Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= mg--0523
(690 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 116 6e-26
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 116 6e-26
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 116 6e-26
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 116 6e-26
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 114 2e-25
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 114 2e-25
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 114 2e-25
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 114 2e-25
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 114 2e-25
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 113 4e-25
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 100 4e-21
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 100 4e-21
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 100 4e-21
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 100 4e-21
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 100 4e-21
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 97 4e-20
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 93 6e-19
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 93 6e-19
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 93 6e-19
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 63 8e-10
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 60 6e-09
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 60 6e-09
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 54 4e-07
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 116 bits (280), Expect = 6e-26
Identities = 45/88 (51%), Positives = 66/88 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ +++ L + YRFS+SWSRI P+G + IN G+DYYN LIN ++A+NI P +T++HW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD+GGW NP ++D F++ FC
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFC 1049
Score = 107 bits (256), Expect = 5e-23
Identities = 45/82 (54%), Positives = 62/82 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ ++ LG++ YRFS+SWSRILP G IN+AG++YY LI+ +LA +I+P +TIYHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 445 DLPQSFQDLGGWANPMIVDWFE 510
DLPQ+ QD+GGW N IV F+
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFK 1516
Score = 91.5 bits (217), Expect = 3e-18
Identities = 39/88 (44%), Positives = 53/88 (60%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
DV ++ L Y+FS+SWSRI P G + + G+ YYN LI+ + I+P T++HW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD GGW N +VD F FC
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYAAFC 526
Score = 74.1 bits (174), Expect = 4e-13
Identities = 31/55 (56%), Positives = 39/55 (70%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
F D F +G S+++YQ+EGAWD DGK SIWD H S +KD +TGD+A DSYH
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYH 957
Score = 68.5 bits (160), Expect = 2e-11
Identities = 29/55 (52%), Positives = 41/55 (74%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F + A++A+YQ+EGAW DGK LSIWD +H +P +++ + GDVA DSYH
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYH 1430
Score = 52.8 bits (121), Expect = 1e-06
Identities = 24/55 (43%), Positives = 37/55 (67%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F +GAST ++ VEG W E G+ +SIWD ++ + + +T +VA+DSYH
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYH 434
Score = 41.5 bits (93), Expect = 0.003
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
+YA VLF+ GD+VKFWI++NEP
Sbjct: 1517 EYADVLFQRLGDKVKFWITLNEP 1539
Score = 39.9 bits (89), Expect = 0.008
Identities = 19/40 (47%), Positives = 22/40 (55%)
Frame = +3
Query: 459 LPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
L GG P L YA F+ FGDRVKFW++ NEP
Sbjct: 1027 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEP 1066
Score = 37.9 bits (84), Expect = 0.034
Identities = 13/56 (23%), Positives = 30/56 (53%)
Frame = +1
Query: 292 LNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHWDLPQS 459
+ Y+ +SW+++LP+G ++ + Y L+ + ++P + ++H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS 139
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA F FGDRVK W++ +EP
Sbjct: 521 DYAAFCFSTFGDRVKLWVTFHEP 543
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 116 bits (280), Expect = 6e-26
