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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= mg--0657
         (693 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

L48690-1|AAB59581.1|  390|Homo sapiens pyruvate dehydrogenase E1...   156   8e-38
X52710-1|CAA36934.1|  390|Homo sapiens protein ( Human mRNA for ...   102   1e-21
X52709-1|CAA36933.1|  390|Homo sapiens protein ( Human mRNA for ...   102   1e-21
M27257-1|AAA60051.1|  390|Homo sapiens pyruvate dehydrogenase E1...   102   1e-21
M24848-1|AAA36533.1|  390|Homo sapiens protein ( Human pyruvate ...   102   1e-21
L13318-1|AAA60227.1|  390|Homo sapiens pyruvate dehydrogenase E1...   102   1e-21
J03575-1|AAA60050.1|  390|Homo sapiens pyruvate dehydrogenase al...   102   1e-21
J03503-1|AAA60055.1|  414|Homo sapiens PDHA1 protein.                 102   1e-21
EF590117-1|ABQ59099.1|  428|Homo sapiens mitochondrial PDHA1 pro...   102   1e-21
D90084-1|BAA14121.1|  390|Homo sapiens pyruvate dehydrogenase al...   102   1e-21
BC002406-1|AAH02406.1|  390|Homo sapiens pyruvate dehydrogenase ...   102   1e-21
AL732326-7|CAI41291.1|  390|Homo sapiens pyruvate dehydrogenase ...   102   1e-21
AL732326-5|CAI41289.1|  180|Homo sapiens pyruvate dehydrogenase ...   102   1e-21
AL732326-4|CAI41288.1|  205|Homo sapiens pyruvate dehydrogenase ...   102   1e-21
AK222988-1|BAD96708.1|  390|Homo sapiens pyruvate dehydrogenase ...   102   1e-21
AK222740-1|BAD96460.1|  390|Homo sapiens pyruvate dehydrogenase ...   102   1e-21
EF576990-1|ABQ58815.1|  261|Homo sapiens PDHA1 protein.               101   2e-21
AM746210-1|CAN88919.1|  302|Homo sapiens PDHA1/LOC79064 protein ...   101   2e-21
AF125088-1|AAD23876.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125087-1|AAD23875.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125086-1|AAD23874.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125085-1|AAD23873.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125084-1|AAD23872.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125083-1|AAD23871.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125082-1|AAD23870.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125081-1|AAD23869.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125080-1|AAD23868.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125079-1|AAD23867.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125078-1|AAD23866.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125076-1|AAD23864.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125075-1|AAD23863.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125074-1|AAD23862.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125073-1|AAD23861.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125072-1|AAD23860.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125071-1|AAD23859.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125070-1|AAD23858.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125069-1|AAD23857.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125068-1|AAD23856.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125067-1|AAD23855.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125066-1|AAD23854.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125065-1|AAD23853.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125064-1|AAD23852.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125063-1|AAD23851.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125062-1|AAD23850.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125061-1|AAD23849.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125060-1|AAD23848.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125059-1|AAD23847.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125058-1|AAD23846.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125057-1|AAD23845.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125056-1|AAD23844.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125055-1|AAD23843.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125054-1|AAD23842.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
AF125053-1|AAD23841.1|  135|Homo sapiens pyruvate dehydrogenase ...   101   2e-21
M86808-1|AAA60232.1|  388|Homo sapiens pyruvate dehydrogenase co...    98   2e-20
BC127638-1|AAI27639.1|  388|Homo sapiens pyruvate dehydrogenase ...    98   2e-20
BC127637-1|AAI27638.1|  388|Homo sapiens pyruvate dehydrogenase ...    98   2e-20
BC119657-1|AAI19658.1|  388|Homo sapiens pyruvate dehydrogenase ...    98   2e-20
BC119656-1|AAI19657.1|  388|Homo sapiens pyruvate dehydrogenase ...    98   2e-20
BC094760-1|AAH94760.1|  407|Homo sapiens PDHA2 protein protein.        98   2e-20
BC030697-1|AAH30697.3|  388|Homo sapiens pyruvate dehydrogenase ...    98   2e-20
AL732326-6|CAI41290.1|  204|Homo sapiens pyruvate dehydrogenase ...    98   2e-20
BC066953-1|AAH66953.2|  388|Homo sapiens pyruvate dehydrogenase ...    97   5e-20
AL732326-3|CAI41287.1|  121|Homo sapiens pyruvate dehydrogenase ...    64   5e-10
Z14093-1|CAA78475.1|  445|Homo sapiens branched chain decarboxyl...    36   0.14 
S62652-1|AAB20222.2|  443|Homo sapiens branched-chain alpha-keto...    36   0.14 
S38327-1|AAB19268.2|  387|Homo sapiens protein ( branched-chain ...    36   0.14 
M22221-1|AAA35590.1|  378|Homo sapiens protein ( Human branched-...    36   0.14 
J04474-1|AAB59549.1|  444|Homo sapiens branched-chain alpha-keto...    36   0.14 
BC023983-1|AAH23983.1|  445|Homo sapiens branched chain keto aci...    36   0.14 
BC008933-1|AAH08933.1|  445|Homo sapiens branched chain keto aci...    36   0.14 
BC007878-1|AAH07878.1|  445|Homo sapiens branched chain keto aci...    36   0.14 
AK127598-1|BAC87051.1|  479|Homo sapiens  1.2.4.4).  protein.          36   0.14 
AL611964-2|CAH73872.1|  495|Homo sapiens REST corepressor 3 prot...    35   0.24 
AL590101-2|CAH72433.1|  495|Homo sapiens REST corepressor 3 prot...    35   0.24 
AK001738-1|BAA91872.1|  495|Homo sapiens protein ( Homo sapiens ...    35   0.24 
AB037764-1|BAA92581.1|  520|Homo sapiens KIAA1343 protein protein.     35   0.24 
AB209828-1|BAD93065.1|  444|Homo sapiens branched chain keto aci...    34   0.55 
AB058686-1|BAB47412.1| 1560|Homo sapiens KIAA1783 protein protein.     33   0.73 
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot...    33   1.3  
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ...    33   1.3  
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ...    33   1.3  
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.     33   1.3  
AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marke...    30   6.8  
AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein.             30   9.0  

