Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= mg--0018
(491 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 77 4e-14
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 77 4e-14
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 77 4e-14
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 73 5e-13
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 73 5e-13
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 73 5e-13
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 73 5e-13
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 73 5e-13
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 73 5e-13
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 70 5e-12
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 62 1e-09
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 62 1e-09
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 62 1e-09
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 60 5e-09
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 55 1e-07
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 55 1e-07
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 55 1e-07
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 55 1e-07
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 55 1e-07
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 43 7e-04
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 43 7e-04
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 43 7e-04
X75962-1|CAA53576.1| 277|Homo sapiens OX40 homologue protein. 33 0.71
S76792-1|AAB33944.1| 274|Homo sapiens OX40 protein. 33 0.71
DQ118974-1|AAZ15374.1| 277|Homo sapiens tumor necrosis factor r... 33 0.71
BC105072-1|AAI05073.1| 277|Homo sapiens tumor necrosis factor r... 33 0.71
BC105070-1|AAI05071.1| 277|Homo sapiens tumor necrosis factor r... 33 0.71
AL162741-8|CAI23250.1| 277|Homo sapiens tumor necrosis factor r... 33 0.71
AL162741-7|CAI23249.1| 131|Homo sapiens tumor necrosis factor r... 33 0.71
AJ277151-1|CAB96543.1| 277|Homo sapiens CD134 antigen protein. 33 0.71
AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation ... 30 3.8
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 76.6 bits (180), Expect = 4e-14
Identities = 35/83 (42%), Positives = 46/83 (55%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
+ P +L LK +YNDP YVTENG + E L D RI Y R + L ++
Sbjct: 1724 MTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDK 1783
Query: 185 VRLKGYMAWSLMDNYEWMAGYTE 253
V L+GY WS MDN+EW G++E
Sbjct: 1784 VDLRGYTVWSAMDNFEWATGFSE 1806
Score = 69.7 bits (163), Expect = 5e-12
Identities = 36/77 (46%), Positives = 50/77 (64%), Gaps = 3/77 (3%)
Frame = +2
Query: 29 VLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRLKG 199
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L+G
Sbjct: 1256 LLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDLRG 1312
Query: 200 YMAWSLMDNYEWMAGYT 250
Y+AWSLMDN+EW+ GYT
Sbjct: 1313 YVAWSLMDNFEWLNGYT 1329
Score = 38.3 bits (85), Expect = 0.014
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 815 FGLHHVNFSDSSKSRTPRKSAYFFTSII 842
Score = 37.5 bits (83), Expect = 0.025
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGLY VDF++ RPRT R SA Y E++
Sbjct: 1332 FGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 35.5 bits (78), Expect = 0.10
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Frame = +2
Query: 71 YVTENGWATSPEVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAG 244
Y+ NG L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +G
Sbjct: 751 YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSG 810
Query: 245 YTE 253
Y++
Sbjct: 811 YSQ 813
Score = 35.1 bits (77), Expect = 0.13
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILR 342
FGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1808 FGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 76.6 bits (180), Expect = 4e-14
Identities = 35/83 (42%), Positives = 46/83 (55%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
+ P +L LK +YNDP YVTENG + E L D RI Y R + L ++
Sbjct: 1724 MTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDK 1783
Query: 185 VRLKGYMAWSLMDNYEWMAGYTE 253
V L+GY WS MDN+EW G++E
Sbjct: 1784 VDLRGYTVWSAMDNFEWATGFSE 1806
Score = 69.7 bits (163), Expect = 5e-12
Identities = 36/77 (46%), Positives = 50/77 (64%), Gaps = 3/77 (3%)
Frame = +2
Query: 29 VLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRLKG 199
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L+G
Sbjct: 1256 LLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDLRG 1312
Query: 200 YMAWSLMDNYEWMAGYT 250
Y+AWSLMDN+EW+ GYT
Sbjct: 1313 YVAWSLMDNFEWLNGYT 1329
Score = 38.3 bits (85), Expect = 0.014
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 815 FGLHHVNFSDSSKSRTPRKSAYFFTSII 842
Score = 37.5 bits (83), Expect = 0.025
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGLY VDF++ RPRT R SA Y E++
Sbjct: 1332 FGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 35.5 bits (78), Expect = 0.10
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Frame = +2
