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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= mg--0516
         (703 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC031219-1|AAH31219.1|  366|Homo sapiens lipase, family member J...    50   1e-05
AL139406-3|CAH73713.1|  366|Homo sapiens lipase, family member J...    50   1e-05
EF426482-1|ABR08387.1|  399|Homo sapiens lipase K protein.             48   3e-05
AL358532-3|CAH71058.2|  399|Homo sapiens lipase, family member K...    48   3e-05
X05997-2|CAA29414.1|  392|Homo sapiens gastric lipase precursor ...    47   6e-05
X05997-1|CAA29413.1|  398|Homo sapiens gastric lipase precursor ...    47   6e-05
BC113711-1|AAI13712.1|  398|Homo sapiens lipase, gastric protein.      47   6e-05
BC112272-1|AAI12273.1|  398|Homo sapiens lipase, gastric protein.      47   6e-05
AY631869-1|AAT38115.1|  398|Homo sapiens lipase, gastric protein.      47   6e-05
AL358532-2|CAH71056.1|  365|Homo sapiens lipase, gastric protein.      47   6e-05
AL358532-1|CAH71057.1|  398|Homo sapiens lipase, gastric protein.      47   6e-05
AK223468-1|BAD97188.1|  398|Homo sapiens lipase, gastric variant...    47   6e-05
Z31690-1|CAA83495.1|  399|Homo sapiens lysosomal acid lipase pro...    46   1e-04
X76488-1|CAA54026.1|  399|Homo sapiens sterol esterase protein.        46   1e-04
U08464-1|AAB60328.1|  399|Homo sapiens lysosomal acid lipase pro...    46   1e-04
U04285-1|AAB60327.1|  399|Homo sapiens lysosomal acid lipase/cho...    46   1e-04
M74775-1|AAA59519.1|  399|Homo sapiens lysosomal acid lipase/cho...    46   1e-04
BC012287-1|AAH12287.1|  399|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL513533-3|CAI13517.1|  290|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL513533-2|CAI13516.1|  399|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL513533-1|CAI13515.1|  343|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL353751-4|CAI12237.1|  290|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL353751-3|CAI12236.1|  399|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL353751-1|CAI12234.1|  343|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AL353146-2|CAI12380.1|  343|Homo sapiens lipase A, lysosomal aci...    46   1e-04
AK222760-1|BAD96480.1|  399|Homo sapiens lipase A precursor vari...    46   1e-04
AK125193-1|BAC86078.1|  401|Homo sapiens .  protein.                   46   1e-04
EF426483-1|ABR08388.1|  398|Homo sapiens lipase N protein.             42   0.002
AL358532-5|CAH71060.2|  398|Homo sapiens lipase, family member N...    42   0.002
EF426484-1|ABR08389.1|  423|Homo sapiens lipase M protein.             41   0.004
AL358532-7|CAO77925.1|  423|Homo sapiens lipase, family member M...    41   0.004
AL353113-2|CAH72238.2|  423|Homo sapiens lipase, family member M...    41   0.004
AL353751-2|CAI12235.1|  219|Homo sapiens lipase A, lysosomal aci...    41   0.005
BC022443-1|AAH22443.1|  192|Homo sapiens ZCCHC10 protein protein.      31   3.0  
EF186229-1|ABM67095.1|  451|Homo sapiens lipase H protein.             31   4.0  
BC064941-1|AAH64941.1|  451|Homo sapiens lipase, member H protein.     31   4.0  
AY093498-1|AAM18803.1|  451|Homo sapiens lipase H protein.             31   4.0  
AY036912-1|AAK63178.1|  451|Homo sapiens membrane-bound phosphat...    31   4.0  
AK074229-1|BAB85023.1|  323|Homo sapiens protein ( Homo sapiens ...    31   4.0  

>BC031219-1|AAH31219.1|  366|Homo sapiens lipase, family member J
           protein.
          Length = 366

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 23/69 (33%), Positives = 36/69 (52%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G++ C   +F   +C N+LF   G      N + L V   H PAG +V+ + H+ QL+N+
Sbjct: 211 GSKLCPLQIF-DKICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNS 269

Query: 429 NFFRRYDHG 455
              + YD G
Sbjct: 270 THLKAYDWG 278



 Score = 35.1 bits (77), Expect = 0.24
 Identities = 23/103 (22%), Positives = 46/103 (44%)
 Frame = +1

