Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= mg--0351
(753 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 99 8e-21
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 99 8e-21
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 99 8e-21
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 99 8e-21
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 93 1e-18
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 93 1e-18
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 93 1e-18
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 93 1e-18
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 93 1e-18
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 93 1e-18
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 88 3e-17
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 88 3e-17
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 88 3e-17
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 88 3e-17
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 88 3e-17
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 79 2e-14
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 60 1e-08
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 60 1e-08
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 60 1e-08
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 57 6e-08
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 57 6e-08
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 57 6e-08
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 50 7e-06
BC066907-1|AAH66907.1| 452|Homo sapiens ethanolamine kinase 1 p... 32 1.9
BC025719-1|AAH25719.1| 390|Homo sapiens matrix metallopeptidase... 32 1.9
AL691432-6|CAM12835.1| 390|Homo sapiens matrix metallopeptidase... 32 1.9
AJ005256-1|CAB38176.1| 390|Homo sapiens MMP-23 protein. 32 1.9
AF207600-1|AAF71220.2| 452|Homo sapiens ethanolamine kinase pro... 32 1.9
AF057062-1|AAC62618.1| 249|Homo sapiens metalloprotease mmp21/2... 32 1.9
AF057061-1|AAC62617.1| 265|Homo sapiens metalloprotease mmp21/2... 32 1.9
AF056200-1|AAC62616.1| 390|Homo sapiens metalloprotease mmp21/2... 32 1.9
AF055334-3|AAC63529.1| 250|Homo sapiens metalloprotease isoform... 32 1.9
AF055334-2|AAC63528.1| 266|Homo sapiens metalloprotease isoform... 32 1.9
AF055334-1|AAC63527.1| 390|Homo sapiens metalloprotease isoform... 32 1.9
AB031068-1|BAA92769.1| 390|Homo sapiens MIFR/Femalysin protein. 32 1.9
AB010961-1|BAA24833.1| 390|Homo sapiens MIFR-1 protein. 32 1.9
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 99 bits (238), Expect = 8e-21
Identities = 44/77 (57%), Positives = 57/77 (74%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
VKD +TGDIA +SYH ++ D+ M+R L + YRFS+SWSRI P+G + IN GVDYYNR
Sbjct: 943 VKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNR 1002
Query: 204 LINEMLKYGITPMITLF 254
LIN ++ I PM+TLF
Sbjct: 1003 LINGLVASNIFPMVTLF 1019
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/80 (46%), Positives = 55/80 (68%)
Frame = +3
Query: 15 PAAVKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDY 194
P V++ + GD+A +SYH + D+ ++ LG+ YRFS+SWSRILP G INEAG++Y
Sbjct: 1413 PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNY 1472
Query: 195 YNRLINEMLKYGITPMITLF 254
Y RLI+ +L I P +T++
Sbjct: 1473 YVRLIDTLLAASIQPQVTIY 1492
Score = 73.7 bits (173), Expect = 6e-13
Identities = 34/73 (46%), Positives = 48/73 (65%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+T ++A++SYH V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+
Sbjct: 424 ATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDR 483
Query: 216 MLKYGITPMITLF 254
+ GI PM TLF
Sbjct: 484 LQDAGIEPMATLF 496
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P+ +Y L G + N F++YA V++ GD+VK WIT+NEP I Y+G
Sbjct: 1487 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 1546
Query: 415 YGSVHKAP-ILNATAIGTYL 471
YG AP + N Y+
Sbjct: 1547 YGYGTAAPGVSNRPGTAPYI 1566
Score = 50.8 bits (116), Expect = 5e-06
Identities = 24/63 (38%), Positives = 31/63 (49%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + NP F+ YA + FGDRVK W+T NEP + + G
Sbjct: 1014 PMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLG 1073
Query: 415 YGS 423
YGS
Sbjct: 1074 YGS 1076
Score = 49.6 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + N F DYA ++ FGDRVK W+T +EP + Y G
Sbjct: 491 PMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAG 550
Query: 415 YGSVHKAPILNATAIGTYLCARM 483
YG+ P ++ + ++ A +
