GE K G G Y
Sbjct: 292 YQDLENRT-TPSELLENKVQAGE-LGAKSGQGFY 323
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 70.1 bits (164), Expect = 3e-11
Identities = 34/80 (42%), Positives = 48/80 (60%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P TILA+NTSSIS+ + S R +K G+HF NPVPVM+L+E+I S +T + +
Sbjct: 112 PPETILASNTSSISITTLASYTSRPEKVIGMHFMNPVPVMQLVEIINGLLTSSETTRRIE 171
Query: 190 EWGKSVGKTCITCKDTPGFV 249
E + K + D PGF+
Sbjct: 172 EISTQLNKIPVQTADYPGFI 191
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/79 (44%), Positives = 47/79 (59%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA+ + A +ID M+LG +PMGPL+LADY GLD+ +IL V+ K
Sbjct: 194 RILMPMINEAIYCVQERVAGIAEIDQIMKLGMAHPMGPLQLADYIGLDVCVNILNVLYKG 253
Query: 435 TGNPVFEPIGVLDXLVKRG 491
GNP + P +L +V G
Sbjct: 254 FGNPKYSPCPLLVNMVHAG 272
>UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 281
Score = 69.7 bits (163), Expect = 4e-11
Identities = 38/93 (40%), Positives = 53/93 (56%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA+ + G A+A+DID AM+ GA +PMGPL LAD G D+ SI+ + E
Sbjct: 190 RMLIPMINEAVSILAEGVATADDIDKAMKFGAHHPMGPLALADLIGNDVNLSIMETLYSE 249
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
TG+P + +L +V R RK G + Y
Sbjct: 250 TGDPKYRAHPLLRKMV-RANHLGRKTKKGFFEY 281
Score = 66.1 bits (154), Expect = 5e-10
Identities = 30/80 (37%), Positives = 46/80 (57%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ I+A+NTSS+S+ A S + GLHFFNP P+M L+E+I + Q +
Sbjct: 109 DSVIVASNTSSLSITAFASVLPNPQNVVGLHFFNPAPIMELVEIIVGHETAPAKIQLLQG 168
Query: 193 WGKSVGKTCITCKDTPGFVV 252
K++GK + ++ PGFVV
Sbjct: 169 LTKNLGKVPVVVQEAPGFVV 188
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 69.3 bits (162), Expect = 5e-11
Identities = 29/76 (38%), Positives = 47/76 (61%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T++A+NTSSIS+ +GS + + G+HFFNPVP L+E++++ + + EW
Sbjct: 114 TVIASNTSSISIAELGSALGDPARLIGMHFFNPVPASSLVEIVRAPATDAGVVEKVREWV 173
Query: 199 KSVGKTCITCKDTPGF 246
+GKT + D+PGF
Sbjct: 174 AQLGKTEVLVNDSPGF 189
Score = 64.1 bits (149), Expect = 2e-09
Identities = 37/83 (44%), Positives = 47/83 (56%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
EA+RM E G A AE ID AM LG +PMGPL D GLD++ +I + K G+ F P
Sbjct: 201 EAIRMLEEGVADAESIDRAMELGYRHPMGPLRSTDLVGLDVRLAIAEHLAKTLGDR-FAP 259
Query: 459 IGVLDXLVKRGEXXDRKPGXGIY 527
+L V +GE RK G G +
Sbjct: 260 PALLREKVAKGE-LGRKTGQGFF 281
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 69.3 bits (162), Expect = 5e-11
Identities = 36/84 (42%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKD--KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
A E + ATNTS I +NAI KD +F GLHFFNP +M+L+E+I + H E
Sbjct: 108 AKEDALFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKESIIL 167
Query: 181 AMMEWGKSV-GKTCITCKDTPGFV 249
+ + ++V GK I D PGFV
Sbjct: 168 DVKNFAQNVLGKGVIVVNDVPGFV 191
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 69.3 bits (162), Expect = 5e-11
Identities = 36/89 (40%), Positives = 51/89 (57%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
++PE ILATNTSS+SV A+ + + ++ G HFFNPV VM LLE++++ +
Sbjct: 454 VSPE-CILATNTSSLSVTAMAADLAHPERLVGFHFFNPVAVMPLLEIVRAPKTDDAVLAT 512
Query: 184 MMEWGKSVGKTCITCKDTPGFVVKGS*LR 270
E K + KT + KD FVV LR
Sbjct: 513 AFELAKGLKKTAVLVKDAAAFVVNRILLR 541
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 69.3 bits (162), Expect = 5e-11
Identities = 35/84 (41%), Positives = 47/84 (55%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
D A HTI A+NTSS+ ++ I G +R GLH+F+PV M L+EVI H S +T
Sbjct: 426 DHAAPHTIFASNTSSLPIHQIAEGARRPQLVVGLHYFSPVDKMPLVEVIPHAHTSAETVA 485
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
+ + GKT I D+ GF V
Sbjct: 486 TTVALARKQGKTAIVVGDSAGFYV 509
Score = 56.0 bits (129), Expect = 5e-07
Identities = 37/94 (39%), Positives = 50/94 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILAPY EA G+ E ID A+ + G+P+GPL L D G+D+ I+ V+ +E
Sbjct: 511 RILAPYINEAAYCLLEGEP-IESIDYAL-VRFGFPVGPLALLDEVGIDVATKIVPVLSEE 568
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ P D ++K G RK G G Y YN
Sbjct: 569 LGDRFTSP-PAFDAILKDGR-KGRKNGKGFYRYN 600
>UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 506
Score = 68.9 bits (161), Expect = 7e-11
Identities = 29/84 (34%), Positives = 52/84 (61%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++ TILA+NTS++S+ I SG R+D+ G HF P +M+L+E+ + + S+ +
Sbjct: 108 EICKPETILASNTSTLSITQIASGCGREDRVVGTHFCLPAQLMKLVEMSRGINTSDGVFS 167
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
A + W K+ G+ + +D PGF++
Sbjct: 168 AALAWTKAAGQLPVETQDKPGFIL 191
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R++ P +ALR+ + G A+AED+D RLG GYP GP+E GL ++ + +
Sbjct: 422 RLVRPKYNDALRLLDEGLATAEDMDMTCRLGLGYPEGPIERVTRGGLAYHCAVSGEIYRL 481
Query: 435 TGNPVFEP 458
TG P + P
Sbjct: 482 TGLPAYAP 489
Score = 53.6 bits (123), Expect = 3e-06
Identities = 25/47 (53%), Positives = 31/47 (65%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD 398
+L P++ + LR E G A+AEDID A+R G GY MGP L D GLD
Sbjct: 194 LLVPFNNDVLRAIEAGLATAEDIDLAIRSGLGYKMGPCTLLDLIGLD 240
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 68.9 bits (161), Expect = 7e-11
Identities = 31/77 (40%), Positives = 48/77 (62%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILA+NTSS+S+ A+ S + ++F GLHFFNPVP M+L+E+I S + + +
Sbjct: 116 ILASNTSSLSIEAMASAVPGPERFAGLHFFNPVPAMKLVELIPSSRTAPTVVDDLEALMR 175
Query: 202 SVGKTCITCKDTPGFVV 252
+ K + +D PGF+V
Sbjct: 176 AWKKLPVRVRDVPGFIV 192
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/50 (42%), Positives = 30/50 (60%)
Frame = +3
Query: 309 ASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
A A +DTAMR GA +P GP+E A G ++LA + TG+P++ P
Sbjct: 430 ADAAGVDTAMRYGANHPQGPIEWAGRFGTARLAAVLATIAAATGDPIYAP 479
Score = 41.5 bits (93), Expect = 0.012
Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILA-VMLK 431
R+ PY AE G A ID A+ G+ MGPL LAD G D+ ++ V
Sbjct: 194 RVARPYYAEGFAALGEGVDPAT-IDQALESAGGFRMGPLTLADLIGHDVNYTVACQVFDG 252
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G F P L G RK G G+Y Y
Sbjct: 253 YAGKTRFRPQPSQQALHDAGH-LGRKSGRGVYDY 285
>UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC
17978|Rep: PaaC - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 435
Score = 68.9 bits (161), Expect = 7e-11
Identities = 34/84 (40%), Positives = 48/84 (57%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++ TI A+NTSSISV AI +GI ++ GLHFFNP PVM+L+E+++
Sbjct: 34 EICSAQTIFASNTSSISVTAISAGIAHPERVVGLHFFNPAPVMKLVEIVQGLKTPNSLCL 93
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
A+ K + K TPGF+V
Sbjct: 94 ALKNLMLDWKKIPVLTKSTPGFIV 117
Score = 35.9 bits (79), Expect = 0.59
Identities = 19/47 (40%), Positives = 23/47 (48%)
Frame = +3
Query: 234 HSRIRC*RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLE 374
H + R +A EA G AS EDID AM+ G YP GP +
Sbjct: 335 HPALLTLRTIALLINEACEASLHGVASLEDIDNAMKYGVNYPKGPYQ 381
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 68.5 bits (160), Expect = 9e-11
Identities = 32/76 (42%), Positives = 47/76 (61%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTS++ V+AI + +R G HFF+P VMRLLEV++ + T A++ G+
Sbjct: 413 VLATNTSTLDVDAIAAATRRPQDVVGTHFFSPANVMRLLEVVRGARTAPRTLGAVLALGR 472
Query: 202 SVGKTCITCKDTPGFV 249
+GK C+T GFV
Sbjct: 473 RMGKVCVTVGVCDGFV 488
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 68.5 bits (160), Expect = 9e-11
Identities = 35/93 (37%), Positives = 52/93 (55%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL EA+++YE+G A +DID R +P+GP EL D +G+D+ ++ E
Sbjct: 197 RILGALQREAVQLYEQGIADYKDIDIICRKALNHPIGPFELMDLSGIDVGYYVMEQRYAE 256
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
TG+P+ +P ++ VK G RK G G Y Y
Sbjct: 257 TGDPLDKPAACIEEKVKEGH-LGRKTGKGWYEY 288
Score = 58.8 bits (136), Expect = 7e-08
Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++AP H I ATN+S+I + + + R +K +HFF P VM +EV+ S SE+T +
Sbjct: 111 EMAPPHAIFATNSSTIVNSLLANAADRPEKTVNMHFFFPPLVMDCVEVVMSSRTSEETAE 170
Query: 181 AMMEWGKSVGKTCITC-KDTPGFV 249
ME ++ +T + K+ GFV
Sbjct: 171 TAMEVCNAINRTAVLLKKEISGFV 194
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 68.5 bits (160), Expect = 9e-11
Identities = 30/80 (37%), Positives = 51/80 (63%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ ILA+NTS++ + + + + + ++F G+HFFNPV M+L+EVI+ S+ T + +
Sbjct: 424 DDAILASNTSTLPITQLAANLAKPERFVGIHFFNPVRKMKLVEVIRGAQTSDATVASAVA 483
Query: 193 WGKSVGKTCITCKDTPGFVV 252
+ K +GK I D PGF+V
Sbjct: 484 FAKRLGKFPIVVNDGPGFLV 503
Score = 37.9 bits (84), Expect = 0.15
Identities = 30/93 (32%), Positives = 41/93 (44%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L PY EAL + + G S E +D + G P+GP+ L D G+D M
Sbjct: 505 RLLFPYMNEALALLQEG-VSMERVDKCAKK-FGMPLGPITLYDMVGIDTAFYAGRTMYDA 562
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ +L LVK G +K G G Y Y
Sbjct: 563 FPDRTLAS-PILPALVKAGR-LGQKSGLGFYSY 593
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 68.1 bits (159), Expect = 1e-10
Identities = 33/81 (40%), Positives = 48/81 (59%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP ATNTS++S IGS KR ++ +HFFNPV M+L+E+I+ S++T Q
Sbjct: 108 APASCYFATNTSTMSPTEIGSFTKRPERVIAMHFFNPVHKMKLVEIIRGLETSDETAQVA 167
Query: 187 MEWGKSVGKTCITCKDTPGFV 249
E + +GK + + PGFV
Sbjct: 168 KEAAERMGKETVVVNEFPGFV 188
Score = 66.1 bits (154), Expect = 5e-10
Identities = 37/93 (39%), Positives = 52/93 (55%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI A EA M + G + E+ID A++LG +PMGP ELAD GLD + + L + ++
Sbjct: 191 RISALVGNEAFYMLQEGVGTPEEIDKAIKLGLNFPMGPFELADLVGLDTRLNNLKYLHEK 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G + P +L+ VK G RK G G+Y Y
Sbjct: 251 LGEK-YRPAPLLEQYVKAGR-LGRKTGRGVYDY 281
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 68.1 bits (159), Expect = 1e-10
Identities = 32/83 (38%), Positives = 52/83 (62%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L PE I+A++TSSIS+ + + R ++F G+HF NPVP+M L+E+I+ + T++A
Sbjct: 110 LKPE-AIVASDTSSISITRLAAATDRPERFIGIHFMNPVPLMELVELIRGIATDDATFEA 168
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
E+ +GK +D P F+V
Sbjct: 169 SKEFVAKLGKQVAVSEDFPAFIV 191
Score = 66.1 bits (154), Expect = 5e-10
Identities = 39/93 (41%), Positives = 51/93 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL P EA+ G + E ID AM+LGA +PMGPLELAD+ GLD SI+ V+ +
Sbjct: 193 RILLPMINEAIYTLYEGVGNVEAIDAAMKLGAHHPMGPLELADFIGLDTCLSIMQVLHEG 252
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ + P +L V+ G RK G Y Y
Sbjct: 253 LADSKYRPCPLLVKYVEAG-WLGRKTQRGFYDY 284
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 67.7 bits (158), Expect = 2e-10
Identities = 32/81 (39%), Positives = 52/81 (64%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
++PE TI+A+NTS++ ++++ + R D+F GLHFF+PV M LLE+I+ + S+ T A
Sbjct: 418 VSPE-TIIASNTSTLPISSLAGMVDRPDQFIGLHFFSPVDKMPLLEIIRGEQTSKSTVNA 476
Query: 184 MMEWGKSVGKTCITCKDTPGF 246
+ + + KT I D GF
Sbjct: 477 ALAFSHQITKTPIVVNDGRGF 497
Score = 32.7 bits (71), Expect = 5.5
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLK- 431
R+ ++ E + M G +A I+ A L AGYP+GPL ++D L L I K
Sbjct: 501 RVFKQFTYEGMAMLAEGVPAAA-IENAAWL-AGYPVGPLAVSDEVTLTLMDRIRTQTRKD 558
Query: 432 -ETGNPVFEP---IGVLDXLVKRGEXXDRKPGXGIY*Y 533
ET ++P V+D +++ + G G Y Y
Sbjct: 559 LETEGKTYQPHPGDAVIDRMLELNR-VSKAGGAGFYEY 595
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 67.7 bits (158), Expect = 2e-10
Identities = 40/93 (43%), Positives = 51/93 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L EA M + G A+AEDIDTAM+LGA +PMGPL LAD GLD+ + +
Sbjct: 192 RLLCVLINEAFGMLQDGIAAAEDIDTAMQLGAHHPMGPLALADMIGLDVILAATETLANG 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
N + +L V RG RK G G+Y Y
Sbjct: 252 IDNHKYAASPLLRDYVARGR-LGRKSGQGVYDY 283
Score = 67.3 bits (157), Expect = 2e-10
Identities = 30/80 (37%), Positives = 48/80 (60%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ ILA++TSS+S+ A+G+ +F G+HF NPVP+M L+E+I S T +
Sbjct: 111 KEAILASSTSSLSITALGAASGIPQRFIGMHFMNPVPLMELVELIAGSETSPRTIDIARQ 170
Query: 193 WGKSVGKTCITCKDTPGFVV 252
++GK + KD PGF++
Sbjct: 171 MVTALGKQSVCSKDQPGFII 190
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 67.3 bits (157), Expect = 2e-10
Identities = 36/93 (38%), Positives = 51/93 (54%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L PY A+ +YE+G A+ E ID A+ AG+PMGPL L D GLD+ ++ V+ E
Sbjct: 194 LLVPYLNHAVAVYEQGLATREQIDAAITSAAGFPMGPLTLMDLVGLDVLLDVMDVLWDEF 253
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
P + +L +V G RK G G Y Y+
Sbjct: 254 RRPRYAAAPLLRRMVAAG-LLGRKSGRGFYDYS 285
Score = 64.5 bits (150), Expect = 1e-09
Identities = 34/82 (41%), Positives = 45/82 (54%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P ILATNTSS+SV I + R K GLHFFNP PVMRL+E++ + +
Sbjct: 109 ILPPAAILATNTSSLSVTEIAALTSRPGKVIGLHFFNPAPVMRLVEIVTTVVTEPHVRET 168
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+ +GKT + D GFV
Sbjct: 169 ATQVVTRLGKTPVAVGDRAGFV 190
Score = 49.6 bits (113), Expect = 4e-05
Identities = 30/79 (37%), Positives = 42/79 (53%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L P+ +A RM G A+A+D+DTAMRLG GYP G + D G+ LA L
Sbjct: 316 LLVPHLNDAARMIGDGYATADDVDTAMRLGCGYPKGLAAMLDERGVKNVTETLA-ELAAA 374
Query: 438 GNPVFEPIGVLDXLVKRGE 494
G + +L L K+G+
Sbjct: 375 GLFTDDTAPLLTMLAKQGK 393
>UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Photobacterium profundum 3TCK|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Photobacterium profundum 3TCK
Length = 713
Score = 67.3 bits (157), Expect = 2e-10
Identities = 31/83 (37%), Positives = 52/83 (62%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
++P T LA+NTS++ ++ + +K+ + F G+HFFNPV M L+EVI+ + S+ T
Sbjct: 416 VSPNAT-LASNTSTLMISGLAQALKKPENFCGIHFFNPVHKMPLVEVIRGEQTSDQTITQ 474
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+++ +GKT I D GF+V
Sbjct: 475 AVKYVSQLGKTPIVVNDCAGFLV 497
Score = 33.9 bits (74), Expect = 2.4
Identities = 21/57 (36%), Positives = 25/57 (43%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVM 425
R L PY ++ G ID M G G+PMGP L D GLD + VM
Sbjct: 499 RCLTPYFHAFNQLVVDG-GDIPTIDKVMSKGFGWPMGPAYLLDVIGLDTAAHCIDVM 554
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 67.3 bits (157), Expect = 2e-10
Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 3/80 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+I+++NTS I + A+ G+ K F G HFFNPV M LLE+IK + SE+ + M