Query: 4   KRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSI 183
           +  + Y+GHSQGTT+ +   S   +   +I    A APV   ++  + L+++     + +
Sbjct: 132 QEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSPLIRMTYKWKSIV 191

Query: 184 EALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
            A +   G  +   ++ F   VG     +  F + C  I + +
Sbjct: 192 MAFS---GNKDFLPKTSFKKFVGSKLCPLQIFDKICLNILFMM 231


>AL139406-3|CAH73713.1|  366|Homo sapiens lipase, family member J
           protein.
          Length = 366

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 23/69 (33%), Positives = 36/69 (52%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G++ C   +F   +C N+LF   G      N + L V   H PAG +V+ + H+ QL+N+
Sbjct: 211 GSKLCPLQIF-DKICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNS 269

Query: 429 NFFRRYDHG 455
              + YD G
Sbjct: 270 THLKAYDWG 278



 Score = 34.7 bits (76), Expect = 0.32
 Identities = 22/103 (21%), Positives = 46/103 (44%)
 Frame = +1

Query: 4   KRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSI 183
           +  + Y+GHSQGTT+ +   S   +   +I    A APV   ++  + L+++     + +
Sbjct: 132 QEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSPLIRMTYKWKSIV 191

Query: 184 EALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
            A +   G  +   ++ F   +G     +  F + C  I + +
Sbjct: 192 MAFS---GNKDFLPKTSFKKFIGSKLCPLQIFDKICLNILFMM 231


>EF426482-1|ABR08387.1|  399|Homo sapiens lipase K protein.
          Length = 399

 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 20/59 (33%), Positives = 33/59 (55%)
 Frame = +3

Query: 279 FQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           F+ +C+N LF  +G      N + L V L H PAG +V+ + H+ Q +N+   + +D G
Sbjct: 251 FRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWG 309



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 22/53 (41%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G++RL+Y+GHSQGTT+ +   S  PE   KI    A APV  +++  + + KL
Sbjct: 162 GQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKL 214



 Score = 31.1 bits (67), Expect = 4.0
 Identities = 16/50 (32%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           DI AD +DV  L  ++   +    +PH  ++H+DF  G  A + +Y   I
Sbjct: 343 DIVADPKDVENLLPQIANLIYYKLIPH--YNHVDFYLGEDAPQEIYQDLI 390


>AL358532-3|CAH71058.2|  399|Homo sapiens lipase, family member K
           protein.
          Length = 399

 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 20/59 (33%), Positives = 33/59 (55%)
 Frame = +3

Query: 279 FQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           F+ +C+N LF  +G      N + L V L H PAG +V+ + H+ Q +N+   + +D G
Sbjct: 251 FRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWG 309



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 22/53 (41%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G++RL+Y+GHSQGTT+ +   S  PE   KI    A APV  +++  + + KL
Sbjct: 162 GQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKL 214



 Score = 31.1 bits (67), Expect = 4.0
 Identities = 16/50 (32%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           DI AD +DV  L  ++   +    +PH  ++H+DF  G  A + +Y   I
Sbjct: 343 DIVADPKDVENLLPQIANLIYYKLIPH--YNHVDFYLGEDAPQEIYQDLI 390


>X05997-2|CAA29414.1|  392|Homo sapiens gastric lipase precursor
           protein.
          Length = 392

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 156 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 208



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 248 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 303


>X05997-1|CAA29413.1|  398|Homo sapiens gastric lipase precursor
           protein.
          Length = 398

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 162 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 214



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 254 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 309


>BC113711-1|AAI13712.1|  398|Homo sapiens lipase, gastric protein.
          Length = 398

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 162 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 214



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 254 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 309


>BC112272-1|AAI12273.1|  398|Homo sapiens lipase, gastric protein.
          Length = 398

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 162 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 214



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 254 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 309


>AY631869-1|AAT38115.1|  398|Homo sapiens lipase, gastric protein.
          Length = 398

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 162 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 214



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 254 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 309


>AL358532-2|CAH71056.1|  365|Homo sapiens lipase, gastric protein.
          Length = 365

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 129 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 181



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 221 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 276


>AL358532-1|CAH71057.1|  398|Homo sapiens lipase, gastric protein.
          Length = 398

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 162 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 214



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 254 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWG 309


>AK223468-1|BAD97188.1|  398|Homo sapiens lipase, gastric variant
           protein.
          Length = 398

