Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= mg--0579
(653 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 71 3e-12
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 71 4e-12
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 71 4e-12
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 71 4e-12
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 71 4e-12
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 71 4e-12
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 71 4e-12
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 71 4e-12
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 71 4e-12
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 69 2e-11
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 69 2e-11
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 69 2e-11
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 52 2e-06
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 52 2e-06
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 52 2e-06
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 49 1e-05
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 49 1e-05
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 49 1e-05
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 48 3e-05
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 48 3e-05
AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein. 48 3e-05
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 47 7e-05
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 47 7e-05
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 47 7e-05
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 47 7e-05
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 43 0.001
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 34 0.51
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 34 0.51
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 34 0.51
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 34 0.51
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 34 0.51
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 34 0.51
BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated... 33 0.89
AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated... 33 0.89
AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated... 33 0.89
AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens ... 33 0.89
AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium... 33 0.89
AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium... 33 0.89
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 33 1.2
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 32 2.1
EF157730-1|ABO15447.1| 35|Homo sapiens type II cAMP-dependent ... 31 2.7
BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein. 31 2.7
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 31 3.6
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 31 3.6
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 31 3.6
BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein. 31 3.6
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 31 3.6
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 31 3.6
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 31 3.6
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 31 3.6
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 31 3.6
BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated... 30 6.3
AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2... 30 6.3
AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium... 30 6.3
BC021201-1|AAH21201.1| 331|Homo sapiens junctional sarcoplasmic... 30 8.3
AK056978-1|BAB71330.1| 331|Homo sapiens protein ( Homo sapiens ... 30 8.3
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 71.3 bits (167), Expect = 3e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGAKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 140 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 199
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 200 IMMRTGLIKHTEYMEFLKSVP 220
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 18 RKRGIIAPHPTFDAARSLTDLQ--YDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAV 191
R +GI A T+ RS DL+ + F K ERS + I++AI+ NDF++NL + ++ +
Sbjct: 60 RAQGISAEPQTY---RSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNL-ELSQIQEI 115
Query: 192 VGAMMTQDFEAGSLIIREGE 251
V M ++ S II+EG+
Sbjct: 116 VDCMYPVEYGKDSCIIKEGD 135
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 230 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 269
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 140 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 199
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 200 IMMRTGLIKHTEYMEFLKSVP 220
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 18 RKRGIIAPHPTFDAARSLTDLQ--YDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAV 191
