BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= mg--0048 (727 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5; Fungi/Me... 137 3e-31 UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1; Bifidoba... 132 1e-29 UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1; ... 120 5e-26 UniRef50_A6MJX0 Cluster: 2-hydroxyacyl-CoA lyase 1-like protein;... 117 3e-25 UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1; ... 116 8e-25 UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40; Eukary... 115 1e-24 UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;... 107 4e-22 UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, wh... 105 8e-22 UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3; ... 103 4e-21 UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13; Magnoli... 91 2e-17 UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16 UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3; S... 86 1e-15 UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Re... 82 2e-14 UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60; Bacteri... 80 6e-14 UniRef50_UPI000150A350 Cluster: Thiamine pyrophosphate enzyme, c... 77 4e-13 UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central ... 76 8e-13 UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate synthase)-... 65 2e-09 UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12; M... 61 3e-08 UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3; ... 58 2e-07 UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2; Rhodo... 58 2e-07 UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n... 58 3e-07 UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 55 2e-06 UniRef50_A2SP25 Cluster: Acetolactate synthase-like TPP-requirin... 54 3e-06 UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 54 5e-06 UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:... 52 1e-05 UniRef50_A4IL27 Cluster: Acetolactate synthase; n=1; Geobacillus... 52 1e-05 UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2; Proteobact... 51 3e-05 UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 51 3e-05 UniRef50_Q607C4 Cluster: Acetolactate synthase; n=1; Methylococc... 50 4e-05 UniRef50_A1ICC6 Cluster: Putative TPP-requiring enzyme; n=1; Can... 50 6e-05 UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain pr... 50 8e-05 UniRef50_Q01Q83 Cluster: Thiamine pyrophosphate enzyme domain pr... 48 2e-04 UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central ... 48 2e-04 UniRef50_A6PTN2 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 48 3e-04 UniRef50_A1HPN8 Cluster: Acetolactate synthase, large subunit, b... 47 4e-04 UniRef50_Q41EN3 Cluster: Pyruvate decarboxylase; n=1; Exiguobact... 46 7e-04 UniRef50_A5TSK5 Cluster: Acetolactate synthase; n=1; Fusobacteri... 46 0.001 UniRef50_P42463 Cluster: Acetolactate synthase large subunit; n=... 45 0.002 UniRef50_P40811 Cluster: Acetolactate synthase isozyme 3 large s... 45 0.002 UniRef50_P51853 Cluster: Benzaldehyde lyase; n=3; Pseudomonas fl... 45 0.002 UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain pr... 44 0.003 UniRef50_Q04789 Cluster: Acetolactate synthase; n=69; Bacteria|R... 44 0.003 UniRef50_O08353 Cluster: Probable acetolactate synthase large su... 44 0.003 UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requirin... 44 0.004 UniRef50_Q5LQV0 Cluster: Benzaldehyde lyase, putative; n=1; Sili... 44 0.005 UniRef50_Q5LKS2 Cluster: Sulphoacetaldehyde acetyltransferase, p... 44 0.005 UniRef50_Q88Y01 Cluster: Acetolactate synthase; n=25; Bacilli|Re... 43 0.007 UniRef50_Q7WPE1 Cluster: Thiamine pyrophosphate enzyme; n=2; Pro... 43 0.007 UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1; uncult... 43 0.007 UniRef50_Q7U5G1 Cluster: Acetolactate synthase large subunit; n=... 43 0.009 UniRef50_A3X9K6 Cluster: Acetolactate synthase-like TPP-requirin... 42 0.012 UniRef50_A3DID9 Cluster: Acetolactate synthase; n=3; Clostridium... 42 0.012 UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=... 42 0.016 UniRef50_Q9WZ18 Cluster: Acetolactate synthase; n=7; cellular or... 42 0.021 UniRef50_Q2LXP1 Cluster: Acetolactate synthase large subunit; n=... 42 0.021 UniRef50_A5GC69 Cluster: Acetolactate synthase; n=3; cellular or... 42 0.021 UniRef50_Q9K659 Cluster: Acetolactate synthase large subunit; n=... 41 0.027 UniRef50_Q97EE4 Cluster: Acetolactate synthase; n=10; Clostridia... 41 0.027 UniRef50_Q7W2M5 Cluster: Acetolactate synthase large subunit; n=... 41 0.027 UniRef50_A6BEJ7 Cluster: Acetolactate synthase; n=3; Clostridial... 41 0.027 UniRef50_O28264 Cluster: Acetolactate synthase, large subunit; n... 41 0.027 UniRef50_Q89QL7 Cluster: Bll3107 protein; n=2; Proteobacteria|Re... 41 0.036 UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme... 41 0.036 UniRef50_O28180 Cluster: Acetolactate synthase, large subunit; n... 41 0.036 UniRef50_Q5YN72 Cluster: Putative acetolactate synthase large su... 40 0.047 UniRef50_Q3JBM9 Cluster: Acetolactate synthase large subunit; n=... 40 0.047 UniRef50_Q0FGP6 Cluster: Acetolactate synthase II large subunit;... 40 0.047 UniRef50_Q025T6 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 40 0.063 UniRef50_A0WA20 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 40 0.063 UniRef50_A5K231 Cluster: Bi-functional enzyme: long-chain fatty-... 40 0.063 UniRef50_Q0CI52 Cluster: Putative uncharacterized protein; n=1; ... 40 0.063 UniRef50_A4AC84 Cluster: Acetolactate synthase; n=2; cellular or... 40 0.083 UniRef50_A1SCQ1 Cluster: Thiamine pyrophosphate enzyme domain pr... 40 0.083 UniRef50_Q7WCV8 Cluster: Putative acetolactate synthase large su... 39 0.11 UniRef50_Q2S0N1 Cluster: Acetolactate synthase, large subunit, b... 39 0.11 UniRef50_Q18S72 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 39 0.11 UniRef50_A2QFR5 Cluster: Acetolactate synthase; n=3; Aspergillus... 39 0.11 UniRef50_Q8EP38 Cluster: Acetolactate synthase large subunit; n=... 39 0.14 UniRef50_Q2AIK5 Cluster: Thiamine pyrophosphate enzyme, C-termin... 39 0.14 UniRef50_Q6LF61 Cluster: Putative bi-functional enzyme: long-cha... 39 0.14 UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular o... 38 0.19 UniRef50_Q3XZD0 Cluster: Pyruvate decarboxylase; n=3; Lactobacil... 38 0.19 UniRef50_A1WXE6 Cluster: Acetolactate synthase; n=6; Proteobacte... 38 0.19 UniRef50_A0W3U9 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 38 0.19 UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzyme... 38 0.19 UniRef50_Q11NN4 Cluster: Acetolactate synthase, large subunit; n... 38 0.25 UniRef50_A1R2T4 Cluster: Putative acetolactate synthase, large s... 38 0.25 UniRef50_Q8U2A4 Cluster: Acetolactate synthase; n=4; cellular or... 38 0.25 UniRef50_Q2NI87 Cluster: Acetolactate synthase; n=2; Methanospha... 38 0.25 UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large s... 38 0.25 UniRef50_Q1IPP8 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 38 0.33 UniRef50_P00892 Cluster: Acetolactate synthase isozyme 2 large s... 38 0.33 UniRef50_Q988P8 Cluster: Acetolactate synthase, large subunit; n... 37 0.44 UniRef50_Q8F341 Cluster: Acetolactate synthase large subunit; n=... 37 0.44 UniRef50_Q64QU8 Cluster: Pyruvate dehydrogenase; n=6; Bacteroide... 37 0.44 UniRef50_Q70I04 Cluster: Putative acetolactate synthase; n=1; St... 37 0.44 UniRef50_Q1M4Y3 Cluster: Putative thiamine pyrophosphate requiri... 37 0.44 UniRef50_A6LX01 Cluster: Thiamine pyrophosphate protein, central... 37 0.44 UniRef50_A6G7M7 Cluster: Acetolactate synthase large subunit; n=... 37 0.44 UniRef50_Q84H41 Cluster: Sulfoacetaldehyde acetyltransferase; n=... 37 0.44 UniRef50_Q8TR30 Cluster: Acetolactate synthase, large subunit; n... 37 0.58 UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large s... 36 0.77 UniRef50_Q13H77 Cluster: Putative pyruvate decarboxylase; n=1; B... 36 0.77 UniRef50_A6NPM8 Cluster: Acetolactate synthase; n=2; Bacteria|Re... 36 0.77 UniRef50_A3GGL8 Cluster: Pyruvate decarboxylase; n=5; Saccharomy... 36 0.77 UniRef50_P37063 Cluster: Pyruvate oxidase; n=2; Lactobacillus pl... 36 0.77 UniRef50_Q9RU76 Cluster: Acetolactate synthase; n=3; Bacteria|Re... 36 1.0 UniRef50_Q8ELJ0 Cluster: Acetolactate synthase large subunit; n=... 36 1.0 UniRef50_A6G882 Cluster: Acetolactate synthase large subunit; n=... 36 1.0 UniRef50_A5ZRI3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0 UniRef50_A0KE44 Cluster: Thiamine pyrophosphate enzyme domain pr... 36 1.0 UniRef50_O01535 Cluster: Seven tm receptor protein 136; n=2; Cae... 36 1.0 UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5; Lactobacillaceae... 36 1.3 UniRef50_Q39P46 Cluster: Acetolactate synthase, large subunit; n... 36 1.3 UniRef50_Q04D18 Cluster: Thiamine pyrophosphate-requiring enzyme... 36 1.3 UniRef50_A6DLM5 Cluster: Acetolactate synthase; n=1; Lentisphaer... 36 1.3 UniRef50_Q7RCT1 Cluster: Peroxisomal-coenzyme a synthetase; n=5;... 36 1.3 UniRef50_P06672 Cluster: Pyruvate decarboxylase; n=8; cellular o... 36 1.3 UniRef50_P26263 Cluster: Pyruvate decarboxylase isozyme 3; n=26;... 36 1.3 UniRef50_Q88YC4 Cluster: Pyruvate oxidase; n=5; Lactobacillales|... 35 1.8 UniRef50_Q3A0L4 Cluster: Pyruvate decarboxylase; n=3; Bacteria|R... 35 1.8 UniRef50_Q6JHM8 Cluster: Acetolactate synthase; n=1; Saccharopol... 35 1.8 UniRef50_A6X6D0 Cluster: Thiamine pyrophosphate protein central ... 35 1.8 UniRef50_A5V6Y6 Cluster: Thiamine pyrophosphate enzyme domain pr... 35 1.8 UniRef50_A5MZ19 Cluster: Acetolactate synthase; n=1; Clostridium... 35 1.8 UniRef50_Q60A74 Cluster: Decarboxylase, thiamine pyrophosphate e... 35 2.4 UniRef50_O68497 Cluster: Catabolic acetolactate synthase; n=11; ... 35 2.4 UniRef50_Q28MM5 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 35 2.4 UniRef50_Q1YQE9 Cluster: Acetolactate synthase, large subunit; n... 35 2.4 UniRef50_Q1AVS4 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 35 2.4 UniRef50_Q2U387 Cluster: Thiamine pyrophosphate-requiring enzyme... 35 2.4 UniRef50_Q8TPF5 Cluster: Acetolactate synthase; n=12; cellular o... 35 2.4 UniRef50_Q6L042 Cluster: Acetolactate synthase; n=6; Archaea|Rep... 35 2.4 UniRef50_P06169 Cluster: Pyruvate decarboxylase isozyme 1; n=3; ... 35 2.4 UniRef50_P0AEP8 Cluster: Glyoxylate carboligase; n=131; Bacteria... 35 2.4 UniRef50_Q89D42 Cluster: MdlC protein; n=3; Bradyrhizobium|Rep: ... 34 3.1 UniRef50_Q2W979 Cluster: Thiamine pyrophosphate-requiring enzyme... 34 3.1 UniRef50_Q9X5G0 Cluster: Acetolactate synthase; n=57; Bacteria|R... 34 3.1 UniRef50_A7QYX6 Cluster: Chromosome chr16 scaffold_258, whole ge... 34 3.1 UniRef50_Q28XE8 Cluster: GA18626-PA; n=2; Endopterygota|Rep: GA1... 34 3.1 UniRef50_Q7D5H1 Cluster: Acetolactate synthase, large subunit, p... 34 4.1 UniRef50_Q4EB17 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1 UniRef50_A5TVK4 Cluster: Possible thiamine pyrophosphate enzyme;... 34 4.1 UniRef50_Q58077 Cluster: Uncharacterized protein MJ0663; n=6; Me... 34 4.1 UniRef50_UPI00006CDE0D Cluster: hypothetical protein TTHERM_0029... 33 5.4 UniRef50_UPI00005F9B31 Cluster: COG0022: Pyruvate/2-oxoglutarate... 33 5.4 UniRef50_Q7NIX5 Cluster: Indole-3-pyruvate decarboxylase; n=3; B... 33 5.4 UniRef50_Q4K6F7 Cluster: Acetolactate synthase II, large subunit... 33 5.4 UniRef50_Q3IXG3 Cluster: Thiamine pyrophosphate-requiring enzyme... 33 5.4 UniRef50_Q1ILZ1 Cluster: Acetolactate synthase; n=5; cellular or... 33 5.4 UniRef50_Q759M2 Cluster: ADR254Wp; n=1; Eremothecium gossypii|Re... 33 5.4 UniRef50_Q2HA42 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4 UniRef50_Q0CB10 Cluster: Predicted protein; n=1; Aspergillus ter... 33 5.4 UniRef50_P51852 Cluster: Indole-3-pyruvate decarboxylase; n=16; ... 33 5.4 UniRef50_Q8G7H0 Cluster: Acetolactate synthase; n=2; Bifidobacte... 33 7.2 UniRef50_Q5LKG3 Cluster: Acetolactate synthase, large subunit, p... 33 7.2 UniRef50_Q3M5M2 Cluster: Thiamine pyrophosphate enzyme; n=1; Ana... 33 7.2 UniRef50_Q0SHU3 Cluster: Pyruvate dehydrogenase; n=15; Bacteria|... 33 7.2 UniRef50_Q186C0 Cluster: Acetolactate synthase; n=2; Clostridium... 33 7.2 UniRef50_Q036H9 Cluster: Pyruvate oxidase; n=1; Lactobacillus ca... 33 7.2 UniRef50_A6CD43 Cluster: Pyruvate decarboxylase; n=1; Planctomyc... 33 7.2 UniRef50_A0PNI1 Cluster: Acetolactate synthase (Large subunit) I... 33 7.2 UniRef50_Q9SLK4 Cluster: F20D21.12 protein; n=3; Arabidopsis tha... 33 7.2 UniRef50_Q7QY44 Cluster: GLP_10_3431_5173; n=1; Giardia lamblia ... 33 7.2 UniRef50_Q4N2S4 Cluster: Zinc finger protein, putative; n=2; The... 33 7.2 UniRef50_A0E9R8 Cluster: Chromosome undetermined scaffold_85, wh... 33 7.2 UniRef50_A7TRE3 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_Q9Q8F9 Cluster: M144R; n=3; Leporipoxvirus|Rep: M144R -... 33 9.5 UniRef50_Q88S56 Cluster: Pyruvate oxidase; n=2; Lactobacillus pl... 33 9.5 UniRef50_Q5FHQ7 Cluster: Pyruvate oxidase; n=12; Lactobacillacea... 33 9.5 UniRef50_P96591 Cluster: YdaP protein; n=11; Bacillaceae|Rep: Yd... 33 9.5 UniRef50_Q26HU8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5 UniRef50_Q1N3D1 Cluster: Pyruvate oxidase; n=2; Gammaproteobacte... 33 9.5 UniRef50_Q1ARE6 Cluster: Acetolactate synthase; n=4; Bacteria|Re... 33 9.5 UniRef50_A6QC71 Cluster: Acetolactate synthase, large subunit; n... 33 9.5 UniRef50_A6CP74 Cluster: Acetolactate synthase large subunit; n=... 33 9.5 UniRef50_A0VEM6 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 33 9.5 UniRef50_A0IIS8 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 33 9.5 UniRef50_A2ESQ8 Cluster: Surface antigen BspA-like; n=3; Trichom... 33 9.5 UniRef50_Q8ZTD9 Cluster: Acetolactate synthase; n=5; Thermoprote... 