Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= mg--0949
(668 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 112 9e-25
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 112 9e-25
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 112 9e-25
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 112 9e-25
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 107 5e-23
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 107 5e-23
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 107 5e-23
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 107 5e-23
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 107 5e-23
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 105 1e-22
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 104 3e-22
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 104 3e-22
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 104 3e-22
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 100 4e-21
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 99 1e-20
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 99 1e-20
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 99 1e-20
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 99 1e-20
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 99 1e-20
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 75 3e-13
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 75 3e-13
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 74 5e-13
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 50 8e-06
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 112 bits (270), Expect = 9e-25
Identities = 46/85 (54%), Positives = 61/85 (71%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHWDLPQ+LQD+GGW
Sbjct: 974 YRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGW 1033
Query: 448 MNPLIVDWFEDYARVVFSLFGIELK 522
NP ++D F+ YA F FG +K
Sbjct: 1034 ENPALIDLFDSYADFCFQTFGDRVK 1058
Score = 109 bits (262), Expect = 9e-24
Identities = 49/91 (53%), Positives = 58/91 (63%)
Frame = +1
Query: 250 GAGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSL 429
G Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T+FHWDLPQ+L
Sbjct: 445 GLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQAL 504
Query: 430 QDLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
QD GGW N +VD F DYA FS FG +K
Sbjct: 505 QDHGGWQNESVVDAFLDYAAFCFSTFGDRVK 535
Score = 105 bits (253), Expect = 1e-22
Identities = 47/89 (52%), Positives = 62/89 (69%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWDLPQ+LQD
Sbjct: 1443 GVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQD 1502
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
+GGW N IV F++YA V+F G ++K
Sbjct: 1503 VGGWENETIVQRFKEYADVLFQRLGDKVK 1531
Score = 74.1 bits (174), Expect = 4e-13
Identities = 30/68 (44%), Positives = 40/68 (58%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 233 DIEMATEL 256
D+ M L
Sbjct: 962 DLNMLRAL 969
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/61 (52%), Positives = 38/61 (62%)
Frame = +2
Query: 56 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 235
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 236 I 238
+
Sbjct: 1436 L 1436
Score = 47.2 bits (107), Expect = 5e-05
Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 220
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 221 LWERDIEM 244
D+ +
Sbjct: 435 KVASDVAL 442
Score = 44.0 bits (99), Expect = 5e-04
Identities = 25/81 (30%), Positives = 35/81 (43%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 448 MNPLIVDWFEDYARVVFSLFG 510
D F DYA F FG
Sbjct: 143 RTEAFADLFADYATFAFHSFG 163
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 112 bits (270), Expect = 9e-25
Identities = 46/85 (54%), Positives = 61/85 (71%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHWDLPQ+LQD+GGW
Sbjct: 974 YRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGW 1033
Query: 448 MNPLIVDWFEDYARVVFSLFGIELK 522
NP ++D F+ YA F FG +K
Sbjct: 1034 ENPALIDLFDSYADFCFQTFGDRVK 1058
Score = 109 bits (262), Expect = 9e-24
Identities = 49/91 (53%), Positives = 58/91 (63%)
Frame = +1
Query: 250 GAGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSL 429
G Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T+FHWDLPQ+L
Sbjct: 445 GLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQAL 504
Query: 430 QDLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
QD GGW N +VD F DYA FS FG +K
Sbjct: 505 QDHGGWQNESVVDAFLDYAAFCFSTFGDRVK 535
Score = 105 bits (253), Expect = 1e-22
Identities = 47/89 (52%), Positives = 62/89 (69%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWDLPQ+LQD
Sbjct: 1443 GVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQD 1502
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
+GGW N IV F++YA V+F G ++K
Sbjct: 1503 VGGWENETIVQRFKEYADVLFQRLGDKVK 1531
Score = 74.1 bits (174), Expect = 4e-13
Identities = 30/68 (44%), Positives = 40/68 (58%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 233 DIEMATEL 256
D+ M L
Sbjct: 962 DLNMLRAL 969
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/61 (52%), Positives = 38/61 (62%)
Frame = +2
Query: 56 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 235
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 236 I 238
+
Sbjct: 1436 L 1436
Score = 47.2 bits (107), Expect = 5e-05
Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 220
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 221 LWERDIEM 244
D+ +
Sbjct: 435 KVASDVAL 442
Score = 44.0 bits (99), Expect = 5e-04
Identities = 25/81 (30%), Positives = 35/81 (43%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 448 MNPLIVDWFEDYARVVFSLFG 510
D F DYA F FG
Sbjct: 143 RTEAFADLFADYATFAFHSFG 163
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 112 bits (270), Expect = 9e-25
Identities = 46/85 (54%), Positives = 61/85 (71%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHWDLPQ+LQD+GGW
Sbjct: 406 YRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGW 465
Query: 448 MNPLIVDWFEDYARVVFSLFGIELK 522
NP ++D F+ YA F FG +K
Sbjct: 466 ENPALIDLFDSYADFCFQTFGDRVK 490
Score = 105 bits (253), Expect = 1e-22
Identities = 47/89 (52%), Positives = 62/89 (69%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWDLPQ+LQD
Sbjct: 875 GVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQD 934
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
+GGW N IV F++YA V+F G ++K
Sbjct: 935 VGGWENETIVQRFKEYADVLFQRLGDKVK 963
Score = 74.1 bits (174), Expect = 4e-13
Identities = 30/68 (44%), Positives = 40/68 (58%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 334 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 393
Query: 233 DIEMATEL 256
D+ M L
Sbjct: 394 DLNMLRAL 401
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/61 (52%), Positives = 38/61 (62%)
Frame = +2
Query: 56 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 235
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 867
Query: 236 I 238
+
Sbjct: 868 L 868
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 112 bits (270), Expect = 9e-25
Identities = 46/85 (54%), Positives = 61/85 (71%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHWDLPQ+LQD+GGW
Sbjct: 974 YRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGW 1033
Query: 448 MNPLIVDWFEDYARVVFSLFGIELK 522
NP ++D F+ YA F FG +K
Sbjct: 1034 ENPALIDLFDSYADFCFQTFGDRVK 1058
Score = 109 bits (262), Expect = 9e-24
Identities = 49/91 (53%), Positives = 58/91 (63%)
Frame = +1
Query: 250 GAGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSL 429
G Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T+FHWDLPQ+L
Sbjct: 445 GLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQAL 504
Query: 430 QDLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
QD GGW N +VD F DYA FS FG +K
Sbjct: 505 QDHGGWQNESVVDAFLDYAAFCFSTFGDRVK 535
Score = 105 bits (253), Expect = 1e-22
Identities = 47/89 (52%), Positives = 62/89 (69%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWDLPQ+LQD
Sbjct: 1443 GVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQD 1502
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
+GGW N IV F++YA V+F G ++K
Sbjct: 1503 VGGWENETIVQRFKEYADVLFQRLGDKVK 1531
Score = 74.1 bits (174), Expect = 4e-13
Identities = 30/68 (44%), Positives = 40/68 (58%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 233 DIEMATEL 256
D+ M L
Sbjct: 962 DLNMLRAL 969
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/61 (52%), Positives = 38/61 (62%)
Frame = +2
Query: 56 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 235
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 236 I 238
+
Sbjct: 1436 L 1436
Score = 47.2 bits (107), Expect = 5e-05
Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 220
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 221 LWERDIEM 244
D+ +
Sbjct: 435 KVASDVAL 442
Score = 44.0 bits (99), Expect = 5e-04
Identities = 25/81 (30%), Positives = 35/81 (43%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 447
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 448 MNPLIVDWFEDYARVVFSLFG 510
D F DYA F FG
Sbjct: 143 RTEAFADLFADYATFAFHSFG 163
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 107 bits (256), Expect = 5e-23
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
GL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H+DLPQ+L+D
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED 129
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW++ I++ F+ YA+ FS FG +K
Sbjct: 130 QGGWLSEAIIESFDKYAQFCFSTFGDRVK 158
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 107 bits (256), Expect = 5e-23
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
GL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H+DLPQ+L+D
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED 129
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW++ I++ F+ YA+ FS FG +K
Sbjct: 130 QGGWLSEAIIESFDKYAQFCFSTFGDRVK 158
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 107 bits (256), Expect = 5e-23
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
GL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H+DLPQ+L+D
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED 129
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW++ I++ F+ YA+ FS FG +K
Sbjct: 130 QGGWLSEAIIESFDKYAQFCFSTFGDRVK 158
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 107 bits (256), Expect = 5e-23
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
GL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H+DLPQ+L+D
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED 129
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW++ I++ F+ YA+ FS FG +K