Sbjct: 551 YGTGQHPPGISDPGVASFKVAHL 573
Score = 39.9 bits (89), Expect = 0.010
Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Frame = +2
Query: 236 PDDYFIHWDLPQKLQELGASPIHWLPFGLKT-TRAWSTRISVTES---NIGSP-LMSLEK 400
P HWDLPQ LQ++G + K R+ + P +++ +
Sbjct: 1487 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 1546
Query: 401 YATRVTALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSF 580
Y A +S+ P + +I + + HLYN+ ++ QGG ITIS++
Sbjct: 1547 YGYGTAA---PGVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWA 1603
Query: 581 RPFTDSEEDHAATELRRQAEF--GLYAEPIF 667
P S ++ RR +F G +A PIF
Sbjct: 1604 EPRDPSNQEDVEA-ARRYVQFMGGWFAHPIF 1633
Score = 35.5 bits (78), Expect = 0.21
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +3
Query: 117 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVIL 131
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 99 bits (238), Expect = 8e-21
Identities = 44/77 (57%), Positives = 57/77 (74%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
VKD +TGDIA +SYH ++ D+ M+R L + YRFS+SWSRI P+G + IN GVDYYNR
Sbjct: 943 VKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNR 1002
Query: 204 LINEMLKYGITPMITLF 254
LIN ++ I PM+TLF
Sbjct: 1003 LINGLVASNIFPMVTLF 1019
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/80 (46%), Positives = 55/80 (68%)
Frame = +3
Query: 15 PAAVKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDY 194
P V++ + GD+A +SYH + D+ ++ LG+ YRFS+SWSRILP G INEAG++Y
Sbjct: 1413 PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNY 1472
Query: 195 YNRLINEMLKYGITPMITLF 254
Y RLI+ +L I P +T++
Sbjct: 1473 YVRLIDTLLAASIQPQVTIY 1492
Score = 73.7 bits (173), Expect = 6e-13
Identities = 34/73 (46%), Positives = 48/73 (65%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+T ++A++SYH V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+
Sbjct: 424 ATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDR 483
Query: 216 MLKYGITPMITLF 254
+ GI PM TLF
Sbjct: 484 LQDAGIEPMATLF 496
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P+ +Y L G + N F++YA V++ GD+VK WIT+NEP I Y+G
Sbjct: 1487 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 1546
Query: 415 YGSVHKAP-ILNATAIGTYL 471
YG AP + N Y+
Sbjct: 1547 YGYGTAAPGVSNRPGTAPYI 1566
Score = 50.8 bits (116), Expect = 5e-06
Identities = 24/63 (38%), Positives = 31/63 (49%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + NP F+ YA + FGDRVK W+T NEP + + G
Sbjct: 1014 PMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLG 1073
Query: 415 YGS 423
YGS
Sbjct: 1074 YGS 1076
Score = 49.6 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + N F DYA ++ FGDRVK W+T +EP + Y G
Sbjct: 491 PMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAG 550
Query: 415 YGSVHKAPILNATAIGTYLCARM 483
YG+ P ++ + ++ A +
Sbjct: 551 YGTGQHPPGISDPGVASFKVAHL 573
Score = 39.9 bits (89), Expect = 0.010
Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Frame = +2
Query: 236 PDDYFIHWDLPQKLQELGASPIHWLPFGLKT-TRAWSTRISVTES---NIGSP-LMSLEK 400
P HWDLPQ LQ++G + K R+ + P +++ +
Sbjct: 1487 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 1546
Query: 401 YATRVTALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSF 580
Y A +S+ P + +I + + HLYN+ ++ QGG ITIS++
Sbjct: 1547 YGYGTAA---PGVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWA 1603
Query: 581 RPFTDSEEDHAATELRRQAEF--GLYAEPIF 667
P S ++ RR +F G +A PIF
Sbjct: 1604 EPRDPSNQEDVEA-ARRYVQFMGGWFAHPIF 1633
Score = 35.5 bits (78), Expect = 0.21
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +3
Query: 117 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVIL 131
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 99 bits (238), Expect = 8e-21
Identities = 44/77 (57%), Positives = 57/77 (74%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
VKD +TGDIA +SYH ++ D+ M+R L + YRFS+SWSRI P+G + IN GVDYYNR
Sbjct: 375 VKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNR 434
Query: 204 LINEMLKYGITPMITLF 254
LIN ++ I PM+TLF
Sbjct: 435 LINGLVASNIFPMVTLF 451
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/80 (46%), Positives = 55/80 (68%)
Frame = +3
Query: 15 PAAVKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDY 194
P V++ + GD+A +SYH + D+ ++ LG+ YRFS+SWSRILP G INEAG++Y
Sbjct: 845 PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNY 904
Query: 195 YNRLINEMLKYGITPMITLF 254
Y RLI+ +L I P +T++
Sbjct: 905 YVRLIDTLLAASIQPQVTIY 924
Score = 55.6 bits (128), Expect = 2e-07