Sbjct: 124 SIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHLLEIIKGEETSEEVLRFMAA 183
Query: 193 WG-KSVGKTCITCKDTPGFV 249
+G K +GK + KDTP F+
Sbjct: 184 FGEKRLGKGIVWAKDTPNFI 203
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 67.3 bits (157), Expect = 2e-10
Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 1/78 (1%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I+A+NTSS+ + + ++ ++F G+HFFNP +M+L+EVI+ D+ SE+ ++ ++ K
Sbjct: 105 IIASNTSSLPITELSRAVRNPERFLGMHFFNPPVLMKLVEVIRGDNTSEERFREALDIVK 164
Query: 202 SVGKTCITC-KDTPGFVV 252
S+GK + KD GFVV
Sbjct: 165 SLGKYPLPVRKDVFGFVV 182
Score = 35.9 bits (79), Expect = 0.59
Identities = 26/69 (37%), Positives = 34/69 (49%)
Frame = +3
Query: 321 DIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEPIGVLDXLVKRGEXX 500
+ID G PMG + L DYTGLD+ I + + G P VL+ +VK G+
Sbjct: 204 EIDYVAIKELGMPMGLIMLLDYTGLDVNYDI-SKEAERRGFPF--KCDVLEGMVKSGK-L 259
Query: 501 DRKPGXGIY 527
RK G G Y
Sbjct: 260 GRKSGQGFY 268
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 66.9 bits (156), Expect = 3e-10
Identities = 32/77 (41%), Positives = 46/77 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTSS+SV +I + ++ G HFFNPVP+M+++EVI A++ K
Sbjct: 155 ILATNTSSLSVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAK 214
Query: 202 SVGKTCITCKDTPGFVV 252
+G I KD PGF++
Sbjct: 215 RMGHHGIRAKDMPGFII 231
Score = 51.6 bits (118), Expect = 1e-05
Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Frame = +3
Query: 270 YSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE-TGNP 446
Y EAL++ A DID +R AG+ MGPLEL D TGLD+ ++ + + P
Sbjct: 238 YGTEALKILGECVAPRGDIDRILRESAGFRMGPLELFDLTGLDVSHPVMESIYNQFYQEP 297
Query: 447 VFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ P L + G RK G G Y Y
Sbjct: 298 RYRP-SALTRQMLEGGYVGRKVGQGFYRY 325
Score = 40.7 bits (91), Expect = 0.021
Identities = 20/39 (51%), Positives = 26/39 (66%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPL 371
R LA A + ++G A+A+DID A+RLG GYP GPL
Sbjct: 460 RTLAAIVNLACDIAQQGIATADDIDQAVRLGLGYPQGPL 498
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 66.9 bits (156), Expect = 3e-10
Identities = 32/77 (41%), Positives = 46/77 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTSS+SV +I + ++ G HFFNPVP+M+++EVI A++ K
Sbjct: 115 ILATNTSSLSVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAK 174
Query: 202 SVGKTCITCKDTPGFVV 252
+G I KD PGF++
Sbjct: 175 RMGHHGIRAKDMPGFII 191
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/68 (44%), Positives = 40/68 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LA A + ++G A+A+DID A+RLG GYP GPL D G IL+ ML+
Sbjct: 420 RTLAAIVNLACDIAQQGIATADDIDQAVRLGLGYPQGPLAWGDALGASRILKILSRMLEL 479
Query: 435 TGNPVFEP 458
TG+P + P
Sbjct: 480 TGDPRYRP 487
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Frame = +3
Query: 270 YSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE-TGNP 446
Y EAL+++ A DID +R AG+ MGPLEL D TGLD+ ++ + + P
Sbjct: 198 YGTEALKIFGECVAPRGDIDRILRESAGFRMGPLELFDLTGLDVSHPVMESIYNQFYQEP 257
Query: 447 VFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ P L + G RK G G Y Y
Sbjct: 258 RYRP-SALTRQMLEGGYVGRKVGQGFYRY 285
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 66.9 bits (156), Expect = 3e-10
Identities = 38/94 (40%), Positives = 53/94 (56%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R++ P EA ++ G ASAEDIDTAMRLG P GPLE+AD GLD + + +E
Sbjct: 191 RLIVPLINEACQVLMEGVASAEDIDTAMRLGFEMPRGPLEIADRIGLDTVLVMAERLWRE 250
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ + P +L LV+ G + G G + Y+
Sbjct: 251 YGDLKYRPAPILKKLVRAGH-LGVETGEGFFKYD 283
Score = 59.3 bits (137), Expect = 6e-08
Identities = 25/76 (32%), Positives = 47/76 (61%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILA+NTS++S+ + S R DK G HF P+P R+++V++ S++T +M +
Sbjct: 113 ILASNTSTLSITEMASATNRPDKVIGCHFLQPIPRTRVVQVVRGLKTSDETVSQVMALME 172
Query: 202 SVGKTCITCKDTPGFV 249
+G+T + ++PG++
Sbjct: 173 RLGRTGVEVFESPGYI 188
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 66.9 bits (156), Expect = 3e-10
Identities = 31/80 (38%), Positives = 49/80 (61%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ ILA+NTSS+S+ + ++R + F G+HFFNPV M L+E+I + S+ T +++
Sbjct: 431 KQAILASNTSSLSITEMAVNLQRPENFIGMHFFNPVNRMPLVEIIPGEKTSQQTIVTLVK 490
Query: 193 WGKSVGKTCITCKDTPGFVV 252
K GKT I + GF+V
Sbjct: 491 LAKKAGKTPIVVANCAGFLV 510
Score = 37.5 bits (83), Expect = 0.19
Identities = 27/91 (29%), Positives = 42/91 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL + EA M + G E +D A+ G PMGP LAD G+D+ + V+ +
Sbjct: 512 RILISFLNEAALMLQEGGVVTE-MDHALE-AFGLPMGPFVLADEVGIDIGYHVAKVLEQA 569
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
G + + G+ + + +K G G Y
Sbjct: 570 YGERM-KVAGLFTQIFIDEKLLGKKSGVGFY 599
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 66.5 bits (155), Expect = 4e-10
Identities = 37/93 (39%), Positives = 51/93 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P A + + G ASAEDIDTAM+ GAG+PMGPLELAD G+D+ ++ V+ +
Sbjct: 224 RLLIPLINSASDLLDSGVASAEDIDTAMKKGAGFPMGPLELADMIGIDVVVDVMEVLERA 283
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G V+ ++ RK G Y Y
Sbjct: 284 YGERY--KTSVILRRMREANRLGRKTRIGFYKY 314
Score = 51.6 bits (118), Expect = 1e-05
Identities = 30/85 (35%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISED---TYQA 183
EH I+A+NTSS+S+ + S +KR + LHFFNP ++ L+EV+ S + S++ T +
Sbjct: 138 EHAIIASNTSSLSITEMSSRLKRPENALILHFFNPPYLLPLVEVVPSLYTSDEAKNTAVS 197
Query: 184 MMEWGKS--VGKTCITCKDTPGFVV 252
++ K+ G + K+ GF+V
Sbjct: 198 LISRMKNHREGMVPVMAKEREGFIV 222
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 65.7 bits (153), Expect = 6e-10
Identities = 37/93 (39%), Positives = 51/93 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI A EA M + G + E+ID A++LG YPMGP EL D GLD + + L + ++
Sbjct: 201 RISALVGNEAFYMLQEGLGTPEEIDKAIKLGLNYPMGPFELGDLVGLDARLNNLKYLHEK 260
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G + P +L+ VK G RK G G+Y Y
Sbjct: 261 LGEK-YRPAPLLEKYVKAGR-LGRKSGRGVYDY 291
Score = 58.8 bits (136), Expect = 7e-08
Identities = 31/83 (37%), Positives = 44/83 (53%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+ A E ATNTS++S I S R K +HFFNPV M L+E+++ S++T Q
Sbjct: 116 EYAQESCYFATNTSTMSPTEIASFTGRPKKVIAMHFFNPVHKMPLVEIVRGLETSDETTQ 175
Query: 181 AMMEWGKSVGKTCITCKDTPGFV 249
K +GK + + PGFV
Sbjct: 176 FAENAAKRMGKETVVINEFPGFV 198
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 65.7 bits (153), Expect = 6e-10
Identities = 37/83 (44%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP +LATN+SS+S+ I + +R + GLHFFNP M L+EVI +++T Q
Sbjct: 113 APADALLATNSSSLSITEIAAATERPESVLGLHFFNPPVKMDLVEVIYGKATTDETAQRG 172
Query: 187 MEWGKSVGKTCI-TCKDTPGFVV 252
E+ +S+GKT I KD GFVV
Sbjct: 173 YEFIESLGKTPIYVRKDVRGFVV 195
Score = 53.2 bits (122), Expect = 4e-06
Identities = 35/93 (37%), Positives = 46/93 (49%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L P+ +E M G+A+ D AM GYPMGP EL D TG+D+ + E
Sbjct: 198 VLGPFMSEPAWMVSAGEATIRQADAAMVHERGYPMGPFELGDLTGIDIGYHVRT----EA 253
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G PV PI + V+ G RK G G Y Y+
Sbjct: 254 GRPV-PPI--MAEKVENGN-LGRKTGEGYYDYD 282
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/94 (35%), Positives = 47/94 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ A + EA ++ A+AE IDT M+LGAG+P G AD GLD L + E
Sbjct: 301 RVEAVMANEAAKLVGDDVATAEAIDTGMQLGAGFPEGTCRRADDIGLDTILEKLRALSDE 360
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+ +EP L LV+ G + G G + Y+
Sbjct: 361 HSDDRYEPADYLVELVEAGH-TGTEAGRGFHEYD 393
>UniRef50_Q4REL3 Cluster: Chromosome 10 SCAF15123, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15123, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 768
Score = 65.3 bits (152), Expect = 8e-10
Identities = 30/73 (41%), Positives = 46/73 (63%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P H ILATNTS++ + I + KR +K G+H+F+PV M+LLE+I ++ S+DT +
Sbjct: 416 VVPPHCILATNTSALPIKDIAAASKRPEKVVGMHYFSPVDKMQLLEIITTEQTSKDTVAS 475
Query: 184 MMEWGKSVGKTCI 222
+ G GK I
Sbjct: 476 AVAVGLKQGKVII 488
Score = 36.3 bits (80), Expect = 0.45
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R LAP AEA+R+ + G + +D A+ G+P+G LAD G+D+ + + K
Sbjct: 528 RCLAPMLAEAVRLLQEG-VDPKKLD-ALTTSFGFPVGAATLADEVGIDVAAHVAEDLGKA 585
Query: 435 TGN 443
G+
Sbjct: 586 FGS 588
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 65.3 bits (152), Expect = 8e-10
Identities = 31/80 (38%), Positives = 49/80 (61%), Gaps = 3/80 (3%)
Frame = +1
Query: 22 ILATNTSSISVNAIG---SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
I+A+NTSS+ + +G S +RK +F G+HFF+P +M+L+EV+ + S +T +
Sbjct: 116 IIASNTSSLPITKLGACFSSAERKSRFVGMHFFSPAAIMKLVEVVNGEDTSAETVETACA 175
Query: 193 WGKSVGKTCITCKDTPGFVV 252
+ S+GK I D GFVV
Sbjct: 176 FCTSIGKEPIKVNDCAGFVV 195
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/94 (37%), Positives = 46/94 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL + EA+R+ E ASA DID A +LG G+P+GP L D +L I +
Sbjct: 197 RILGAINDEAIRLLEENVASAADIDKACQLGLGHPVGPFALMDQISNELNLKIARIFHGI 256
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ F P L V G RK G G + Y+
Sbjct: 257 YGDR-FLPRPALVRKVDAGH-FGRKTGKGWFDYS 288
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 65.3 bits (152), Expect = 8e-10
Identities = 31/80 (38%), Positives = 46/80 (57%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
EH +LATNTS+I + + G+KR + GLHFFNPV M L+EV++ S Q
Sbjct: 412 EHALLATNTSAIPLQTLAQGLKRPQQLLGLHFFNPVARMPLVEVVEGPQTSMQALQMGYR 471
Query: 193 WGKSVGKTCITCKDTPGFVV 252
+ ++ + + K PGF+V
Sbjct: 472 FVHAIQRLPLPVKSRPGFLV 491
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/93 (40%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L PY EA+RM + G ID A + G PMGPL LAD GLD+ K++ ++
Sbjct: 493 RVLMPYLMEAVRMVDEG-VDMRRIDKAA-MDFGMPMGPLALADAVGLDVCKAVARELVGS 550
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G V P +L+ LV G+ RK G G Y Y
Sbjct: 551 VGGGV--PQRLLE-LVSAGQ-LGRKSGAGFYRY 579
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 65.3 bits (152), Expect = 8e-10
Identities = 26/75 (34%), Positives = 44/75 (58%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
++ +NTSSIS+ + S + ++F G+HFFNP + +L+E++K E + +W
Sbjct: 113 VIGSNTSSISITKLSSAVSNPERFLGIHFFNPAQIQKLVELVKGLLSDEKLVNGIRDWFL 172
Query: 202 SVGKTCITCKDTPGF 246
+GK I D+PGF
Sbjct: 173 KLGKVPIVVNDSPGF 187
Score = 64.1 bits (149), Expect = 2e-09
Identities = 38/89 (42%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFEP 458
EAL M + G A+ +DID M LG GY MGP+E D GLD + I M + T +P + P
Sbjct: 199 EALLMVQEGVATPQDIDIGMMLGYGYSMGPIETGDLVGLDTRLRIYEAMFEATKDPKWAP 258
Query: 459 IGVLDXLVKRGEXXD--RKPG--XGIY*Y 533
+L LV G D KPG G+Y Y
Sbjct: 259 PKLLVQLVDAGYLGDPSLKPGSKGGVYEY 287
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 65.3 bits (152), Expect = 8e-10
Identities = 29/83 (34%), Positives = 47/83 (56%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P H ILATNTS+I +N +G +D+ G HFF+P +M LLE+++++ S
Sbjct: 413 VCPPHCILATNTSTIDLNVVGEKTNSQDRIIGAHFFSPAHIMPLLEIVRTEKTSPQAILD 472
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
++ GK + K + + GF V
Sbjct: 473 LITVGKMIKKVPVVVGNCTGFAV 495
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 64.9 bits (151), Expect = 1e-09
Identities = 35/107 (32%), Positives = 59/107 (55%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L PE ILATNTSS+S++ + S +K ++ +HFFNPV + L+EV S S D +
Sbjct: 374 LKPE-AILATNTSSLSLDELSSVLKNPERLVAIHFFNPVAKLPLVEVASSQQTSADIAEK 432
Query: 184 MMEWGKSVGKTCITCKDTPGFVVKGS*LRTVLKR*GCTKEEMRQQKI 324
+ + ++ K + +PGF+V + + +L+ C E ++I
Sbjct: 433 ALAFVGAIDKLPLAVSSSPGFLVNRALMAYLLEANRCLDEGFSMEQI 479
Score = 40.7 bits (91), Expect = 0.021
Identities = 38/93 (40%), Positives = 43/93 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R L Y EA R + G S E ID A G P+GP+ELAD GLD+ S+ A LK
Sbjct: 457 RALMAYLLEANRCLDEG-FSMEQIDKAAT-DFGMPIGPIELADRIGLDICLSV-AQHLKN 513
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
E L LVK G K G G Y Y
Sbjct: 514 FYKHA-EVSERLKTLVKEGH-LGAKTGQGFYHY 544
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 64.9 bits (151), Expect = 1e-09
Identities = 38/88 (43%), Positives = 47/88 (53%)
Frame = +3
Query: 270 YSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPV 449
Y +A MYE+ AS + IDTAMRLG G P GPL D GLD+ + L + + TG+
Sbjct: 183 YLNDAATMYEQRYASRDGIDTAMRLGCGLPRGPLAHLDAIGLDVARDTLDALHERTGDRR 242
Query: 450 FEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
F P VL +V G K G G Y Y
Sbjct: 243 FLPAPVLTHMVAAG-LLGLKAGRGFYDY 269
Score = 62.9 bits (146), Expect = 4e-09
Identities = 30/78 (38%), Positives = 45/78 (57%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+LAT+TSS+ V R + G+HFFNP PVM+L+EV+++ S +T
Sbjct: 399 TVLATSTSSLPVIECAMATGRPEAVVGMHFFNPAPVMKLVEVVRTALTSRETLGVAHATA 458
Query: 199 KSVGKTCITCKDTPGFVV 252
++GK + C D GF+V
Sbjct: 459 TALGKRPVGCLDRSGFIV 476
Score = 60.9 bits (141), Expect = 2e-08
Identities = 35/89 (39%), Positives = 47/89 (52%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L PY A+ + + G +AE IDT M LG G+PMGPL+L D GLD+ +IL +
Sbjct: 479 LLFPYLNRAVALLDEGILTAEGIDTVMALGQGHPMGPLQLLDVIGLDVSVAILRTLHTTF 538
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXGI 524
P L+ LV G RK G G+
Sbjct: 539 REQRLLPSRPLEQLVAAGH-LGRKRGKGL 566
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +1
Query: 16 HTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
HTI A+NTSS+ ++ I + +R ++ GLH+F+PV M L+EVI + SE+T +
Sbjct: 424 HTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVAL 483
Query: 196 GKSVGKTCITCKDTPGFVV 252
+ GKT I D GF V
Sbjct: 484 ARKQGKTAIVVADRAGFYV 502
Score = 55.6 bits (128), Expect = 7e-07
Identities = 34/94 (36%), Positives = 52/94 (55%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILAPY EA R G+ E +D A+ + G+P+GP+ L D G+D+ I+ +++++
Sbjct: 504 RILAPYINEAARCLLDGEP-IESVDNAL-VDFGFPVGPMMLLDEVGIDVATKIMPILVEQ 561
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G P F D ++K G RK G G Y Y+
Sbjct: 562 LG-PRFAAPPSFDVILKDGR-KGRKNGRGFYLYS 593
>UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11;
Burkholderia|Rep: 3-hydroxybutyryl-CoA epimerase -
Burkholderia xenovorans (strain LB400)
Length = 714
Score = 64.5 bits (150), Expect = 1e-09