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+++LHY+GHSQGTT+ +   S  P    +I    A APVA +++  + + KL
Sbjct: 162 GQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 214



 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+N LF   G      N + L V L H PAG +V+ + H+ Q + +  F+ YD G
Sbjct: 254 LCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQSMFHWTQAVKSGKFQAYDWG 309


>Z31690-1|CAA83495.1|  399|Homo sapiens lysosomal acid lipase
           protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>X76488-1|CAA54026.1|  399|Homo sapiens sterol esterase protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>U08464-1|AAB60328.1|  399|Homo sapiens lysosomal acid lipase
           protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>U04285-1|AAB60327.1|  399|Homo sapiens lysosomal acid
           lipase/cholesteryl ester hydrolase protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>M74775-1|AAA59519.1|  399|Homo sapiens lysosomal acid
           lipase/cholesteryl esterase protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>BC012287-1|AAH12287.1|  399|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>AL513533-3|CAI13517.1|  290|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 290

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264


>AL513533-2|CAI13516.1|  399|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>AL513533-1|CAI13515.1|  343|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 343

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 108 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 167

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 168 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 208



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 188 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 246

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 247 QKFQAFDWGSSAKNYFHY 264



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 289 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 336


>AL353751-4|CAI12237.1|  290|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 290

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264


>AL353751-3|CAI12236.1|  399|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>AL353751-1|CAI12234.1|  343|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 343

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 108 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 167

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 168 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 208



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 188 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 246

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 247 QKFQAFDWGSSAKNYFHY 264



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 289 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 336


>AL353146-2|CAI12380.1|  343|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 343

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 108 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 167

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 168 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 208



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 188 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 246

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 247 QKFQAFDWGSSAKNYFHY 264



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 289 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 336


>AK222760-1|BAD96480.1|  399|Homo sapiens lipase A precursor variant
           protein.
          Length = 399

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 223

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 224 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 264



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 244 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 302

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 303 QKFQAFDWGSSAKNYFHY 320



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 345 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 392


>AK125193-1|BAC86078.1|  401|Homo sapiens .  protein.
          Length = 401

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANS 180
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL     + 
Sbjct: 166 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHL 225

Query: 181 IEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSL 312
           I+    L G  E   +S F   +G            C  +C+ L
Sbjct: 226 IK---DLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLL 266



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 249 GNRFCADGVFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINN 428
           G   C   V  + +C N+ F   G +E   N + + V   H+PAG +V+ + H+ Q +  
Sbjct: 246 GTHVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKF 304

Query: 429 NFFRRYDHG-RLKNWRVY 479
             F+ +D G   KN+  Y
Sbjct: 305 QKFQAFDWGSSAKNYFHY 322



 Score = 31.9 bits (69), Expect = 2.3
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +2

Query: 551 DIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDRTI 700
           D  ADV DV  L  ++   V    +P   + HLDF+WG  A   LY++ I
Sbjct: 347 DWLADVYDVNILLTQITNLVFHESIPE--WEHLDFIWGLDAPWRLYNKII 394


>EF426483-1|ABR08388.1|  398|Homo sapiens lipase N protein.
          Length = 398

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/56 (32%), Positives = 31/56 (55%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+  +  +AG ++   N + + V + H P G +V  I H  QL +++ FR YD G
Sbjct: 255 ICSEFMSLWAGSNKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWG 310



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 15/45 (33%), Positives = 24/45 (53%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEF 135
           G+ +L++IGHS GTT+ +   S  PE   +I    A  P    ++
Sbjct: 163 GQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISFKY 207


>AL358532-5|CAH71060.2|  398|Homo sapiens lipase, family member N
           protein.
          Length = 398

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 18/56 (32%), Positives = 31/56 (55%)
 Frame = +3

Query: 288 MCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDHG 455
           +C+  +  +AG ++   N + + V + H P G +V  I H  QL +++ FR YD G
Sbjct: 255 ICSEFMSLWAGSNKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWG 310



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 15/45 (33%), Positives = 24/45 (53%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEF 135
           G+ +L++IGHS GTT+ +   S  PE   +I    A  P    ++
Sbjct: 163 GQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISFKY 207


>EF426484-1|ABR08389.1|  423|Homo sapiens lipase M protein.
          Length = 423

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 18/61 (29%), Positives = 31/61 (50%)
 Frame = +3

