Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= mg--0308
(573 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 103 2e-21
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 99 8e-20
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 98 1e-19
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 97 3e-19
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 96 5e-19
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 95 8e-19
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 95 1e-18
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 94 2e-18
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 94 2e-18
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 92 7e-18
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 89 7e-17
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 89 7e-17
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 86 5e-16
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 86 5e-16
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 86 6e-16
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 86 6e-16
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 85 8e-16
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 85 1e-15
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 85 1e-15
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 84 3e-15
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 84 3e-15
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 83 6e-15
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 82 8e-15
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 81 1e-14
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 81 2e-14
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 80 3e-14
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 80 3e-14
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 80 4e-14
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 79 6e-14
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 79 7e-14
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 79 1e-13
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 79 1e-13
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 77 2e-13
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 76 7e-13
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 76 7e-13
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 76 7e-13
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 75 2e-12
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 75 2e-12
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 73 4e-12
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 73 5e-12
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 5e-12
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 73 6e-12
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 73 6e-12
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 73 6e-12
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 73 6e-12
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 72 8e-12
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 72 8e-12
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 72 8e-12
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 72 1e-11
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 72 1e-11
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 72 1e-11
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 71 1e-11
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 71 1e-11
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 71 2e-11
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 71 2e-11
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 71 2e-11
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 71 3e-11
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 71 3e-11
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 70 3e-11
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 70 3e-11
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 70 3e-11
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 70 4e-11
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 70 4e-11
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 70 4e-11
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 69 6e-11
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 69 6e-11
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 69 8e-11
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 69 1e-10
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 1e-10
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 1e-10
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 68 1e-10
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 68 1e-10
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 1e-10
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 2e-10
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 68 2e-10
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 68 2e-10
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 67 2e-10
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 67 2e-10
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 67 2e-10
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 67 3e-10
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 67 3e-10
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 67 3e-10
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 67 3e-10
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 66 6e-10
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 6e-10
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 7e-10
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 7e-10
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 66 7e-10
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 66 7e-10
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 65 1e-09
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 65 1e-09
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 65 1e-09
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 65 1e-09
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 64 2e-09
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 64 2e-09
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 64 3e-09
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 63 4e-09
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 5e-09
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 63 5e-09
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 62 7e-09
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 62 7e-09
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 7e-09
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 7e-09
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 62 7e-09
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 62 7e-09
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 9e-09
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 62 9e-09
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 62 9e-09
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 62 1e-08
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 61 2e-08
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 60 3e-08
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 60 3e-08
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 60 4e-08
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 60 5e-08
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 60 5e-08
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 60 5e-08
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 59 6e-08
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 59 6e-08
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 59 6e-08
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 59 8e-08
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 59 8e-08
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 8e-08
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 58 1e-07
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 58 1e-07
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 1e-07
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 58 1e-07
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 58 1e-07
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 58 1e-07
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 58 2e-07
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 58 2e-07
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 57 3e-07
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 57 3e-07
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 57 3e-07
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 3e-07
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 57 3e-07
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 56 4e-07
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 56 4e-07
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 56 4e-07
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 56 6e-07
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 56 6e-07
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 56 6e-07
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 56 8e-07
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 56 8e-07
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 8e-07
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 8e-07
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 55 1e-06
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 55 1e-06
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 55 1e-06
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 55 1e-06
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 55 1e-06
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 55 1e-06
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 55 1e-06
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 54 2e-06
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 54 2e-06
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_A1WS34 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 54 2e-06
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 54 2e-06
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 2e-06
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 54 3e-06
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 54 3e-06
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 3e-06
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 53 4e-06
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 4e-06
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 53 4e-06
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 53 6e-06
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 52 7e-06
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 52 7e-06
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 52 1e-05
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 52 1e-05
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 52 1e-05
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 1e-05
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 52 1e-05
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 1e-05
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 1e-05
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 51 2e-05
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 51 2e-05
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 51 2e-05
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 51 2e-05
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 50 3e-05
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 50 4e-05
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 4e-05
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 50 4e-05
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 50 5e-05
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 50 5e-05
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 50 5e-05
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 49 7e-05
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 49 7e-05
UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;... 48 1e-04
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 1e-04
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 48 1e-04
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 48 2e-04
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 48 2e-04
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 2e-04
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 47 3e-04
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 4e-04
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 46 5e-04
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 46 6e-04
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 46 6e-04
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 46 6e-04
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 46 6e-04
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 46 8e-04
UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 45 0.001
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 45 0.001
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 45 0.001
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 45 0.001
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 45 0.001
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 44 0.003
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 44 0.003
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 44 0.003
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 44 0.003
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 43 0.004
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 43 0.004
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 43 0.004
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 43 0.006
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.006
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 42 0.008
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 42 0.014
UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 41 0.018
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 41 0.024
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 40 0.031
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.031
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 40 0.031
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 40 0.031
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 40 0.041
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 40 0.055
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.055
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.055
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 39 0.072
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 39 0.072
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.072
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 39 0.072
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 39 0.072
UniRef50_A1C8I6 Cluster: NAD binding NADP oxidoreductase coenzym... 39 0.096
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 38 0.13
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 38 0.13
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 38 0.13
UniRef50_Q5LQS2 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 38 0.17
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 38 0.22
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 37 0.29
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 36 0.51
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.51
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 36 0.51
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 36 0.68
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 36 0.68
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 36 0.89
UniRef50_Q7R2L6 Cluster: GLP_546_59207_56595; n=2; Giardia intes... 36 0.89
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.89
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 35 1.2
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 35 1.6
UniRef50_A6T947 Cluster: Putative dehydrogenase; n=1; Klebsiella... 35 1.6
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 2.1
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 2.1
UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 34 2.1
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 2.1
UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma hydr... 34 2.7
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 34 2.7
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 2.7
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 33 3.6
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 3.6
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 33 3.6
UniRef50_Q4SP00 Cluster: Chromosome 15 SCAF14542, whole genome s... 33 4.8
UniRef50_Q24SE7 Cluster: Putative uncharacterized protein; n=2; ... 33 4.8
UniRef50_UPI00003650C0 Cluster: patched domain containing 3; n=1... 33 6.3
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 33 6.3
UniRef50_Q82PV0 Cluster: Putative GntR-family transcriptional re... 33 6.3
UniRef50_Q9RNC5 Cluster: Putative 3-hydroxyacid dehydrogenase; n... 33 6.3
UniRef50_UPI0000F1E276 Cluster: PREDICTED: similar to G protein-... 32 8.3
UniRef50_Q1AYM7 Cluster: GntR-like protein; n=1; Rubrobacter xyl... 32 8.3
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 32 8.3
UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 32 8.3
UniRef50_Q9SHQ3 Cluster: F1K23.11; n=12; core eudicotyledons|Rep... 32 8.3
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 32 8.3
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 103 bits (248), Expect = 2e-21
Identities = 48/83 (57%), Positives = 59/83 (71%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA+ TL FM GG K+ + PIL MGA HCG G+GQ+AKL NN++
Sbjct: 138 DAPVSGGVTGAEAGTLTFMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKLCNNLI 197
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ IT + T E MN+GIKMGL+PK
Sbjct: 198 LAITMIGTCEGMNLGIKMGLDPK 220
Score = 92.7 bits (220), Expect = 6e-18
Identities = 41/82 (50%), Positives = 55/82 (67%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
++N S+ RSWS++ Y PVPGL+ P S +Y GGF L+ KDL LA G+AL +P+PL
Sbjct: 225 IINVSTGRSWSSQTYNPVPGLIEKIPPSNDYKGGFAVNLVAKDLGLAEGVALLCNAPVPL 284
Query: 441 GAVATQLYRIVQSRGYGQKDFS 506
A A Q+YR + GYG KDF+
Sbjct: 285 TAAAHQIYRALSCNGYGNKDFA 306
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 98.7 bits (235), Expect = 8e-20
Identities = 41/84 (48%), Positives = 65/84 (77%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
+++N+S+ R W++E+Y PVPG+ P+AP++R+Y GGF + L+ KDL LASG+A SPIP
Sbjct: 229 EIINSSTGRCWASEIYNPVPGVCPSAPANRDYAGGFSSALITKDLGLASGVANASNSPIP 288
