Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30902
(696 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 133 5e-31
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 133 5e-31
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 133 5e-31
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 133 5e-31
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 118 3e-26
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 111 3e-24
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 86 1e-16
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 86 1e-16
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 84 5e-16
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 84 5e-16
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 84 5e-16
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 84 5e-16
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 58 4e-08
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 57 7e-08
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 57 7e-08
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 57 7e-08
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 56 1e-07
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 56 1e-07
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 56 1e-07
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 56 1e-07
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 56 2e-07
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 56 2e-07
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 56 2e-07
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 56 2e-07
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 56 2e-07
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 56 2e-07
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 56 2e-07
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 56 2e-07
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 55 2e-07
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 55 2e-07
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 55 2e-07
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 55 2e-07
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 55 2e-07
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 55 2e-07
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 55 2e-07
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 55 3e-07
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 55 3e-07
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 54 4e-07
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 54 4e-07
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 54 4e-07
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 54 4e-07
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 54 4e-07
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 54 4e-07
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 54 4e-07
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 54 4e-07
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 54 5e-07
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 54 6e-07
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 54 6e-07
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 53 9e-07
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 53 9e-07
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 53 9e-07
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 53 9e-07
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 53 9e-07
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 53 9e-07
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 53 9e-07
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 53 9e-07
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 53 9e-07
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 53 1e-06
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 52 3e-06
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 51 3e-06
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 51 5e-06
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 50 1e-05
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 50 1e-05
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 50 1e-05
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 49 2e-05
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 49 2e-05
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 49 2e-05
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 49 2e-05
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 49 2e-05
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 46 1e-04
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 46 1e-04
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 46 1e-04
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 46 1e-04
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 46 1e-04
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 46 1e-04
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 46 1e-04
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 46 1e-04
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 46 1e-04
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 46 1e-04
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 46 1e-04
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 46 1e-04
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 46 1e-04
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 46 1e-04
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 46 1e-04
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 45 2e-04
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 45 2e-04
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 45 2e-04
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 45 2e-04
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 45 2e-04
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 45 3e-04
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 45 3e-04
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 44 7e-04
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 44 7e-04
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 44 7e-04
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 44 7e-04
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 43 0.001
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 43 0.001
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 43 0.001
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 43 0.001
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 43 0.001
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 43 0.001
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 43 0.001
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 43 0.001
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 43 0.001
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 43 0.001
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 43 0.001
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 43 0.001
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 43 0.001
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 43 0.001
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 43 0.001
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 43 0.001
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 43 0.001
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 43 0.001