Identities = 45/88 (51%), Positives = 66/88 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ +++ L + YRFS+SWSRI P+G + IN G+DYYN LIN ++A+NI P +T++HW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD+GGW NP ++D F++ FC
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFC 1049
Score = 107 bits (256), Expect = 5e-23
Identities = 45/82 (54%), Positives = 62/82 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ ++ LG++ YRFS+SWSRILP G IN+AG++YY LI+ +LA +I+P +TIYHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 445 DLPQSFQDLGGWANPMIVDWFE 510
DLPQ+ QD+GGW N IV F+
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFK 1516
Score = 91.5 bits (217), Expect = 3e-18
Identities = 39/88 (44%), Positives = 53/88 (60%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
DV ++ L Y+FS+SWSRI P G + + G+ YYN LI+ + I+P T++HW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD GGW N +VD F FC
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYAAFC 526
Score = 74.1 bits (174), Expect = 4e-13
Identities = 31/55 (56%), Positives = 39/55 (70%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
F D F +G S+++YQ+EGAWD DGK SIWD H S +KD +TGD+A DSYH
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYH 957
Score = 68.5 bits (160), Expect = 2e-11
Identities = 29/55 (52%), Positives = 41/55 (74%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F + A++A+YQ+EGAW DGK LSIWD +H +P +++ + GDVA DSYH
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYH 1430
Score = 52.8 bits (121), Expect = 1e-06
Identities = 24/55 (43%), Positives = 37/55 (67%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F +GAST ++ VEG W E G+ +SIWD ++ + + +T +VA+DSYH
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYH 434
Score = 41.5 bits (93), Expect = 0.003
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
+YA VLF+ GD+VKFWI++NEP
Sbjct: 1517 EYADVLFQRLGDKVKFWITLNEP 1539
Score = 39.9 bits (89), Expect = 0.008
Identities = 19/40 (47%), Positives = 22/40 (55%)
Frame = +3
Query: 459 LPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
L GG P L YA F+ FGDRVKFW++ NEP
Sbjct: 1027 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEP 1066
Score = 37.9 bits (84), Expect = 0.034
Identities = 13/56 (23%), Positives = 30/56 (53%)
Frame = +1
Query: 292 LNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHWDLPQS 459
+ Y+ +SW+++LP+G ++ + Y L+ + ++P + ++H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS 139
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA F FGDRVK W++ +EP
Sbjct: 521 DYAAFCFSTFGDRVKLWVTFHEP 543
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 116 bits (280), Expect = 6e-26
Identities = 45/88 (51%), Positives = 66/88 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ +++ L + YRFS+SWSRI P+G + IN G+DYYN LIN ++A+NI P +T++HW
Sbjct: 394 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 453
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD+GGW NP ++D F++ FC
Sbjct: 454 DLPQALQDIGGWENPALIDLFDSYADFC 481
Score = 107 bits (256), Expect = 5e-23
Identities = 45/82 (54%), Positives = 62/82 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ ++ LG++ YRFS+SWSRILP G IN+AG++YY LI+ +LA +I+P +TIYHW
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926
Query: 445 DLPQSFQDLGGWANPMIVDWFE 510
DLPQ+ QD+GGW N IV F+
Sbjct: 927 DLPQTLQDVGGWENETIVQRFK 948
Score = 74.1 bits (174), Expect = 4e-13
Identities = 31/55 (56%), Positives = 39/55 (70%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
F D F +G S+++YQ+EGAWD DGK SIWD H S +KD +TGD+A DSYH
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYH 389
Score = 68.5 bits (160), Expect = 2e-11
Identities = 29/55 (52%), Positives = 41/55 (74%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F + A++A+YQ+EGAW DGK LSIWD +H +P +++ + GDVA DSYH
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYH 862
Score = 41.5 bits (93), Expect = 0.003
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
+YA VLF+ GD+VKFWI++NEP
Sbjct: 949 EYADVLFQRLGDKVKFWITLNEP 971
Score = 39.9 bits (89), Expect = 0.008
Identities = 19/40 (47%), Positives = 22/40 (55%)
Frame = +3
Query: 459 LPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
L GG P L YA F+ FGDRVKFW++ NEP
