Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV32529
(439 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022777-1|AAH22777.1| 422|Homo sapiens acylglycerol kinase pro... 121 1e-27
AK001704-1|BAA91848.1| 422|Homo sapiens protein ( Homo sapiens ... 121 1e-27
AJ278150-1|CAB93536.1| 422|Homo sapiens putative lipid kinase p... 121 1e-27
AK222769-1|BAD96489.1| 422|Homo sapiens multi-substrate lipid k... 120 2e-27
AC099547-1|AAS07537.1| 162|Homo sapiens unknown protein. 118 9e-27
EF107108-1|ABK81123.1| 761|Homo sapiens sphingosine kinase-2 va... 56 5e-08
BC010671-1|AAH10671.1| 618|Homo sapiens SPHK2 protein protein. 56 5e-08
BC006161-1|AAH06161.1| 654|Homo sapiens sphingosine kinase 2 pr... 56 5e-08
AK000599-1|BAA91280.1| 354|Homo sapiens protein ( Homo sapiens ... 56 5e-08
AF245447-1|AAF74124.1| 618|Homo sapiens sphingosine kinase type... 56 5e-08
BC030553-1|AAH30553.1| 470|Homo sapiens sphingosine kinase 1 pr... 54 2e-07
BC014439-1|AAH14439.1| 470|Homo sapiens sphingosine kinase 1 pr... 54 2e-07
BC009419-1|AAH09419.1| 398|Homo sapiens sphingosine kinase 1 pr... 54 2e-07
BC008040-1|AAH08040.1| 384|Homo sapiens SPHK1 protein protein. 54 2e-07
AY278525-1|AAP35060.1| 384|Homo sapiens sphingosine kinase 1 pr... 54 2e-07
AK023393-1|BAB14558.1| 384|Homo sapiens protein ( Homo sapiens ... 54 2e-07
AK022402-1|BAB14028.1| 384|Homo sapiens protein ( Homo sapiens ... 54 2e-07
AF266756-1|AAF73470.1| 384|Homo sapiens sphingosine kinase prot... 54 2e-07
AF238083-1|AAF73423.1| 384|Homo sapiens sphingosine kinase-1 pr... 54 2e-07
AF200328-1|AAG01980.1| 384|Homo sapiens sphingosine kinase prot... 54 2e-07
AY357073-1|AAR13670.1| 532|Homo sapiens ceramide kinase-like pr... 51 2e-06
AJ640141-1|CAG26695.1| 532|Homo sapiens ceramide kinase-like pr... 51 2e-06
AJ245504-1|CAB92131.1| 381|Homo sapiens sphingosine kinase prot... 51 2e-06
AJ697855-1|CAG26977.1| 378|Homo sapiens ceramide kinase-like pr... 48 2e-05
CR456404-1|CAG30290.1| 537|Homo sapiens bK29F11.1 protein. 45 1e-04
BC126940-1|AAI26941.1| 537|Homo sapiens ceramide kinase protein. 45 1e-04
AL118516-1|CAI17953.1| 537|Homo sapiens protein ( Human DNA seq... 45 1e-04
AL096766-1|CAI18819.1| 537|Homo sapiens protein ( Human DNA seq... 45 1e-04
AJ457828-1|CAD29884.1| 537|Homo sapiens putative lipid kinase p... 45 1e-04
AB079066-1|BAC01154.1| 537|Homo sapiens ceramide kinase protein. 45 1e-04
AB051433-1|BAB33316.1| 481|Homo sapiens KIAA1646 protein protein. 45 1e-04
AY690329-1|AAW47988.1| 558|Homo sapiens ceramide kinase-like pr... 31 0.021
AF219939-1|AAF43006.1| 931|Homo sapiens diacylglycerol kinase i... 31 1.7
AF061936-1|AAC62010.1| 1065|Homo sapiens diacylglycerol kinase i... 31 1.7
AB209167-1|BAD92404.1| 871|Homo sapiens diacylglycerol kinase, ... 31 1.7
AJ697857-1|CAG26979.1| 241|Homo sapiens ceramide kinase-like pr... 31 2.3
>BC022777-1|AAH22777.1| 422|Homo sapiens acylglycerol kinase
protein.