Sbjct: 130 QGGWLSEAIIESFDKYAQFCFSTFGDRVK 158
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 107 bits (256), Expect = 5e-23
Identities = 45/89 (50%), Positives = 64/89 (71%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
GL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H+DLPQ+L+D
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED 129
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW++ I++ F+ YA+ FS FG +K
Sbjct: 130 QGGWLSEAIIESFDKYAQFCFSTFGDRVK 158
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 105 bits (253), Expect = 1e-22
Identities = 45/89 (50%), Positives = 63/89 (70%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
GL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H+DLPQ+L+D
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLED 129
Query: 436 LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW + I++ F+ YA+ FS FG +K
Sbjct: 130 QGGWWSEAIIESFDKYAQFCFSTFGDRVK 158
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 104 bits (249), Expect = 3e-22
Identities = 44/90 (48%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HWDLP +LQ+
Sbjct: 145 GVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQE 204
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N I+D F DYA F +FG +K
Sbjct: 205 KYGGWKNDTIIDIFNDYATYCFQMFGDRVK 234
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
YRF+L W ++PTG + ++ +YY ++ L GI +VT++ H LP+ L
Sbjct: 597 YRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLL 656
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFG 510
GW+NP + F+ YA + F G
Sbjct: 657 HADGWLNPSTAEAFQAYAGLCFQELG 682
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/72 (38%), Positives = 41/72 (56%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 233 DIEMATELVYIS 268
D+ A + + +S
Sbjct: 137 DLS-ALDFIGVS 147
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 104 bits (249), Expect = 3e-22
Identities = 44/90 (48%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HWDLP +LQ+
Sbjct: 145 GVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQE 204
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N I+D F DYA F +FG +K
Sbjct: 205 KYGGWKNDTIIDIFNDYATYCFQMFGDRVK 234
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
YRF+L W ++PTG + ++ +YY ++ L GI +VT++ H LP+ L
Sbjct: 597 YRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLL 656
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFG 510
GW+NP + F+ YA + F G
Sbjct: 657 HADGWLNPSTAEAFQAYAGLCFQELG 682
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/72 (38%), Positives = 41/72 (56%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 233 DIEMATELVYIS 268
D+ A + + +S
Sbjct: 137 DLS-ALDFIGVS 147
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 104 bits (249), Expect = 3e-22
Identities = 44/90 (48%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HWDLP +LQ+
Sbjct: 145 GVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQE 204
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N I+D F DYA F +FG +K
Sbjct: 205 KYGGWKNDTIIDIFNDYATYCFQMFGDRVK 234
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
YRF+L W ++PTG + ++ +YY ++ L GI +VT++ H LP+ L
Sbjct: 597 YRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLL 656
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFG 510
GW+NP + F+ YA + F G
Sbjct: 657 HADGWLNPSTAEAFQAYAGLCFQELG 682
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/72 (38%), Positives = 41/72 (56%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 233 DIEMATELVYIS 268
D+ A + + +S
Sbjct: 137 DLS-ALDFIGVS 147
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 100 bits (240), Expect = 4e-21
Identities = 44/90 (48%), Positives = 63/90 (70%), Gaps = 2/90 (2%)
Frame = +1
Query: 259 LHFYRFSLSWPRLMPTGF-SNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQ- 432
++ YRFSLSWPRL+PTG + ++++ G ++Y++LID LL I P+VT+ HWDLPQ LQ
Sbjct: 105 VNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHWDLPQLLQV 164
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N + ++F DYA + F FG +K
Sbjct: 165 KYGGWQNVSMANYFRDYANLCFEAFGDRVK 194
Score = 67.7 bits (158), Expect = 4e-11
Identities = 29/68 (42%), Positives = 39/68 (57%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 232
TFP GF +G S++YQ EGAW+ KG SIWD H+ ++ DV CD Y+ +
Sbjct: 36 TFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQE 95
Query: 233 DIEMATEL 256
DI + EL
Sbjct: 96 DIILLREL 103
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 99.1 bits (236), Expect = 1e-20
Identities = 41/90 (45%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + + +G +YY L++ L + G++P+VT++HWDLPQ LQD
Sbjct: 143 GVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQD 202
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N + D F DYA + F FG ++K
Sbjct: 203 AYGGWANRALADHFRDYAELCFRHFGGQVK 232
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVH-------TKPEAIMDL-------- 187
TFP GF + SA+YQ EG W KG SIWD H A + L
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 188 TNGDVTCDSYHLWERDIEMATEL 256
GDV DSY+ RD E EL
Sbjct: 120 ATGDVASDSYNNVFRDTEALREL 142
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 99.1 bits (236), Expect = 1e-20
Identities = 41/90 (45%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + + +G +YY L++ L + G++P+VT++HWDLPQ LQD
Sbjct: 143 GVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQD 202