>L48690-1|AAB59581.1|  390|Homo sapiens pyruvate dehydrogenase
           E1-alpha subunit precursor protein.
          Length = 390

 Score =  156 bits (378), Expect = 8e-38
 Identities = 90/235 (38%), Positives = 119/235 (50%), Gaps = 4/235 (1%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGLVCWGC---SRS*RGAGPVAPGAREVPCICTDATS 351
           +  A       I++    G T L+    +     S+S +    V    +E  C C   TS
Sbjct: 104 LERA--STPQTISSQPT-GLTALLSPGAFPSEKFSQSLQDEKEVVLKGKEDRCTCMPRTS 160

Query: 352 MVATGLLVRRSRWELEWPSPTS-TAPTGSHXXXXXXXXXQPGSTLRSLQHV*TRDLPCVF 528
             A     RR  W                            G    +        LPC+F
Sbjct: 161 TGAMASWERRCPWAAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIF 220

Query: 529 VCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           +CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 221 ICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 26/52 (50%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +2

Query: 356 WQRDC-WCAGPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           W+R C W AG       L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 167 WERRCPWAAG-----IALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>X52710-1|CAA36934.1|  390|Homo sapiens protein ( Human mRNA for
           liver pyruvate dehydrogenase (EC 1.2.4.1) E1'  subunit. 
           ).
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>X52709-1|CAA36933.1|  390|Homo sapiens protein ( Human mRNA for
           brain pyruvate dehydrogenase (EC 1.2.4.1). ).
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>M27257-1|AAA60051.1|  390|Homo sapiens pyruvate dehydrogenase
           E1-alpha subunit protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>M24848-1|AAA36533.1|  390|Homo sapiens protein ( Human pyruvate
           dehydrogenase alpha subunit mRNA, complete cds. ).
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>L13318-1|AAA60227.1|  390|Homo sapiens pyruvate dehydrogenase
           E1-alpha subunit protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>J03575-1|AAA60050.1|  390|Homo sapiens pyruvate dehydrogenase alpha
           subunit protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>J03503-1|AAA60055.1|  414|Homo sapiens PDHA1 protein.
          Length = 414

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 68  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 127

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 128 LEAGINPTDHLITAYRAHGFTFTRGL 153



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 240 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 299



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 150 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 209

Query: 426 DGE 434
             E
Sbjct: 210 KDE 212



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 196 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 237


>EF590117-1|ABQ59099.1|  428|Homo sapiens mitochondrial PDHA1
           protein.
          Length = 428

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 82  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 141