Identities = 26/69 (37%), Positives = 37/69 (53%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P+ +Y L G + N F++YA V++ GD+VK WIT+NEP I Y+G
Sbjct: 919 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 978
Query: 415 YGSVHKAPI 441
YG AP+
Sbjct: 979 YGYGTAAPV 987
Score = 50.8 bits (116), Expect = 5e-06
Identities = 24/63 (38%), Positives = 31/63 (49%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + NP F+ YA + FGDRVK W+T NEP + + G
Sbjct: 446 PMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLG 505
Query: 415 YGS 423
YGS
Sbjct: 506 YGS 508
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 99 bits (238), Expect = 8e-21
Identities = 44/77 (57%), Positives = 57/77 (74%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
VKD +TGDIA +SYH ++ D+ M+R L + YRFS+SWSRI P+G + IN GVDYYNR
Sbjct: 943 VKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNR 1002
Query: 204 LINEMLKYGITPMITLF 254
LIN ++ I PM+TLF
Sbjct: 1003 LINGLVASNIFPMVTLF 1019
Score = 87.8 bits (208), Expect = 4e-17
Identities = 37/80 (46%), Positives = 55/80 (68%)
Frame = +3
Query: 15 PAAVKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDY 194
P V++ + GD+A +SYH + D+ ++ LG+ YRFS+SWSRILP G INEAG++Y
Sbjct: 1413 PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNY 1472
Query: 195 YNRLINEMLKYGITPMITLF 254
Y RLI+ +L I P +T++
Sbjct: 1473 YVRLIDTLLAASIQPQVTIY 1492
Score = 73.7 bits (173), Expect = 6e-13
Identities = 34/73 (46%), Positives = 48/73 (65%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+T ++A++SYH V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+
Sbjct: 424 ATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDR 483
Query: 216 MLKYGITPMITLF 254
+ GI PM TLF
Sbjct: 484 LQDAGIEPMATLF 496
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P+ +Y L G + N F++YA V++ GD+VK WIT+NEP I Y+G
Sbjct: 1487 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 1546
Query: 415 YGSVHKAP-ILNATAIGTYL 471
YG AP + N Y+
Sbjct: 1547 YGYGTAAPGVSNRPGTAPYI 1566
Score = 50.8 bits (116), Expect = 5e-06
Identities = 24/63 (38%), Positives = 31/63 (49%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + NP F+ YA + FGDRVK W+T NEP + + G
Sbjct: 1014 PMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLG 1073
Query: 415 YGS 423
YGS
Sbjct: 1074 YGS 1076
Score = 49.6 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 39/83 (46%)
Frame = +1
Query: 235 PR*LLYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEG 414
P L+ L G + N F DYA ++ FGDRVK W+T +EP + Y G
Sbjct: 491 PMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAG 550
Query: 415 YGSVHKAPILNATAIGTYLCARM 483
YG+ P ++ + ++ A +
Sbjct: 551 YGTGQHPPGISDPGVASFKVAHL 573
Score = 39.9 bits (89), Expect = 0.010
Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Frame = +2
Query: 236 PDDYFIHWDLPQKLQELGASPIHWLPFGLKT-TRAWSTRISVTES---NIGSP-LMSLEK 400
P HWDLPQ LQ++G + K R+ + P +++ +
Sbjct: 1487 PQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQG 1546
Query: 401 YATRVTALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSF 580
Y A +S+ P + +I + + HLYN+ ++ QGG ITIS++
Sbjct: 1547 YGYGTAA---PGVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWA 1603
Query: 581 RPFTDSEEDHAATELRRQAEF--GLYAEPIF 667
P S ++ RR +F G +A PIF
Sbjct: 1604 EPRDPSNQEDVEA-ARRYVQFMGGWFAHPIF 1633
Score = 35.5 bits (78), Expect = 0.21
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +3
Query: 117 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVIL 131
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 93.1 bits (221), Expect = 1e-18
Identities = 38/72 (52%), Positives = 56/72 (77%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEM 218
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
Query: 219 LKYGITPMITLF 254
LK G+TP++TL+
Sbjct: 108 LKNGVTPIVTLY 119
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/57 (35%), Positives = 27/57 (47%)
Frame = +1
Query: 247 LYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 417
LY L G + + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 93.1 bits (221), Expect = 1e-18
Identities = 38/72 (52%), Positives = 56/72 (77%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEM 218
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
Query: 219 LKYGITPMITLF 254
LK G+TP++TL+
Sbjct: 108 LKNGVTPIVTLY 119
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/57 (35%), Positives = 27/57 (47%)
Frame = +1
Query: 247 LYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 417