Sbjct: 459 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEP 498
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 116 bits (280), Expect = 6e-26
Identities = 45/88 (51%), Positives = 66/88 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ +++ L + YRFS+SWSRI P+G + IN G+DYYN LIN ++A+NI P +T++HW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD+GGW NP ++D F++ FC
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFC 1049
Score = 107 bits (256), Expect = 5e-23
Identities = 45/82 (54%), Positives = 62/82 (75%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
D+ ++ LG++ YRFS+SWSRILP G IN+AG++YY LI+ +LA +I+P +TIYHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 445 DLPQSFQDLGGWANPMIVDWFE 510
DLPQ+ QD+GGW N IV F+
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFK 1516
Score = 91.5 bits (217), Expect = 3e-18
Identities = 39/88 (44%), Positives = 53/88 (60%)
Frame = +1
Query: 265 DVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHW 444
DV ++ L Y+FS+SWSRI P G + + G+ YYN LI+ + I+P T++HW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498
Query: 445 DLPQSFQDLGGWANPMIVDWFETTLRFC 528
DLPQ+ QD GGW N +VD F FC
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYAAFC 526
Score = 74.1 bits (174), Expect = 4e-13
Identities = 31/55 (56%), Positives = 39/55 (70%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
F D F +G S+++YQ+EGAWD DGK SIWD H S +KD +TGD+A DSYH
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYH 957
Score = 68.5 bits (160), Expect = 2e-11
Identities = 29/55 (52%), Positives = 41/55 (74%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F + A++A+YQ+EGAW DGK LSIWD +H +P +++ + GDVA DSYH
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYH 1430
Score = 52.8 bits (121), Expect = 1e-06
Identities = 24/55 (43%), Positives = 37/55 (67%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP+ F +GAST ++ VEG W E G+ +SIWD ++ + + +T +VA+DSYH
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYH 434
Score = 41.5 bits (93), Expect = 0.003
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
+YA VLF+ GD+VKFWI++NEP
Sbjct: 1517 EYADVLFQRLGDKVKFWITLNEP 1539
Score = 39.9 bits (89), Expect = 0.008
Identities = 19/40 (47%), Positives = 22/40 (55%)
Frame = +3
Query: 459 LPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
L GG P L YA F+ FGDRVKFW++ NEP
Sbjct: 1027 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEP 1066
Score = 37.9 bits (84), Expect = 0.034
Identities = 13/56 (23%), Positives = 30/56 (53%)
Frame = +1
Query: 292 LNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYHWDLPQS 459
+ Y+ +SW+++LP+G ++ + Y L+ + ++P + ++H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS 139
Score = 36.3 bits (80), Expect = 0.10
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA F FGDRVK W++ +EP
Sbjct: 521 DYAAFCFSTFGDRVKLWVTFHEP 543
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 114 bits (275), Expect = 2e-25
Identities = 45/92 (48%), Positives = 68/92 (73%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLT 432
L++ D++ +K+LGL YRFS+SWSR+LP G INQ GIDYYN +I+++L N + P +T
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
Query: 433 IYHWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+YH+DLPQ+ +D GGW + I++ F+ +FC
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFC 149
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINE 575
YA+ F FGDRVK WI+INE
Sbjct: 145 YAQFCFSTFGDRVKQWITINE 165
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 114 bits (275), Expect = 2e-25
Identities = 45/92 (48%), Positives = 68/92 (73%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLT 432
L++ D++ +K+LGL YRFS+SWSR+LP G INQ GIDYYN +I+++L N + P +T
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
Query: 433 IYHWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+YH+DLPQ+ +D GGW + I++ F+ +FC
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFC 149
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINE 575
YA+ F FGDRVK WI+INE
Sbjct: 145 YAQFCFSTFGDRVKQWITINE 165
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 114 bits (275), Expect = 2e-25
Identities = 45/92 (48%), Positives = 68/92 (73%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLT 432