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 142 LEAGINPTDHLITAYRAHGFTFTRGL 167



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 254 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 313



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 164 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 223

Query: 426 DGE 434
             E
Sbjct: 224 KDE 226



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 210 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 251


>D90084-1|BAA14121.1|  390|Homo sapiens pyruvate dehydrogenase alpha
           subunit protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>BC002406-1|AAH02406.1|  390|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>AL732326-7|CAI41291.1|  390|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>AL732326-5|CAI41289.1|  180|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 protein.
          Length = 180

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 32/46 (69%), Positives = 41/46 (89%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQV 383
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQV
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQV 171


>AL732326-4|CAI41288.1|  205|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 protein.
          Length = 205

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 82  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 141

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 142 LEAGINPTDHLITAYRAHGFTFTRGL 167



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 28/42 (66%), Positives = 37/42 (88%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIV 371
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIV
Sbjct: 164 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIV 205


>AK222988-1|BAD96708.1|  390|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 variant protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>AK222740-1|BAD96460.1|  390|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 variant protein.
          Length = 390

 Score =  102 bits (244), Expect = 1e-21
 Identities = 44/86 (51%), Positives = 58/86 (67%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 180
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG 103

Query: 181 MRAAMRDADSVITAYRCHGWTYLMGL 258
           + A +   D +ITAYR HG+T+  GL
Sbjct: 104 LEAGINPTDHLITAYRAHGFTFTRGL 129



 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 216 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 275



 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 126 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 185

Query: 426 DGE 434
             E
Sbjct: 186 KDE 188



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 172 PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 213


>EF576990-1|ABQ58815.1|  261|Homo sapiens PDHA1 protein.
          Length = 261

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 87  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 146



 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 41/59 (69%), Positives = 49/59 (83%)
 Frame = +3

Query: 258 SVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGE 434
           SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY    E
Sbjct: 1   SVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDE 59



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 43  PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 84


>AM746210-1|CAN88919.1|  302|Homo sapiens PDHA1/LOC79064 protein
           protein.
          Length = 302

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 128 LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 187



 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +2

Query: 383 PVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           P+G+   L  +   +  V   LYGDGAANQGQ+FEAYNM+ L
Sbjct: 84  PLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAAL 125


>AF125088-1|AAD23876.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125087-1|AAD23875.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAXYCRS 74


>AF125086-1|AAD23874.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125085-1|AAD23873.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125084-1|AAD23872.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125083-1|AAD23871.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125082-1|AAD23870.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125081-1|AAD23869.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125080-1|AAD23868.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125079-1|AAD23867.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125078-1|AAD23866.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125076-1|AAD23864.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125075-1|AAD23863.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125074-1|AAD23862.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125073-1|AAD23861.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125072-1|AAD23860.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125071-1|AAD23859.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125070-1|AAD23858.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125069-1|AAD23857.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125068-1|AAD23856.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125067-1|AAD23855.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125066-1|AAD23854.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125065-1|AAD23853.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125064-1|AAD23852.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125063-1|AAD23851.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125062-1|AAD23850.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125061-1|AAD23849.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125060-1|AAD23848.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125059-1|AAD23847.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125058-1|AAD23846.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125057-1|AAD23845.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125056-1|AAD23844.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125055-1|AAD23843.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125054-1|AAD23842.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>AF125053-1|AAD23841.1|  135|Homo sapiens pyruvate dehydrogenase E1
           alpha subunit protein.
          Length = 135

 Score =  101 bits (242), Expect = 2e-21
 Identities = 40/60 (66%), Positives = 51/60 (85%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPC+F+CENN YGMGTSV+R++AST+YY RGD++PG+ VDGMD+L  REA RFA  YC +
Sbjct: 15  LPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRS 74


>M86808-1|AAA60232.1|  388|Homo sapiens pyruvate dehydrogenase
           complex protein.
          Length = 388

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRGL 127



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>BC127638-1|AAI27639.1|  388|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 2 protein.
          Length = 388

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRGL 127



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>BC127637-1|AAI27638.1|  388|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 2 protein.
          Length = 388

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRGL 127



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>BC119657-1|AAI19658.1|  388|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 2 protein.
          Length = 388

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRGL 127



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>BC119656-1|AAI19657.1|  388|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 2 protein.
          Length = 388

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRGL 127



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>BC094760-1|AAH94760.1|  407|Homo sapiens PDHA2 protein protein.
          Length = 407

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 143 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 202