Identities = 31/79 (39%), Positives = 46/79 (58%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P H I A+NTS++ +N + S R F GLHFF+PV M L+EVI S++T +
Sbjct: 419 PAHAIFASNTSALPINELASASARPQNFIGLHFFSPVSRMALVEVIVGSATSDETLARSL 478
Query: 190 EWGKSVGKTCITCKDTPGF 246
++ + + KT I +D GF
Sbjct: 479 DYIQQIHKTPIVVRDGYGF 497
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 64.5 bits (150), Expect = 1e-09
Identities = 31/79 (39%), Positives = 45/79 (56%)
Frame = +1
Query: 16 HTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
H ILATNTS+I +N +G +D+ G HFF+P VM LLEV++++ S +M
Sbjct: 416 HCILATNTSTIDLNLVGEKTSSQDRIIGAHFFSPAHVMPLLEVVRTEKTSAQVILDLMTV 475
Query: 196 GKSVGKTCITCKDTPGFVV 252
GK++ K + GF V
Sbjct: 476 GKAIKKIPVVVGSCTGFAV 494
>UniRef50_Q12AF3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=40; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 699
Score = 64.1 bits (149), Expect = 2e-09
Identities = 30/76 (39%), Positives = 45/76 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILA+NTS++ +N I S KR G HFF+P VM+LLEV++ + ++D +M GK
Sbjct: 407 ILASNTSTLDMNQIASFTKRPQDVIGTHFFSPANVMKLLEVVRGEKTAKDVLATVMALGK 466
Query: 202 SVGKTCITCKDTPGFV 249
+ KT + GF+
Sbjct: 467 KIKKTAVVSGVCDGFI 482
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 63.7 bits (148), Expect = 3e-09
Identities = 33/80 (41%), Positives = 47/80 (58%), Gaps = 3/80 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
TI+++NTS IS+ A+ G K F G HFFNP ++LLE+I ++H D M
Sbjct: 130 TIVSSNTSGISIAAMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTEHTDPDVVAYMKS 189
Query: 193 WGKSV-GKTCITCKDTPGFV 249
+G+ V GK + KDTP F+
Sbjct: 190 FGEDVLGKGVVMAKDTPNFI 209
>UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 748
Score = 63.7 bits (148), Expect = 3e-09
Identities = 28/77 (36%), Positives = 48/77 (62%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+LA+NTS++ V+ I + + R + F G+HFF+P VM+LLEV+++ S + M G
Sbjct: 453 TVLASNTSALDVDEIAAALDRPEDFVGMHFFSPANVMKLLEVVQAAKSSPEAILTAMAVG 512
Query: 199 KSVGKTCITCKDTPGFV 249
+ +GK + + GF+
Sbjct: 513 RKIGKVPVWSGNCDGFI 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/93 (37%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R++A SA+A R+ +RG A +D A+ G+PMGPL D +GLD+ +I K
Sbjct: 532 RMVAKRSAQAERLLQRG-AFPPQVDAALTK-LGFPMGPLTTNDMSGLDIGYAI----RKR 585
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G P PI D +V+ G+ +K G G Y Y
Sbjct: 586 RGTPF--PIA--DAIVESGQ-LGQKTGSGYYRY 613
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 63.7 bits (148), Expect = 3e-09
Identities = 29/77 (37%), Positives = 48/77 (62%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I+A+NTSS+S+ +I + ++ ++ G+HFFNP P+M+L+EVI + S++ +
Sbjct: 112 IIASNTSSLSIASIAASLQNPERCIGIHFFNPAPLMKLVEVIPAVQTSQNVLDTCVAEIT 171
Query: 202 SVGKTCITCKDTPGFVV 252
K KDTPGF+V
Sbjct: 172 RWKKVVAIAKDTPGFIV 188
Score = 56.8 bits (131), Expect = 3e-07
Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ P+ EALRMYE G A+ ID AM+ G+ MGP EL D+ G D+ ++ +
Sbjct: 190 RVARPFYGEALRMYEEGVANFATIDAAMKSVGGFRMGPFELMDFIGNDVNYTVTETVFNA 249
Query: 435 -TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+P ++P + G RK G G Y Y
Sbjct: 250 FYQDPRYKPSFTQQRYSQAG-YLGRKSGRGYYDY 282
Score = 35.1 bits (77), Expect = 1.0
Identities = 17/29 (58%), Positives = 18/29 (62%)
Frame = +3
Query: 309 ASAEDIDTAMRLGAGYPMGPLELADYTGL 395
ASAEDID AM G YP G L AD G+
Sbjct: 329 ASAEDIDNAMTKGVNYPKGLLAWADEKGI 357
>UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 293
Score = 63.7 bits (148), Expect = 3e-09
Identities = 34/88 (38%), Positives = 48/88 (54%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L PY + + Y+ G A+AEDID A++LG GY GPLEL D GLD++ T
Sbjct: 198 LLLPYLNDVISEYDDGLATAEDIDLALKLGLGYKSGPLELLDMIGLDVQLHATEAAYAAT 257
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXG 521
+P + P +L +V G + K G G
Sbjct: 258 ADPRYAPPPLLRQMVAAGRLGN-KAGNG 284
Score = 59.3 bits (137), Expect = 6e-08
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = +1
Query: 16 HTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
+T + TNTS++SV + + + + GLHFFNP P+ R +EV+++ E+ ++
Sbjct: 116 NTPICTNTSALSVTELAAALPNPSRVAGLHFFNPAPLQRTVEVVRALQTGEELVDRLVAL 175
Query: 196 GKSVG-KTCITCKDTPGFVV 252
++G K I KD PGF++
Sbjct: 176 VDTLGNKDPIVVKDRPGFLL 195
>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
Pseudomonas putida W619
Length = 423
Score = 62.9 bits (146), Expect = 4e-09
Identities = 31/82 (37%), Positives = 50/82 (60%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L PE ILA+NTS++ ++AI + R ++ GLHFF+P VM+LLEV++ + A
Sbjct: 123 LKPE-AILASNTSALDIDAIAAVTGRPEQVLGLHFFSPAHVMKLLEVVRGQLTAPAVLDA 181
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+ G+ +GK + + PGF+
Sbjct: 182 AVALGQRMGKEVVVAGNCPGFI 203
Score = 36.3 bits (80), Expect = 0.45
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L Y AEA ++ G A+ +D A++ G G+ MGP + D G+DL+ + +
Sbjct: 206 RMLRTYVAEARQLLLEG-ATPRQVDGALQ-GFGFAMGPFRMYDVVGIDLEWRARQLAGQG 263
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
P+ + L L + G+ K G G Y Y
Sbjct: 264 MDAPLVQVDNALCALGRFGQ----KVGQGYYLY 292
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 62.5 bits (145), Expect = 6e-09
Identities = 29/81 (35%), Positives = 47/81 (58%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L E+ I +NTS++ + + +G R + F GLHFF+PV M LLE+I + S++T
Sbjct: 421 LLAENGIWGSNTSTLPITRLATGATRPENFVGLHFFSPVDKMPLLEIIAGEKTSDETLAR 480
Query: 184 MMEWGKSVGKTCITCKDTPGF 246
++ + + KT I D+ GF
Sbjct: 481 AFDFARQIRKTPIIVGDSTGF 501
>UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 712
Score = 62.5 bits (145), Expect = 6e-09
Identities = 30/76 (39%), Positives = 42/76 (55%)
Frame = +1
Query: 25 LATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS 204
LA+NTSSI ++ + G+ ++ GLHFFNPV M L+EVIK D S+ T M +
Sbjct: 428 LASNTSSIPIDELARGLAHPERLVGLHFFNPVEKMLLVEVIKGDKTSQQTLDRAMAFAAL 487
Query: 205 VGKTCITCKDTPGFVV 252
+ + PGF V
Sbjct: 488 IKRVPTPVNSAPGFFV 503
Score = 39.1 bits (87), Expect = 0.063
Identities = 21/49 (42%), Positives = 27/49 (55%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL 401
R+L PY EA+ M++ G AE +D A G MGP E D GLD+
Sbjct: 505 RVLTPYLLEAMIMFDEG-VPAETLDAAAE-EFGMAMGPAETVDLVGLDI 551
>UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Plesiocystis pacifica SIR-1
Length = 789
Score = 62.5 bits (145), Expect = 6e-09
Identities = 34/84 (40%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
A E TILA+NTS I + I + +++F GLHFFNP M LLEVI S + ++
Sbjct: 104 AKETTILASNTSGIPIADIAEALDEGARERFLGLHFFNPPRWMHLLEVIPSKYTAKKYVD 163
Query: 181 AMMEWGKSV-GKTCITCKDTPGFV 249
+ ++ V GK + C+DTP F+
Sbjct: 164 EVAKFSDEVLGKGVVLCRDTPNFI 187
Score = 31.9 bits (69), Expect = 9.6
Identities = 13/26 (50%), Positives = 18/26 (69%)
Frame = +3
Query: 318 EDIDTAMRLGAGYPMGPLELADYTGL 395
++ID AMR G G+ +GP EL D G+
Sbjct: 371 KEIDDAMRWGYGWQLGPFELMDAAGV 396
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 62.5 bits (145), Expect = 6e-09
Identities = 31/83 (37%), Positives = 49/83 (59%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P+ ++ATNTSS+SV + S ++ + G HFFNPV V+ L+EVI++ S +
Sbjct: 422 LRPD-AVIATNTSSLSVTEMASVLRVPGRMLGFHFFNPVAVLPLVEVIRTAQTSGEALAT 480
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ + + KT + KD P F+V
Sbjct: 481 AFDLARKLRKTGVLVKDAPAFLV 503
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 62.5 bits (145), Expect = 6e-09
Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I ATNTS+I ++ + R++KF GLHF NP +M L+E+I + +E+T + ++ K
Sbjct: 113 IFATNTSTIPISYLAEVTGRQEKFIGLHFMNPPVLMPLVEIIMGNKTAEETLKTTIDLAK 172
Query: 202 SVGKTCITC-KDTPGFVV 252
+ K + KD PGF++
Sbjct: 173 KINKDYVVVKKDVPGFLI 190
Score = 51.2 bits (117), Expect = 1e-05
Identities = 31/94 (32%), Positives = 47/94 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI+AP EA + +SA+DI+ M G +P GPL AD G+D L +
Sbjct: 304 RIIAPAVNEAAWILRNDVSSAQDIEKGMVKGMNWPQGPLTFADKYGIDNVLKFLEERYEV 363
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
T N ++P +L +V +G+ K G G + +N
Sbjct: 364 TKNEYYKPDPLLTEMVSKGK-LGVKSGEGFFKWN 396
Score = 47.6 bits (108), Expect = 2e-04
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSI-LAVMLKETGNPVFE 455
EA+ +Y+ G S EDID R G PMG LEL D+TG+D+ + L + + G P
Sbjct: 200 EAVLLYDEG-YSKEDIDAMSRFRLGMPMGFLELMDFTGIDVAYNAGLEAIKRGEGEP--P 256
Query: 456 PIGVLDXLVKRGEXXDRKPGXGIY*Y 533
VL LV+ G K G G Y Y
Sbjct: 257 HFKVLKKLVEEGR-LGIKSGKGFYTY 281
>UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 953
Score = 62.1 bits (144), Expect = 8e-09
Identities = 28/76 (36%), Positives = 45/76 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILA+NTS++ ++ + S R DK G+HFF+P +M+LLE ++ S +T M+ GK
Sbjct: 436 ILASNTSTLDIDEMASATTRPDKVMGMHFFSPAHIMKLLENVRGKDTSPETMATAMDLGK 495
Query: 202 SVGKTCITCKDTPGFV 249
+ K + + P FV
Sbjct: 496 RMKKISVLVGNCPAFV 511
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 62.1 bits (144), Expect = 8e-09
Identities = 30/86 (34%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGI--KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDT 174
+ PE ++A+NTS++ ++ +G+ + +R+ +F G H+F+PV M L+EV+ + S +T
Sbjct: 118 EACPEACVIASNTSTLPISTLGAALSPERRPRFLGAHYFSPVSRMLLVEVVPAFETSPET 177
Query: 175 YQAMMEWGKSVGKTCITCKDTPGFVV 252
K +GK I KD PGF V
Sbjct: 178 VAWTTSLLKRIGKQPIAVKDVPGFAV 203
Score = 54.0 bits (124), Expect = 2e-06
Identities = 34/88 (38%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L EA+R+ E G A+ ED+DTA RLG G+P+GP L D L + + L+E
Sbjct: 205 RMLHAMLIEAVRLVEEGVATPEDLDTACRLGLGHPIGPFALMDNVTSSLCLQVQEI-LQE 263
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDR-KPG 515
+ F P +L V G R KPG
Sbjct: 264 SYGERFRPPALLKQRVAAGYSGGRGKPG 291
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 61.7 bits (143), Expect = 1e-08
Identities = 39/93 (41%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R++ Y EA ++ E G A ED+D AM G PMGP +++D GLD+ SI K
Sbjct: 495 RMVHRYGDEARKIVEEG-ARPEDVDAAMN-ALGLPMGPFQMSDMAGLDIGYSIRQHQAKV 552
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G P EP G LD +VK G + G GIY Y
Sbjct: 553 RGEP--EPDGWLDRIVKTGRKGQKTQG-GIYDY 582
Score = 60.1 bits (139), Expect = 3e-08
Identities = 30/82 (36%), Positives = 46/82 (56%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A ILA+NTS++ VN I S R ++ GLHFF+P VM+LLE++++D S+
Sbjct: 411 IAKPGAILASNTSTLDVNEIASVTGRPEQVIGLHFFSPANVMKLLEIVRADKTSDSVLAT 470
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+ K + K + GFV
Sbjct: 471 SLALAKRIKKVGVVVGVCDGFV 492
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 61.7 bits (143), Expect = 1e-08
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P ILATNTS + + AI S R ++ G HF+ P ++ L+EV+ SD+ S D
Sbjct: 110 LCPPSVILATNTSGLPITAIASAAARPERVLGTHFYMPAYLIPLVEVVCSDYTSPDVAGD 169
Query: 184 MMEWGKSVG-KTCITCKDTPGFV 249
+ + +S+G K + KD PGF+
Sbjct: 170 TVAFLQSIGRKPVLVKKDIPGFI 192
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMR--LGAGYP-MGPLELADYTGLDLKKSILAVM 425
R+ + EA+ + ++G ASA+DIDT R LG + GPLE D GLD+ + +
Sbjct: 195 RLQHAIAREAISLLQKGIASAQDIDTVARYTLGLRFAHTGPLEQRDLNGLDVHLDVAEYL 254
Query: 426 LKETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
+ N +P+ +L V+ G K G G Y
Sbjct: 255 YQSLEN-CTQPLAILREKVESG-CLGLKTGRGFY 286
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 61.3 bits (142), Expect = 1e-08
Identities = 30/82 (36%), Positives = 47/82 (57%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P TILATNTS ++ + + + R D+ GLHFF+P +MRLLEV++ S++T
Sbjct: 398 LLPPATILATNTSYLNPDELAAVTNRTDRVLGLHFFSPANIMRLLEVVRCAETSDETLAT 457
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+ + + + K I GF+
Sbjct: 458 GIAFARKIKKLSIVTGVCEGFI 479
Score = 39.9 bits (89), Expect = 0.036
Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL--KKSILAVML 428
R+ + Y EA +M G A EDID AM G+PMG + D GL++ + A
Sbjct: 482 RMFSAYRTEAEKMLAEG-AYPEDIDRAME-AYGFPMGLFAVYDMAGLEIAWARRKRAAAS 539
Query: 429 KETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
++ P F+ V D L + G RK G G Y Y
Sbjct: 540 RDPNLPYFD---VADKLCEAGR-FGRKAGLGWYRY 570
>UniRef50_A1VP66 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Polaromonas naphthalenivorans CJ2|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Polaromonas naphthalenivorans (strain CJ2)
Length = 686
Score = 60.9 bits (141), Expect = 2e-08
Identities = 30/76 (39%), Positives = 43/76 (56%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTS + V+AI R GLHFF+P VM+LLEV++ + + D M GK
Sbjct: 402 VLATNTSYLDVDAIAQLTARPQDVLGLHFFSPANVMKLLEVVRGERTAADVVATGMALGK 461
Query: 202 SVGKTCITCKDTPGFV 249
+ K + C + GF+
Sbjct: 462 KLKKLPVLCGNAFGFI 477
Score = 38.7 bits (86), Expect = 0.084
Identities = 29/88 (32%), Positives = 43/88 (48%)
Frame = +3
Query: 270 YSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPV 449
Y + M E G A E +D A+ G+ MGP +AD +GLD+ + + +P
Sbjct: 485 YRKQCEFMLEDG-AWPEAVDQALT-DLGFAMGPFAVADLSGLDIAWRMRKAQ-AASRDPR 541
Query: 450 FEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+G+LD L ++G RK G G Y Y
Sbjct: 542 ERYVGILDQLCEQGR-LGRKTGAGYYRY 568
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 60.9 bits (141), Expect = 2e-08
Identities = 29/77 (37%), Positives = 46/77 (59%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
TILATNTS +++N I + +R + GLHFF+P VM+LLEV++ + + + M+
Sbjct: 414 TILATNTSRLNINEIAAVTQRPEDVIGLHFFSPANVMKLLEVVRGERTCDAVIASCMQMA 473
Query: 199 KSVGKTCITCKDTPGFV 249
++GK + GFV
Sbjct: 474 VAIGKIPVLVGVCEGFV 490
Score = 40.3 bits (90), Expect = 0.027
Identities = 32/93 (34%), Positives = 45/93 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L Y EA + E G A+ + ID AM+ G+ MGPL +AD GLD+ + L
Sbjct: 493 RMLTGYWREAGFLLEEG-ATVQQIDAAMQ-AFGFAMGPLAMADLAGLDINWA-TRKRLAS 549
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T V D + ++G +K G G Y Y
Sbjct: 550 TRASHLRYSRVADSICEQGR-FGQKTGAGYYRY 581
>UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Xanthomonadaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 693
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/83 (36%), Positives = 49/83 (59%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P+ +L TNTSSI + + I+R +F GLH+FNPV +M L+E+++ D +
Sbjct: 418 LKPD-ALLTTNTSSIPLTDLRGHIQRPAQFAGLHYFNPVAMMPLVEIVQHDGLDPANVAR 476
Query: 184 MMEWGKSVGKTCITCKDTPGFVV 252
+ + K++ K + TPGF+V
Sbjct: 477 LAAFCKTLDKFPVPVAGTPGFLV 499
Score = 41.5 bits (93), Expect = 0.012