33 9.5 UniRef50_Q8PT77 Cluster: Acetolactate synthase; n=4; cellular or... 33 9.5 UniRef50_P20906 Cluster: Benzoylformate decarboxylase; n=14; Bac... 33 9.5 >UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5; Fungi/Metazoa group|Rep: Oxalyl-CoA decarboxylase - Schizosaccharomyces pombe (Fission yeast) Length = 568 Score = 137 bits (331), Expect = 3e-31 Identities = 84/246 (34%), Positives = 127/246 (51%), Gaps = 7/246 (2%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E+T +PFLP+PMGKG++ + VS+AR+ AL ADV+LL GAR+NW+ +G PP+++P Sbjct: 227 EHTGIPFLPSPMGKGLLPESHPLNVSSARSAALRNADVVLLAGARLNWIFQYGLPPKWSP 286 Query: 189 DVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVGGRD*NRT 368 + K IQ++ + E N+ + + +T R N T Sbjct: 287 NAKFIQIDTNAETLGNNAADLDLAIWADVGLTIDCLFKLVQTWKYSVGISTPYLRTLNET 346 Query: 369 KSKHRICRGSSKQHCSTTELLHC-------FQNSSTRHSKRFNHCQRRSEYHGYGRGLLL 527 +SK+ S++ ++ + Q+ S + + + GR LL Sbjct: 347 RSKNEKKALESRKSSIPLQMNYALYVVNEELQSLSLKSKRNITWVSEGANTMDRGRQLLE 406 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFR 707 HPR RLDAGT TMGVG G+AIA+A +++ VEGDSAFGFS ME+ET R Sbjct: 407 VTHPRGRLDAGTMSTMGVGMGYAIASAF----AHSSDKIVVVEGDSAFGFSAMELETAIR 462 Query: 708 YKLPVI 725 +L ++ Sbjct: 463 NQLDLL 468 >UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1; Bifidobacterium animalis|Rep: Oxalyl-CoA decarboxylase - Bifidobacterium animalis subsp. lactis (Bifidobacterium lactis) Length = 590 Score = 132 bits (318), Expect = 1e-29 Identities = 79/239 (33%), Positives = 116/239 (48%), Gaps = 1/239 (0%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E T +PF P M KGV+ D+ +C ++ R AL ADV+LL+GAR+NWML+FG+ + P Sbjct: 244 EKTDMPFQPMSMAKGVIPDDDPHCTASCRGLALRTADVVLLVGARLNWMLNFGEGKEWNP 303 Query: 189 DVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLK-TTVGGRD*NR 365 +VK IQ++I P E N++ G K + + + D + Sbjct: 304 NVKFIQIDIDPNEIENARSIACPVVGDIKSAMQMINAGLEKTPVKASAQWLDMLKADAEK 363 Query: 366 TKSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLLNNHPRH 545 +K S+ + L + +H + + R ++ PRH Sbjct: 364 NDAKFAARVNSNTVPMGHYDALGAIKKVYDQHKDMILTNEGANTLDDC-RNIIDIYQPRH 422 Query: 546 RLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 RLD GT+G MG G++I AA+ A GK V+ V GDS FGF GME+E RY LP+ Sbjct: 423 RLDCGTWGVMGCAVGYSIGAAV-----ATGKPVLYVGGDSGFGFDGMEVEVACRYNLPI 476 >UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 571 Score = 120 bits (288), Expect = 5e-26 Identities = 80/241 (33%), Positives = 124/241 (51%), Gaps = 6/241 (2%) Frame = +3 Query: 21 LPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKI 200 LPF+ TPM +G+V D S+ V++AR+ AL A+++LL+G ++NW+LHFG ++ + Sbjct: 239 LPFITTPMARGIVPDSSKLNVASARSLALKNAEIVLLIGTKLNWILHFGSSSKWNENTLF 298 Query: 201 IQVEISPEE--FHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVGGRD*NRTKS 374 IQ++ SP +NSK E K + + + G + + K Sbjct: 299 IQIDNSPSNLGLNNSKGLEYSLFGNISVTLDKLSRSLIKFNKNKQWRYQ-GPTENIKIKI 357 Query: 375 K-HRICRGSSKQHCSTTELLHCFQNSSTR---HSKRFNHCQRRSEYHGYGRGLLLNNHPR 542 K + I + + ST++L + S R + + + R ++P+ Sbjct: 358 KENEINLKKKESNHSTSQLNYNEVYGSLRKILNDRETIIVMEGANTMDIARISFKTDYPQ 417 Query: 543 HRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 HRLD G TMGVG G+AI+A + P K V+ ++GDSAFGFSGMEIET R KL + Sbjct: 418 HRLDCGNLATMGVGLGYAISAKL----SRPDKTVVLIQGDSAFGFSGMEIETAVRNKLGL 473 Query: 723 I 725 I Sbjct: 474 I 474 Score = 33.5 bits (73), Expect = 5.4 Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = +1 Query: 364 EQKANTEFVEAQASSTAVPLNYYTVFKTVQQGI-PKDSIIVSEGANTMDMAEVYCST 531 E + N + E+ S++ LNY V+ ++++ + +++IIV EGANTMD+A + T Sbjct: 359 ENEINLKKKESNHSTSQ--LNYNEVYGSLRKILNDRETIIVMEGANTMDIARISFKT 413 >UniRef50_A6MJX0 Cluster: 2-hydroxyacyl-CoA lyase 1-like protein; n=2; Simiiformes|Rep: 2-hydroxyacyl-CoA lyase 1-like protein - Callithrix jacchus (Common marmoset) Length = 200 Score = 117 bits (281), Expect = 3e-25 Identities = 55/72 (76%), Positives = 61/72 (84%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGME 689 GR +L N PRHRLDAGTFGTMGVG GFAIAAAM +D PG+RVICVEGDSAFGFSGME Sbjct: 27 GRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAMVAKDRHPGQRVICVEGDSAFGFSGME 86 Query: 690 IETMFRYKLPVI 725 +ET+ RY LP+I Sbjct: 87 VETICRYNLPII 98 Score = 38.3 bits (85), Expect = 0.19 Identities = 16/26 (61%), Positives = 21/26 (80%) Frame = +1 Query: 433 TVFKTVQQGIPKDSIIVSEGANTMDM 510 TVF VQ+ +P+D +VSEGANTMD+ Sbjct: 1 TVFYHVQEQLPRDCFVVSEGANTMDI 26 >UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 478 Score = 116 bits (278), Expect = 8e-25 Identities = 86/253 (33%), Positives = 126/253 (49%), Gaps = 17/253 (6%) Frame = +3 Query: 15 TKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAPDV 194 T+L F+P+PMGKGVV D S+AR+ AL ADV+L+LGAR+NW+ H G+ P++ P+ Sbjct: 117 TQLTFIPSPMGKGVVPDSHPTNASSARSAALKMADVVLILGARLNWIFHHGEAPKWNPEA 176 Query: 195 KIIQVEISPEEF-HNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVGGRD*NRTK 371 K IQV+IS EE NS+ +E G +L ++ + K Sbjct: 177 KFIQVDISAEETGRNSESAEHSLLGDVGVVATQLLTWL--GDWTFDLNSSEYMAKIRQAK 234 Query: 372 SKHR-----ICRGSSK--QHCSTTELLH-CFQNSSTRHSKRFNHCQRRSEYHGYGRGLLL 527 K+ +G S ++ +++ N S R + + R + Sbjct: 235 EKNEKIASLTAQGPSMPLKYARAFDVMKTTLHNLSQPSEGRICYMAESTNTMDISRSIFP 294 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAA-----AMWCRDYA-PGKR--VICVEGDSAFGFSG 683 HPR RLDAGT+ TMG G +AIAA A+ + ++ P KR + +E DSAF S Sbjct: 295 LEHPRLRLDAGTYATMGFGLPYAIAASEAYNALTSQVFSGPTKRKKTVAIEDDSAFDLSV 354 Query: 684 MEIETMFRYKLPV 722 MEIETM R + + Sbjct: 355 MEIETMARMGMDI 367 >UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40; Eukaryota|Rep: 2-hydroxyacyl-CoA lyase 1 - Homo sapiens (Human) Length = 578 Score = 115 bits (277), Expect = 1e-24 Identities = 53/79 (67%), Positives = 60/79 (75%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E KLPFLPTPMGKGVV D YCV AR++AL ADVI+L GAR+NW+LHFG PPRY P Sbjct: 238 EQYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQP 297 Query: 189 DVKIIQVEISPEEFHNSKK 245 DVK IQV+I EE N+ K Sbjct: 298 DVKFIQVDICAEELGNNVK 316 Score = 113 bits (271), Expect = 6e-24 Identities = 52/72 (72%), Positives = 61/72 (84%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGME 689 GR +L N PRHRLDAGTFGTMGVG GFAIAAA+ +D +PG+ +ICVEGDSAFGFSGME Sbjct: 405 GRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGME 464 Query: 690 IETMFRYKLPVI 725 +ET+ RY LP+I Sbjct: 465 VETICRYNLPII 476 Score = 55.6 bits (128), Expect = 1e-06 Identities = 24/49 (48%), Positives = 35/49 (71%) Frame = +1 Query: 364 EQKANTEFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDM 510 + K+N + AS ++P+NYYTVF VQ+ +P+D +VSEGANTMD+ Sbjct: 356 KMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDI 404 >UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative; n=1; Tetrahymena thermophila SB210|Rep: 2-hydroxyphytanoyl-CoA lyase, putative - Tetrahymena thermophila SB210 Length = 405 Score = 107 bits (256), Expect = 4e-22 Identities = 47/79 (59%), Positives = 62/79 (78%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 ++T+LPFLPTPMGKGVV+D C + AR+ L AD+ILL+GAR+NW+LHFG+PPR+ Sbjct: 225 QSTQLPFLPTPMGKGVVSDLHPCCAAPARSFILQNADLILLIGARLNWILHFGEPPRFNK 284 Query: 189 DVKIIQVEISPEEFHNSKK 245 +VKII +EI PEEF + K Sbjct: 285 NVKIIHIEICPEEFDTNVK 303 >UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_27, whole genome shotgun sequence - Paramecium tetraurelia Length = 552 Score = 105 bits (253), Expect = 8e-22 Identities = 47/80 (58%), Positives = 64/80 (80%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E+TKLPFLP+PMGKGVV D + VS AR+ AL ADVILL+GAR+NW+LHFG PPR+ Sbjct: 228 ESTKLPFLPSPMGKGVVPDSNHLNVSAARSTALGDADVILLVGARLNWILHFGLPPRFDD 287 Query: 189 DVKIIQVEISPEEFHNSKKS 248 + + IQ++ PEEF+N++++ Sbjct: 288 NCQFIQIDNFPEEFNNNRRT 307 Score = 77.8 bits (183), Expect = 3e-13 Identities = 38/72 (52%), Positives = 51/72 (70%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGME 689 GR ++ ++ PR +LD+GTFGTMG+G FAIA+ + RD K+V + GDSAFGFSG E Sbjct: 391 GRTIIEHDLPRRKLDSGTFGTMGIGLPFAIASKLVFRD----KQVFAILGDSAFGFSGFE 446 Query: 690 IETMFRYKLPVI 725 ET RY LP++ Sbjct: 447 FETSTRYNLPLV 458 Score = 44.0 bits (99), Expect = 0.004 Identities = 20/60 (33%), Positives = 34/60 (56%) Frame = +1 Query: 331 SKQQLVAGTETEQKANTEFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDM 510 S +Q + ++ NT + + +PL YY+ F ++Q +P+D + V EGANTMD+ Sbjct: 331 SNKQWIDKLFDKRNKNTLTNQQLMNDKELPLEYYSAFGIIKQYLPRDCVYVGEGANTMDV 390 >UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 634 Score = 103 bits (247), Expect = 4e-21 Identities = 44/72 (61%), Positives = 59/72 (81%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGME 689 GR ++ + P+ RLDAGTFGTMGVG GF++AAA+W RD++P +V+ V+GDSAFGFS ME Sbjct: 463 GRTMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAME 522 Query: 690 IETMFRYKLPVI 725 +ET+ RY LPV+ Sbjct: 523 LETIARYNLPVV 534 Score = 98.7 bits (235), Expect = 1e-19 Identities = 42/79 (53%), Positives = 58/79 (73%) Frame = +3 Query: 15 TKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAPDV 194 +KLP+L TP GKGV +D + AR+ AL +AD + L+GAR NW+LHFG PPR+ DV Sbjct: 299 SKLPWLATPGGKGVASDLHPRFIGQARSLALREADTVFLIGARFNWILHFGLPPRFQKDV 358 Query: 195 KIIQVEISPEEFHNSKKSE 251 K++Q++I PEEFH + K+E Sbjct: 359 KVVQIDICPEEFHQNVKTE 377 Score = 38.7 bits (86), Expect = 0.14 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Frame = +1 Query: 376 NTEFVEAQASSTAVPLNYYTVFKTVQQGIP-KDSIIVSEGANTMDM 510 N VE + PLNYY ++ +++ + D I+++EGANTMD+ Sbjct: 417 NRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDVIVINEGANTMDI 462 >UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13; Magnoliophyta|Rep: Oxalyl-CoA decarboxylase - Arabidopsis thaliana (Mouse-ear cress) Length = 572 Score = 91.5 bits (217), Expect = 2e-17 Identities = 40/78 (51%), Positives = 56/78 (71%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E T +PFLPTPMGKG++ D E+ + AR+ A+ K DV L++GAR+NW+LHFG+ P++ Sbjct: 241 EITGIPFLPTPMGKGLLPDTHEFSATAARSLAIGKCDVALVVGARLNWLLHFGESPKWDK 300 Query: 189 DVKIIQVEISPEEFHNSK 242 DVK I V++S EE K Sbjct: 301 DVKFILVDVSEEEIELRK 318 Score = 85.0 bits (201), Expect = 2e-15 Identities = 41/72 (56%), Positives = 52/72 (72%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGME 689 GR +L+ PR RLDAGT+GTMGVG G+ IAAA+ +P + V+ VEGDS FGFS ME Sbjct: 411 GRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAV----ASPDRLVVAVEGDSGFGFSAME 466 Query: 690 IETMFRYKLPVI 725 +ET+ RY L V+ Sbjct: 467 VETLVRYNLAVV 478 Score = 37.1 bits (82), Expect = 0.44 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 4/59 (6%) Frame = +1 Query: 346 VAGTETEQKANTEFVEAQASSTAVPLNYYTVFKTVQQGI----PKDSIIVSEGANTMDM 510 V + K N E +E Q + VP N+ T + ++ I ++VSEGANTMD+ Sbjct: 352 VESISKKAKENGEKMEIQLAKDVVPFNFLTPMRIIRDAILAVEGPSPVVVSEGANTMDV 410 >UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 580 Score = 88.2 bits (209), Expect = 2e-16 Identities = 38/78 (48%), Positives = 55/78 (70%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E TK+PFLP+PMGKG++ D+ V AR+ AL ADV+L+LGAR+NWM +FG+ P ++ Sbjct: 228 EATKIPFLPSPMGKGLLRDDHPLVVGAARSYALKNADVVLVLGARLNWMFNFGKAPTFST 287 Query: 189 DVKIIQVEISPEEFHNSK 242 DVK I V++ + +K Sbjct: 288 DVKFIIVDVDENQASKTK 305 Score = 79.4 bits (187), Expect = 8e-14 Identities = 38/72 (52%), Positives = 50/72 (69%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGME 689 GR + PR RLDAGT TMGVG G+++AA + C P + V+C++GDSAFGFS ME Sbjct: 417 GRLCIPQTLPRSRLDAGTLATMGVGVGYSVAAQI-C---FPDRSVVCIQGDSAFGFSAME 472 Query: 690 IETMFRYKLPVI 725 +E RYKLP++ Sbjct: 473 MEVAVRYKLPIV 484 >UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3; Saccharomycetales|Rep: Uncharacterized protein YEL020C - Saccharomyces cerevisiae (Baker's yeast) Length = 560 Score = 85.8 bits (203), Expect = 1e-15 Identities = 39/76 (51%), Positives = 54/76 (71%) Frame = +3 Query: 21 LPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKI 200 LPFLPTPM KG+V D S VS+AR+QAL AD++L+LGAR+NW+LHFG P++ + Sbjct: 234 LPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293 Query: 201 IQVEISPEEFHNSKKS 248 IQ + +PE ++ S Sbjct: 294 IQFDSNPETLGDNNVS 309 Score = 66.5 bits (155), Expect = 6e-10 Identities = 33/63 (52%), Positives = 43/63 (68%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR RLDAGT TMG+G G+A+A C+ P V+ ++GDSAFGFS MEIET R +L Sbjct: 409 PRRRLDAGTNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQL 464 Query: 717 PVI 725 ++ Sbjct: 465 ALV 467 >UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Rep: AEL055Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 545 Score = 81.8 bits (193), Expect = 2e-14 Identities = 36/78 (46%), Positives = 52/78 (66%), Gaps = 1/78 (1%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E +LPFLP PM KG+V D E V+ R+ AL +A+++L+LGAR+NW+LH+G P++ Sbjct: 220 ERYRLPFLPVPMAKGIVPDSHELNVNGCRSLALKRAEIVLVLGARLNWILHYGSAPKWNA 279 Query: 189 DVKIIQVEISPEEF-HNS 239 D IQV+ P HN+ Sbjct: 280 DATFIQVDRDPATLGHNN 297 Score = 64.9 bits (151), Expect = 2e-09 Identities = 32/65 (49%), Positives = 46/65 (70%) Frame = +3 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 ++P+ RLDAGT TMG+G G+A++A + P K V+ +EGDSAFGFS ME+ET R Sbjct: 394 DYPKRRLDAGTGATMGLGVGYALSAKL----ANPDKFVVALEGDSAFGFSCMELETAVRN 449 Query: 711 KLPVI 725 K+ ++ Sbjct: 450 KVGLV 454 Score = 35.1 bits (77), Expect = 1.8 Identities = 16/39 (41%), Positives = 28/39 (71%), Gaps = 1/39 (2%) Frame = +1 Query: 418 PLNYYTVFKTVQQGIP-KDSIIVSEGANTMDMAEVYCST 531 PLNY+ V+ +++ I K++I+ +EGANTMD + ++ T Sbjct: 355 PLNYHAVYSLLRKLIDDKNTILSAEGANTMDNSRLWFGT 393 >UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60; Bacteria|Rep: Oxalyl-CoA decarboxylase - Oxalobacter formigenes Length = 568 Score = 79.8 bits (188), Expect = 6e-14 Identities = 39/62 (62%), Positives = 46/62 (74%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR RLD+GT+G MG+G G+ +AAA GK VI VEGDSAFGFSGME+ET+ RY L Sbjct: 416 PRKRLDSGTWGVMGIGMGYCVAAAA-----VTGKPVIAVEGDSAFGFSGMELETICRYNL 470 Query: 717 PV 722 PV Sbjct: 471 PV 472 Score = 59.3 bits (137), Expect = 1e-07 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E T +PFLP M KG++ D + R AL + DV +L+GAR+NW++ G+ + Sbjct: 238 EETGIPFLPMGMAKGLLPDNHPQSAAATRAFALAQCDVCVLIGARLNWLMQHGKGKTWGD 297 Query: 189 DV-KIIQVEISPEEFHNSK 242 ++ K +Q++I E +++ Sbjct: 298 ELKKYVQIDIQANEMDSNQ 316 >UniRef50_UPI000150A350 Cluster: Thiamine pyrophosphate enzyme, central domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Thiamine pyrophosphate enzyme, central domain containing protein - Tetrahymena thermophila SB210 Length = 561 Score = 77.0 bits (181), Expect = 4e-13 Identities = 35/71 (49%), Positives = 47/71 (66%) Frame = +3 Query: 21 LPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKI 200 LPFLPT GKGV++D+ CV A+ L DVILL+G +NW+L FGQ P++ D +I Sbjct: 244 LPFLPTLFGKGVISDKHNCCVIQAQNYVLQNTDVILLIGTGLNWILDFGQYPQFNRDAQI 303 Query: 201 IQVEISPEEFH 233 IQ+ PE F+ Sbjct: 304 IQIFNDPEYFN 314 Score = 34.7 bits (76), Expect = 2.4 Identities = 21/63 (33%), Positives = 31/63 (49%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P+ L +G GV F IA+ ++ K V+C+ D +F S +IE +YKL Sbjct: 433 PKQYLSSGNSIIKGVSIPFCIASKCVYKN----KPVVCIFDDESFNLSQADIEASSQYKL 488 Query: 717 PVI 725 P I Sbjct: 489 PFI 491 >UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central region; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Thiamine pyrophosphate protein central region - Anaeromyxobacter sp. Fw109-5 Length = 550 Score = 76.2 bits (179), Expect = 8e-13 Identities = 54/239 (22%), Positives = 103/239 (43%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 + T +P MG+G + + + +R +AL +ADV++++G +++ + +G P +AP