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 43 0.001
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 42 0.002
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 42 0.002
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 42 0.002
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 42 0.002
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 42 0.002
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 42 0.002
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 42 0.002
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.002
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 42 0.002
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.002
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 42 0.002
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 42 0.002
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.002
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 42 0.002
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 42 0.002
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.002
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 42 0.002
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 42 0.002
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 42 0.002
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 42 0.002
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 42 0.002
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 42 0.002
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 42 0.002
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 42 0.002
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 42 0.002
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 42 0.002
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 42 0.002
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 42 0.002
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 42 0.003
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 42 0.003
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 42 0.003
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 41 0.005
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 40 0.006
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 40 0.006
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 40 0.006
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.008
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.008
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.008
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.008
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 40 0.008
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 40 0.008
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 40 0.008
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 40 0.008
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 40 0.011
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 40 0.011
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 40 0.011
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 40 0.011
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 40 0.011
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 39 0.020
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 39 0.020
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 39 0.020
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 39 0.020
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 39 0.020
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 39 0.020
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 39 0.020
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 39 0.020
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 38 0.026
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 38 0.034
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 38 0.034
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 38 0.045
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 38 0.045
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 38 0.045
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 38 0.045
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 38 0.045
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 37 0.060
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 37 0.060
AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid ... 37 0.060
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 37 0.060
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 36 0.10
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 36 0.10
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 36 0.10
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 36 0.10
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 36 0.10
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 36 0.14
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 36 0.14
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 36 0.14
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 36 0.14
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 36 0.14
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.14
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 36 0.14
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.14
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.14
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.14
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 36 0.18
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 36 0.18
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 36 0.18
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 35 0.24
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 35 0.24
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 35 0.24
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 35 0.24
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 35 0.24
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 35 0.24
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 35 0.24
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 35 0.24
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 35 0.24
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 35 0.24
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 35 0.24
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 35 0.24
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 35 0.24
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 35 0.24
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 35 0.24
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 35 0.32
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.32
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.32
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 35 0.32
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 35 0.32
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.32
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.32
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 34 0.42
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 34 0.42
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 34 0.42
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 34 0.42
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 34 0.42
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 34 0.42
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 34 0.42
BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein protein. 34 0.56
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 34 0.56
AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid d... 34 0.56
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 33 0.74
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 33 0.74
X55997-1|CAA39469.1| 373|Homo sapiens 3-beta-hydroxy-5-ene ster... 33 0.97
X53321-1|CAA37408.1| 373|Homo sapiens Hydroxysteroid dehydrogen... 33 0.97
S45679-1|AAB23543.1| 373|Homo sapiens 3 beta-hydroxysteroid deh... 33 0.97
M63397-1|AAA51662.1| 373|Homo sapiens 3-beta-hydroxysteroid deh... 33 0.97
M38180-1|AAA51831.1| 373|Homo sapiens 3-beta-hydroxysteroid deh... 33 0.97
M35493-1|AAA51538.1| 373|Homo sapiens HSD3B protein. 33 0.97
M27137-1|AAA36015.1| 373|Homo sapiens protein ( Human 3 beta-hy... 33 0.97
BC031999-1|AAH31999.1| 373|Homo sapiens hydroxy-delta-5-steroid... 33 0.97
AL121995-3|CAI23359.1| 375|Homo sapiens hydroxy-delta-5-steroid... 33 0.97
AK024447-1|BAB15737.1| 145|Homo sapiens FLJ00037 protein protein. 33 0.97
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 33 1.3
AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain deh... 33 1.3
AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein. 33 1.3
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 33 1.3
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 32 1.7
M28392-1|AAA36001.1| 353|Homo sapiens protein ( Human 3-beta-hy... 32 1.7
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 32 1.7
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 32 1.7
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 32 1.7
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 32 1.7
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 32 1.7
AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid d... 32 1.7
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 32 2.2
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 32 2.2
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 32 2.2
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 32 2.2
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 32 2.2
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 32 2.2
AF336861-1|AAK64603.1| 396|Homo sapiens NOGO-interacting mitoch... 32 2.2
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 32 2.2
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 31 3.0
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 31 3.9
BC112935-1|AAI12936.1| 1699|Homo sapiens QSER1 protein protein. 30 6.9
BC006399-1|AAH06399.2| 396|Homo sapiens reticulon 4 interacting... 30 9.1
AY063761-1|AAL40856.1| 396|Homo sapiens NOGO-interacting mitoch... 30 9.1
AL390074-5|CAH72095.1| 396|Homo sapiens reticulon 4 interacting... 30 9.1
AK095207-1|BAC04499.1| 296|Homo sapiens protein ( Homo sapiens ... 30 9.1
AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein. 30 9.1
AF165514-1|AAF86644.1| 111|Homo sapiens 17-beta-hydroxysteroid ... 30 9.1
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 133 bits (322), Expect = 5e-31
Identities = 65/187 (34%), Positives = 112/187 (59%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
DV D++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 675
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 676 CFGATDT 696
C G +T
Sbjct: 182 CPGFVNT 188
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 133 bits (322), Expect = 5e-31
Identities = 65/187 (34%), Positives = 112/187 (59%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
DV D++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 675
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 676 CFGATDT 696
C G +T
Sbjct: 182 CPGFVNT 188
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 133 bits (322), Expect = 5e-31
Identities = 65/187 (34%), Positives = 112/187 (59%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
DV D++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 675
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 676 CFGATDT 696
C G +T
Sbjct: 182 CPGFVNT 188
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 133 bits (322), Expect = 5e-31
Identities = 65/187 (34%), Positives = 112/187 (59%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
DV D++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 675
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 676 CFGATDT 696
C G +T
Sbjct: 182 CPGFVNT 188
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 118 bits (283), Expect = 3e-26
Identities = 56/161 (34%), Positives = 98/161 (60%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
DV D++ + F V + G LD+++NNA + N K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNK--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFS 618
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 111 bits (266), Expect = 3e-24
Identities = 52/140 (37%), Positives = 90/140 (64%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
DV D++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 496 MGKQNGGKGGTVLNISSVAA 555
M KQNGG+GG ++N+SS+AA
Sbjct: 122 MSKQNGGEGGIIINMSSLAA 141
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/200 (27%), Positives = 102/200 (51%), Gaps = 8/200 (4%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
ME W+ ++ L+TGA+ GIG V R ++++G+K V + L E + P ++
Sbjct: 6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNI-EELAAECKSAGYPGTL 64
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTA 462
Y+CD+++EE L +F ++++ +D+ INNA +++ S +K ++NV A
Sbjct: 65 IPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAA--LCQSHMFPIYFGTKSAVLQFSNCIGLE 636
L T +A + M K+ G ++NI+S++ + + Y TK AV + + E
Sbjct: 125 LSICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQE 183
Query: 637 EHYAKSGVRVLSICFGATDT 696
A++ +R I G +T
Sbjct: 184 LREAQTHIRATCISPGVVET 203
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/200 (27%), Positives = 102/200 (51%), Gaps = 8/200 (4%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
ME W+ ++ L+TGA+ GIG V R ++++G+K V + L E + P ++
Sbjct: 6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNI-EELAAECKSAGYPGTL 64
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTA 462
Y+CD+++EE L +F ++++ +D+ INNA +++ S +K ++NV A
Sbjct: 65 IPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAA--LCQSHMFPIYFGTKSAVLQFSNCIGLE 636
L T +A + M K+ G ++NI+S++ + + Y TK AV + + E
Sbjct: 125 LSICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQE 183
Query: 637 EHYAKSGVRVLSICFGATDT 696
A++ +R I G +T
Sbjct: 184 LREAQTHIRATCISPGVVET 203
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 83.8 bits (198), Expect = 5e-16
Identities = 68/193 (35%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
Frame = +1
Query: 130 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFY 309
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P +V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 468
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 646 AKSGVRVLSICFG 684
+ GVRV I G
Sbjct: 173 SPYGVRVNCISPG 185
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 83.8 bits (198), Expect = 5e-16
Identities = 68/193 (35%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
Frame = +1