R +GI A T+ RS DL+ + F K ERS + I++AI+ NDF++NL + ++ +
Sbjct: 60 RAQGISAEPQTY---RSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNL-ELSQIQEI 115
Query: 192 VGAMMTQDFEAGSLIIREGE 251
V M ++ S II+EG+
Sbjct: 116 VDCMYPVEYGKDSCIIKEGD 135
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 230 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 269
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 128 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 187
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 188 IMMRTGLIKHTEYMEFLKSVP 208
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 18 RKRGIIAPHPTFDAARSLTDLQ--YDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAV 191
R +GI A T+ RS DL+ + F K ERS + I++AI+ NDF++NL + ++ +
Sbjct: 48 RAQGISAEPQTY---RSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNL-ELSQIQEI 103
Query: 192 VGAMMTQDFEAGSLIIREGE 251
V M ++ S II+EG+
Sbjct: 104 VDCMYPVEYGKDSCIIKEGD 123
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 218 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 257
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 128 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 187
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 188 IMMRTGLIKHTEYMEFLKSVP 208
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 18 RKRGIIAPHPTFDAARSLTDLQ--YDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAV 191
R +GI A T+ RS DL+ + F K ERS + I++AI+ NDF++NL + ++ +
Sbjct: 48 RAQGISAEPQTY---RSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNL-ELSQIQEI 103
Query: 192 VGAMMTQDFEAGSLIIREGE 251
V M ++ S II+EG+
Sbjct: 104 VDCMYPVEYGKDSCIIKEGD 123
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 218 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 257
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 13 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 72
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 73 IMMRTGLIKHTEYMEFLKSVP 93
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 103 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 142
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 128 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 187
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 188 IMMRTGLIKHTEYMEFLKSVP 208
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 18 RKRGIIAPHPTFDAARSLTDLQ--YDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAV 191
R +GI A T+ RS DL+ + F K ERS + I++AI+ NDF++NL + ++ +
Sbjct: 48 RAQGISAEPQTY---RSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNL-ELSQIQEI 103
Query: 192 VGAMMTQDFEAGSLIIREGE 251
V M ++ S II+EG+
Sbjct: 104 VDCMYPVEYGKDSCIIKEGD 123
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 218 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 257
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 13 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 72
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 73 IMMRTGLIKHTEYMEFLKSVP 93
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 103 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 142
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 155 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 215 IMMRTGLIKHTEYMEFLKSVP 235
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +3
Query: 15 RRKRGIIAPHPTFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAVV 194
R KR I+ PT + L+ + + K +S + I++AI+ NDF++NL + ++ +V
Sbjct: 73 RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNL-ELSQIQEIV 131
Query: 195 GAMMTQDFEAGSLIIREGE 251
M ++ S II+EG+
Sbjct: 132 DCMYPVEYGKDSCIIKEGD 150
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 245 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 284
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 70.9 bits (166), Expect = 4e-12
Identities = 31/81 (38%), Positives = 50/81 (61%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
++V G+ E K G + GPG+VFGELAILY R A+++ + ++W ++R+ FQ
Sbjct: 128 VYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 187
Query: 443 IMVRSERQEQEDNIRFLSSVP 505
IM+R+ + + + FL SVP
Sbjct: 188 IMMRTGLIKHTEYMEFLKSVP 208
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 18 RKRGIIAPHPTFDAARSLTDLQ--YDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLNAV 191
R +GI A T+ RS DL+ + F K ERS + I++AI+ NDF++NL + ++ +
Sbjct: 48 RAQGISAEPQTY---RSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNL-ELSQIQEI 103
Query: 192 VGAMMTQDFEAGSLIIREGE 251
V M ++ S II+EG+
Sbjct: 104 VDCMYPVEYGKDSCIIKEGD 123
Score = 39.5 bits (88), Expect = 0.010
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 532 LAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L++++D L+ + G ++RQG RGD F+II G V VT
Sbjct: 218 LSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVT 257
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 68.5 bits (160), Expect = 2e-11