Query: 273 VFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDH 452
           V    +C+N++    G + +  N +   V   HT AG +V+ I H+ Q +N+   R +D 
Sbjct: 263 VILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDW 322

Query: 453 G 455
           G
Sbjct: 323 G 323



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLK-LIAPHAN 177
           G+ +++Y+G+SQGTT+ +   S  PE   KI    A AP+A ++   +   K L+ P   
Sbjct: 176 GQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDM- 234

Query: 178 SIEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSLLLDAVKTCTMRL 348
               +  L G  E   ++ F   + I         + C+ I   LLL    T  M +
Sbjct: 235 ---MIKGLFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNI--MLLLGGFNTNNMNM 286



 Score = 29.9 bits (64), Expect = 9.2
 Identities = 16/62 (25%), Positives = 30/62 (48%)
 Frame = +2

Query: 515 ITAPVFLHYVDDDIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDR 694
           +T P  +     D  ++  DV+ L  E+   +    +P   ++H+DF+WG  A   +Y+ 
Sbjct: 345 MTVPTAMWTGGQDWLSNPEDVKMLLSEVTNLIYHKNIPE--WAHVDFIWGLDAPHRMYNE 402

Query: 695 TI 700
            I
Sbjct: 403 II 404


>AL358532-7|CAO77925.1|  423|Homo sapiens lipase, family member M
           protein.
          Length = 423

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 18/61 (29%), Positives = 31/61 (50%)
 Frame = +3

Query: 273 VFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDH 452
           V    +C+N++    G + +  N +   V   HT AG +V+ I H+ Q +N+   R +D 
Sbjct: 263 VILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDW 322

Query: 453 G 455
           G
Sbjct: 323 G 323



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLK-LIAPHAN 177
           G+ +++Y+G+SQGTT+ +   S  PE   KI    A AP+A ++   +   K L+ P   
Sbjct: 176 GQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDM- 234

Query: 178 SIEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSLLLDAVKTCTMRL 348
               +  L G  E   ++ F   + I         + C+ I   LLL    T  M +
Sbjct: 235 ---MIKGLFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNI--MLLLGGFNTNNMNM 286



 Score = 29.9 bits (64), Expect = 9.2
 Identities = 16/62 (25%), Positives = 30/62 (48%)
 Frame = +2

Query: 515 ITAPVFLHYVDDDIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDR 694
           +T P  +     D  ++  DV+ L  E+   +    +P   ++H+DF+WG  A   +Y+ 
Sbjct: 345 MTVPTAMWTGGQDWLSNPEDVKMLLSEVTNLIYHKNIPE--WAHVDFIWGLDAPHRMYNE 402

Query: 695 TI 700
            I
Sbjct: 403 II 404


>AL353113-2|CAH72238.2|  423|Homo sapiens lipase, family member M
           protein.
          Length = 423

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 18/61 (29%), Positives = 31/61 (50%)
 Frame = +3

Query: 273 VFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINNNFFRRYDH 452
           V    +C+N++    G + +  N +   V   HT AG +V+ I H+ Q +N+   R +D 
Sbjct: 263 VILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDW 322

Query: 453 G 455
           G
Sbjct: 323 G 323



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLK-LIAPHAN 177
           G+ +++Y+G+SQGTT+ +   S  PE   KI    A AP+A ++   +   K L+ P   
Sbjct: 176 GQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDM- 234

Query: 178 SIEALTSLIGINELFGRSDFFTNVGIDFALMAYFSRRCAQICYSLLLDAVKTCTMRL 348
               +  L G  E   ++ F   + I         + C+ I   LLL    T  M +
Sbjct: 235 ---MIKGLFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNI--MLLLGGFNTNNMNM 286



 Score = 29.9 bits (64), Expect = 9.2
 Identities = 16/62 (25%), Positives = 30/62 (48%)
 Frame = +2

Query: 515 ITAPVFLHYVDDDIFADVRDVRKLQIELGRPVGMFRVPHATFSHLDFMWGSGAKELLYDR 694
           +T P  +     D  ++  DV+ L  E+   +    +P   ++H+DF+WG  A   +Y+ 
Sbjct: 345 MTVPTAMWTGGQDWLSNPEDVKMLLSEVTNLIYHKNIPE--WAHVDFIWGLDAPHRMYNE 402