Query: 130 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFY 309
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P +V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 468
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 646 AKSGVRVLSICFG 684
+ GVRV I G
Sbjct: 173 SPYGVRVNCISPG 185
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 83.8 bits (198), Expect = 5e-16
Identities = 68/193 (35%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
Frame = +1
Query: 130 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFY 309
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P +V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 468
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 646 AKSGVRVLSICFG 684
+ GVRV I G
Sbjct: 173 SPYGVRVNCISPG 185
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 83.8 bits (198), Expect = 5e-16
Identities = 68/193 (35%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
Frame = +1
Query: 130 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFY 309
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P +V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 468
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 646 AKSGVRVLSICFG 684
+ GVRV I G
Sbjct: 173 SPYGVRVNCISPG 185
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 57.6 bits (133), Expect = 4e-08
Identities = 52/188 (27%), Positives = 87/188 (46%), Gaps = 7/188 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V+ Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVRAYTC 97
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 477
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK-S 654
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 655 GVRVLSIC 678
G++ +C
Sbjct: 215 GIKTTIVC 222
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 56.8 bits (131), Expect = 7e-08
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAYTC 97
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 477
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK-S 654
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 655 GVRVLSIC 678
G++ +C
Sbjct: 215 GIKTTIVC 222
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 56.8 bits (131), Expect = 7e-08
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAYTC 97
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 477
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK-S 654
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 655 GVRVLSIC 678
G++ +C
Sbjct: 215 GIKTTIVC 222
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 56.8 bits (131), Expect = 7e-08
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAYTC 97
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 477
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK-S 654
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 655 GVRVLSIC 678
G++ +C
Sbjct: 215 GIKTTIVC 222
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 474
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 474
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 474
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 15 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 70
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 474
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 71 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 130
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 131 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 185
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 186 NIRVNCLAPGLIKT 199
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA 179
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 471
+CDV D ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 472 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 646 AKSGVR 663
K G+R
Sbjct: 229 GKYGMR 234
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 471
+CDV D ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 472 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 646 AKSGVR 663
K G+R
Sbjct: 229 GKYGMR 234
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 471
+CDV D ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 472 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 646 AKSGVR 663
K G+R
Sbjct: 229 GKYGMR 234
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 471
+CDV D ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 472 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 646 AKSGVR 663
K G+R
Sbjct: 229 GKYGMR 234
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 471
+CDV D ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 472 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 646 AKSGVR 663
K G+R
Sbjct: 229 GKYGMR 234
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 55.2 bits (127), Expect = 2e-07
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 474
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 MVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 471
+CDV D ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 472 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 646 AKSGVR 663
K G+R
Sbjct: 229 GKYGMR 234
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 54.8 bits (126), Expect = 3e-07
Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 7/194 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE KY ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KY--PGIQTRVL 57
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVIN------NAAIMNDSYKSYKKQIDINVTALVTGT 477
DVT + + D NE LDV+ N + +++ K + +++NV ++
Sbjct: 58 DVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL-M 112
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFP-IYFGTKSAVLQFSNCIGLEEHYAKS 654
+KA + K K G ++N+SSVA+ + + +Y TK+AV+ + + + + +
Sbjct: 113 IKA--FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQ 168
Query: 655 GVRVLSICFGATDT 696
G+R +C G DT
Sbjct: 169 GIRCNCVCPGTVDT 182
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 54.8 bits (126), Expect = 3e-07
Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 7/194 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE KY ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KY--PGIQTRVL 57
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVIN------NAAIMNDSYKSYKKQIDINVTALVTGT 477
DVT + + D NE LDV+ N + +++ K + +++NV ++
Sbjct: 58 DVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL-M 112
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFP-IYFGTKSAVLQFSNCIGLEEHYAKS 654
+KA + K K G ++N+SSVA+ + + +Y TK+AV+ + + + + +
Sbjct: 113 IKA--FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQ 168
Query: 655 GVRVLSICFGATDT 696
G+R +C G DT
Sbjct: 169 GIRCNCVCPGTVDT 182
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 54.4 bits (125), Expect = 4e-07
Identities = 54/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 33 KVALATASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 474
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 15/205 (7%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ + A G+RV++I G T
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGT 203
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 54.0 bits (124), Expect = 5e-07