LY L G + + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 93.1 bits (221), Expect = 1e-18
Identities = 38/72 (52%), Positives = 56/72 (77%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEM 218
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
Query: 219 LKYGITPMITLF 254
LK G+TP++TL+
Sbjct: 108 LKNGVTPIVTLY 119
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/57 (35%), Positives = 27/57 (47%)
Frame = +1
Query: 247 LYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 417
LY L G + + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 93.1 bits (221), Expect = 1e-18
Identities = 38/72 (52%), Positives = 56/72 (77%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEM 218
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
Query: 219 LKYGITPMITLF 254
LK G+TP++TL+
Sbjct: 108 LKNGVTPIVTLY 119
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/57 (35%), Positives = 27/57 (47%)
Frame = +1
Query: 247 LYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 417
LY L G + + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 93.1 bits (221), Expect = 1e-18
Identities = 38/72 (52%), Positives = 56/72 (77%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEM 218
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
Query: 219 LKYGITPMITLF 254
LK G+TP++TL+
Sbjct: 108 LKNGVTPIVTLY 119
Score = 40.7 bits (91), Expect = 0.006
Identities = 20/57 (35%), Positives = 27/57 (47%)
Frame = +1
Query: 247 LYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 417
LY L G + + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 118 LYHFDLPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 93.1 bits (221), Expect = 1e-18
Identities = 38/72 (52%), Positives = 56/72 (77%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEM 218
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDL 107
Query: 219 LKYGITPMITLF 254
LK G+TP++TL+
Sbjct: 108 LKNGVTPIVTLY 119
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/57 (35%), Positives = 27/57 (47%)
Frame = +1
Query: 247 LYSLGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 417
LY L G + + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 118 LYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 88.2 bits (209), Expect = 3e-17
Identities = 36/73 (49%), Positives = 55/73 (75%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 216 MLKYGITPMITLF 254
+ + G+ P++TL+
Sbjct: 180 LRELGVQPVVTLY 192
Score = 50.0 bits (114), Expect = 9e-06
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGT 465
G +AN + F DYA + + +FG +VK+WITI+ P + + GY + AP + +
Sbjct: 205 GGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLG 264
Query: 466 YLCA 477
YL A
Sbjct: 265 YLVA 268
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 88.2 bits (209), Expect = 3e-17
Identities = 36/73 (49%), Positives = 55/73 (75%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 216 MLKYGITPMITLF 254
+ + G+ P++TL+
Sbjct: 180 LRELGVQPVVTLY 192
Score = 50.4 bits (115), Expect = 7e-06
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 72 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++ L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 252 F 254
+
Sbjct: 638 W 638
Score = 50.0 bits (114), Expect = 9e-06
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGT 465
G +AN + F DYA + + +FG +VK+WITI+ P + + GY + AP + +
Sbjct: 205 GGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLG 264
Query: 466 YLCA 477
YL A
Sbjct: 265 YLVA 268
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 8/146 (5%)
Frame = +2
Query: 254 HWDLPQKLQEL------GASPIHWLPFGLKTTRAWSTRISVTESNIGSPLMSLEKYATRV 415
HWDLPQ+LQ+ A H+ + R + ++ + +++ YAT
Sbjct: 193 HWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGR 252
Query: 416 TALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSFRPFTD 595
A I+ +PR G++ + HLYN F+ QGGQ I +S++ P
Sbjct: 253 LAPGIR---GSPR-LGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINP--R 306
Query: 596 SEEDHAATELRRQAEF--GLYAEPIF 667
DH+ E ++ +F G +A+P+F
Sbjct: 307 RMTDHSIKECQKSLDFVLGWFAKPVF 332
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Frame = +1
Query: 259 GLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REICYEGYGSVHK 432
GL A G++ NP ++ F +YAR+ + G VK WIT+NEP R + Y ++ K
Sbjct: 646 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLK 705
Query: 433 APIL 444
A L
Sbjct: 706 AHAL 709
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 88.2 bits (209), Expect = 3e-17