L++ D++ +K+LGL YRFS+SWSR+LP G INQ GIDYYN +I+++L N + P +T
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
Query: 433 IYHWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+YH+DLPQ+ +D GGW + I++ F+ +FC
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFC 149
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINE 575
YA+ F FGDRVK WI+INE
Sbjct: 145 YAQFCFSTFGDRVKQWITINE 165
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 114 bits (275), Expect = 2e-25
Identities = 45/92 (48%), Positives = 68/92 (73%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLT 432
L++ D++ +K+LGL YRFS+SWSR+LP G INQ GIDYYN +I+++L N + P +T
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
Query: 433 IYHWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+YH+DLPQ+ +D GGW + I++ F+ +FC
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFC 149
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINE 575
YA+ F FGDRVK WI+INE
Sbjct: 145 YAQFCFSTFGDRVKQWITINE 165
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 114 bits (275), Expect = 2e-25
Identities = 45/92 (48%), Positives = 68/92 (73%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLT 432
L++ D++ +K+LGL YRFS+SWSR+LP G INQ GIDYYN +I+++L N + P +T
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
Query: 433 IYHWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+YH+DLPQ+ +D GGW + I++ F+ +FC
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFC 149
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINE 575
YA+ F FGDRVK WI+INE
Sbjct: 145 YAQFCFSTFGDRVKQWITINE 165
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 113 bits (273), Expect = 4e-25
Identities = 45/92 (48%), Positives = 68/92 (73%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLT 432
L++ D++ +K+LGL YRFS+SWSR+LP G INQ GIDYYN +I+++L N + P +T
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVT 117
Query: 433 IYHWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+YH+DLPQ+ +D GGW + I++ F+ +FC
Sbjct: 118 LYHFDLPQTLEDQGGWWSEAIIESFDKYAQFC 149
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 34.7 bits (76), Expect = 0.31
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINE 575
YA+ F FGDRVK WI+INE
Sbjct: 145 YAQFCFSTFGDRVKQWITINE 165
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 100 bits (240), Expect = 4e-21
Identities = 42/92 (45%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Frame = +1
Query: 262 RDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYH 441
RD E ++ELG+ YRFS+SW+R+LP+G A N+ G+ YY L+ + ++P +T+YH
Sbjct: 134 RDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYH 193
Query: 442 WDLPQSFQD-LGGWANPMIVDWFETTLRFCSR 534
WDLPQ QD GGWAN + D F C R
Sbjct: 194 WDLPQRLQDAYGGWANRALADHFRDYAELCFR 225
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 16/71 (22%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHM----------------SPSPIKDG 220
FPD F + +A+YQ EG W + GK SIWD H +PSP++
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP- 119
Query: 221 STGDVAADSYH 253
+TGDVA+DSY+
Sbjct: 120 ATGDVASDSYN 130
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/23 (52%), Positives = 19/23 (82%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA++ F +FG +VK+WI+I+ P
Sbjct: 218 DYAELCFRHFGGQVKYWITIDNP 240
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 100 bits (240), Expect = 4e-21
Identities = 42/92 (45%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Frame = +1
Query: 262 RDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYH 441
RD E ++ELG+ YRFS+SW+R+LP+G A N+ G+ YY L+ + ++P +T+YH
Sbjct: 134 RDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYH 193
Query: 442 WDLPQSFQD-LGGWANPMIVDWFETTLRFCSR 534
WDLPQ QD GGWAN + D F C R
Sbjct: 194 WDLPQRLQDAYGGWANRALADHFRDYAELCFR 225
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Frame = +1
Query: 268 VEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY--- 438
+ +++E+ + +RFS+ W+ ILP G +Q+N + YY + +E++ NI P + ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 439 --HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+ LP+ G W NP F R C
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLC 673
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 16/71 (22%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHM----------------SPSPIKDG 220