Identities = 45/188 (23%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE + V K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRVLDVT-KKK 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
+ +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFASEVERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA--F 116
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFP-IYFGTKSAVLQFSNCIGLEEHYAKSGVRVLS 672
+ K K G ++N+SSVA+ + + +Y TK+AV+ + + + + + G+R
Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQGIRCNC 174
Query: 673 ICFGATDT 696
+C G DT
Sbjct: 175 VCPGTVDT 182
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 53.6 bits (123), Expect = 6e-07
Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINV 456
D++D + E+ +L V+INNA +M Y ++++
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHI 146
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 53.6 bits (123), Expect = 6e-07
Identities = 45/188 (23%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE + V K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRVLDVT-KKK 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
+ +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFASEVERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA--F 116
Query: 496 MGKQNGGKGGTVLNISSVAALCQSHMFP-IYFGTKSAVLQFSNCIGLEEHYAKSGVRVLS 672
+ K K G ++N+SSVA+ + + +Y TK+AV+ + + + + + G+R
Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAAD--FIQQGIRCNC 174
Query: 673 ICFGATDT 696
+C G DT
Sbjct: 175 VCPGTVDT 182
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 53.2 bits (122), Expect = 9e-07
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G SVK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTG-RSVKIIQA 105
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 483
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 484 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
+++ K + G +LNISS AL ++ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 53.2 bits (122), Expect = 9e-07
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G SVK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTG-RSVKIIQA 105
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 483
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 484 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
+++ K + G +LNISS AL ++ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 53.2 bits (122), Expect = 9e-07
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G SVK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTG-RSVKIIQA 105
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 483
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 484 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
+++ K + G +LNISS AL ++ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 53.2 bits (122), Expect = 9e-07
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G SVK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTG-RSVKIIQA 105
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 483
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 484 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
+++ K + G +LNISS AL ++ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 53.2 bits (122), Expect = 9e-07
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V+ITGA +GIG+ R + RG + ++A DV + A E ++TK + V K
Sbjct: 39 GKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTK--NSQVLVRK 96
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIE 492
D++D + + E+ L ++INNA +M Y + ++ G
Sbjct: 97 LDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTY 156
Query: 493 IMGKQ-NGGKGGTVLNISSVA 552
++ +Q V+N+SSVA
Sbjct: 157 LLLEQLKVSAPARVVNVSSVA 177
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 53.2 bits (122), Expect = 9e-07
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G SVK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTG-RSVKIIQA 105
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 483
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 484 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
+++ K + G +LNISS AL ++ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 53.2 bits (122), Expect = 9e-07
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G SVK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTG-RSVKIIQA 105
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 483
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 484 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
+++ K + G +LNISS AL ++ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 53.2 bits (122), Expect = 9e-07
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 2/141 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
GK+V+ITGA +GIG+ R + RG + ++A DV + A E ++TK + V K
Sbjct: 39 GKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTK--NSQVLVRK 96
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 489
D++D + + E+ L ++INNA +M Y + ++ G L
Sbjct: 97 LDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTY 156
Query: 490 EIMGKQNGGKGGTVLNISSVA 552
++ + V+N+SSVA
Sbjct: 157 LLLERLKVSAPARVVNVSSVA 177
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 53.2 bits (122), Expect = 9e-07
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + G HV + + + ++ + T G SV C
Sbjct: 15 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 70
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI-------MNDSYKSYKKQIDINVTALVTG 474
V E L G +D++++NAA+ M+ + + + K +DINV A
Sbjct: 71 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 130
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 131 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 185
Query: 655 GVRVLSICFGATDT 696
+RV + G T
Sbjct: 186 NIRVNCLAPGLIKT 199
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 52.8 bits (121), Expect = 1e-06
Identities = 50/193 (25%), Positives = 91/193 (47%), Gaps = 13/193 (6%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ ++TG+ GIG+ + + G+K V ++ ++D + +E+ K+ + +
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMK-VVLISRSKDKLDQVSSEIKEKFKVET-RTIAV 107
Query: 316 DVTDEELFLELFDTVKNEQGYLDV--VINNAAIMNDSYKSY-----------KKQIDINV 456
D E+++ D +K L++ ++NN M+ Y Y KK I+IN+
Sbjct: 108 DFASEDIY----DKIKTGLAGLEIGILVNNVG-MSYEYPEYFLDVPDLDNVIKKMININI 162
Query: 457 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
++ T + M +++ G +LNISS + + + IY TK+ V FS C L
Sbjct: 163 LSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDFFSQC--LH 217
Query: 637 EHYAKSGVRVLSI 675
E Y GV V S+
Sbjct: 218 EEYRSKGVFVQSV 230
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 52.8 bits (121), Expect = 1e-06
Identities = 50/193 (25%), Positives = 91/193 (47%), Gaps = 13/193 (6%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ ++TG+ GIG+ + + G+K V ++ ++D + +E+ K+ + +
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMK-VVLISRSKDKLDQVSSEIKEKFKVET-RTIAV 107
Query: 316 DVTDEELFLELFDTVKNEQGYLDV--VINNAAIMNDSYKSY-----------KKQIDINV 456
D E+++ D +K L++ ++NN M+ Y Y KK I+IN+
Sbjct: 108 DFASEDIY----DKIKTGLAGLEIGILVNNVG-MSYEYPEYFLDVPDLDNVIKKMININI 162
Query: 457 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
++ T + M +++ G +LNISS + + + IY TK+ V FS C L
Sbjct: 163 LSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDFFSQC--LH 217
Query: 637 EHYAKSGVRVLSI 675
E Y GV V S+
Sbjct: 218 EEYRSKGVFVQSV 230