Identities = 36/73 (49%), Positives = 55/73 (75%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 216 MLKYGITPMITLF 254
+ + G+ P++TL+
Sbjct: 180 LRELGVQPVVTLY 192
Score = 50.0 bits (114), Expect = 9e-06
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGT 465
G +AN + F DYA + + +FG +VK+WITI+ P + + GY + AP + +
Sbjct: 205 GGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLG 264
Query: 466 YLCA 477
YL A
Sbjct: 265 YLVA 268
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 8/146 (5%)
Frame = +2
Query: 254 HWDLPQKLQEL------GASPIHWLPFGLKTTRAWSTRISVTESNIGSPLMSLEKYATRV 415
HWDLPQ+LQ+ A H+ + R + ++ + +++ YAT
Sbjct: 193 HWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGR 252
Query: 416 TALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSFRPFTD 595
A I+ +PR G++ + HLYN F+ QGGQ I +S++ P
Sbjct: 253 LAPGIR---GSPR-LGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINP--R 306
Query: 596 SEEDHAATELRRQAEF--GLYAEPIF 667
DH+ E ++ +F G +A+P+F
Sbjct: 307 RMTDHSIKECQKSLDFVLGWFAKPVF 332
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 88.2 bits (209), Expect = 3e-17
Identities = 36/73 (49%), Positives = 55/73 (75%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 216 MLKYGITPMITLF 254
+ + G+ P++TL+
Sbjct: 180 LRELGVQPVVTLY 192
Score = 50.4 bits (115), Expect = 7e-06
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 72 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++ L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 252 F 254
+
Sbjct: 638 W 638
Score = 50.0 bits (114), Expect = 9e-06
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGT 465
G +AN + F DYA + + +FG +VK+WITI+ P + + GY + AP + +
Sbjct: 205 GGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLG 264
Query: 466 YLCA 477
YL A
Sbjct: 265 YLVA 268
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 8/146 (5%)
Frame = +2
Query: 254 HWDLPQKLQEL------GASPIHWLPFGLKTTRAWSTRISVTESNIGSPLMSLEKYATRV 415
HWDLPQ+LQ+ A H+ + R + ++ + +++ YAT
Sbjct: 193 HWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGR 252
Query: 416 TALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSFRPFTD 595
A I+ +PR G++ + HLYN F+ QGGQ I +S++ P
Sbjct: 253 LAPGIR---GSPR-LGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINP--R 306
Query: 596 SEEDHAATELRRQAEF--GLYAEPIF 667
DH+ E ++ +F G +A+P+F
Sbjct: 307 RMTDHSIKECQKSLDFVLGWFAKPVF 332
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Frame = +1
Query: 259 GLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REICYEGYGSVHK 432
GL A G++ NP ++ F +YAR+ + G VK WIT+NEP R + Y ++ K
Sbjct: 646 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLK 705
Query: 433 APIL 444
A L
Sbjct: 706 AHAL 709
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 88.2 bits (209), Expect = 3e-17
Identities = 36/73 (49%), Positives = 55/73 (75%)
Frame = +3
Query: 36 STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINE 215
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 216 MLKYGITPMITLF 254
+ + G+ P++TL+
Sbjct: 180 LRELGVQPVVTLY 192
Score = 50.4 bits (115), Expect = 7e-06
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 72 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++ L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 252 F 254
+
Sbjct: 638 W 638
Score = 50.0 bits (114), Expect = 9e-06
Identities = 23/64 (35%), Positives = 36/64 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGT 465
G +AN + F DYA + + +FG +VK+WITI+ P + + GY + AP + +
Sbjct: 205 GGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLG 264
Query: 466 YLCA 477
YL A
Sbjct: 265 YLVA 268
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 8/146 (5%)
Frame = +2
Query: 254 HWDLPQKLQEL------GASPIHWLPFGLKTTRAWSTRISVTESNIGSPLMSLEKYATRV 415
HWDLPQ+LQ+ A H+ + R + ++ + +++ YAT
Sbjct: 193 HWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGR 252
Query: 416 TALFIKHLSSTPRPSGHICVQECFDSPR*SIHLYNNEFKDKQGGQCGITISANSFRPFTD 595
A I+ +PR G++ + HLYN F+ QGGQ I +S++ P
Sbjct: 253 LAPGIR---GSPR-LGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINP--R 306
Query: 596 SEEDHAATELRRQAEF--GLYAEPIF 667
DH+ E ++ +F G +A+P+F
Sbjct: 307 RMTDHSIKECQKSLDFVLGWFAKPVF 332
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Frame = +1
Query: 259 GLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REICYEGYGSVHK 432
GL A G++ NP ++ F +YAR+ + G VK WIT+NEP R + Y ++ K
Sbjct: 646 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLK 705
Query: 433 APIL 444
A L
Sbjct: 706 AHAL 709