Length = 422
Score = 121 bits (291), Expect = 1e-27
Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +3
Query: 3 KSVLGAVAIYYAGATAKEKYEINILMRAACKEAAIYGEALLPIERNPTVITVILNPVANK 182
K+ G + + G K+ N+L RAAC+EA ++G L+P TV LNP A K
Sbjct: 14 KTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACK 73
Query: 183 RKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIVETLRGTEAIIVAGGDGTLSETVT 362
KA+ FEK P V +V+T EG AK+++E + T+ IIVAGGDGTL E VT
Sbjct: 74 GKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVT 133
Query: 363 GLLRRNDQA--NMFPVGVLPLGRTNSI 437
G+LRR D+A + P+G +PLG T+S+
Sbjct: 134 GVLRRTDEATFSKIPIGFIPLGETSSL 160
>AK001704-1|BAA91848.1| 422|Homo sapiens protein ( Homo sapiens
cDNA FLJ10842 fis, clone NT2RP4001343. ).
Length = 422
Score = 121 bits (291), Expect = 1e-27
Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +3
Query: 3 KSVLGAVAIYYAGATAKEKYEINILMRAACKEAAIYGEALLPIERNPTVITVILNPVANK 182
K+ G + + G K+ N+L RAAC+EA ++G L+P TV LNP A K
Sbjct: 14 KTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACK 73
Query: 183 RKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIVETLRGTEAIIVAGGDGTLSETVT 362
KA+ FEK P V +V+T EG AK+++E + T+ IIVAGGDGTL E VT
Sbjct: 74 GKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVT 133
Query: 363 GLLRRNDQA--NMFPVGVLPLGRTNSI 437
G+LRR D+A + P+G +PLG T+S+
Sbjct: 134 GVLRRTDEATFSKIPIGFIPLGETSSL 160
>AJ278150-1|CAB93536.1| 422|Homo sapiens putative lipid kinase
protein.
Length = 422
Score = 121 bits (291), Expect = 1e-27
Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +3
Query: 3 KSVLGAVAIYYAGATAKEKYEINILMRAACKEAAIYGEALLPIERNPTVITVILNPVANK 182
K+ G + + G K+ N+L RAAC+EA ++G L+P TV LNP A K
Sbjct: 14 KTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACK 73
Query: 183 RKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIVETLRGTEAIIVAGGDGTLSETVT 362
KA+ FEK P V +V+T EG AK+++E + T+ IIVAGGDGTL E VT
Sbjct: 74 GKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVT 133
Query: 363 GLLRRNDQA--NMFPVGVLPLGRTNSI 437
G+LRR D+A + P+G +PLG T+S+
Sbjct: 134 GVLRRTDEATFSKIPIGFIPLGETSSL 160
>AK222769-1|BAD96489.1| 422|Homo sapiens multi-substrate lipid
kinase variant protein.
Length = 422
Score = 120 bits (289), Expect = 2e-27
Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 2/147 (1%)
Frame = +3
Query: 3 KSVLGAVAIYYAGATAKEKYEINILMRAACKEAAIYGEALLPIERNPTVITVILNPVANK 182
K+ G + + G K+ N+L RAAC+EA ++G L+P TV LNP A K
Sbjct: 14 KTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACK 73
Query: 183 RKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIVETLRGTEAIIVAGGDGTLSETVT 362
KA+ FEK P V +V+T EG AK+++E + T+ IIVAGGDGTL E VT
Sbjct: 74 GKARTLFEKNAAPILHLSGMVVTIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVT 133
Query: 363 GLLRRNDQA--NMFPVGVLPLGRTNSI 437
G+LRR D+A + P+G +PLG T+S+
Sbjct: 134 GVLRRTDEATFSKIPIGFIPLGETSSL 160
>AC099547-1|AAS07537.1| 162|Homo sapiens unknown protein.