Query: 71 YVTENGWATSPEVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAG 244
Y+ NG L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +G
Sbjct: 751 YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSG 810
Query: 245 YTE 253
Y++
Sbjct: 811 YSQ 813
Score = 35.1 bits (77), Expect = 0.13
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILR 342
FGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1808 FGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 76.6 bits (180), Expect = 4e-14
Identities = 35/83 (42%), Positives = 46/83 (55%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
+ P +L LK +YNDP YVTENG + E L D RI Y R + L ++
Sbjct: 1724 MTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDK 1783
Query: 185 VRLKGYMAWSLMDNYEWMAGYTE 253
V L+GY WS MDN+EW G++E
Sbjct: 1784 VDLRGYTVWSAMDNFEWATGFSE 1806
Score = 69.7 bits (163), Expect = 5e-12
Identities = 36/77 (46%), Positives = 50/77 (64%), Gaps = 3/77 (3%)
Frame = +2
Query: 29 VLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRLKG 199
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L+G
Sbjct: 1256 LLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDLRG 1312
Query: 200 YMAWSLMDNYEWMAGYT 250
Y+AWSLMDN+EW+ GYT
Sbjct: 1313 YVAWSLMDNFEWLNGYT 1329
Score = 38.3 bits (85), Expect = 0.014
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 815 FGLHHVNFSDSSKSRTPRKSAYFFTSII 842
Score = 37.5 bits (83), Expect = 0.025
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGLY VDF++ RPRT R SA Y E++
Sbjct: 1332 FGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 35.5 bits (78), Expect = 0.10
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Frame = +2
Query: 71 YVTENGWATSPEVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAG 244
Y+ NG L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +G
Sbjct: 751 YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSG 810
Query: 245 YTE 253
Y++
Sbjct: 811 YSQ 813
Score = 35.1 bits (77), Expect = 0.13
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILR 342
FGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1808 FGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 72.9 bits (171), Expect = 5e-13
Identities = 30/83 (36%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
++P + +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++
Sbjct: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLD 407
Query: 185 -VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 408 KVNLQVYCAWSLLDNFEWNQGYS 430
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 433 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 72.9 bits (171), Expect = 5e-13
Identities = 30/83 (36%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
++P + +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++
Sbjct: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLD 407
Query: 185 -VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 408 KVNLQVYCAWSLLDNFEWNQGYS 430
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 433 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 72.9 bits (171), Expect = 5e-13
Identities = 30/83 (36%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
++P + +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++
Sbjct: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLD 407
Query: 185 -VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 408 KVNLQVYCAWSLLDNFEWNQGYS 430
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 433 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 72.9 bits (171), Expect = 5e-13
Identities = 30/83 (36%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
++P + +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++
Sbjct: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLD 407
Query: 185 -VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 408 KVNLQVYCAWSLLDNFEWNQGYS 430
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 433 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 72.9 bits (171), Expect = 5e-13
Identities = 30/83 (36%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
++P + +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++
Sbjct: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLD 407
Query: 185 -VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 408 KVNLQVYCAWSLLDNFEWNQGYS 430
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 433 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 72.9 bits (171), Expect = 5e-13
Identities = 30/83 (36%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG 184
++P + +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++
Sbjct: 348 VVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLD 407
Query: 185 -VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 408 KVNLQVYCAWSLLDNFEWNQGYS 430
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 433 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 69.7 bits (163), Expect = 5e-12
Identities = 36/77 (46%), Positives = 50/77 (64%), Gaps = 3/77 (3%)
Frame = +2
Query: 29 VLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRLKG 199
