Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV31456
(732 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein. 38 0.049
BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein. 38 0.049
AL355355-6|CAI16550.1| 571|Homo sapiens optineurin protein. 38 0.049
AL355355-5|CAI16549.1| 577|Homo sapiens optineurin protein. 38 0.049
AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3 pr... 38 0.049
AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2 pr... 38 0.049
AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1 pr... 38 0.049
AF283527-1|AAG00497.1| 577|Homo sapiens FIP2 protein. 38 0.049
AF061034-1|AAC16046.1| 577|Homo sapiens FIP2 protein. 38 0.049
BC048299-1|AAH48299.1| 545|Homo sapiens SPATS2 protein protein. 32 1.8
BC017977-1|AAH17977.1| 360|Homo sapiens Unknown (protein for IM... 32 1.8
AK023202-1|BAB14460.1| 545|Homo sapiens protein ( Homo sapiens ... 32 1.8
AK023179-1|BAB14448.1| 476|Homo sapiens protein ( Homo sapiens ... 32 1.8
AB075515-1|BAE45760.1| 545|Homo sapiens putative protein produc... 32 1.8
DQ529299-1|ABF71985.1| 431|Homo sapiens TTG1A protein. 30 7.4
DQ323046-1|ABC50092.1| 454|Homo sapiens TTG1 protein. 30 7.4
BC003397-1|AAH03397.2| 454|Homo sapiens chromosome 1 open readi... 30 7.4
AY854248-1|AAW30011.1| 454|Homo sapiens odorant response abnorm... 30 7.4
AL596220-3|CAI13121.1| 454|Homo sapiens chromosome 1 open readi... 30 7.4
AK026086-1|BAB15356.1| 373|Homo sapiens protein ( Homo sapiens ... 30 7.4
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 30 9.8
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 30 9.8
AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens ... 30 9.8
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 30 9.8
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 30 9.8
>BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein.
Length = 571
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AL355355-6|CAI16550.1| 571|Homo sapiens optineurin protein.
Length = 571
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AL355355-5|CAI16549.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3
protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2
protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1
protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AF283527-1|AAG00497.1| 577|Homo sapiens FIP2 protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>AF061034-1|AAC16046.1| 577|Homo sapiens FIP2 protein.
Length = 577
Score = 37.5 bits (83), Expect = 0.049
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 475 DDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMDED 624
D + EEL ++ ELL EN LKE +K NN +MK +F +++ E E+
Sbjct: 33 DTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEE 82
>BC048299-1|AAH48299.1| 545|Homo sapiens SPATS2 protein protein.
Length = 545
Score = 32.3 bits (70), Expect = 1.8
Identities = 27/113 (23%), Positives = 48/113 (42%)
Frame = +1
Query: 280 GTSPGSSLDLKCNGIHNGENSLDNTQIEEAMKDLPAEANMAFKAHFKLGDCPSPASMMVA 459
G S + L + IHN + Q A K L ++ + D P S ++
Sbjct: 182 GVSDFETKSLTMHSIHNSQ------QPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLS 235
Query: 460 STMITDDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMD 618
S + +KS ++LQ+ L +++KE + + MK+ F + SC D +
Sbjct: 236 SNI---EKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDRE 285
>BC017977-1|AAH17977.1| 360|Homo sapiens Unknown (protein for
IMAGE:4697938) protein.
Length = 360
Score = 32.3 bits (70), Expect = 1.8
Identities = 14/31 (45%), Positives = 21/31 (67%)
Frame = +1
Query: 484 STEELQKRFGELLDENLILKETLKQNNDSMK 576
S EEL+ RF L DEN++LK+ ++ D +K
Sbjct: 46 SREELEDRFLRLHDENILLKQHARKQEDKIK 76
>AK023202-1|BAB14460.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13140 fis, clone NT2RP3003204. ).
Length = 545
Score = 32.3 bits (70), Expect = 1.8
Identities = 27/113 (23%), Positives = 48/113 (42%)
Frame = +1
Query: 280 GTSPGSSLDLKCNGIHNGENSLDNTQIEEAMKDLPAEANMAFKAHFKLGDCPSPASMMVA 459
G S + L + IHN + Q A K L ++ + D P S ++
Sbjct: 182 GVSDFETKSLTMHSIHNSQ------QPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLS 235
Query: 460 STMITDDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMD 618
S + +KS ++LQ+ L +++KE + + MK+ F + SC D +
Sbjct: 236 SNI---EKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDRE 285
>AK023179-1|BAB14448.1| 476|Homo sapiens protein ( Homo sapiens
cDNA FLJ13117 fis, clone NT2RP3002660. ).
Length = 476
Score = 32.3 bits (70), Expect = 1.8
Identities = 27/113 (23%), Positives = 48/113 (42%)
Frame = +1
Query: 280 GTSPGSSLDLKCNGIHNGENSLDNTQIEEAMKDLPAEANMAFKAHFKLGDCPSPASMMVA 459
G S + L + IHN + Q A K L ++ + D P S ++
Sbjct: 113 GVSDFETKSLTMHSIHNSQ------QPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLS 166
Query: 460 STMITDDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMD 618
S + +KS ++LQ+ L +++KE + + MK+ F + SC D +
Sbjct: 167 SNI---EKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDRE 216
>AB075515-1|BAE45760.1| 545|Homo sapiens putative protein product
of Nbla00526 protein.