Query: 438 LGAVATQLYRIVQSRGYGQKDFSL 509
LG++A ++Y+ + +G G KDFS+
Sbjct: 289 LGSLAHKVYQSLCDKGLGNKDFSV 312
Score = 90.2 bits (214), Expect = 3e-17
Identities = 40/85 (47%), Positives = 55/85 (64%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA+ ATL FM GG + ++ +L+ MG K HCG G GQ AKL NNM+
Sbjct: 143 DAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAKLCNNMM 202
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+ I+ + +E MN+ ++ GL+ F
Sbjct: 203 LAISMIGVSEAMNLAVRQGLDANVF 227
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 98.3 bits (234), Expect = 1e-19
Identities = 41/83 (49%), Positives = 59/83 (71%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG GA+ TL FM GG ++DF + L+ MG HCG +G+GQVAK+ NN++
Sbjct: 139 DCPVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVCNNLV 198
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI+ +A +E MN+G+K G++PK
Sbjct: 199 LGISMIAVSEAMNLGVKQGMDPK 221
Score = 90.2 bits (214), Expect = 3e-17
Identities = 42/83 (50%), Positives = 57/83 (68%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
+ N SSAR W++E+Y P PG++ T+P+SR Y GGF + LM KDL LA A I P+ L
Sbjct: 226 IFNTSSARCWTSELYNPCPGVIETSPASRGYTGGFGSALMTKDLGLAVDSAKSIGEPLLL 285
Query: 441 GAVATQLYRIVQSRGYGQKDFSL 509
G A QLY ++ ++G GQKDFS+
Sbjct: 286 GNSAHQLYTLLVAKGDGQKDFSV 308
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 96.7 bits (230), Expect = 3e-19
Identities = 44/82 (53%), Positives = 58/82 (70%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
++N S+ R WS++ Y P PG++ TAPSSR Y GGF +LM+KDL LA+ A R P+ L
Sbjct: 204 IVNTSTGRCWSSDTYNPYPGVIDTAPSSRGYSGGFGTDLMLKDLGLANDAAKQARQPVYL 263
Query: 441 GAVATQLYRIVQSRGYGQKDFS 506
GA+A QLY+ + SRG GQ DFS
Sbjct: 264 GALAQQLYQTMSSRGDGQLDFS 285
Score = 95.9 bits (228), Expect = 6e-19
Identities = 43/83 (51%), Positives = 56/83 (67%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA TL FM GG DFER P+L MG HCG G GQVAK+ NN++
Sbjct: 117 DAPVSGGTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKVCNNLV 176
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI+ A +E M++G+ +G++PK
Sbjct: 177 LGISMAAVSEAMSLGVALGIDPK 199
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 96.3 bits (229), Expect = 5e-19
Identities = 45/82 (54%), Positives = 58/82 (70%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA+ TL+F+ GG E F R+ P+L+ MG FH G G+GQVAK+ NNML
Sbjct: 118 DAPVSGGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNML 177
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+GI TAE + +G+K GL+P
Sbjct: 178 LGILMAGTAEALALGVKNGLDP 199
Score = 66.1 bits (154), Expect = 6e-10
Identities = 30/71 (42%), Positives = 45/71 (63%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
+V+ SS +W+ +Y P PG++P AP+S Y GGF+ LM KDL LA A +++ P
Sbjct: 204 EVMKQSSGGNWALNLYNPWPGVMPQAPASNGYAGGFQVRLMNKDLGLALANAQAVQASTP 263
Query: 438 LGAVATQLYRI 470
LGA+A L+ +
Sbjct: 264 LGALARNLFSL 274
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 95.5 bits (227), Expect = 8e-19
Identities = 41/87 (47%), Positives = 61/87 (70%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV A++ L FM GG +++F + +L MG+ +CG +G+GQ AK+ NNML
Sbjct: 156 DAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNML 215
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGR 262
+ I+ + TAE MN+GI++GL+PK +
Sbjct: 216 LAISMIGTAEAMNLGIRLGLDPKLLAK 242
Score = 93.5 bits (222), Expect = 3e-18
Identities = 42/82 (51%), Positives = 57/82 (69%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
+LN SS R WS++ Y PVPG++ PS+ NY GGF LM KDL LA A +SPI L
Sbjct: 243 ILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILL 302
Query: 441 GAVATQLYRIVQSRGYGQKDFS 506
G++A Q+YR++ ++GY +KDFS
Sbjct: 303 GSLAHQIYRMMCAKGYSKKDFS 324
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 94.7 bits (225), Expect = 1e-18
Identities = 43/83 (51%), Positives = 54/83 (65%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA TL F+ GG ED + P+L+ MG FH G G+GQ AK+ NNML
Sbjct: 118 DAPVSGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNML 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI TAE + +G+K GL+PK
Sbjct: 178 LGILMAGTAEALALGVKNGLDPK 200
Score = 82.2 bits (194), Expect = 8e-15
Identities = 39/83 (46%), Positives = 55/83 (66%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
++++ SS R+W+TE+Y P PG++ P+SR Y GGF +ELM+KDL LA AL + P
Sbjct: 204 EIISKSSGRNWATELYNPWPGVMDNTPASRGYAGGFMSELMLKDLGLAEETALQSHAANP 263
Query: 438 LGAVATQLYRIVQSRGYGQKDFS 506
LGA+A LY +G G+ DFS
Sbjct: 264 LGALARNLYEEHVHQGNGKLDFS 286
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 93.9 bits (223), Expect = 2e-18
Identities = 42/84 (50%), Positives = 58/84 (69%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
D++N S+ R WS+EV PVPG+ PT PSS +Y GGF L+ KDL LA A +SPI
Sbjct: 181 DIVNTSTGRCWSSEVNNPVPGISPTVPSSNDYAGGFGTSLIAKDLGLAQAAATRAKSPIA 240
Query: 438 LGAVATQLYRIVQSRGYGQKDFSL 509
LG+++ Q+YR +++ G G KDFS+
Sbjct: 241 LGSLSHQIYRTMEAHGLGGKDFSV 264
Score = 54.8 bits (126), Expect = 1e-06
Identities = 22/44 (50%), Positives = 32/44 (72%)
Frame = +2
Query: 119 KQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 250
K HCG G GQVAK+ NNML+ I+ + +E +++G K+GL+PK
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLGEKLGLDPK 177
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 93.9 bits (223), Expect = 2e-18
Identities = 43/83 (51%), Positives = 57/83 (68%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGVMGA+ TL FM GG ED ER+ P+L+ MG + FH G+ G GQ AKL NN+L
Sbjct: 118 DAPVSGGVMGAEAGTLTFMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLL 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
GI+ +A +E + +GL+ +
Sbjct: 178 AGISMIAVSEAFALARHLGLDAR 200
Score = 70.1 bits (164), Expect = 3e-11
Identities = 34/78 (43%), Positives = 48/78 (61%)
Frame = +3
Query: 273 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVA 452
S+ +S Y PVPGLVP PSSR Y GF ++LM+KDL+LA A+ + +PLG +A
Sbjct: 209 STGGCFSLTNYPPVPGLVPNVPSSREYRNGFASQLMLKDLKLAQQAAIQSGTALPLGGLA 268
Query: 453 TQLYRIVQSRGYGQKDFS 506
LY + G+ + D+S
Sbjct: 269 AALYGMFCQAGHSELDYS 286
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 92.3 bits (219), Expect = 7e-18
Identities = 45/85 (52%), Positives = 53/85 (62%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG++GAQNATL FM GG KE FER + MG K H G G G + KL NNML
Sbjct: 118 DAPVSGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLIIKLINNML 177
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+GI +A +E N K G+ K F
Sbjct: 178 LGINMIAASEACNFAEKTGINLKTF 202
Score = 53.2 bits (122), Expect = 4e-06
Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
D++ +S+ SW+ P+P ++ P++ +Y GF L++KD+ +A A +
Sbjct: 204 DIVASSTGSSWAFNKNFPMPDIIENVPANNDYKPGFGAPLIMKDINIAVETAQDYNINLK 263
Query: 438 LGAVATQLY-RIVQSRGYGQKDFS 506
LG +A ++Y R++ S +KDFS
Sbjct: 264 LGLLAKEIYERMINSEELNKKDFS 287
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 89.0 bits (211), Expect = 7e-17
Identities = 41/83 (49%), Positives = 57/83 (68%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV A+ A L FM GG KEDFER+ +L ++G K + G G+G AK+ NNML
Sbjct: 118 DAPVSGGVAAAEAAGLTFMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAAKICNNML 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI+ +A +E + K+GL+P+
Sbjct: 178 LGISMIAVSEAFVLADKLGLDPQ 200
Score = 70.9 bits (166), Expect = 2e-11
Identities = 32/83 (38%), Positives = 48/83 (57%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
++ +N+S WS YCP PG++ PSS Y GF ++M+KDL L+ A ++ P
Sbjct: 204 EISSNASGECWSLTHYCPWPGILKDVPSSHEYKPGFTAKMMLKDLNLSQAAASDAKANTP 263
Query: 438 LGAVATQLYRIVQSRGYGQKDFS 506
LG AT+LY+ +G+ DFS
Sbjct: 264 LGKRATELYQQFVDSDHGEVDFS 286
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 89.0 bits (211), Expect = 7e-17
Identities = 41/83 (49%), Positives = 54/83 (65%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG +GA N TL M GG DFE +LP+LK +G K HCG GSGQ KL N +L
Sbjct: 122 DAPVTGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVL 181
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
GI +A AE + + ++G+ P+
Sbjct: 182 CGIHAIAAAEAIQLSEQLGIAPE 204
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 86.2 bits (204), Expect = 5e-16
Identities = 44/100 (44%), Positives = 63/100 (63%), Gaps = 1/100 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+ TL+ M GG +EDF R+ P+ +VMG H G G+GQ+ K N ++
Sbjct: 132 DAPVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQIVKAANQIV 191
Query: 182 MGITGMATAECMNMGIKMGLEP-KFFGRAEQLIGSLLVDR 298
+G+T A E + +G++ G+EP K F E L G L +R
Sbjct: 192 VGLTIEAVCEALVLGLRGGVEPQKIF---EVLCGGLAANR 228
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 86.2 bits (204), Expect = 5e-16
Identities = 43/81 (53%), Positives = 53/81 (65%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG +GA+ TL MAGG+ DFERSLP+LKV G + H G GSGQ+ KL N M+
Sbjct: 125 DTPVSGGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMI 183
Query: 182 MGITGMATAECMNMGIKMGLE 244
+GIT A AE + K G +
Sbjct: 184 VGITIGAVAEALLFATKGGAD 204
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 85.8 bits (203), Expect = 6e-16
Identities = 40/80 (50%), Positives = 52/80 (65%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM+
Sbjct: 115 DAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMV 174
Query: 182 MGITGMATAECMNMGIKMGL 241
+ + +A AE + K+GL
Sbjct: 175 LAVQQIAIAEAFVLAEKLGL 194
Score = 46.4 bits (105), Expect = 5e-04
Identities = 18/47 (38%), Positives = 28/47 (59%)
Frame = +3
Query: 240 SNRSSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELM 380
S +S DV+ ++ W+ CPVPG VPT+P++ ++ GF LM
Sbjct: 195 SAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALM 241
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 85.8 bits (203), Expect = 6e-16
Identities = 40/80 (50%), Positives = 52/80 (65%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM+
Sbjct: 115 DAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMV 174
Query: 182 MGITGMATAECMNMGIKMGL 241
+ + +A AE + K+GL
Sbjct: 175 LAVQQIAIAEAFVLAEKLGL 194
Score = 61.7 bits (143), Expect = 1e-08
Identities = 28/75 (37%), Positives = 41/75 (54%)
Frame = +3
Query: 240 SNRSSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALG 419
S +S DV+ ++ W+ CPVPG VPT+P++ ++ GF LM KDL LA
Sbjct: 195 SAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALMNKDLGLAMDAVAA 254
Query: 420 IRSPIPLGAVATQLY 464
+ PLG+ A +Y
Sbjct: 255 TGATAPLGSHAADIY 269
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 85.4 bits (202), Expect = 8e-16
Identities = 43/86 (50%), Positives = 57/86 (66%), Gaps = 3/86 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFE---RSLPILKVMGAKQFHCGQIGSGQVAKLTN 172
DAP+SGGV+GA+ TL+FM G + E R +L +MG K +H G G+G AKL N
Sbjct: 179 DAPMSGGVVGARAGTLSFMFGASSQTGELVDRVQSVLMLMGKKAWHMGNSGTGVSAKLAN 238
Query: 173 NMLMGITGMATAECMNMGIKMGLEPK 250
N L+ I +ATAE MN+GI+ GL+PK
Sbjct: 239 NYLLAINNIATAEVMNLGIRCGLDPK 264
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/84 (45%), Positives = 50/84 (59%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
D++N S+ R W E+ PVPG+V TAP+SR Y GGF LM KDL LA A +P+
Sbjct: 268 DMINTSTGRCWPMEINNPVPGVVETAPASREYAGGFGISLMNKDLRLAISAAEESGTPLA 327
Query: 438 LGAVATQLYRIVQSRGYGQKDFSL 509
L A +Y+ V+ G KDFS+
Sbjct: 328 LADKARGVYKAVEDEHRG-KDFSV 350
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 85.0 bits (201), Expect = 1e-15
Identities = 42/83 (50%), Positives = 52/83 (62%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ TL M GG + FE LP L+V G H G +G+G VAKL NN+L
Sbjct: 116 DAPVSGGPWGAEAGTLTIMCGGDRAAFEAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLL 175
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI A AE +G K G++PK
Sbjct: 176 VGIHTAAMAEAFVLGTKAGVDPK 198
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 84.6 bits (200), Expect = 1e-15
Identities = 41/80 (51%), Positives = 50/80 (62%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA TLAFM GG + ER+ PIL M K HCG G+GQ AKL NNM+
Sbjct: 115 DAPVSGGVKGATAGTLAFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAKLCNNMV 174
Query: 182 MGITGMATAECMNMGIKMGL 241
+ + +A E + K+GL
Sbjct: 175 LAVQQIAIGEAFVLAEKLGL 194
Score = 66.5 bits (155), Expect = 4e-10
Identities = 33/89 (37%), Positives = 47/89 (52%)
Frame = +3
Query: 240 SNRSSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALG 419
S +S DV+ ++ WS CPVPG VPT+P++ ++ GF LM KDL LA
Sbjct: 195 SAQSLFDVITGATGNCWSVHTNCPVPGPVPTSPANNDFKPGFATSLMNKDLGLAMAAVSS 254
Query: 420 IRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
+ PLG+ A ++Y + KDFS
Sbjct: 255 TGASAPLGSHAAEIYAKFNEE-HADKDFS 282
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 83.8 bits (198), Expect = 3e-15
Identities = 36/83 (43%), Positives = 52/83 (62%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
++ + SS + WS YCPVPG+ P P+ R Y+GGF + +M+KDL+LA A + P
Sbjct: 202 EIASKSSGQCWSITSYCPVPGVGPQTPADRGYEGGFASAMMLKDLKLAQEAAAKAGASTP 261
Query: 438 LGAVATQLYRIVQSRGYGQKDFS 506
+GA A LY + + G+G KDFS
Sbjct: 262 MGAQAEALYALFDANGFGGKDFS 284
Score = 75.8 bits (178), Expect = 7e-13
Identities = 40/94 (42%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG+M A+ TLAFM G DF L M H G G+GQ AK+ NNML
Sbjct: 116 DAPVSGGIMAAEAGTLAFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKICNNML 175
Query: 182 MGITGMATAECMNMGIKMGL-EPKFFGRAEQLIG 280
+G++ + T E + K+GL +FF A + G
Sbjct: 176 LGVSMLGTCEAFALAEKLGLAADRFFEIASKSSG 209
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 83.8 bits (198), Expect = 3e-15
Identities = 38/82 (46%), Positives = 53/82 (64%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG V A+ T+ FM G KE +E+ PILK MG F+CG+IG GQ+AK+ NM
Sbjct: 122 DAPVSGSVSEAKLGTITFMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGNMA 181
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ I ++ E + +G MG++P
Sbjct: 182 LAIQMISVCEALALGKNMGMDP 203
Score = 66.1 bits (154), Expect = 6e-10
Identities = 31/83 (37%), Positives = 51/83 (61%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
+++ SS+R W+ + Y P PG++P PS+++YDGGF ELM+KDL + + + L
Sbjct: 209 IMSVSSSRCWTVDTYNPAPGVMPNVPSNKDYDGGFMVELMLKDLGIGIEASRLSGTDTQL 268
Query: 441 GAVATQLYRIVQSRGYGQKDFSL 509
G A Q+Y + G+KDF++
Sbjct: 269 GQHAYQIYNKLNEH-LGKKDFAI 290
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 82.6 bits (195), Expect = 6e-15
Identities = 39/83 (46%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKED-FERSLPILKVMGAKQFHCGQIGSGQVAKLTNNM 178
DAPVSGGV+GA ATL+FM G F + P L +MG++ HCG+ G+G +AK+ NN+
Sbjct: 170 DAPVSGGVVGANAATLSFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNL 229
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L+GI+ + E M +G GL P
Sbjct: 230 LLGISMLGVTEAMLLGTAHGLPP 252
Score = 58.8 bits (136), Expect = 8e-08
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVP----TAPSSRNYDGGFKNELMVKDLELASGMALGIRS 428
++N S+ + WS+EV P PG + + P+ R+Y GGF LM KDL+LA A
Sbjct: 258 IINTSTGKCWSSEVNNPCPGALEGTKYSPPADRDYQGGFAARLMAKDLKLAMNTAKLQGV 317
Query: 429 PIPLGAVATQLYRIVQSRG-YGQKDFSLS 512
P PLG + + +Y + + KDF+++
Sbjct: 318 PTPLGQLTSSIYEALGGNDEFKDKDFAVA 346
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 82.2 bits (194), Expect = 8e-15
Identities = 35/81 (43%), Positives = 55/81 (67%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG GA+ A L FM GG + F+R+ P+L+ MGA+ F+ G G+GQ+AKL NN++
Sbjct: 118 DAPVAGGQAGAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKLCNNLI 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
++ +E +G K+G++
Sbjct: 178 ACVSSAVVSEAFILGSKLGMD 198
Score = 77.0 bits (181), Expect = 3e-13
Identities = 34/84 (40%), Positives = 53/84 (63%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
D++ S+ + W+ CPVPG VP++P+SR+Y GF +LM+KDL L + A + + P
Sbjct: 204 DIITQSTGQCWTLSHNCPVPGPVPSSPASRDYVPGFAADLMLKDLSLVASAASEVGAATP 263
Query: 438 LGAVATQLYRIVQSRGYGQKDFSL 509
GA A QLYR + G G +D+++
Sbjct: 264 FGARAIQLYRQLSESGLGARDWTV 287
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 81.4 bits (192), Expect = 1e-14
Identities = 38/83 (45%), Positives = 55/83 (66%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
+VLN SS R WS++ Y PVPG++ PSSR+Y+GGF ++LM KDL LA+ A + P
Sbjct: 252 EVLNTSSGRCWSSDAYNPVPGVMKGVPSSRDYNGGFASKLMAKDLNLAAASAEEVGHKSP 311
Query: 438 LGAVATQLYRIVQSRGYGQKDFS 506
L + A ++Y+ + G+ KDFS
Sbjct: 312 LISKAQEIYKKMCEEGHETKDFS 334
Score = 77.4 bits (182), Expect = 2e-13
Identities = 33/80 (41%), Positives = 52/80 (65%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV+ A+ TL FM GG ++ + + PIL+ MG +CG G+G AK+ NN+
Sbjct: 166 DAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMGRTSIYCGGSGNGSAAKICNNLA 225
Query: 182 MGITGMATAECMNMGIKMGL 241
M ++ + T+E + +G +G+
Sbjct: 226 MAVSMLGTSEALALGQSLGI 245
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 81.0 bits (191), Expect = 2e-14
Identities = 36/81 (44%), Positives = 52/81 (64%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP++GG+ GA ATL FM GG +E E + P L+ MG++ H G+ GSG KL NNM+
Sbjct: 117 DAPLTGGIEGAALATLTFMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKLVNNMI 176
Query: 182 MGITGMATAECMNMGIKMGLE 244
M +E + +G+K+GL+
Sbjct: 177 CATNLMVASEALTLGLKLGLD 197
Score = 46.0 bits (104), Expect = 6e-04
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIRSPI 434
DV+ N + SW Y P+PG+V APSSR + F M KD+ A A + +
Sbjct: 203 DVIANGTGASWVLNTYYPLPGVVDGAPSSRGFRMPTFPATGMAKDMRCALEAARSVEAVT 262
Query: 435 PLGAVATQLYRI 470
PL VA L ++
Sbjct: 263 PLHNVAESLLKL 274
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 80.2 bits (189), Expect = 3e-14
Identities = 35/83 (42%), Positives = 51/83 (61%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ TL M G + FE+ P+L V+G +H G G+G K+ NN+L
Sbjct: 121 DAPVSGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLL 180
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+G + AE + +G+K GL+P+
Sbjct: 181 LGCNMASLAEALVLGVKCGLKPE 203
Score = 38.7 bits (86), Expect = 0.096
Identities = 25/83 (30%), Positives = 43/83 (51%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
+++ SS RS++ E + S ++ GGF +L KDL LA P+P
Sbjct: 207 EIIGKSSGRSYAMEAK------MEKFIMSGDFAGGFAMDLQHKDLGLALEAGKEGNVPLP 260
Query: 438 LGAVATQLYRIVQSRGYGQKDFS 506
+ A+ATQ++ ++ G G++D S
Sbjct: 261 MTAMATQIFEGGRAMGLGREDMS 283
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 80.2 bits (189), Expect = 3e-14
Identities = 39/88 (44%), Positives = 56/88 (63%), Gaps = 3/88 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKED---FERSLPILKVMGAKQFHCGQIGSGQVAKLTN 172
DAPVSGGV+GA+ TL FM G K+ +++ +LK+MG + +CG G G AKL N
Sbjct: 151 DAPVSGGVVGAEKGTLTFMVGCNKDKQQVYKQVEELLKLMGGRIVNCGTQGQGLAAKLAN 210
Query: 173 NMLMGITGMATAECMNMGIKMGLEPKFF 256
N L+ +T +ATAE ++ K+G + K F
Sbjct: 211 NYLLAVTNVATAEAFHLAEKLGCDLKLF 238