Sbjct: 228 DRTGIPVYLNGMGRGCLPPDHPSALQLSRKEALAQADVVVVVGTPLDFRVGYGTEPTFAP 287 Query: 189 DVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVGGRD*NRT 368 +++QV++ E ++ + G + + + ++ +R Sbjct: 288 GARVVQVDVDGAEIGRNRPIDVGIVGDARSVLEQLEAGARLAPAAEAWRAFLRQQETSRA 347 Query: 369 KSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLLNNHPRHR 548 + K R S ++ L ++R +L P Sbjct: 348 E-KQRGYEESDQRPIHHFRLAKALDTVASRAGD-VTFVGDGGNVVAVAAKVLKVKKPGRW 405 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 LD G G +GVG FAIAA + AP + V ++GD AFG +G + ET R+ LP++ Sbjct: 406 LDPGPLGCLGVGAPFAIAAKL----LAPERPVCVIQGDGAFGLNGFDFETAVRFGLPMV 460 >UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate synthase)-like; n=36; cellular organisms|Rep: IlvB (Bacterial acetolactate synthase)-like - Homo sapiens (Human) Length = 632 Score = 64.9 bits (151), Expect = 2e-09 Identities = 65/245 (26%), Positives = 106/245 (43%), Gaps = 4/245 (1%) Frame = +3 Query: 3 ARENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRY 182 A E +P M +G++ + R+ AL KADVI+L G ++ L +G+ + Sbjct: 307 AVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSH 366 Query: 183 APDVKIIQVEISPEEFH-NSK---KSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVGG 350 + KII V+ + EE NS K + G + + + Sbjct: 367 SS--KIIIVDRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELRE 424 Query: 351 RD*NRTKSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLLN 530 D + ++ QH + ++L + + +S ++ G L+ Sbjct: 425 ADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVD---GGDFVGTAAHLVQP 481 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 P LD G FGT+GVG GFA+ A + CR P V C+ GD AFG+S +E +T R+ Sbjct: 482 RGPLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRH 537 Query: 711 KLPVI 725 K+PV+ Sbjct: 538 KIPVM 542 >UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12; Mycobacterium|Rep: Probable acetolactate synthase - Mycobacterium bovis Length = 547 Score = 60.9 bits (141), Expect = 3e-08 Identities = 29/77 (37%), Positives = 49/77 (63%) Frame = +3 Query: 495 EYHGYGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFG 674 ++ Y ++ + P LD+G FG +G GPG+A+AA + P ++V+ ++GD AFG Sbjct: 388 DFGSYAGRMIDSYLPGCWLDSGPFGCLGSGPGYALAAKL----ARPQRQVVLLQGDGAFG 443 Query: 675 FSGMEIETMFRYKLPVI 725 FSGME +T+ R+ + V+ Sbjct: 444 FSGMEWDTLVRHNVAVV 460 Score = 40.7 bits (91), Expect = 0.036 Identities = 21/53 (39%), Positives = 31/53 (58%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFG 167 E +P L M +GVV + S AR++AL +ADV L++G M++ L FG Sbjct: 234 EERHIPVLMNGMARGVVPADHRLAFSRARSKALGEADVALIVGVPMDFRLGFG 286 >UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3; Eukaryota|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 904 Score = 58.4 bits (135), Expect = 2e-07 Identities = 31/62 (50%), Positives = 41/62 (66%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P LD G FGT+GVG GF+IAA + CR P +V + GD AFG+S E++TM R+K+ Sbjct: 757 PLSWLDPGVFGTLGVGAGFSIAAKL-CR---PDHQVWTIYGDGAFGYSIPELDTMVRHKI 812 Query: 717 PV 722 V Sbjct: 813 SV 814 >UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2; Rhodopseudomonas palustris|Rep: Possible benzaldehyde lyase - Rhodopseudomonas palustris Length = 600 Score = 58.0 bits (134), Expect = 2e-07 Identities = 30/77 (38%), Positives = 44/77 (57%) Frame = +3 Query: 495 EYHGYGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFG 674 E +G + + P L G G +G+GPGFAI A + AP +RVI + GD A G Sbjct: 417 EAASWGAAAAVVDRPGALLGHGYLGCLGIGPGFAIGAQL----AAPERRVIHLTGDGALG 472 Query: 675 FSGMEIETMFRYKLPVI 725 F E++TM R++LP++ Sbjct: 473 FHLQELDTMVRHRLPIV 489 >UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n=1; Bos taurus|Rep: UPI0000F347A9 UniRef100 entry - Bos Taurus Length = 442 Score = 57.6 bits (133), Expect = 3e-07 Identities = 30/59 (50%), Positives = 39/59 (66%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 LD G FGT+GVG GFA+ A + CR A V C+ GD AFG+S E +T R+K+PV+ Sbjct: 382 LDPGAFGTLGVGAGFALGAKL-CRLDA---EVWCLFGDGAFGYSLFEFDTFVRHKIPVM 436 >UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP binding region; n=3; Bacteria|Rep: Thiamine pyrophosphate enzyme-like TPP binding region - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 640 Score = 55.2 bits (127), Expect = 2e-06 Identities = 26/63 (41%), Positives = 38/63 (60%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P +D G G++GVG GFAIAA + PGK V+C GD +FG + ++ET R+ + Sbjct: 486 PGQWMDPGALGSLGVGTGFAIAAGV----ANPGKEVLCYYGDGSFGMTAFDMETANRFGV 541 Query: 717 PVI 725 P + Sbjct: 542 PYL 544 >UniRef50_A2SP25 Cluster: Acetolactate synthase-like TPP-requiring enzyme; n=3; Proteobacteria|Rep: Acetolactate synthase-like TPP-requiring enzyme - Methylibium petroleiphilum (strain PM1) Length = 586 Score = 54.4 bits (125), Expect = 3e-06 Identities = 27/59 (45%), Positives = 36/59 (61%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 LD G G +GVG F I AA+ C P + V + GD AFGF+ MEI+T R+ +PV+ Sbjct: 413 LDPGPLGCIGVGTSFGIGAALAC----PQRTVAVLTGDGAFGFNAMEIDTAVRHGVPVL 467 Score = 39.5 bits (88), Expect = 0.083 Identities = 18/49 (36%), Positives = 31/49 (63%) Frame = +3 Query: 27 FLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQP 173 FL T KGV+AD+ V+ R A+ +AD+++ LG ++++ L +G P Sbjct: 241 FLDTGECKGVLADDHPGLVNAMRATAMGEADLVITLGRKLDFQLAYGSP 289 >UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP binding domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Thiamine pyrophosphate enzyme TPP binding domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 568 Score = 53.6 bits (123), Expect = 5e-06 Identities = 26/63 (41%), Positives = 38/63 (60%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P LD G GT+GVG FAIAA + P + V+ + GD AFG +G + +T+ R+ L Sbjct: 418 PGQWLDPGPLGTLGVGTPFAIAA----KAAMPARDVVVLFGDGAFGLTGFDYDTLIRFNL 473 Query: 717 PVI 725 P++ Sbjct: 474 PMV 476 >UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep: Ilvbl-prov protein - Xenopus laevis (African clawed frog) Length = 649 Score = 52.4 bits (120), Expect = 1e-05 Identities = 32/77 (41%), Positives = 42/77 (54%) Frame = +3 Query: 495 EYHGYGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFG 674 ++ G +L P LD G FGT+GVG GFA+ A + CR P V V GD + G Sbjct: 474 DFVGSAAYILRPRGPLSWLDPGPFGTLGVGGGFALGAKL-CR---PQAHVWVVYGDGSAG 529 Query: 675 FSGMEIETMFRYKLPVI 725 +S E +TM R+K P I Sbjct: 530 YSLAEWDTMARHKAPAI 546 >UniRef50_A4IL27 Cluster: Acetolactate synthase; n=1; Geobacillus thermodenitrificans NG80-2|Rep: Acetolactate synthase - Geobacillus thermodenitrificans (strain NG80-2) Length = 557 Score = 52.4 bits (120), Expect = 1e-05 Identities = 28/62 (45%), Positives = 36/62 (58%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L +G GTMG G AI AA+ +PGK+VIC+ GD F + E+ T YKL Sbjct: 402 PRTFLTSGGLGTMGYGLPAAIGAAV----ASPGKKVICISGDGCFQMNVQEMMTAVAYKL 457 Query: 717 PV 722 P+ Sbjct: 458 PI 459 >UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2; Proteobacteria|Rep: Pyruvate decarboxylase - Congregibacter litoralis KT71 Length = 565 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/59 (47%), Positives = 36/59 (61%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 LD G G +GVG FA AAA+ C+ P K+V+ V GD +FGF+ MEI T R V+ Sbjct: 403 LDPGALGCIGVGGAFANAAAL-CQ---PDKKVVAVIGDGSFGFNAMEIHTSSRKDAKVV 457 Score = 41.1 bits (92), Expect = 0.027 Identities = 20/81 (24%), Positives = 42/81 (51%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E T +L T +G + V R A+ ++DVI+ LG ++++ + FG P + Sbjct: 226 EKTGAIYLDTTESRGALPGGHPANVPAMRGNAMKESDVIITLGRKLDFQVAFGSPAIFGA 285 Query: 189 DVKIIQVEISPEEFHNSKKSE 251 D K I+V + ++ +++++ Sbjct: 286 DTKFIRVGRNDDDVSGNRRAD 306 >UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP binding domain protein; n=3; Mycobacterium|Rep: Thiamine pyrophosphate enzyme TPP binding domain protein - Mycobacterium sp. (strain JLS) Length = 588 Score = 50.8 bits (116), Expect = 3e-05 Identities = 29/59 (49%), Positives = 36/59 (61%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 L G GT+GVGPGFAI AA R AP V+ + GD A GF E +TM R+ +PV+ Sbjct: 427 LRLGYLGTLGVGPGFAIGAAR-ARPAAP---VVLITGDGAAGFHLGEFDTMARHGMPVL 481 >UniRef50_Q607C4 Cluster: Acetolactate synthase; n=1; Methylococcus capsulatus|Rep: Acetolactate synthase - Methylococcus capsulatus Length = 553 Score = 50.4 bits (115), Expect = 4e-05 Identities = 28/63 (44%), Positives = 38/63 (60%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PRH L + TMGV +AI AA+ PGK+V+ V GD +F + ME+ET R KL Sbjct: 404 PRHLLFSMGHQTMGVALPWAIGAAL----ARPGKKVVSVSGDGSFLMTCMELETAVRLKL 459 Query: 717 PVI 725 P++ Sbjct: 460 PIV 462 >UniRef50_A1ICC6 Cluster: Putative TPP-requiring enzyme; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative TPP-requiring enzyme - Candidatus Desulfococcus oleovorans Hxd3 Length = 557 Score = 50.0 bits (114), Expect = 6e-05 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 4/85 (4%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVS----TARTQALLKADVILLLGARMNWMLHFGQPP 176 E T LPF G+GV+ D V+ T T L DVI+ G R NW+L G Sbjct: 230 EKTGLPFALVNYGRGVLPDTHSQSVNPGGFTGLTAGLPMCDVIVAAGIRFNWVLQSGS-- 287 Query: 177 RYAPDVKIIQVEISPEEFHNSKKSE 251 PD K+I+++I P E ++ ++ Sbjct: 288 -LFPDAKVIRIDIDPAELDRNRAAD 311 Score = 46.8 bits (106), Expect = 5e-04 Identities = 23/56 (41%), Positives = 33/56 (58%) Frame = +3 Query: 558 GTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G G +G G FA+AA + P K VI + GD +FGF+ ME +T R+ +P+I Sbjct: 411 GLLGCLGTGIPFALAAKL----AHPDKPVIVLNGDGSFGFNSMEFDTAVRHNIPII 462 >UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain protein TPP-binding; n=4; Actinomycetales|Rep: Thiamine pyrophosphate enzyme domain protein TPP-binding - Nocardioides sp. (strain BAA-499 / JS614) Length = 551 Score = 49.6 bits (113), Expect = 8e-05 Identities = 25/59 (42%), Positives = 37/59 (62%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 LD G +G +G G G AIAA + P +V+ + GD A GFS M+++T+ R+ LPV+ Sbjct: 410 LDPGPYGCLGAGLGAAIAARL----ARPSAQVVLLLGDGAAGFSLMDVDTLVRHHLPVV 464 Score = 34.7 bits (76), Expect = 2.4 Identities = 17/53 (32%), Positives = 31/53 (58%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFG 167 E +P + MG+GVV V+ AR QAL +D+++++G +++ L +G Sbjct: 229 EAVGIPTITNGMGRGVVPGGHPLLVTKARGQALGGSDLVVVVGTPLDFRLGYG 281 >UniRef50_Q01Q83 Cluster: Thiamine pyrophosphate enzyme domain protein TPP-binding; n=1; Solibacter usitatus Ellin6076|Rep: Thiamine pyrophosphate enzyme domain protein TPP-binding - Solibacter usitatus (strain Ellin6076) Length = 548 Score = 48.4 bits (110), Expect = 2e-04 Identities = 27/77 (35%), Positives = 41/77 (53%) Frame = +3 Query: 495 EYHGYGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFG 674 ++ +GR +L H L G GT+G AIA + PG+RV+ + GD A G Sbjct: 376 DFAHWGRAILPARHAGGWLRLGPLGTIGSSLPNAIALQL----AHPGRRVVAITGDGALG 431 Query: 675 FSGMEIETMFRYKLPVI 725 F E++T R+KLP++ Sbjct: 432 FYLAEMDTAARFKLPIV 448 Score = 43.2 bits (97), Expect = 0.007 Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 7/80 (8%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADE-------SEYCVSTARTQALLKADVILLLGARMNWMLHFG 167 E T++P M +G V DE ++ ++ A +AD+ +++G R+++ L G Sbjct: 219 ERTQIPLYTITMARGAVPDEHPLSMGYADPALNHAVHTVFREADLFIVIGKRIDYRLALG 278 Query: 168 QPPRYAPDVKIIQVEISPEE 227 P + D K IQV++ P+E Sbjct: 279 GPRLFPADAKFIQVDLHPQE 298 >UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central region precursor; n=3; Chloroflexaceae|Rep: Thiamine pyrophosphate enzyme, central region precursor - Roseiflexus sp. RS-1 Length = 847 Score = 48.4 bits (110), Expect = 2e-04 Identities = 24/56 (42%), Positives = 34/56 (60%) Frame = +3 Query: 558 GTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G+ G +GVG GFAI A + P V+ + GD AFG G+E +T R++LP+I Sbjct: 704 GSTGHIGVGLGFAIGARL----AHPDSPVVAIMGDGAFGLCGLEFDTAVRHQLPII 755 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/78 (26%), Positives = 41/78 (52%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E T +P L + +G++ D+ T A + AD L++G R++W + +G+ P + Sbjct: 519 ETTGIPVLSRNLARGIIPDDHPLSAGFYPTPAAM-ADAFLVIGTRLDWTIGYGRFPLFNL 577 Query: 189 DVKIIQVEISPEEFHNSK 242 D ++QV+I E ++ Sbjct: 578 DAPVVQVDIHAESIGKTR 595 >UniRef50_A6PTN2 Cluster: Thiamine pyrophosphate enzyme TPP binding domain protein; n=1; Victivallis vadensis ATCC BAA-548|Rep: Thiamine pyrophosphate enzyme TPP binding domain protein - Victivallis vadensis ATCC BAA-548 Length = 610 Score = 47.6 bits (108), Expect = 3e-04 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 4/85 (4%) Frame = +3 Query: 480 CQRRSEYHGYGRGLLLNN-HPRHRLDAGT--FGTMGVGP-GFAIAAAMWCRDYAPGKRVI 647 C R E G G+ + L AG FG +G G+ + AA+ APG+RVI Sbjct: 385 CLRGEEIIVTGNGIAYTSLFQAISLKAGNRMFGNVGCASMGYGLPAAIGAACAAPGRRVI 444 Query: 648 CVEGDSAFGFSGMEIETMFRYKLPV 722 CV GD + + E++T+ Y+LPV Sbjct: 445 CVTGDGSLQMNLQELQTLVTYRLPV 469 >UniRef50_A1HPN8 Cluster: Acetolactate synthase, large subunit, biosynthetic type; n=2; Acidaminococcaceae|Rep: Acetolactate synthase, large subunit, biosynthetic type - Thermosinus carboxydivorans Nor1 Length = 556 Score = 47.2 bits (107), Expect = 4e-04 Identities = 26/65 (40%), Positives = 35/65 (53%) Frame = +3 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 N R+ + +G GTMG G A+ A + C P RVI + GD F +GME+ T Sbjct: 401 NGSRNWITSGGLGTMGFGLPAALGAQLAC----PDSRVILIAGDGGFKMTGMELYTAVNE 456 Query: 711 KLPVI 725 KLP+I Sbjct: 457 KLPLI 461 >UniRef50_Q41EN3 Cluster: Pyruvate decarboxylase; n=1; Exiguobacterium sibiricum 255-15|Rep: Pyruvate decarboxylase - Exiguobacterium sibiricum 255-15 Length = 541 Score = 46.4 bits (105), Expect = 7e-04 Identities = 24/63 (38%), Positives = 34/63 (53%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P + F +MG G AIAA + P +RV+C GD AF +G ++ET R KL Sbjct: 393 PNQLFISNGFSSMGYGLSSAIAAKL----LHPEQRVLCASGDGAFLMNGQDLETAVRLKL 448 Query: 717 PVI 725 P++ Sbjct: 449 PIV 451 >UniRef50_A5TSK5 Cluster: Acetolactate synthase; n=1; Fusobacterium nucleatum subsp. polymorphum ATCC 10953|Rep: Acetolactate synthase - Fusobacterium nucleatum subsp. polymorphum ATCC 10953 Length = 573 Score = 46.0 bits (104), Expect = 0.001 Identities = 55/245 (22%), Positives = 95/245 (38%), Gaps = 7/245 (2%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCV-------STARTQALLKADVILLLGARMNWMLHFG 167 E T +P T +G G E + +T A +AD+I+ G R + + G Sbjct: 237 EKTNIPVAMTLLGLGSFPGNHELALGMIGMHGTTYANYAANEADLIIAAGMRFDDRVT-G 295 Query: 168 QPPRYAPDVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVG 347 P ++ P+ KII ++I P E +K + PK S LK Sbjct: 296 NPQKFVPNAKIIHIDIDPAEIGKNKLIDVPIVGDLKNVLTDLNEKAPKVSYDEWLKQI-- 353 Query: 348 GRD*NRTKSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLL 527 + K ++ + ++ + + + T+ + ++ + L Sbjct: 354 ----KKWKKEYSLTYRKTEDDILIPQEILSEIDKITKGNVIV--ATDVGQHQMWAAQYLT 407 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFR 707 N+P L +G GTMG F + AA+ + P K+V+ V GD F + E+ + Sbjct: 408 FNNPYSILTSGGAGTMG----FGLPAAIGAQVANPNKKVLAVVGDGGFQMTFQELMLIKE 463 Query: 708 YKLPV 722 Y LPV Sbjct: 464 YNLPV 468 >UniRef50_P42463 Cluster: Acetolactate synthase large subunit; n=69; cellular organisms|Rep: Acetolactate synthase large subunit - Corynebacterium glutamicum (Brevibacterium flavum) Length = 626 Score = 45.2 bits (102), Expect = 0.002 Identities = 53/237 (22%), Positives = 91/237 (38%), Gaps = 7/237 (2%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCV-------STARTQALLKADVILLLGARMNWMLHFG 167 E T +P + T M G + E + + + AL ++D+++ +G+R + + G Sbjct: 251 EYTGIPVVTTLMALGTFPESHELHMGMPGMHGTVSAVGALQRSDLLIAIGSRFDDRVT-G 309 Query: 168 QPPRYAPDVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVG 347 +APD KII +I P E K+ E +S + Sbjct: 310 DVDTFAPDAKIIHADIDPAEIGKIKQVEVPIVGDAREVLARLLETTK--ASKAETEDISE 367 Query: 348 GRD*NRTKSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLL 527 D + K R RG +Q + S +C ++ + + Sbjct: 368 WVDYLKGL-KARFPRGYDEQPGDLLAPQFVIETLSKEVGPDAIYCAGVGQHQMWAAQFVD 426 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 PR L++G GTMG +A+ AA+ + AP K V ++GD F + E+ T Sbjct: 427 FEKPRTWLNSGGLGTMG----YAVPAALGAKAGAPDKEVWAIDGDGCFQMTNQELTT 479 >UniRef50_P40811 Cluster: Acetolactate synthase isozyme 3 large subunit; n=249; Bacteria|Rep: Acetolactate synthase isozyme 3 large subunit - Salmonella typhimurium Length = 574 Score = 44.8 bits (101), Expect = 0.002 Identities = 22/63 (34%), Positives = 36/63 (57%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR +++G GTMG F + AA+ + P + V+CV GD + + E+ T +Y+L Sbjct: 411 PRRWINSGGLGTMG----FGLPAALGVKMALPKEMVVCVTGDGSIQMNIQELSTALQYEL 466 Query: 717 PVI 725 PV+ Sbjct: 467 PVL 469 >UniRef50_P51853 Cluster: Benzaldehyde lyase; n=3; Pseudomonas fluorescens|Rep: Benzaldehyde lyase - Pseudomonas fluorescens Length = 563 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/56 (42%), Positives = 34/56 (60%) Frame = +3 Query: 558 GTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G G+MGVG G A+ A + D G+R I V GD + G+S E +T+ R +LP+I Sbjct: 416 GYLGSMGVGFGTALGAQV--ADLEAGRRTILVTGDGSVGYSIGEFDTLVRKQLPLI 469 >UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain protein TPP-binding; n=2; Bacteria|Rep: Thiamine pyrophosphate enzyme domain protein TPP-binding - Nocardioides sp. (strain BAA-499 / JS614) Length = 588 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/63 (39%), Positives = 34/63 (53%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L FG +G G G A+ AA+ AP +RV + GD AFG E+E+ R L Sbjct: 416 PRTILSTYKFGMLGAGMGQALGAAV----AAPDQRVCVLIGDGAFGMHPTEVESAVRLGL 471 Query: 717 PVI 725 P++ Sbjct: 472 PIV 474 >UniRef50_Q04789 Cluster: Acetolactate synthase; n=69; Bacteria|Rep: Acetolactate synthase - Bacillus subtilis Length = 571 Score = 44.4 bits (100), Expect = 0.003 Identities = 22/52 (42%), Positives = 32/52 (61%) Frame = +3 Query: 570 TMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 T+GV +AI A++ PG++V+ V GD F FS ME+ET R K P++ Sbjct: 425 TLGVALPWAIGASL----VKPGEKVVSVSGDGGFLFSAMELETAVRLKAPIV 472 >UniRef50_O08353 Cluster: Probable acetolactate synthase large subunit; n=12; Archaea|Rep: Probable acetolactate synthase large subunit - Methanococcus aeolicus Length = 599 Score = 44.4 bits (100), Expect = 0.003 Identities = 24/63 (38%), Positives = 33/63 (52%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L +G GTMG G AI A + P +VIC+ GD F + E+ T+ Y + Sbjct: 418 PRSFLSSGGLGTMGFGFPSAIGAKV----AKPDSKVICITGDGGFMMNCQELGTIAEYNI 473 Query: 717 PVI 725 PV+ Sbjct: 474 PVV 476 >UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requiring enzyme; n=1; Symbiobacterium thermophilum|Rep: Acetolactate synthase-like TPP-requiring enzyme - Symbiobacterium thermophilum Length = 551 Score = 44.0 bits (99), Expect = 0.004 Identities = 24/67 (35%), Positives = 35/67 (52%) Frame = +3 Query: 525 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 + +P +D G GT+G+G GFA+AA R P V+ + GD G + ME+E Sbjct: 402 VRRYPAGWMDPGPLGTLGIGMGFAMAA----RLAHPDVPVVLLLGDGTAGLNLMEVEAAV 457 Query: 705 RYKLPVI 725 R LP + Sbjct: 458 RQNLPFV 464 Score = 35.9 bits (79), Expect = 1.0 Identities = 16/46 (34%), Positives = 28/46 (60%) Frame = +3 Query: 90 ARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKIIQVEISPEE 227 +R AL +ADV L+ G +++ L +G P + ++IQV++ P E Sbjct: 257 SRKAALAEADVALVFGTPLDFRLGYGGSPVWNEQCRLIQVDLDPAE 302 >UniRef50_Q5LQV0 Cluster: Benzaldehyde lyase, putative; n=1; Silicibacter pomeroyi|Rep: Benzaldehyde lyase, putative - Silicibacter pomeroyi Length = 576 Score = 43.6 bits (98), Expect = 0.005 Identities = 23/59 (38%), Positives = 32/59 (54%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 L G + +GVG FA+AA RD K + V GD AF G+ IET F+ +P++ Sbjct: 426 LHPGNYSLLGVGVSFALAAKNLNRD----KTTVLVTGDGAFLSGGLSIETCFQENIPIV 480 Score = 39.5 bits (88), Expect = 0.083 Identities = 17/42 (40%), Positives = 29/42 (69%) Frame = +3 Query: 102 ALLKADVILLLGARMNWMLHFGQPPRYAPDVKIIQVEISPEE 227 A+ +ADV++++G R++ ++FG PP P+ K+I V S EE Sbjct: 272 AIHEADVVVMVGCRLDNQMNFGNPPFIQPETKLICVNGSHEE 313 >UniRef50_Q5LKS2 Cluster: Sulphoacetaldehyde acetyltransferase, putative; n=1; Silicibacter pomeroyi|Rep: Sulphoacetaldehyde acetyltransferase, putative - Silicibacter pomeroyi Length = 559 Score = 43.6 bits (98), Expect = 0.005 Identities = 18/45 (40%), Positives = 30/45 (66%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 GF +AAA+ + AP + V+ + GD A G++ +EI+T +KLP+ Sbjct: 418 GFGLAAAIGAKAAAPERPVVAIMGDGAVGYTMIEIQTAISHKLPI 462 >UniRef50_Q88Y01 Cluster: Acetolactate synthase; n=25; Bacilli|Rep: Acetolactate synthase - Lactobacillus plantarum Length = 560 Score = 43.2 bits (97), Expect = 0.007 Identities = 24/63 (38%), Positives = 34/63 (53%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PRH L + T+GV +AIAAA+ P +++ V GD F FS E+ET R K Sbjct: 411 PRHLLFSNGMQTLGVALPWAIAAAL----VRPDTQIVSVSGDGGFLFSAQELETAVRLKQ 466 Query: 717 PVI 725 ++ Sbjct: 467 NIV 469 >UniRef50_Q7WPE1 Cluster: Thiamine pyrophosphate enzyme; n=2; Proteobacteria|Rep: Thiamine pyrophosphate enzyme - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 558 Score = 43.2 bits (97), Expect = 0.007 Identities = 24/62 (38%), Positives = 34/62 (54%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR + G GT+G G A+ AA+ G+RV+ + GD FG++ E+ T RY L Sbjct: 396 PRTYIGPGYQGTLGYGFPVALGAAVG----GAGRRVLSITGDGGFGWNLQELATARRYNL 451 Query: 717 PV 722 PV Sbjct: 452 PV 453 >UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1; uncultured delta proteobacterium DeepAnt-32C6|Rep: IlvB acetolactate synthase - uncultured delta proteobacterium DeepAnt-32C6 Length = 680 Score = 43.2 bits (97), Expect = 0.007 Identities = 25/69 (36%), Positives = 38/69 (55%) Frame = +3 Query: 519 LLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 L + R L+ G FG+MG G A+ AA+ AP + V+ + GD+ F +GME+ T Sbjct: 522 LCIGREQRFMLNLG-FGSMGHGTSAAVGAAL----AAPERPVVSIIGDACFTMNGMELLT 576 Query: 699 MFRYKLPVI 725 Y +PV+ Sbjct: 577 AREYGVPVV 585 >UniRef50_Q7U5G1 Cluster: Acetolactate synthase large subunit; n=60; cellular organisms|Rep: Acetolactate synthase large subunit - Synechococcus sp. (strain WH8102) Length = 617 Score = 42.7 bits (96), Expect = 0.009 Identities = 23/66 (34%), Positives = 36/66 (54%) Frame = +3 Query: 525 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 L N PR + + GTMG F + AAM + P ++V+C+ GD++ + E+ T+ Sbjct: 422 LRNGPRGWISSAGLGTMG----FGMPAAMGAQVAMPDRQVVCIAGDASILMNIQELGTLA 477 Query: 705 RYKLPV 722 Y LPV Sbjct: 478 AYGLPV 483 >UniRef50_A3X9K6 Cluster: Acetolactate synthase-like TPP-requiring enzyme; n=1; Roseobacter sp. MED193|Rep: Acetolactate synthase-like TPP-requiring enzyme - Roseobacter sp. MED193 Length = 573 Score = 42.3 bits (95), Expect = 0.012 Identities = 24/73 (32%), Positives = 36/73 (49%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQALLKADVILLLGARMNWMLHFGQPPRYAP 188 E LP L T MG+G++ D V A+ +AL D +LL GA ++W F P Sbjct: 264 EELDLPVLATDMGRGILPDGHRLSVFLAKEEALQNCDHVLLCGADLDW--RFSARSLLGP 321 Query: 189 DVKIIQVEISPEE 227 +V I + + E+ Sbjct: 322 EVPIDPLPLEFED 334 Score = 40.7 bits (91), Expect = 0.036 Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Frame = +3 Query: 510 GRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKR--VICVEGDSAFGFSG 683 G L + P R+ G GT+GVG FA+ AAM +R V+ + GD FG S Sbjct: 407 GHNLWAVHRPFSRVTPGQNGTIGVGIPFALGAAMQQLQLPVEQRQWVVALVGDVGFGLSA 466 Query: 684 MEIETMFR 707 E+ET R Sbjct: 467 SELETAQR 474 >UniRef50_A3DID9 Cluster: Acetolactate synthase; n=3; Clostridium|Rep: Acetolactate synthase - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 542 Score = 42.3 bits (95), Expect = 0.012 Identities = 54/241 (22%), Positives = 96/241 (39%), Gaps = 7/241 (2%) Frame = +3 Query: 21 LPFLPTPMGKGVVADESEYCVSTARTQ-------ALLKADVILLLGARMNWMLHFGQPPR 179 +P + T MG G V + E + T A+ AD+++++GAR+ P + Sbjct: 231 IPVVTTLMGIGSVPYDYELNLGMLGTHGVYIANYAVNNADLLIIIGARVADRA-ISNPQQ 289 Query: 180 YAPDVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXGCPKGSSHCNLKTTVGGRD* 359 A +I+ ++I P E + KG + +KTT R+ Sbjct: 290 VAKRKQIVHIDIDPAEIGKNIDVSIPVVGDVKQVLKELIDISQKGDTEEWIKTTQKEREK 349 Query: 360 NRTKSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLLNNHP 539 + K + R G + L + ++ + + Y G + P Sbjct: 350 HAEKPEPRPGIGFVNPKYLLSVLTGLLGDDDIITTEVGQNQIWAANYFGVKK-------P 402 Query: 540 RHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLP 719 R + +G GTMG G A+ A + C P ++V+CV GD +F + E+ T+ + +L Sbjct: 403 RTFITSGGLGTMGYGLPAAVGAKIGC----PDRKVVCVGGDGSFQMNMQELGTIKQNRLG 458 Query: 720 V 722 V Sbjct: 459 V 459 >UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=5; Peptococcaceae|Rep: Sulfoacetaldehyde acetyltransferase - Desulfonispora thiosulfatigenes Length = 584 Score = 41.9 bits (94), Expect = 0.016 Identities = 25/63 (39%), Positives = 33/63 (52%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P+ + A TFG G FA A + + P V+ + GD A+G S EI T +YKL Sbjct: 413 PKKHIAALTFGNTG----FAYQAGLGAQMAEPDSPVVAIVGDGAWGQSLHEISTAVQYKL 468 Query: 717 PVI 725 PVI Sbjct: 469 PVI 471 >UniRef50_Q9WZ18 Cluster: Acetolactate synthase; n=7; cellular organisms|Rep: Acetolactate synthase - Thermotoga maritima Length = 584 Score = 41.5 bits (93), Expect = 0.021 Identities = 24/63 (38%), Positives = 33/63 (52%) Frame = +3 Query: 534 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYK 713 H R L +G GTMG +A+ A + + AP K V+ GD F + E+ T+ RY Sbjct: 404 HQRSFLCSGGLGTMG----YALPAGIGAKIGAPDKEVVVFAGDGGFQMNIQELMTIKRYN 459 Query: 714 LPV 722 LPV Sbjct: 460 LPV 462 >UniRef50_Q2LXP1 Cluster: Acetolactate synthase large subunit; n=1; Syntrophus aciditrophicus SB|Rep: Acetolactate synthase large subunit - Syntrophus aciditrophicus (strain SB) Length = 557 Score = 41.5 bits (93), Expect = 0.021 Identities = 22/62 (35%), Positives = 34/62 (54%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR + +G GTMG F++ AAM + AP + V+ + GD F + E+ T+ Y + Sbjct: 399 PRSLITSGGMGTMG----FSVPAAMGAKIGAPDRSVVAICGDGGFYMNIQELATISYYNI 454 Query: 717 PV 722 PV Sbjct: 455 PV 456 >UniRef50_A5GC69 Cluster: Acetolactate synthase; n=3; cellular organisms|Rep: Acetolactate synthase - Geobacter uraniumreducens Rf4 Length = 560 Score = 41.5 bits (93), Expect = 0.021 Identities = 24/62 (38%), Positives = 33/62 (53%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR + +G GTMG +A+ AAM PG+ VI + GD AF + E+ T Y + Sbjct: 399 PRRFITSGGLGTMG----YALPAAMGAVLGNPGETVIAITGDGAFQMNIQELATCAYYNI 454 Query: 717 PV 722 PV Sbjct: 455 PV 456 >UniRef50_Q9K659 Cluster: Acetolactate synthase large subunit; n=2; Bacillus|Rep: Acetolactate synthase large subunit - Bacillus halodurans Length = 543 Score = 41.1 bits (92), Expect = 0.027 Identities = 22/54 (40%), Positives = 28/54 (51%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 FG MG G AI AAM R + +C+ GD F GME+ T Y LP++ Sbjct: 399 FGAMGTAIGSAIGAAMVDRK----RPTVCITGDGCFFMHGMEVLTAKEYGLPIL 448 >UniRef50_Q97EE4 Cluster: Acetolactate synthase; n=10; Clostridiales|Rep: Acetolactate synthase - Clostridium acetobutylicum Length = 554 Score = 41.1 bits (92), Expect = 0.027 Identities = 24/62 (38%), Positives = 33/62 (53%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR + +G GTMG G G AI A++ K + GD +F + E+ T+ RYKL Sbjct: 399 PRSFITSGGLGTMGYGFGAAIGASV-----GKDKMTFDIAGDGSFRMNINELATVVRYKL 453 Query: 717 PV 722 PV Sbjct: 454 PV 455 >UniRef50_Q7W2M5 Cluster: Acetolactate synthase large subunit; n=53; Proteobacteria|Rep: Acetolactate synthase large subunit - Bordetella parapertussis Length = 616 Score = 41.1 bits (92), Expect = 0.027 Identities = 22/64 (34%), Positives = 35/64 (54%) Frame = +3 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 + P L +G GTMG G + AA+ + PGK V+CV GD++ + E+ T ++ Sbjct: 441 DRPNRWLTSGGAGTMGYG----VPAAIGAQIAHPGKTVVCVSGDASVLMNIQELSTAMQH 496 Query: 711 KLPV 722 +PV Sbjct: 497 DVPV 500 >UniRef50_A6BEJ7 Cluster: Acetolactate synthase; n=3; Clostridiales|Rep: Acetolactate synthase - Dorea longicatena DSM 13814 Length = 564 Score = 41.1 bits (92), Expect = 0.027 Identities = 24/63 (38%), Positives = 33/63 (52%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L +G GTMG G G ++ A + P K V+ + GD F + EI T R+ + Sbjct: 400 PRTLLTSGGLGTMGYGLGASLGAKVG----RPEKTVVNIAGDGCFRMNMNEIATAARHNI 455 Query: 717 PVI 725 PVI Sbjct: 456 PVI 458 >UniRef50_O28264 Cluster: Acetolactate synthase, large subunit; n=1; Archaeoglobus fulgidus|Rep: Acetolactate synthase, large subunit - Archaeoglobus fulgidus Length = 543 Score = 41.1 bits (92), Expect = 0.027 Identities = 24/56 (42%), Positives = 31/56 (55%) Frame = +3 Query: 558 GTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G FG +G G IAA + P KRV V GD +F F+G EI+T R+ L V+ Sbjct: 397 GPFGHLGAGIPMGIAA----KAAYPEKRVFVVTGDGSFLFNGAEIDTAVRHGLQVV 448 >UniRef50_Q89QL7 Cluster: Bll3107 protein; n=2; Proteobacteria|Rep: Bll3107 protein - Bradyrhizobium japonicum Length = 544 Score = 40.7 bits (91), Expect = 0.036 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G+ + AM + P K I V GD+A GF+GM+ ET R ++P++ Sbjct: 413 GYGLGLAMGAKLAKPDKLCINVWGDAAIGFTGMDFETAVRERIPIM 458 >UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme; n=3; Proteobacteria|Rep: Thiamine pyrophosphate-requiring enzyme - Hahella chejuensis (strain KCTC 2396) Length = 591 Score = 40.7 bits (91), Expect = 0.036 Identities = 23/63 (36%), Positives = 32/63 (50%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P LD G FGT+GVG GF + AA G + + GD + +S E +T R+ + Sbjct: 445 PLSWLDPGVFGTLGVGGGFVLGAAA----ATQGVELWLIYGDGSCAYSLAEFDTFVRHNI 