Identities = 34/84 (40%), Positives = 47/84 (55%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
+FV A G+ E + +++ + FGELAILY R AS++ IT + W L+R VFQ
Sbjct: 205 IFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQN 264
Query: 443 IMVRSERQEQEDNIRFLSSVPLCK 514
IM R+ + E FL SV L K
Sbjct: 265 IMRRTAQARDEQYRNFLRSVSLLK 288
Score = 38.3 bits (85), Expect = 0.024
Identities = 16/48 (33%), Positives = 30/48 (62%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L+ + +L +I D L+ E++ G ++R+G+ G F+I+ G+V VT
Sbjct: 287 LKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 334
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +3
Query: 117 EQIRKAIMMNDFLRNLMDDERLNAVVGAMMTQDFEAGSLIIREGE 251
EQ R + L+NL +D +L ++ + + ++ G IIREGE
Sbjct: 275 EQYRNFLRSVSLLKNLPED-KLTKIIDCLEVEYYDKGDYIIREGE 318
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 68.5 bits (160), Expect = 2e-11
Identities = 34/84 (40%), Positives = 47/84 (55%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
+FV A G+ E + +++ + FGELAILY R AS++ IT + W L+R VFQ
Sbjct: 205 IFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQN 264
Query: 443 IMVRSERQEQEDNIRFLSSVPLCK 514
IM R+ + E FL SV L K
Sbjct: 265 IMRRTAQARDEQYRNFLRSVSLLK 288
Score = 38.3 bits (85), Expect = 0.024
Identities = 16/48 (33%), Positives = 30/48 (62%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L+ + +L +I D L+ E++ G ++R+G+ G F+I+ G+V VT
Sbjct: 287 LKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 334
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +3
Query: 117 EQIRKAIMMNDFLRNLMDDERLNAVVGAMMTQDFEAGSLIIREGE 251
EQ R + L+NL +D +L ++ + + ++ G IIREGE
Sbjct: 275 EQYRNFLRSVSLLKNLPED-KLTKIIDCLEVEYYDKGDYIIREGE 318
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 68.5 bits (160), Expect = 2e-11
Identities = 34/84 (40%), Positives = 47/84 (55%)
Frame = +2
Query: 263 LFVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQK 442
+FV A G+ E + +++ + FGELAILY R AS++ IT + W L+R VFQ
Sbjct: 205 IFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQN 264
Query: 443 IMVRSERQEQEDNIRFLSSVPLCK 514
IM R+ + E FL SV L K
Sbjct: 265 IMRRTAQARDEQYRNFLRSVSLLK 288
Score = 38.3 bits (85), Expect = 0.024
Identities = 16/48 (33%), Positives = 30/48 (62%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L+ + +L +I D L+ E++ G ++R+G+ G F+I+ G+V VT
Sbjct: 287 LKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 334
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +3
Query: 117 EQIRKAIMMNDFLRNLMDDERLNAVVGAMMTQDFEAGSLIIREGE 251
EQ R + L+NL +D +L ++ + + ++ G IIREGE
Sbjct: 275 EQYRNFLRSVSLLKNLPED-KLTKIIDCLEVEYYDKGDYIIREGE 318
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 51.6 bits (118), Expect = 2e-06
Identities = 23/81 (28%), Positives = 48/81 (59%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + +G+ V N G FGELA++Y R A+++ T+ ++W ++R +++I
Sbjct: 174 YVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRI 233
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 234 LMGSTLRKRKMYEEFLSKVSI 254
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD FYII G V
Sbjct: 255 LESLEKWERLTVADRLEPVQFEDGEKIVVQGEPGDDFYIITEGTASV 301
Score = 31.9 bits (69), Expect = 2.1
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Frame = +1
Query: 523 HIELAQISDFLKREFFST---GTAVVRQGDRGDKFYIIRGGEVVV 648
H++ + SD F T G V++QG+ GD FY++ GEV V
Sbjct: 139 HLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDV 183
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 51.6 bits (118), Expect = 2e-06
Identities = 23/81 (28%), Positives = 48/81 (59%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + +G+ V N G FGELA++Y R A+++ T+ ++W ++R +++I
Sbjct: 175 YVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRI 234
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 235 LMGSTLRKRKMYEEFLSKVSI 255
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD FYII G V
Sbjct: 256 LESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASV 302
Score = 31.9 bits (69), Expect = 2.1
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Frame = +1
Query: 523 HIELAQISDFLKREFFST---GTAVVRQGDRGDKFYIIRGGEVVV 648
H++ + SD F T G V++QG+ GD FY++ GEV V
Sbjct: 140 HLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDV 184
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 51.6 bits (118), Expect = 2e-06
Identities = 23/81 (28%), Positives = 48/81 (59%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + +G+ V N G FGELA++Y R A+++ T+ ++W ++R +++I
Sbjct: 175 YVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRI 234
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 235 LMGSTLRKRKMYEEFLSKVSI 255
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/47 (36%), Positives = 24/47 (51%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD FYII G V
Sbjct: 256 LESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASV 302
Score = 31.9 bits (69), Expect = 2.1
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Frame = +1