Score = 67.7 bits (158), Expect = 2e-10
Identities = 38/85 (44%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
D++N+SS RSWS+EV PVPG+ P PSSR+Y GGF LM KDL LA +A S +
Sbjct: 240 DIVNSSSGRSWSSEVNNPVPGVNPATPSSRDYVGGFGINLMRKDLGLAIDVAKQSGSSML 299
Query: 438 LGAVATQLYR-IVQSRGYGQKDFSL 509
+ ++Y+ I + Y KD S+
Sbjct: 300 VADKTYEVYQNIEKGDNYQGKDMSV 324
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 79.8 bits (188), Expect = 4e-14
Identities = 44/84 (52%), Positives = 52/84 (61%), Gaps = 3/84 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGR-KEDFERSLPILKVMGAKQ--FHCGQIGSGQVAKLTN 172
DAPVSGG MGAQ+ TLAFMAG K F R L MG F CG IG+G K+ N
Sbjct: 141 DAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGYLSHMGKPDAIFLCGDIGAGTAFKVIN 200
Query: 173 NMLMGITGMATAECMNMGIKMGLE 244
N L IT +A +E +N+G KMGL+
Sbjct: 201 NYLSAITSLAASEALNIGTKMGLD 224
Score = 50.0 bits (114), Expect = 4e-05
Identities = 24/52 (46%), Positives = 32/52 (61%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMA 413
DV+N S + W T PVPG+ PSSR+Y+GGF+ EL K L + S +A
Sbjct: 230 DVINVSGGQCWVTSKSNPVPGVQANVPSSRDYEGGFRIELCRKVLGMGSELA 281
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 79.4 bits (187), Expect = 6e-14
Identities = 35/83 (42%), Positives = 54/83 (65%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
++N +S R WS+EVY P PG++ P+S+ Y+GGF ELM+KDL LA+ A + +PL
Sbjct: 222 IMNTASGRCWSSEVYNPCPGVLENVPASKGYEGGFACELMLKDLGLAADAAKQASADVPL 281
Query: 441 GAVATQLYRIVQSRGYGQKDFSL 509
G A +Y+ + G +KDF++
Sbjct: 282 GNHAKDIYQKLVELGLNRKDFAI 304
Score = 75.8 bits (178), Expect = 7e-13
Identities = 38/84 (45%), Positives = 54/84 (64%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGR-KEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNM 178
DAPVSGGV A TL FM G KE F+ +L+ MG +C + G+G +AK+ NNM
Sbjct: 134 DAPVSGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICNNM 193
Query: 179 LMGITGMATAECMNMGIKMGLEPK 250
+GI +A AE +++G K+G++PK
Sbjct: 194 ALGIEMIAVAEAISLGKKLGIDPK 217
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 79.0 bits (186), Expect = 7e-14
Identities = 35/80 (43%), Positives = 49/80 (61%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG++GA+ TL M GG D E P+++ MG + FHCG +GS ++AK+ NNML
Sbjct: 122 DAPVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKVINNML 181
Query: 182 MGITGMATAECMNMGIKMGL 241
TAE + + G+
Sbjct: 182 CVANMFLTAEAIELAESHGV 201
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 78.6 bits (185), Expect = 1e-13
Identities = 39/82 (47%), Positives = 47/82 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG MGA+ TL M GG + FERS +L G H G IGSG V KL NNM+
Sbjct: 119 DAPVSGGPMGAKAGTLTIMCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMV 178
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+G+ EC K G++P
Sbjct: 179 IGVHQAVLGECYLFVEKAGVDP 200
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 78.6 bits (185), Expect = 1e-13
Identities = 36/80 (45%), Positives = 46/80 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA TL M G E F + PI V+G +H G+ G G K+ NN+L
Sbjct: 122 DAPVSGGVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLL 181
Query: 182 MGITGMATAECMNMGIKMGL 241
+G A AE + +G+K GL
Sbjct: 182 LGCNMAALAEALTLGVKCGL 201
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/52 (36%), Positives = 33/52 (63%)
Frame = +3
Query: 351 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
++GGF +L KDL LA + + P+P+ A A Q+Y + +++G G++D S
Sbjct: 233 FNGGFAVDLQYKDLGLALEASRDEKVPLPMTAAAVQVYEMARAKGQGREDMS 284
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 78.6 bits (185), Expect = 1e-13
Identities = 40/83 (48%), Positives = 49/83 (59%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GAQN TLA M GG KE FE +PI +MG + G GSGQ K+ N +
Sbjct: 119 DAPVSGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIA 178
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ + AE M K GLEP+
Sbjct: 179 IAAGMIGVAEAMAYAQKSGLEPE 201
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 77.4 bits (182), Expect = 2e-13
Identities = 38/82 (46%), Positives = 50/82 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA + LA GG +E ++R LP L+ M + + G IG+G +AKL NNM
Sbjct: 117 DAPVSGGPAGAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAKLVNNMA 176
Query: 182 MGITGMATAECMNMGIKMGLEP 247
AE ++MG+K GLEP
Sbjct: 177 STAIISVLAEALSMGVKAGLEP 198
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 75.8 bits (178), Expect = 7e-13
Identities = 38/82 (46%), Positives = 48/82 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG MGAQ ATL+ M GG+ E ER P+L+++G H G G+GQVAK N ++
Sbjct: 122 DAPVSGGTMGAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKACNQIV 181
Query: 182 MGITGMATAECMNMGIKMGLEP 247
I AE M G +P
Sbjct: 182 QVINIQGIAEAMLFARAQGTDP 203
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 75.8 bits (178), Expect = 7e-13
Identities = 36/83 (43%), Positives = 51/83 (61%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG V A+ L +AGGRKE+ + P+ +V+G H G+ G G AKL+ N+L
Sbjct: 122 DAPVSGSVQPAKEGNLVILAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLL 181
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+G+T +E + G K+GLE K
Sbjct: 182 LGLTIEGASEAILFGEKLGLEKK 204
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 75.8 bits (178), Expect = 7e-13
Identities = 34/81 (41%), Positives = 49/81 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA++ TLA M G ++DF+R LP+ MG G +GSG +AK N ++
Sbjct: 136 DAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQLI 195
Query: 182 MGITGMATAECMNMGIKMGLE 244
+G T A AE + + G++
Sbjct: 196 VGTTTAALAEAAELAERSGMD 216
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 74.5 bits (175), Expect = 2e-12
Identities = 33/83 (39%), Positives = 51/83 (61%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA +++ + G D R++P+L+ M + H GQ G+G VAK+ NNML
Sbjct: 119 DAPVSGGPKGAATGSMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVAKIANNML 178
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
++TAE + M + G++P+
Sbjct: 179 AACHLISTAEAVAMAARAGVDPE 201
Score = 42.3 bits (95), Expect = 0.008
Identities = 29/83 (34%), Positives = 41/83 (49%)
Frame = +3
Query: 255 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 434
L LN S RS +T+V + PT ++ YD GF LM KD+ LAS +A + +
Sbjct: 204 LQGLNAGSGRSGATQV------MFPTWVLNKAYDSGFTMGLMRKDVGLASDLADSLDMDL 257
Query: 435 PLGAVATQLYRIVQSRGYGQKDF 503
PL V QL++ +DF
Sbjct: 258 PLSRVVAQLWQASSETLADNEDF 280
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 74.5 bits (175), Expect = 2e-12
Identities = 39/100 (39%), Positives = 60/100 (60%), Gaps = 2/100 (2%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D+PVSGG A + TLAFMAGG++E +++ P +MG+ G GSG V KLTN ++
Sbjct: 116 DSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKLTNQVI 175
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQ--LIGSLLVD 295
+ +T A +E + K G +P+ +A + L GS ++D
Sbjct: 176 VNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTILD 215
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 73.3 bits (172), Expect = 4e-12
Identities = 33/88 (37%), Positives = 49/88 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ +LA M GG D ER P+L +G + H G +G+GQV K N M+
Sbjct: 123 DAPVSGGTPGAEAGSLAIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMI 182
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRA 265
+ + AE + + + G++ + A
Sbjct: 183 VACNALVIAEVVALAERSGVDARLIAEA 210
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 72.9 bits (171), Expect = 5e-12
Identities = 35/82 (42%), Positives = 53/82 (64%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+ A+LA M GG +E F++ +LK++G G + SGQ++KL N ++
Sbjct: 117 DAPVSGGTIGAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQII 175
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+G+T A AE + + K G P
Sbjct: 176 VGVTIGAVAEAVTLCEKSGTNP 197
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 72.9 bits (171), Expect = 5e-12
Identities = 38/86 (44%), Positives = 50/86 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG A+ TL M GG++E FE P L+ K + GQ GSGQ+ KL N +L
Sbjct: 116 DAPVSGMESRAKEGTLTTMCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKLINQLL 175
Query: 182 MGITGMATAECMNMGIKMGLEPKFFG 259
I A AE + M +K+GL+P+ G
Sbjct: 176 FDINVAALAEILPMSVKLGLDPEKVG 201
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 72.5 bits (170), Expect = 6e-12
Identities = 34/81 (41%), Positives = 45/81 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ TLA MAGG D ER P + M + H G G+GQ AKL N ++
Sbjct: 141 DAPVSGGTKGAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKLCNQVI 200
Query: 182 MGITGMATAECMNMGIKMGLE 244
+G AE + + G++
Sbjct: 201 VGCAMAVLAEATRLAVNAGID 221
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 72.5 bits (170), Expect = 6e-12
Identities = 34/81 (41%), Positives = 46/81 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA++ TLA M GGR E E+ P+L MG++ H G G+GQ K N ++
Sbjct: 115 DAPVSGGVEGARDGTLALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKAVNQVM 174
Query: 182 MGITGMATAECMNMGIKMGLE 244
A E + G + L+
Sbjct: 175 CAGINQAVTEALAFGQALDLD 195
Score = 36.7 bits (81), Expect = 0.39
Identities = 19/53 (35%), Positives = 27/53 (50%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
++ GFK L KDL + MA + P+PL + Y + +RGYG D S
Sbjct: 224 SFQPGFKLSLHHKDLNICLEMAERLGIPLPLSTRSRDDYAELMARGYGDDDIS 276
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 72.5 bits (170), Expect = 6e-12
Identities = 36/82 (43%), Positives = 49/82 (59%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA TLA M GG D ER+ PIL+ +G + H G G+G K+ N ++
Sbjct: 111 DAPVSGGPEGAAAGTLAIMVGGTASDVERAEPILRALG-RPTHVGPPGAGHTVKVINQLI 169
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+G+T A AE M + G++P
Sbjct: 170 VGLTIQAVAEAMVLAEAYGIDP 191
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 72.5 bits (170), Expect = 6e-12
Identities = 34/82 (41%), Positives = 45/82 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA + L + GG ER P+L+ M A+ H G GSG V KL NN L
Sbjct: 125 DAPVSGGPAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYL 184
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ TAE + + + G++P
Sbjct: 185 CAAHLLTTAEAVTLAARAGVDP 206
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 72.1 bits (169), Expect = 8e-12
Identities = 38/82 (46%), Positives = 48/82 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGGV GA+ TLA M G K +FE P L V+G F + G+ Q KL NN L
Sbjct: 170 DCPVSGGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQTMKLANNFL 229
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+AT+E + MG+K GL+P
Sbjct: 230 SATAIVATSEAVVMGVKAGLDP 251
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 72.1 bits (169), Expect = 8e-12
Identities = 33/81 (40%), Positives = 51/81 (62%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGGV GA+ TLA +AGG +R P+L ++ A+ G +G+GQ AKL N ++
Sbjct: 120 DCPVSGGVAGAEAGTLAILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLI 179
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ +A AE M++G +G++
Sbjct: 180 VATNMLAIAEAMHVGEALGID 200
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 72.1 bits (169), Expect = 8e-12
Identities = 37/85 (43%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSL--PILKVMGAKQFHCGQIGSGQVAKLTNN 175
DAPVSGGV+GAQ +AF G K D L L++MG + CG G AKL NN
Sbjct: 132 DAPVSGGVLGAQKGAIAFFLGCAKTDPNLPLLTDTLRLMGKEVIPCGGPSLGLSAKLCNN 191
Query: 176 MLMGITGMATAECMNMGIKMGLEPK 250
L G+ +A +E +N+G++ GL+P+
Sbjct: 192 YLSGLIAIANSEALNIGMRAGLDPR 216
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 6/79 (7%)
Frame = +3
Query: 246 RSSLD--VLNNSSARSWSTEVYC----PVPGLVPTAPSSRNYDGGFKNELMVKDLELASG 407
R+ LD VL++ A + C P PG+VP APSS++Y GFK +LM KD LA
Sbjct: 210 RAGLDPRVLSSVFAAGTAQNAICDRFNPCPGVVPDAPSSKDYRTGFKIQLMRKDFALAVA 269
Query: 408 MALGIRSPIPLGAVATQLY 464
MA + + + LG + Y
Sbjct: 270 MAEQVGARLVLGEAGLKTY 288
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 71.7 bits (168), Expect = 1e-11
Identities = 36/83 (43%), Positives = 48/83 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV A +L MAGG +D +++ PIL MG + F G IGSG K NN +
Sbjct: 122 DAPVSGGVKRAVEGSLTIMAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAMKAINNFV 181
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
G +A E + +G GL+P+
Sbjct: 182 SGAGVLAAIEGVLLGRTFGLDPR 204
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 71.7 bits (168), Expect = 1e-11
Identities = 36/81 (44%), Positives = 48/81 (59%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA TLA MAGG D E P+L ++ H G +G+GQ AKL N +
Sbjct: 179 DAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLCNQTI 238
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T A AE +++ + GL+
Sbjct: 239 VTATLAAIAEAVSLAQRSGLD 259
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/81 (43%), Positives = 51/81 (62%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQ-IGSGQVAKLTNNM 178
DAPVSG + A T++ +A G K+ FE++LP+L+ + FHCG+ +G+GQ K NNM
Sbjct: 116 DAPVSGAMATAIAGTISIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMKTVNNM 175
Query: 179 LMGITGMATAECMNMGIKMGL 241
+ +AT E + MG K GL
Sbjct: 176 MNVSCRLATLEVVAMGRKFGL 196
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 71.3 bits (167), Expect = 1e-11
Identities = 34/81 (41%), Positives = 48/81 (59%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ TL M GG + +ER P+L V+G + G+ G+G AK+ N L
Sbjct: 118 DAPVSGGPEGAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYL 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ + +A AE M G+ GL+
Sbjct: 178 VAVHSVAAAEAMVAGVAYGLD 198
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 71.3 bits (167), Expect = 1e-11
Identities = 36/81 (44%), Positives = 51/81 (62%), Gaps = 1/81 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGS-GQVAKLTNNML 181
APVSGGV+GA NATL M GG K+D++ + I ++G +H G S G KL NN++
Sbjct: 139 APVSGGVIGAVNATLTIMVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLM 198
Query: 182 MGITGMATAECMNMGIKMGLE 244
+G A AE + +G KMG++
Sbjct: 199 IGFYTEAVAETIVLGEKMGID 219
Score = 45.6 bits (103), Expect = 8e-04
Identities = 21/55 (38%), Positives = 31/55 (56%)
Frame = +3
Query: 342 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
+ NY GF L++KDL+LA GMA + +G +LY + +GYG+ D S
Sbjct: 247 NNNYAPGFSTNLLLKDLKLAKGMADEAGVSLRIGEKLVELYSEIAQQGYGENDMS 301
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/81 (43%), Positives = 47/81 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GAQ TLA MAGGR D + P++ ++ H G G+GQ AKL N +
Sbjct: 110 DAPVSGGVPGAQAGTLAVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQAI 169
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T A AE + + G++
Sbjct: 170 VTATVTAIAEAVGLAQASGID 190
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/81 (43%), Positives = 45/81 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A+ LA M GG FER +L+V+G + G GSG V KL NN+
Sbjct: 121 DAPVSGGPARAKTGELAIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLA 180
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ I MA E + G+ G+E
Sbjct: 181 ISIIAMANIEALAFGVANGVE 201
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 70.9 bits (166), Expect = 2e-11
Identities = 36/83 (43%), Positives = 48/83 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A + TLA M GG+ E FER P+L MGA G +G+G V KL N ++
Sbjct: 118 DAPVSGGEPKAIDGTLAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTKLANQIM 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ A E + + K GL+P+
Sbjct: 178 VACNIAAMGEALVLATKAGLDPE 200
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 70.5 bits (165), Expect = 3e-11
Identities = 34/74 (45%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNML 181
APVSGGV+GA+N TL M GG++E F++ IL V+G FH G QI G KL NN+L
Sbjct: 119 APVSGGVVGAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLL 178
Query: 182 MGITGMATAECMNM 223
+G +E + +
Sbjct: 179 IGFYTAGVSEALQI 192
Score = 38.3 bits (85), Expect = 0.13
Identities = 18/58 (31%), Positives = 33/58 (56%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSLSSSY 521
+++ GF +L+ KDLE A +A + +P+ LYR ++ +GYG +D ++ Y
Sbjct: 229 DFNPGFALKLLRKDLEFAMEVADNNQLDLPISKSLLDLYRNLEHQGYGDQDMAVLYKY 286
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 70.5 bits (165), Expect = 3e-11
Identities = 31/81 (38%), Positives = 49/81 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG GA+ TL M GG+++ F+R PI K MG H G +GSGQ KL N ++
Sbjct: 117 DAPVTGGDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVV 176
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ + ++ E + + +G++
Sbjct: 177 VALNMVSVVEGLLLARSLGID 197
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 70.1 bits (164), Expect = 3e-11
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG +GA N TL+ M GG E F++ ILK++G K + G G GQ AKL N +L
Sbjct: 116 DAPVTGGDIGALNGTLSIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAKLFNQIL 175
Query: 182 MGITGMATAECMN 220
+ + ATAE +N
Sbjct: 176 VAVNTFATAEVLN 188
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/83 (43%), Positives = 47/83 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA + L+ M GG + E + P L+ M AK H G G+G VAKL NNML
Sbjct: 125 DAPVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNML 184
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ + T E + +G G+ K
Sbjct: 185 VANHMVTTLEALRLGEAAGVAAK 207
Score = 39.5 bits (88), Expect = 0.055
Identities = 27/86 (31%), Positives = 44/86 (51%)
Frame = +3
Query: 246 RSSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIR 425
+ L+V+N+++ RS +EV+ P ++P R++D GF LM KDL LA +A +
Sbjct: 207 KEMLEVVNSATGRSAISEVHYP-NWVLP-----RSFDSGFSAGLMRKDLRLARALAAEVS 260
Query: 426 SPIPLGAVATQLYRIVQSRGYGQKDF 503
P+ +L+ QS DF
Sbjct: 261 VATPMADRVAELWAETQSGLSDSDDF 286
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/82 (43%), Positives = 48/82 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG AQNA L ++ GG R+ P+L +MG K H G++GSG +AKL N L
Sbjct: 119 EAPVSGSRPQAQNAELVYLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALAKLVTNTL 178
Query: 182 MGITGMATAECMNMGIKMGLEP 247
MGI AE + M + G +P
Sbjct: 179 MGIQVTTIAELIGMLKRQGQDP 200
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 69.7 bits (163), Expect = 4e-11
Identities = 32/83 (38%), Positives = 45/83 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV A+ TLA + GG + R P+L MG H G G+G AK NN +
Sbjct: 123 DAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNNYV 182
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ AT E + + + G++P+
Sbjct: 183 SAASVAATVEALQIASRFGIDPQ 205
Score = 32.3 bits (70), Expect = 8.3
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
DVLN S+ RS ++E S + GF +LM KDL++A +A + P+