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/174 (27%), Positives = 82/174 (47%), Gaps = 8/174 (4%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-SVKFYKC 315
K+ L+T + GIG + R + + HV + + + ++ + T G SV C
Sbjct: 31 KVALVTASTDGIGFAIARRLAQDRA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 86
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI-------MNDSYKSYKKQIDINVTALVTG 474
V E L G +D++++NAA+ M+ + + + K +DINV A
Sbjct: 87 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 146
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
T + M K+ GG+V+ +SS+AA S F Y +K+A+L +N + +E
Sbjct: 147 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIE 197
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 51.2 bits (117), Expect = 3e-06
Identities = 29/93 (31%), Positives = 51/93 (54%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNAA 405
+CDV D ++ + G+ ++VINNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 72
Score = 50.8 bits (116), Expect = 5e-06
Identities = 24/66 (36%), Positives = 39/66 (59%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 316 DVTDEE 333
DV D++
Sbjct: 64 DVADQQ 69
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAA 555
N+ MG+ GG+ G ++N +SVAA
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAA 555
N+ MG+ GG+ G ++N +SVAA
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Frame = +1
Query: 127 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKF 306
S KG + +ITG ASG+G ++ +G V +LD+ G A +L N+ F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLG-----NNCVF 60
Query: 307 YKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 450
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 451 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAA 555
N+ MG+ GG+ G ++N +SVAA
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 48.8 bits (111), Expect = 2e-05
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNSVKFY 309
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 108
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 471
D+TD V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
T + M ++ GK ++ ++S+ + + Y +K A+ F N GL A
Sbjct: 169 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 223
Query: 652 -SGVRVLSICFG 684
G+ V +IC G
Sbjct: 224 YPGIIVSNICPG 235
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 48.8 bits (111), Expect = 2e-05
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNSVKFY 309
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 108
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 471
D+TD V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
T + M ++ GK ++ ++S+ + + Y +K A+ F N GL A
Sbjct: 169 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 223
Query: 652 -SGVRVLSICFG 684
G+ V +IC G
Sbjct: 224 YPGIIVSNICPG 235
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 48.8 bits (111), Expect = 2e-05
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNSVKFY 309
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 58
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 471
D+TD V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 59 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 118
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
T + M ++ GK ++ ++S+ + + Y +K A+ F N GL A
Sbjct: 119 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 173
Query: 652 -SGVRVLSICFG 684
G+ V +IC G
Sbjct: 174 YPGIIVSNICPG 185
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 48.8 bits (111), Expect = 2e-05
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNSVKFY 309
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 108
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 471
D+TD V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
T + M ++ GK ++ ++S+ + + Y +K A+ F N GL A
Sbjct: 169 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 223
Query: 652 -SGVRVLSICFG 684
G+ V +IC G
Sbjct: 224 YPGIIVSNICPG 235
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 48.8 bits (111), Expect = 2e-05
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 11/192 (5%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNSVKFY 309
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 58
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 471
D+TD V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 59 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 118
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAK 651
T + M ++ GK ++ ++S+ + + Y +K A+ F N GL A
Sbjct: 119 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 173
Query: 652 -SGVRVLSICFG 684
G+ V +IC G
Sbjct: 174 YPGIIVSNICPG 185
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 46.0 bits (104), Expect = 1e-04
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 7/198 (3%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVK 303
E +GK V++TGA+ GIG + + + G HV + ++++ + + + + G S
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHC-LELGAASA- 86
Query: 304 FYKCDVTDEELFLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVTA 462
Y ++ F E F + G LD++I N + +D +K +++N +
Sbjct: 87 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLS 146
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
V T+ A+ ++ + N G+++ +SS+A M Y +K A+ F + I E
Sbjct: 147 YVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYS 202
Query: 643 YAKSGVRVLSICFGATDT 696
++ V + G DT
Sbjct: 203 VSRVNVSITLCVLGLIDT 220
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 46.0 bits (104), Expect = 1e-04
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 7/198 (3%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVK 303
E +GK V++TGA+ GIG + + + G HV + ++++ + + + + G S
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHC-LELGAASA- 86
Query: 304 FYKCDVTDEELFLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVTA 462
Y ++ F E F + G LD++I N + +D +K +++N +
Sbjct: 87 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLS 146
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
V T+ A+ ++ + N G+++ +SS+A M Y +K A+ F + I E
Sbjct: 147 YVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYS 202
Query: 643 YAKSGVRVLSICFGATDT 696
++ V + G DT
Sbjct: 203 VSRVNVSITLCVLGLIDT 220
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 46.0 bits (104), Expect = 1e-04
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 7/198 (3%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVK 303
E +GK V++TGA+ GIG + + + G HV + ++++ + + + + G S
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHC-LELGAASA- 86
Query: 304 FYKCDVTDEELFLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVTA 462
Y ++ F E F + G LD++I N + +D +K +++N +
Sbjct: 87 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLS 146
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
V T+ A+ ++ + N G+++ +SS+A M Y +K A+ F + I E
Sbjct: 147 YVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYS 202
Query: 643 YAKSGVRVLSICFGATDT 696
++ V + G DT
Sbjct: 203 VSRVNVSITLCVLGLIDT 220
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 46.0 bits (104), Expect = 1e-04
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 7/198 (3%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVK 303
E +GK V++TGA+ GIG + + + G HV + ++++ + + + + G S
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHC-LELGAASA- 86