Identities = 30/91 (32%), Positives = 43/91 (47%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L PY EA Y G TA++ G PMGP+EL D GLD+ + A +
Sbjct: 501 RVLFPYLLEAATAYAEGIPGPVLDKTAVKFGM--PMGPIELIDTVGLDVAAGVGAELAPF 558
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
P+ + ++ KRG +K G G+Y
Sbjct: 559 LRLPIPAALATVE-AGKRG----KKDGQGLY 584
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 60.5 bits (140), Expect = 2e-08
Identities = 26/76 (34%), Positives = 45/76 (59%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+LA+NTS++ ++ I G+ + G+H+F+PVP + LLE++ ++ S++ G
Sbjct: 427 TVLASNTSALPISTIAEGVDDPSRVLGMHYFSPVPDIPLLEIVVTEETSDEALATAYAAG 486
Query: 199 KSVGKTCITCKDTPGF 246
+ KT I D PGF
Sbjct: 487 LAQDKTVIVVNDGPGF 502
Score = 53.6 bits (123), Expect = 3e-06
Identities = 37/94 (39%), Positives = 48/94 (51%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILA Y EAL ++E G A E +D AM + AG+PMGP EL D GLD+ I VM E
Sbjct: 506 RILALYMNEALLLFEAG-AEIEAVDEAM-MDAGFPMGPFELFDLVGLDVAAKITDVM-GE 562
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+P I + + +K G Y Y+
Sbjct: 563 ALSPERVDISDRAGRLAEADLLGQKTNRGFYEYD 596
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/78 (38%), Positives = 44/78 (56%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ TI A+NTSSI + + G +R + G+H+F+PV M LLE+I ++ +E
Sbjct: 457 DQTIFASNTSSIPITELAKGSRRPAQVIGMHYFSPVHKMPLLEIITHAGTADWVTATCVE 516
Query: 193 WGKSVGKTCITCKDTPGF 246
G+ GKT I D PGF
Sbjct: 517 VGRKQGKTVIVVNDGPGF 534
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/93 (33%), Positives = 47/93 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILAPY EA + G A ++D A+ + G+P+GP+ L D G+D+ + + +M
Sbjct: 538 RILAPYMNEAAYLLAEG-ADIAELDRAL-VEFGFPVGPITLLDEVGIDVAQKVGPIMEAA 595
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G + P L+ +V G RK G Y Y
Sbjct: 596 FGKRMAAP-KALEKVVADGR-LGRKTQKGFYLY 626
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 60.5 bits (140), Expect = 2e-08
Identities = 25/67 (37%), Positives = 44/67 (65%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ ILATNTS + +N+I R D+ GLHFF+P VM+L+E++++++ ++D + M+
Sbjct: 412 DSAILATNTSYLDINSIAKVTSRPDQVVGLHFFSPAHVMKLIEIVRAENTADDVIKTMLA 471
Query: 193 WGKSVGK 213
G + K
Sbjct: 472 LGVKLRK 478
>UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=36; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 740
Score = 60.1 bits (139), Expect = 3e-08
Identities = 31/83 (37%), Positives = 45/83 (54%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I A+NTS+I + ++ KR F GLHFF+PV M L+E+I + M++ +
Sbjct: 437 IFASNTSTIPITSLAKNSKRPKNFIGLHFFSPVDRMMLVEIILGKKTGDKALALAMDYVR 496
Query: 202 SVGKTCITCKDTPGFVVKGS*LR 270
++ KT I DT GF V LR
Sbjct: 497 AIRKTPIVVNDTRGFYVNRCVLR 519
Score = 49.2 bits (112), Expect = 6e-05
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R + Y EA M G A I+ A ++ AG P+GPL L D T +DL + I+ +++
Sbjct: 515 RCVLRYMQEAYSMLIEG-VPAPMIENAAKM-AGMPVGPLALTDETAIDLAQKIMKQTIRD 572
Query: 435 TGNPVFEP--IGVLDXLVKRGEXXDRKPGXGIY*Y 533
G +P + ++D +V + RK G G Y Y
Sbjct: 573 LGEKAVDPRHMELIDMMVDKHGRHGRKNGKGFYEY 607
>UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=1; Moritella sp. PE36|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Moritella sp. PE36
Length = 698
Score = 60.1 bits (139), Expect = 3e-08
Identities = 28/78 (35%), Positives = 46/78 (58%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ I+A+NTS++ ++++ + + + F GLHFF+PV M L+E+IK D S T A +
Sbjct: 416 DELIMASNTSTLPISSLATASTKPENFIGLHFFSPVDKMPLVEIIKGDKTSSATLAAAYD 475
Query: 193 WGKSVGKTCITCKDTPGF 246
+GK I D+ GF
Sbjct: 476 LVIQIGKVPIVVNDSRGF 493
Score = 39.5 bits (88), Expect = 0.048
Identities = 29/76 (38%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Frame = +3
Query: 255 RILAPYSAEALRMYERG-DASAEDIDTAMRLGAGYPM---GPLELADYTGLDLKKSILAV 422
R+L S EALR YE G S D + LG G+P G L+ D+ G+D K A
Sbjct: 621 RLLFVQSLEALRAYEEGVVTSTRDANIGSILGLGFPAWTGGVLQFIDHHGVDDFKQ-RAE 679
Query: 423 MLKETGNPVFEPIGVL 470
L E P F P+ +L
Sbjct: 680 QLCEQFGPQFTPVAIL 695
Score = 33.5 bits (73), Expect = 3.1
Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL---KKSILAVM 425
R+ Y +E +RM G AE I+ A + AG P+GPL + D L L ++ +
Sbjct: 497 RVFFTYVSEGMRMLSEG-IPAEVIENAA-IQAGLPVGPLAITDEVSLSLIDHVRNQARLD 554
Query: 426 LKETGNPVFE-PI-GVLDXLVKRGEXXDRKPGXGIY*YN 536
K G + + P VLD L+ + + G G Y YN
Sbjct: 555 FKAEGKELLDNPADAVLDKLLAL-KRRGKLAGAGFYDYN 592
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 59.7 bits (138), Expect = 4e-08
Identities = 29/84 (34%), Positives = 53/84 (63%), Gaps = 3/84 (3%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGS--GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
AP HT+LA+NTS I + IG G + + + G H++NP ++ L+EV++++H S ++
Sbjct: 103 APPHTVLASNTSVIPITEIGEMLGSEARARLVGTHWWNPPHLVPLVEVVRTEHTSLSVFE 162
Query: 181 AMMEWGKSVGKTCITC-KDTPGFV 249
+ E +S+GK+ + +D GF+
Sbjct: 163 STFELLQSLGKSPVKVNRDVAGFI 186
>UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=3; Rhodobacterales|Rep: Putative fatty
acid oxidation complex alpha subunit - Oceanicola
batsensis HTCC2597
Length = 686
Score = 59.3 bits (137), Expect = 6e-08
Identities = 39/94 (41%), Positives = 51/94 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILAPY EA+ M + G AE ID A L G PMGP+ LAD GLD+ + + +
Sbjct: 501 RILAPYMMEAMLMLDDGHDKAE-IDRAA-LAFGMPMGPVTLADQVGLDICLEVGKSLQQG 558
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
PV P L V++GE +K G G+Y Y+
Sbjct: 559 LDTPVAAPPDWLRDKVEKGE-TGKKAGKGLYDYD 591
Score = 56.8 bits (131), Expect = 3e-07
Identities = 28/77 (36%), Positives = 42/77 (54%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTSS+ + ++ +F GLHFFNPV M L+E++ D S +T + +
Sbjct: 423 ILATNTSSLPLASLVDAAPDPARFAGLHFFNPVSKMPLVEIVSHDMASTETLDRLAAFTV 482
Query: 202 SVGKTCITCKDTPGFVV 252
+ + D PGF+V
Sbjct: 483 GIDRLPARVTDYPGFLV 499
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 58.8 bits (136), Expect = 7e-08
Identities = 28/77 (36%), Positives = 46/77 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTSSI + + + + R D+ GLHFFNPV ++L+EV+ D + + +
Sbjct: 446 ILATNTSSIPLQDLRTTLARPDRLVGLHFFNPVSRLQLVEVVSHDGNDAQVLREALAFVG 505
Query: 202 SVGKTCITCKDTPGFVV 252
++ + + K +PGF+V
Sbjct: 506 AIDRLPLAVKSSPGFLV 522
Score = 38.3 bits (85), Expect = 0.11
Identities = 31/91 (34%), Positives = 42/91 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R L Y EA+ M + ID A G PMGP+ELAD GLD+ + ++ +
Sbjct: 524 RALTLYMLEAMVMLDE-KIDQRLIDAAAEQ-FGMPMGPIELADQVGLDICLDVGDMLRTK 581
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
G+ + L V +GE RK G G Y
Sbjct: 582 FGDLLPPTPAWLREKVAKGE-LGRKTGRGFY 611
>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 714
Score = 58.8 bits (136), Expect = 7e-08
Identities = 28/78 (35%), Positives = 44/78 (56%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E+ + A+NTS++ + + + F GLHFF+PV M L+E+IK S T ++
Sbjct: 422 ENGLFASNTSTLPITGLAEASASPENFIGLHFFSPVDRMPLVEIIKGKKTSSRTLAHAID 481
Query: 193 WGKSVGKTCITCKDTPGF 246
+ K +GKT I D+ GF
Sbjct: 482 FVKQIGKTPIVVNDSRGF 499
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 58.8 bits (136), Expect = 7e-08
Identities = 31/76 (40%), Positives = 41/76 (53%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
IL NTSSI + I S + + G+HF NP P+M ++EVIK H E T + +
Sbjct: 114 ILGVNTSSIPITKIASLVDHPQRVIGVHFMNPAPMMPMVEVIKGYHTDELTIEKTRTLLE 173
Query: 202 SVGKTCITCKDTPGFV 249
V K I KD+ GFV
Sbjct: 174 QVHKKMIVVKDSVGFV 189
Score = 49.6 bits (113), Expect = 4e-05
Identities = 31/93 (33%), Positives = 43/93 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R + + EA+ M + AS EDID + G+ MGPL AD GLD L + E
Sbjct: 192 RAMMIFINEAIFMVQENIASIEDIDVLFKQCFGHKMGPLHTADLIGLDTVLYSLETIYSE 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+P + P +L +V G +K G Y Y
Sbjct: 252 LNDPKYRPCWLLRNMVDAG-LLGQKTKKGFYQY 283
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 58.8 bits (136), Expect = 7e-08
Identities = 29/76 (38%), Positives = 43/76 (56%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LA+NTS S++AI + R + G+HFF+P VM+LLEV+K S+ M GK
Sbjct: 403 VLASNTSYQSIDAIAAATSRPESVLGMHFFSPANVMKLLEVVKGASSSDIVIATAMAVGK 462
Query: 202 SVGKTCITCKDTPGFV 249
+GK + GF+
Sbjct: 463 KIGKVSVLSGMCYGFI 478
Score = 39.1 bits (87), Expect = 0.063
Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL-KKSILAVMLK 431
R+L Y EA G A+ ID+AM G MGPL ++D GLD+ K+ + +
Sbjct: 481 RMLRHYGREAALCLIEGGTPAQ-IDSAME-SWGMAMGPLAVSDLAGLDIGYKAREQLTAE 538
Query: 432 ETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
+ G+P V D LV+ G +K G G Y Y+
Sbjct: 539 QKGDPA--SYMVADRLVEAGR-LGQKSGAGYYQYD 570
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 58.4 bits (135), Expect = 1e-07
Identities = 26/76 (34%), Positives = 42/76 (55%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTS + ++ I +R G HFF+P V +LLEV++ + + +M G+
Sbjct: 151 ILATNTSGLDIDEIAVVTRRPQDVVGAHFFSPAHVQKLLEVVRGARTAPEVIATLMSLGR 210
Query: 202 SVGKTCITCKDTPGFV 249
+GK + + PGF+
Sbjct: 211 RMGKVSVLSRIYPGFI 226
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 58.4 bits (135), Expect = 1e-07
Identities = 26/76 (34%), Positives = 45/76 (59%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTSS+ ++A+ + R G+HFF+P VMRL+E++ + D A+M+ +
Sbjct: 408 ILATNTSSLDIDALAKMVSRPQDVIGMHFFSPANVMRLVEIVLCQTTAPDVVTAVMDIAR 467
Query: 202 SVGKTCITCKDTPGFV 249
+GK + ++ G +
Sbjct: 468 RIGKLPVISGNSAGSI 483
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 58.4 bits (135), Expect = 1e-07
Identities = 31/78 (39%), Positives = 42/78 (53%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
++ ATNTSS+S+ + + K G+HFFNPV M L+EVIK S + A+
Sbjct: 418 SLFATNTSSLSLTEMQTVAKCPHNIVGMHFFNPVSKMPLVEVIKGKSTSTEAAAAIFNLA 477
Query: 199 KSVGKTCITCKDTPGFVV 252
GK I D PGF+V
Sbjct: 478 LKTGKIPIIVNDGPGFLV 495
Score = 37.9 bits (84), Expect = 0.15
Identities = 30/93 (32%), Positives = 39/93 (41%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL Y AEA R+ +D A+ L G PMGP L D GLD+ + V+
Sbjct: 497 RILGVYMAEAGRLAVDERCHPACVDEAI-LAFGMPMGPFRLLDEVGLDVACHVGPVLANG 555
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ F + +V G RK G Y Y
Sbjct: 556 LKSDRFSVSATISQMVADG-YLGRKNRKGFYTY 587
Score = 37.9 bits (84), Expect = 0.15
Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Frame = +3
Query: 279 EALRMYERGDA-SAEDIDTAMRLGAGYPM---GPLELADYTGLDLKKSILAVMLKETGNP 446
EA R+ + G A S ED+DT M G G+P G L+ AD+ G+ + L + ++T
Sbjct: 629 EATRILDEGIAMSPEDVDTGMVWGTGFPPFRGGLLQYADHRGIANVVAALEQLQRKTKRD 688
Query: 447 VFEPIGVLDXLVKRGE 494
F P L + G+
Sbjct: 689 YFAPTETLKKMAIEGK 704
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 58.0 bits (134), Expect = 1e-07
Identities = 32/85 (37%), Positives = 48/85 (56%), Gaps = 3/85 (3%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGI--KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY 177
+AP + I ATNTS +S+ + G + K +F G+HFFNP M L+E+I + H +
Sbjct: 150 IAP-NAIFATNTSGLSITKLSEGFSDELKSRFCGVHFFNPPRYMHLVELIPTAHTRPEIL 208
Query: 178 QAMMEWGKS-VGKTCITCKDTPGFV 249
+ + S VGK + KDTP F+
Sbjct: 209 DQLETFLTSIVGKGVVRAKDTPNFI 233
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 58.0 bits (134), Expect = 1e-07
Identities = 32/82 (39%), Positives = 45/82 (54%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP + +LA NTS I + +GS K + G+HF NPV + +EVI + SE T
Sbjct: 109 IAP-NAVLAANTSCIPITKLGSFHKTSAQVIGVHFMNPVYLKHTVEVILGLNTSEQTKDR 167
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+E +GK + KD PGFV
Sbjct: 168 CLEMLAMLGKKAVVVKDGPGFV 189
Score = 41.1 bits (92), Expect = 0.016
Identities = 28/93 (30%), Positives = 42/93 (45%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI + EA + G A D+D + G+ MGPLE AD G+D + L V+ +
Sbjct: 192 RISHLFMNEAAFAIQDGIAQPADVDAIFKECFGHKMGPLETADLIGVDTVVNSLDVLYQT 251
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ + ++ +V G RK G G Y Y
Sbjct: 252 FQDSKYRVCPLMRSMVDAGH-LGRKTGKGFYSY 283
>UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 723
Score = 58.0 bits (134), Expect = 1e-07
Identities = 29/75 (38%), Positives = 41/75 (54%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I A+NTSSI + I + G+H+F+PV M LLE+I ++ S++ + GK
Sbjct: 437 IFASNTSSIPITKIAEASAHPETVLGMHYFSPVQKMPLLEIIVTEKTSKEATATAVALGK 496
Query: 202 SVGKTCITCKDTPGF 246
GKT I D PGF
Sbjct: 497 KQGKTVIVVGDGPGF 511
Score = 50.8 bits (116), Expect = 2e-05
Identities = 33/93 (35%), Positives = 50/93 (53%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILAPY EA + G A+ ED+D A+ + G+P+GP+ L D G+D+ + + ++
Sbjct: 515 RILAPYMNEAAELLVEG-AAVEDLDRAL-VEFGFPVGPITLLDEVGIDVGEKVGKILHDA 572
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G + P + D +VK G RK G Y Y
Sbjct: 573 FGARMASPAALHD-VVKAGR-LGRKNRKGFYTY 603
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 58.0 bits (134), Expect = 1e-07
Identities = 30/77 (38%), Positives = 43/77 (55%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I A+NTSS+ + I +R GLH+F+PV M LLEVI + + + M +G+
Sbjct: 440 IFASNTSSLPLARIAQAAERPQNVIGLHYFSPVDRMPLLEVIAHERTAPEVIATAMAFGR 499
Query: 202 SVGKTCITCKDTPGFVV 252
+ GKT I +D GF V
Sbjct: 500 AQGKTPIVVRDGVGFYV 516
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/93 (33%), Positives = 51/93 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILAPY EA+ + E G A + ID A+ + G+P+GP +L D G+D+ + A +L E
Sbjct: 518 RILAPYLNEAVHLLEEGVA-IDRIDQAL-VRFGFPVGPFKLLDEVGIDIIAKV-APVLHE 574
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
P+ ++ +++ + +K G G Y Y
Sbjct: 575 AFGERMRPVSAVERMLE-ADRLGKKNGRGFYRY 606
>UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=6; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 719
Score = 57.6 bits (133), Expect = 2e-07
Identities = 24/73 (32%), Positives = 45/73 (61%)
Frame = +1
Query: 28 ATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV 207
A+NTS++ ++ + R +KF G+HFF+PV M+L+E+I+ ++T ++ +++
Sbjct: 430 ASNTSTLPISGLAVASSRPEKFIGIHFFSPVDKMKLVEIIRGRQTDDETVARAFDYVQAL 489
Query: 208 GKTCITCKDTPGF 246
GK I D+ GF
Sbjct: 490 GKIPIVVNDSRGF 502
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/76 (36%), Positives = 41/76 (53%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LA+NTS + +N I + R GLHFF+P VM+LLEV+ +D + D GK
Sbjct: 400 VLASNTSYLDINQIAAVTSRPQDVLGLHFFSPAHVMKLLEVVIADQTAPDVAATGFALGK 459
Query: 202 SVGKTCITCKDTPGFV 249
+GK + GF+
Sbjct: 460 RLGKVSVRAGVCDGFI 475