500 Query: 717 PVI 725 VI Sbjct: 501 GVI 503 >UniRef50_O28180 Cluster: Acetolactate synthase, large subunit; n=1; Archaeoglobus fulgidus|Rep: Acetolactate synthase, large subunit - Archaeoglobus fulgidus Length = 575 Score = 40.7 bits (91), Expect = 0.036 Identities = 22/65 (33%), Positives = 40/65 (61%), Gaps = 5/65 (7%) Frame = +3 Query: 45 GKGVVADESEYCVSTARTQALL---KADVILLLGARMNWMLHFGQPPRYA-PD-VKIIQV 209 G+G + ++ C+ A A+ +ADVIL++G++M + +G+PP + P+ K IQ+ Sbjct: 248 GRGAIPEDHPLCILPASPAAITAQNEADVILVVGSKMGDLDFWGKPPAWGDPEQQKTIQI 307 Query: 210 EISPE 224 +I PE Sbjct: 308 DIDPE 312 >UniRef50_Q5YN72 Cluster: Putative acetolactate synthase large subunit; n=1; Nocardia farcinica|Rep: Putative acetolactate synthase large subunit - Nocardia farcinica Length = 596 Score = 40.3 bits (90), Expect = 0.047 Identities = 19/47 (40%), Positives = 27/47 (57%) Frame = +3 Query: 582 GPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 G G+A +A+ +A G+R + + GD AF GME+ T Y LPV Sbjct: 455 GMGYAFGSAIGSA-FARGRRTVVIAGDGAFYMHGMEVHTAVEYGLPV 500 >UniRef50_Q3JBM9 Cluster: Acetolactate synthase large subunit; n=1; Nitrosococcus oceani ATCC 19707|Rep: Acetolactate synthase large subunit - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 602 Score = 40.3 bits (90), Expect = 0.047 Identities = 20/46 (43%), Positives = 28/46 (60%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G+AI AA+ APG V+C+ GD ++ SG EI + +LPVI Sbjct: 464 GWAIGAAVGSALGAPGNPVVCITGDGSWLMSGQEITVASQEQLPVI 509 >UniRef50_Q0FGP6 Cluster: Acetolactate synthase II large subunit; n=1; alpha proteobacterium HTCC2255|Rep: Acetolactate synthase II large subunit - alpha proteobacterium HTCC2255 Length = 545 Score = 40.3 bits (90), Expect = 0.047 Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 1/71 (1%) Frame = +3 Query: 516 GLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIE 695 G LN HRL A G MG G + AA+ + P ++VIC GD F S E+ Sbjct: 393 GKYLNYSKEHRLLAPQAGAMGAG----VPAALAAKSIFPNRQVICFAGDGDFQMSSSELG 448 Query: 696 TMFRYKL-PVI 725 T + L P+I Sbjct: 449 TAMQEGLNPII 459 >UniRef50_Q025T6 Cluster: Thiamine pyrophosphate enzyme TPP binding domain protein; n=1; Solibacter usitatus Ellin6076|Rep: Thiamine pyrophosphate enzyme TPP binding domain protein - Solibacter usitatus (strain Ellin6076) Length = 608 Score = 39.9 bits (89), Expect = 0.063 Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Frame = +3 Query: 567 GTMGVGPGFAIAAAMWCRDYAPGKR-VICVEGDSAFGFSGMEIETMFRYKLPV 722 G MG G +I M A G+R V+CV+GD F F+ E+ET+ R +LP+ Sbjct: 430 GAMGYGIAASIGVCM-----ASGRREVVCVDGDGGFQFNIQELETVARLQLPI 477 >UniRef50_A0WA20 Cluster: Thiamine pyrophosphate enzyme-like TPP binding region; n=1; Geobacter lovleyi SZ|Rep: Thiamine pyrophosphate enzyme-like TPP binding region - Geobacter lovleyi SZ Length = 562 Score = 39.9 bits (89), Expect = 0.063 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 GFA+AA + + A + V+ + GD +F +GME+ T Y +PVI Sbjct: 422 GFAVAAPIGAKLAAGDRPVVALVGDGSFLMNGMEVATAVNYNIPVI 467 >UniRef50_A5K231 Cluster: Bi-functional enzyme: long-chain fatty-acid Co-A ligase and oxalyl Co- A decarboxylase, putative; n=1; Plasmodium vivax|Rep: Bi-functional enzyme: long-chain fatty-acid Co-A ligase and oxalyl Co- A decarboxylase, putative - Plasmodium vivax Length = 1314 Score = 39.9 bits (89), Expect = 0.063 Identities = 22/53 (41%), Positives = 31/53 (58%) Frame = +3 Query: 567 GTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G MGV AI A+ R+ V + GDS+FGF+ E+ET+ R+KL V+ Sbjct: 1163 GMMGVSMNAAICGALNDRENV----VFAILGDSSFGFTSNEVETICRFKLKVV 1211 >UniRef50_Q0CI52 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 574 Score = 39.9 bits (89), Expect = 0.063 Identities = 20/56 (35%), Positives = 34/56 (60%) Frame = +3 Query: 558 GTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G G +G G G+A+ AA+ AP ++V+ + GD + GF ME++T R+ L ++ Sbjct: 409 GNLGFLGNGFGYALGAAI----AAPDRKVVNLHGDGSAGFHFMELDTYKRFNLNIM 460 >UniRef50_A4AC84 Cluster: Acetolactate synthase; n=2; cellular organisms|Rep: Acetolactate synthase - Congregibacter litoralis KT71 Length = 619 Score = 39.5 bits (88), Expect = 0.083 Identities = 22/65 (33%), Positives = 35/65 (53%) Frame = +3 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFR 707 + PR L + FGTMG G + AA+ + AP ++VI ++GD + + E+ T R Sbjct: 432 SKQPRSFLSSSGFGTMGYG----LPAAIGAKIAAPDRQVIDIDGDGSLNMTIHELSTCHR 487 Query: 708 YKLPV 722 Y + V Sbjct: 488 YGIGV 492 >UniRef50_A1SCQ1 Cluster: Thiamine pyrophosphate enzyme domain protein TPP-binding; n=2; Actinobacteria (class)|Rep: Thiamine pyrophosphate enzyme domain protein TPP-binding - Nocardioides sp. (strain BAA-499 / JS614) Length = 543 Score = 39.5 bits (88), Expect = 0.083 Identities = 17/45 (37%), Positives = 27/45 (60%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 G+A+ A+ + +P + V+ V GD F +G E+ET RY LP+ Sbjct: 407 GYAVPGAVGAKAASPDRHVLGVVGDGGFLMTGSEVETAVRYGLPL 451 >UniRef50_Q7WCV8 Cluster: Putative acetolactate synthase large subunit; n=7; Proteobacteria|Rep: Putative acetolactate synthase large subunit - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 596 Score = 39.1 bits (87), Expect = 0.11 Identities = 17/47 (36%), Positives = 27/47 (57%) Frame = +3 Query: 582 GPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 G G+ + A+ + PG RVIC+ GD F E+ET R+++P+ Sbjct: 452 GLGWGVPMAIGAKIARPGARVICLTGDGGFAHCWAELETARRHEVPL 498 >UniRef50_Q2S0N1 Cluster: Acetolactate synthase, large subunit, biosynthetic type; n=1; Salinibacter ruber DSM 13855|Rep: Acetolactate synthase, large subunit, biosynthetic type - Salinibacter ruber (strain DSM 13855) Length = 596 Score = 39.1 bits (87), Expect = 0.11 Identities = 20/61 (32%), Positives = 30/61 (49%) Frame = +3 Query: 540 RHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLP 719 R + +G GTMG G A+ AA R+ ++CV GD F + E+ R+ LP Sbjct: 427 RSHISSGGLGTMGFGLPAAMGAAFGMRE-GRNLDIVCVSGDGGFVMNAQELSVAARHGLP 485 Query: 720 V 722 + Sbjct: 486 L 486 >UniRef50_Q18S72 Cluster: Thiamine pyrophosphate enzyme-like TPP binding region; n=2; Desulfitobacterium hafniense|Rep: Thiamine pyrophosphate enzyme-like TPP binding region - Desulfitobacterium hafniense (strain DCB-2) Length = 591 Score = 39.1 bits (87), Expect = 0.11 Identities = 22/63 (34%), Positives = 35/63 (55%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L G GTMG G G A+ A + P ++V+ + GD++ G S E+ T ++ + Sbjct: 428 PRSFLITGRAGTMGWGLGAALGAKL----AYPDRQVVNLLGDASLGMSLQELATAAKHNI 483 Query: 717 PVI 725 PV+ Sbjct: 484 PVV 486 >UniRef50_A2QFR5 Cluster: Acetolactate synthase; n=3; Aspergillus|Rep: Acetolactate synthase - Aspergillus niger Length = 645 Score = 39.1 bits (87), Expect = 0.11 Identities = 20/63 (31%), Positives = 36/63 (57%) Frame = +3 Query: 534 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYK 713 H R + +G GTMG G ++AA+ + P +V+C++GD++F S E+ T ++ Sbjct: 491 HERFLVTSGGLGTMGYG----LSAAIGSKTARPSNQVVCIDGDASFCMSMEELLTASQHG 546 Query: 714 LPV 722 + V Sbjct: 547 VAV 549 >UniRef50_Q8EP38 Cluster: Acetolactate synthase large subunit; n=4; Bacillaceae|Rep: Acetolactate synthase large subunit - Oceanobacillus iheyensis Length = 556 Score = 38.7 bits (86), Expect = 0.14 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +3 Query: 561 TFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 T G MG G AI AA+ +P K VI + GD F + E+ET RYK+ ++ Sbjct: 414 TSGAMGYGVPSAIGAAI----ASPHKTVIALSGDGGFMMTAQELETAVRYKVGML 464 >UniRef50_Q2AIK5 Cluster: Thiamine pyrophosphate enzyme, C-terminal TPP-binding:Thiamine pyrophosphate enzyme, central region:Thiamine pyrophosphate enzyme, N- terminal TPP binding region; n=1; Halothermothrix orenii H 168|Rep: Thiamine pyrophosphate enzyme, C-terminal TPP-binding:Thiamine pyrophosphate enzyme, central region:Thiamine pyrophosphate enzyme, N- terminal TPP binding region - Halothermothrix orenii H 168 Length = 534 Score = 38.7 bits (86), Expect = 0.14 Identities = 23/69 (33%), Positives = 32/69 (46%) Frame = +3 Query: 516 GLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIE 695 G N H L +GT+ TMG F++ +A+ R P +V + GD EI Sbjct: 386 GRYFGNKCAHTLISGTWRTMG----FSLPSALAARINKPNNQVTSIIGDGGLSMVLAEIS 441 Query: 696 TMFRYKLPV 722 T RY LP+ Sbjct: 442 TAVRYNLPI 450 >UniRef50_Q6LF61 Cluster: Putative bi-functional enzyme: long-chain fatty-acid Co-A ligase and oxalyl Co-A decarboxylase; n=1; Plasmodium falciparum 3D7|Rep: Putative bi-functional enzyme: long-chain fatty-acid Co-A ligase and oxalyl Co-A decarboxylase - Plasmodium falciparum (isolate 3D7) Length = 1392 Score = 38.7 bits (86), Expect = 0.14 Identities = 21/53 (39%), Positives = 31/53 (58%) Frame = +3 Query: 567 GTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G MGV +I+AA+ P + + GDS+FGF+ EIET+ R KL ++ Sbjct: 1235 GMMGVSMNASISAAL----DNPNNIIFSILGDSSFGFTSNEIETICRLKLKIV 1283 >UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular organisms|Rep: Acetolactate synthase - Desulfotalea psychrophila Length = 612 Score = 38.3 bits (85), Expect = 0.19 Identities = 23/56 (41%), Positives = 29/56 (51%) Frame = +3 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 NHPRH + +G GTMG G AI A M P K VI + GD + + E+ T Sbjct: 455 NHPRHFVTSGGLGTMGFGLPAAIGAQM----AFPDKIVIDIAGDGSIQMNIQELAT 506 >UniRef50_Q3XZD0 Cluster: Pyruvate decarboxylase; n=3; Lactobacillales|Rep: Pyruvate decarboxylase - Enterococcus faecium DO Length = 576 Score = 38.3 bits (85), Expect = 0.19 Identities = 26/71 (36%), Positives = 36/71 (50%) Frame = +3 Query: 513 RGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEI 692 R L +N +H +G F TMG G IAA + Y P K+V + GD F +I Sbjct: 392 RLLNMNGKQKHTT-SGWFATMGNGVPGGIAAQL---SY-PEKQVFTLSGDGGFAMVMQDI 446 Query: 693 ETMFRYKLPVI 725 T +Y+LP+I Sbjct: 447 ITQVKYQLPII 457 >UniRef50_A1WXE6 Cluster: Acetolactate synthase; n=6; Proteobacteria|Rep: Acetolactate synthase - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 628 Score = 38.3 bits (85), Expect = 0.19 Identities = 25/62 (40%), Positives = 32/62 (51%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L +G GTMG G AI A + P + VI V+GD + + E+ET Y L Sbjct: 446 PRQWLTSGGLGTMGFGLPAAIGAYLG----RPDRVVIDVDGDGSLRMNLGELETATTYNL 501 Query: 717 PV 722 PV Sbjct: 502 PV 503 >UniRef50_A0W3U9 Cluster: Thiamine pyrophosphate enzyme-like TPP binding region; n=1; Geobacter lovleyi SZ|Rep: Thiamine pyrophosphate enzyme-like TPP binding region - Geobacter lovleyi SZ Length = 550 Score = 38.3 bits (85), Expect = 0.19 Identities = 15/46 (32%), Positives = 26/46 (56%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G+ AA+ R PG+R + + GD AF + E+ T+ R ++P + Sbjct: 412 GYCTPAALGARLARPGRRPVVMTGDGAFQMTAQEVSTLVRLQIPAV 457 >UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzymes; n=2; Trichocomaceae|Rep: Thiamine pyrophosphate-requiring enzymes - Aspergillus oryzae Length = 597 Score = 38.3 bits (85), Expect = 0.19 Identities = 20/57 (35%), Positives = 34/57 (59%) Frame = +3 Query: 555 AGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 +G G +G G G+A+ AA+ C P + VI + GD + GF M+++T R+ L ++ Sbjct: 430 SGGLGFLGNGFGYALGAAVAC----PDQTVINLHGDGSAGFHFMDLDTYKRHNLNIM 482 >UniRef50_Q11NN4 Cluster: Acetolactate synthase, large subunit; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Acetolactate synthase, large subunit - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 573 Score = 37.9 bits (84), Expect = 0.25 Identities = 22/62 (35%), Positives = 31/62 (50%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P H L +G G+MG F + AAM + P V C+ GD +F + E+ T + K Sbjct: 408 PNHFLTSGGLGSMG----FGLPAAMGAQAALPFNDVWCITGDGSFQMNMQEMVTCVQEKW 463 Query: 717 PV 722 PV Sbjct: 464 PV 465 >UniRef50_A1R2T4 Cluster: Putative acetolactate synthase, large subunit; n=2; Micrococcineae|Rep: Putative acetolactate synthase, large subunit - Arthrobacter aurescens (strain TC1) Length = 539 Score = 37.9 bits (84), Expect = 0.25 Identities = 23/62 (37%), Positives = 34/62 (54%) Frame = +3 Query: 525 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 L+++ + L A G MG+G A+AA++ PG++VI V GD F +G EI T Sbjct: 391 LDHNSANSLAAPRNGAMGMGIPAAVAASL----AYPGRQVISVAGDGCFMMNGQEIATAM 446 Query: 705 RY 710 Y Sbjct: 447 GY 448 >UniRef50_Q8U2A4 Cluster: Acetolactate synthase; n=4; cellular organisms|Rep: Acetolactate synthase - Pyrococcus furiosus Length = 564 Score = 37.9 bits (84), Expect = 0.25 Identities = 24/63 (38%), Positives = 31/63 (49%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L +G GTMG F AA+ + P K V+ + GD +F S E+ T L Sbjct: 408 PRTFLTSGGLGTMG----FGFPAAIGAKVAKPEKVVVDIAGDGSFMMSERELATAVNENL 463 Query: 717 PVI 725 PVI Sbjct: 464 PVI 466 Score = 33.5 bits (73), Expect = 5.4 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 7/82 (8%) Frame = +3 Query: 21 LPFLPTPMGKGVVADESEYCVST-------ARTQALLKADVILLLGARMNWMLHFGQPPR 179 +P + T MGKG V + V A + L + D+I+ +G R + + Sbjct: 234 IPIMATFMGKGAVPENHPLYVGNLGMHGKIAANKLLPQTDLIIAVGMRWSDRT-VSEFEN 292 Query: 180 YAPDVKIIQVEISPEEFHNSKK 245 +AP+ KII ++I P+E + K Sbjct: 293 FAPEAKIIHIDIDPKEVGKNVK 314 >UniRef50_Q2NI87 Cluster: Acetolactate synthase; n=2; Methanosphaera stadtmanae DSM 3091|Rep: Acetolactate synthase - Methanosphaera stadtmanae (strain DSM 3091) Length = 562 Score = 37.9 bits (84), Expect = 0.25 Identities = 21/64 (32%), Positives = 32/64 (50%) Frame = +3 Query: 534 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYK 713 +PR + +G GTMG F + AAM + P + V+ V GD F E+ T+ Sbjct: 398 NPRTFISSGGLGTMG----FGLPAAMGAQVAKPEENVLAVVGDGGFQMVSQELATIKEND 453 Query: 714 LPVI 725 LP++ Sbjct: 454 LPIV 457 >UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large subunit; n=49; Bacteria|Rep: Acetolactate synthase isozyme 1 large subunit - Escherichia coli (strain K12) Length = 562 Score = 37.9 bits (84), Expect = 0.25 Identities = 23/64 (35%), Positives = 32/64 (50%) Frame = +3 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 N PR L +G GTMG G AI AA+ P ++V+C GD + + E+ T Sbjct: 405 NRPRQWLTSGGLGTMGFGLPAAIGAAL----ANPDRKVLCFSGDGSLMMNIQEMATASEN 460 Query: 711 KLPV 722 +L V Sbjct: 461 QLDV 464 >UniRef50_Q1IPP8 Cluster: Thiamine pyrophosphate enzyme-like TPP-binding; n=2; cellular organisms|Rep: Thiamine pyrophosphate enzyme-like TPP-binding - Acidobacteria bacterium (strain Ellin345) Length = 584 Score = 37.5 bits (83), Expect = 0.33 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = +3 Query: 555 AGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 +GT TM G ++I A++ PG++V+C+ GD E T+ +YKLPV Sbjct: 412 SGTLATMANGLPYSIGASV----AHPGRQVVCIIGDGGLTMLMGEPATLVKYKLPV 463 >UniRef50_P00892 Cluster: Acetolactate synthase isozyme 2 large subunit; n=134; Proteobacteria|Rep: Acetolactate synthase isozyme 2 large