Sbjct: 209 DVLNASTGRSNTSE------NKAKQFMLSGTFASGFALQLMNKDLKIARALAQAVGHPMT 262
Query: 438 LGAVATQLY 464
GA +++
Sbjct: 263 FGATCVEVW 271
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 69.7 bits (163), Expect = 4e-11
Identities = 36/85 (42%), Positives = 49/85 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+N TLA MAGG + R P+ +G + G IG+GQ+AKL N ++
Sbjct: 116 DAPVSGGEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQLI 174
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+G+T A +E + G P F
Sbjct: 175 VGVTIGAVSEAFVLAEAGGASPARF 199
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 69.7 bits (163), Expect = 4e-11
Identities = 34/83 (40%), Positives = 47/83 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA TL FM GG + R+ P+ + MG K G +GQ K+ N M+
Sbjct: 121 DAPVSGGVGGAAAGTLTFMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKMCNQMI 180
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ +A AE ++ K+G+ PK
Sbjct: 181 YASSLVAVAEAFSLADKLGVAPK 203
Score = 40.3 bits (90), Expect = 0.031
Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSS-RNYDGGFKNELMVKDLELASGMALGIRSPI 434
+V+ +SS W+ CP P +V ++ + F + LM KDL LA+ A + P+
Sbjct: 207 EVVTSSSGDCWAIRNSCPWPDVVEGGSAADEGFAPRFSSRLMSKDLRLATSAASNVGQPL 266
Query: 435 PLGAVATQLYRIV 473
PL Y V
Sbjct: 267 PLTGKTVTFYEKV 279
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 69.3 bits (162), Expect = 6e-11
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+G GA++ L FM GG + F + P+L MG K + CG G G AKLT N++
Sbjct: 119 DAPVTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLV 178
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ MA E M + K G++PK
Sbjct: 179 LSNILMAFNEGMVLATKGGMDPK 201
Score = 33.5 bits (73), Expect = 3.6
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKD--LELASGMALGIRS 428
L++L+NS+A+S P SRN+ F + M KD L L SG LG+
Sbjct: 204 LEILDNSAAKSGLISYKAPFV-------FSRNFTTNFSVKWMHKDIGLMLESGKDLGV-- 254
Query: 429 PIPLGAVATQLYRIVQSRGYGQKD 500
P+ L + QL++ + G+G +D
Sbjct: 255 PLYLTGLTRQLFQTAIAAGHGDED 278
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 69.3 bits (162), Expect = 6e-11
Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A + TL+ M GG K F++ ++K M H G+IG+G V KL N ++
Sbjct: 117 DAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVI 176
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQ--LIGSLLVD 295
+ + A +E + + K G+ P +A + L GS ++D
Sbjct: 177 VALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD 216
Score = 38.3 bits (85), Expect = 0.13
Identities = 18/59 (30%), Positives = 33/59 (55%)
Frame = +3
Query: 345 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSLSSSY 521
RN+ GF+ +L +KDL A + G+ + +PL A ++ + +++ G G D S + Y
Sbjct: 225 RNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALACY 283
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 68.9 bits (161), Expect = 8e-11
Identities = 35/81 (43%), Positives = 49/81 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+NA L+ M GG +E + PIL+ MG + G GSGQ AK+ N ++
Sbjct: 130 DAPVSGGDVGARNAALSIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIV 189
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T + E + G K GL+
Sbjct: 190 ITGTMIGVCESLMYGFKAGLD 210
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/81 (41%), Positives = 47/81 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+G V GA+N + AGG KE ER P++++MG + G GSG + KL +N L
Sbjct: 117 DAPVTGAVDGARNGNMTQFAGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQL 175
Query: 182 MGITGMATAECMNMGIKMGLE 244
I A E + M +K G+E
Sbjct: 176 WAIHATAMGEALVMAVKSGVE 196
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 68.5 bits (160), Expect = 1e-10
Identities = 36/81 (44%), Positives = 45/81 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG GA+ ATL+ MAGG F R P+LK +G H G G+GQ K N M
Sbjct: 125 DCPVSGGAAGARAATLSMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIKAANQMA 184
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ I + AE MN ++ G E
Sbjct: 185 LCIQLVGIAEAMNYALEQGAE 205
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 68.5 bits (160), Expect = 1e-10
Identities = 33/72 (45%), Positives = 43/72 (59%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA TL+ M GG FER+LP+ + MG H G IG+GQ KL N +L
Sbjct: 121 DAPVSGGSEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQIL 180
Query: 182 MGITGMATAECM 217
+ +A +E +
Sbjct: 181 VVGHALAMSEAL 192
Score = 36.7 bits (81), Expect = 0.39
Identities = 20/51 (39%), Positives = 29/51 (56%)
Frame = +3
Query: 345 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQK 497
R++ GF +L KDL L A + P+P A+ QLYR +Q+RG G +
Sbjct: 229 RDWRPGFTIDLQQKDLRLVLQEADRLGVPLPGTALIHQLYRTLQARGLGHE 279
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 68.1 bits (159), Expect = 1e-10
Identities = 33/83 (39%), Positives = 50/83 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GGVMGA+ L F+ GG E + P+ +MG K H G GSG K+ NNM
Sbjct: 119 DAPVTGGVMGARIGKLNFLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKICNNMS 178
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI+ +A +E + + ++ ++ K
Sbjct: 179 LGISMIAASESLMLAKRLKMDIK 201
Score = 53.6 bits (123), Expect = 3e-06
Identities = 25/83 (30%), Positives = 40/83 (48%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
+++ +S +W+ Y P+P L PS+ Y GF +M KDL LA A + + P
Sbjct: 205 EIIKAASGNNWAMTNYTPLPNLTDGVPSNNKYRPGFTASMMRKDLRLAMDAAQSVDASTP 264
Query: 438 LGAVATQLYRIVQSRGYGQKDFS 506
LG A +++ G D+S
Sbjct: 265 LGKAALEIFSKFCDEGDSDTDYS 287
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/82 (43%), Positives = 49/82 (59%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV+GA+ +LA MAGG +DF + +L VMG G G GQ+AKL N ++
Sbjct: 121 DAPVSGGVVGAEAGSLAIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLI 179
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+G T AE + + G +P
Sbjct: 180 VGGTLNIVAEALLLAQAGGADP 201
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 68.1 bits (159), Expect = 1e-10
Identities = 32/81 (39%), Positives = 44/81 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG GA AT+ + GG E P+L + AKQ H G G+G V KL NN+L
Sbjct: 118 DGPVSGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLL 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
G+ + T+E + G++
Sbjct: 178 TGVHLLVTSEAVRAAEAAGVD 198
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 67.7 bits (158), Expect = 2e-10
Identities = 34/81 (41%), Positives = 44/81 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA L+ M GG E ER+ P+L GA G +GSGQ+ K+ N +L
Sbjct: 118 DAPVSGGEAGAMAGRLSIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKMVNQIL 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ AE +N I GL+
Sbjct: 178 VAGAVEGAAEAINFAIAAGLD 198
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/102 (32%), Positives = 54/102 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A+ L + GG++ D ER+ ++ + A H G +G+GQ AK N +
Sbjct: 113 DAPVSGGPQLAETGELTMLLGGQERDIERARAVIDALAANATHLGPLGAGQAAKTLNQAI 172
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGVL 307
+G+ + AE + + K G++P R Q + + D +L
Sbjct: 173 VGVNYVLMAELLALARKSGIDP---ARLPQALAGGMADSQIL 211
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 67.7 bits (158), Expect = 2e-10
Identities = 31/81 (38%), Positives = 46/81 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA+ TLA M GG + ++ +P+++ FH G GSGQ KL NN +
Sbjct: 116 DAPVSGGVQGAEAGTLAVMLGGDEASVKKVIPLIETYAGNIFHVGPSGSGQAIKLANNQI 175
Query: 182 MGITGMATAECMNMGIKMGLE 244
+A E ++ + G++
Sbjct: 176 TAANIVALGEGLSSAVAAGVD 196
Score = 33.5 bits (73), Expect = 3.6
Identities = 27/86 (31%), Positives = 38/86 (44%)
Frame = +3
Query: 249 SSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 428
+++ VL SSA S Y P P+ GF + M KDL L A +
Sbjct: 199 TAVAVLTKSSANSNVLSNYFPKTLFTEERPT------GFALDFMHKDLGLFLNAAGKAKL 252
Query: 429 PIPLGAVATQLYRIVQSRGYGQKDFS 506
P P+ ++ L+ I Q G G KDF+
Sbjct: 253 PTPVTSLVRDLFSIGQRDGRGGKDFT 278
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 67.3 bits (157), Expect = 2e-10
Identities = 33/81 (40%), Positives = 45/81 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG GA+N TL MAGG + ER P+L+ M + G +G G+ K N ML
Sbjct: 103 DGPVSGGTAGAENGTLTVMAGGDADVLERLRPVLESMATNIYLVGSVGDGKAIKAINQML 162
Query: 182 MGITGMATAECMNMGIKMGLE 244
GI A AE + + K+ ++
Sbjct: 163 AGIHMAAAAEAVALAEKLEID 183
Score = 33.1 bits (72), Expect = 4.8
Identities = 26/82 (31%), Positives = 39/82 (47%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
V+ +SS SW E + GL+ R++ GFK LM KD+++A G +PL
Sbjct: 190 VVGSSSGNSWMLEN--KMDGLI-----RRDFTPGFKLNLMKKDIQIAVNEGNG--KQLPL 240
Query: 441 GAVATQLYRIVQSRGYGQKDFS 506
L++ + G KDFS
Sbjct: 241 ANYVLDLFK-QSEKDAGDKDFS 261
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 67.3 bits (157), Expect = 2e-10
Identities = 32/61 (52%), Positives = 38/61 (62%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA NA L+ M GG EDFE + PIL V+G H G GSGQ K N ++
Sbjct: 118 DAPVSGGEAGAVNAALSIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVKAANQLI 177
Query: 182 M 184
+
Sbjct: 178 V 178
Score = 33.5 bits (73), Expect = 3.6
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = +3
Query: 345 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
R+++ GF+ +L KDL + + A PLGAV QL ++ G G D S
Sbjct: 226 RSFEPGFRIDLHHKDLGIVTSAAREAGVVTPLGAVLAQLMASARANGDGGLDHS 279
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 67.3 bits (157), Expect = 2e-10
Identities = 35/88 (39%), Positives = 45/88 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV GGV+ A++A+L M G ER P+ MG K + CG IGS V K N +
Sbjct: 121 DAPVMGGVVFAKDASLDIMVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKAMTNYI 180
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRA 265
+ T E M +G K GL+ K A
Sbjct: 181 NACALINTLEAMTIGRKFGLDSKVMAEA 208
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 66.9 bits (156), Expect = 3e-10
Identities = 35/83 (42%), Positives = 47/83 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA + TLA M GG FER P+ +G + H G GSGQ+AKL N +
Sbjct: 140 DAPVSGGERGAIDGTLAIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQLAKLANQSI 198
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ T AE + + + G +P+
Sbjct: 199 VANTIATVAEALLLAERGGADPR 221
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 66.9 bits (156), Expect = 3e-10
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG GA+ TL + GG D +R++P+L+ +G H G +GSGQ K N +L
Sbjct: 132 DAPVTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVKAVNQVL 191
Query: 182 MGITGMATAECMNMG 226
+ + A AE + +G
Sbjct: 192 VAGSYAAVAEAIALG 206
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 66.9 bits (156), Expect = 3e-10
Identities = 31/82 (37%), Positives = 50/82 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG A++ L F+ G K +E++ P L +MG +F+ G++G+G KL NM+
Sbjct: 212 EAPVSGSKKPAEDGQLIFLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKLVVNMI 271
Query: 182 MGITGMATAECMNMGIKMGLEP 247
MG + AE + + K+GL+P
Sbjct: 272 MGSMMASFAEGILLSQKVGLDP 293
Score = 40.3 bits (90), Expect = 0.031
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +3
Query: 351 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
Y F + KD+ LA G+A + P+ A A +LY++ +S G +DFS
Sbjct: 322 YPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFS 373
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 66.9 bits (156), Expect = 3e-10
Identities = 39/87 (44%), Positives = 50/87 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA TL FM G ++D P L+++ F CG G AKL NN
Sbjct: 142 DAPVSGGSLGAVAGTLTFMVGCVEDD-----PNLELL---IFPCGGFLLGLTAKLCNNYC 193
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGR 262
G+ +ATAE MN+GIK G++P R
Sbjct: 194 SGLIAIATAEAMNIGIKSGMKPSLLAR 220
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 66.1 bits (154), Expect = 6e-10
Identities = 33/81 (40%), Positives = 46/81 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA +L+ MAGG F ++ P + MG H G G+GQVAK N ++
Sbjct: 114 DAPVSGGEVGAIAGSLSIMAGGSDAAFAKAKPAFECMGKNIVHVGASGAGQVAKAANQIV 173
Query: 182 MGITGMATAECMNMGIKMGLE 244
G+ +A AE K G++
Sbjct: 174 TGMGVLAVAEAFAFAAKNGVD 194
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 66.1 bits (154), Expect = 6e-10
Identities = 31/70 (44%), Positives = 42/70 (60%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA L+ M GG E F ++ P+L+ MG H G +G GQV K+ N ++
Sbjct: 118 DAPVSGGVRGAIAGELSIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFKMCNQLM 177
Query: 182 MGITGMATAE 211
+G+ A E
Sbjct: 178 VGVHIQAMCE 187
Score = 33.9 bits (74), Expect = 2.7
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +3
Query: 342 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYG 491
+++ GF+ +L +KDL LA A P+P A+AT LY ++ G G
Sbjct: 225 AKDDSAGFRIDLQLKDLRLAGEAAFEKGLPLPGLAMATSLYLEARAHGEG 274
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 65.7 bits (153), Expect = 7e-10
Identities = 33/85 (38%), Positives = 48/85 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG +GA+N TLA + GG + F+ P+ + MG G G GQ AKL N +
Sbjct: 119 DAPVTGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIA 178
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+ + + TAE + K G++P F
Sbjct: 179 IAGSMIGTAEMLLFVTKSGIDPTQF 203
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/82 (39%), Positives = 47/82 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV A+ L+ M GG +D R+ +L++MG H G IG+GQ K NN++
Sbjct: 117 DAPVSGGVARAKTGDLSIMTGGSADDCARAETLLRLMGTTITHVGDIGAGQAMKALNNLV 176
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ E + +G + GL+P
Sbjct: 177 SAGGFLIGVEALLIGQRFGLDP 198
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/83 (38%), Positives = 45/83 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG+ GA LA GG D R+ P+L +G H G GSGQVAK N ++
Sbjct: 118 DAPVSGGLAGAAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKACNQVI 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
++ A AE + + + + P+
Sbjct: 178 GFLSFAALAEALALAARYDIAPR 200
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 65.7 bits (153), Expect = 7e-10
Identities = 37/90 (41%), Positives = 50/90 (55%), Gaps = 3/90 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGG-RKEDFERSL-PILKVMGAKQFHCGQI-GSGQVAKLTN 172
D PVSGGV GA+ ATL+FM E L +L MGA F CG+ G+G AKL+N
Sbjct: 158 DTPVSGGVAGARKATLSFMLSRPNNESISADLRTLLNKMGANIFACGETHGAGLAAKLSN 217
Query: 173 NMLMGITGMATAECMNMGIKMGLEPKFFGR 262
N L+ +T +A A+ + GL K + +
Sbjct: 218 NYLLAVTNLAVADSFQLAKSFGLNLKDYAK 247
Score = 40.7 bits (91), Expect = 0.024
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Frame = +3
Query: 273 SSARSWSTEVYCPVPGLVP---TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 443
S+ + W+ CP+PG P P+ Y+GGF ++L KDL LA+ A + LG
Sbjct: 252 STGKCWAAVDNCPIPGAYPKENNLPADVKYEGGFISKLTRKDLVLATQSAEYANRFLYLG 311
Query: 444 AVATQLY-RIVQSRGYGQKDFSL 509
V+ Y + + +D S+
Sbjct: 312 DVSKHWYDKACEREDLANRDLSV 334
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 64.9 bits (151), Expect = 1e-09
Identities = 35/85 (41%), Positives = 45/85 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG V A TLA MAG + D R PIL+ MGA H G +GS K NN +
Sbjct: 127 DAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMKALNNYV 186
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+A +E M + +M L+ + F
Sbjct: 187 YAAGLLAVSEAMVIARRMELDLEVF 211
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 64.9 bits (151), Expect = 1e-09
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQ-IGSGQVAKLTNNML 181
APVSGG + A+ TL MA G E FE P L+V+G F+ G G GQ K+ NN L
Sbjct: 117 APVSGGTVAAEKGTLTVMAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTL 176
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ +A+ E + G+K GL+
Sbjct: 177 CAVGMVASCEALVFGVKAGLD 197
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 64.9 bits (151), Expect = 1e-09
Identities = 33/80 (41%), Positives = 43/80 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG + AQ TL +AGG + P+L MG K +CG GSG KL N+L
Sbjct: 119 DAPVSGSKVPAQTGTLVILAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKLAINLL 178
Query: 182 MGITGMATAECMNMGIKMGL 241
+GI AE +++ GL
Sbjct: 179 LGIMTEGIAEALHLAESSGL 198
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 64.9 bits (151), Expect = 1e-09
Identities = 51/158 (32%), Positives = 73/158 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+ TL M GG++ F+ P+ +MG G G+GQV K+ N ++
Sbjct: 119 DAPVSGGQVGAKGGTLTIMVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQII 178
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGVLSSPRTGAHRSVE*KLRWR 361
+ + A AE + K G +P E L+G G SS H R
Sbjct: 179 VALNIEAVAEALLFASKAGADPARV--REALMG------GFASSKILEVHAE-------R 223
Query: 362 LQKRTYG*GLRISQWHGVGYSFADPIGRCRNSALPHRA 475
+ KRT+ G RI + H + A R +LP+ A
Sbjct: 224 MIKRTFDPGFRI-ELHQKDLNLALNSARALGVSLPNTA 260
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 64.9 bits (151), Expect = 1e-09
Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 3/85 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLP-ILKVMG--AKQFHCGQIGSGQVAKLTN 172
DAPVSGGV A+ TL+ + G D LP L ++G +K F+ +G+G AK++N
Sbjct: 85 DAPVSGGVPAAEAGTLSMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKISN 144
Query: 173 NMLMGITGMATAECMNMGIKMGLEP 247
N L G +ATAE + +G+K GL+P
Sbjct: 145 NYLSGTILLATAEALAIGVKHGLDP 169
Score = 39.5 bits (88), Expect = 0.055
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPT--APSSRNYDGGFKNELMVKDLEL 398
V+ NS+ +SW + P+P + PS+ Y GFK ++M+KDL L
Sbjct: 175 VIKNSTGQSWMCDHVLPIPNVQTEYWVPSNSGYKPGFKTQMMLKDLGL 222
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 64.5 bits (150), Expect = 2e-09
Identities = 32/81 (39%), Positives = 47/81 (58%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+N TLA M GG ++ + P+L V+G + G G GQ K++NN+
Sbjct: 117 DAPVSGGDIGAKNGTLAIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNNIG 176
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T + AE + GL+
Sbjct: 177 VAATVITMAESLVYAKAAGLD 197
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 64.1 bits (149), Expect = 2e-09
Identities = 32/102 (31%), Positives = 57/102 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP++G +GA++A L FM G + E ++ P+ MG K H G++G GQ +K++ N+
Sbjct: 112 DAPITGSKIGAESAQLIFMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASKISLNLQ 171
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGVL 307
+ E + ++G+ P+ F +L+ S +V GV+
Sbjct: 172 IACIYEGFIEGFKVATQLGVNPEKF---VELVQSTMVRSGVV 210
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 63.7 bits (148), Expect = 3e-09
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+N TLA M GG ++ F + PI +++G+ G GSGQ K+ N +
Sbjct: 118 DAPVSGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTKMVNQIA 177