Score = 35.5 bits (78), Expect = 0.78
Identities = 31/93 (33%), Positives = 41/93 (44%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL+ Y A M G AS ID A+ G+ MGP +AD GLD+ ++ E
Sbjct: 478 RILSVYRTCADHMILDG-ASPYQIDEALE-EFGFAMGPFAVADLAGLDIGWAVRKRKRAE 535
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+P D L + G +K G G Y Y
Sbjct: 536 GLDPRARDSAYADKLCEAGH-FGQKTGKGYYDY 567
>UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Pelagibacter ubique
Length = 740
Score = 57.2 bits (132), Expect = 2e-07
Identities = 29/79 (36%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDK--FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
I+++NTSSI + + + ++K F HFFNPV M LLE++K+++ D ++ +
Sbjct: 108 IVSSNTSSIPIKILSQHLSEEEKKDFCITHFFNPVRYMGLLEIVKNENNDLDKINSLKAF 167
Query: 196 GKS-VGKTCITCKDTPGFV 249
++ +GK I C DTPGF+
Sbjct: 168 CETELGKGAIICNDTPGFL 186
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/80 (35%), Positives = 43/80 (53%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P IL TNTS++ ++ I + KR GLHFF+P VM LLE+++ + D +
Sbjct: 400 PAGAILGTNTSTLDIDEIANTTKRPADVIGLHFFSPANVMPLLEIVQGKQTAMDVLLTAL 459
Query: 190 EWGKSVGKTCITCKDTPGFV 249
+ K + KT + K GF+
Sbjct: 460 DMAKLIKKTGVVSKVCYGFI 479
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P I A+NTS++ ++ + + D+F GLHFF+PV M L+EVI S++T +
Sbjct: 419 PAQAIFASNTSTLPISQLAQASRSPDQFIGLHFFSPVDRMGLVEVIMGKQTSKETLAKGL 478
Query: 190 EWGKSVGKTCITCKDTPGF 246
++ + KT I D+ GF
Sbjct: 479 DFIAQLRKTPIVVNDSRGF 497
>UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Mariprofundus ferrooxydans PV-1|Rep: Fatty
oxidation complex, alpha subunit - Mariprofundus
ferrooxydans PV-1
Length = 701
Score = 57.2 bits (132), Expect = 2e-07
Identities = 28/78 (35%), Positives = 44/78 (56%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+L +NTSS+S++ + + GLHFFNP P M L+EV+ + + +T +
Sbjct: 411 TLLLSNTSSLSISDMQHRRANAGRIAGLHFFNPAPKMPLVEVVAGEKTTPETVDKVCALA 470
Query: 199 KSVGKTCITCKDTPGFVV 252
S GK I ++PGF+V
Sbjct: 471 VSWGKYPIIVAESPGFLV 488
Score = 37.9 bits (84), Expect = 0.15
Identities = 21/49 (42%), Positives = 28/49 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL 401
R L PY AL++ G+ +D A++ G PMG LELAD GLD+
Sbjct: 490 RCLMPYMVAALKLVASGEKIGH-VDGALKC-FGMPMGALELADRVGLDI 536
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 4/79 (5%)
Frame = +1
Query: 25 LATNTSSISVNAIGSGIK---RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
+++NTS+I + + +G+ R+D F HFFNP MRLLE++ + T A+ +
Sbjct: 131 VSSNTSTIPLGDLTAGLPESFRRD-FLITHFFNPPRYMRLLEIVAGPETNPATVAAVARF 189
Query: 196 GK-SVGKTCITCKDTPGFV 249
+GKT +TCKDTPGF+
Sbjct: 190 ADVKLGKTVVTCKDTPGFI 208
Score = 31.9 bits (69), Expect = 9.6
Identities = 19/54 (35%), Positives = 24/54 (44%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILA 419
++A A A R+ ID AMRLG + GP EL D G +LA
Sbjct: 363 VMAKTLAYAARLVPEAADDIVAIDDAMRLGYNWKFGPFELIDKIGAARLAGLLA 416
>UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA
dehydrogenase/ 3-hydroxybutyryl-CoA epimerase; n=1;
Rhodococcus sp. RHA1|Rep: Bifunctional 3-hydroxyacyl-CoA
dehydrogenase/ 3-hydroxybutyryl-CoA epimerase -
Rhodococcus sp. (strain RHA1)
Length = 428
Score = 56.8 bits (131), Expect = 3e-07
Identities = 26/76 (34%), Positives = 44/76 (57%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+LA+ TS++ + + S ++R F G+HFF+PV M L+E + S+ T A + +
Sbjct: 137 TVLASTTSTLPIATLSSKLQRPQYFIGMHFFSPVDRMSLVETVVGSRTSQATVAASLTYA 196
Query: 199 KSVGKTCITCKDTPGF 246
+ +GK I D+ GF
Sbjct: 197 RRLGKVPIVVGDSRGF 212
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 56.8 bits (131), Expect = 3e-07
Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
E T++ +NTS I +N + G + F G HFFNP + L E+I S + +
Sbjct: 129 EGTLITSNTSGIPINLMSEGRSEDFQKHFCGTHFFNPPRYLELFEIIPGPKTSPEVLDFL 188
Query: 187 MEWG-KSVGKTCITCKDTPGFV 249
+G K +GKT I KDTP F+
Sbjct: 189 NGYGEKFLGKTSIVAKDTPAFI 210
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 56.8 bits (131), Expect = 3e-07
Identities = 30/82 (36%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
E TI+A+NTS++ + + + K +F HFFNP M L+E+I + I ++ + +
Sbjct: 114 EDTIIASNTSTLPLKKLKENLPNNIKSRFIITHFFNPPRYMELVELIIDNTIKDEVIEKI 173
Query: 187 MEW-GKSVGKTCITCKDTPGFV 249
+ K +GKT I C DTPGF+
Sbjct: 174 SVFLTKILGKTIIKCNDTPGFI 195
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 56.0 bits (129), Expect = 5e-07
Identities = 27/78 (34%), Positives = 43/78 (55%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E I A+NTS++ + + KR ++F GLHFF+PV M L+E+I + + T +
Sbjct: 429 ETAIYASNTSTLPITELAKASKRPNQFIGLHFFSPVDKMPLVEIIVGEETDDATLAKGFD 488
Query: 193 WGKSVGKTCITCKDTPGF 246
+ + KT I D+ GF
Sbjct: 489 YVGQIAKTPIVVNDSRGF 506
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 55.6 bits (128), Expect = 7e-07
Identities = 27/76 (35%), Positives = 39/76 (51%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
IL TNTS++ V+ I +R GLHFF+P PVM LLE+++ D A +
Sbjct: 397 ILGTNTSTLDVDRIAHSTRRPQDVVGLHFFSPAPVMPLLEIVRGAATHADVVAAAQGLAR 456
Query: 202 SVGKTCITCKDTPGFV 249
+ KT + GF+
Sbjct: 457 RLRKTAVVAGVCDGFI 472
Score = 34.3 bits (75), Expect = 1.8
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
Frame = +3
Query: 255 RILAPYSAEALRMYERG-DASAEDIDTAMRLGAGYPM---GPLELADYTGLDLKKSILAV 422
R L EA R+ E G ASA D+D G G+P GP AD GL +++A
Sbjct: 601 RCLHALVVEAARLLEEGIAASATDVDAVFLAGYGFPRWRGGPCHSADAMGL---PAVVAG 657
Query: 423 MLKE--TGNPVF-EPIGVLDXLVKRG 491
+ + T P F +P G+L L +G
Sbjct: 658 LRRRAATAEPEFWQPPGLLVRLAAQG 683
Score = 33.9 bits (74), Expect = 2.4
Identities = 20/53 (37%), Positives = 29/53 (54%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSI 413
R+ Y +A M G A ++D A+R G+ MGP ++AD GLD+ SI
Sbjct: 475 RMWHQYLRQAALMVHEG-AMPMEVDAALR-DWGFAMGPFQVADLAGLDVGDSI 525
>UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation
complex; n=5; Betaproteobacteria|Rep: Alpha-subunit of
fatty acid oxidation complex - Azoarcus sp. (strain
EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 678
Score = 55.6 bits (128), Expect = 7e-07
Identities = 29/101 (28%), Positives = 51/101 (50%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTSS+ + IG+ + + G+HFFNPV M L+EV+ + D + +
Sbjct: 427 VLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVR 486
Query: 202 SVGKTCITCKDTPGFVVKGS*LRTVLKR*GCTKEEMRQQKI 324
+ K + + PGF+V +L+ C +E + + +
Sbjct: 487 RLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEAV 527
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/90 (41%), Positives = 45/90 (50%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L PY EALR E G A E +D A+ + G PMGP+EL D GLD+ LA
Sbjct: 506 VLGPYMLEALRCVEEGVAP-EAVDAAL-VAFGMPMGPVELVDTVGLDI---ALAAGRALG 560
Query: 438 GNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
G V P + + LV G RK G G Y
Sbjct: 561 GGAVAVPKRLAE-LVAAGH-LGRKSGQGYY 588
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 55.6 bits (128), Expect = 7e-07
Identities = 25/81 (30%), Positives = 45/81 (55%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ PE I A+NTS++ + ++ R ++F G+HFF+PV M L+E+IK + +
Sbjct: 430 IIPEDCIFASNTSTLPITSLAEASVRPEQFIGIHFFSPVEKMFLVEIIKGEKTGDRAVAK 489
Query: 184 MMEWGKSVGKTCITCKDTPGF 246
+++ + + KT I D F
Sbjct: 490 ALDYVRQIRKTPIVVNDARFF 510
Score = 39.9 bits (89), Expect = 0.036
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Frame = +3
Query: 249 C*RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVML 428
C R + PY E RM G S ID A R G+P+GP++L D T +DL I
Sbjct: 512 CNRCIIPYINEGARMITEG-VSPVLIDNAARQ-LGFPVGPIQLTDETSIDLGAKIARATK 569
Query: 429 KETGNPVFE-PIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ E P L ++ RK G + Y+
Sbjct: 570 AAMGDAYPESPADDLIFWMEDQGRLGRKANAGFFDYD 606
>UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3;
Nitrosomonadaceae|Rep: 3-hydroxybutyryl-CoA epimerase -
Nitrosomonas eutropha (strain C71)
Length = 852
Score = 55.6 bits (128), Expect = 7e-07
Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 3/79 (3%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
ILA+NTS +S+N + + + + +F G+HFFNP M L+E+I + A+ +
Sbjct: 131 ILASNTSGLSINQLAAAVPEALRPRFCGIHFFNPPRYMYLVELIPGKQSDQGVLDALESF 190
Query: 196 -GKSVGKTCITCKDTPGFV 249
S+GK I KDTP FV
Sbjct: 191 LVTSLGKGVIHAKDTPNFV 209
>UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE)
(PBFE) [Includes: Enoyl-CoA
hydratase/3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (EC
4.2.1.17); 3- hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=28; Euteleostomi|Rep: Peroxisomal
bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA
hydratase/3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (EC
4.2.1.17); 3- hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Homo sapiens (Human)
Length = 723
Score = 55.6 bits (128), Expect = 7e-07
Identities = 32/80 (40%), Positives = 42/80 (52%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE L TNTS++ V+ I S R G HFF+P VM+LLEVI S + S T +M
Sbjct: 402 PE-AFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVM 460
Query: 190 EWGKSVGKTCITCKDTPGFV 249
K + K + + GFV
Sbjct: 461 NLSKKIKKIGVVVGNCFGFV 480
Score = 33.5 bits (73), Expect = 3.1
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL 401
R+L PY +A + E G + E++D + G+ MGP ++D GLD+
Sbjct: 483 RMLNPYYNQAYFLLEEG-SKPEEVDQVLE-EFGFKMGPFRVSDLAGLDV 529
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 54.8 bits (126), Expect = 1e-06
Identities = 27/82 (32%), Positives = 43/82 (52%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A I+ATNTS++ V+ + R G+HFF+P VMRLLEV++ + D
Sbjct: 394 VAKPGAIIATNTSTLDVDVLARATGRSADVVGMHFFSPAHVMRLLEVVRGAATAPDVLAT 453
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+M+ +GK + GF+
Sbjct: 454 IMKLAARIGKVPVVSGVCYGFI 475
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/93 (37%), Positives = 45/93 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P +A R+ E G A A +D MR G+ GPL AD G+D L V+ +
Sbjct: 240 RLLHPMINDAARVVESGTADAAAVDALMRDCLGHREGPLRTADLIGIDNLVDSLRVLRRR 299
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
TG+ EP +L V G RK G G Y Y
Sbjct: 300 TGDERCEPCDLLLAKVDAGH-LGRKSGRGFYDY 331
Score = 43.6 bits (98), Expect = 0.003
Identities = 23/80 (28%), Positives = 37/80 (46%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P T L +NTSSI + + + R G HF NP ++ +EV + S+ + +
Sbjct: 158 PPGTPLVSNTSSIPMGELAPALPRPGDLVGAHFMNPPYLIPAVEVARGPLTSDAAFAGLT 217
Query: 190 EWGKSVGKTCITCKDTPGFV 249
+G+ + D PGFV
Sbjct: 218 ALLARLGRAPVQVGDAPGFV 237
>UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family; n=1; Salinibacter ruber DSM
13855|Rep: 3-hydroxyacyl-CoA dehydrogenase, C-terminal
domain family - Salinibacter ruber (strain DSM 13855)
Length = 802
Score = 54.4 bits (125), Expect = 2e-06
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
A + +++TNTS + ++AI G K +F G HF+NP ++LLE++ +D D +
Sbjct: 128 AADDAVISTNTSGLPIHAITEGRSADFKRRFLGTHFYNPPRYLKLLELVPTDATDPDVTE 187
Query: 181 AMMEWGK-SVGKTCITCKDTPGFV 249
+ ++G+ +GK + D P F+
Sbjct: 188 RVAQFGRLRLGKGIVVANDVPYFI 211
Score = 33.9 bits (74), Expect = 2.4
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = +3
Query: 261 LAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD 398
L YSA R+ E D A D+D A+R G G+ MGP E+ D G++
Sbjct: 370 LLAYSAN--RLGEVSDNPA-DVDRAIRWGFGWTMGPFEMWDALGME 412
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 54.4 bits (125), Expect = 2e-06
Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P T +A+NTS++ ++ + + + + G+H+ P + R LE+I+ +H + T +
Sbjct: 107 LLPNSTPIASNTSALPISLLQAHCQLPQRIIGMHWAEPCHLTRFLEIIRGEHTDDATADS 166
Query: 184 MMEWGKSVGK-TCITCKDTPGFVV 252
G+ +GK I +D PGF+V
Sbjct: 167 AANLGRQLGKDPTIVQRDVPGFIV 190
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 54.4 bits (125), Expect = 2e-06
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
IL+TNTS+I + I + +K ++ G HFF+P VM+L E+I++D + K
Sbjct: 414 ILSTNTSTIDITKIAAKMKNPERIVGAHFFSPAHVMQLFEIIRTDATPAQILVDTLGLSK 473
Query: 202 SVGKTCITCKDTPGFVV 252
+ KT + + GF V
Sbjct: 474 QIKKTPVVVGNCTGFAV 490
>UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 710
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/76 (34%), Positives = 40/76 (52%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTS + ++ + + I R GLHFF+P VM+LLE++ +S D K
Sbjct: 414 VLATNTSYLDIDELAASIDRPADVIGLHFFSPANVMKLLEIVVPARVSADVVATAFALAK 473
Query: 202 SVGKTCITCKDTPGFV 249
+ KT + GF+
Sbjct: 474 QLKKTPVRAGVCDGFI 489
Score = 37.9 bits (84), Expect = 0.15
Identities = 32/93 (34%), Positives = 44/93 (47%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILA Y A + E G AS ID A+R G+PMGP ++ D G D+ +
Sbjct: 492 RILAVYRTAADYLMEDG-ASPYQIDRAVR-EFGFPMGPFQVVDLAGGDIGWA-TRKRRAA 548
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T +P + + D L +RG +K G Y Y
Sbjct: 549 TRDPRARYVEISDRLCERG-WFGQKTARGYYLY 580
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/78 (33%), Positives = 43/78 (55%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+ +L +NTS++ + + SG+ R F GLHFF+PV M L+E+I+ S+ +
Sbjct: 431 QDALLCSNTSTLPITELASGVDRPADFIGLHFFSPVDKMPLVEIIRGAKTSDVALAKAYD 490
Query: 193 WGKSVGKTCITCKDTPGF 246
+ + KT I D+ GF
Sbjct: 491 VVQQIRKTPIVVNDSRGF 508
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 53.6 bits (123), Expect = 3e-06
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY 177
L P+ I A+NTS +S+ + G+ + +F G+HFFNP M L+E+I +
Sbjct: 112 LRPD-AIFASNTSGLSIATLAEGLPEALRSRFCGVHFFNPPRYMALVELIPAPATDPLML 170
Query: 178 QAMMEW-GKSVGKTCITCKDTPGFV 249
A+ W +GK+ + KDTP FV
Sbjct: 171 DALEAWLVTRLGKSIVRAKDTPNFV 195
Score = 31.9 bits (69), Expect = 9.6
Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Frame = +3
Query: 282 ALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTG-LDLKKSI 413
A+ + E D SA DID AMR G G+ GP E G D+ K+I
Sbjct: 359 AVHLEEIAD-SARDIDLAMRWGFGWTRGPFETWQAAGWADVAKAI 402
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 53.6 bits (123), Expect = 3e-06
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
DL I+A+NTS + + I G + G H++NP +M L+EV++ + E +
Sbjct: 101 DLVNSECIIASNTSVLRITEIAEGSADPGRVVGTHWWNPPYLMPLVEVVRGELTREGVAK 160
Query: 181 AMMEWGKSVGKTCI-TCKDTPGFV 249
+ +W GKT + +D PGFV
Sbjct: 161 QVSQWLSKAGKTPVDVYRDVPGFV 184
Score = 36.7 bits (81), Expect = 0.34
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPM---GPLELADYTGLDLKKSIL 416
EA + E+G SAE +D RL G + GPL AD+ GLDL +IL