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 79.0 bits (186), Expect = 2e-14
Identities = 33/77 (42%), Positives = 55/77 (71%), Gaps = 1/77 (1%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGF-ANEINEAGVDYYN 200
V T D+A + Y+ V+ D+ ++REL ++ YRFSLSW R+LP+G A ++N+ G+++Y+
Sbjct: 77 VLGNETADVACDGYYKVQEDIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYS 136
Query: 201 RLINEMLKYGITPMITL 251
LI+ +L ITP++TL
Sbjct: 137 DLIDALLSSNITPIVTL 153
Score = 61.3 bits (142), Expect = 4e-09
Identities = 27/64 (42%), Positives = 37/64 (57%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGT 465
G + N + +F DYA + + FGDRVKHWIT ++PR + +GY + H AP L G
Sbjct: 167 GGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHAPGLKLRGTGL 226
Query: 466 YLCA 477
Y A
Sbjct: 227 YKAA 230
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/77 (31%), Positives = 49/77 (63%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
+K+ S+ + +++SY +E+D+ + +G+ Y+FS+SW R+ P G N G+ YY+
Sbjct: 118 LKNVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYST 177
Query: 204 LINEMLKYGITPMITLF 254
L++ ++ I P++TL+
Sbjct: 178 LLDALVLRNIEPIVTLY 194
Score = 58.8 bits (136), Expect = 2e-08
Identities = 23/65 (35%), Positives = 43/65 (66%)
Frame = +3
Query: 69 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 248
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 249 LFTGT 263
L+ T
Sbjct: 641 LYYPT 645
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/51 (43%), Positives = 29/51 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 438
G + N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 207 GGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +1
Query: 256 LGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREIC-------YEG 414
LGL + NP + F+ YA + + GD VK WITINEP + +
Sbjct: 649 LGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDT 708
Query: 415 YGSVHKAPILNATAIGTY 468
YG+ H + +A A Y
Sbjct: 709 YGAAHNLLVAHALAWRLY 726
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/77 (31%), Positives = 49/77 (63%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
+K+ S+ + +++SY +E+D+ + +G+ Y+FS+SW R+ P G N G+ YY+
Sbjct: 118 LKNVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYST 177
Query: 204 LINEMLKYGITPMITLF 254
L++ ++ I P++TL+
Sbjct: 178 LLDALVLRNIEPIVTLY 194
Score = 58.8 bits (136), Expect = 2e-08
Identities = 23/65 (35%), Positives = 43/65 (66%)
Frame = +3
Query: 69 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 248
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 249 LFTGT 263
L+ T
Sbjct: 641 LYYPT 645
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/51 (43%), Positives = 29/51 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 438
G + N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 207 GGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +1
Query: 256 LGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREIC-------YEG 414
LGL + NP + F+ YA + + GD VK WITINEP + +
Sbjct: 649 LGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDT 708
Query: 415 YGSVHKAPILNATAIGTY 468
YG+ H + +A A Y
Sbjct: 709 YGAAHNLLVAHALAWRLY 726
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 59.7 bits (138), Expect = 1e-08
Identities = 24/77 (31%), Positives = 49/77 (63%)
Frame = +3
Query: 24 VKDGSTGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNR 203
+K+ S+ + +++SY +E+D+ + +G+ Y+FS+SW R+ P G N G+ YY+
Sbjct: 118 LKNVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYST 177
Query: 204 LINEMLKYGITPMITLF 254
L++ ++ I P++TL+
Sbjct: 178 LLDALVLRNIEPIVTLY 194
Score = 58.8 bits (136), Expect = 2e-08
Identities = 23/65 (35%), Positives = 43/65 (66%)
Frame = +3
Query: 69 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 248
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 249 LFTGT 263
L+ T
Sbjct: 641 LYYPT 645
Score = 49.2 bits (112), Expect = 2e-05
Identities = 22/51 (43%), Positives = 29/51 (56%)
Frame = +1
Query: 286 GSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 438
G + N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 207 GGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Frame = +1
Query: 256 LGLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREIC-------YEG 414
LGL + NP + F+ YA + + GD VK WITINEP + +
Sbjct: 649 LGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDT 708
Query: 415 YGSVHKAPILNATAIGTY 468
YG+ H + +A A Y
Sbjct: 709 YGAAHNLLVAHALAWRLY 726
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 57.2 bits (132), Expect = 6e-08