Length = 162
Score = 118 bits (284), Expect = 9e-27
Identities = 59/125 (47%), Positives = 79/125 (63%), Gaps = 2/125 (1%)
Frame = +3
Query: 69 NILMRAACKEAAIYGEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQV 248
N+L RAAC+EA ++G L+P TV LNP A K KA+ FEK P V
Sbjct: 2 NLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACKGKARTLFEKNAAPILHLSGMDV 61
Query: 249 DVVQTASEGNAKEIVETLRGTEAIIVAGGDGTLSETVTGLLRRNDQA--NMFPVGVLPLG 422
+V+T EG AK+++E + T+ IIVAGGDGTL E VTG+LRR D+A + P+G +PLG
Sbjct: 62 TIVKTDYEGQAKKLLELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLG 121
Query: 423 RTNSI 437
T+S+
Sbjct: 122 ETSSL 126
>EF107108-1|ABK81123.1| 761|Homo sapiens sphingosine kinase-2
variant protein.
Length = 761
Score = 56.0 bits (129), Expect = 5e-08
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +3
Query: 111 GEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEI 290
GE + P + +++NP + A Q + + P +++QT + +A+E+
Sbjct: 232 GEITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHAREL 291
Query: 291 VETLRGTE--AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
V+ L +E I+ GDG L E + GLL R D +A PVG+LP G N++
Sbjct: 292 VQGLSLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNAL 344
>BC010671-1|AAH10671.1| 618|Homo sapiens SPHK2 protein protein.
Length = 618
Score = 56.0 bits (129), Expect = 5e-08
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +3
Query: 111 GEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEI 290
GE + P + +++NP + A Q + + P +++QT + +A+E+
Sbjct: 134 GEITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHAREL 193
Query: 291 VETLRGTE--AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
V+ L +E I+ GDG L E + GLL R D +A PVG+LP G N++
Sbjct: 194 VQGLSLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNAL 246
>BC006161-1|AAH06161.1| 654|Homo sapiens sphingosine kinase 2
protein.
Length = 654
Score = 56.0 bits (129), Expect = 5e-08
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +3
Query: 111 GEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEI 290
GE + P + +++NP + A Q + + P +++QT + +A+E+
Sbjct: 170 GEITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHAREL 229
Query: 291 VETLRGTE--AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
V+ L +E I+ GDG L E + GLL R D +A PVG+LP G N++
Sbjct: 230 VQGLSLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNAL 282
>AK000599-1|BAA91280.1| 354|Homo sapiens protein ( Homo sapiens
cDNA FLJ20592 fis, clone KAT08989. ).
Length = 354
Score = 56.0 bits (129), Expect = 5e-08
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +3
Query: 111 GEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEI 290
GE + P + +++NP + A Q + + P +++QT + +A+E+
Sbjct: 134 GEITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHAREL 193
Query: 291 VETLRGTE--AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
V+ L +E I+ GDG L E + GLL R D +A PVG+LP G N++
Sbjct: 194 VQGLSLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNAL 246
>AF245447-1|AAF74124.1| 618|Homo sapiens sphingosine kinase type 2
isoform protein.
Length = 618
Score = 56.0 bits (129), Expect = 5e-08
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +3
Query: 111 GEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEI 290
GE + P + +++NP + A Q + + P +++QT + +A+E+
Sbjct: 134 GEITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHAREL 193
Query: 291 VETLRGTE--AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
V+ L +E I+ GDG L E + GLL R D +A PVG+LP G N++
Sbjct: 194 VQGLSLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNAL 246
>BC030553-1|AAH30553.1| 470|Homo sapiens sphingosine kinase 1
protein.
Length = 470
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 100 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 159
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 160 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 202
>BC014439-1|AAH14439.1| 470|Homo sapiens sphingosine kinase 1
protein.
Length = 470
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 100 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 159
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 160 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 202
>BC009419-1|AAH09419.1| 398|Homo sapiens sphingosine kinase 1
protein.
Length = 398
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 28 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 87
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 88 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 130
>BC008040-1|AAH08040.1| 384|Homo sapiens SPHK1 protein protein.
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AY278525-1|AAP35060.1| 384|Homo sapiens sphingosine kinase 1
protein.
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AK023393-1|BAB14558.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ13331 fis, clone OVARC1001809, moderately
similar to Mus musculus sphingosine kinase (SPHK1a)
mRNA. ).
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AK022402-1|BAB14028.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ12340 fis, clone MAMMA1002268, moderately
similar to Mus musculus sphingosine kinase (SPHK1a)
mRNA. ).
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AF266756-1|AAF73470.1| 384|Homo sapiens sphingosine kinase
protein.