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ + E + + GL P
Sbjct: 178 IASNMIGVTEAIIYAERAGLNP 199
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 63.3 bits (147), Expect = 4e-09
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKED-FERSLPILKVMGAKQFHCGQIGSGQVAKLTNNM 178
DAPVSG GA+ A L FM G + ER+ +L +G + FH G +G+G K NN
Sbjct: 122 DAPVSGARAGAEAADLVFMIGCDDDAVLERTRAVLSCLGNRLFHLGPVGAGHAMKALNNY 181
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
+ +A AE M +G ++GL+P
Sbjct: 182 VSAAGYVAAAEAMIIGTEVGLDP 204
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 62.9 bits (146), Expect = 5e-09
Identities = 32/82 (39%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPVSGGV+GA+ +L MA E F P+L +GA+ FH G + G G K N +
Sbjct: 124 DAPVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVKAVNQL 183
Query: 179 LMGITGMATAECMNMGIKMGLE 244
L G+ A AE +++ ++G++
Sbjct: 184 LCGVHIAAAAEALSLAERVGVD 205
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/82 (40%), Positives = 44/82 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D+PVSGG+ GA+ TLA M + ++ P+LK G + G GQ KL NN+L
Sbjct: 120 DSPVSGGIGGAERGTLAVMTACPQPLYDELAPVLKNFGRLFYMGAGPGLGQTMKLANNLL 179
Query: 182 MGITGMATAECMNMGIKMGLEP 247
T+E M MG K GL+P
Sbjct: 180 SAAAVAITSEAMAMGAKAGLDP 201
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 62.5 bits (145), Expect = 7e-09
Identities = 33/81 (40%), Positives = 44/81 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG V A N TL + GG + I ++G K FH G +G G AKL N L
Sbjct: 119 EAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLNSL 178
Query: 182 MGITGMATAECMNMGIKMGLE 244
+GI G A +E M M + G++
Sbjct: 179 LGIFGEAYSEAMLMARQFGID 199
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 62.5 bits (145), Expect = 7e-09
Identities = 31/81 (38%), Positives = 43/81 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ L+ M GG + ER P+L GA G +G+GQ+ K+ N +L
Sbjct: 118 DAPVSGGQAGAEAGRLSVMCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKMVNQIL 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ AE +N GL+
Sbjct: 178 VAGAIEGAAEALNFAAAAGLD 198
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 62.5 bits (145), Expect = 7e-09
Identities = 34/80 (42%), Positives = 43/80 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG V A+ L + GGR D ER+ P L V+G + H G G+G KL NM
Sbjct: 118 DAPVSGTVAPAREGQLLVLVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTMKLVLNMT 177
Query: 182 MGITGMATAECMNMGIKMGL 241
M A AE + +G + GL
Sbjct: 178 MACFWGALAESLAVGQQFGL 197
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 62.5 bits (145), Expect = 7e-09
Identities = 36/84 (42%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPVSGG GA+ TLA MA G E + V+G K F G + G GQ+ KL NNM
Sbjct: 128 DAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQLLKLLNNM 186
Query: 179 LMGITGMATAECMNMGIKMGLEPK 250
L T+E G++ GL+P+
Sbjct: 187 LSSTAFAITSEAFVAGVRGGLDPE 210
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 62.5 bits (145), Expect = 7e-09
Identities = 32/80 (40%), Positives = 43/80 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+N TL M GG LP+L +G K H G G+GQV K N ++
Sbjct: 118 DAPVSGGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIM 177
Query: 182 MGITGMATAECMNMGIKMGL 241
+ +A E + K G+
Sbjct: 178 VAAQMVALGEILVFCEKCGV 197
Score = 36.7 bits (81), Expect = 0.39
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +3
Query: 240 SNRSSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALG 419
S + ++ + + SA+ W+ +V P + N GFK L KD+ + A
Sbjct: 198 SGPTVIEAIKSGSAQCWTLDVK-------PDRLFAGNRAPGFKAALQSKDMGIVMDTAKE 250
Query: 420 IRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
P+P AV TQL++ + G G +D S
Sbjct: 251 FGVPLPSTAVNTQLFQAMVQNGDGDRDNS 279
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 62.5 bits (145), Expect = 7e-09
Identities = 30/82 (36%), Positives = 46/82 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+ TL+ M GG + FER P+ +++G G G GQ K+ N ++
Sbjct: 116 DAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKVANQII 175
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ + A +E + K G +P
Sbjct: 176 VALNIEAVSEALLFASKAGADP 197
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 62.1 bits (144), Expect = 9e-09
Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+NATL+ M GG E FE+ +L +G + G+ G+GQ K+ N +
Sbjct: 118 DAPVSGGDVGAKNATLSIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIA 177
Query: 182 M--GITGMATAECMNMGIKMGLEPKFFGRAEQLIGS 283
+ I G+ A G+ + ++ +E GS
Sbjct: 178 LAGAIAGVCEAITYAKGVGLDVQTMLDSISEGAAGS 213
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 62.1 bits (144), Expect = 9e-09
Identities = 34/85 (40%), Positives = 44/85 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG + AQ L F+AGG +R P+L MG+ CG +G G KL N+L
Sbjct: 118 DAPVSGSKIPAQTGKLVFLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKLAMNLL 177
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
M A AE + + GLE + F
Sbjct: 178 MSGMVQALAESLLLVRNSGLEDQLF 202
Score = 33.5 bits (73), Expect = 3.6
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +3
Query: 300 VYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQS 479
++ P+ G+ A +R+++ F L+ KDL L AL +P G Q Y
Sbjct: 211 LFAPILGMKGQAFLNRDFEPHFPLHLLYKDLNLIHAQALEHHVALPAGDAIRQGYAQAMQ 270
Query: 480 RGYGQKDFS 506
+G G D +
Sbjct: 271 QGLGGLDIA 279
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 62.1 bits (144), Expect = 9e-09
Identities = 36/85 (42%), Positives = 46/85 (54%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+NATLA AGG + R P+ +G K + G G GQ AKL N ++
Sbjct: 166 DAPVSGGDRGAKNATLAIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQYAKLANQII 224
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+ T + E M K GL+ F
Sbjct: 225 IASTMLGLIEGMMYAYKSGLDVALF 249
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 61.7 bits (143), Expect = 1e-08
Identities = 31/71 (43%), Positives = 41/71 (57%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG GA+ TL+ + GG K DF+ LP+ + MG H G G+GQ AKL N
Sbjct: 152 DAPVTGGDTGAKAGTLSILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAKLANQ-- 209
Query: 182 MGITGMATAEC 214
+ I G + C
Sbjct: 210 IAIAGALSGVC 220
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/81 (39%), Positives = 43/81 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV AQN L MAGGR EDF + P+ + K H G GSG K+ NN +
Sbjct: 128 DAPVGRTPKDAQNGALLIMAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMKIANNYM 187
Query: 182 MGITGMATAECMNMGIKMGLE 244
++ + TAE + M K G++
Sbjct: 188 SMVSMVLTAETLAMARKAGID 208
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/80 (38%), Positives = 41/80 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+N TL M GG +E ++ LPI K G G G GQ K+ N ++
Sbjct: 118 DAPVSGGDLGAKNGTLTIMVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLM 177
Query: 182 MGITGMATAECMNMGIKMGL 241
+ T E + GL
Sbjct: 178 IAGTMTGLTEMLVYANATGL 197
Score = 34.7 bits (76), Expect = 1.6
Identities = 22/78 (28%), Positives = 36/78 (46%)
Frame = +3
Query: 255 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 434
L+ + SA +WS Y P +Y GF + +KDL++A A + P+
Sbjct: 203 LETVGGGSAANWSLSNYGP-------RILKEDYTPGFFVKHFIKDLKIALDEAKKLDLPL 255
Query: 435 PLGAVATQLYRIVQSRGY 488
P AT+LY + +G+
Sbjct: 256 PATQKATELYESLADKGF 273
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/80 (38%), Positives = 45/80 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+ PVSG A++ L +A G K FE S+P V+G + F+ GQ+G+G KL NM+
Sbjct: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMI 176
Query: 182 MGITGMATAECMNMGIKMGL 241
MG A +E + + K GL
Sbjct: 177 MGSMMNAFSEGLVLADKSGL 196
>UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 414
Score = 60.1 bits (139), Expect = 4e-08
Identities = 34/85 (40%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Frame = +3
Query: 261 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 440
V+N SS SWS+ V P+ +P P+SR Y GGF+ LM+KD+ LA A PL
Sbjct: 292 VINTSSGSSWSSRVNPPISS-IPGTPASRGYSGGFQTRLMLKDVNLALQAANKHNLATPL 350
Query: 441 GAVATQLYRIVQSRGYG---QKDFS 506
+ + +Y + S G G KDFS
Sbjct: 351 TSASKSIYEAICSDGDGDWASKDFS 375
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 7/145 (4%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFER-SLPILKVMGAK--QFHCGQIGSGQVAKLTN 172
DAPVSGG + A+ L M G R ++P+L++M + CG G+G K+ N
Sbjct: 202 DAPVSGGTVAAERGELTIMFGSPAPIATRLAMPLLQMMAREGGVIECGGSGTGVGVKVCN 261
Query: 173 NMLMGITGMATAECMNMG----IKMGLEPKFFGRAEQLIGSLLVDRGVLSSPRTGAHRSV 340
N+++ +A +E + +G I + L + S V+ + S P T A R
Sbjct: 262 NLVLASNQIALSEGLALGRSLNIDIALLQSVINTSSGSSWSSRVNPPISSIPGTPASRGY 321
Query: 341 E*KLRWRLQKRTYG*GLRISQWHGV 415
+ RL + L+ + H +
Sbjct: 322 SGGFQTRLMLKDVNLALQAANKHNL 346
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 59.7 bits (138), Expect = 5e-08
Identities = 30/80 (37%), Positives = 44/80 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APV+ V A L+ GG K+ FE+ PI V+G K FH G+ G+G KL N+L
Sbjct: 122 EAPVTNAVDMAALGRLSIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLL 181
Query: 182 MGITGMATAECMNMGIKMGL 241
++ A E + +G K G+
Sbjct: 182 WFVSAAAIGEGLMLGAKAGI 201
Score = 32.7 bits (71), Expect = 6.3
Identities = 21/70 (30%), Positives = 35/70 (50%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
+ + +S+ SW E VP + + +YD F L KDL L +G+A +P
Sbjct: 208 EAIKSSAGNSWVAEH--DVPSIF-----AGHYDPSFSLALCCKDLGLINGIAKSQGYDLP 260
Query: 438 LGAVATQLYR 467
+G +A QL++
Sbjct: 261 MGGMAQQLFQ 270
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 59.7 bits (138), Expect = 5e-08
Identities = 28/82 (34%), Positives = 41/82 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVS G L +AGG + D +R P+ ++ G + G +GS Q+ KL NN L
Sbjct: 130 DAPVSNGAPDESGRQLVVLAGGDRRDVDRCAPVFELFGRTVVYTGDVGSAQLTKLVNNAL 189
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ A E + +GL+P
Sbjct: 190 FIVHRSAAIEALRAAGTLGLDP 211
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 59.7 bits (138), Expect = 5e-08
Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQ--FHCGQIGSGQVAKLTNN 175
DAPVSG +GA N L GG D ER P+ + MG + H G G+G KL N
Sbjct: 140 DAPVSGMSVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYAVKLMIN 199
Query: 176 MLMGITGMATAECMNMGIKMGLE 244
L +ATAE ++ G+K G++
Sbjct: 200 QLWFSHLVATAEVLSTGVKAGVD 222
Score = 34.3 bits (75), Expect = 2.1
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQK 497
+YD GF L KDL L+ +A + P+ L + QLYR ++ YG K
Sbjct: 252 DYDEGFAIALACKDLGLSVDLARSVGVPMELSGLVEQLYRRAKAL-YGDK 300
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 59.7 bits (138), Expect = 5e-08
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLM 184
APVSG A L +A G K+ +ER LP+L+ MG K ++ G + K+ NM++
Sbjct: 124 APVSGSTTTAAAGALTILASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLKVAINMML 183
Query: 185 GITGMATAECMNMGIKMGLE 244
G+T E + +G + G+E
Sbjct: 184 GVTAGMLGEALALGERGGVE 203
Score = 33.5 bits (73), Expect = 3.6
Identities = 18/55 (32%), Positives = 27/55 (49%)
Frame = +3
Query: 339 SSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDF 503
++RN+ F M KD +LA P+PL AV+ Q + + G G+ DF
Sbjct: 229 TTRNFAPMFTASQMAKDFDLALEAGRDANVPMPLAAVSRQFLGAMIASGRGELDF 283
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG GA TL M GG K+ + P+L ++G + G G+GQ KL NNML
Sbjct: 118 DCPVSGGPAGADAGTLTIMVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNML 177
Query: 182 M-GITGMATAECMNMGIKMGLEPKFFGRAEQ 271
+ GIT + +E M + G+ + + Q
Sbjct: 178 VAGITTL-LSETMAVASDHGVSRRLLAQIIQ 207
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 59.3 bits (137), Expect = 6e-08
Identities = 27/80 (33%), Positives = 42/80 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG +GA+ T+ + GG + F + P+L+ M K H G G+G K+ NN+L
Sbjct: 127 DGPVSGGPLGARTGTMTMVVGGDEAGFTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLL 186
Query: 182 MGITGMATAECMNMGIKMGL 241
+ +E M + G+
Sbjct: 187 CAANLVLMSEMAQMAERAGI 206
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 59.3 bits (137), Expect = 6e-08
Identities = 30/83 (36%), Positives = 46/83 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG A++ L +A G K ++ +P V+G K F G+IG+G KL NM+
Sbjct: 117 EAPVSGSKKPAEDGQLVILAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKMKLVVNMI 176
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
MG A +E +++ GL P+
Sbjct: 177 MGSMMNALSEGLSLADNSGLSPQ 199
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 58.8 bits (136), Expect = 8e-08
Identities = 27/81 (33%), Positives = 45/81 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D+P+SGG A L MAGG +D + + +L+ + + H G +G+GQ KL N +L
Sbjct: 119 DSPLSGGAPKALIGELTLMAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVL 178
Query: 182 MGITGMATAECMNMGIKMGLE 244
G+ +A AE + + G++
Sbjct: 179 CGLGFLAVAEATQLALDAGVD 199
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 58.8 bits (136), Expect = 8e-08
Identities = 30/88 (34%), Positives = 47/88 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ T++FM GG + +R P+ ++ G G G+ +AKL + +
Sbjct: 117 DAPVSGGAQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVA 176
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRA 265
+ MA AE + +G GL + +A
Sbjct: 177 IIGNIMAMAEAVRLGTAGGLSAEMVKQA 204
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 58.8 bits (136), Expect = 8e-08
Identities = 27/80 (33%), Positives = 40/80 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG + L M GG + D E++ P+ H G +GSGQV K+ NN+L
Sbjct: 117 DAPVSGGAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLL 176
Query: 182 MGITGMATAECMNMGIKMGL 241
+ + +G +G+
Sbjct: 177 FTANLGSALSTLELGESLGI 196
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/82 (36%), Positives = 43/82 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+ TL M GG ++ F PIL+ +G G G+GQ K+ N +
Sbjct: 118 DAPVSGGDIGAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHTKMCNQIA 177
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ + E M + GL+P
Sbjct: 178 IATNMIGVCEAMAYAKRAGLDP 199
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 58.4 bits (135), Expect = 1e-07
Identities = 31/81 (38%), Positives = 45/81 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A+ TLA M GG ++ E + P+L+ +G + H G IG+GQ KL N +L
Sbjct: 119 DAPVSGGPGAAETGTLAIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQVL 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
AE + + G++
Sbjct: 178 CLTNYCVAAEALRLAQAYGVD 198
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/81 (40%), Positives = 41/81 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA TLA MAGG E PIL+ A+ G G+GQ KL N +
Sbjct: 123 DAPVSGGTSGAAAGTLAIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQTI 182
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T A AE + G++
Sbjct: 183 VMTTIAALAEATRLARHAGID 203
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 31/82 (37%), Positives = 42/82 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA+N TL+ MAGG + F+ P MG G G+GQ K+ N +
Sbjct: 122 DAPVSGGDIGAKNGTLSIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMANQIA 181
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ T E + GL+P
Sbjct: 182 VAANLFGTVEAVCYAEAAGLDP 203
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 58.0 bits (134), Expect = 1e-07
Identities = 31/80 (38%), Positives = 43/80 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+SGG GA++ L+ M GG K +E PIL + G GSGQ+ K+ N +
Sbjct: 138 DAPISGGQAGAESGQLSVMVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLTKMVNQIC 197
Query: 182 MGITGMATAECMNMGIKMGL 241
+ A AE +N K+GL
Sbjct: 198 IAGLVQALAEGVNFSEKVGL 217
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 58.0 bits (134), Expect = 1e-07
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+SGG +GA+ L+ M GG E ER P+ + + H G+ G+G K N ++
Sbjct: 133 DAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKACNQIV 192
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T A AE M + L+
Sbjct: 193 VAATVNALAEAMALASTAALD 213
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 57.6 bits (133), Expect = 2e-07
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNM 178
DAPVSGG GA+N L+ M GG +E + P+++ A+ H G+ G+GQ AK N +
Sbjct: 127 DAPVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTAKAINQV 185
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/82 (35%), Positives = 46/82 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG A++ L F+ G + + R +L VMG +F G +G G KL NM+
Sbjct: 167 EAPVSGSKKPAEDGLLIFLTAGDESLYNRVASLLDVMGKSRFFLGDVGKGADMKLVVNMV 226
Query: 182 MGITGMATAECMNMGIKMGLEP 247
MG ++ +E + + K+GL+P
Sbjct: 227 MGSMMVSFSEGLLLSEKVGLDP 248
Score = 38.3 bits (85), Expect = 0.13
Identities = 19/52 (36%), Positives = 27/52 (51%)
Frame = +3
Query: 351 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
Y F + KDL LA +A + IP A A +LY++ +S G +DFS
Sbjct: 277 YPTAFPLKHQQKDLRLALALAESVSQSIPTVAAANELYKVAKSLGLADQDFS 328
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/81 (35%), Positives = 41/81 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+SG + AQ A L+FM GG D + + P+ MG+ G GSG AK+ NN+L
Sbjct: 112 DAPMSGAQIAAQEARLSFMLGGEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLL 171
Query: 182 MGITGMATAECMNMGIKMGLE 244
T ++ GL+
Sbjct: 172 AAANTAMTRLVLDWADAAGLD 192
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 57.2 bits (132), Expect = 3e-07
Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPVSGG A+ TLA + G E+ P+L+ +G + F G + G Q+ K+ NN+
Sbjct: 120 DAPVSGGPSAARAGTLAMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNV 179
Query: 179 LMGITGMATAECMNMGIKMGLE 244
+M + AE + MG K GL+
Sbjct: 180 VMAANLVVCAEGLAMGAKAGLD 201
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APV+G A+NA L F+ GG ++ P +++MG K H G I K+ N L
Sbjct: 117 EAPVAGTKSHAENAELVFLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILINYL 176
Query: 182 MGITGMATAECMNMGIKMGLEPKF 253
+ +A AE + +G K GL+ +F
Sbjct: 177 LAQGMLAFAEALVVGEKQGLDRRF 200
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/80 (36%), Positives = 42/80 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A+ TL MAGG ++ ++ P+ G +GSGQVAK+ NN+L
Sbjct: 117 DAPVSGGEPAAKAGTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLL 176
Query: 182 MGITGMATAECMNMGIKMGL 241
A + +G +G+
Sbjct: 177 FSANLGAAMSALELGEALGV 196
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 56.8 bits (131), Expect = 3e-07
Identities = 29/81 (35%), Positives = 39/81 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A L M GG + R P+L+ H G +GSGQVAKL NN +
Sbjct: 131 DAPVSGGGDAAAQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVAKLVNNFV 190
Query: 182 MGITGMATAECMNMGIKMGLE 244
E + ++G++
Sbjct: 191 FTAQVGLALETFSFAQRLGMD 211
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 56.8 bits (131), Expect = 3e-07