Identities = 25/50 (50%), Positives = 34/50 (68%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 188
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 57.2 bits (132), Expect = 6e-08
Identities = 25/50 (50%), Positives = 34/50 (68%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 188
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 57.2 bits (132), Expect = 6e-08
Identities = 25/50 (50%), Positives = 34/50 (68%)
Frame = +3
Query: 39 TGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 188
TGD+A SY E D++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 48 TGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 50.4 bits (115), Expect = 7e-06
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 72 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 251
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++ L
Sbjct: 305 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 364
Query: 252 F 254
+
Sbjct: 365 W 365
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Frame = +1
Query: 259 GLASEAAGTGSFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REICYEGYGSVHK 432
GL A G++ NP ++ F +YAR+ + G VK WIT+NEP R + Y ++ K
Sbjct: 373 GLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLK 432
Query: 433 APIL 444
A L
Sbjct: 433 AHAL 436
Score = 40.7 bits (91), Expect = 0.006
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Frame = +2
Query: 509 HLYNNEFKDKQGGQCGITISANSFRPFTDSEEDHAATELRRQAEF--GLYAEPIF 667
HLYN F+ QGGQ I +S++ P DH+ E ++ +F G +A+P+F
Sbjct: 7 HLYNTSFRPTQGGQVSIALSSHWINP--RRMTDHSIKECQKSLDFVLGWFAKPVF 59
>BC066907-1|AAH66907.1| 452|Homo sapiens ethanolamine kinase 1
protein.
Length = 452
Score = 32.3 bits (70), Expect = 1.9
Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
Frame = -3
Query: 577 RIGTDGDTALSSLFVL----ELIVVQVYALAWAIKTFLH 473
R GT+G T+LS+ VL ++VV V A+AWA+ ++H
Sbjct: 57 RPGTEGSTSLSAPAVLVVAVAVVVVVVSAVAWAMANYIH 95
>BC025719-1|AAH25719.1| 390|Homo sapiens matrix metallopeptidase
23B protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AL691432-6|CAM12835.1| 390|Homo sapiens matrix metallopeptidase
23B protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AJ005256-1|CAB38176.1| 390|Homo sapiens MMP-23 protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AF207600-1|AAF71220.2| 452|Homo sapiens ethanolamine kinase
protein.
Length = 452
Score = 32.3 bits (70), Expect = 1.9
Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
Frame = -3
Query: 577 RIGTDGDTALSSLFVL----ELIVVQVYALAWAIKTFLH 473
R GT+G T+LS+ VL ++VV V A+AWA+ ++H
Sbjct: 57 RPGTEGSTSLSAPAVLVVAVAVVVVVVSAVAWAMANYIH 95
>AF057062-1|AAC62618.1| 249|Homo sapiens metalloprotease mmp21/22C
protein.
Length = 249
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 210 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 247
>AF057061-1|AAC62617.1| 265|Homo sapiens metalloprotease mmp21/22B
protein.
Length = 265
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 226 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 263
>AF056200-1|AAC62616.1| 390|Homo sapiens metalloprotease mmp21/22A
protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AF055334-3|AAC63529.1| 250|Homo sapiens metalloprotease isoform C
protein.
Length = 250
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 210 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 247
>AF055334-2|AAC63528.1| 266|Homo sapiens metalloprotease isoform B
protein.
Length = 266
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 226 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 263
>AF055334-1|AAC63527.1| 390|Homo sapiens metalloprotease isoform A
protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AB031068-1|BAA92769.1| 390|Homo sapiens MIFR/Femalysin protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AB010961-1|BAA24833.1| 390|Homo sapiens MIFR-1 protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +1
Query: 370 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 474
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,817,344
Number of Sequences: 237096
Number of extensions: 2066145
Number of successful extensions: 4060
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 3836
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4042
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9071127468
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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