subunit - Escherichia coli (strain K12) Length = 548 Score = 37.5 bits (83), Expect = 0.33 Identities = 19/67 (28%), Positives = 35/67 (52%) Frame = +3 Query: 522 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETM 701 + + P + + + GTMG F + AA+ + P V+C+ GD +F + E+ T+ Sbjct: 386 IAHTRPENFITSSGLGTMG----FGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTV 441 Query: 702 FRYKLPV 722 R +LP+ Sbjct: 442 KRKQLPL 448 >UniRef50_Q988P8 Cluster: Acetolactate synthase, large subunit; n=6; Bacteria|Rep: Acetolactate synthase, large subunit - Rhizobium loti (Mesorhizobium loti) Length = 600 Score = 37.1 bits (82), Expect = 0.44 Identities = 21/63 (33%), Positives = 33/63 (52%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L +G+F MG +A+ AAM + P ++V+ + GD F S E+ T + Sbjct: 422 PRTHLTSGSFSPMG----WAVPAAMGAKLAMPDRQVVSITGDGDFMMSLPELGTAVMNNI 477 Query: 717 PVI 725 PV+ Sbjct: 478 PVV 480 >UniRef50_Q8F341 Cluster: Acetolactate synthase large subunit; n=5; Bacteria|Rep: Acetolactate synthase large subunit - Leptospira interrogans Length = 592 Score = 37.1 bits (82), Expect = 0.44 Identities = 22/66 (33%), Positives = 33/66 (50%) Frame = +3 Query: 525 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 L + P + L +G GTMG G + AA+ + P K IC+ GD + + E+ T+ Sbjct: 424 LMDEPNNWLTSGGLGTMGYG----LPAAIGAKFGRPDKTTICISGDGSIQMNIQELATIV 479 Query: 705 RYKLPV 722 KL V Sbjct: 480 ANKLGV 485 >UniRef50_Q64QU8 Cluster: Pyruvate dehydrogenase; n=6; Bacteroidetes|Rep: Pyruvate dehydrogenase - Bacteroides fragilis Length = 579 Score = 37.1 bits (82), Expect = 0.44 Identities = 23/72 (31%), Positives = 36/72 (50%) Frame = +3 Query: 507 YGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGM 686 +G L RH L + G+M AI AA+ C P ++VI + GD + Sbjct: 388 WGARYLQATGKRHMLGSFNHGSMANALPQAIGAALAC----PDRQVIALCGDGGLSMTLG 443 Query: 687 EIETMFRYKLPV 722 ++ET+ +YKLP+ Sbjct: 444 DLETVVQYKLPI 455 >UniRef50_Q70I04 Cluster: Putative acetolactate synthase; n=1; Streptomyces parvulus|Rep: Putative acetolactate synthase - Streptomyces parvulus Length = 539 Score = 37.1 bits (82), Expect = 0.44 Identities = 22/63 (34%), Positives = 30/63 (47%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P H G FG++G+G AI AA G+ V+ GD F E T RY+L Sbjct: 399 PLHFTVMGGFGSIGLGVAGAIGAAT----AGTGRPVVAAVGDGGFMMHLSEFTTAVRYRL 454 Query: 717 PVI 725 P++ Sbjct: 455 PLV 457 >UniRef50_Q1M4Y3 Cluster: Putative thiamine pyrophosphate requiring enzyme; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative thiamine pyrophosphate requiring enzyme - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 563 Score = 37.1 bits (82), Expect = 0.44 Identities = 23/67 (34%), Positives = 34/67 (50%) Frame = +3 Query: 525 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 L + P + G +G G GFA+ A + P V+ + G+SAFG G++ ET Sbjct: 416 LASTPGSYIGWGKTTQLGSGLGFAMGARL----ARPDATVVNLMGESAFGMVGIDFETAV 471 Query: 705 RYKLPVI 725 R LPV+ Sbjct: 472 RCNLPVL 478 >UniRef50_A6LX01 Cluster: Thiamine pyrophosphate protein, central region; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Thiamine pyrophosphate protein, central region - Clostridium beijerinckii NCIMB 8052 Length = 543 Score = 37.1 bits (82), Expect = 0.44 Identities = 19/53 (35%), Positives = 27/53 (50%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 FG MG G++I A + +Y R++C+ GD G EI T Y +PV Sbjct: 408 FGAMGHAIGYSIGAQL--ANY--NSRIVCITGDGCTFMQGAEISTAANYNIPV 456 >UniRef50_A6G7M7 Cluster: Acetolactate synthase large subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Acetolactate synthase large subunit - Plesiocystis pacifica SIR-1 Length = 562 Score = 37.1 bits (82), Expect = 0.44 Identities = 17/55 (30%), Positives = 30/55 (54%) Frame = +3 Query: 561 TFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 ++G G+G G A M Y ++V+C+ GD +G E+ T RY++P++ Sbjct: 419 SYGLGGMGSGLGTAIGMQLA-YGYLRQVVCMIGDGGLLMTGSELATCVRYQIPLV 472 >UniRef50_Q84H41 Cluster: Sulfoacetaldehyde acetyltransferase; n=28; Bacteria|Rep: Sulfoacetaldehyde acetyltransferase - Alcaligenes xylosoxydans xylosoxydans (Achromobacter xylosoxidans) Length = 603 Score = 37.1 bits (82), Expect = 0.44 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 1/66 (1%) Frame = +3 Query: 528 NNHPRHRLDAGTFGTMGVGP-GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 N++ R F M G G+A+ + + AP + I GD A+G S MEI T Sbjct: 432 NSYLRFDEPRSFFAPMSFGNCGYALPTIIGAKCAAPDRPAIAYAGDGAWGMSMMEIMTAV 491 Query: 705 RYKLPV 722 R+ +PV Sbjct: 492 RHDIPV 497 >UniRef50_Q8TR30 Cluster: Acetolactate synthase, large subunit; n=4; cellular organisms|Rep: Acetolactate synthase, large subunit - Methanosarcina acetivorans Length = 548 Score = 36.7 bits (81), Expect = 0.58 Identities = 18/49 (36%), Positives = 29/49 (59%) Frame = +3 Query: 579 VGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 +G GF+ A + + P +RV+ V GD F + E+ET RYK+P++ Sbjct: 409 MGAGFS--AGLVAKLLHPERRVLAVCGDGGFMMNCQELETAIRYKIPLV 455 >UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large subunit; n=5; Bacteria|Rep: Acetolactate synthase isozyme I large subunit - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 554 Score = 36.3 bits (80), Expect = 0.77 Identities = 21/54 (38%), Positives = 28/54 (51%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 PR L +G FGTMG G AI AA+ P + V+C GD + + E+ T Sbjct: 399 PRQWLTSGGFGTMGFGLPAAIGAAL----AEPDRTVVCFSGDGSLMMNIQEMAT 448 >UniRef50_Q13H77 Cluster: Putative pyruvate decarboxylase; n=1; Burkholderia xenovorans LB400|Rep: Putative pyruvate decarboxylase - Burkholderia xenovorans (strain LB400) Length = 561 Score = 36.3 bits (80), Expect = 0.77 Identities = 23/63 (36%), Positives = 32/63 (50%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR RL A G MG G AIA + PG++ +C+ GD F +G EI +L Sbjct: 421 PR-RLMAPLSGAMGYGVPSAIATQL----RYPGQKTVCLVGDGGFLMTGNEIIAAVERRL 475 Query: 717 PVI 725 P++ Sbjct: 476 PIL 478 >UniRef50_A6NPM8 Cluster: Acetolactate synthase; n=2; Bacteria|Rep: Acetolactate synthase - Bacteroides capillosus ATCC 29799 Length = 568 Score = 36.3 bits (80), Expect = 0.77 Identities = 23/65 (35%), Positives = 31/65 (47%) Frame = +3 Query: 531 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 + P + +G FGTMG G G AAM + P V GD F + E+ T+ Y Sbjct: 411 DRPGQLVTSGGFGTMGFGLG----AAMGAKMGNPDTPVFLCTGDGCFRMNCHELCTLEHY 466 Query: 711 KLPVI 725 +PVI Sbjct: 467 NIPVI 471 >UniRef50_A3GGL8 Cluster: Pyruvate decarboxylase; n=5; Saccharomycetales|Rep: Pyruvate decarboxylase - Pichia stipitis (Yeast) Length = 596 Score = 36.3 bits (80), Expect = 0.77 Identities = 17/49 (34%), Positives = 26/49 (53%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRY 710 +G++G G + AAM ++ P KR I GD + + EI TM R+ Sbjct: 445 WGSIGFSVGATLGAAMAAQELDPNKRTILFVGDGSLQLTVQEISTMIRW 493 >UniRef50_P37063 Cluster: Pyruvate oxidase; n=2; Lactobacillus plantarum|Rep: Pyruvate oxidase - Lactobacillus plantarum Length = 603 Score = 36.3 bits (80), Expect = 0.77 Identities = 26/71 (36%), Positives = 37/71 (52%) Frame = +3 Query: 513 RGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEI 692 R L L RH + + F TMGVG AIAA + +Y P ++V + GD + ++ Sbjct: 403 RHLKLTPSNRH-ITSNLFATMGVGIPGAIAAKL---NY-PERQVFNLAGDGGASMTMQDL 457 Query: 693 ETMFRYKLPVI 725 T +Y LPVI Sbjct: 458 ATQVQYHLPVI 468 >UniRef50_Q9RU76 Cluster: Acetolactate synthase; n=3; Bacteria|Rep: Acetolactate synthase - Deinococcus radiodurans Length = 592 Score = 35.9 bits (79), Expect = 1.0 Identities = 22/60 (36%), Positives = 30/60 (50%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR L++G GTMG G AI AA+ PG + V GD F + E+ T+ Y + Sbjct: 402 PRRWLNSGGLGTMGFGFPAAIGAAL----AEPGVVSMVVAGDGGFQMTAQELATLKMYDI 457 >UniRef50_Q8ELJ0 Cluster: Acetolactate synthase large subunit; n=4; Bacteria|Rep: Acetolactate synthase large subunit - Oceanobacillus iheyensis Length = 586 Score = 35.9 bits (79), Expect = 1.0 Identities = 58/249 (23%), Positives = 90/249 (36%), Gaps = 14/249 (5%) Frame = +3 Query: 21 LPFLPTPMGKGVVADESEYCVSTAR-------TQALLKADVILLLGARMNWMLHFGQPPR 179 +P T MGKGV+ D++E + + AD I LG + P Sbjct: 238 IPVAHTLMGKGVIPDDNELVLGMTGFWGTKFINEKTRTADQIFALGTQFAEADSSSWEPE 297 Query: 180 YA---PDVKIIQVEISPEEFHNSKKSEXXXXXXXXXXXXXXXXG----CPKGSSHCNLKT 338 Y PD K+IQ++I P E + E P G S+ +K Sbjct: 298 YTFNIPDTKLIQIDIDPNEIGRNYPVEIGVVADLKEALTVLNRVAKEIAPDGVSNSKIKE 357 Query: 339 TVGGRD*NRTKSKHRICRGSSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRG 518 + T+S S+ S +L ++ R + + +G G+ Sbjct: 358 EIKNYRKEFTQSNLEASE-SNSYPLSPQRILADVRSVIPRDA--YITTDVGWNKNGVGQQ 414 Query: 519 LLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 + P L G + TMG G A+ A + +D K VI + GD FG + + T Sbjct: 415 FPI-YEPGSILTPGGYATMGFGAPAAMGAKIAKKD----KVVISLVGDGGFGQNPALLAT 469 Query: 699 MFRYKLPVI 725 +PVI Sbjct: 470 AVEENIPVI 478 >UniRef50_A6G882 Cluster: Acetolactate synthase large subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Acetolactate synthase large subunit - Plesiocystis pacifica SIR-1 Length = 639 Score = 35.9 bits (79), Expect = 1.0 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +3 Query: 507 YGRGLLLNNHP-RHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSG 683 +G LL + P R+R+ G FG+MG I AA+ PG++ + + GD A Sbjct: 472 WGNHLLRFDEPNRYRVSTG-FGSMGHAVTGVIGAAL----AEPGRKAVAIAGDGAM-LMN 525 Query: 684 MEIETMFRYKLPVI 725 EI T +Y LP + Sbjct: 526 SEISTAVQYGLPAV 539 >UniRef50_A5ZRI3 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 622 Score = 35.9 bits (79), Expect = 1.0 Identities = 16/45 (35%), Positives = 27/45 (60%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 GF + AA PGK V+CV G+ + + E++T+++ +LPV Sbjct: 448 GFCLPAATGICVAQPGKPVVCVTGEGSLQMNLQELQTIWQNRLPV 492 >UniRef50_A0KE44 Cluster: Thiamine pyrophosphate enzyme domain protein TPP-binding; n=3; Burkholderia cenocepacia|Rep: Thiamine pyrophosphate enzyme domain protein TPP-binding - Burkholderia cenocepacia (strain HI2424) Length = 526 Score = 35.9 bits (79), Expect = 1.0 Identities = 19/62 (30%), Positives = 33/62 (53%) Frame = +3 Query: 540 RHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLP 719 RH + T G +G G A+ AA+ C P +RV ++ D + ++ + TM R +LP Sbjct: 386 RHTILTNTGGAIGQGLPVALGAAVAC----PDRRVFALQSDGSAQYTIQSLWTMARERLP 441 Query: 720 VI 725 ++ Sbjct: 442 IV 443 >UniRef50_O01535 Cluster: Seven tm receptor protein 136; n=2; Caenorhabditis elegans|Rep: Seven tm receptor protein 136 - Caenorhabditis elegans Length = 347 Score = 35.9 bits (79), Expect = 1.0 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 4/58 (6%) Frame = -1 Query: 181 YLGGCPKCSIQF--ILAPRSSMT--SAFSRACVRAVDTQYSDSSATTPLPIGVGKKGN 20 YLG CS+ ++ P +MT SAF RA + AV +S S T LP+ V K N Sbjct: 285 YLGNLTSCSLAVYPVIEPIIAMTCISAFRRATINAVTCSHSVSPTTAVLPVLVSKYRN 342 >UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5; Lactobacillaceae|Rep: Pyruvate oxidase - Lactobacillus plantarum Length = 585 Score = 35.5 bits (78), Expect = 1.3 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Frame = +3 Query: 525 LNNHPRHRL-DAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETM 701 L +P+ +L + F TMG G AIAA M Y P ++ + GD AF ++ T Sbjct: 398 LKMNPKQKLLTSALFATMGAGVPGAIAAKM---SY-PDRQAFNIAGDGAFSMVMQDLLTE 453 Query: 702 FRYKLPV 722 +Y LP+ Sbjct: 454 VKYHLPI 460 >UniRef50_Q39P46 Cluster: Acetolactate synthase, large subunit; n=15; Proteobacteria|Rep: Acetolactate synthase, large subunit - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 564 Score = 35.5 bits (78), Expect = 1.3 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Frame = +3 Query: 537 PRHRLDAGT-FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYK 713 PR ++ T +GT+G G AI A + AP + V+C+ GD F+ E+ + + Sbjct: 423 PRSWFNSSTGYGTLGYGLPAAIGAKL----AAPARPVVCLIGDGGLQFTLPELASAVEAR 478 Query: 714 LPVI 725 LPVI Sbjct: 479 LPVI 482 >UniRef50_Q04D18 Cluster: Thiamine pyrophosphate-requiring enzyme (Acetolactate synthase, pyruvate dehydrogenase (Cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase); n=3; Lactobacillales|Rep: Thiamine pyrophosphate-requiring enzyme (Acetolactate synthase, pyruvate dehydrogenase (Cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase) - Oenococcus oeni (strain BAA-331 / PSU-1) Length = 578 Score = 35.5 bits (78), Expect = 1.3 Identities = 21/53 (39%), Positives = 28/53 (52%) Frame = +3 Query: 567 GTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 GTMG G AIA + P +RV+ + GD AF + T +YKLP+I Sbjct: 410 GTMGCGLPGAIAGQI----VFPKRRVLSLIGDGAFSMVMQDFVTAVKYKLPII 458 >UniRef50_A6DLM5 Cluster: Acetolactate synthase; n=1; Lentisphaera araneosa HTCC2155|Rep: Acetolactate synthase - Lentisphaera araneosa HTCC2155 Length = 569 Score = 35.5 bits (78), Expect = 1.3 Identities = 21/58 (36%), Positives = 29/58 (50%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 L +G GTMG F AA+ + PG V+ V GD F + E+ T +KLP+ Sbjct: 404 LSSGGAGTMG----FGFPAAIGAQFGRPGDLVVSVSGDGGFQMTLFELSTAAIHKLPI 457 >UniRef50_Q7RCT1 Cluster: Peroxisomal-coenzyme a synthetase; n=5; Plasmodium (Vinckeia)|Rep: Peroxisomal-coenzyme a synthetase - Plasmodium yoelii yoelii Length = 1377 Score = 35.5 bits (78), Expect = 1.3 Identities = 20/53 (37%), Positives = 32/53 (60%) Frame = +3 Query: 567 GTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G MGV AI+A++ ++ + + GDS+FGF+ EIET+ R KL ++ Sbjct: 1217 GMMGVSMNAAISASLENKNNI----IFSILGDSSFGFTCNEIETICRLKLKIV 1265 >UniRef50_P06672 Cluster: Pyruvate decarboxylase; n=8; cellular organisms|Rep: Pyruvate decarboxylase - Zymomonas mobilis Length = 568 Score = 35.5 bits (78), Expect = 1.3 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G+++ AA AP +R I + GD +F + E+ M R KLPVI Sbjct: 416 GWSVPAAFGYAVGAPERRNILMVGDGSFQLTAQEVAQMVRLKLPVI 461 >UniRef50_P26263 Cluster: Pyruvate decarboxylase isozyme 3; n=26; Ascomycota|Rep: Pyruvate decarboxylase isozyme 3 - Saccharomyces cerevisiae (Baker's yeast) Length = 563 Score = 35.5 bits (78), Expect = 1.3 Identities = 18/51 (35%), Positives = 26/51 (50%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 +G++G G + AA + P KRVI GD + + EI TM R+ L Sbjct: 412 WGSIGFTTGATLGAAFAAEEIDPNKRVILFIGDGSLQLTVQEISTMIRWGL 462 >UniRef50_Q88YC4 Cluster: Pyruvate oxidase; n=5; Lactobacillales|Rep: Pyruvate oxidase - Lactobacillus plantarum Length = 587 Score = 35.1 bits (77), Expect = 1.8 Identities = 25/71 (35%), Positives = 32/71 (45%) Frame = +3 Query: 513 RGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEI 692 RGL ++ R L +G F TMG G +A A+ P + GD F +I Sbjct: 393 RGLPMDQEQRFAL-SGLFATMGFGLPAGMAGAL----SVPDSQAWSFSGDGGFAMVAPDI 447 Query: 693 ETMFRYKLPVI 725 T RY LPVI Sbjct: 448 ITEARYGLPVI 458 >UniRef50_Q3A0L4 Cluster: Pyruvate decarboxylase; n=3; Bacteria|Rep: Pyruvate decarboxylase - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 547 Score = 35.1 bits (77), Expect = 1.8 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 GFA+ A+ + P R + + GD AF +GMEI T R+ L P++ Sbjct: 408 GFAVPGAIGAQLARPDLRPLVLVGDGAFQMTGMEISTAARFGLSPIV 454 >UniRef50_Q6JHM8 Cluster: Acetolactate synthase; n=1; Saccharopolyspora spinosa|Rep: Acetolactate synthase - Saccharopolyspora spinosa Length = 533 Score = 35.1 bits (77), Expect = 1.8 Identities = 17/45 (37%), Positives = 24/45 (53%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 GFA+ AA+ P +R++C GD G E+ET+ R L V Sbjct: 398 GFAVPAAVAAALARPSRRIVCFTGDGGLGMCLGELETISRLGLNV 442 >UniRef50_A6X6D0 Cluster: Thiamine pyrophosphate protein central region; n=2; Rhizobiales|Rep: Thiamine pyrophosphate protein central region - Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) Length = 583 Score = 35.1 bits (77), Expect = 1.8 Identities = 18/50 (36%), Positives = 26/50 (52%) Frame = +3 Query: 576 GVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G+G W D P KR I + GD +FG + E+ET+ R ++P I Sbjct: 429 GLGSALPATVGAWRAD--PDKRPIGLFGDGSFGMTVGELETLVRLQVPAI 476 >UniRef50_A5V6Y6 Cluster: Thiamine pyrophosphate enzyme domain protein TPP-binding; n=4; Alphaproteobacteria|Rep: Thiamine pyrophosphate enzyme domain protein TPP-binding - Sphingomonas wittichii RW1 Length = 547 Score = 35.1 bits (77), Expect = 1.8 Identities = 19/63 (30%), Positives = 32/63 (50%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PRH + G GT+G G A A+ + P K V+ + GD F F+ E+ T ++ + Sbjct: 392 PRHLITCGYQGTLGYG----YATALGVKAAHPDKAVVNIAGDGGFLFTANEMATAAQHGI 447 Query: 717 PVI 725 ++ Sbjct: 448 ALV 450 >UniRef50_A5MZ19 Cluster: Acetolactate synthase; n=1; Clostridium kluyveri DSM 555|Rep: Acetolactate synthase - Clostridium kluyveri DSM 555 Length = 569 Score = 35.1 bits (77), Expect = 1.8 Identities = 23/63 (36%), Positives = 31/63 (49%) Frame = +3 Query: 534 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYK 713 + R L +G G MG G AIAA +D +VI + GD +F + E+ T Y Sbjct: 411 YTRTNLTSGGLGNMGYGLPAAIAAKYAKKD----AQVINITGDGSFQMNMQELGTAVAYN 466 Query: 714 LPV 722 LPV Sbjct: 467 LPV 469 >UniRef50_Q60A74 Cluster: Decarboxylase, thiamine pyrophosphate enzyme family; n=1; Methylococcus capsulatus|Rep: Decarboxylase, thiamine pyrophosphate enzyme family - Methylococcus capsulatus Length = 549 Score = 34.7 bits (76), Expect = 2.4 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Frame = +3 Query: 525 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMF 704 L H R A F T GFA+ AA+ + P R + + GD AF +G E+ T Sbjct: 392 LRVHERSEFLASAFYT---SMGFAVPAALGAQIARPDHRALILVGDGAFQMTGTELSTHA 448 Query: 705 RYKL-PVI 725 R L P++ Sbjct: 449 RLGLAPIV 456 >UniRef50_O68497 Cluster: Catabolic acetolactate synthase; n=11; Bacteria|Rep: Catabolic acetolactate synthase - Clostridium acetobutylicum Length = 563 Score = 34.7 bits (76), Expect = 2.4 Identities = 16/46 (34%), Positives = 23/46 (50%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G AI A+ + P K+V+ V GD F + E+ET R P + Sbjct: 429 GIAIPGALAAKLVNPDKKVVAVTGDGGFMMNSQELETALRIGTPFV 474 >UniRef50_Q28MM5 Cluster: Thiamine pyrophosphate enzyme-like TPP binding protein; n=4; Bacteria|Rep: Thiamine pyrophosphate enzyme-like TPP binding protein - Jannaschia sp. (strain CCS1) Length = 656 Score = 34.7 bits (76), Expect = 2.4 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +3 Query: 507 YGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAP--GKRVICVEGDSAFGFS 680 Y G + L +G G++G A+ A +D A G++VI + GD FG Sbjct: 504 YSFGRYFETKGQRVLMSGYLGSIGFSLPAALGAWAATQDIADLKGRKVISISGDGGFGQY 563 Query: 681 GMEIETMFRYKLPV 722 ME+ T +Y + + Sbjct: 564 AMELTTAVKYGMDI 577 >UniRef50_Q1YQE9 Cluster: Acetolactate synthase, large subunit; n=1; gamma proteobacterium HTCC2207|Rep: Acetolactate synthase, large subunit - gamma proteobacterium HTCC2207 Length = 579 Score = 34.7 bits (76), Expect = 2.4 Identities = 24/69 (34%), Positives = 32/69 (46%) Frame = +3 Query: 519 LLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 LL N+PR + +F MG + I A + P K+V+ + GD A SGME T Sbjct: 400 LLPINNPRSFISPSSFNAMG----YCIPAVNAAKLVNPDKQVVGIVGDGAMLMSGMEALT 455 Query: 699 MFRYKLPVI 725 R L I Sbjct: 456 AVRENLGAI 464 >UniRef50_Q1AVS4 Cluster: Thiamine pyrophosphate enzyme-like TPP binding region; n=2; Rubrobacter xylanophilus DSM 9941|Rep: Thiamine pyrophosphate enzyme-like TPP binding region - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 542 Score = 34.7 bits (76), Expect = 2.4 Identities = 19/68 (27%), Positives = 32/68 (47%) Frame = +3 Query: 522 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETM 701 LL+ + R R G + G GF ++AA+ P + V+CV GD + + + + Sbjct: 390 LLHRYIRVRRPGGFYSAASGGLGFGVSAAVGLSIADPERPVVCVVGDGSLAYGLQALWSA 449 Query: 702 FRYKLPVI 725 RY V+ Sbjct: 450 GRYARRVV 457 >UniRef50_Q2U387 Cluster: Thiamine pyrophosphate-requiring enzyme; n=2; Aspergillus|Rep: Thiamine pyrophosphate-requiring enzyme - Aspergillus oryzae Length = 581 Score = 34.7 bits (76), Expect = 2.4 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 G+++ A + + P RV+ + GD AF + EI TM R KL P+I Sbjct: 423 GWSVPATLGAQVAHPHGRVVLMVGDGAFQMTAQEISTMVRMKLNPII 469 >UniRef50_Q8TPF5 Cluster: Acetolactate synthase; n=12; cellular organisms|Rep: Acetolactate synthase - Methanosarcina acetivorans Length = 583 Score = 34.7 bits (76), Expect = 2.4 Identities = 14/45 (31%), Positives = 26/45 (57%) Frame = +3 Query: 591 FAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 FA+ A+ + P ++V+ V GD +F + E+ET R ++P + Sbjct: 447 FAVPGAIGAKLAYPDRKVLAVTGDGSFLMNSQELETAIRERIPFV 491 >UniRef50_Q6L042 Cluster: Acetolactate synthase; n=6; Archaea|Rep: Acetolactate synthase - Picrophilus torridus Length = 573 Score = 34.7 bits (76), Expect = 2.4 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Frame = +3 Query: 564 FGTMGVGP-GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 F + G+G GF + AA+ + P K V+ +GD +F +G + Y +PVI Sbjct: 409 FSSTGMGTMGFGLPAAIGAKVGRPDKIVVDFDGDGSFLMTGNNLAVAVDYNIPVI 463 >UniRef50_P06169 Cluster: Pyruvate decarboxylase isozyme 1; n=3; Dikarya|Rep: Pyruvate decarboxylase isozyme 1 - Saccharomyces cerevisiae (Baker's yeast) Length = 563 Score = 34.7 bits (76), Expect = 2.4 Identities = 18/51 (35%), Positives = 26/51 (50%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 +G++G G + AA + P KRVI GD + + EI TM R+ L Sbjct: 412 WGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGL 462 >UniRef50_P0AEP8 Cluster: Glyoxylate carboligase; n=131; Bacteria|Rep: Glyoxylate carboligase - Escherichia coli O157:H7 Length = 593 Score = 34.7 bits (76), Expect = 2.4 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Frame = +3 Query: 9 ENTKLPFLPTPMGKGVVADESEYCVSTARTQA--------LLKADVILLLGARMNWMLHF 164 E T +P +PT MG G + D+ E Q LL +D++ +G R H Sbjct: 228 ELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFA-NRHT 286 Query: 165 GQPPRYAPDVKIIQVEISPEE 227 G +Y KI+ ++I P + Sbjct: 287 GSVEKYTEGRKIVHIDIEPTQ 307 >UniRef50_Q89D42 Cluster: MdlC protein; n=3; Bradyrhizobium|Rep: MdlC protein - Bradyrhizobium japonicum Length = 553 Score = 34.3 bits (75), Expect = 3.1 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = +3 Query: 522 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETM 701 + N HP HR G G G G+ + A++ P + V+C GD + +S + T Sbjct: 406 ITNLHP-HRDRFGYHGLASGGIGWGLPASVGVSIANPDRPVVCFSGDGSAMYSIQSLWTA 464 Query: 702 FRYKLPV 722 +KLP+ Sbjct: 465 AHHKLPL 471 >UniRef50_Q2W979 Cluster: Thiamine pyrophosphate-requiring enzyme; n=1; Magnetospirillum magneticum AMB-1|Rep: Thiamine pyrophosphate-requiring enzyme - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 613 Score = 34.3 bits (75), Expect = 3.1 Identities = 15/45 (33%), Positives = 23/45 (51%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 GF+ A AM AP +V+C+ GD + E++T Y + V Sbjct: 434 GFSFAGAMGAWFAAPNNQVVCIIGDGGMNMNIQELQTFVNYGVKV 478 >UniRef50_Q9X5G0 Cluster: Acetolactate synthase; n=57; Bacteria|Rep: Acetolactate synthase - Zymomonas mobilis Length = 611 Score = 34.3 bits (75), Expect = 3.1 Identities = 20/62 (32%), Positives = 32/62 (51%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P H L +G GTMG G I A + P + + G+++F + E+ T+ +Y+L Sbjct: 429 PNHFLTSGGLGTMGYGFPSIIGAQVG----NPDSLCMTIAGEASFQMNIQEMATVAQYRL 484 Query: 717 PV 722 PV Sbjct: 485 PV 486 >UniRef50_A7QYX6 Cluster: Chromosome chr16 scaffold_258, whole genome shotgun sequence; n=6; Vitis vinifera|Rep: Chromosome chr16 scaffold_258, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 866 Score = 34.3 bits (75), Expect = 3.1 Identities = 21/65 (32%), Positives = 33/65 (50%) Frame = +3 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFR 707 + +PRH L + G MG G A+ AA+ P V+ ++GD +F + E+ T+ Sbjct: 699 HKNPRHWLSSSGLGAMGFGLPAAMGAAL----AKPDAIVVDIDGDGSFMMNIQELATIRV 754 Query: 708 YKLPV 722 LPV Sbjct: 755 ENLPV 759 >UniRef50_Q28XE8 Cluster: GA18626-PA; n=2; Endopterygota|Rep: GA18626-PA - Drosophila pseudoobscura (Fruit fly) Length = 1206 Score = 34.3 bits (75), Expect = 3.1 Identities = 19/66 (28%), Positives = 30/66 (45%) Frame = +3 Query: 414 STTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLLNNHPRHRLDAGTFGTMGVGPGF 593 +TT ++ + S + H H S H +G G L+ HP R+ G G +GVG G Sbjct: 6 ATTSVITSNELSLSAHGHA--HAHTHSHTHSHGHGHSLHQHPHSRIGVGV-GGVGVGIGV 62 Query: 594 AIAAAM 611 + + Sbjct: 63 GVGVGV 68 >UniRef50_Q7D5H1 Cluster: Acetolactate synthase, large subunit, putative; n=9; Mycobacterium tuberculosis complex|Rep: Acetolactate synthase, large subunit, putative - Mycobacterium tuberculosis Length = 542 Score = 33.9 bits (74), Expect = 4.1 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = +3 Query: 564 FGTMGVGP-GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 F T+ P G IA A+ P + VIC+ GD AF G EI T + + V Sbjct: 402 FATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRV 455 >UniRef50_Q4EB17 Cluster: Putative uncharacterized protein; n=1; Wolbachia endosymbiont of Drosophila ananassae|Rep: Putative uncharacterized protein - Wolbachia endosymbiont of Drosophila ananassae Length = 561 Score = 33.9 bits (74), Expect = 4.1 Identities = 20/63 (31%), Positives = 33/63 (52%) Frame = +3 Query: 408 HCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYGRGLLLNNHPRHRLDAGTFGTMGVGP 587 H +T E+ R+S+ + R S+YHG+ G+L+ H R+R A + + VG Sbjct: 13 HDTTEEVFQHIIGVYDRYSQALDFYGRESDYHGFVSGVLM--HFRYRNVANIYLELFVGG 70 Query: 588 GFA 596 G+A Sbjct: 71 GYA 73 >UniRef50_A5TVK4 Cluster: Possible thiamine pyrophosphate enzyme; n=1; Fusobacterium nucleatum subsp. polymorphum ATCC 10953|Rep: Possible thiamine pyrophosphate enzyme - Fusobacterium nucleatum subsp. polymorphum ATCC 10953 Length = 504 Score = 33.9 bits (74), Expect = 4.1 Identities = 22/68 (32%), Positives = 33/68 (48%) Frame = +3 Query: 522 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETM 701 L+ N + G FG +G I A++ + V+C GD F FSGM I + Sbjct: 364 LILNESEELMMVGGFGPLGSSISIGIGASLANSNIH--YIVLC--GDGGFLFSGMTILNI 419 Query: 702 FRYKLPVI 725 +YKLP++ Sbjct: 420 VKYKLPIL 427 >UniRef50_Q58077 Cluster: Uncharacterized protein MJ0663; n=6; Methanococcales|Rep: Uncharacterized protein MJ0663 - Methanococcus jannaschii Length = 494 Score = 33.9 bits (74), Expect = 4.1 Identities = 16/63 (25%), Positives = 31/63 (49%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 PR+ + + +FGTMG G +I D+ + V+ + GD F + E++ + L Sbjct: 362 PRNIISSHSFGTMGFGLPASIGVKFGTIDFNIDREVVLISGDGGFLMNVEELQVVAENNL 421 Query: 717 PVI 725 ++ Sbjct: 422 KIL 424 >UniRef50_UPI00006CDE0D Cluster: hypothetical protein TTHERM_00297160; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00297160 - Tetrahymena thermophila SB210 Length = 2311 Score = 33.5 bits (73), Expect = 5.4 Identities = 23/81 (28%), Positives = 35/81 (43%) Frame = +2 Query: 299 RLSERKFSLQPQNNSWWQGLKQNKKQTPNL*RLKQAALQYH*TTTLFSKQFNKAFQKIQS 478 R E+K Q N+WW+ N KQ + Q L YH + K N+ +QK + Sbjct: 2018 RNDEKKRKSQVDPNNWWKSRYSNDKQLEKILSQTQTILDYH----IICKLQNE-YQKSYN 2072 Query: 479 LSAKERIPWIWPRFIAQQSSE 541 S ++ + WI + Q E Sbjct: 2073 PSQRKPMMWILSENLLQAPLE 2093 >UniRef50_UPI00005F9B31 Cluster: COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; n=1; Yersinia frederiksenii ATCC 33641|Rep: COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit - Yersinia frederiksenii ATCC 33641 Length = 499 Score = 33.5 bits (73), Expect = 5.4 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Frame = +2 Query: 365 NKKQTPNL*RLKQAALQYH*TTTL-FSKQFNKAFQKIQSLSAKERIPWIWPRFIAQQSSE 541 N+ Q N+ +H TTL + K FQ+ SL + WP F+ + SE Sbjct: 186 NRSQNVNVTLGASFEYVHHEVTTLEVLLNWLKGFQEFISLMINATYAFKWPEFLWAEGSE 245 Query: 542 T-QARCWYIW 568 T A+C++ W Sbjct: 246 TLHAKCYFSW 255 >UniRef50_Q7NIX5 Cluster: Indole-3-pyruvate decarboxylase; n=3; Bacteria|Rep: Indole-3-pyruvate decarboxylase - Gloeobacter violaceus Length = 550 Score = 33.5 bits (73), Expect = 5.4 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 GFA+ AA+ + R + + GD AF SG+E+ T+ R+ L P++ Sbjct: 410 GFAVPAALGAQMADARLRPLVLVGDGAFQMSGLELSTIARFGLDPIV 456 >UniRef50_Q4K6F7 Cluster: Acetolactate synthase II, large subunit; n=3; Gammaproteobacteria|Rep: Acetolactate synthase II, large subunit - Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) Length = 568 Score = 33.5 bits (73), Expect = 5.4 Identities = 15/49 (30%), Positives = 29/49 (59%) Frame = +3 Query: 90 ARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHN 236 A A+ D++L+LG+RM+ QP +A + +IIQ+++ + +N Sbjct: 268 AANHAVQNCDLLLVLGSRMDVRQTGAQPEDFARNAEIIQIDLQEGQLNN 316 >UniRef50_Q3IXG3 Cluster: Thiamine pyrophosphate-requiring enzyme; n=4; Proteobacteria|Rep: Thiamine pyrophosphate-requiring enzyme - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 550 Score = 33.5 bits (73), Expect = 5.4 Identities = 20/54 (37%), Positives = 27/54 (50%) Frame = +3 Query: 546 RLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFR 707 RL G G +G G A+AA++ C P R+ GD + GF E+ET R Sbjct: 399 RLINGPAGGIGGALGHAVAASLAC----PEARIAVASGDGSIGFHLAELETAVR 448 >UniRef50_Q1ILZ1 Cluster: Acetolactate synthase; n=5; cellular organisms|Rep: Acetolactate synthase - Acidobacteria bacterium (strain Ellin345) Length = 571 Score = 33.5 bits (73), Expect = 5.4 Identities = 19/65 (29%), Positives = 34/65 (52%) Frame = +3 Query: 528 NNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFR 707 +++PR + +G GTMG FA+ AA+ + P V + GD F + E+ T+ + Sbjct: 403 HDNPRSLITSGGLGTMG----FALPAAIGAKMANPDAEVWVIVGDGGFQMTMCELATIVQ 458 Query: 708 YKLPV 722 +L + Sbjct: 459 ERLDI 463 >UniRef50_Q759M2 Cluster: ADR254Wp; n=1; Eremothecium gossypii|Rep: ADR254Wp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 581 Score = 33.5 bits (73), Expect = 5.4 