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG+ GA+ TL FM GG + ++ M + G +GQ AK+ NN++
Sbjct: 118 DAPVSGGMSGAKAGTLTFMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLM 177
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+ I +TAE + ++GL+ + F
Sbjct: 178 LFINLASTAEGAVLAERLGLDKQVF 202
Score = 52.4 bits (120), Expect = 7e-06
Identities = 28/84 (33%), Positives = 44/84 (52%)
Frame = +3
Query: 258 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 437
D+ + SS SW+ + PV G+VPTA S+ ++ F EL KD+ LA A +P+
Sbjct: 204 DIASVSSGDSWALRTWYPVGGVVPTAASNNDFAPTFTTELANKDIGLAISAARDTGTPLE 263
Query: 438 LGAVATQLYRIVQSRGYGQKDFSL 509
+G L++ + G KD S+
Sbjct: 264 IGEHVQTLFQRLIDSGQSGKDCSM 287
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 56.4 bits (130), Expect = 4e-07
Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC-GQIGSGQVAKLTNNML 181
APVSGG A L MA G +ER+ P+L +G F+ G + GQ KL NN L
Sbjct: 120 APVSGGTAAAAQGVLTVMAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQTLKLINNTL 179
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+A+ E + G K GL+ +
Sbjct: 180 YASAMLASCEALVCGAKAGLDAR 202
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 56.4 bits (130), Expect = 4e-07
Identities = 26/72 (36%), Positives = 41/72 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+AP++G V A + TL F+ GG + D E + P+L +G H G +G+G AKL N+L
Sbjct: 124 EAPMTGSVHDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKLALNLL 183
Query: 182 MGITGMATAECM 217
+G+ E +
Sbjct: 184 VGVMAGGLGEAI 195
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 56.4 bits (130), Expect = 4e-07
Identities = 28/80 (35%), Positives = 43/80 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
++PV G V+ A+N L + G +E FER P L+ +G + F+ + G KL NN +
Sbjct: 108 ESPVIGSVIPARNGQLTILVSGEREAFERVRPYLQKLGKRIFYFNEPGKATKLKLINNFV 167
Query: 182 MGITGMATAECMNMGIKMGL 241
+G A E + +G K GL
Sbjct: 168 LGAFMAALGEAIALGEKAGL 187
Score = 39.9 bits (89), Expect = 0.041
Identities = 18/54 (33%), Positives = 30/54 (55%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSL 509
+Y F + +VKDL A +A+ R +PL A ++YR+ +G + DFS+
Sbjct: 217 DYSTHFSVKNLVKDLSYAYDLAVASRKAVPLNATVREIYRLAFEKGLEELDFSV 270
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 56.0 bits (129), Expect = 6e-07
Identities = 32/72 (44%), Positives = 41/72 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGGV GA TLA MAGG + + + MG + + G G+GQ+ KL N +
Sbjct: 125 DAPVSGGVPGATAGTLAIMAGGDEALISGLVDVFAPMG-RLTYVGPSGAGQLCKLANQQI 183
Query: 182 MGITGMATAECM 217
+ IT A AE M
Sbjct: 184 VAITIGAVAEAM 195
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 56.0 bits (129), Expect = 6e-07
Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNML 181
A VSGG GA+ TL+ MA G ++ + P +G+ F+ G + G+ Q AKL NN++
Sbjct: 122 AAVSGGSTGAEAGTLSIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLV 181
Query: 182 MGITGMATAECMNMGIKMGL 241
+GI A AE + G + L
Sbjct: 182 LGINMNAVAEGLKFGAQYNL 201
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 56.0 bits (129), Expect = 6e-07
Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQ-IGSGQVAKLTNNM 178
DAP+SGG A + M+ R +E++ +L M K + G G+G K+ N +
Sbjct: 120 DAPISGGAAKAAAGQMTVMSSARPAAYEKAGDVLAAMAGKVYRLGDCAGAGSKVKIINQL 179
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L G+ A AE M +G++ G++P
Sbjct: 180 LAGVHIAAAAEAMALGLREGVDP 202
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 55.6 bits (128), Expect = 8e-07
Identities = 28/81 (34%), Positives = 43/81 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV G V+ A L + GG KE FE + P+ + ++ G+ G G KL NN++
Sbjct: 118 DAPVLGSVIPALKGELTIVVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKLVNNIV 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
+G AE + +G K G++
Sbjct: 178 LGGIMEVLAEAIAIGEKAGID 198
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 55.6 bits (128), Expect = 8e-07
Identities = 30/81 (37%), Positives = 43/81 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSG ++ A+ L +AGG ER+ PIL G K H G GSG AKL N+L
Sbjct: 105 DVPVSGSLVPAEKGELLLLAGGDGAALERARPILLHFGKKILHFGPTGSGMKAKLVINLL 164
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ + + + +G +GL+
Sbjct: 165 LASHVESLVQTVLVGESLGLD 185
Score = 35.5 bits (78), Expect = 0.89
Identities = 21/59 (35%), Positives = 29/59 (49%)
Frame = +3
Query: 345 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSLSSSY 521
R+YD F LM KDL+L S L R+P L + +R + G G++D S Y
Sbjct: 213 RSYDKAFSARLMAKDLDLLSLTLLRNRTPASLPFELGRHFRELVESGRGEEDVSALYEY 271
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 55.6 bits (128), Expect = 8e-07
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA LA M GG ++ R+ +L + A H G +G+GQ+ K N ML
Sbjct: 117 DAPVSGGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVKAANQML 176
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ E + + + G++
Sbjct: 177 VAGNIALVGEAVTLLQRTGVD 197
Score = 38.3 bits (85), Expect = 0.13
Identities = 20/55 (36%), Positives = 32/55 (58%)
Frame = +3
Query: 342 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
+R++ GF+ +L KDL++A A R +PL + TQL + ++S G G D S
Sbjct: 224 ARDFAPGFRIDLHYKDLKIALAAAEQARIAVPLTGIITQLVQALRSAGDGGLDHS 278
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 55.6 bits (128), Expect = 8e-07
Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVM-GAKQFHCGQIGSGQVAKLTNNM 178
DAPVSGG GA + +L+ GG + P+L + G K H G GSG V KL NN+
Sbjct: 116 DAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVLLALTGGKYSHIGGPGSGNVVKLLNNV 175
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L ++ E + + G++P
Sbjct: 176 LAAANLVSVGEALGVAKAYGIDP 198
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 55.2 bits (127), Expect = 1e-06
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQ-IGSGQVAKLTNNM 178
DAP+SGG A L +A G F ++ P L M AK + G G G K+ N +
Sbjct: 125 DAPISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFKMINQL 184
Query: 179 LMGITGMATAECMNMGIKMGLE 244
L G+ A +E M K GL+
Sbjct: 185 LAGVHIAAASEAMAFAAKQGLD 206
Score = 37.5 bits (83), Expect = 0.22
Identities = 16/43 (37%), Positives = 25/43 (58%)
Frame = +3
Query: 372 ELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKD 500
E+ VKDL + MA R P+P+ A A Q++ + + G G+ D
Sbjct: 243 EIFVKDLGIIQDMARSARFPVPVSAAALQMFLMTAAAGMGRDD 285
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/97 (35%), Positives = 48/97 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG A+ L F+ GG ++ PIL MG H G +G+G KL N L
Sbjct: 119 DAPVSGSRPQAEAGQLIFLVGGDAGAVAKAGPILNAMGGTVHHAGPLGNGAAVKLAINAL 178
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLV 292
+G+ A E + + G++ RA ++IGS V
Sbjct: 179 LGVQVAAMGELIALLRHCGIDEV---RAVEIIGSTSV 212
Score = 38.7 bits (86), Expect = 0.096
Identities = 24/72 (33%), Positives = 33/72 (45%)
Frame = +3
Query: 291 STEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRI 470
ST V P +A + NY F + LM KDL MA R+ PL A ++
Sbjct: 209 STSVCSPAARGAASAMAVGNYAPLFPSALMEKDLGYLQNMAAAHRARAPLTQAARSVFGE 268
Query: 471 VQSRGYGQKDFS 506
SRGYG+ + +
Sbjct: 269 AMSRGYGEDNMT 280
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/81 (38%), Positives = 43/81 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA + L M GG+ ER+ I + H G IGSGQ+ K+ N +
Sbjct: 119 DAPVSGGEQGAISGQLTIMCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTKMVNQIC 178
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ A AE ++ G + GL+
Sbjct: 179 VAGLIEALAEGIHFGQQAGLD 199
Score = 38.7 bits (86), Expect = 0.096
Identities = 21/52 (40%), Positives = 29/52 (55%)
Frame = +3
Query: 351 YDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
YD GF + M KDLE+ A + + +P A+ QLY +Q G+GQ D S
Sbjct: 229 YDFGFAVDHMRKDLEICLKEAKKMNTSLPSTAMVDQLYGELQQSGHGQLDTS 280
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV G GA+ L + GG + + P+L+ H G +GSGQVAK NNML
Sbjct: 114 DAPVVFGRQGAKEGQLGSLCGGDDKQVAKITPVLESYSKAVHHVGPVGSGQVAKACNNML 173
Query: 182 MGITGMATAECMNMGIKMGLE 244
+A E +++ + G++
Sbjct: 174 HWAACVANFEVLSLAKRYGID 194
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG +GA++ TLA +AGG + P+ + +G + G GSGQ +K+ N +
Sbjct: 133 DAPVSGGDVGARDGTLAILAGGDEGVVHWLSPLFEALGRATW-MGPAGSGQSSKIANQIT 191
Query: 182 MGITGMATAECMNMGIKMGLE-PKF 253
+G T + +E + + GL+ P+F
Sbjct: 192 IGGTILGLSEAIVFAGRAGLDVPRF 216
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/81 (37%), Positives = 40/81 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+SG A N L M GG E +R PI ++ H G GSG AKL + L
Sbjct: 136 DAPMSGSPKQAFNNQLVLMVGGPAEQVQRVSPIFRMYADHIHHMGANGSGTAAKLLSQAL 195
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ A AE M + ++G+E
Sbjct: 196 VASHNAAAAEAMTIANRLGIE 216
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQ---FHCGQIGSGQVAKLTN 172
D PVSGG A + TL+ MAG +E IL+VM + G +G+G K+ +
Sbjct: 123 DCPVSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKMVH 182
Query: 173 NMLMGITGMATAECMNMGIKMGLEPKFFGRAEQLIGS 283
+L GI + +E M ++GL+ K AE++IGS
Sbjct: 183 QVLAGIHILGASEAMGFAAQLGLDAK--TTAEKIIGS 217
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 54.8 bits (126), Expect = 1e-06
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+SG A+ L + GG + +R+ P+L V+G H G GS KL N +
Sbjct: 114 DAPMSGSTPEAETGDLVMLVGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKLVVNGV 173
Query: 182 MGITGMATAECMNMGIKMGLE 244
MG T AE ++ G+ GL+
Sbjct: 174 MGATLNVIAEGVSYGLAAGLD 194
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/82 (37%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPVSGGV GA+ TL M G + R P+L + ++ G + G Q KL NN
Sbjct: 115 DAPVSGGVTGARARTLTVMYAGTDDACARVEPVLAALSDRRRRVGDRPGLAQALKLANNF 174
Query: 179 LMGITGMATAECMNMGIKMGLE 244
L + AT+E + G GL+
Sbjct: 175 LAAVALAATSEAVAFGTSAGLD 196
Score = 33.5 bits (73), Expect = 3.6
Identities = 23/70 (32%), Positives = 32/70 (45%)
Frame = +3
Query: 255 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 434
LDVLN +S ++ +T P L + Y GF N LM KDL L + P
Sbjct: 201 LDVLNTASGQNNATAEKFPRQVL------TERYSAGFANSLMAKDLRLYLQEVRELDGPT 254
Query: 435 PLGAVATQLY 464
LG V + ++
Sbjct: 255 SLGTVTSSVW 264
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPVSGG A + MA G E FE+ P+L AK ++ G +IG G K+ + +
Sbjct: 122 DAPVSGGAAKAATGDMTVMASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQL 181
Query: 179 LMGITGMATAECMNMGIKMGL 241
L G+ A AE M + + +
Sbjct: 182 LAGVHIAAGAEAMALAARANI 202
Score = 36.7 bits (81), Expect = 0.39
Identities = 15/45 (33%), Positives = 27/45 (60%)
Frame = +3
Query: 372 ELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
++ VKDL L + A ++ P+PL + A ++ + G+GQ+D S
Sbjct: 240 DIFVKDLNLVADTAKELKFPLPLSSTALNMFLSASNAGFGQEDDS 284
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/77 (38%), Positives = 37/77 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG V A + L M GG ++ F + P+L MG H G G G AKL N L
Sbjct: 129 DAPVSGSVKQATDGQLVIMVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKLAINTL 188
Query: 182 MGITGMATAECMNMGIK 232
+ I AE + K
Sbjct: 189 LAIYTEGLAEIVTFSRK 205
>UniRef50_A1WS34 Cluster: Putative uncharacterized protein; n=1;
Verminephrobacter eiseniae EF01-2|Rep: Putative
uncharacterized protein - Verminephrobacter eiseniae
(strain EF01-2)
Length = 173
Score = 54.4 bits (125), Expect = 2e-06
Identities = 26/55 (47%), Positives = 35/55 (63%)
Frame = +3
Query: 297 EVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQL 461
E Y P+PG++ T+P S+NY GGF +LM KD LA A +R+ PLG +A L
Sbjct: 13 EKYDPMPGVMETSPVSKNYAGGFGTDLMPKDPGLAQENAPAVRAATPLGGLARSL 67
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/78 (35%), Positives = 42/78 (53%)
Frame = +2
Query: 11 VSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 190
VSG A+ A L + G + +ER P+L +G QF+ G ++ KL N+L+ +
Sbjct: 117 VSGNNHMAEAAKLTALVSGPADAYERIKPLLAALGPAQFYLGDAEQARLMKLVVNLLIAL 176
Query: 191 TGMATAECMNMGIKMGLE 244
TG AE + +G K GLE
Sbjct: 177 TGGMLAEALTLGSKGGLE 194
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 54.0 bits (124), Expect = 2e-06
Identities = 30/83 (36%), Positives = 42/83 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV G + + L + GG K+ F+ I K + + G G G +KL NN+L
Sbjct: 114 DAPVIGTSVFVEQKKLVVLVGGPKDKFDIVNDIAKETASLVVYMGPNGMGLYSKLVNNLL 173
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+ A AE N GI+ GLEP+
Sbjct: 174 LASYVAAIAEAYNFGIRAGLEPQ 196
Score = 37.5 bits (83), Expect = 0.22
Identities = 24/77 (31%), Positives = 41/77 (53%)
Frame = +3
Query: 273 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVA 452
SSARS +TE+ P L+ +Y F + M KDLE+ A ++ P+ ++
Sbjct: 206 SSARSPTTEL--KAPKLL-----KEDYSTQFATKHMRKDLEIIMREAQNLKIITPVSSLV 258
Query: 453 TQLYRIVQSRGYGQKDF 503
+LY++ ++ GY + DF
Sbjct: 259 LELYKMAEALGYSEADF 275
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 54.0 bits (124), Expect = 2e-06
Identities = 29/80 (36%), Positives = 41/80 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+ G + + + GG +E +ER+ ++K H G G G AKL NN L
Sbjct: 119 DAPIIGTSILIEKREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAKLINNAL 178
Query: 182 MGITGMATAECMNMGIKMGL 241
+G A AE +N+G MGL
Sbjct: 179 LGSYVAALAEVVNLGEAMGL 198
Score = 44.4 bits (100), Expect = 0.002
Identities = 30/85 (35%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
Frame = +3
Query: 255 LDVLNN-SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 431
+DVL SSARS ++E+ VP ++ + ++ F + M KDL+L + A + P
Sbjct: 204 MDVLTKLSSARSPTSEL--KVPKMI-----NNDFTTQFATKHMRKDLDLVNKEASRLGVP 256
Query: 432 IPLGAVATQLYRIVQSRGYGQKDFS 506
+P+ A+A QLYR+ ++ G DFS
Sbjct: 257 VPMAALALQLYRMSEADGLSDDDFS 281
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/70 (40%), Positives = 37/70 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+ TL M GG ++ + + P L G K G+ G+G K NNML
Sbjct: 134 DAPVSGGTSGAEAGTLTVMLGGPADEIDAASPHLAFAG-KVVRVGETGAGFAVKAVNNML 192
Query: 182 MGITGMATAE 211
+ + A E
Sbjct: 193 LAVNLWAAGE 202
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/81 (34%), Positives = 38/81 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+ A++ L M G K F+R P+L +G FH G +G+G KL NN
Sbjct: 126 DAPLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIKLINNCY 185
Query: 182 MGITGMATAECMNMGIKMGLE 244
T A AE + G+E
Sbjct: 186 SMTTACAMAEAFAIADATGIE 206
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 53.6 bits (123), Expect = 3e-06
Identities = 30/81 (37%), Positives = 43/81 (53%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+ AQ TLA M G E F P++ + CG +G GQV K+ NNM+
Sbjct: 124 DAPVARTRAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMI 183
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ T +A +E +G K G++
Sbjct: 184 LFETVVAISEAKAIGEKAGVD 204
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 53.2 bits (122), Expect = 4e-06
Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D+PV M AQ TL +A G +D R+ L MG + CG++G G K+ NN
Sbjct: 120 DSPVGRSAMEAQRGTLLILASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVKVVNN-F 178
Query: 182 MGIT-GMATAECMNMGIKMGL 241
MGI+ TAE + + GL
Sbjct: 179 MGISLNALTAEALTLAEASGL 199
Score = 39.1 bits (87), Expect = 0.072
Identities = 19/49 (38%), Positives = 31/49 (63%)
Frame = +3
Query: 360 GFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
GF+ +L KDL LA +A R+ +P+G+ A Q Y +++G G +D+S
Sbjct: 234 GFQVDLAHKDLGLALELAARSRACVPMGSAAFQSYTAARAQGRGGQDYS 282
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 53.2 bits (122), Expect = 4e-06
Identities = 27/80 (33%), Positives = 40/80 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSG V A+ L M GG + P+L ++G + FH G +GSG KL N +
Sbjct: 119 DVPVSGSVAVAREGGLTLMVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTV 178
Query: 182 MGITGMATAECMNMGIKMGL 241
+ A AE + + + G+
Sbjct: 179 IHGLNAALAEGLVLAERAGI 198
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 53.2 bits (122), Expect = 4e-06
Identities = 34/97 (35%), Positives = 52/97 (53%), Gaps = 3/97 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMG-AKQFHC--GQIGSGQVAKLTN 172
D PVSGG A + TL+ MAG +E IL+VM K+ + G IG+G K+ +
Sbjct: 123 DCPVSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKMVH 182
Query: 173 NMLMGITGMATAECMNMGIKMGLEPKFFGRAEQLIGS 283
+L GI + +E M ++GL+ K A ++IG+
Sbjct: 183 QVLAGIHILGASEAMGFAAQLGLDAK--TTAAKIIGT 217
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 52.8 bits (121), Expect = 6e-06
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQI-GSGQVAKLTNNM 178
DAP+SGG A L +A G F ++ P L M AK + G G G K+ N +
Sbjct: 149 DAPISGGAQRAAEGALTILASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMINQL 208
Query: 179 LMGITGMATAECMNMGIKMGLE 244
L G+ A +E + + GL+
Sbjct: 209 LAGVHIAAASEAVAFAARQGLD 230
Score = 34.7 bits (76), Expect = 1.6
Identities = 14/43 (32%), Positives = 24/43 (55%)
Frame = +3
Query: 372 ELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKD 500
++ VKDL + MA + P+P+ A A Q++ + G G+ D
Sbjct: 267 DIFVKDLGIIQDMARSAKFPVPVSAAALQMFLATSAAGMGRDD 309
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 52.4 bits (120), Expect = 7e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Frame = +2
Query: 14 SGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 193
S G LA +A G + FER P+L++M + +CG+IGSG KL +N + +
Sbjct: 141 SEGATSEGGMGLAVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNAVNAVA 200
Query: 194 GMATAECMNMGIKMGL 241
A +E + +G+ G+
Sbjct: 201 VQAVSEGITLGLAQGI 216
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 52.4 bits (120), Expect = 7e-06
Identities = 26/81 (32%), Positives = 40/81 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG GA+N L M GG + F+ P++ G +G+GQ+ K+ N +
Sbjct: 119 DAPVSGGQAGAENGALTVMMGGDQAHFDTVKPVISAYSRCAELLGPVGAGQLTKMVNQIC 178
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ AE ++ GL+
Sbjct: 179 IAGVVQGLAEGLHFAKSAGLD 199
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D+PVSGG GA+ TL AGG + + I V+ + G G+GQ K+ N ++
Sbjct: 118 DSPVSGGTSGAEQGTLVIFAGGNESTIQDLGLIYNVLSQRVTRMGDTGTGQATKICNQLI 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ AE + + + G++
Sbjct: 178 VAANSALIAEAVALAHRAGVD 198
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 52.0 bits (119), Expect = 1e-05
Identities = 29/99 (29%), Positives = 47/99 (47%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A+ +L+ M GG + D + +++ + CG G+GQ+AK N ++
Sbjct: 122 DAPVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGRVVVCGGPGAGQIAKACNQLV 181
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDR 298
+ AE + +G +P E L+G R
Sbjct: 182 VTAGIAVVAEALVTASALGADPA--AVREALLGGYAASR 218
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 52.0 bits (119), Expect = 1e-05
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
D PVSGG GAQ TL MA G E + P+++ + A + G + G GQ K
Sbjct: 117 DTPVSGGFPGAQGGTLTMMAAGVDEVLDTYAPVMEAVSATIWCVGTEAGQGQTVKACLQS 176