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AF238083-1|AAF73423.1| 384|Homo sapiens sphingosine kinase-1
protein.
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AF200328-1|AAG01980.1| 384|Homo sapiens sphingosine kinase
protein.
Length = 384
Score = 54.4 bits (125), Expect = 2e-07
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Frame = +3
Query: 141 PTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTE 314
P + V+LNP K KA Q F + +P ++ T +A+E+V E L +
Sbjct: 14 PCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWD 73
Query: 315 AIIVAGGDGTLSETVTGLLRRND--QANMFPVGVLPLGRTNSI 437
A++V GDG + E V GL+ R D A P+ LP G N++
Sbjct: 74 ALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNAL 116
>AY357073-1|AAR13670.1| 532|Homo sapiens ceramide kinase-like
protein isoform a protein.
Length = 532
Score = 50.8 bits (116), Expect = 2e-06
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Frame = +3
Query: 108 YGEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKE 287
+ + L P + ++LNP ++K++A Q + + EP + DV EG+A
Sbjct: 155 FKKILAGFPNRPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALS 214
Query: 288 IVE--TLRGTEAIIVAGGDGTLSETVTG-LLRRNDQANM------------FPVGVLPLG 422
+++ L+G + ++ GGDG+ SE LLR A M P+G++P G
Sbjct: 215 LLKECELQGFDGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 274
Query: 423 RTN 431
TN
Sbjct: 275 STN 277
>AJ640141-1|CAG26695.1| 532|Homo sapiens ceramide kinase-like
protein protein.
Length = 532
Score = 50.8 bits (116), Expect = 2e-06
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Frame = +3
Query: 108 YGEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKE 287
+ + L P + ++LNP ++K++A Q + + EP + DV EG+A
Sbjct: 155 FKKILAGFPNRPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALS 214
Query: 288 IVE--TLRGTEAIIVAGGDGTLSETVTG-LLRRNDQANM------------FPVGVLPLG 422
+++ L+G + ++ GGDG+ SE LLR A M P+G++P G
Sbjct: 215 LLKECELQGFDGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 274
Query: 423 RTN 431
TN
Sbjct: 275 STN 277
>AJ245504-1|CAB92131.1| 381|Homo sapiens sphingosine kinase
protein.
Length = 381
Score = 50.8 bits (116), Expect = 2e-06
Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Frame = +3
Query: 150 ITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV--ETLRGTEAII 323
+ V+LNP K KA Q F + +P ++ T +A+E+V E L +A++
Sbjct: 14 VLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALV 73
Query: 324 VAGGDGTLSETVTGLLRRND--QANMFPVGVLPLG 422
V GDG + E V GL+ R D A P+ LP G
Sbjct: 74 VMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAG 108
>AJ697855-1|CAG26977.1| 378|Homo sapiens ceramide kinase-like
protein protein.
Length = 378
Score = 47.6 bits (108), Expect = 2e-05
Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 15/123 (12%)
Frame = +3
Query: 108 YGEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKE 287
+ + L P + ++LNP ++K++A Q + + EP + DV E +A
Sbjct: 155 FKKILAGFPNRPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEEHALS 214
Query: 288 IVET--LRGTEAIIVAGGDGTLSETVTG-LLRRNDQANM------------FPVGVLPLG 422
+++ L+G + ++ GGDG+ SE LLR A M P+G++P G
Sbjct: 215 LLKECELQGFDGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAG 274
Query: 423 RTN 431
TN
Sbjct: 275 STN 277
>CR456404-1|CAG30290.1| 537|Homo sapiens bK29F11.1 protein.
Length = 537
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 214
>BC126940-1|AAI26941.1| 537|Homo sapiens ceramide kinase protein.
Length = 537
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 214
>AL118516-1|CAI17953.1| 537|Homo sapiens protein ( Human DNA
sequence from clone CTA-29F11 on chromosome 22. ).
Length = 537
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 214
>AL096766-1|CAI18819.1| 537|Homo sapiens protein ( Human DNA
sequence from clone RP6-59H18 on chromosome 22. ).
Length = 537
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 214
>AJ457828-1|CAD29884.1| 537|Homo sapiens putative lipid kinase
protein.