Query: 426 DGE 434
           + E
Sbjct: 203 NDE 205



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 233 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 292



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 63  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 122

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 123 AGINPSDHVITSYRAHGVCYTRGL 146



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 188 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 230


>BC030697-1|AAH30697.3|  388|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 2 protein.
          Length = 388

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 53/63 (84%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 40/84 (47%), Positives = 53/84 (63%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMGL 258
           A +  +D VIT+YR HG  Y  GL
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRGL 127



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>AL732326-6|CAI41290.1|  204|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 protein.
          Length = 204

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G+SV  +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY  
Sbjct: 133 TRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNG 192

Query: 426 DGE 434
             E
Sbjct: 193 KDE 195



 Score = 93.1 bits (221), Expect = 9e-19
 Identities = 44/93 (47%), Positives = 58/93 (62%), Gaps = 7/93 (7%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG------- 159
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  G       
Sbjct: 44  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLT 103

Query: 160 QEAVAVGMRAAMRDADSVITAYRCHGWTYLMGL 258
           QEA  VG+ A +   D +ITAYR HG+T+  GL
Sbjct: 104 QEACCVGLEAGINPTDHLITAYRAHGFTFTRGL 136


>BC066953-1|AAH66953.2|  388|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 2 protein.
          Length = 388

 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 42/63 (66%), Positives = 52/63 (82%)
 Frame = +3

Query: 246 SHGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRA 425
           + G SV  +L+ELTGRR GC++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ 
Sbjct: 124 TRGPSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKG 183

Query: 426 DGE 434
           + E
Sbjct: 184 NDE 186



 Score = 94.7 bits (225), Expect = 3e-19
 Identities = 38/60 (63%), Positives = 49/60 (81%)
 Frame = +1

Query: 514 LPCVFVCENNGYGMGTSVDRSSASTEYYTRGDYVPGVWVDGMDVLATREAARFAIEYCNA 693
           LPCVF+CENN YGMGTS +R++AS +YY RG+++PG+ VDGMDVL  REA +FA  YC +
Sbjct: 214 LPCVFICENNLYGMGTSTERAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRS 273



 Score = 89.0 bits (211), Expect = 1e-17
 Identities = 39/83 (46%), Positives = 52/83 (62%)
 Frame = +1

Query: 7   LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 186
           L++GP  +  LT  + LK Y  +  +RR+E  +  LYK+K IRGFCHL  GQEA  VG+ 
Sbjct: 44  LEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLE 103

Query: 187 AAMRDADSVITAYRCHGWTYLMG 255
           A +  +D VIT+YR HG  Y  G
Sbjct: 104 AGINPSDHVITSYRAHGVCYTRG 126



 Score = 43.6 bits (98), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKL 508
           GP+G+   L  +      +   LYGDGAANQGQ+ EA+NM+ L
Sbjct: 169 GPLGAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAAL 211


>AL732326-3|CAI41287.1|  121|Homo sapiens pyruvate dehydrogenase
           (lipoamide) alpha 1 protein.
          Length = 121

 Score = 64.1 bits (149), Expect = 5e-10
 Identities = 26/50 (52%), Positives = 35/50 (70%)
 Frame = +1

Query: 1   HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHL 150
           H+L++GP  +  LT ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL
Sbjct: 72  HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHL 121


>Z14093-1|CAA78475.1|  445|Homo sapiens branched chain decarboxylase
           alpha  subunit protein.
          Length = 445

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 255 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 314

Query: 667 RFAI 678
           R A+
Sbjct: 315 RRAV 318


>S62652-1|AAB20222.2|  443|Homo sapiens branched-chain alpha-keto
           acid dehydrogenase E1 alpha subunit protein.
          Length = 443

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 253 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 312

Query: 667 RFAI 678
           R A+
Sbjct: 313 RRAV 316


>S38327-1|AAB19268.2|  387|Homo sapiens protein ( branched-chain
           alpha-keto acid dehydrogenase complex E1 alpha subunit
           [human, Genomic, 195 nt, segment 8 of 8]. ).
          Length = 387

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 253 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 312

Query: 667 RFAI 678
           R A+
Sbjct: 313 RRAV 316


>M22221-1|AAA35590.1|  378|Homo sapiens protein ( Human
           branched-chain alpha-keto acid dehydrogenase E1-alpha
           subunit (BCKDH) mRNA, partial cds. ).
          Length = 378

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 188 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 247