Query: 695 TI 700
            I
Sbjct: 403 II 404


>AL353751-2|CAI12235.1|  219|Homo sapiens lipase A, lysosomal acid,
           cholesterol esterase (Wolman disease) protein.
          Length = 219

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 20/53 (37%), Positives = 31/53 (58%)
 Frame = +1

Query: 1   GKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 159
           G+ +++Y+GHSQGTT+ +   S  PE   +I    A  PVA + F  + + KL
Sbjct: 164 GQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKL 216


>BC022443-1|AAH22443.1|  192|Homo sapiens ZCCHC10 protein protein.
          Length = 192

 Score = 31.5 bits (68), Expect = 3.0
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = -2

Query: 369 VLVSQAT*SHCACLHCVQQKRITYLCTSPGKIRHQRKIYSHVRKEVRSAE 220
           +++S+A   H  C  C++    TY CT   K  H+    + ++K ++  E
Sbjct: 33  IVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKE 82


>EF186229-1|ABM67095.1|  451|Homo sapiens lipase H protein.
          Length = 451

 Score = 31.1 bits (67), Expect = 4.0
 Identities = 20/82 (24%), Positives = 37/82 (45%)
 Frame = +1

Query: 13  LHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEAL 192
           ++ IG S G  +   +G +   +  +I  +    P+   + + +RL    A   + I + 
Sbjct: 148 IYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD 207

Query: 193 TSLIGINELFGRSDFFTNVGID 258
           T  +G  E  G  DF+ N G+D
Sbjct: 208 TDALGYKEPLGNIDFYPNGGLD 229


>BC064941-1|AAH64941.1|  451|Homo sapiens lipase, member H protein.
          Length = 451

 Score = 31.1 bits (67), Expect = 4.0
 Identities = 20/82 (24%), Positives = 37/82 (45%)
 Frame = +1

Query: 13  LHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEAL 192
           ++ IG S G  +   +G +   +  +I  +    P+   + + +RL    A   + I + 
Sbjct: 148 IYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD 207

Query: 193 TSLIGINELFGRSDFFTNVGID 258
           T  +G  E  G  DF+ N G+D
Sbjct: 208 TDALGYKEPLGNIDFYPNGGLD 229


>AY093498-1|AAM18803.1|  451|Homo sapiens lipase H protein.
          Length = 451

 Score = 31.1 bits (67), Expect = 4.0
 Identities = 20/82 (24%), Positives = 37/82 (45%)
 Frame = +1

Query: 13  LHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEAL 192
           ++ IG S G  +   +G +   +  +I  +    P+   + + +RL    A   + I + 
Sbjct: 148 IYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD 207

Query: 193 TSLIGINELFGRSDFFTNVGID 258
           T  +G  E  G  DF+ N G+D
Sbjct: 208 TDALGYKEPLGNIDFYPNGGLD 229


>AY036912-1|AAK63178.1|  451|Homo sapiens membrane-bound
           phosphatidic acid-selective phospholipase A1 protein.
          Length = 451

 Score = 31.1 bits (67), Expect = 4.0
 Identities = 20/82 (24%), Positives = 37/82 (45%)
 Frame = +1

Query: 13  LHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEAL 192
           ++ IG S G  +   +G +   +  +I  +    P+   + + +RL    A   + I + 
Sbjct: 148 IYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD 207

Query: 193 TSLIGINELFGRSDFFTNVGID 258
           T  +G  E  G  DF+ N G+D
Sbjct: 208 TDALGYKEPLGNIDFYPNGGLD 229


>AK074229-1|BAB85023.1|  323|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23649 fis, clone COL06395, highly similar to
           Oryctolagus cuniculus lacrimal lipase mRNA. ).
          Length = 323

 Score = 31.1 bits (67), Expect = 4.0
 Identities = 20/82 (24%), Positives = 37/82 (45%)
 Frame = +1

Query: 13  LHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEAL 192
           ++ IG S G  +   +G +   +  +I  +    P+   + + +RL    A   + I + 
Sbjct: 20  IYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSD 79

Query: 193 TSLIGINELFGRSDFFTNVGID 258
           T  +G  E  G  DF+ N G+D
Sbjct: 80  TDALGYKEPLGNIDFYPNGGLD 101


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,115,650
Number of Sequences: 237096
Number of extensions: 2049955
Number of successful extensions: 3643
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 3500
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3643
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8119219030
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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