Sbjct: 195 EAAHIVEQGICSAETVDLVARLTFGRRLAAVGPLRNADFIGLDLTCAIL 243
>UniRef50_A3QGY2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Shewanella loihica (strain
BAA-1088 / PV-4)
Length = 708
Score = 53.6 bits (123), Expect = 3e-06
Identities = 26/76 (34%), Positives = 43/76 (56%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTS++ V+ I + R GLHFF+P VMRLLE+++++ + D ++ +
Sbjct: 409 ILATNTSTLDVDEIAAETSRPQDVLGLHFFSPANVMRLLEIVRANKTAPDALLTTVQLAQ 468
Query: 202 SVGKTCITCKDTPGFV 249
+ K + GF+
Sbjct: 469 RIKKVPVVSGVCWGFI 484
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 53.2 bits (122), Expect = 4e-06
Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+ A +LA+NTS+I + I G+ + + G H++NP V+ L+EV+ +
Sbjct: 138 ECARHDAVLASNTSAIPITQIAEGLPCEARIVGSHWWNPADVVPLVEVVPGIATDAHHVE 197
Query: 181 AMMEWGKSVGKTCITC-KDTPGFV 249
AMM+ SVGK + +D PGFV
Sbjct: 198 AMMQLLISVGKKAVRIDRDIPGFV 221
Score = 33.9 bits (74), Expect = 2.4
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAG---YPMGPLELADYTGLDLKKSILAVMLKETGNPV 449
EA + G AE +D ++ G +GP+E AD GLDL I+ V+L + N
Sbjct: 232 EAQSLVANGVCDAETLDEIVKSSFGPRLSVLGPMENADLIGLDLTLDIMRVILPDIDNSP 291
Query: 450 FEPIGVLDXLVKRGEXXDRKPGXG 521
EP +L V G+ K G G
Sbjct: 292 -EPGRLLTSRV-AGQHLGFKTGAG 313
>UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein; n=1; Lentisphaera
araneosa HTCC2155|Rep: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein - Lentisphaera araneosa
HTCC2155
Length = 762
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKD--KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
ILATNTS + + I + K +F G+HFFNP +LLE+I + + E+
Sbjct: 115 ILATNTSGLPLKDITKNLSNKSLKRFLGVHFFNPPRYQKLLELIPGPKTQDGLLEEFAEF 174
Query: 196 GK-SVGKTCITCKDTPGFV 249
+ +GK + KDTP F+
Sbjct: 175 ARLHLGKGIVVAKDTPNFI 193
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 52.4 bits (120), Expect = 6e-06
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+++ TNTS + V+ I G + + G HFFNP MRLLE+I + +A+
Sbjct: 118 SLITTNTSGLPVSKISEGFSEDFRRNWFGTHFFNPPRYMRLLELIPTPDTDPKAMEAVAH 177
Query: 193 WGK-SVGKTCITCKDTPGFV 249
G +GK + KDTP F+
Sbjct: 178 LGDVQLGKGIVHAKDTPNFI 197
Score = 33.1 bits (72), Expect = 4.2
Identities = 18/39 (46%), Positives = 23/39 (58%)
Frame = +3
Query: 282 ALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD 398
A R+ E D E ID AMR+G + MGP EL D G++
Sbjct: 370 ANRIPEISDTIVE-IDAAMRMGFNWEMGPFELWDAAGVE 407
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 52.4 bits (120), Expect = 6e-06
Identities = 26/76 (34%), Positives = 40/76 (52%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I TNTSS+ +N + S ++ K G+HFFNP ++R++EVI S E +
Sbjct: 149 IFGTNTSSLDLNEMSSVLRDPTKVVGIHFFNPANLIRMVEVIYGSKTSSKAVATAFEACR 208
Query: 202 SVGKTCITCKDTPGFV 249
S+ K + + P FV
Sbjct: 209 SIKKLPVLVGNCPAFV 224
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 52.0 bits (119), Expect = 8e-06
Identities = 25/76 (32%), Positives = 39/76 (51%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
++ +NTS + + + R D+F GLHFF PVPVM L+EV+ S T + +
Sbjct: 394 MVVSNTSYLDIAELARASGRPDRFLGLHFFAPVPVMTLVEVVPLPETSSHTLTVATQLVR 453
Query: 202 SVGKTCITCKDTPGFV 249
+GK + GF+
Sbjct: 454 DMGKVAVRAGPCNGFL 469
Score = 37.9 bits (84), Expect = 0.15
Identities = 31/94 (32%), Positives = 44/94 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI A Y E + E G A D+D +R G+ MGP ++ D +GLD+ + L
Sbjct: 472 RIYAAYRRECELLVEEG-AMPWDVDAELRK-QGFRMGPFQVGDLSGLDIGWA-LRRSRDA 528
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
T +P + D L + G RK G G Y Y+
Sbjct: 529 TRDPRERYFALPDTLYEMGR-LGRKSGAGWYAYS 561
>UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Deltaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 795
Score = 52.0 bits (119), Expect = 8e-06
Identities = 31/85 (36%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY 177
L P+ +L+TNTS +SVNA+ + + + HFFNP MRL+E++ S
Sbjct: 125 LRPD-AVLSTNTSGLSVNALAESLPEPLRPRLLVTHFFNPPRYMRLVELVSSRFTDRAVA 183
Query: 178 QAMMEWGK-SVGKTCITCKDTPGFV 249
M E + +GK ++ KDTP FV
Sbjct: 184 ARMAELLRVRLGKGVVSAKDTPNFV 208
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 51.6 bits (118), Expect = 1e-05
Identities = 23/71 (32%), Positives = 39/71 (54%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I ATNTS++ + + R ++F G+HFF+PV M L+E+IK + +++ +
Sbjct: 437 IFATNTSTLPITMLAKASSRAEQFIGIHFFSPVDKMALVEIIKGKQTGDVAVAKALDFVR 496
Query: 202 SVGKTCITCKD 234
+ KT I D
Sbjct: 497 QIRKTPIVVND 507
Score = 40.7 bits (91), Expect = 0.021
Identities = 23/53 (43%), Positives = 31/53 (58%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSI 413
R + PY E +RM + G A A I+ A +L G P+GPL+L D T +DL I
Sbjct: 515 RCILPYVNEGVRMLQEGVAPAL-IENAAKL-VGMPLGPLQLTDETSIDLGAKI 565
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 51.6 bits (118), Expect = 1e-05
Identities = 29/77 (37%), Positives = 44/77 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+ A S EA +M G ASAE+ID A++ G G PMGP+ A+ GL+ + ++ + K
Sbjct: 193 RMQALISNEAFKMLGEGLASAEEIDRALQQGLGLPMGPIAEAEQYGLERRLRMMEYLHKT 252
Query: 435 TGNPVFEPIGVLDXLVK 485
G + P +L+ VK
Sbjct: 253 LGE-TYRPAPLLEQYVK 268
Score = 31.9 bits (69), Expect = 9.6
Identities = 20/80 (25%), Positives = 39/80 (48%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE T++ ++T S+ + S I R K + F P LE+++ S++T A +
Sbjct: 112 PE-TMIVSHTQIQSITELASVIYRAPKCIAMWFPKPPQTSVALEIVRGLETSDETATAAV 170
Query: 190 EWGKSVGKTCITCKDTPGFV 249
+ + + I ++TPG +
Sbjct: 171 AVAQRMKREPILLRETPGAI 190
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 51.6 bits (118), Expect = 1e-05
Identities = 24/76 (31%), Positives = 41/76 (53%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTS ++ I GI ++F GLHFF+P VM+LLE++ + + + +
Sbjct: 154 VLATNTSYLNPERIADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPEALATGFALAR 213
Query: 202 SVGKTCITCKDTPGFV 249
+ K + + GF+
Sbjct: 214 MLNKIPVRAGISDGFI 229
Score = 40.3 bits (90), Expect = 0.027
Identities = 33/93 (35%), Positives = 42/93 (45%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL +A R+ G AS +D AMR G PMGP E D GLD+ + +
Sbjct: 232 RILKVMRGQAERLLVTG-ASPSAVDAAMR-AFGLPMGPFEAQDLGGLDI-AAFQRRAARA 288
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G PVF P+ + R +K G G Y Y
Sbjct: 289 RGLPVFAPVSDRLCAIAR---FGQKSGGGWYDY 318
>UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep:
Enoyl-CoA hydratase - Rhodopseudomonas palustris
Length = 699
Score = 51.2 bits (117), Expect = 1e-05
Identities = 24/76 (31%), Positives = 40/76 (52%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LA+NTS +S++ I + KR G+HFF+P VM+L E+++ + D + K
Sbjct: 405 VLASNTSYLSIDEIAATTKRPQDVLGMHFFSPANVMKLCEIVRGAKTAPDALLTAVSIAK 464
Query: 202 SVGKTCITCKDTPGFV 249
+ K + GFV
Sbjct: 465 KIAKVPVVVGVCDGFV 480
Score = 38.7 bits (86), Expect = 0.084
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASA-EDIDTAMRLGAGYPM---GPLELADYTGLDLKKSILAV 422
R++ P E R+ E A+ DID G G+P+ GP+ AD GL L+
Sbjct: 603 RMVYPMINEGARILEEKIAARPSDIDVVWLYGYGWPIYRGGPMHYADSVGLKHIAERLSA 662
Query: 423 MLKETGNPVFEPIGVLDXLVKRGE 494
K T +P EP +L L G+
Sbjct: 663 YAKATNDPSLEPAPLLARLAAEGK 686
>UniRef50_A3N0P8 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=1; Actinobacillus pleuropneumoniae
L20|Rep: Putative fatty acid oxidation complex alpha
subunit - Actinobacillus pleuropneumoniae serotype 5b
(strain L20)
Length = 705
Score = 51.2 bits (117), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E TI ATNTS+ ++ I + R + GLH+F+PV +++E+I E T +
Sbjct: 423 EQTIFATNTSTFAIKDIAACAIRPENVIGLHYFSPVTTQKMVEIIPHSATGEHTIATAIH 482
Query: 193 WGKSVGKTCITCKDTPGFVV 252
+ GK + D GF +
Sbjct: 483 FAIQQGKIPLLVADKQGFFI 502
Score = 36.7 bits (81), Expect = 0.34
Identities = 29/94 (30%), Positives = 46/94 (48%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P EA++ G+ S E ID +++ G+ +GPL + D GLD+ + ++ E
Sbjct: 504 RVLTPLLLEAVQCLIDGE-SIEFIDRSLQ-EFGFKLGPLAMIDEMGLDVLVKSNSALVSE 561
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ P V L+ R E K G Y Y+
Sbjct: 562 LGSRFSLPQAV--DLLFRNERKGCKNKRGFYMYD 593
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
LAP+ +LATNTS + + A+ ++ + G HF+NP ++ ++EV+ S + DT
Sbjct: 98 LAPD-AVLATNTSVLPIGAVTERVEDGSRVIGTHFWNPPDLIPVVEVVPSARTAPDTADR 156
Query: 184 MMEWGKSVGKTCITC-KDTPGFV 249
++ VGK + +D PGF+
Sbjct: 157 VVALLTQVGKLPVRVGRDVPGFI 179
Score = 32.7 bits (71), Expect = 5.5
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGY---PMGPLELADYTGLDLKKSILAVMLKETGNPV 449
EA+ + G + +D +R G +GPLE ADY GLDL +I ++ +
Sbjct: 190 EAIALVAEGVCDPKTVDLVVRNTIGLRLATLGPLENADYIGLDLTLAIHDAVIPSLNHDP 249
Query: 450 FEPIGVLDXLVKRGEXXDR 506
P +L LV G+ R
Sbjct: 250 -HPSPLLRELVAAGQLGAR 267
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 50.8 bits (116), Expect = 2e-05
Identities = 26/76 (34%), Positives = 40/76 (52%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTS + + +GI + GLHFF+P VM+LLE++K+ + + GK
Sbjct: 396 ILATNTSYLDPQLVFAGIANPARCLGLHFFSPAHVMKLLEIVKTPDTAPEVLATGFALGK 455
Query: 202 SVGKTCITCKDTPGFV 249
+ K + GF+
Sbjct: 456 RLRKISVLSGICDGFI 471
Score = 39.9 bits (89), Expect = 0.036
Identities = 23/49 (46%), Positives = 28/49 (57%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDL 401
R+LA Y EA + G A ++D AMR G PMGP EL D TGL +
Sbjct: 474 RMLAAYRREAEYLLADG-ALPHEVDAAMR-AQGLPMGPFELQDLTGLQI 520
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVI-KSDHISEDTYQA 183
E+ ILA+NTS +S+ + + K F G+HFFNP M L+E+I +D SE +
Sbjct: 225 ENAILASNTSGLSITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTNSEILDKL 284
Query: 184 MMEWGKSVGKTCITCKDTPGFV 249
+ +GK+ I KDTP F+
Sbjct: 285 ETFLVEKLGKSIIRAKDTPNFI 306
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 50.4 bits (115), Expect = 3e-05
Identities = 25/83 (30%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
LA T+LATNT+++SV AI R ++ H++ P ++ L+++I + S D +
Sbjct: 111 LAAPDTLLATNTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVET 170
Query: 184 MMEWGKSVGKT-CITCKDTPGFV 249
+ + + +GK+ + +D PG V
Sbjct: 171 VRRFIEELGKSPVVFSRDVPGSV 193
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 50.4 bits (115), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP+ +LA+ TS I V+ + R ++ GLHF NP P+ +EV++ S +
Sbjct: 112 APD-ALLASCTSGIPVDRLADTTTRPERVVGLHFMNPAPLKDTVEVVRGPRTSPQSLDRA 170
Query: 187 MEWGKSVGKTCITCKDTPGFVV 252
+ S+ KT I D PGF++
Sbjct: 171 LALLASLNKTGIVVGDGPGFLL 192
Score = 48.4 bits (110), Expect = 1e-04
Identities = 33/93 (35%), Positives = 42/93 (45%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L AEA G A AE D G+PMGPL AD GLD + + +
Sbjct: 194 RVLMLCIAEAAAALGDGIADAETTDALFEGCLGHPMGPLRTADLIGLDNVHDTMTALREL 253
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
TG+ + P L LV+ G RK G G + Y
Sbjct: 254 TGDDHYRPPESLVALVEAGH-LGRKTGRGFHEY 285
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I A+NTS+I + + D+F GLH+F+PV VM LLE++ SE T +++ +
Sbjct: 443 IWASNTSAIPIGDLAKVSAHADRFIGLHYFSPVEVMPLLEIVVGPETSERTLARCLDFCR 502
Query: 202 SVGKTCITCKDTPGF 246
+ K I D F
Sbjct: 503 RIKKLPIVVNDGYAF 517
>UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=6; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Roseiflexus sp. RS-1
Length = 807
Score = 50.0 bits (114), Expect = 3e-05
Identities = 30/82 (36%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFG----GLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
+I+++NTS I + AI +G R D F G HFFNP + LLEVI + A+
Sbjct: 129 SIVSSNTSGIPIAAIAAG--RSDDFRRHFLGTHFFNPPRYLYLLEVIPTPDTDPQVVAAI 186
Query: 187 MEWGK-SVGKTCITCKDTPGFV 249
+ ++GK + CKD P F+
Sbjct: 187 SRFADVTLGKGVVICKDRPNFI 208
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 50.0 bits (114), Expect = 3e-05
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
APE ILA+NTS +S I K ++ HF+NP + L+EV+ H T
Sbjct: 110 APE-VILASNTSGLSPTDIAINTKHPERVVIAHFWNPPQFIPLVEVVPGKHTDSKTVDIT 168
Query: 187 MEWGKSVGKTCITC-KDTPGFVVKGS*LRTVLKR 285
M+W + +GK + K+ GF+ G+ L+ L R
Sbjct: 169 MDWIEHIGKKGVKMRKECLGFI--GNRLQLALLR 200
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPM---GPLELADYTGLDLKKSILAVMLKETGNPV 449
EAL + E+G A+AE++D A+ G G + GP+ AD GLD+ +I + + K+ N
Sbjct: 201 EALYIVEQGFATAEEVDKAIEYGHGRRLPVTGPICSADLGGLDIFNNISSYLFKDLCNDT 260
Query: 450 FEPIGVLDXLVKRGEXXDRKPGXGIY 527
EP +L V G K G G Y
Sbjct: 261 -EPSKLLKSKVDGGNLGS-KTGKGFY 284
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 50.0 bits (114), Expect = 3e-05
Identities = 26/76 (34%), Positives = 39/76 (51%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
ILATNTS + I +G+ D+F LHFF+P VM+LLE++ + T
Sbjct: 400 ILATNTSYLDPERIVAGLPNPDRFIALHFFSPAQVMKLLEIVPLVATTSRTLATGFALAA 459
Query: 202 SVGKTCITCKDTPGFV 249
+GK + + GF+
Sbjct: 460 RLGKIPVQAGNGEGFI 475
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/93 (38%), Positives = 46/93 (49%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RIL Y AEA + G AS ++D AMR G+ MGP E+ D GLD+ +
Sbjct: 478 RILKRYRAEAEALLFAG-ASPSEVDQAMR-AFGFGMGPFEMQDMAGLDIAFRAREA-ARA 534
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
G+ + P G D LV+ G RK G G Y Y
Sbjct: 535 QGHDL--PEGPGDRLVRAGR-LGRKSGGGWYDY 564
>UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Solibacter usitatus
Ellin6076|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Solibacter usitatus (strain
Ellin6076)
Length = 778
Score = 49.6 bits (113), Expect = 4e-05
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDK--FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
IL+TNTS I + I +G + + F G HFFNP + L EVI +T +++W
Sbjct: 117 ILSTNTSGIPLAQISAGFDSEFRRHFLGTHFFNPPRYLHLAEVIP----GAETNPEVLDW 172
Query: 196 GKS-----VGKTCITCKDTPGFV 249
S +GK + CKDTP F+
Sbjct: 173 VSSFCDLHLGKGVVRCKDTPNFI 195
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/77 (32%), Positives = 41/77 (53%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
I+ +NTS+IS+ + + ++F G+HF NP P + +E+I S T A+ +
Sbjct: 130 IIGSNTSTISIADLSEPVTNPERFLGVHFSNPSPFIPGVEIIPHAGTSATTVGAVRDLVH 189
Query: 202 SVGKTCITCKDTPGFVV 252
+ GK KD GFV+
Sbjct: 190 AAGKQTAVVKDVTGFVL 206
Score = 37.9 bits (84), Expect = 0.15
Identities = 18/44 (40%), Positives = 29/44 (65%), Gaps = 3/44 (6%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMRLGAGYPM---GPLELADYTGLDL 401
EA ++ E+G A+A+D+DT +R G+ + GP +AD GLD+
Sbjct: 216 EAAQLVEQGIATADDVDTLVRTTFGFRLPFFGPFAIADMAGLDV 259
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 49.2 bits (112), Expect = 6e-05