Query: 523 HIELAQISDFLKREFFST---GTAVVRQGDRGDKFYIIRGGEVVV 648
H++ + SD F T G V++QG+ GD FY++ GEV V
Sbjct: 140 HLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDV 184
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 49.2 bits (112), Expect = 1e-05
Identities = 22/62 (35%), Positives = 39/62 (62%)
Frame = +2
Query: 341 FGELAILYKAKRFASIRCITEARVWTLERRVFQKIMVRSERQEQEDNIRFLSSVPLCKKY 520
FGELA++Y R A+I +E +W L+R F++I+V++ ++++ F+ SVPL K
Sbjct: 206 FGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSL 265
Query: 521 TI 526
+
Sbjct: 266 EV 267
Score = 37.1 bits (82), Expect = 0.055
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E +I D + + + G ++ QG++ D FYII GEV +
Sbjct: 262 LKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSI 308
Score = 31.9 bits (69), Expect = 2.1
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGG--EVVVT 651
+L+Q+ D + V+ QGD GD FY+I G +++VT
Sbjct: 147 QLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVT 189
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 49.2 bits (112), Expect = 1e-05
Identities = 22/62 (35%), Positives = 39/62 (62%)
Frame = +2
Query: 341 FGELAILYKAKRFASIRCITEARVWTLERRVFQKIMVRSERQEQEDNIRFLSSVPLCKKY 520
FGELA++Y R A+I +E +W L+R F++I+V++ ++++ F+ SVPL K
Sbjct: 206 FGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSL 265
Query: 521 TI 526
+
Sbjct: 266 EV 267
Score = 31.9 bits (69), Expect = 2.1
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGG--EVVVT 651
+L+Q+ D + V+ QGD GD FY+I G +++VT
Sbjct: 147 QLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVT 189
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 49.2 bits (112), Expect = 1e-05
Identities = 22/62 (35%), Positives = 39/62 (62%)
Frame = +2
Query: 341 FGELAILYKAKRFASIRCITEARVWTLERRVFQKIMVRSERQEQEDNIRFLSSVPLCKKY 520
FGELA++Y R A+I +E +W L+R F++I+V++ ++++ F+ SVPL K
Sbjct: 206 FGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSL 265
Query: 521 TI 526
+
Sbjct: 266 EV 267
Score = 31.9 bits (69), Expect = 2.1
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGG--EVVVT 651
+L+Q+ D + V+ QGD GD FY+I G +++VT
Sbjct: 147 QLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVT 189
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 48.0 bits (109), Expect = 3e-05
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = +2
Query: 305 GQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIMVRSERQEQEDNI 484
G+ V N+ FGELA++Y R A+I + +W L+R F++I+V++ ++++
Sbjct: 209 GRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYE 268
Query: 485 RFLSSVPLCK 514
F+ S+P K
Sbjct: 269 SFIESLPFLK 278
Score = 37.5 bits (83), Expect = 0.041
Identities = 14/48 (29%), Positives = 27/48 (56%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L+ + E ++ D + + ++ G ++ QGD D F+I+ GEV +T
Sbjct: 277 LKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKIT 324
Score = 32.3 bits (70), Expect = 1.6
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGG 636
+++Q+ D + + G V+ QGD GD FY+I G
Sbjct: 162 QMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRG 197
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 48.0 bits (109), Expect = 3e-05
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = +2
Query: 305 GQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIMVRSERQEQEDNI 484
G+ V N+ FGELA++Y R A+I + +W L+R F++I+V++ ++++
Sbjct: 209 GRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYE 268
Query: 485 RFLSSVPLCK 514
F+ S+P K
Sbjct: 269 SFIESLPFLK 278
Score = 37.5 bits (83), Expect = 0.041
Identities = 14/48 (29%), Positives = 27/48 (56%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVVT 651
L+ + E ++ D + + ++ G ++ QGD D F+I+ GEV +T
Sbjct: 277 LKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKIT 324
Score = 32.3 bits (70), Expect = 1.6
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGG 636
+++Q+ D + + G V+ QGD GD FY+I G
Sbjct: 162 QMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRG 197
>AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein.
Length = 306
Score = 48.0 bits (109), Expect = 3e-05
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = +2
Query: 305 GQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIMVRSERQEQEDNI 484
G+ V N+ FGELA++Y R A+I + +W L+R F++I+V++ ++++
Sbjct: 209 GRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYE 268
Query: 485 RFLSSVPLCK 514
F+ S+P K
Sbjct: 269 SFIESLPFLK 278
Score = 32.3 bits (70), Expect = 1.6
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGG 636
+++Q+ D + + G V+ QGD GD FY+I G
Sbjct: 162 QMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRG 197
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 46.8 bits (106), Expect = 7e-05
Identities = 21/81 (25%), Positives = 46/81 (56%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + + + + G G FGELA++Y R A+++ T ++W ++R +++I
Sbjct: 175 YVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRI 234