Query: 667 RFAI 678
           R A+
Sbjct: 248 RRAV 251


>J04474-1|AAB59549.1|  444|Homo sapiens branched-chain alpha-keto
           acid dehydrogenase protein.
          Length = 444

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 254 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 313

Query: 667 RFAI 678
           R A+
Sbjct: 314 RRAV 317


>BC023983-1|AAH23983.1|  445|Homo sapiens branched chain keto acid
           dehydrogenase E1, alpha polypeptide protein.
          Length = 445

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 255 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 314

Query: 667 RFAI 678
           R A+
Sbjct: 315 RRAV 318


>BC008933-1|AAH08933.1|  445|Homo sapiens branched chain keto acid
           dehydrogenase E1, alpha polypeptide protein.
          Length = 445

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 255 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 314

Query: 667 RFAI 678
           R A+
Sbjct: 315 RRAV 318


>BC007878-1|AAH07878.1|  445|Homo sapiens branched chain keto acid
           dehydrogenase E1, alpha polypeptide protein.
          Length = 445

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 255 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 314

Query: 667 RFAI 678
           R A+
Sbjct: 315 RRAV 318


>AK127598-1|BAC87051.1|  479|Homo sapiens  1.2.4.4).  protein.
          Length = 479

 Score = 35.9 bits (79), Expect = 0.14
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRG-DY-VPGVWVDGMDVL----ATREAA 666
           T + P +F C NNGY + T             RG  Y +  + VDG DV     AT+EA 
Sbjct: 289 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEAR 348

Query: 667 RFAI 678
           R A+
Sbjct: 349 RRAV 352


>AL611964-2|CAH73872.1|  495|Homo sapiens REST corepressor 3
           protein.
          Length = 495

 Score = 35.1 bits (77), Expect = 0.24
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
 Frame = -3

Query: 466 GGSVSVQSERDSPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQ 302
           G S   + E  +P A      + PAP+ T  PT P+     PP  LRP     P L R+ 
Sbjct: 373 GKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 432

Query: 301 PVLR 290
           P L+
Sbjct: 433 PPLQ 436


>AL590101-2|CAH72433.1|  495|Homo sapiens REST corepressor 3
           protein.
          Length = 495

 Score = 35.1 bits (77), Expect = 0.24
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
 Frame = -3

Query: 466 GGSVSVQSERDSPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQ 302
           G S   + E  +P A      + PAP+ T  PT P+     PP  LRP     P L R+ 
Sbjct: 373 GKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 432

Query: 301 PVLR 290
           P L+
Sbjct: 433 PPLQ 436


>AK001738-1|BAA91872.1|  495|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10876 fis, clone NT2RP4001838, weakly similar to
           Homo sapiens CoREST protein mRNA. ).
          Length = 495

 Score = 35.1 bits (77), Expect = 0.24
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
 Frame = -3

Query: 466 GGSVSVQSERDSPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQ 302
           G S   + E  +P A      + PAP+ T  PT P+     PP  LRP     P L R+ 
Sbjct: 373 GKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 432

Query: 301 PVLR 290
           P L+
Sbjct: 433 PPLQ 436


>AB037764-1|BAA92581.1|  520|Homo sapiens KIAA1343 protein protein.
          Length = 520

 Score = 35.1 bits (77), Expect = 0.24
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
 Frame = -3

Query: 466 GGSVSVQSERDSPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQ 302
           G S   + E  +P A      + PAP+ T  PT P+     PP  LRP     P L R+ 
Sbjct: 398 GKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 457

Query: 301 PVLR 290
           P L+
Sbjct: 458 PPLQ 461


>AB209828-1|BAD93065.1|  444|Homo sapiens branched chain keto acid
           dehydrogenase E1, alpha polypeptide variant protein.
          Length = 444

 Score = 33.9 bits (74), Expect = 0.55
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 5/63 (7%)
 Frame = +1

Query: 505 TRDLPCVFVCENNGYGMGTSVDRSSASTEYYTRGDY-VPGVWVDGMDVL----ATREAAR 669
           T + P +F C NNGY + T                Y +  + VDG DV     AT+EA R
Sbjct: 255 TLECPIIFFCRNNGYAISTPTSEQYRGDGIARGPGYGIMSIRVDGNDVFAVYNATKEARR 314

Query: 670 FAI 678
            A+
Sbjct: 315 RAV 317


>AB058686-1|BAB47412.1| 1560|Homo sapiens KIAA1783 protein protein.
          Length = 1560