FPD F + +A+YQ EG W + GK SIWD H +PSP++
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP- 119
Query: 221 STGDVAADSYH 253
+TGDVA+DSY+
Sbjct: 120 ATGDVASDSYN 130
Score = 37.9 bits (84), Expect = 0.034
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = +3
Query: 444 GFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
G L R G PY +YA++ F+ G VK WI++NEP
Sbjct: 646 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/23 (52%), Positives = 19/23 (82%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA++ F +FG +VK+WI+I+ P
Sbjct: 218 DYAELCFRHFGGQVKYWITIDNP 240
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 100 bits (240), Expect = 4e-21
Identities = 42/92 (45%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Frame = +1
Query: 262 RDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYH 441
RD E ++ELG+ YRFS+SW+R+LP+G A N+ G+ YY L+ + ++P +T+YH
Sbjct: 134 RDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYH 193
Query: 442 WDLPQSFQD-LGGWANPMIVDWFETTLRFCSR 534
WDLPQ QD GGWAN + D F C R
Sbjct: 194 WDLPQRLQDAYGGWANRALADHFRDYAELCFR 225
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 16/71 (22%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHM----------------SPSPIKDG 220
FPD F + +A+YQ EG W + GK SIWD H +PSP++
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP- 119
Query: 221 STGDVAADSYH 253
+TGDVA+DSY+
Sbjct: 120 ATGDVASDSYN 130
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/23 (52%), Positives = 19/23 (82%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA++ F +FG +VK+WI+I+ P
Sbjct: 218 DYAELCFRHFGGQVKYWITIDNP 240
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 100 bits (240), Expect = 4e-21
Identities = 42/92 (45%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Frame = +1
Query: 262 RDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYH 441
RD E ++ELG+ YRFS+SW+R+LP+G A N+ G+ YY L+ + ++P +T+YH
Sbjct: 134 RDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYH 193
Query: 442 WDLPQSFQD-LGGWANPMIVDWFETTLRFCSR 534
WDLPQ QD GGWAN + D F C R
Sbjct: 194 WDLPQRLQDAYGGWANRALADHFRDYAELCFR 225
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Frame = +1
Query: 268 VEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY--- 438
+ +++E+ + +RFS+ W+ ILP G +Q+N + YY + +E++ NI P + ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 439 --HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+ LP+ G W NP F R C
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLC 673
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 16/71 (22%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHM----------------SPSPIKDG 220
FPD F + +A+YQ EG W + GK SIWD H +PSP++
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP- 119
Query: 221 STGDVAADSYH 253
+TGDVA+DSY+
Sbjct: 120 ATGDVASDSYN 130
Score = 37.9 bits (84), Expect = 0.034
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = +3
Query: 444 GFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
G L R G PY +YA++ F+ G VK WI++NEP
Sbjct: 646 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/23 (52%), Positives = 19/23 (82%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA++ F +FG +VK+WI+I+ P
Sbjct: 218 DYAELCFRHFGGQVKYWITIDNP 240
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 100 bits (240), Expect = 4e-21
Identities = 42/92 (45%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Frame = +1
Query: 262 RDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIYH 441
RD E ++ELG+ YRFS+SW+R+LP+G A N+ G+ YY L+ + ++P +T+YH
Sbjct: 134 RDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYH 193
Query: 442 WDLPQSFQD-LGGWANPMIVDWFETTLRFCSR 534
WDLPQ QD GGWAN + D F C R
Sbjct: 194 WDLPQRLQDAYGGWANRALADHFRDYAELCFR 225
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Frame = +1
Query: 268 VEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY--- 438
+ +++E+ + +RFS+ W+ ILP G +Q+N + YY + +E++ NI P + ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 439 --HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+ LP+ G W NP F R C
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLC 673
Score = 50.0 bits (114), Expect = 8e-06
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 16/71 (22%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHM----------------SPSPIKDG 220