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 235 LMGSTLRKRKMYEEFLSKVSI 255
Score = 35.5 bits (78), Expect = 0.17
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
E + I D + F G V++QGD GD FY+I GE V
Sbjct: 145 ERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDV 184
Score = 35.1 bits (77), Expect = 0.22
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 9 KQRRKRGIIAPHP-TFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLN 185
K RR+RG I+ T + A S V KD ++ + KAI N +L D+ER +
Sbjct: 92 KGRRRRGAISAEVYTEEDAASYVR---KVIPKDYKTMAALAKAIEKNVLFSHLDDNER-S 147
Query: 186 AVVGAMMTQDFEAGSLIIREGE 251
+ AM + F AG +I++G+
Sbjct: 148 DIFDAMFSVSFIAGETVIQQGD 169
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/47 (34%), Positives = 25/47 (53%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD+F+II G V
Sbjct: 256 LESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAV 302
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 46.8 bits (106), Expect = 7e-05
Identities = 21/81 (25%), Positives = 46/81 (56%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + + + + G G FGELA++Y R A+++ T ++W ++R +++I
Sbjct: 175 YVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRI 234
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 235 LMGSTLRKRKMYEEFLSKVSI 255
Score = 35.5 bits (78), Expect = 0.17
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
E + I D + F G V++QGD GD FY+I GE V
Sbjct: 145 ERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDV 184
Score = 35.1 bits (77), Expect = 0.22
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 9 KQRRKRGIIAPHP-TFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLN 185
K RR+RG I+ T + A S V KD ++ + KAI N +L D+ER +
Sbjct: 92 KGRRRRGAISAEVYTEEDAASYVR---KVIPKDYKTMAALAKAIEKNVLFSHLDDNER-S 147
Query: 186 AVVGAMMTQDFEAGSLIIREGE 251
+ AM + F AG +I++G+
Sbjct: 148 DIFDAMFSVSFIAGETVIQQGD 169
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/47 (34%), Positives = 25/47 (53%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD+F+II G V
Sbjct: 256 LESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAV 302
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 46.8 bits (106), Expect = 7e-05
Identities = 21/81 (25%), Positives = 46/81 (56%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + + + + G G FGELA++Y R A+++ T ++W ++R +++I
Sbjct: 175 YVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRI 234
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 235 LMGSTLRKRKMYEEFLSKVSI 255
Score = 35.5 bits (78), Expect = 0.17
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
E + I D + F G V++QGD GD FY+I GE V
Sbjct: 145 ERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDV 184
Score = 35.1 bits (77), Expect = 0.22
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 9 KQRRKRGIIAPHP-TFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLN 185
K RR+RG I+ T + A S V KD ++ + KAI N +L D+ER +
Sbjct: 92 KGRRRRGAISAEVYTEEDAASYVR---KVIPKDYKTMAALAKAIEKNVLFSHLDDNER-S 147
Query: 186 AVVGAMMTQDFEAGSLIIREGE 251
+ AM + F AG +I++G+
Sbjct: 148 DIFDAMFSVSFIAGETVIQQGD 169
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/47 (34%), Positives = 25/47 (53%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD+F+II G V
Sbjct: 256 LESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAV 302
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 46.8 bits (106), Expect = 7e-05
Identities = 21/81 (25%), Positives = 46/81 (56%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + + + + G G FGELA++Y R A+++ T ++W ++R +++I
Sbjct: 175 YVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRI 234
Query: 446 MVRSERQEQEDNIRFLSSVPL 508
++ S ++++ FLS V +
Sbjct: 235 LMGSTLRKRKMYEEFLSKVSI 255
Score = 35.5 bits (78), Expect = 0.17
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
E + I D + F G V++QGD GD FY+I GE V
Sbjct: 145 ERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDV 184
Score = 35.1 bits (77), Expect = 0.22
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 9 KQRRKRGIIAPHP-TFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLN 185
K RR+RG I+ T + A S V KD ++ + KAI N +L D+ER +
Sbjct: 92 KGRRRRGAISAEVYTEEDAASYVR---KVIPKDYKTMAALAKAIEKNVLFSHLDDNER-S 147
Query: 186 AVVGAMMTQDFEAGSLIIREGE 251
+ AM + F AG +I++G+
Sbjct: 148 DIFDAMFSVSFIAGETVIQQGD 169
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/47 (34%), Positives = 25/47 (53%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + E ++D L+ F G +V QG+ GD+F+II G V
Sbjct: 256 LESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAV 302
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 42.7 bits (96), Expect = 0.001
Identities = 17/68 (25%), Positives = 38/68 (55%)
Frame = +2
Query: 266 FVSASGQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
+V G+ + + + + G G FGELA++Y R A+++ T ++W ++R +++I