Length = 545
Score = 32.3 bits (70), Expect = 1.8
Identities = 27/113 (23%), Positives = 48/113 (42%)
Frame = +1
Query: 280 GTSPGSSLDLKCNGIHNGENSLDNTQIEEAMKDLPAEANMAFKAHFKLGDCPSPASMMVA 459
G S + L + IHN + Q A K L ++ + D P S ++
Sbjct: 182 GVSDFETKSLTMHSIHNSQ------QPRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLS 235
Query: 460 STMITDDKSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDMD 618
S + +KS ++LQ+ L +++KE + + MK+ F + SC D +
Sbjct: 236 SNI---EKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDRE 285
>DQ529299-1|ABF71985.1| 431|Homo sapiens TTG1A protein.
Length = 431
Score = 30.3 bits (65), Expect = 7.4
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 433 PSPASMMVASTMITDDKSTEELQKRFGELLDENLILK--ETLKQNNDS-MKEQFLLIASC 603
P P S ++ DD+S EE++ F E+LD + ++ E ++ N + M AS
Sbjct: 326 PLPGSTVMLRDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASL 385
Query: 604 QEDMDEDP 627
DE P
Sbjct: 386 DNTDDEQP 393
>DQ323046-1|ABC50092.1| 454|Homo sapiens TTG1 protein.
Length = 454
Score = 30.3 bits (65), Expect = 7.4
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 433 PSPASMMVASTMITDDKSTEELQKRFGELLDENLILK--ETLKQNNDS-MKEQFLLIASC 603
P P S ++ DD+S EE++ F E+LD + ++ E ++ N + M AS
Sbjct: 349 PLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASL 408
Query: 604 QEDMDEDP 627
DE P
Sbjct: 409 DNTDDEQP 416
>BC003397-1|AAH03397.2| 454|Homo sapiens chromosome 1 open reading
frame 27 protein.
Length = 454
Score = 30.3 bits (65), Expect = 7.4
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 433 PSPASMMVASTMITDDKSTEELQKRFGELLDENLILK--ETLKQNNDS-MKEQFLLIASC 603
P P S ++ DD+S EE++ F E+LD + ++ E ++ N + M AS
Sbjct: 349 PLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASL 408
Query: 604 QEDMDEDP 627
DE P
Sbjct: 409 DNTDDEQP 416
>AY854248-1|AAW30011.1| 454|Homo sapiens odorant response abnormal
4 protein protein.
Length = 454
Score = 30.3 bits (65), Expect = 7.4
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 433 PSPASMMVASTMITDDKSTEELQKRFGELLDENLILK--ETLKQNNDS-MKEQFLLIASC 603
P P S ++ DD+S EE++ F E+LD + ++ E ++ N + M AS
Sbjct: 349 PLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASL 408
Query: 604 QEDMDEDP 627
DE P
Sbjct: 409 DNTDDEQP 416
>AL596220-3|CAI13121.1| 454|Homo sapiens chromosome 1 open reading
frame 27 protein.
Length = 454
Score = 30.3 bits (65), Expect = 7.4
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 433 PSPASMMVASTMITDDKSTEELQKRFGELLDENLILK--ETLKQNNDS-MKEQFLLIASC 603
P P S ++ DD+S EE++ F E+LD + ++ E ++ N + M AS
Sbjct: 349 PLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASL 408
Query: 604 QEDMDEDP 627
DE P
Sbjct: 409 DNTDDEQP 416
>AK026086-1|BAB15356.1| 373|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22433 fis, clone HRC09172. ).
Length = 373
Score = 30.3 bits (65), Expect = 7.4
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Frame = +1
Query: 433 PSPASMMVASTMITDDKSTEELQKRFGELLDENLILK--ETLKQNNDS-MKEQFLLIASC 603
P P S ++ DD+S EE++ F E+LD + ++ E ++ N + M AS
Sbjct: 268 PLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASL 327
Query: 604 QEDMDEDP 627
DE P
Sbjct: 328 DNTDDEQP 335
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 29.9 bits (64), Expect = 9.8
Identities = 12/45 (26%), Positives = 26/45 (57%)
Frame = +1
Query: 481 KSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDM 615
K E++ + F ++ D+N ILK L+ + +K +++ +A + M
Sbjct: 888 KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKM 932
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 29.9 bits (64), Expect = 9.8
Identities = 12/45 (26%), Positives = 26/45 (57%)
Frame = +1
Query: 481 KSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDM 615
K E++ + F ++ D+N ILK L+ + +K +++ +A + M
Sbjct: 888 KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKM 932
>AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens
cDNA FLJ10128 fis, clone HEMBA1002997, weakly similar to
CENTROMERIC PROTEIN E. ).
Length = 535
Score = 29.9 bits (64), Expect = 9.8
Identities = 12/45 (26%), Positives = 26/45 (57%)
Frame = +1
Query: 481 KSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDM 615
K E++ + F ++ D+N ILK L+ + +K +++ +A + M
Sbjct: 236 KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKM 280
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 29.9 bits (64), Expect = 9.8
Identities = 12/45 (26%), Positives = 26/45 (57%)
Frame = +1
Query: 481 KSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDM 615
K E++ + F ++ D+N ILK L+ + +K +++ +A + M
Sbjct: 888 KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKM 932
>AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein.
Length = 1416
Score = 29.9 bits (64), Expect = 9.8
Identities = 12/45 (26%), Positives = 26/45 (57%)
Frame = +1
Query: 481 KSTEELQKRFGELLDENLILKETLKQNNDSMKEQFLLIASCQEDM 615
K E++ + F ++ D+N ILK L+ + +K +++ +A + M
Sbjct: 888 KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKM 932
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,003,547
Number of Sequences: 237096
Number of extensions: 1812716
Number of successful extensions: 4772
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 4563
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4757
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8679165170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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