Length = 537
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 214
>AB079066-1|BAC01154.1| 537|Homo sapiens ceramide kinase protein.
Length = 537
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 214
>AB051433-1|BAB33316.1| 481|Homo sapiens KIAA1646 protein protein.
Length = 481
Score = 45.2 bits (102), Expect = 1e-04
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Frame = +3
Query: 114 EALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKEIV 293
E L + P + V +NP K + K+ +E+ P D++ T AKE +
Sbjct: 65 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 124
Query: 294 ETLR--GTEAIIVAGGDGTLSETVTGLLRRNDQA 389
+ + I+ GGDG SE + GL+ R ++
Sbjct: 125 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRS 158
>AY690329-1|AAW47988.1| 558|Homo sapiens ceramide kinase-like
protein isoform b protein.
Length = 558
Score = 31.5 bits (68), Expect(2) = 0.021
Identities = 15/63 (23%), Positives = 31/63 (49%)
Frame = +3
Query: 108 YGEALLPIERNPTVITVILNPVANKRKAKQEFEKYCEPXXXXXXXQVDVVQTASEGNAKE 287
+ + L P + ++LNP ++K++A Q + + EP + DV EG+A
Sbjct: 155 FKKILAGFPNRPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALS 214
Query: 288 IVE 296
+++
Sbjct: 215 LLK 217
Score = 25.0 bits (52), Expect(2) = 0.021
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 13/52 (25%)
Frame = +3
Query: 315 AIIVAGGDGTLSETVTG-LLRRNDQANM------------FPVGVLPLGRTN 431
+++ GGDG+ SE LLR A M P+G++P G TN
Sbjct: 252 SVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTN 303
>AF219939-1|AAF43006.1| 931|Homo sapiens diacylglycerol kinase iota
protein.
Length = 931
Score = 31.1 bits (67), Expect = 1.7
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Frame = +3
Query: 267 SEGNAKEIVETLRGTE--AIIVAGGDGTLSETVTGLLRRNDQANMFPVGVLPLGRTNSI 437
S+ K+ +E R I+ GGDGT+ + +L + PVGVLPLG N +
Sbjct: 276 SQEGPKDALELYRKVPNLRILACGGDGTVG-WILSILDELQLSPQPPVGVLPLGTGNDL 333
>AF061936-1|AAC62010.1| 1065|Homo sapiens diacylglycerol kinase iota
protein.
Length = 1065
Score = 31.1 bits (67), Expect = 1.7
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Frame = +3
Query: 267 SEGNAKEIVETLRGTE--AIIVAGGDGTLSETVTGLLRRNDQANMFPVGVLPLGRTNSI 437
S+ K+ +E R I+ GGDGT+ + +L + PVGVLPLG N +
Sbjct: 410 SQEGPKDALELYRKVPNLRILACGGDGTVG-WILSILDELQLSPQPPVGVLPLGTGNDL 467
>AB209167-1|BAD92404.1| 871|Homo sapiens diacylglycerol kinase,
iota variant protein.
Length = 871
Score = 31.1 bits (67), Expect = 1.7
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Frame = +3
Query: 267 SEGNAKEIVETLRGTE--AIIVAGGDGTLSETVTGLLRRNDQANMFPVGVLPLGRTNSI 437
S+ K+ +E R I+ GGDGT+ + +L + PVGVLPLG N +
Sbjct: 247 SQEGPKDALELYRKVPNLRILACGGDGTVG-WILSILDELQLSPQPPVGVLPLGTGNDL 304
>AJ697857-1|CAG26979.1| 241|Homo sapiens ceramide kinase-like
protein protein.
Length = 241
Score = 30.7 bits (66), Expect = 2.3
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 15/69 (21%)
Frame = +3
Query: 270 EGNAKEIVET--LRGTEAIIVAGGDGTLSETVTG-LLRRNDQANM------------FPV 404
EG+A +++ L+G + ++ GGDG+ SE LLR A M P+
Sbjct: 4 EGHALSLLKECELQGFDGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPL 63
Query: 405 GVLPLGRTN 431
G++P G TN
Sbjct: 64 GLIPAGSTN 72
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 57,773,957
Number of Sequences: 237096
Number of extensions: 1068074
Number of successful extensions: 3052
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 2874
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3028
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3545165828
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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