FPD F + +A+YQ EG W + GK SIWD H +PSP++
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP- 119
Query: 221 STGDVAADSYH 253
+TGDVA+DSY+
Sbjct: 120 ATGDVASDSYN 130
Score = 37.9 bits (84), Expect = 0.034
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = +3
Query: 444 GFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
G L R G PY +YA++ F+ G VK WI++NEP
Sbjct: 646 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/23 (52%), Positives = 19/23 (82%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEP 578
DYA++ F +FG +VK+WI+I+ P
Sbjct: 218 DYAELCFRHFGGQVKYWITIDNP 240
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 97.5 bits (232), Expect = 4e-20
Identities = 40/92 (43%), Positives = 65/92 (70%), Gaps = 2/92 (2%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGF-ANQINQAGIDYYNNLINEMLANNIKPFLTI 435
+ D+ +++EL +N YRFS+SW R+LP+G A Q+N+ GI++Y++LI+ +L++NI P +T+
Sbjct: 94 QEDIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTL 153
Query: 436 YHWDLPQSFQ-DLGGWANPMIVDWFETTLRFC 528
+HWDLPQ Q GGW N + ++F C
Sbjct: 154 HHWDLPQLLQVKYGGWQNVSMANYFRDYANLC 185
Score = 63.7 bits (148), Expect = 6e-10
Identities = 26/55 (47%), Positives = 33/55 (60%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSYH 253
FP F +G +++YQ EGAWD+DGK SIWDV H + T DVA D Y+
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYY 91
Score = 38.3 bits (85), Expect = 0.026
Identities = 14/24 (58%), Positives = 19/24 (79%)
Frame = +3
Query: 510 DYAKVLFENFGDRVKFWISINEPK 581
DYA + FE FGDRVK WI+ ++P+
Sbjct: 180 DYANLCFEAFGDRVKHWITFSDPR 203
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 93.5 bits (222), Expect = 6e-19
Identities = 35/91 (38%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY 438
++D+ + +G++FY+FS+SW R+ P G N G+ YY+ L++ ++ NI+P +T+Y
Sbjct: 135 EKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLY 194
Query: 439 HWDLPQSFQD-LGGWANPMIVDWFETTLRFC 528
HWDLP + Q+ GGW N I+D F +C
Sbjct: 195 HWDLPLALQEKYGGWKNDTIIDIFNDYATYC 225
Score = 60.1 bits (139), Expect = 7e-09
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY 438
K+ +E++ + + YRF++ W+ +LP+G + +N+ + YY +++E L I +T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 439 -----HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
H LP+ GW NP + F+ C
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLC 677
Score = 47.6 bits (108), Expect = 4e-05
Identities = 23/54 (42%), Positives = 34/54 (62%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F +G T + QVEG+W +DGK SIWD H + +K+ S+ + ++DSY
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSY 131
Score = 39.9 bits (89), Expect = 0.008
Identities = 21/49 (42%), Positives = 27/49 (55%)
Frame = +3
Query: 432 DLPLGFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
DLPL K +GG + DYA F+ FGDRVK+WI+I+ P
Sbjct: 197 DLPLALQEK---YGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 35.1 bits (77), Expect = 0.24
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINEPKQI 587
YA + F+ GD VK WI+INEP ++
Sbjct: 673 YAGLCFQELGDLVKLWITINEPNRL 697
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 93.5 bits (222), Expect = 6e-19
Identities = 35/91 (38%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY 438
++D+ + +G++FY+FS+SW R+ P G N G+ YY+ L++ ++ NI+P +T+Y
Sbjct: 135 EKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLY 194
Query: 439 HWDLPQSFQD-LGGWANPMIVDWFETTLRFC 528
HWDLP + Q+ GGW N I+D F +C
Sbjct: 195 HWDLPLALQEKYGGWKNDTIIDIFNDYATYC 225
Score = 60.1 bits (139), Expect = 7e-09
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY 438
K+ +E++ + + YRF++ W+ +LP+G + +N+ + YY +++E L I +T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 439 -----HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
H LP+ GW NP + F+ C
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLC 677
Score = 47.6 bits (108), Expect = 4e-05
Identities = 23/54 (42%), Positives = 34/54 (62%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F +G T + QVEG+W +DGK SIWD H + +K+ S+ + ++DSY
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSY 131
Score = 39.9 bits (89), Expect = 0.008
Identities = 21/49 (42%), Positives = 27/49 (55%)
Frame = +3
Query: 432 DLPLGFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