Query: 304 FYKCDVTDEELFLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVTA 462
Y ++ F E F + G LD++I N + +D +K +++N +
Sbjct: 87 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLS 146
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
V T+ A+ ++ + N G+++ +SS+A M Y +K A+ F + I E
Sbjct: 147 YVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYS 202
Query: 643 YAKSGVRVLSICFGATDT 696
++ V + G DT
Sbjct: 203 VSRVNVSITLCVLGLIDT 220
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 46.0 bits (104), Expect = 1e-04
Identities = 46/198 (23%), Positives = 90/198 (45%), Gaps = 7/198 (3%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVK 303
E +GK V++TGA+ GIG + + + G HV + ++++ + + + + G S
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHC-LELGAASA- 86
Query: 304 FYKCDVTDEELFLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVTA 462
Y ++ F E F + G LD++I N + +D +K +++N +
Sbjct: 87 HYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLS 146
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
V T+ A+ ++ + N G+++ +SS+A M Y +K A+ F + I E
Sbjct: 147 YVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYS 202
Query: 643 YAKSGVRVLSICFGATDT 696
++ V + G DT
Sbjct: 203 VSRVNVSITLCVLGLIDT 220
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 453
+ DVTD E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 454 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 45.2 bits (102), Expect = 2e-04
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 9/189 (4%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNSVK 303
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 465
D+TD + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 466 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 171 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 646 AKSGVRVLS 672
+ V V+S
Sbjct: 228 YEIEVTVIS 236
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 45.2 bits (102), Expect = 2e-04
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 9/189 (4%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNSVK 303
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 465
D+TD + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 466 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 171 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 646 AKSGVRVLS 672
+ V V+S
Sbjct: 228 YEIEVTVIS 236
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 45.2 bits (102), Expect = 2e-04
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 9/189 (4%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNSVK 303
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 465
D+TD + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 466 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 171 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 646 AKSGVRVLS 672
+ V V+S
Sbjct: 228 YEIEVTVIS 236
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 45.2 bits (102), Expect = 2e-04
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 9/189 (4%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNSVK 303
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 36 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 95
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 465
D+TD + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 96 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 155
Query: 466 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 156 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 212
Query: 646 AKSGVRVLS 672
+ V V+S
Sbjct: 213 YEIEVTVIS 221
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 45.2 bits (102), Expect = 2e-04
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 9/189 (4%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNSVK 303
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 56 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 115
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 465
D+TD + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 116 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 175
Query: 466 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHY 645
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 176 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 232
Query: 646 AKSGVRVLS 672
+ V V+S
Sbjct: 233 YEIEVTVIS 241
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 145 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
VLITG GIG + R ERG + + + E + E+ + G ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMG-TECHYFICDVG 98
Query: 325 DEELFLELFDTVKNEQGYLDVVINNAAIMN 414
+ E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 145 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
VLITG GIG + R ERG + + + E + E+ + G ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMG-TECHYFICDVG 98
Query: 325 DEELFLELFDTVKNEQGYLDVVINNAAIMN 414
+ E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 145 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
VLITG GIG + R ERG + + + E + E+ + G ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMG-TECHYFICDVG 98
Query: 325 DEELFLELFDTVKNEQGYLDVVINNAAIMN 414
+ E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 145 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
VLITG GIG + R ERG + + + E + E+ + G ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMG-TECHYFICDVG 98
Query: 325 DEELFLELFDTVKNEQGYLDVVINNAAIMN 414
+ E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 145 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
VLITG GIG + R ERG + + + E + E+ + G ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMG-TECHYFICDVG 98
Query: 325 DEELFLELFDTVKNEQGYLDVVINNAAIMN 414
+ E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 145 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
VLITG GIG + R ERG + + + E + E+ + G ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMG-TECHYFICDVG 98
Query: 325 DEELFLELFDTVKNEQGYLDVVINNAAIMN 414
+ E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G++ ++TGA+ GIG G+ + + G V I D+ R + E + G V C
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 316 DVTDEELFLELFDTV-KNEQGYLDVVINNA 402
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G++ ++TGA+ GIG G+ + + G V I D+ R + E + G V C
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 316 DVTDEELFLELFDTV-KNEQGYLDVVINNA 402
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G++ ++TGA+ GIG G+ + + G V I D+ R + E + G V C
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 316 DVTDEELFLELFDTV-KNEQGYLDVVINNA 402
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 43.6 bits (98), Expect = 7e-04
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIAARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 6 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 58
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 59 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 112
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 113 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 165
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NADPH)
3, EC 1.1.1.284. protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ VL+TGA GIG G V+ + G + VA+ D L++ + G V
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQAD----LDSLVRECPGIEPV---CV 59
