Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV32315
(587 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 99 6e-21
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 100 8e-21
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 100 8e-21
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 97 3e-20
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 89 1e-17
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 65 2e-10
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 65 2e-10
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 65 2e-10
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 65 2e-10
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 65 2e-10
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 65 2e-10
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 99 bits (238), Expect = 6e-21
Identities = 60/156 (38%), Positives = 83/156 (53%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 296
GRV+ SP+A++LA K I L +GTG G + D+
Sbjct: 353 GRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGM 412
Query: 297 XXX---TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEK 467
F D+P+S +R IA+RL +KQ+ PHY L + VN+ + L +RK +N+ L
Sbjct: 413 APVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSINVNMGEVLLVRKELNKILEGRS 472
Query: 468 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQ 575
K+SVNDFIIKA A AC +VP NS WM++ IRQ
Sbjct: 473 ---KISVNDFIIKASALACLKVPEANSSWMDTVIRQ 505
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 99.5 bits (237), Expect = 8e-21
Identities = 60/156 (38%), Positives = 83/156 (53%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 296
GRV+ SP+A++LA K I L +GTG G + D+
Sbjct: 321 GRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGM 380
Query: 297 XXX---TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEK 467
F D+P+S +R IA+RL +KQ+ PHY L + VN+ + L +RK +N+ L
Sbjct: 381 APVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS 440
Query: 468 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQ 575
K+SVNDFIIKA A AC +VP NS WM++ IRQ
Sbjct: 441 ---KISVNDFIIKASALACLKVPEANSSWMDTVIRQ 473
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 99.5 bits (237), Expect = 8e-21
Identities = 60/156 (38%), Positives = 83/156 (53%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 296
GRV+ SP+A++LA K I L +GTG G + D+
Sbjct: 353 GRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGM 412
Query: 297 XXX---TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEK 467
F D+P+S +R IA+RL +KQ+ PHY L + VN+ + L +RK +N+ L
Sbjct: 413 APVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS 472
Query: 468 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQ 575
K+SVNDFIIKA A AC +VP NS WM++ IRQ
Sbjct: 473 ---KISVNDFIIKASALACLKVPEANSSWMDTVIRQ 505
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 97.5 bits (232), Expect = 3e-20
Identities = 59/156 (37%), Positives = 82/156 (52%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 296
GRV+ SP+A++LA K I L +GTG G + D+
Sbjct: 17 GRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGM 76
Query: 297 XXX---TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEK 467
F D+P+S +R IA+RL +KQ+ PHY L + VN+ + L +RK +N+ L
Sbjct: 77 APVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS 136
Query: 468 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQ 575
K+SVNDFIIK A AC +VP NS WM++ IRQ
Sbjct: 137 ---KISVNDFIIKRSALACLKVPEANSSWMDTVIRQ 169
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 88.6 bits (210), Expect = 1e-17
Identities = 57/156 (36%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 296
GRV+ P+A++LA K I L +GTG G + D+
Sbjct: 320 GRVFVDPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGM 379
Query: 297 XXX---TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEK 467
F D+P+S +R IA+RL +KQ+ PHY L ++ + L +RK +N+ L
Sbjct: 380 APVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYL-LSCKYGEVLLVRKELNKILEGRS 438
Query: 468 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQ 575
K+SVNDFIIKA A AC +VP NS WM++ IRQ
Sbjct: 439 ---KISVNDFIIKASALACLKVPEANSSWMDTVIRQ 471
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +3
Query: 306 TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEKADVKVS 485
TF ++P S +R IAKRLT +K + PH ++ L +R+ + K D+KVS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 327
Query: 486 VNDFIIKAVAAACKRVPTVNSHW 554
VNDFIIKA A K++P VN W
Sbjct: 328 VNDFIIKAAAVTLKQMPDVNVSW 350
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +3
Query: 306 TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEKADVKVS 485
TF ++P S +R IAKRLT +K + PH ++ L +R+ + K D+KVS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 327
Query: 486 VNDFIIKAVAAACKRVPTVNSHW 554
VNDFIIKA A K++P VN W
Sbjct: 328 VNDFIIKAAAVTLKQMPDVNVSW 350
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +3
Query: 306 TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEKADVKVS 485
TF ++P S +R IAKRLT +K + PH ++ L +R+ + K D+KVS
Sbjct: 148 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 201
Query: 486 VNDFIIKAVAAACKRVPTVNSHW 554
VNDFIIKA A K++P VN W
Sbjct: 202 VNDFIIKAAAVTLKQMPDVNVSW 224
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +3
Query: 306 TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEKADVKVS 485
TF ++P S +R IAKRLT +K + PH ++ L +R+ + K D+KVS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 327
Query: 486 VNDFIIKAVAAACKRVPTVNSHW 554
VNDFIIKA A K++P VN W
Sbjct: 328 VNDFIIKAAAVTLKQMPDVNVSW 350
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +3
Query: 306 TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEKADVKVS 485
TF ++P S +R IAKRLT +K + PH ++ L +R+ + K D+KVS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 327
Query: 486 VNDFIIKAVAAACKRVPTVNSHW 554
VNDFIIKA A K++P VN W
Sbjct: 328 VNDFIIKAAAVTLKQMPDVNVSW 350
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/83 (42%), Positives = 48/83 (57%)
Frame = +3
Query: 306 TFVDLPLSGMRETIAKRLTAAKQSXPHYQLXVTVNVEKTLAMRKLVNERLASEKADVKVS 485
TF ++P S +R IAKRLT +K + PH ++ L +R+ + K D+KVS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 327
Query: 486 VNDFIIKAVAAACKRVPTVNSHW 554
VNDFIIKA A K++P VN W
Sbjct: 328 VNDFIIKAAAVTLKQMPDVNVSW 350
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 53,943,722
Number of Sequences: 237096
Number of extensions: 769076
Number of successful extensions: 1197
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 1143
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1182
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6155099854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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