Sbjct: 175 YVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRI 234
Query: 446 MVRSERQE 469
++ + E
Sbjct: 235 LMEDPKWE 242
Score = 35.5 bits (78), Expect = 0.17
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
E + I D + F G V++QGD GD FY+I GE V
Sbjct: 145 ERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDV 184
Score = 35.1 bits (77), Expect = 0.22
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 9 KQRRKRGIIAPHP-TFDAARSLTDLQYDVFEKDERSAEQIRKAIMMNDFLRNLMDDERLN 185
K RR+RG I+ T + A S V KD ++ + KAI N +L D+ER +
Sbjct: 92 KGRRRRGAISAEVYTEEDAASYVR---KVIPKDYKTMAALAKAIEKNVLFSHLDDNER-S 147
Query: 186 AVVGAMMTQDFEAGSLIIREGE 251
+ AM + F AG +I++G+
Sbjct: 148 DIFDAMFSVSFIAGETVIQQGD 169
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 33.9 bits (74), Expect = 0.51
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F +++
Sbjct: 638 GVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 693
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 33.9 bits (74), Expect = 0.51
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F +++
Sbjct: 587 GVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 642
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 33.9 bits (74), Expect = 0.51
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F +++
Sbjct: 638 GVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 693
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 33.9 bits (74), Expect = 0.51
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F +++
Sbjct: 587 GVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 642
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 33.9 bits (74), Expect = 0.51
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F +++
Sbjct: 587 GVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 642
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 33.9 bits (74), Expect = 0.51
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F +++
Sbjct: 441 GVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 496
>BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 33.1 bits (72), Expect = 0.89
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ + +K A+ A++R +T + ++R QK+
Sbjct: 596 SGSLEVIQDDEVVAILGKGDVFGD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKV 653
Query: 446 M 448
+
Sbjct: 654 L 654
>AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 33.1 bits (72), Expect = 0.89
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ + +K A+ A++R +T + ++R QK+
Sbjct: 596 SGSLEVIQDDEVVAILGKGDVFGD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKV 653
Query: 446 M 448
+
Sbjct: 654 L 654
>AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 989
Score = 33.1 bits (72), Expect = 0.89
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ + +K A+ A++R +T + ++R QK+
Sbjct: 623 SGSLEVIQDDEVVAILGKGDVFGD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKV 680
Query: 446 M 448
+
Sbjct: 681 L 681
>AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens
potassium channel h-eag. ).
Length = 962
Score = 33.1 bits (72), Expect = 0.89
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ + +K A+ A++R +T + ++R QK+
Sbjct: 596 SGSLEVIQDDEVVAILGKGDVFGD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKV 653
Query: 446 M 448
+
Sbjct: 654 L 654
>AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium
channel eagB protein.
Length = 989
Score = 33.1 bits (72), Expect = 0.89
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ + +K A+ A++R +T + ++R QK+
Sbjct: 623 SGSLEVIQDDEVVAILGKGDVFGD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKV 680
Query: 446 M 448
+
Sbjct: 681 L 681
>AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium
channel eag protein.
Length = 962
Score = 33.1 bits (72), Expect = 0.89
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ + +K A+ A++R +T + ++R QK+
Sbjct: 596 SGSLEVIQDDEVVAILGKGDVFGD--VFWKEATLAQSCANVRALTYCDLHVIKRDALQKV 653
Query: 446 M 448
+
Sbjct: 654 L 654
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 32.7 bits (71), Expect = 1.2
Identities = 14/39 (35%), Positives = 24/39 (61%)
Frame = +2
Query: 332 GEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G FGE+ +L K +R AS+R T R+++L F +++
Sbjct: 414 GSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVL 452
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 332 GEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKI 445
G FGE+ +L K +R AS+R T R+++L F ++
Sbjct: 535 GSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEV 572
>EF157730-1|ABO15447.1| 35|Homo sapiens type II cAMP-dependent
regulatory protein kinase beta protein.
Length = 35
Score = 31.5 bits (68), Expect = 2.7
Identities = 12/33 (36%), Positives = 20/33 (60%)
Frame = +1
Query: 529 ELAQISDFLKREFFSTGTAVVRQGDRGDKFYII 627
+++Q+ D + + G V+ QGD GD FY+I
Sbjct: 2 QMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVI 34
>BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein.