Identities = 25/85 (29%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY 177
++PE ++ +NTS+I + + + + + +F H+FNPV MRLLE+++ +
Sbjct: 111 ISPE-CVVTSNTSTIPIKLLVEDMPQDFRARFAITHYFNPVRYMRLLELVRGADTNPAVM 169
Query: 178 QAMMEWGKSV-GKTCITCKDTPGFV 249
+ + + GK + C DTPGF+
Sbjct: 170 DRLARYNDEILGKGVVQCGDTPGFL 194
Score = 32.3 bits (70), Expect = 7.3
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +3
Query: 249 C*RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD 398
C L + A + + AS +DID AM+LG + GP E+ D D
Sbjct: 352 CRNFLGRVLSYAADLIPKVTASPQDIDDAMKLGFNWIRGPFEMIDALSAD 401
>UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Frankia alni
(strain ACN14a)
Length = 234
Score = 48.8 bits (111), Expect = 8e-05
Identities = 21/79 (26%), Positives = 38/79 (48%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A +LATN+S V A+ + R + G H+ +P +MR E++ ++H D
Sbjct: 98 VAAAGAVLATNSSGFPVGALAAATDRPTRVLGWHWSSPAQIMRFAEIVVTEHTDPDAVAT 157
Query: 184 MMEWGKSVGKTCITCKDTP 240
+ +GK + +D P
Sbjct: 158 VTRLAHGLGKNPVVVRDAP 176
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/77 (31%), Positives = 38/77 (49%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T+LATNTS + V+ + + + + GLHFF P +MRLLE++ S+
Sbjct: 391 TVLATNTSYLDVDVLAASTRDPSRILGLHFFAPAHIMRLLEIVTGAETSDRALATGYALA 450
Query: 199 KSVGKTCITCKDTPGFV 249
K + K + GF+
Sbjct: 451 KLLKKVPVLAGVCDGFI 467
Score = 35.1 bits (77), Expect = 1.0
Identities = 31/93 (33%), Positives = 42/93 (45%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI + Y EA + G A ++D AM GY MGP E+ D +GLD+ +
Sbjct: 470 RIFSRYKEEADILLMDG-AVPWEVDDAME-AFGYAMGPFEVGDLSGLDIGFANRR-RQDA 526
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T +P I + D +V G RK G Y Y
Sbjct: 527 TRDPNRRYIPIADRMVNEGR-LGRKASVGWYRY 558
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/91 (29%), Positives = 42/91 (46%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R+L P +A+R+ E+G + ED DT + G+P G +L D+ + M +
Sbjct: 193 RLLVPQMLDAVRLLEQGKITVEDGDTGLYTSLGHPQGTFKLHDFVTAPTMLRVALQMYQA 252
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY 527
+ +P P L +VK GE G G Y
Sbjct: 253 SNDPRMYPPLTLMRMVKNGE-YGASSGKGFY 282
Score = 37.1 bits (82), Expect = 0.26
Identities = 21/81 (25%), Positives = 38/81 (46%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P + +N+SS+ ++ + R D+ H NPVP+M +EV+ S +T +
Sbjct: 111 PPSVVFWSNSSSLDIDPMAQAGGRPDRSIVTHGMNPVPLMPGVEVVPGAKTSSETIEFTR 170
Query: 190 EWGKSVGKTCITCKDTPGFVV 252
+ ++ K + PGF V
Sbjct: 171 QTLLNMKKAPFLAPNIPGFWV 191
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGL--HFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+IL++NTS+I + A+ G+ L HFFNP MRLLE++ + + +
Sbjct: 107 SILSSNTSTIPLAALVGGMAGDFAADFLITHFFNPPRRMRLLELVAGPATRPEIVALITD 166
Query: 193 W-GKSVGKTCITCKDTPGFV 249
+ + +GK ++C+DTPGF+
Sbjct: 167 FCDRRLGKDVVSCRDTPGFI 186
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 48.4 bits (110), Expect = 1e-04
Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMR--LGAGYPM-GPLELADYTGLDLKKSILAVM 425
R A +EA RM E G AED+D + LG Y + GPL DY GLD+ +
Sbjct: 166 RFNAAVLSEASRMIEEG-VRAEDVDRVWKHHLGLLYTLFGPLGNLDYIGLDVAYYASLYL 224
Query: 426 LKETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
K G+ F+P L +K+GE K G GIY Y
Sbjct: 225 YKRFGDEKFKPPEWLQEKIKKGE-VGVKAGKGIYEY 259
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/69 (33%), Positives = 37/69 (53%)
Frame = +1
Query: 25 LATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS 204
L +NTS ISV+ I + +F G+H+ NP VM L+E++ S T + + +
Sbjct: 91 LCSNTSVISVDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRE 150
Query: 205 VGKTCITCK 231
+GK + CK
Sbjct: 151 LGKEVVVCK 159
>UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Haloarcula marismortui|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 290
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/81 (27%), Positives = 49/81 (60%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ + TI+A + +S+SV A+ +G++ D+ GL+ +P P ++EV+ ++ + T
Sbjct: 92 MVEDETIIAVSDTSLSVTAVATGLRSPDRAVGLNLVDP-PDGAIVEVVIAEQTTAATRDR 150
Query: 184 MMEWGKSVGKTCITCKDTPGF 246
+ ++ +S+ + + +DTPGF
Sbjct: 151 VTDFVESLDASPVVVRDTPGF 171
Score = 35.5 bits (78), Expect = 0.78
Identities = 29/84 (34%), Positives = 36/84 (42%)
Frame = +3
Query: 276 AEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKETGNPVFE 455
AEA+RM E G A DID G GPL AD GL+ + L + K + F
Sbjct: 182 AEAIRMVEDGVAGIRDIDRTFERGESDRDGPLVRADRHGLETVLTALEDLSKRL-DERFA 240
Query: 456 PIGVLDXLVKRGEXXDRKPGXGIY 527
P +L V G+ G G Y
Sbjct: 241 PPALLRQKVADGQ-RGAVTGEGFY 263
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/83 (28%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L + TI+A++TS I + + + I ++ G+H+ NP ++ ++EVI + + T
Sbjct: 104 LIGQDTIVASDTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVAT 163
Query: 184 MMEWGKSVG-KTCITCKDTPGFV 249
+ + +S+G + KD PGFV
Sbjct: 164 IRDLIRSIGLLPVVVKKDVPGFV 186
Score = 45.6 bits (103), Expect = 7e-04
Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYP---MGPLELADYTGLDLKKSILAVM 425
R+L EA+ + ERG ED+DT + G GY +GP+ L D GLD+ KS+ + +
Sbjct: 189 RVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMALLDMAGLDIYKSVSSFL 248
Query: 426 LKETGN 443
+ N
Sbjct: 249 NADLSN 254
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 47.6 bits (108), Expect = 2e-04
Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 4/85 (4%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVI---KSD-HISEDT 174
AP+ IL+TNTS +S A+ S + ++F HF+NP +M L+EV+ K+D + + T
Sbjct: 115 APKDAILSTNTSGLSPTALQSVMGHPERFVVAHFWNPAQLMPLVEVVPGEKTDPKVVDIT 174
Query: 175 YQAMMEWGKSVGKTCITCKDTPGFV 249
+ M + GK K K++ GFV
Sbjct: 175 FDLMAKIGKKPAK---IKKESLGFV 196
>UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; Streptococcus agalactiae|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Streptococcus agalactiae
serotype Ia
Length = 377
Score = 47.6 bits (108), Expect = 2e-04
Identities = 22/53 (41%), Positives = 31/53 (58%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL 416
IL P+ AL +Y + +E ID +LG G PMGPLE+ D G+D +I+
Sbjct: 282 ILVPFLESALALYYDKVSDSETIDKTWKLGTGAPMGPLEILDIIGIDTAYNIM 334
Score = 42.3 bits (95), Expect = 0.007
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP TI ATN+S++ + R DKF +HF N + ++E++ ++ +
Sbjct: 196 VAPSKTIFATNSSTLVPSQFADITGRPDKFLAMHFANNIWQNNIVEIMGHKGTDDEVIKE 255
Query: 184 MMEWGKSVGKTCITC-KDTPGFVV 252
+ + K +G + K+ PG+++
Sbjct: 256 ALTFSKDIGMVPLHIHKEQPGYIL 279
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/87 (27%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ PE+ +LATNTSS ++ I + + RK++ G+H+ P ++ ++E+I + DT
Sbjct: 114 ICPENVVLATNTSSFLISDIAAQMTRKERMMGIHYVTPGHIVPVIELIH----AADTPAE 169
Query: 184 MMEWGK----SVGKTCITCKDTPGFVV 252
++ W + ++ + + PGF+V
Sbjct: 170 LVAWSRMLVQNIEHVGVAILERPGFLV 196
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 47.6 bits (108), Expect = 2e-04
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A +LA+NTS +SV AI + R ++ HF+NP ++ L+E+I+ S A
Sbjct: 103 VARADAVLASNTSGLSVTAIAAECARPEQVLATHFWNPPHLVPLVEIIQGRATSPAAAAA 162
Query: 184 MMEWGKSVGKTCITCK-DTPG 243
+ E + GKT + K D PG
Sbjct: 163 VRELLTACGKTPVVVKLDRPG 183
>UniRef50_UPI00006A2DC9 Cluster: UPI00006A2DC9 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A2DC9 UniRef100 entry -
Xenopus tropicalis
Length = 622
Score = 47.2 bits (107), Expect = 2e-04
Identities = 35/93 (37%), Positives = 47/93 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RILA Y A + E G AS +ID A+R G GYPMGP ++ D G D+ +
Sbjct: 414 RILAVYKQAADYLMEDG-ASPYEIDAAVR-GFGYPMGPFQVTDLAGGDIGWA-TRKRRAA 470
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
T +P + V D + +RG +K G G Y Y
Sbjct: 471 TRDPKARYVEVADRICERG-WFGQKTGRGFYLY 502
>UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1;
Clostridium acetobutylicum|Rep: 3-Hydroxyacyl-CoA
dehydrogenase - Clostridium acetobutylicum
Length = 379
Score = 47.2 bits (107), Expect = 2e-04
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY-Q 180
+ + ILATNTSSI + + + +K++ GLHFF PV ++ +E I +E Y +
Sbjct: 104 IVKDECILATNTSSIPLEIVFAKCVKKERCLGLHFFFPVKIIDFVE-INELRCTESRYVE 162
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
++++ ++GKT + + FV+
Sbjct: 163 TIVQFLTTIGKTSLDLDEKSNFVL 186
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
A +LA+N++S ++ I SG+K + GLHFF P ++ +EV+ + S ++
Sbjct: 105 AKPEAVLASNSTSFPISEIASGLKTAARMIGLHFFMPAHLVPCVEVVYGEKTSPMVGDSL 164
Query: 187 MEWGKSVGKTCITC-KDTPGFV 249
+ G +T KD PGF+
Sbjct: 165 SRLMTACGMVPVTVKKDLPGFL 186
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 46.8 bits (106), Expect = 3e-04
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIK---SDHISEDTYQAMM 189
TI+A+ TS+I V+ + I +F +H+ NP ++ L+EV +D D +A++
Sbjct: 123 TIIASTTSTILVDDLSGAIVNPHRFLNVHWLNPAYLIPLVEVSPGKATDPAIIDEVKALL 182
Query: 190 EWGKSVGKTCITCKDTPGFVV 252
E +GK + C TPGF+V
Sbjct: 183 E---GIGKVPVVCAATPGFIV 200
Score = 40.3 bits (90), Expect = 0.027
Identities = 25/52 (48%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGY---PMGPLELADYTGLDL 401
RI A EA RM E G ASAE+ID A+R G G+ +G LE D+ G D+
Sbjct: 202 RIQALAMNEAARMVEEGVASAEEIDKAIRYGFGFRYAVLGLLEFIDWGGGDI 253
>UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=2;
Cystobacterineae|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Stigmatella aurantiaca DW4/3-1
Length = 797
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Frame = +1
Query: 22 ILATNTSSISVNAI--GSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
I+++NTS +S+ + G G + + +F HFFNPV M+LLE++ + + +
Sbjct: 126 IVSSNTSGLSIAGMLQGRGPEFRKRFLVTHFFNPVRYMKLLELVAGPETDPAVVRTLHAF 185
Query: 196 GKSV-GKTCITCKDTPGFV 249
G+ V GK + KDT F+
Sbjct: 186 GEGVLGKGIVYGKDTTNFI 204
>UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 794
Score = 46.8 bits (106), Expect = 3e-04
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW 195
IL TNTS + V I + + + ++ G HFFNP MRLLE+I + A+ +
Sbjct: 136 ILTTNTSGLPVAQIAAKLPADVRRRWFGTHFFNPPRYMRLLEIIPTPDADAAAIAAISHF 195
Query: 196 GK-SVGKTCITCKDTPGFV 249
+GK + +DTP F+
Sbjct: 196 ADVLLGKEVVFARDTPNFI 214
>UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Possible
3-hydroxybutyryl-CoA dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 331
Score = 46.4 bits (105), Expect = 4e-04
Identities = 21/67 (31%), Positives = 37/67 (55%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PEHT++ATN+S++ + R +K+ LHF N + + +E++ + DT A
Sbjct: 120 PEHTMIATNSSTLLPQDFAAATGRPEKYCALHFANLIWKLNAVEIMAHPETARDTLIAAT 179
Query: 190 EWGKSVG 210
E+G +G
Sbjct: 180 EFGIEIG 186
>UniRef50_Q7UXV2 Cluster: Fatty oxidation complex alpha subunit;
n=1; Pirellula sp.|Rep: Fatty oxidation complex alpha
subunit - Rhodopirellula baltica
Length = 396
Score = 46.0 bits (104), Expect = 6e-04
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKD-KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
IL TNTS++ + I ++ +F G+HFF PV E+I SE +A
Sbjct: 119 ILTTNTSTLPITEIAGAMRTHSARFCGMHFFMPVVGRHAAEIIVHSRTSEAVIEACEGHV 178
Query: 199 KSVGKTCITCKDTPGFVV 252
+ + K + D+PGFVV
Sbjct: 179 RRLKKAPLRVLDSPGFVV 196
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 46.0 bits (104), Expect = 6e-04
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Frame = +1
Query: 13 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
E T +A+NTS+ + + + + + HFFNP V+ L+EV+ S D A+
Sbjct: 88 ESTPIASNTSTFTPSELAKNLCEPGRLVIAHFFNPAEVVPLVEVVPSPDTRPDVVSAVTS 147
Query: 193 WGKSVGKTCITC-KDTPGFV 249
+ GKT + ++ PGFV
Sbjct: 148 ALVAAGKTVVPLNREAPGFV 167
>UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Corynebacterium efficiens|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 755
Score = 45.6 bits (103), Expect = 7e-04
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGS--GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
+++++NTS+I + + G + F +HFFNP MRL+E++ + T +
Sbjct: 121 SLVSSNTSTIPLAQLTEVMGTPMRLDFAIVHFFNPPTTMRLVELVTGPDTTPKTATDLTR 180
Query: 193 -WGKSVGKTCITCKDTPGFV 249
+ +GK + C+DTPGF+
Sbjct: 181 IIEQQLGKVVLHCRDTPGFI 200
Score = 37.9 bits (84), Expect = 0.15
Identities = 17/35 (48%), Positives = 23/35 (65%)
Frame = +3
Query: 312 SAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSIL 416
+ E+ID AM+LG G+ GP LAD GLD + +L
Sbjct: 363 TVEEIDLAMQLGYGWKKGPFALADDIGLDTLRELL 397
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 45.6 bits (103), Expect = 7e-04
Identities = 21/76 (27%), Positives = 39/76 (51%)
Frame = +1
Query: 25 LATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS 204
+A+ TS+ V + + R ++ H+ NP +M L+E+ +SD + A+ +
Sbjct: 128 IASTTSTFVVTELQRHVVRPERMLNAHWLNPALLMPLVEISRSDATDQSVVDALAALLER 187
Query: 205 VGKTCITCKDTPGFVV 252
VGK + C PG++V
Sbjct: 188 VGKKPVICGPAPGYIV 203
Score = 45.6 bits (103), Expect = 7e-04
Identities = 37/96 (38%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAG---YPMGPLELADYTGLDLKKSILAVM 425
RI A EA RM E G ASAEDIDTA+R G G +G LE D+ G D+ +
Sbjct: 205 RIQALAMNEAARMVEEGVASAEDIDTAIRTGFGPRFAVLGLLEFIDWGGCDILYYASKYL 264
Query: 426 LKETGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
E G P F P + ++ G R G G + Y
Sbjct: 265 AGEIG-PRFAPAASVVRNMETGRDGVR-TGAGFHDY 298
>UniRef50_A3K5J4 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=1; Sagittula stellata E-37|Rep:
Putative fatty acid oxidation complex alpha subunit -
Sagittula stellata E-37
Length = 673
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/93 (33%), Positives = 46/93 (49%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
R++A Y EA+ M + G D+D A LG G P+GP+ LAD GLD + +
Sbjct: 487 RLVAAYLMEAMVMIDEGH-DKRDLDRAA-LGFGMPVGPVALADRMGLDRCLKLFNAVTDT 544
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
+ +PV L +V+ G + G G+Y Y
Sbjct: 545 SDSPVASIPAWLPEMVEDGH-TGIEAGTGLYLY 576
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 44.4 bits (100), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L + ILA+NTS + + + ++ KD+F HF+NP ++ L+EV+ + + Q
Sbjct: 120 LLADDAILASNTSGFHPDQLAAPLRAKDRFVIAHFWNPPHMIPLVEVVPGTATAPEVTQQ 179
Query: 184 MMEWGKSVG-KTCITCKDTPGFV 249
++G + + K PGFV
Sbjct: 180 TAALMSAIGMEPVVLAKAIPGFV 202
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ P+ TILAT S SV+ + + +K++D+ HF+ P ++ L+EV + S+ T
Sbjct: 111 ICPQDTILAT-ASGHSVSEVIAQVKKRDRVIATHFWFPPQLLPLVEVCGAPETSKATIDT 169
Query: 184 MMEWGKSVGKTCITC-KDTPGFV 249