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L+G
Sbjct: 688 LLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDLRG 744
Query: 200 YMAWSLMDNYEWMAGYT 250
Y+AWSLMDN+EW+ GYT
Sbjct: 745 YVAWSLMDNFEWLNGYT 761
Score = 38.3 bits (85), Expect = 0.014
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 247 FGLHHVNFSDSSKSRTPRKSAYFFTSII 274
Score = 37.5 bits (83), Expect = 0.025
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
FGLY VDF++ RPRT R SA Y E++
Sbjct: 764 FGLYHVDFNNTNRPRTARASARYYTEVI 791
Score = 35.5 bits (78), Expect = 0.10
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Frame = +2
Query: 71 YVTENGWATSPEVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAG 244
Y+ NG L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +G
Sbjct: 183 YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSG 242
Query: 245 YTE 253
Y++
Sbjct: 243 YSQ 245
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 62.1 bits (144), Expect = 1e-09
Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Frame = +2
Query: 17 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 193
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 194 KGYMAWSLMDNYEWMAGYT 250
GY AWSL+D +EW YT
Sbjct: 455 FGYTAWSLLDGFEWQDAYT 473
Score = 32.7 bits (71), Expect = 0.71
Identities = 13/28 (46%), Positives = 19/28 (67%)
Frame = +1
Query: 259 GLYEVDFSDPARPRTPRKSAFVYKEILR 342
GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 477 GLFYVDFNSKQKERKPKSSAHYYKQIIR 504
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 62.1 bits (144), Expect = 1e-09
Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Frame = +2
Query: 17 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 193
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 194 KGYMAWSLMDNYEWMAGYT 250
GY AWSL+D +EW YT
Sbjct: 455 FGYTAWSLLDGFEWQDAYT 473
Score = 32.7 bits (71), Expect = 0.71
Identities = 13/28 (46%), Positives = 19/28 (67%)
Frame = +1
Query: 259 GLYEVDFSDPARPRTPRKSAFVYKEILR 342
GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 477 GLFYVDFNSKQKERKPKSSAHYYKQIIR 504
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 62.1 bits (144), Expect = 1e-09
Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Frame = +2
Query: 17 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 193
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 194 KGYMAWSLMDNYEWMAGYT 250
GY AWSL+D +EW YT
Sbjct: 455 FGYTAWSLLDGFEWQDAYT 473
Score = 32.7 bits (71), Expect = 0.71
Identities = 13/28 (46%), Positives = 19/28 (67%)
Frame = +1
Query: 259 GLYEVDFSDPARPRTPRKSAFVYKEILR 342
GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 477 GLFYVDFNSKQKERKPKSSAHYYKQIIR 504
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 59.7 bits (138), Expect = 5e-09
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 29 VLTHLKNKYNDPIFYVTENGWATSPE-VGLEDDDRITYYRAALENILDSLDAGVRLKGYM 205
+L + +Y DP YV ENG + L D+ RI Y + + +L ++ G +KGY
Sbjct: 394 LLNFAQTQYGDPPIYVMENGASQKFHCTQLCDEWRIQYLKGYINEMLKAIKDGANIKGYT 453
Query: 206 AWSLMDNYEWMAGYTE 253
+WSL+D +EW GY++
Sbjct: 454 SWSLLDKFEWEKGYSD 469
Score = 31.5 bits (68), Expect = 1.6
Identities = 12/28 (42%), Positives = 19/28 (67%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEIL 339
+G Y V+F+D +PR P+ S YK+I+
Sbjct: 471 YGFYYVEFNDRNKPRYPKASVQYYKKII 498
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 PNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDA-GV 187
PN + +L+ + ++N P ++ ENGW S +D + Y + + L ++ GV
Sbjct: 119 PN-LRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGV 177
Query: 188 RLKGYMAWSLMDNYEWMAGYT 250
+ GY AWSLMD +EW GY+
Sbjct: 178 DVIGYTAWSLMDGFEWHRGYS 198
Score = 33.5 bits (73), Expect = 0.41
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--L 175
++P + VL LK KY D Y+ NG + EDD R+ Y + + L + L
Sbjct: 574 VVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHIL 631
Query: 176 DAGVRLKGYMAWSLMD 223
D G+ L GY A+S D
Sbjct: 632 D-GINLCGYFAYSFND 646
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 PNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDA-GV 187
PN + +L+ + ++N P ++ ENGW S +D + Y + + L ++ GV
Sbjct: 392 PN-LRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGV 450
Query: 188 RLKGYMAWSLMDNYEWMAGYT 250
+ GY AWSLMD +EW GY+
Sbjct: 451 DVIGYTAWSLMDGFEWHRGYS 471
Score = 33.5 bits (73), Expect = 0.41
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--L 175
++P + VL LK KY D Y+ NG + EDD R+ Y + + L + L
Sbjct: 847 VVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHIL 904
Query: 176 DAGVRLKGYMAWSLMD 223
D G+ L GY A+S D
Sbjct: 905 D-GINLCGYFAYSFND 919
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 PNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDA-GV 187
PN + +L+ + ++N P ++ ENGW S +D + Y + + L ++ GV
Sbjct: 392 PN-LRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGV 450
Query: 188 RLKGYMAWSLMDNYEWMAGYT 250
+ GY AWSLMD +EW GY+
Sbjct: 451 DVIGYTAWSLMDGFEWHRGYS 471
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 PNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDA-GV 187