Query: 179 LMGITGMATAECMNMGIKMGLEPKFF 256
L+G AT E + K G+ + F
Sbjct: 177 LLGAMFSATFEASVLAAKAGINGEVF 202
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/81 (34%), Positives = 39/81 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DA +SGG A+ L M GG + + +K H G+ G+G KL NN L
Sbjct: 117 DAGISGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSKVAHMGESGAGHTTKLLNNFL 176
Query: 182 MGITGMATAECMNMGIKMGLE 244
++ A+AE M G K GL+
Sbjct: 177 NAVSLSASAEVMVAGKKAGLD 197
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 52.0 bits (119), Expect = 1e-05
Identities = 34/109 (31%), Positives = 45/109 (41%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A LA M G E F+R + H G+ G+G KL NML
Sbjct: 123 DAPVSGGAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNML 182
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGVLSSPRTGA 328
++ A AE + GL+ G+ + S G + T A
Sbjct: 183 TFVSYAAAAEAQRLAEACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTA 231
>UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Verminephrobacter eiseniae EF01-2|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Verminephrobacter eiseniae (strain EF01-2)
Length = 293
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/132 (31%), Positives = 62/132 (46%), Gaps = 2/132 (1%)
Frame = +2
Query: 2 DAPVSGGV--MGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNN 175
DA + GV M A +ATLA GG+ + RS +L + ++Q H G +G+G AK+ NN
Sbjct: 111 DASILAGVEQMAAGSATLAL--GGKPDAIARSQGVLDAIASRQIHFGALGAGAAAKVINN 168
Query: 176 MLMGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGVLSSPRTGAHRSVE*KLR 355
+ + AE M G+ E+LI +LS PR G HR + +
Sbjct: 169 AVAHAVMVVVAEAGAMATAAGV------GCEKLI-------ALLSDPRMGLHRPLTYRYA 215
Query: 356 WRLQKRTYG*GL 391
R+ K Y G+
Sbjct: 216 QRVVKGDYTGGM 227
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 51.6 bits (118), Expect = 1e-05
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 6/106 (5%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG + GG + ER+ P+L G H G +G+GQ KL NN +
Sbjct: 117 DAPVSGGPHDIAAGAVTLFVGGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKLVNNTV 176
Query: 182 MGITGMATAECMNMGIKMGL-EPKFF-----GRAEQLIGSLLVDRG 301
E + +G +G+ EP G + + +++ RG
Sbjct: 177 FAAQIGLLREAVRLGGALGVAEPDLLTALTHGSSSSRVSNMIAGRG 222
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/81 (33%), Positives = 40/81 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+A ++ + A+ TL M GG+KE FER P+L+ M A G G K NM+
Sbjct: 127 EASMASSITQAREGTLYLMVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIKALVNMV 186
Query: 182 MGITGMATAECMNMGIKMGLE 244
M I AE + + +GL+
Sbjct: 187 MNINTAGLAEGLGLADALGLD 207
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC-GQIGSGQVAKLTNNM 178
DAPVSGGV A L MA G E + + +L + K + G G+G K+ N +
Sbjct: 473 DAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQL 532
Query: 179 LMGITGMATAECMNMGIKMGLEPK 250
L G+ + AE M G ++GL +
Sbjct: 533 LAGVHIASAAEAMAFGARLGLNTR 556
Score = 46.0 bits (104), Expect = 6e-04
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC-GQIGSGQVAKLTNNM 178
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 145 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 204
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L GI +A E +++G + G+ P
Sbjct: 205 LEGIHLVAAVEAISLGSQAGVHP 227
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC-GQIGSGQVAKLTNNM 178
DAPVSGGV A L MA G E + + +L + K + G G+G K+ N +
Sbjct: 440 DAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQL 499
Query: 179 LMGITGMATAECMNMGIKMGLEPK 250
L G+ + AE M G ++GL +
Sbjct: 500 LAGVHIASAAEAMAFGARLGLNTR 523
Score = 46.0 bits (104), Expect = 6e-04
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC-GQIGSGQVAKLTNNM 178
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 121 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 180
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L GI +A E +++G + G+ P
Sbjct: 181 LEGIHLVAAVEAISLGSQAGVHP 203
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 50.8 bits (116), Expect = 2e-05
Identities = 27/75 (36%), Positives = 38/75 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PVSGG GA N +L+ G ++D I +V+G + +G GQ K N +L
Sbjct: 113 DCPVSGGTEGAHNGSLSLFIGASEKDCLSFENIFQVLGKSINYFNGVGKGQQVKALNQIL 172
Query: 182 MGITGMATAECMNMG 226
+ T A AE M +G
Sbjct: 173 VAGTYAAVAEAMELG 187
Score = 34.7 bits (76), Expect = 1.6
Identities = 17/54 (31%), Positives = 29/54 (53%)
Frame = +3
Query: 360 GFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSLSSSY 521
GFK EL KDL +A+ +A I +P+ + ++ + + G G+ D S+ Y
Sbjct: 226 GFKLELHHKDLSIATELAKSINIDLPIASKVKEMEQRLMQTGLGELDVSVLHRY 279
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D +SG A L F GG E ++ L +L+V+ K G IG+ + KL NN++
Sbjct: 118 DIALSGEPPQAVLGELVFQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNNLM 177
Query: 182 -MGITGMATAECMNMGIKMGLEPK 250
+G +A AE +G+K G+EPK
Sbjct: 178 SLGNVAVA-AEAFVLGVKCGMEPK 200
Score = 32.7 bits (71), Expect = 6.3
Identities = 17/53 (32%), Positives = 25/53 (47%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
+Y FK L +KD+ L +A L V LYR RG G+++F+
Sbjct: 227 DYGASFKTSLALKDINLILDLANEEHYAARLAPVIASLYRDAVGRGLGEENFT 279
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 50.0 bits (114), Expect = 4e-05
Identities = 23/60 (38%), Positives = 31/60 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+ PVSGG A ++ AG + FER LP L +G + H G IGS + K+ N L
Sbjct: 114 ECPVSGGCHRADTGNISIFAGCDRATFERMLPTLTTLGRRVLHTGDIGSASILKVMTNYL 173
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 50.0 bits (114), Expect = 4e-05
Identities = 27/80 (33%), Positives = 38/80 (47%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG A++A L MAG D + V+G K G+ G+G KL NML
Sbjct: 118 DAPVSGATQAAKDAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMKLGVNML 177
Query: 182 MGITGMATAECMNMGIKMGL 241
+ AE +++ G+
Sbjct: 178 IHGLNQTLAEALSLTTAAGI 197
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 50.0 bits (114), Expect = 4e-05
Identities = 29/80 (36%), Positives = 39/80 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG A++ L F+ G + + R L VMG F G +G G KL NM+
Sbjct: 156 EAPVSGSKKPAEDGALIFLCAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNMI 215
Query: 182 MGITGMATAECMNMGIKMGL 241
MG A AE + + K L
Sbjct: 216 MGSMMGAFAEGLTLADKSDL 235
Score = 33.9 bits (74), Expect = 2.7
Identities = 17/53 (32%), Positives = 27/53 (50%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
NY F + KD+ LA +A + +P+ A A +LY+ + G +DFS
Sbjct: 265 NYPPAFPLKHQQKDMRLAIALADELAQDMPVAAAANELYKRARRDGCDDEDFS 317
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 49.6 bits (113), Expect = 5e-05
Identities = 28/81 (34%), Positives = 41/81 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PV+G A L + G D ER+ P L+ +G+ H G +GSG V KL NN++
Sbjct: 118 DCPVTGLPDAAAAGKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYKLINNLM 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
I AE + + + GL+
Sbjct: 178 GAIQIAGLAEGLAIAEQAGLD 198
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/82 (31%), Positives = 36/82 (43%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG A L M GG + +L + H G +G+G AKL NN +
Sbjct: 286 DAPVSGGQPRALAGELTIMIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKLINNTM 345
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ M G +G++P
Sbjct: 346 FAAQIALADDAMKAGESLGIDP 367
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 49.6 bits (113), Expect = 5e-05
Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQ-IGSGQVAKLTNNM 178
DAP++G +GA+ L M G +E R++P+ ++MG H + +G GQ AK NM
Sbjct: 129 DAPITGSKLGAEGGKLTIMVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRAKYCLNM 188
Query: 179 LMGI 190
+
Sbjct: 189 TQAV 192
Score = 35.5 bits (78), Expect = 0.89
Identities = 19/52 (36%), Positives = 27/52 (51%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDF 503
+++ F+ +LM KDL LA A R P+P V LY + G G +DF
Sbjct: 239 DFEPHFRLDLMHKDLHLALRHAENERVPLPAATVVRGLYDQAVAEGMGPRDF 290
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 49.2 bits (112), Expect = 7e-05
Identities = 27/81 (33%), Positives = 38/81 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSGG ++ AGG + ER P L H G +GSGQ KL NN +
Sbjct: 115 DAPVSGGPHDIAAGSVTVFAGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVKLVNNTM 174
Query: 182 MGITGMATAECMNMGIKMGLE 244
AE + + ++G++
Sbjct: 175 FAAQIGVVAEGVRLARELGVD 195
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 49.2 bits (112), Expect = 7e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC--GQIGSGQVAKLTNN 175
DAPVSGG A TL +A G ++ + + P+L M A H G +G+G K+ +
Sbjct: 127 DAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAM-ADPLHMIPGGLGAGTKVKMVHQ 185
Query: 176 MLMGITGMATAECMNMGIKMGLEPK 250
L GI + +E M +GL K
Sbjct: 186 ALAGIHMIMASEAMGFAAFLGLNTK 210
>UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4747-PA
- Apis mellifera
Length = 413
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/83 (28%), Positives = 39/83 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+A V G AQ TL +A G + F+ + MG F+ G++G+ L ++
Sbjct: 244 EAQVQGSKTQAQEGTLVILAAGDRTLFDECQSCFEAMGKNSFYLGEVGNASKMNLVLQLM 303
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
G+T AE M + + GL+ K
Sbjct: 304 AGVTLAGLAESMALADRAGLQQK 326
Score = 44.4 bits (100), Expect = 0.002
Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Frame = +3
Query: 354 DGGFKNEL----MVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
+GGF +L M KDL L+ GM+ + P+PL A A ++Y+ + GYG+ D S
Sbjct: 351 EGGFPTQLPLQHMQKDLRLSLGMSDQLEQPLPLAAAANEVYKHAKRLGYGEHDAS 405
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 48.4 bits (110), Expect = 1e-04
Identities = 22/72 (30%), Positives = 37/72 (51%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DA V G ++ MAGGR+E F+ + P+ + ++ F+ G G+G KL N+
Sbjct: 97 DATVLGSSKVVRSGAAVVMAGGRRESFDAASPLFRTFASRAFYLGPFGAGARMKLVVNLA 156
Query: 182 MGITGMATAECM 217
+G+ AE +
Sbjct: 157 LGLHRAVLAETL 168
>UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 299
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPVSGG GA+ +L MA G E+ + V+ K G Q G Q K+ NN+
Sbjct: 118 DAPVSGGAEGARTGSLTIMASGDPTTIEQCSSVFDVIAGKVIVVGNQPGQAQAIKVANNV 177
Query: 179 LMGITGMATAECMNMGIKMGL 241
L +ATAE + K G+
Sbjct: 178 LSLGALVATAEATAITRKAGI 198
Score = 34.7 bits (76), Expect = 1.6
Identities = 23/84 (27%), Positives = 40/84 (47%)
Frame = +3
Query: 249 SSLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 428
++L+ LN SS R+ +T V P L + +D GF +KD+ L +A +
Sbjct: 202 TALEALNASSGRNTATAVKFPRHVL------TGRFDFGFPTSGALKDVSLFLELAAELGV 255
Query: 429 PIPLGAVATQLYRIVQSRGYGQKD 500
PL + ++ +G+GQ+D
Sbjct: 256 EAPLSSAVQAIWHTAAEQGFGQQD 279
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
D PVSGG GAQ L +A G+ + + P ++ + G + G+ KL N +
Sbjct: 123 DGPVSGGATGAQAGALTIIASGQAQALAAAEPAMRACSSIIHRVGEEAGAASTVKLVNQL 182
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L TAE + +G + G++P
Sbjct: 183 LTASHIALTAEALALGARAGVDP 205
Score = 33.5 bits (73), Expect = 3.6
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = +3
Query: 372 ELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYG 491
++ +KDLE+A A +R P+P+ A A Q++ + G G
Sbjct: 241 DIFLKDLEIALDAARALRFPVPIAASAHQVFSMAAGAGDG 280
>UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase
protein; n=2; Burkholderiales|Rep: Putative
dehydrogenase/oxidoreductase protein - Burkholderia
xenovorans (strain LB400)
Length = 300
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/87 (28%), Positives = 39/87 (44%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+A +SG F GG +E+ P+L+ + +F G G+ KL N L
Sbjct: 123 EAELSGSPSLVLARKACFYVGGTDSVYEKCEPLLQAITDNRFFLGAFGTAVSMKLIANYL 182
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGR 262
+ + +A AE MN+G + G P R
Sbjct: 183 VTVNTLAAAEAMNLGTRAGFSPDLLAR 209
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/83 (32%), Positives = 40/83 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP++ + A+ L M G + F++ P+L FH G G+G V KL NN +
Sbjct: 119 DAPLARTPVEAELGRLNTMVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNNFI 178
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
ATAE +G G+ P+
Sbjct: 179 GQAICTATAEAFAVGALAGINPQ 201
>UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Leptosphaeria maculans|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Leptosphaeria
maculans (Blackleg fungus)
Length = 296
Score = 47.2 bits (107), Expect = 3e-04
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
Frame = +3
Query: 246 RSSLDVLNNSSARSWSTEVYCPVPGLVPT--APSSRNYDGGFKNELMVKDLELA--SGMA 413
R+ V+ +S+ +SW + CP+P + PS+ Y GF+ E+MVKDL+L S
Sbjct: 178 RALYAVIQSSTGQSWMCDHVCPIPNVQTQYWVPSNSGYRPGFRTEMMVKDLDLGVRSAAE 237
Query: 414 LGIRSPIPLGAVATQLYRIVQSRGYGQKDFSL 509
+G+ + A+A V R G+ S+
Sbjct: 238 VGVEPTMARAALAVWERAAVDERCRGRDGSSV 269
Score = 41.9 bits (94), Expect = 0.010
Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Frame = +2
Query: 95 PILKVMGA-KQFH-CGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 250
P L ++G +FH +G+G AK+ NN L G +ATAE + +G + GL+P+
Sbjct: 125 PTLHMLGPPSKFHYLSTLGAGLTAKIANNYLSGTILLATAEALALGTRHGLDPR 178
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 46.8 bits (106), Expect = 4e-04
Identities = 26/82 (31%), Positives = 35/82 (42%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG GA + TL M GG + + + H G G+G K NN L
Sbjct: 128 DAPVSGQTSGADSGTLTVMVGGSAKALAYAKSAIDCFAGLIVHVGDSGAGFAVKAVNNTL 187
Query: 182 MGITGMATAECMNMGIKMGLEP 247
I A E +++ G+ P
Sbjct: 188 FAINAWAAVEGLSVLKAHGVNP 209
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 46.4 bits (105), Expect = 5e-04
Identities = 26/70 (37%), Positives = 32/70 (45%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV G A TL F+AGG R P+L+ +G H G G+G KL N L
Sbjct: 119 DAPVLGSRPQADAGTLIFLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQMKLLTNSL 178
Query: 182 MGITGMATAE 211
+ AE
Sbjct: 179 FAVQVATVAE 188
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 46.0 bits (104), Expect = 6e-04
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+ PV+GGV A + + GG +ER ++ M A+ F G IGS V K+ NML
Sbjct: 119 ECPVTGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIKVITNML 178
Query: 182 MGITGMATAECMNMGIKMGLE 244
I +A E + + + GL+
Sbjct: 179 AFIHLVAAGEALMLAKQGGLD 199
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 46.0 bits (104), Expect = 6e-04
Identities = 21/60 (35%), Positives = 33/60 (55%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D+P++G A++ + FM G ++ D + +V G +CG IG GQ AKL NM+
Sbjct: 118 DSPMTGSKNAARDGQILFMIGAKQVDIKDIQFFFEVCGKNAVYCGSIGGGQKAKLALNMI 177
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 46.0 bits (104), Expect = 6e-04
Identities = 21/60 (35%), Positives = 34/60 (56%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+ PV GG + A+ L + GG +E+F+++ LK F+ G++G G +KL NN L
Sbjct: 117 ECPVMGGPVQAEEGVLGGIIGGSEENFKKAEVFLKAFCKDYFYFGEVGMGTKSKLLNNFL 176
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 46.0 bits (104), Expect = 6e-04
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQ---FHCGQIGSGQVAKLTN 172
DAPVSGG A TL MAGG E +L M F G +G+G K+ +
Sbjct: 126 DAPVSGGARKAGEGTLTIMAGGSDAALEEGKFLLTEMADTNKLYFVPGGVGAGSNMKMIH 185
Query: 173 NMLMGITGMATAECMNMGIKMGLEPKFFGRA 265
+ I +A +E M +GL + G+A
Sbjct: 186 QVFAAIHILAASEVMGFAAHLGLNAEEAGKA 216
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 45.6 bits (103), Expect = 8e-04
Identities = 26/83 (31%), Positives = 41/83 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG A+ L +A G++E E+ P+ + F+ G++G KL N L
Sbjct: 120 EAPVSGSSKVAEAGKLLVLAAGKEEIVEQLKPLFAAFSTQTFYYGEVGKAGGVKLMINSL 179
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+GI A E + + G+ PK
Sbjct: 180 LGIFIQAYGEALLFAEQFGI-PK 201
>UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis
Length = 512
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/83 (26%), Positives = 40/83 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+A V G + ++ TL +A G ++ F+ MG F+ G++G+ L ++
Sbjct: 343 EAQVQGSKVQSEEGTLVILAAGDRQLFDDCNSCFGAMGKNTFYLGEVGNASKMNLVLQLM 402
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
G+T AE M + + GL+ K
Sbjct: 403 AGVTLAGLAESMALADRAGLQQK 425
Score = 40.7 bits (91), Expect = 0.024
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +3
Query: 354 DGGFKNEL----MVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
+GGF +L M KDL L+ M+ + PIPL A A ++Y+ + GY + D S
Sbjct: 450 EGGFPTQLPLQHMQKDLRLSLSMSDQLEQPIPLAAAANEIYKHAKRLGYAEHDAS 504
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATL-AFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNM 178
+APVSGG GA++ ++ F+AG D E +L L+ + + F G + KL NN
Sbjct: 114 EAPVSGGPQGARHGSMTVFLAGPAPTDAENAL--LEDISGRVFQMESYGQPALVKLLNNA 171
Query: 179 LMGITGMATAECMNMGIKMGLEPK 250
L ATA +N+ + G+ K
Sbjct: 172 LATYNLAATARMLNLAAEHGVPAK 195
>UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
JLS)
Length = 279
Score = 45.2 bits (102), Expect = 0.001
Identities = 24/83 (28%), Positives = 35/83 (42%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPVSG TL + GG + P+L G +GS KL NN+L
Sbjct: 118 DAPVSGTADDIAAGTLTVLLGGPADAVAAVTPVLAAYADPLVPTGTLGSALALKLINNLL 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
A +G ++G++P+
Sbjct: 178 FAANAQLLAAATELGTQLGVDPE 200
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/80 (28%), Positives = 37/80 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV G + + L + GG ++ ++ + + G GSG AKL NN+
Sbjct: 121 DAPVIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLYAKLVNNLF 180
Query: 182 MGITGMATAECMNMGIKMGL 241
+G + AE + G K G+
Sbjct: 181 LGSYMASLAEAVRFGRKNGI 200
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/84 (34%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +3
Query: 258 DVLNN-SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 434
DVL SSARS ++++ VP ++ S +Y F + M+KD+E+ MA R +
Sbjct: 207 DVLTKYSSARSPTSDL--KVPKMI-----SEDYSVQFSIKNMLKDMEIVDRMASEKRIAL 259
Query: 435 PLGAVATQLYRIVQSRGYGQKDFS 506
P+ ++A QL+R + GYG++D +
Sbjct: 260 PVASLALQLFRYLMDSGYGEEDIA 283
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 44.8 bits (101), Expect = 0.001
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAP+SGG A L + G E E++ P L+++ + G + G GQ K N +
Sbjct: 120 DAPLSGGPKRAGEGDLLIVVGASPEAQEKARPALELLASTLTVVGDKPGDGQALKTVNQL 179
Query: 179 LMGITGMATAECMNMGIKMGLE 244
L G+ A AE + + +GL+
Sbjct: 180 LCGVHIAAAAEALALADALGLD 201
>UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4747-PA - Tribolium castaneum
Length = 267
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/85 (30%), Positives = 39/85 (45%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+A + G A++ +L +A G K F+ K +G F+ G +GS L NM