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N + D F DYA + F FG ++K
Sbjct: 203 AYGGWANRALADHFRDYAELCFRHFGGQVK 232
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
+RFSL W ++P G ++++ +YY + L+ I P+V ++ + LP+ L
Sbjct: 593 FRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLA 652
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
G W NP F +YAR+ F G +K
Sbjct: 653 RQGAWENPYTALAFAEYARLCFQELGHHVK 682
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVH-------TKPEAIMDL-------- 187
TFP GF + SA+YQ EG W KG SIWD H A + L
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 188 TNGDVTCDSYHLWERDIEMATEL 256
GDV DSY+ RD E EL
Sbjct: 120 ATGDVASDSYNNVFRDTEALREL 142
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 99.1 bits (236), Expect = 1e-20
Identities = 41/90 (45%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + + +G +YY L++ L + G++P+VT++HWDLPQ LQD
Sbjct: 143 GVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQD 202
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N + D F DYA + F FG ++K
Sbjct: 203 AYGGWANRALADHFRDYAELCFRHFGGQVK 232
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVH-------TKPEAIMDL-------- 187
TFP GF + SA+YQ EG W KG SIWD H A + L
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 188 TNGDVTCDSYHLWERDIEMATEL 256
GDV DSY+ RD E EL
Sbjct: 120 ATGDVASDSYNNVFRDTEALREL 142
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 99.1 bits (236), Expect = 1e-20
Identities = 41/90 (45%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + + +G +YY L++ L + G++P+VT++HWDLPQ LQD
Sbjct: 143 GVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQD 202
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N + D F DYA + F FG ++K
Sbjct: 203 AYGGWANRALADHFRDYAELCFRHFGGQVK 232
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
+RFSL W ++P G ++++ +YY + L+ I P+V ++ + LP+ L
Sbjct: 593 FRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLA 652
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
G W NP F +YAR+ F G +K
Sbjct: 653 RQGAWENPYTALAFAEYARLCFQELGHHVK 682
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVH-------TKPEAIMDL-------- 187
TFP GF + SA+YQ EG W KG SIWD H A + L
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 188 TNGDVTCDSYHLWERDIEMATEL 256
GDV DSY+ RD E EL
Sbjct: 120 ATGDVASDSYNNVFRDTEALREL 142
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 99.1 bits (236), Expect = 1e-20
Identities = 41/90 (45%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQD 435
G+ YRFS+SW R++P G + + +G +YY L++ L + G++P+VT++HWDLPQ LQD
Sbjct: 143 GVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQD 202
Query: 436 -LGGWMNPLIVDWFEDYARVVFSLFGIELK 522
GGW N + D F DYA + F FG ++K
Sbjct: 203 AYGGWANRALADHFRDYAELCFRHFGGQVK 232
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
+RFSL W ++P G ++++ +YY + L+ I P+V ++ + LP+ L
Sbjct: 593 FRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLA 652
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
G W NP F +YAR+ F G +K
Sbjct: 653 RQGAWENPYTALAFAEYARLCFQELGHHVK 682
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 15/83 (18%)
Frame = +2
Query: 53 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVH-------TKPEAIMDL-------- 187
TFP GF + SA+YQ EG W KG SIWD H A + L
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 188 TNGDVTCDSYHLWERDIEMATEL 256
GDV DSY+ RD E EL
Sbjct: 120 ATGDVASDSYNNVFRDTEALREL 142
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
Score = 33.5 bits (73), Expect = 0.70
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISE 330
GL YRFSLSW RL+P G + I++
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 74.5 bits (175), Expect = 3e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
Score = 33.5 bits (73), Expect = 0.70
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISE 330
GL YRFSLSW RL+P G + I++
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 73.7 bits (173), Expect = 5e-13
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +2
Query: 50 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 229
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 230 RDIEMATEL 256
D++ +L
Sbjct: 61 EDLKCIKQL 69
Score = 33.5 bits (73), Expect = 0.70
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +1
Query: 256 GLHFYRFSLSWPRLMPTGFSNKISE 330
GL YRFSLSW RL+P G + I++
Sbjct: 70 GLTHYRFSLSWSRLLPDGTTGFINQ 94
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 50.0 bits (114), Expect = 8e-06
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Frame = +1
Query: 268 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIF-----HWDLPQSLQ 432
+RFSL W ++P G ++++ +YY + L+ I P+V ++ + LP+ L
Sbjct: 320 FRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLA 379
Query: 433 DLGGWMNPLIVDWFEDYARVVFSLFGIELK 522
G W NP F +YAR+ F G +K
Sbjct: 380 RQGAWENPYTALAFAEYARLCFQELGHHVK 409
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,564,457
Number of Sequences: 237096
Number of extensions: 2518154
Number of successful extensions: 12603
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 12407
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12580
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7591280850
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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