PN + +L+ + ++N P ++ ENGW S +D + Y + + L ++ GV
Sbjct: 392 PN-LRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGV 450
Query: 188 RLKGYMAWSLMDNYEWMAGYT 250
+ GY AWSLMD +EW GY+
Sbjct: 451 DVIGYTAWSLMDGFEWHRGYS 471
Score = 33.5 bits (73), Expect = 0.41
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--L 175
++P + VL LK KY D Y+ NG + EDD R+ Y + + L + L
Sbjct: 847 VVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHIL 904
Query: 176 DAGVRLKGYMAWSLMD 223
D G+ L GY A+S D
Sbjct: 905 D-GINLCGYFAYSFND 919
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 55.2 bits (127), Expect = 1e-07
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 11 PNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDA-GV 187
PN + +L+ + ++N P ++ ENGW S +D + Y + + L ++ GV
Sbjct: 392 PN-LRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGV 450
Query: 188 RLKGYMAWSLMDNYEWMAGYT 250
+ GY AWSLMD +EW GY+
Sbjct: 451 DVIGYTAWSLMDGFEWHRGYS 471
Score = 33.5 bits (73), Expect = 0.41
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Frame = +2
Query: 5 LMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--L 175
++P + VL LK KY D Y+ NG + EDD R+ Y + + L + L
Sbjct: 847 VVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHIL 904
Query: 176 DAGVRLKGYMAWSLMD 223
D G+ L GY A+S D
Sbjct: 905 D-GINLCGYFAYSFND 919
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 126 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
Score = 35.9 bits (79), Expect = 0.076
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +2
Query: 185 VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYS 123
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 126 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
Score = 35.9 bits (79), Expect = 0.076
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +2
Query: 185 VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYS 123
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 42.7 bits (96), Expect = 7e-04
Identities = 18/34 (52%), Positives = 24/34 (70%)
Frame = +1
Query: 256 FGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 357
FGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 126 FGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
Score = 35.9 bits (79), Expect = 0.076
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +2
Query: 185 VRLKGYMAWSLMDNYEWMAGYT 250
V L+ Y AWSL+DN+EW GY+
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYS 123
>X75962-1|CAA53576.1| 277|Homo sapiens OX40 homologue protein.
Length = 277
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 108 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
>S76792-1|AAB33944.1| 274|Homo sapiens OX40 protein.
Length = 274
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 105 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 140
>DQ118974-1|AAZ15374.1| 277|Homo sapiens tumor necrosis factor
receptor superfamily, member 4 protein.
Length = 277
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 108 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
>BC105072-1|AAI05073.1| 277|Homo sapiens tumor necrosis factor
receptor superfamily, member 4 protein.
Length = 277
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 108 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
>BC105070-1|AAI05071.1| 277|Homo sapiens tumor necrosis factor
receptor superfamily, member 4 protein.
Length = 277
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 108 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
>AL162741-8|CAI23250.1| 277|Homo sapiens tumor necrosis factor
receptor superfamily, member 4 protein.
Length = 277
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 108 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
>AL162741-7|CAI23249.1| 131|Homo sapiens tumor necrosis factor
receptor superfamily, member 4 protein.
Length = 131
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 53 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 88
>AJ277151-1|CAB96543.1| 277|Homo sapiens CD134 antigen protein.
Length = 277
Score = 32.7 bits (71), Expect = 0.71
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Frame = -1
Query: 299 RGRAGSEKSTSYKPKVRCI-LPSIHSYPSDSRPCSP 195
R RAG++ SYKP V C P H P D++ C P
Sbjct: 108 RCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKP 143
>AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation
factor 1 variant protein.
Length = 208
Score = 30.3 bits (65), Expect = 3.8
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +3
Query: 291 PPSHPAQV-RVRLQGDLEEQGHRPR 362
PP HPA + R R G L +GHRPR
Sbjct: 71 PPPHPASISRPRPPGPLPLRGHRPR 95
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,730,765
Number of Sequences: 237096
Number of extensions: 1360258
Number of successful extensions: 6897
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 6787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6870
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4423060356
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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