E K +GK + K+ GF+
Sbjct: 170 TCELLKGIGKKPVVIDKEIDGFI 192
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 44.0 bits (99), Expect = 0.002
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
+LATNTSS + I + ++ HF NP +M L+EV + +S++T + +E K
Sbjct: 108 VLATNTSSFMPSEIARHLANPERLTLFHFSNPPILMPLVEV-GGEIVSDETVERAVEMAK 166
Query: 202 SVGKTCITC-KDTPGFVV 252
S+GK + K+ G V+
Sbjct: 167 SIGKEPVVLRKECRGHVL 184
>UniRef50_A5ULU2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, FadB;
n=3; cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase, FadB - Methanobrevibacter smithii (strain
PS / ATCC 35061 / DSM 861)
Length = 318
Score = 44.0 bits (99), Expect = 0.002
Identities = 22/82 (26%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
PE TI+ATN+S++ +A R +K+ LHF N + E++ ++ Y A+
Sbjct: 142 PEKTIIATNSSTMLPSAFAQYTGRPEKYLALHFANEIWRNNTAEIMGHPDTGQEYYDAVC 201
Query: 190 EWGKSVGKTCITC-KDTPGFVV 252
E+ +++ + K+ PG+++
Sbjct: 202 EFAENINMIPLKLKKEQPGYIL 223
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 43.6 bits (98), Expect = 0.003
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGI-KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+A TILAT+TS +S++ I + K ++ H +NP ++ L+EV+ E +
Sbjct: 107 IAEPETILATSTSGLSISEIQTAARKHPERCITAHPYNPPHLIPLVEVVPRKQTDESCTE 166
Query: 181 AMMEWGKSVGKTCITC-KDTPGFV 249
+E+ + +GK I KD PG V
Sbjct: 167 KTVEFMERMGKKPIVVKKDVPGMV 190
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 42.7 bits (96), Expect = 0.005
Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +1
Query: 10 PEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 189
P+ TI +TN S + + I R D+F LHF PV V L +V+ S + + +
Sbjct: 112 PQRTIFSTNASLLVPSQIAKATGRPDRFLALHFHQPVWVGNLADVMPHAGTSSEVVKVVH 171
Query: 190 EWGKSVGK-TCITCKDTPGFV 249
++ KS+ + + K+ G+V
Sbjct: 172 DFAKSINQIPLVLNKENFGYV 192
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 42.7 bits (96), Expect = 0.005
Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGL---HFFNPVPVMRLLEVIKSDHISEDTY 177
AP +LA+++S I +AI + D G L H FNP V+ L+E++ + E
Sbjct: 95 APPRAVLASSSSGIVASAIAEHLP-DDVAGRLLIAHPFNPPQVVPLVEIVPGERTEERVT 153
Query: 178 QAMMEWGKSVGKTCITC-KDTPGFV 249
+A + ++GKT + K+ PGFV
Sbjct: 154 EAATAFYTALGKTPVRLRKEVPGFV 178
>UniRef50_Q586V7 Cluster: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative;
n=3; Trypanosoma|Rep: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative -
Trypanosoma brucei
Length = 803
Score = 42.7 bits (96), Expect = 0.005
Identities = 26/84 (30%), Positives = 39/84 (46%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
DL P H +LAT SS+ + +R +K G++F PV + LEV + T Q
Sbjct: 457 DLCPPHCVLATCCSSLELREFVKVSRRPEKVVGMYFAPPVHNVPFLEVTRGYRTDHTTLQ 516
Query: 181 AMMEWGKSVGKTCITCKDTPGFVV 252
+ G+ K I +D GF +
Sbjct: 517 RAIHVGRLFHKATILTRDV-GFSI 539
>UniRef50_A3VIL7 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacterales bacterium HTCC2654
Length = 695
Score = 41.9 bits (94), Expect = 0.009
Identities = 17/70 (24%), Positives = 34/70 (48%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+A HTI A++T+ + + R D+F +HF P RL+E+ + +
Sbjct: 403 VAAGHTIFASSTAECDIETLAGASGRPDRFAAMHFIAPADANRLVEIAPARGTRPEALMT 462
Query: 184 MMEWGKSVGK 213
++ +++GK
Sbjct: 463 LIRLARAMGK 472
Score = 35.5 bits (78), Expect = 0.78
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +3
Query: 321 DIDTAMRLGAGYPM---GPLELADY-TGLDLKKSILAVMLKETGNPVFEPIGVLDXLVKR 488
DID M LG G+P GP+ AD T L+++K L+ E NP + P+ + D LVK
Sbjct: 629 DIDAVMLLGLGFPREKGGPMLAADLATPLEVRKD-LSDWASE--NPFWAPVPLWDELVKH 685
Query: 489 G 491
G
Sbjct: 686 G 686
Score = 33.9 bits (74), Expect = 2.4
Identities = 19/48 (39%), Positives = 27/48 (56%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLD 398
R+ Y A A + E+G AE +D AMR G G P+GP + D G++
Sbjct: 487 RMRQAYYAAAALVVEQGALPAE-VDLAMR-GYGMPLGPFQAQDVAGIE 532
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 41.5 bits (93), Expect = 0.012
Identities = 19/85 (22%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++A +TI ATN+S++ + R +KF LHF N + E++++ + +
Sbjct: 158 EVADPNTIFATNSSTLLPSQFMEETGRPEKFLALHFANEIWKFNTAEIMRTPRTDDAVFD 217
Query: 181 AMMEWGKSVGKTCITC-KDTPGFVV 252
++++ K +G + K+ G+++
Sbjct: 218 TVVQFAKDIGMVALPMYKEQAGYIL 242
>UniRef50_A4FJS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 659
Score = 40.7 bits (91), Expect = 0.021
Identities = 21/75 (28%), Positives = 38/75 (50%)
Frame = +1
Query: 25 LATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS 204
LATNTS + ++A+ + ++ G+HF P +LEV++ S+D ++ +
Sbjct: 378 LATNTSYLDIDALAATAADPERVLGMHFLAPAHRTGVLEVVRGRATSQDALDHVLSAARL 437
Query: 205 VGKTCITCKDTPGFV 249
+GK + GFV
Sbjct: 438 LGKLPVIVGVCDGFV 452
Score = 33.1 bits (72), Expect = 4.2
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI + Y + + E G A+ +D A+ L G MGP +AD +GLD+ + A ++
Sbjct: 455 RIFSAYRHQCELLVEEG-ATPRQVDEAL-LDVGVAMGPFAVADMSGLDV--AWHARRRRD 510
Query: 435 TGNPVFEPIGVL-DXLVKRGEXXDRKPGXGIY*Y 533
E L D LV++G +K G G Y Y
Sbjct: 511 AARDPRERYSDLADRLVEKGR-LGQKTGAGWYRY 543
>UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Leptospira interrogans
Length = 436
Score = 39.9 bits (89), Expect = 0.036
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Frame = +3
Query: 324 IDTAMRLGAGYPMGPLELADYTGLDLKKSI---LAVMLKETGNPVFEPIGVLDXLVKRGE 494
+D M G M PL+ AD+ GLD+ K+I L M K+ + F+ L+ +G+
Sbjct: 214 MDAIMSGYTGRAMAPLDTADFVGLDVHKAIVDNLYEMTKDAAHSTFKMPDYFQKLIDKGD 273
Query: 495 XXDRKPGXGIY 527
RK G G+Y
Sbjct: 274 -LGRKTGGGLY 283
Score = 35.9 bits (79), Expect = 0.59
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDK--FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 192
TI++T +S +S+ + + + G HFFNP M L E++ + + + E
Sbjct: 107 TIVSTVSSGLSIERLSKAFDEDGQKHYFGTHFFNPPYKMILCELVSHKGSDKKVLKQLGE 166
Query: 193 W-GKSVGKTCITCKDTPGF 246
+ K +G+ + DTP F
Sbjct: 167 YLEKVLGRAVVYTNDTPAF 185
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 39.9 bits (89), Expect = 0.036
Identities = 20/85 (23%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
+LAPE TI A+N+S+ + + R +KF +HF N + ++E++ + S + +
Sbjct: 103 ELAPEKTIFASNSSTFIPSQLAPYTDRPEKFLNMHFANQIWKFNVVEIMGTSQTSPEVIE 162
Query: 181 AMMEWGKSVGKT-CITCKDTPGFVV 252
++ + + I K+ G+++
Sbjct: 163 EATKFAREIKMVPVILNKEQHGYIL 187
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 39.9 bits (89), Expect = 0.036
Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P HT++ATN+S+ + + R DKF LH+ N + L+E++ + T
Sbjct: 110 LLPAHTLIATNSSTFLPSDFAAATGRPDKFCALHYANYIWAANLVEIMPHAATARTTLDD 169
Query: 184 MMEWGKSVGKTCITC-KDTPGFVV 252
+ + G I K+ G+V+
Sbjct: 170 VTRFAIETGMVPIPVGKEHNGYVL 193
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 39.5 bits (88), Expect = 0.048
Identities = 24/43 (55%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 279 EALRMYERGDASAEDIDTAMR--LGAGYPM-GPLELADYTGLD 398
EAL + G ASAE +D MR LG Y M GPLE AD GLD
Sbjct: 200 EALHIVRSGAASAETVDRVMRASLGRRYAMVGPLEAADMGGLD 242
Score = 36.7 bits (81), Expect = 0.34
Identities = 18/78 (23%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +1
Query: 19 TILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG 198
T++A+NTS + +A+ G++ ++ HF+NP ++ L+E++ + +A+
Sbjct: 112 TVIASNTSGLPPDALAEGMRHPERLLIAHFWNPPHLIPLVEIVPGSATRAEHLEAVRTLL 171
Query: 199 KSVG-KTCITCKDTPGFV 249
+ + + K PGF+
Sbjct: 172 AGMELEAVVLDKAIPGFI 189
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 39.5 bits (88), Expect = 0.048
Identities = 22/76 (28%), Positives = 38/76 (50%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+ PE TI TNTSS+ + + R D+F HF P +L++V+ S +T +
Sbjct: 111 VCPERTIFTTNTSSLVPSMFAARTGRPDRFLAFHFH---PGFKLVDVMGHAGTSAETVET 167
Query: 184 MMEWGKSVGKTCITCK 231
+ + + +G + I K
Sbjct: 168 VRRFAERIGHSPIVLK 183
Score = 37.1 bits (82), Expect = 0.26
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Frame = +3
Query: 258 ILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKET 437
+L P+ L + R A+ ED+D A P+GP L D+ GL+ I ++
Sbjct: 194 LLNPWLLAGLNLVSREIAAPEDVDRAWTEITAMPLGPFALMDFIGLETVWRITDFWARKR 253
Query: 438 GNP-VFEPIGVLDXLVKRGEXXDRKPGXGIY*YN 536
G+ + +L V RG K G G + Y+
Sbjct: 254 GDANAQKSADLLKQYVDRGH-LGMKTGKGFFNYS 286
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 39.5 bits (88), Expect = 0.048
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQ 180
++A TILA++TS+I + G+ K++ +H NP + L E++ + S+DT
Sbjct: 78 EIADPTTILASSTSTIPASKFTDGLINKERCLIVHPVNPPLFLPLTELVPAPWTSQDTVD 137
Query: 181 AMMEWGKSVGKTCITC-KDTPGFVV 252
E +SV + + K+ GFVV
Sbjct: 138 RAAEIMRSVKQEPVKLKKEVLGFVV 162
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 39.5 bits (88), Expect = 0.048
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP +L ++TS I + ++ K + +H +NP +M LLE++ S S+
Sbjct: 104 APNDALLWSSTSGIPASQQAQDMQDKTRLLVVHPYNPPHIMPLLELVPSSETSDTVISRT 163
Query: 187 MEWGKSVGKTCITCK-DTPGFV 249
++ + G+ I K +T GFV
Sbjct: 164 QDFWRERGRVPIHIKRETTGFV 185
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 39.1 bits (87), Expect = 0.063
Identities = 23/80 (28%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGIKRKDKFGGL---HFFNPVPVMRLLEVIKSDHISED 171
+L TI+AT++S ++ ++I G++ + K + H FNP ++ L+EV+ + S+
Sbjct: 106 NLVDPDTIIATSSSGLTCSSIQQGLEAQHKPERVVVGHPFNPPHLIPLVEVVGGEQTSQA 165
Query: 172 TYQAMMEWGKSVGKTCITCK 231
T M + + VGK + K
Sbjct: 166 TISRTMGFYEEVGKKAVHIK 185
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 38.7 bits (86), Expect = 0.084
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGL--HFFNPVPVMRLLEVIKSDHISEDTYQ 180
AP+ I AT++S+I + I + + + H FNP +M L+EV+ + S DT +
Sbjct: 103 APKDAIFATSSSTIPASLIARHLPPEVAARVIVGHPFNPPHLMPLVEVVPAPATSSDTVE 162
Query: 181 AMMEWGKSVGKTCITC-KDTPGFV 249
+E+ +S G+ + ++ GFV
Sbjct: 163 RALEFYRSCGREPVALNREVRGFV 186
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 38.7 bits (86), Expect = 0.084
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L IL +NTS+ ++ I + ++ H+FNP +M L+EV+ S++T
Sbjct: 109 LCASDCILCSNTSASNIFEIAP-VSHPERQIITHYFNPPFIMDLVEVVMGPKTSDETLDK 167
Query: 184 MMEWGKSVGKTCITCKD-TPGFVV 252
+ + VGK K PGF+V
Sbjct: 168 VKSFLIQVGKEPAVLKQYIPGFIV 191
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 38.3 bits (85), Expect = 0.11
Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
L P TILA++TS + + + + + + H NP ++ ++E+ S+ + +
Sbjct: 117 LTPPETILASSTSGLMASQFSAHLAGRHRALVAHPVNPPHLVPVVEISPSEWTDPEIVRV 176
Query: 184 MMEWGKSVGKTCITC-KDTPGFVV 252
+++ VG+T +T K+ PGF++
Sbjct: 177 VVDVMTGVGQTPVTVQKEIPGFLL 200
>UniRef50_A2QI39 Cluster: Similarity to hypothetical
3-hydroxyacyl-CoA-dehydrogenase hcd - Gibberella zeae
precursor; n=1; Aspergillus niger|Rep: Similarity to
hypothetical 3-hydroxyacyl-CoA-dehydrogenase hcd -
Gibberella zeae precursor - Aspergillus niger
Length = 260
Score = 38.3 bits (85), Expect = 0.11
Identities = 28/93 (30%), Positives = 40/93 (43%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI A E L + E G A+ E++D + P GP EL D GLD+ ++ K
Sbjct: 168 RIWAAIKRETLLVLEEGIATPEEVDQIYKCVLKTPRGPCELMDIAGLDVILAVEEHYAKV 227
Query: 435 TGNPVFEPIGVLDXLVKRGEXXDRKPGXGIY*Y 533
P L ++ RG+ K G G + Y
Sbjct: 228 RMGIPNAPRKYLREMIDRGD-LGVKSGNGFFSY 259
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 38.3 bits (85), Expect = 0.11
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
Frame = +1
Query: 4 LAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 183
+AP L T+TS I+ + + ++ K + +H FNP +M LLE++ + S + +
Sbjct: 124 VAPPSAHLWTSTSGIAASIQQAKMQDKTRLLVVHPFNPPNIMPLLEIVPAPGTSAERVEF 183
Query: 184 MMEWGKSVG---KTCITCKDTPGFVVKGS*LRTVLKR*GC 294
E+ G + + K+ PGFV G+ L L R C
Sbjct: 184 AREYFSLPGSRHRPVVIQKEIPGFV--GNRLAFALLREAC 221
>UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Symbiobacterium
thermophilum
Length = 190
Score = 37.9 bits (84), Expect = 0.15
Identities = 20/62 (32%), Positives = 32/62 (51%)
Frame = +1
Query: 7 APEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAM 186
AP H ILAT + +IS + + R D+ L FF+P + VI+ H++ + A+
Sbjct: 107 APAHAILATCSPTISSAYLAAATSRPDRVVSLGFFSPPLAPPAVAVIQEPHLAPEVVAAV 166
Query: 187 ME 192
E
Sbjct: 167 AE 168
>UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Aurantimonas sp. SI85-9A1|Rep:
Putative 3-hydroxybutyryl-CoA dehydrogenase -
Aurantimonas sp. SI85-9A1
Length = 286
Score = 37.9 bits (84), Expect = 0.15
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +1
Query: 22 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 201
++A+NTS + + I + R D F G+H+F+P + ++E ++ + T + +
Sbjct: 87 LMASNTSGLPLQDIADRLARPDLFLGIHWFHPADELPMVESVRVAETAPATVDTALALLR 146
Query: 202 SVG-KTCITCKDTPGFVV 252
+ G + + + PG VV
Sbjct: 147 AAGWDSIVVPRPVPGAVV 164
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 37.9 bits (84), Expect = 0.15
Identities = 24/62 (38%), Positives = 31/62 (50%)
Frame = +3
Query: 255 RILAPYSAEALRMYERGDASAEDIDTAMRLGAGYPMGPLELADYTGLDLKKSILAVMLKE 434
RI A EAL + E G ASAE+ID + GP E+ D GLD +I ++E
Sbjct: 201 RIWAAIKREALLVMEEGVASAEEIDDLFKGWFQAQAGPCEMIDRVGLDTVYNIEKHYVEE 260
Query: 435 TG 440
G
Sbjct: 261 RG 262
>UniRef50_Q5T751 Cluster: Late cornified envelope protein 1C; n=39;
Mammalia|Rep: Late cornified envelope protein 1C - Homo
sapiens (Human)
Length = 118
Score = 37.1 bits (82), Expect = 0.26
Identities = 15/31 (48%), Positives = 17/31 (54%)
Frame = -1
Query: 250 QRILECPYK*CKSCPQTCPTPSWPGKCPRKC 158
Q+ + P K CP CPTP P KCP KC
Sbjct: 7 QQQCQPPPKCTPKCPPKCPTPKCPPKCPPKC 37
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 36.3 bits (80), Expect = 0.45
Identities = 22/85 (25%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 1 DLAPEHTILATNTSSISVNAIGSGI-KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY 177
D+ P H +A+++S + ++ I + K ++ H FNP ++ L+E++ D S+D
Sbjct: 97 DVLPAHVPIASSSSGLKMSDIQTACDKHPERCLIAHPFNPPHLIPLVELVGGDATSQDVT 156
Query: 178 QAMMEWGKSVGK-TCITCKDTPGFV 249
+ ++ ++GK T + K+ G V
Sbjct: 157 ARVKDFYDALGKQTIVLNKEMTGHV 181
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 550,527,647
Number of Sequences: 1657284
Number of extensions: 11289154
Number of successful extensions: 29565
Number of sequences better than 10.0: 280
Number of HSP's better than 10.0 without gapping: 28111
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29481
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 34156095254
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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