Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30919
(744 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 290 3e-78
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 290 3e-78
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 290 3e-78
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 290 3e-78
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 274 2e-73
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 274 2e-73
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 274 2e-73
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 274 2e-73
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 274 2e-73
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 274 2e-73
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 274 2e-73
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 272 9e-73
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 270 3e-72
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 242 8e-64
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 234 2e-61
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 128 3e-29
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 37 0.088
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 290 bits (712), Expect = 3e-78
Identities = 134/196 (68%), Positives = 157/196 (80%), Gaps = 1/196 (0%)
Frame = +3
Query: 159 RNYGTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 338
R + KR+ AKPVVEMDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 339 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 518
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 519 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTP 695
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 696 GVAMGMYNTDESIRSF 743
GV MGMYNTDESI F
Sbjct: 216 GVGMGMYNTDESISGF 231
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 290 bits (712), Expect = 3e-78
Identities = 134/196 (68%), Positives = 157/196 (80%), Gaps = 1/196 (0%)
Frame = +3
Query: 159 RNYGTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 338
R + KR+ AKPVVEMDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 339 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 518
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 519 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTP 695
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 696 GVAMGMYNTDESIRSF 743
GV MGMYNTDESI F
Sbjct: 216 GVGMGMYNTDESISGF 231
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 290 bits (712), Expect = 3e-78
Identities = 134/196 (68%), Positives = 157/196 (80%), Gaps = 1/196 (0%)
Frame = +3
Query: 159 RNYGTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 338
R + KR+ AKPVVEMDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 339 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 518
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 519 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTP 695
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 696 GVAMGMYNTDESIRSF 743
GV MGMYNTDESI F
Sbjct: 216 GVGMGMYNTDESISGF 231
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 290 bits (712), Expect = 3e-78
Identities = 134/196 (68%), Positives = 157/196 (80%), Gaps = 1/196 (0%)
Frame = +3
Query: 159 RNYGTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 338
R + KR+ AKPVVEMDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 339 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 518
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 519 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTP 695
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 696 GVAMGMYNTDESIRSF 743
GV MGMYNTDESI F
Sbjct: 216 GVGMGMYNTDESISGF 231
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 274 bits (673), Expect = 2e-73
Identities = 127/188 (67%), Positives = 156/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 272 bits (667), Expect = 9e-73
Identities = 127/188 (67%), Positives = 151/188 (80%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKT--PGVAMGMYN 719
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + L GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 270 bits (663), Expect = 3e-72
Identities = 125/188 (66%), Positives = 155/188 (82%), Gaps = 2/188 (1%)
Frame = +3
Query: 186 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 365
++ VVEM GDEMTRI+W IKE+LI PYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 366 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 545
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 546 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYN 719
+PI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 720 TDESIRSF 743
D+SI F
Sbjct: 185 QDKSIEDF 192
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 242 bits (593), Expect = 8e-64
Identities = 112/163 (68%), Positives = 137/163 (84%), Gaps = 2/163 (1%)
Frame = +3
Query: 261 LIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLK 440
LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+KCATITPDE+RVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 441 KMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKP 620
+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP P
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 621 GKVELVYTTRDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 743
GKVE+ YT DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 163
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 234 bits (573), Expect = 2e-61
Identities = 108/155 (69%), Positives = 125/155 (80%), Gaps = 1/155 (0%)
Frame = +3
Query: 282 VDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPN 461
V YFDLGLP+RD TDDQVTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPN
Sbjct: 44 VQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPN 103
Query: 462 GTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVY 641
GTIRNI GGTVFREPI+C++IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+
Sbjct: 104 GTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 163
Query: 642 TTRDGT-TERRVLYDFKTPGVAMGMYNTDESIRSF 743
T +DG+ + +Y+F GV MGMYNTDESI F
Sbjct: 164 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGF 198
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 128 bits (308), Expect = 3e-29
Identities = 59/93 (63%), Positives = 74/93 (79%), Gaps = 2/93 (2%)
Frame = +3
Query: 471 RNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTR 650
RNILGGTVF E I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 651 DGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSF 743
DGT + ++++F+ GVAMGMYN D+SI F
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDF 93
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 36.7 bits (81), Expect = 0.088
Identities = 16/43 (37%), Positives = 21/43 (48%)
Frame = +3
Query: 525 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRD 653
PR GW +P + H H DQ +P PGK +L+ RD
Sbjct: 20 PRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLLEQARD 62
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,225,077
Number of Sequences: 237096
Number of extensions: 2393591
Number of successful extensions: 5405
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5252
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5389
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8903143626
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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