Length = 474
Score = 31.5 bits (68), Expect = 2.7
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +1
Query: 553 LKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + +S G V R+GD G + YIIR G++ V
Sbjct: 382 LQPQTYSPGEYVCRKGDIGQEMYIIREGQLAV 413
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 31.1 bits (67), Expect = 3.6
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +1
Query: 553 LKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + FS G + R+GD G + YII+ G++ V
Sbjct: 179 LRPQVFSPGDYICRKGDIGKEMYIIKEGKLAV 210
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 31.1 bits (67), Expect = 3.6
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +1
Query: 553 LKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + FS G + R+GD G + YII+ G++ V
Sbjct: 470 LRPQVFSPGDYICRKGDIGKEMYIIKEGKLAV 501
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 31.1 bits (67), Expect = 3.6
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +1
Query: 553 LKREFFSTGTAVVRQGDRGDKFYIIRGGEVVV 648
L+ + FS G + R+GD G + YII+ G++ V
Sbjct: 470 LRPQVFSPGDYICRKGDIGKEMYIIKEGKLAV 501
>BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein.
Length = 80
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +1
Query: 508 LQEIHHIELAQISDFLKREFFSTGTAVVRQGDRGDKFYII 627
L+ + E ++D L+ F G +V QG+ GD FYII
Sbjct: 21 LESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYII 60
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 31.1 bits (67), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F ++
Sbjct: 147 GLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVL 202
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 31.1 bits (67), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F ++
Sbjct: 268 GLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVL 323
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 31.1 bits (67), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F ++
Sbjct: 471 GLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVL 526
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 31.1 bits (67), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F ++
Sbjct: 471 GLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVL 526
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 31.1 bits (67), Expect = 3.6
Identities = 16/56 (28%), Positives = 26/56 (46%)
Frame = +2
Query: 281 GQFEALKSGQVVKNFGPGEVFGELAILYKAKRFASIRCITEARVWTLERRVFQKIM 448
G L G G FGE+ +L + +R AS+R T R+++L F ++
Sbjct: 408 GLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVL 463
>BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 5 protein.
Length = 988
Score = 30.3 bits (65), Expect = 6.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ I +K A A++R +T + ++R K+
Sbjct: 592 SGSLEVIQDDEVVAILGKGDVFGD--IFWKETTLAHACANVRALTYCDLHIIKREALLKV 649
Query: 446 M 448
+
Sbjct: 650 L 650
>AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2
protein.
Length = 988
Score = 30.3 bits (65), Expect = 6.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ I +K A A++R +T + ++R K+
Sbjct: 592 SGSLEVIQDDEVVAILGKGDVFGD--IFWKETTLAHACANVRALTYCDLHIIKREALLKV 649
Query: 446 M 448
+
Sbjct: 650 L 650
>AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium
channel EAG2 protein.
Length = 988
Score = 30.3 bits (65), Expect = 6.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Frame = +2
Query: 278 SGQFEALKSGQVVKNFGPGEVFGELAILYK----AKRFASIRCITEARVWTLERRVFQKI 445
SG E ++ +VV G G+VFG+ I +K A A++R +T + ++R K+
Sbjct: 592 SGSLEVIQDDEVVAILGKGDVFGD--IFWKETTLAHACANVRALTYCDLHIIKREALLKV 649
Query: 446 M 448
+
Sbjct: 650 L 650
>BC021201-1|AAH21201.1| 331|Homo sapiens junctional sarcoplasmic
reticulum protein 1 protein.
Length = 331
Score = 29.9 bits (64), Expect = 8.3
Identities = 14/44 (31%), Positives = 23/44 (52%)
Frame = +1
Query: 349 TGNLI*SQTIRFNTMYNRGEGVDIREKSLSKNHGSK*TPGTGRQ 480
T L S ++ ++ G VD R K + K ++ TPGTG++
Sbjct: 38 TPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKE 81
>AK056978-1|BAB71330.1| 331|Homo sapiens protein ( Homo sapiens
cDNA FLJ32416 fis, clone SKMUS2000774, weakly similar to
BALBIANI RING PROTEIN 1. ).
Length = 331
Score = 29.9 bits (64), Expect = 8.3
Identities = 14/44 (31%), Positives = 23/44 (52%)
Frame = +1
Query: 349 TGNLI*SQTIRFNTMYNRGEGVDIREKSLSKNHGSK*TPGTGRQ 480
T L S ++ ++ G VD R K + K ++ TPGTG++
Sbjct: 38 TPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKE 81
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,131,323
Number of Sequences: 237096
Number of extensions: 1937376
Number of successful extensions: 3451
Number of sequences better than 10.0: 64
Number of HSP's better than 10.0 without gapping: 3270
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3451
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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