Sbjct: 97 EAQMQGSKKQAEDGSLIILAAGDKSLFDDCQTCFKAIGKTAFYLGTVGSATKMNLCINMA 156
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+GI AE M + + GL K F
Sbjct: 157 LGIGLAGLAESMVLAERCGLSCKDF 181
Score = 33.1 bits (72), Expect = 4.8
Identities = 13/46 (28%), Positives = 26/46 (56%)
Frame = +3
Query: 372 ELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSL 509
E M KD++L ++ ++ +P+ A A + Y+ + GY + D +L
Sbjct: 215 EYMQKDIKLCLDISNDVKQNLPVAAAANEAYKTARRSGYDEHDVAL 260
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/79 (31%), Positives = 40/79 (50%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLM 184
APVSG V A +A L+ G + F+ P+L + A+Q + G +V KL NM++
Sbjct: 130 APVSGTVSLAASAQLSCFVSGPRPAFDAVQPVLACLTARQSYVGGADEARVIKLMINMMV 189
Query: 185 GITGMATAECMNMGIKMGL 241
++ E + G + GL
Sbjct: 190 FMSTAVIGEGLAFGARAGL 208
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNM 178
DAPV G A+ L + G ++D + P+L+ G++ G G G KL N
Sbjct: 112 DAPVLGTRGPAEQGLLVHLVSGSEDDLAVARPVLEATGSRTVVAGSDAGPGSALKLACNA 171
Query: 179 LMGITGMATAECMNMGIKMGLEPKFF 256
+ AT + + + +G+EP+ F
Sbjct: 172 WIASITAATGQSLGLARLLGVEPRLF 197
>UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase;
n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
6-phosphogluconate dehydrogenase - Uncultured
methanogenic archaeon RC-I
Length = 310
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAK--QFHCGQIGSGQVAKLTNN 175
D SGGV GA+ FM GG +E FE + P+LK + + G GSG AKL +N
Sbjct: 115 DCGTSGGVDGARTGA-CFMVGGSREGFELAEPVLKKLAVDGGVLYTGSPGSGHYAKLVHN 173
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 43.2 bits (97), Expect = 0.004
Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVA-KLTNNML 181
APV G A+ L + GG +E E+ +L++MG K + G+ G +A K++ N +
Sbjct: 116 APVFGRTDVAEAGKLNIVVGGPEEAIEQVKALLEIMGQKTWFFGKDPRGAMAVKISGNFM 175
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGV 304
+ + E + + ++G+EP GR +L+ S L D V
Sbjct: 176 IASAIESMGESVALVKRLGVEP---GRFMELMSSTLFDAPV 213
>UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep:
ENSANGP00000013149 - Anopheles gambiae str. PEST
Length = 581
Score = 43.2 bits (97), Expect = 0.004
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+A + G A+ TL +A G + FE + + F+ G +G+ L M+
Sbjct: 412 EAQIQGSKNQAEEGTLIILASGDRLLFEECQSCFEAISRNSFYLGDVGNATKMNLILQMI 471
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
GIT AE M + + GL+ K
Sbjct: 472 SGITLAGVAEAMALADRAGLQQK 494
Score = 36.7 bits (81), Expect = 0.39
Identities = 16/43 (37%), Positives = 26/43 (60%)
Frame = +3
Query: 378 MVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
M KDL+LA +A G+ +P+ A + ++Y+ + GYG D S
Sbjct: 531 MQKDLKLALSLADGLEQSLPITAASNEVYKHAKRLGYGSHDAS 573
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 43.2 bits (97), Expect = 0.004
Identities = 26/80 (32%), Positives = 36/80 (45%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D P+ A TL +AGG E ER+ P+L MG + + G G G KL NN +
Sbjct: 118 DVPIGRTSDNAITGTLLLLAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVKLINNYM 177
Query: 182 MGITGMATAECMNMGIKMGL 241
+AE + +GL
Sbjct: 178 SIALNALSAEAAVLCEALGL 197
Score = 38.3 bits (85), Expect = 0.13
Identities = 17/48 (35%), Positives = 31/48 (64%)
Frame = +3
Query: 363 FKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 506
F +L KDL +A +A + P+PLGA + ++Y + ++ G G++D+S
Sbjct: 233 FMIDLAHKDLGIALDVANQLHVPMPLGAASREVYNLARAAGRGREDWS 280
>UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Cyanobacteria|Rep: 3-hydroxyacid dehydrogenase -
Anabaena sp. (strain PCC 7120)
Length = 292
Score = 42.7 bits (96), Expect = 0.006
Identities = 22/61 (36%), Positives = 30/61 (49%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APV G + AQ TL M G + +ER L +LK G G +G+ KL N L
Sbjct: 115 EAPVLGSIPEAQAGTLTVMVGAEPQQYERCLNLLKNFGPDPLLIGPVGTASGLKLALNQL 174
Query: 182 M 184
+
Sbjct: 175 I 175
>UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Dinoroseobacter shibae DFL
12|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Dinoroseobacter shibae DFL 12
Length = 289
Score = 42.7 bits (96), Expect = 0.006
Identities = 22/83 (26%), Positives = 39/83 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG AQ+ L + G F+ ++ G G+G AKL NN++
Sbjct: 118 DAPVTGGPKQAQDGALTSLVGCAAAQFDTIASLVGTYSTAIRRFGDAGTGHAAKLLNNLV 177
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
T + ++ ++G++P+
Sbjct: 178 TQGTMVLLSDAFQAAGRLGVDPR 200
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 42.3 bits (95), Expect = 0.008
Identities = 25/85 (29%), Positives = 36/85 (42%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+S A TL M G F R P+++ + H G G G KL NN +
Sbjct: 125 DAPLSRTPKEAWEGTLDAMVGAPDAVFARVKPVIETWAGRIVHIGDTGDGHRMKLLNNFI 184
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+E + + K+G+ P F
Sbjct: 185 SLGYAAIYSEALALAEKVGISPPRF 209
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/85 (27%), Positives = 37/85 (43%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PV G A L + GG +E + L +G + G G+G KL N+
Sbjct: 126 DTPVVGSKDLASKGELIILVGGSQEVLRKHEKFLNKLGKSVIYLGADGNGHKMKLAINLH 185
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
+G+ + +E + K+G + K F
Sbjct: 186 LGLLAESFSEALVFSQKLGFDAKTF 210
>UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Candidatus Methanoregula boonei
6A8|Rep: 6-phosphogluconate dehydrogenase, NAD-binding -
Methanoregula boonei (strain 6A8)
Length = 288
Score = 41.1 bits (92), Expect = 0.018
Identities = 21/81 (25%), Positives = 39/81 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+ PV G V+ A L + G + +E P+L +G+ ++ G+ KL NN++
Sbjct: 118 ECPVLGSVVPASQGKLTVLVSGDEGTYEVVKPLLSRIGSTLYYLGEPALATKMKLINNLV 177
Query: 182 MGITGMATAECMNMGIKMGLE 244
+G AE + +G G++
Sbjct: 178 LGSFMATCAEAVALGEAAGID 198
Score = 35.9 bits (79), Expect = 0.68
Identities = 13/56 (23%), Positives = 32/56 (57%)
Frame = +3
Query: 342 SRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSL 509
+R + F + L+ KDL + ++ P+ +G+ +++ + +S+G ++DFS+
Sbjct: 225 NREFSPHFSSALIYKDLHYLQDLCRTLKKPLFVGSTVKEVFALARSKGIDEQDFSV 280
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 40.7 bits (91), Expect = 0.024
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQ-IGSGQVAKLTNNML 181
APV G A+ TL +A G +++ P+L +G K F G+ + + KL N+L
Sbjct: 137 APVLGNPDLARARTLFILAAGPDAAMQKARPLLDRLGQKLFVIGEDAAAANLVKLAGNVL 196
Query: 182 MGITGMATAECMNMGIKMGLEPK 250
+T + E + + K G++P+
Sbjct: 197 TALTLQSMGEVLALLRKSGIDPR 219
>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
Actinobacteria (class)|Rep: Phosphogluconate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 40.3 bits (90), Expect = 0.031
Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPI---LKVMGAKQ---FHCGQIGSGQVAK 163
D VSGGV G ++ M GG D ER+LPI L+ G + H G +G+G AK
Sbjct: 108 DCGVSGGVWGLEDG-YGMMVGGSDADVERALPIFDALRPEGERADGFVHAGPVGAGHYAK 166
Query: 164 LTNN 175
+ +N
Sbjct: 167 MIHN 170
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 40.3 bits (90), Expect = 0.031
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVA---KLTNN 175
APVSG A+ ATL G + ER+ P+L A+ H +G G+ A KL N
Sbjct: 114 APVSGSTATAEAATLTLFCSGPETALERARPLLATF-ARTIHA--VGPGEEARFLKLAIN 170
Query: 176 MLMGITGMATAECMNMGIKMGL 241
+G T AE + + + G+
Sbjct: 171 HFVGSTAQVAAEALTLARRGGV 192
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 40.3 bits (90), Expect = 0.031
Identities = 24/80 (30%), Positives = 33/80 (41%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV+GG GA TL + G ++ + +L G G+G V KL L
Sbjct: 120 DAPVTGGAEGAAAGTLTMLLGIDEQILTKFTSMLNAFTKNAIRMGPSGAGYVTKLAQLHL 179
Query: 182 MGITGMATAECMNMGIKMGL 241
+ E + MG K L
Sbjct: 180 NYLVAQGIGEALMMGAKAEL 199
>UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 319
Score = 40.3 bits (90), Expect = 0.031
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQV-AKLTNNML 181
APVSGG A L F+ GG +E + VMGAK++ G + AKL ++
Sbjct: 144 APVSGGWRDAAKGELLFLGGGDARAYEDGARFMDVMGAKRWLVGDSPTHAARAKLMLQIM 203
Query: 182 MGITGMATAECMNMGIKMGLE 244
MG A E + + GL+
Sbjct: 204 MGNVVGALGEMHALSERAGLD 224
>UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase related
protein; n=10; Synechococcus|Rep: 3-hydroxyisobutyrate
dehydrogenase related protein - Synechococcus sp.
(strain WH7803)
Length = 288
Score = 39.9 bits (89), Expect = 0.041
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APV G A TL MAGG + F++ +LK + + G +G+G AKL N L
Sbjct: 113 EAPVLGSRPEALAGTLLVMAGGDQGVFDQQYALLKHLALEPKRMGAVGTGAAAKLALNQL 172
Query: 182 M 184
+
Sbjct: 173 I 173
>UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7;
Firmicutes|Rep: 6-phosphogluconate dehydrogenase -
Bacillus halodurans
Length = 298
Score = 39.5 bits (88), Expect = 0.055
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQ--FHCGQIGSGQVAKLTNN 175
DA SGG+ GA+ M GG KE E P+LK + + + G +GSG K+ +N
Sbjct: 117 DAGTSGGIDGAREGA-CLMVGGTKEVVESLAPLLKEIAVEDGYLYTGPVGSGHFLKMIHN 175
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 39.5 bits (88), Expect = 0.055
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHC---GQIGSGQVAKLTN 172
DAPV G A+NA L +A G + D + P+ +G + G G+G KL
Sbjct: 123 DAPVQGSRQPAENAQLVVLAAGPESDRAQVQPLFDAIGRRTLWVADDGSTGAGSRLKLAL 182
Query: 173 NMLMGITGMATAECMNMGIKMGLEPK 250
N A AE + + +G +P+
Sbjct: 183 NHYAFTLTHAIAESLKLAGALGADPR 208
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 39.5 bits (88), Expect = 0.055
Identities = 24/81 (29%), Positives = 33/81 (40%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D PV+GG GA TL + G + D +L A G GQ AKL N +
Sbjct: 121 DCPVTGGESGAIAGTLTAIVGATENDIAPVRDVLSTFAANICCFDGAGKGQAAKLANQVS 180
Query: 182 MGITGMATAECMNMGIKMGLE 244
+ + A+ M GL+
Sbjct: 181 LAACMVGMADAMAFAELSGLD 201
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 39.1 bits (87), Expect = 0.072
Identities = 25/79 (31%), Positives = 31/79 (39%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAPV G A N L +AGG R + G H G IG K N++
Sbjct: 119 DAPVWGTKEHAANGLLTILAGGDPSLVGRCRELFSFFGLNIIHVGSIGDATRMKFVVNLV 178
Query: 182 MGITGMATAECMNMGIKMG 238
A AE + G K+G
Sbjct: 179 QAELMQALAESIVFGEKLG 197
>UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni
ACN14a|Rep: Putative reductase - Frankia alni (strain
ACN14a)
Length = 262
Score = 39.1 bits (87), Expect = 0.072
Identities = 21/80 (26%), Positives = 32/80 (40%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+SG L + GG +R P+L + G +GS KL NN+
Sbjct: 107 DAPISGTSATILAGRLTVLIGGAAAAADRVEPLLAAYASTIVRTGDVGSATTVKLINNLT 166
Query: 182 MGITGMATAECMNMGIKMGL 241
+ +G K+G+
Sbjct: 167 FAAHVQTAVAAVQLGEKLGI 186
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 39.1 bits (87), Expect = 0.072
Identities = 22/82 (26%), Positives = 38/82 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
D V+ G A + +A + GG + E + P+L + HCG +G+G V K+ N++
Sbjct: 123 DCGVTPGDRAADHGMVAIV-GGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIARNVV 181
Query: 182 MGITGMATAECMNMGIKMGLEP 247
+ A E + G+ P
Sbjct: 182 TYGSWRAVFEASALARAAGVNP 203
>UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase; n=1; Lactobacillus casei
ATCC 334|Rep: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase - Lactobacillus casei
(strain ATCC 334)
Length = 285
Score = 39.1 bits (87), Expect = 0.072
Identities = 22/59 (37%), Positives = 31/59 (52%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNM 178
D P+ GGV A+ A L +A G K+ PILK G ++ G+ G+G KL N+
Sbjct: 118 DVPMIGGVKYAREAGLVLIAAGDKQAVADVTPILKTFGTVKY-VGEQGNGAKLKLITNV 175
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 39.1 bits (87), Expect = 0.072
Identities = 22/84 (26%), Positives = 41/84 (48%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLM 184
APVSG + L+ + G +E +ER +L +G + G+ ++AK+ +N+++
Sbjct: 128 APVSGNGKVVRAGGLSLVVSGPEETYERVAHLLDHLGKGATYVGEGELARLAKICHNVML 187
Query: 185 GITGMATAECMNMGIKMGLEPKFF 256
G+ AE + K G+ F
Sbjct: 188 GVVTQCLAEITVLAEKGGMSRAAF 211
>UniRef50_A1C8I6 Cluster: NAD binding NADP oxidoreductase coenzyme
F420-dependent, putative; n=1; Aspergillus clavatus|Rep:
NAD binding NADP oxidoreductase coenzyme F420-dependent,
putative - Aspergillus clavatus
Length = 292
Score = 38.7 bits (86), Expect = 0.096
Identities = 24/87 (27%), Positives = 38/87 (43%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+ PVSG + A+ L M G + ++ I++ M +CG IG G K N+
Sbjct: 113 EMPVSGSKVPAEQGQLIGMLAGDFDTAQQVKSIVEPMTKDAIYCGNIGMGLKTKYAVNVF 172
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGR 262
+ AE M + GL+ FG+
Sbjct: 173 LITMTAGLAESMALAKAQGLDIAAFGQ 199
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 38.3 bits (85), Expect = 0.13
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCG-QIGSGQVAKLTNNML 181
APV G A+ A L + G E +++ P+L ++ + F G + + AK++ N L
Sbjct: 118 APVLGRPDAAEKAELRIITAGPAEAKKKAEPLLNILSQQVFDTGEETKTANAAKISVNFL 177
Query: 182 MGITGMATAECMNMGIKMGLEPK-FFGRAEQLIGS 283
+ A +E M K GLE K F A L GS
Sbjct: 178 LVSMLEALSESFLMMEKYGLEQKQFLEIAGALFGS 212
>UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=3; Rhodobacteraceae|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 292
Score = 38.3 bits (85), Expect = 0.13
Identities = 23/85 (27%), Positives = 33/85 (38%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP++ A TL + GG + ER P+L H G + G KL +N +
Sbjct: 119 DAPMTRTARHAHEGTLNLLVGGATDTLERVRPVLSTFTEDVAHVGPLSHGHRLKLLHNYV 178
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
AE G++P F
Sbjct: 179 SVGFMTLLAEAAAQSADAGVDPAVF 203
>UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Mycobacterium sp.
(strain JLS)
Length = 297
Score = 38.3 bits (85), Expect = 0.13
Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 6/64 (9%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMG-----AKQF-HCGQIGSGQVAK 163
DA VSGGV G M GG D ER +PI + A F H G +G+G AK
Sbjct: 108 DAGVSGGVWGLAEG-YGLMVGGDDADIERVMPIFDTLRPPGDRADGFVHAGPVGAGHFAK 166
Query: 164 LTNN 175
+ +N
Sbjct: 167 MVHN 170
>UniRef50_Q5LQS2 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Alphaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Silicibacter pomeroyi
Length = 303
Score = 37.9 bits (84), Expect = 0.17
Identities = 22/85 (25%), Positives = 37/85 (43%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+ A++ TL M G + + P++ G +G+G KL N L
Sbjct: 121 DAPLGRTPKEAEDGTLDAMVGCDEALMKTITPVIDCWAGTITRIGPVGAGHKMKLLMNFL 180
Query: 182 MGITGMATAECMNMGIKMGLEPKFF 256
G +E + +G ++G+ P F
Sbjct: 181 GGAYAALYSEAVVLGARVGISPHTF 205
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 37.5 bits (83), Expect = 0.22
Identities = 17/63 (26%), Positives = 34/63 (53%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLM 184
APV+GG ++ LA G ++ FE + +L+V+ + G + ++ K+ +N+L+
Sbjct: 127 APVAGGPPVIESGGLAMAVSGDRQAFEHAADVLRVVAPNLIYVGPGDTSRLVKICHNLLV 186
Query: 185 GIT 193
T
Sbjct: 187 AAT 189
>UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 293
Score = 37.1 bits (82), Expect = 0.29
Identities = 23/80 (28%), Positives = 31/80 (38%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
DAP+ T A GG + IL+ + HCG GSG +L +
Sbjct: 114 DAPLHTENTATAPETSAIFFGGPSSVLASTREILENVCPTIIHCGDAGSGHAMRLVVAAI 173
Query: 182 MGITGMATAECMNMGIKMGL 241
+ T EC MG + GL
Sbjct: 174 AACNRLITYECAAMGARNGL 193
>UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyacid dehydrogenase -
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG
1402/1)(Anacystis nidulans)
Length = 296
Score = 36.3 bits (80), Expect = 0.51
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APV G + A+N TL M G FE+ +L + + G IG+ KL N L
Sbjct: 123 EAPVLGSLPEARNGTLIVMVGAEPAVFEQWRSLLCHLSPEPEWIGPIGTAATLKLALNQL 182
Query: 182 MG 187
+G
Sbjct: 183 IG 184
>UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Rhodobacter sphaeroides|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Rhodobacter sphaeroides (strain ATCC 17029 / ATH
2.4.9)
Length = 288
Score = 36.3 bits (80), Expect = 0.51
Identities = 20/70 (28%), Positives = 32/70 (45%)
Frame = +2
Query: 8 PVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNMLMG 187
PV G V A L AGG E +R+ P+L+ + + H G +G+ KL N+ +
Sbjct: 116 PVGGTVAPALKGQLLGFAGGPAETLDRARPVLERLCRRVEHLGPVGAAARMKLAVNLPLA 175
Query: 188 ITGMATAECM 217
+ E +
Sbjct: 176 LYWQTLGESL 185
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 36.3 bits (80), Expect = 0.51
Identities = 27/104 (25%), Positives = 48/104 (46%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG + + L +A G + +E + MG F G++G+ L NM+
Sbjct: 384 EAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQTMGKTSFFLGEVGNAAKMMLIVNMV 443
Query: 182 MGITGMATAECMNMGIKMGLEPKFFGRAEQLIGSLLVDRGVLSS 313
G AE + + + GR++Q + +L ++G L+S
Sbjct: 444 QGSFMATIAEGLTLA-------QVTGRSQQTLLDIL-NQGQLAS 479
Score = 32.3 bits (70), Expect = 8.3
Identities = 16/58 (27%), Positives = 30/58 (51%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSLSSSY 521
N+ F + + KDL LA + + P P+ A A ++Y+ +++ Q D +S+ Y
Sbjct: 493 NFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYK--RAKALDQSDNDMSAVY 548
>UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;
n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
Bos taurus
Length = 351
Score = 35.9 bits (79), Expect = 0.68
Identities = 21/68 (30%), Positives = 33/68 (48%)
Frame = +2
Query: 2 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGSGQVAKLTNNML 181
+APVSG + + L +A G + +E + MG F G++G+ L NM+
Sbjct: 182 EAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMV 241
Query: 182 MGITGMAT 205
G + MAT
Sbjct: 242 QG-SFMAT 248
Score = 32.3 bits (70), Expect = 8.3
Identities = 16/58 (27%), Positives = 30/58 (51%)
Frame = +3
Query: 348 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSLSSSY 521
N+ F + + KDL LA + + P P+ A A ++Y+ +++ Q D +S+ Y
Sbjct: 291 NFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYK--RAKALDQSDNDMSAVY 346
>UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 307
Score = 35.9 bits (79), Expect = 0.68
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +2
Query: 5 APVSGGVMGAQNATLAFMAGGRKEDFERSLPILKVMGAKQFHCGQIGS--GQVAKLTNNM 178
APV G A+ TL +A G ++ E LP+L+ +G+ F G+ S + L N
Sbjct: 129 APVFGRPDRAEAGTLTIVAAGPQKTLESLLPLLEHLGSPVFCVGEDPSLANHIKVLGNFT 188
Query: 179 LMGITGMATAECMNMGIKMGLEP 247
L G+ AE +++ ++G+ P
Sbjct: 189 LAGLL-ETLAESLSLARRVGVSP 210
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 628,774,622
Number of Sequences: 1657284
Number of extensions: 13764642
Number of successful extensions: 43014
Number of sequences better than 10.0: 278
Number of HSP's better than 10.0 without gapping: 40787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42891
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 39154548218
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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