 Score = 33.5 bits (73), Expect = 0.73
 Identities = 19/50 (38%), Positives = 24/50 (48%)
 Frame = +2

Query: 380 GPVGSWSGLRPQVPRRRGVTFALYGDGAANQGQLFEAYNMSKLGTCLASS 529
           GP G W G   Q PR+R  T  L  D A   G    A  ++ LG C ++S
Sbjct: 54  GPAGEWPGATVQQPRQRAPTALLQPDAAGPGGGGVSA-GVAVLGACPSAS 102


>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B protein.
          Length = 1960

 Score = 32.7 bits (71), Expect = 1.3
 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 10/79 (12%)
 Frame = -3

Query: 499  HVVGFEELTLVGGSV-SVQSERDSPS------ARYLWAKATPAPNGTCAP---TIPLPP* 350
            H  G ++L   GG   + Q ER SP       A +   K   AP   C+P     P PP 
Sbjct: 992  HPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCPPG 1051

Query: 349  KLRPYKCMEPPLPREQPVL 293
               P  C E PL    P L
Sbjct: 1052 SFPPGSCKEAPLVPSSPFL 1070


>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 2582

 Score = 32.7 bits (71), Expect = 1.3
 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 10/79 (12%)
 Frame = -3

Query: 499  HVVGFEELTLVGGSV-SVQSERDSPS------ARYLWAKATPAPNGTCAP---TIPLPP* 350
            H  G ++L   GG   + Q ER SP       A +   K   AP   C+P     P PP 
Sbjct: 1616 HPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCPPG 1675

Query: 349  KLRPYKCMEPPLPREQPVL 293
               P  C E PL    P L
Sbjct: 1676 SFPPGSCKEAPLVPSSPFL 1694


>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
            calmodulin and titin-interacting RhoGEF protein.
          Length = 2582

 Score = 32.7 bits (71), Expect = 1.3
 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 10/79 (12%)
 Frame = -3

Query: 499  HVVGFEELTLVGGSV-SVQSERDSPS------ARYLWAKATPAPNGTCAP---TIPLPP* 350
            H  G ++L   GG   + Q ER SP       A +   K   AP   C+P     P PP 
Sbjct: 1616 HPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCPPG 1675

Query: 349  KLRPYKCMEPPLPREQPVL 293
               P  C E PL    P L
Sbjct: 1676 SFPPGSCKEAPLVPSSPFL 1694


>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
          Length = 2584

 Score = 32.7 bits (71), Expect = 1.3
 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 10/79 (12%)
 Frame = -3

Query: 499  HVVGFEELTLVGGSV-SVQSERDSPS------ARYLWAKATPAPNGTCAP---TIPLPP* 350
            H  G ++L   GG   + Q ER SP       A +   K   AP   C+P     P PP 
Sbjct: 1616 HPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCPPG 1675

Query: 349  KLRPYKCMEPPLPREQPVL 293
               P  C E PL    P L
Sbjct: 1676 SFPPGSCKEAPLVPSSPFL 1694


>AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marker 4
           protein.
          Length = 2063

 Score = 30.3 bits (65), Expect = 6.8
 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
 Frame = +3

Query: 162 RSRGSRYESSDARCRLSNHRVSLSRMDLSHGVSVL-GVLSELTGRRTGCSRGKGGSMHLY 338
           R  G   E S  R  LSN  ++   + L   +S L   LSEL  R+ G S G  GS  L 
Sbjct: 447 RDGGFEPEKSRQRKSLSNPDIASETLTL---LSFLRSDLSELRVRKPGGSSGDRGSNPLD 503

Query: 339 GRNFYGGNGIVGAQVPL 389
           GR+     G VG   P+
Sbjct: 504 GRDSPSAGGPVGQLEPI 520


>AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein.
          Length = 1609

 Score = 29.9 bits (64), Expect = 9.0
 Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
 Frame = +3

Query: 210 SNHRVSLSRMDL-SHGVSVLGVL----SELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVG 374
           S  R SLS  D+ S  +++L  L    SEL  R+ G S G  GS  L GR+     G VG
Sbjct: 2   SRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVG 61

Query: 375 AQVPL 389
              P+
Sbjct: 62  QLEPI 66


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,572,544
Number of Sequences: 237096
Number of extensions: 2197841
Number of successful extensions: 7135
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 6531
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7115
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7951235188
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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