DLPL K +GG + DYA F+ FGDRVK+WI+I+ P
Sbjct: 197 DLPLALQEK---YGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 35.1 bits (77), Expect = 0.24
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINEPKQI 587
YA + F+ GD VK WI+INEP ++
Sbjct: 673 YAGLCFQELGDLVKLWITINEPNRL 697
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 93.5 bits (222), Expect = 6e-19
Identities = 35/91 (38%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY 438
++D+ + +G++FY+FS+SW R+ P G N G+ YY+ L++ ++ NI+P +T+Y
Sbjct: 135 EKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLY 194
Query: 439 HWDLPQSFQD-LGGWANPMIVDWFETTLRFC 528
HWDLP + Q+ GGW N I+D F +C
Sbjct: 195 HWDLPLALQEKYGGWKNDTIIDIFNDYATYC 225
Score = 60.1 bits (139), Expect = 7e-09
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Frame = +1
Query: 259 KRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY 438
K+ +E++ + + YRF++ W+ +LP+G + +N+ + YY +++E L I +T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 439 -----HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
H LP+ GW NP + F+ C
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLC 677
Score = 47.6 bits (108), Expect = 4e-05
Identities = 23/54 (42%), Positives = 34/54 (62%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F +G T + QVEG+W +DGK SIWD H + +K+ S+ + ++DSY
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSY 131
Score = 39.9 bits (89), Expect = 0.008
Identities = 21/49 (42%), Positives = 27/49 (55%)
Frame = +3
Query: 432 DLPLGFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
DLPL K +GG + DYA F+ FGDRVK+WI+I+ P
Sbjct: 197 DLPLALQEK---YGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 35.1 bits (77), Expect = 0.24
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +3
Query: 513 YAKVLFENFGDRVKFWISINEPKQI 587
YA + F+ GD VK WI+INEP ++
Sbjct: 673 YAGLCFQELGDLVKLWITINEPNRL 697
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 63.3 bits (147), Expect = 8e-10
Identities = 27/54 (50%), Positives = 32/54 (59%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK L +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 50.0 bits (114), Expect = 8e-06
Identities = 21/40 (52%), Positives = 29/40 (72%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGI 372
L++ D++ +K+LGL YRFS+SWSR+LP G INQ I
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 50.0 bits (114), Expect = 8e-06
Identities = 21/40 (52%), Positives = 29/40 (72%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGI 372
L++ D++ +K+LGL YRFS+SWSR+LP G INQ I
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 60.5 bits (140), Expect = 6e-09
Identities = 26/54 (48%), Positives = 31/54 (57%)
Frame = +2
Query: 89 FPDYFEFGASTASYQVEGAWDEDGKSLSIWDVAAHMSPSPIKDGSTGDVAADSY 250
FP F + A+TA+YQVEG WD DGK +WD H + TGDVA SY
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSY 56
Score = 50.0 bits (114), Expect = 8e-06
Identities = 21/40 (52%), Positives = 29/40 (72%)
Frame = +1
Query: 253 LYKRDVEIMKELGLNFYRFSVSWSRILPSGFANQINQAGI 372
L++ D++ +K+LGL YRFS+SWSR+LP G INQ I
Sbjct: 58 LWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 54.4 bits (125), Expect = 4e-07
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Frame = +1
Query: 268 VEIMKELGLNFYRFSVSWSRILPSGFANQINQAGIDYYNNLINEMLANNIKPFLTIY--- 438
+ +++E+ + +RFS+ W+ ILP G +Q+N + YY + +E++ NI P + ++
Sbjct: 309 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 368
Query: 439 --HWDLPQSFQDLGGWANPMIVDWFETTLRFC 528
+ LP+ G W NP F R C
Sbjct: 369 APNQGLPRLLARQGAWENPYTALAFAEYARLC 400
Score = 37.9 bits (84), Expect = 0.034
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = +3
Query: 444 GFAPKLPRFGGLGQPYDRRLV*DYAKVLFENFGDRVKFWISINEP 578
G L R G PY +YA++ F+ G VK WI++NEP
Sbjct: 373 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 417
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,019,604
Number of Sequences: 237096
Number of extensions: 2574673
Number of successful extensions: 4953
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 4674
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4937
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7895240574
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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