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 +G++G G + + R AP +RV+ GD A + E+ TM R +L P+I Sbjct: 420 WGSVGYSVGACLGVLVATRAAAPPRRVVLFVGDGALQLTVQELSTMVRLRLAPLI 474 >UniRef50_Q2HA42 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 797 Score = 33.5 bits (73), Expect = 5.4 Identities = 15/32 (46%), Positives = 20/32 (62%) Frame = -1 Query: 145 ILAPRSSMTSAFSRACVRAVDTQYSDSSATTP 50 IL P+S T+ SRA +R VD Q+ +S TP Sbjct: 339 ILTPKSPRTAGLSRAAMRTVDAQHLTASLPTP 370 >UniRef50_Q0CB10 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 653 Score = 33.5 bits (73), Expect = 5.4 Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 G+++ A + P KR+I + GD +F +G E+ TM R + P+I Sbjct: 485 GWSLPATLGYHVGRPDKRIILMIGDGSFQMTGQELSTMIRLRANPII 531 >UniRef50_P51852 Cluster: Indole-3-pyruvate decarboxylase; n=16; Proteobacteria|Rep: Indole-3-pyruvate decarboxylase - Azospirillum brasilense Length = 545 Score = 33.5 bits (73), Expect = 5.4 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Frame = +3 Query: 549 LDAGTFGT-MGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEI 692 +DAG G GF + A + + + GKR++ V GD AF +G E+ Sbjct: 391 IDAGLMAPGYYAGMGFGVPAGIGAQCVSGGKRILTVVGDGAFQMTGWEL 439 >UniRef50_Q8G7H0 Cluster: Acetolactate synthase; n=2; Bifidobacterium longum|Rep: Acetolactate synthase - Bifidobacterium longum Length = 655 Score = 33.1 bits (72), Expect = 7.2 Identities = 15/54 (27%), Positives = 33/54 (61%) Frame = +3 Query: 90 ARTQALLKADVILLLGARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSE 251 A T A+ +AD+++ +GAR + + G+ +AP ++I ++I P E +++ + Sbjct: 290 AATGAVQRADLLVAIGARFDDRV-TGKLDAFAPTARVIHIDIDPAEIGKNRQPD 342 Score = 33.1 bits (72), Expect = 7.2 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Frame = +3 Query: 549 LDAGTFGTMGVGPGFAIAAAMW-CRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 + +G GTMG G AI A++ R++ K V ++GD +F + E+ F PV Sbjct: 441 ISSGGLGTMGYGLPAAIGASVGSAREFEGKKPVWLIDGDGSFQMTSEELAAAFLDHAPV 499 >UniRef50_Q5LKG3 Cluster: Acetolactate synthase, large subunit, putative; n=11; Proteobacteria|Rep: Acetolactate synthase, large subunit, putative - Silicibacter pomeroyi Length = 563 Score = 33.1 bits (72), Expect = 7.2 Identities = 13/45 (28%), Positives = 27/45 (60%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 G++++AA+ P + + + GD + GF+ E+ET+ R + P+ Sbjct: 429 GYSLSAALGAWYGRPASKTVALMGDGSLGFTVGELETVCRSRAPI 473 >UniRef50_Q3M5M2 Cluster: Thiamine pyrophosphate enzyme; n=1; Anabaena variabilis ATCC 29413|Rep: Thiamine pyrophosphate enzyme - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 541 Score = 33.1 bits (72), Expect = 7.2 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 GF + + + P +R I + GD AF +GME+ T R +L P++ Sbjct: 404 GFGVPGVIGAQLADPSRRAIALVGDGAFHMTGMELLTAQRLRLNPIV 450 >UniRef50_Q0SHU3 Cluster: Pyruvate dehydrogenase; n=15; Bacteria|Rep: Pyruvate dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 591 Score = 33.1 bits (72), Expect = 7.2 Identities = 23/67 (34%), Positives = 32/67 (47%) Frame = +3 Query: 522 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETM 701 L N R L + G+M AI A + C APG++V+ V GD E+ T+ Sbjct: 399 LTPNGSRRFLSSALHGSMANALPHAIGAQV-C---APGRQVVSVSGDGGLSMLLGELVTV 454 Query: 702 FRYKLPV 722 Y+LPV Sbjct: 455 AMYRLPV 461 >UniRef50_Q186C0 Cluster: Acetolactate synthase; n=2; Clostridium difficile|Rep: Acetolactate synthase - Clostridium difficile (strain 630) Length = 564 Score = 33.1 bits (72), Expect = 7.2 Identities = 19/53 (35%), Positives = 28/53 (52%) Frame = +3 Query: 567 GTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 GTMG G G AI + D K V+ V GD +F + E+ T+ Y +P++ Sbjct: 420 GTMGFGLGAAIGTKVGNVD----KNVVLVTGDGSFRMNCNELATVANYNVPML 468 >UniRef50_Q036H9 Cluster: Pyruvate oxidase; n=1; Lactobacillus casei ATCC 334|Rep: Pyruvate oxidase - Lactobacillus casei (strain ATCC 334) Length = 586 Score = 33.1 bits (72), Expect = 7.2 Identities = 19/57 (33%), Positives = 29/57 (50%) Frame = +3 Query: 555 AGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 +G F TMG G A+A + P ++V + GD A +++T RY LP+I Sbjct: 408 SGLFATMGAGLPAALAGQL----SFPKRQVFNLTGDGAAAMVMQDLDTEVRYHLPII 460 >UniRef50_A6CD43 Cluster: Pyruvate decarboxylase; n=1; Planctomyces maris DSM 8797|Rep: Pyruvate decarboxylase - Planctomyces maris DSM 8797 Length = 563 Score = 33.1 bits (72), Expect = 7.2 Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL-PVI 725 G+++ A + AP +R I + GD +F + E+ T+ RY L P+I Sbjct: 418 GWSVGATLGYSVGAPDRRPIALIGDGSFQLTAQEVSTIIRYGLKPII 464 >UniRef50_A0PNI1 Cluster: Acetolactate synthase (Large subunit) IlvB1_2; n=1; Mycobacterium ulcerans Agy99|Rep: Acetolactate synthase (Large subunit) IlvB1_2 - Mycobacterium ulcerans (strain Agy99) Length = 558 Score = 33.1 bits (72), Expect = 7.2 Identities = 20/63 (31%), Positives = 30/63 (47%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P L G+MG+ AIAA + P ++V+ V GD F + ++ET R L Sbjct: 401 PNTMLIDHALGSMGISLPAAIAAKL----VHPDRKVVVVTGDGGFAMNSQDLETAVRLGL 456 Query: 717 PVI 725 +I Sbjct: 457 DLI 459 >UniRef50_Q9SLK4 Cluster: F20D21.12 protein; n=3; Arabidopsis thaliana|Rep: F20D21.12 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 444 Score = 33.1 bits (72), Expect = 7.2 Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = +3 Query: 474 NHCQRRSEYHGYGRGLLLNNHPRHRLDAGTFGTMGVGPG-FAIAAAMWCRD-YAPGKRVI 647 N+ R S H + G +NN P+H G G +GVG G F++A W R+ Y+P V Sbjct: 218 NNSSRNS--HSHTVGFNVNNGPQHHFSQG-IGGVGVGEGNFSMANGGWQRNSYSP---VN 271 Query: 648 CVEGDSAFGFSGME 689 + ++A F GM+ Sbjct: 272 SLNYNTANEFFGMQ 285 >UniRef50_Q7QY44 Cluster: GLP_10_3431_5173; n=1; Giardia lamblia ATCC 50803|Rep: GLP_10_3431_5173 - Giardia lamblia ATCC 50803 Length = 580 Score = 33.1 bits (72), Expect = 7.2 Identities = 20/89 (22%), Positives = 40/89 (44%) Frame = +1 Query: 280 YRSSCKKVVRKEVLIATSKQQLVAGTETEQKANTEFVEAQASSTAVPLNYYTVFKTVQQG 459 YR S ++ +K + ++T QQ A + ++ + NY +F+ + Sbjct: 311 YRDSIEEKDQKILELSTLVQQKTAEADVVKEQLLSAEDLLRDQKEAAANYKNLFRDRSRA 370 Query: 460 IPKDSIIVSEGANTMDMAEVYCSTIIRDT 546 + K + +++ N +D+A S I RDT Sbjct: 371 LEKTTFLLNSKTNELDVAMSLASEIQRDT 399 >UniRef50_Q4N2S4 Cluster: Zinc finger protein, putative; n=2; Theileria|Rep: Zinc finger protein, putative - Theileria parva Length = 532 Score = 33.1 bits (72), Expect = 7.2 Identities = 17/56 (30%), Positives = 29/56 (51%) Frame = +1 Query: 382 EFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDMAEVYCSTIIRDTG 549 + VEAQ S ++P+ Y + F T + + DS+ V G+N + V S+ + G Sbjct: 171 DVVEAQRSRVSMPVEYDSYFLTNSENLRLDSLTVFAGSNETENGSVELSSEAQSKG 226 >UniRef50_A0E9R8 Cluster: Chromosome undetermined scaffold_85, whole genome shotgun sequence; n=6; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_85, whole genome shotgun sequence - Paramecium tetraurelia Length = 418 Score = 33.1 bits (72), Expect = 7.2 Identities = 18/46 (39%), Positives = 24/46 (52%) Frame = +2 Query: 245 IRITVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLKQNKKQTP 382 I T D+R F E LVKRLS +++ Q N W LK++ P Sbjct: 364 IPYTASRDLRDFIENLVKRLSRERYTAQQTYNHGW--LKRSMSVVP 407 >UniRef50_A7TRE3 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 636 Score = 33.1 bits (72), Expect = 7.2 Identities = 17/46 (36%), Positives = 26/46 (56%) Frame = +3 Query: 585 PGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 P F + R+Y P R+I +EGD A + E+ TM R+K+P+ Sbjct: 482 PKFHLNDHSLARNYTP--RLILLEGDGAAQMTVQELTTMLRHKIPM 525 >UniRef50_Q9Q8F9 Cluster: M144R; n=3; Leporipoxvirus|Rep: M144R - Myxoma virus Length = 300 Score = 32.7 bits (71), Expect = 9.5 Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 6/57 (10%) Frame = -1 Query: 385 IRCLLFVLFQSLPPT---VVLR---LQ*ELPFGQPFYKSFCKRSNV*VYCNSDFLLL 233 +RC+ + PPT +V R LQ G PF K FC ++ V CN DF L+ Sbjct: 129 VRCINETTWYPSPPTCKMIVCRFPALQNGYVHGVPFIKRFCYKNRVRFTCNPDFTLV 185 >UniRef50_Q88S56 Cluster: Pyruvate oxidase; n=2; Lactobacillus plantarum|Rep: Pyruvate oxidase - Lactobacillus plantarum Length = 584 Score = 32.7 bits (71), Expect = 9.5 Identities = 24/71 (33%), Positives = 35/71 (49%) Frame = +3 Query: 513 RGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEI 692 R L LN + A +GTMG G +AA + +Y P K+V + GD + ++ Sbjct: 394 RQLPLNKQQTFTMSAW-YGTMGFGLPAGLAAQL---NY-PKKQVWSISGDGGYAMVMPDL 448 Query: 693 ETMFRYKLPVI 725 T +Y LPVI Sbjct: 449 LTEVKYHLPVI 459 >UniRef50_Q5FHQ7 Cluster: Pyruvate oxidase; n=12; Lactobacillaceae|Rep: Pyruvate oxidase - Lactobacillus acidophilus Length = 601 Score = 32.7 bits (71), Expect = 9.5 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +3 Query: 522 LLNNHPRHR-LDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIET 698 LLN H + +G TMG G A+ AA P + V + GD F E+ T Sbjct: 394 LLNLHDDQKWTTSGLHATMGYGAPAALMAAT----VYPDREVWNLAGDGGFAMMNQELLT 449 Query: 699 MFRYKLPVI 725 M RY + V+ Sbjct: 450 MSRYNMHVL 458 >UniRef50_P96591 Cluster: YdaP protein; n=11; Bacillaceae|Rep: YdaP protein - Bacillus subtilis Length = 574 Score = 32.7 bits (71), Expect = 9.5 Identities = 19/51 (37%), Positives = 27/51 (52%) Frame = +3 Query: 570 TMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 TMG G AIAA++ P ++ I V GD F ++ T +YKLP+ Sbjct: 409 TMGCGLPGAIAASL----SEPERQAIAVCGDGGFSMVMQDLPTAVKYKLPI 455 >UniRef50_Q26HU8 Cluster: Putative uncharacterized protein; n=1; Flavobacteria bacterium BBFL7|Rep: Putative uncharacterized protein - Flavobacteria bacterium BBFL7 Length = 399 Score = 32.7 bits (71), Expect = 9.5 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Frame = +1 Query: 205 RSKY-LLKNFTTARNQNYSTLRH*TF-YRSSCKKVVRKEVLIATSKQQLVAGTETEQKAN 378 RS+Y +L +T N+ + YR + + +R + + T+ + + + + Sbjct: 47 RSQYPILDKYTYLNTANHGLISQELIDYRINVMEQMRDQASLYTNTRNVFI--DEVRSTI 104 Query: 379 TEFVEAQASSTAVPLNYYTVFKTVQQGIPKDS 474 +FV+A +TAV N+ T F T+ +GI K S Sbjct: 105 AQFVDATIENTAVIPNFSTGFNTLIEGIDKQS 136 >UniRef50_Q1N3D1 Cluster: Pyruvate oxidase; n=2; Gammaproteobacteria|Rep: Pyruvate oxidase - Oceanobacter sp. RED65 Length = 555 Score = 32.7 bits (71), Expect = 9.5 Identities = 19/57 (33%), Positives = 28/57 (49%) Frame = +3 Query: 555 AGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 + GTMGVG AI A + P + VI + GD F + ++ T Y LP++ Sbjct: 400 SSALGTMGVGLPGAIGAKL----AYPDRTVISLVGDGGFAMTMTDLVTAVNYDLPMV 452 >UniRef50_Q1ARE6 Cluster: Acetolactate synthase; n=4; Bacteria|Rep: Acetolactate synthase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 564 Score = 32.7 bits (71), Expect = 9.5 Identities = 12/43 (27%), Positives = 28/43 (65%) Frame = +3 Query: 99 QALLKADVILLLGARMNWMLHFGQPPRYAPDVKIIQVEISPEE 227 +A+ ++D++ +G R + + G P R+AP+ +++ ++I P E Sbjct: 270 RAIDRSDLLFAVGMRFDDRIT-GDPSRFAPNARVVHIDIDPSE 311 >UniRef50_A6QC71 Cluster: Acetolactate synthase, large subunit; n=1; Sulfurovum sp. NBC37-1|Rep: Acetolactate synthase, large subunit - Sulfurovum sp. (strain NBC37-1) Length = 597 Score = 32.7 bits (71), Expect = 9.5 Identities = 15/45 (33%), Positives = 24/45 (53%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPV 722 G+ + AA+ K VICV GD + + E++T+ Y LP+ Sbjct: 426 GYDLPAAIGACIANGKKEVICVSGDGSLQMNLQELQTIIHYNLPI 470 >UniRef50_A6CP74 Cluster: Acetolactate synthase large subunit; n=1; Bacillus sp. SG-1|Rep: Acetolactate synthase large subunit - Bacillus sp. SG-1 Length = 549 Score = 32.7 bits (71), Expect = 9.5 Identities = 19/54 (35%), Positives = 27/54 (50%) Frame = +3 Query: 564 FGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 FG MG GF+I A + +P K V+C+ GD G E T ++PV+ Sbjct: 410 FGAMGHAIGFSIGAKI----ASPEKPVVCLTGDGCTLMHGTEFITAKNNRVPVL 459 >UniRef50_A0VEM6 Cluster: Thiamine pyrophosphate enzyme-like TPP-binding; n=2; Proteobacteria|Rep: Thiamine pyrophosphate enzyme-like TPP-binding - Delftia acidovorans SPH-1 Length = 575 Score = 32.7 bits (71), Expect = 9.5 Identities = 18/48 (37%), Positives = 24/48 (50%) Frame = +3 Query: 582 GPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G G+ + AM R G +V C+ GD FG E+ET R + VI Sbjct: 438 GLGWGMPMAMGARLAQDGGQVFCLVGDGGFGHVWSEMETCRRMGIKVI 485 >UniRef50_A0IIS8 Cluster: Thiamine pyrophosphate enzyme-like TPP-binding; n=2; Proteobacteria|Rep: Thiamine pyrophosphate enzyme-like TPP-binding - Serratia proteamaculans 568 Length = 609 Score = 32.7 bits (71), Expect = 9.5 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +3 Query: 588 GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 G+AI A + + AP + + V GD GMEI+T RY++ Sbjct: 466 GWAICAGIGIKLAAPHRDCVVVTGDGCMLMHGMEIQTAARYQV 508 >UniRef50_A2ESQ8 Cluster: Surface antigen BspA-like; n=3; Trichomonas vaginalis G3|Rep: Surface antigen BspA-like - Trichomonas vaginalis G3 Length = 744 Score = 32.7 bits (71), Expect = 9.5 Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%) Frame = +3 Query: 396 SSKQHCSTTELLHCFQNSSTR-HSKRFNHCQRRSE 497 SS HCS E + F NSSTR +S+ F+HC++ S+ Sbjct: 194 SSFSHCSQLEKVR-FLNSSTRLNSQAFSHCEKLSD 227 >UniRef50_Q8ZTD9 Cluster: Acetolactate synthase; n=5; Thermoproteaceae|Rep: Acetolactate synthase - Pyrobaculum aerophilum Length = 556 Score = 32.7 bits (71), Expect = 9.5 Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Frame = +3 Query: 552 DAGTFGTM-GVGP-GFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 + G+F T G+G GF + AA+ + + V+C++GD +F + + + Y LP++ Sbjct: 388 EPGSFITSAGLGTMGFCVPAALGAKLADRSRPVLCIDGDGSFQMTMNNLALVRDYNLPIV 447 >UniRef50_Q8PT77 Cluster: Acetolactate synthase; n=4; cellular organisms|Rep: Acetolactate synthase - Methanosarcina mazei (Methanosarcina frisia) Length = 584 Score = 32.7 bits (71), Expect = 9.5 Identities = 18/62 (29%), Positives = 32/62 (51%) Frame = +3 Query: 537 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKL 716 P+ + +G+FGTMG F++ A+ P VI ++GD + + E+ T+ L Sbjct: 422 PKSFMTSGSFGTMG----FSLPTAIGVHYANPHSGVIAIDGDGSLRMNLGELHTIASLDL 477 Query: 717 PV 722 P+ Sbjct: 478 PI 479 >UniRef50_P20906 Cluster: Benzoylformate decarboxylase; n=14; Bacteria|Rep: Benzoylformate decarboxylase - Pseudomonas putida Length = 528 Score = 32.7 bits (71), Expect = 9.5 Identities = 17/48 (35%), Positives = 27/48 (56%) Frame = +3 Query: 582 GPGFAIAAAMWCRDYAPGKRVICVEGDSAFGFSGMEIETMFRYKLPVI 725 G GFA+ AA+ + P ++VI V GD + +S + T +Y +P I Sbjct: 402 GLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTI 449 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 734,514,161 Number of Sequences: 1657284 Number of extensions: 14838130 Number of successful extensions: 42417 Number of sequences better than 10.0: 182 Number of HSP's better than 10.0 without gapping: 40667 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 42345 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 59090914597 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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