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 477
D+ D E +V G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 60 DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ L+TGA GIG + R + + V + G+A +L + S +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE--GLSPRFHQLD 63
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAI 408
+ D + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 42.7 bits (96), Expect = 0.001
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 5/159 (3%)
Frame = +1
Query: 103 YVEHCVMESWKGKIVLITGAASGIGEGVVRLILER-GVKHVAILDVAEDSGRALENELNT 279
+V H + G++ L+TG SGIG+ I +R G H+ D A E+
Sbjct: 24 FVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQA--PAEDARGEIIR 81
Query: 280 KYGPNSVKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVT 459
+ G ++ + D++D + + + K E L V+INNA M + + + ++ N
Sbjct: 82 ESGNQNIFLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFA 140
Query: 460 ALVTG----TLKAIEIMGKQNGGKGGTVLNISSVAALCQ 564
A G T I ++ K++ + V+ +SS L Q
Sbjct: 141 ANTLGVYILTTGLIPVLEKEHDPR---VITVSSGGMLVQ 176
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 319 VTDEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 468
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYA 648
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 649 KSGVRVLSI 675
K G++V SI
Sbjct: 252 KWGIKVASI 260
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 319 VTDEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 468
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYA 648
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 649 KSGVRVLSI 675
K G++V SI
Sbjct: 252 KWGIKVASI 260
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 319 VTDEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 468
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYA 648
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 649 KSGVRVLSI 675
K G++V SI
Sbjct: 252 KWGIKVASI 260
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 319 VTDEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 468
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYA 648
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 649 KSGVRVLSI 675
K G++V SI
Sbjct: 252 KWGIKVASI 260
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS---VK 303
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 477
+C++ +EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 478 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHMFPIYFG-TKSAVLQFSNCIGLEEHYAK 651
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 652 SGVRVLSICFG 684
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 319 VTDEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 468
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYA 648
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 649 KSGVRVLSI 675
K G++V SI
Sbjct: 252 KWGIKVASI 260
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 319 VTDEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 468
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 469 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYA 648
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 649 KSGVRVLSI 675
K G++V SI
Sbjct: 252 KWGIKVASI 260
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS---VK 303
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 477
+C++ +EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 478 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHMFPIYFG-TKSAVLQFSNCIGLEEHYAK 651
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 652 SGVRVLSICFG 684
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS---VK 303
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 36 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 94
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 477
+C++ +EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 95 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 154
Query: 478 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHMFPIYFG-TKSAVLQFSNCIGLEEHYAK 651
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 155 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 210
Query: 652 SGVRVLSICFG 684
SG+R+ + G
Sbjct: 211 SGIRINCVAPG 221
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS---VK 303
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 477
+C++ +EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 478 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHMFPIYFG-TKSAVLQFSNCIGLEEHYAK 651
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 652 SGVRVLSICFG 684
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/89 (30%), Positives = 44/89 (49%)
Frame = +1
Query: 142 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDV 321
+ L+TG GIG +VR + V + G+A +L + S +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE--GLSPRFHQLDI 64
Query: 322 TDEELFLELFDTVKNEQGYLDVVINNAAI 408
D + L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 9/194 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNS 297
+S G+IVLITGA GIG R K +IL + + + R +E K G +
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV-T 86
Query: 298 VKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 459
Y D ++ E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 460 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE- 636
T + M ++N G TV ++ + ++ P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 637 EHYAKSGVRVLSIC 678
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 9/194 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNS 297
+S G+IVLITGA GIG R K +IL + + + R +E K G +
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV-T 86
Query: 298 VKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 459
Y D ++ E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 460 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE- 636
T + M ++N G TV ++ + ++ P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 637 EHYAKSGVRVLSIC 678
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 41.9 bits (94), Expect = 0.002
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ ++TGA+ GIG G+ + + G V I D+ R + E + G V C
Sbjct: 7 GQACVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 316 DVTDEELFLELFDTV-KNEQGYLDVVINNA 402
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 9/194 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNS 297
+S G+IVLITGA GIG R K +IL + + + R +E K G +
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV-T 86
Query: 298 VKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 459
Y D ++ E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 460 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE- 636
T + M ++N G TV ++ + ++ P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 637 EHYAKSGVRVLSIC 678
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 9/194 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNS 297
+S G+IVLITGA GIG R K +IL + + + R +E K G +
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV-T 86
Query: 298 VKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 459
Y D ++ E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 460 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE- 636
T + M ++N G TV ++ + ++ P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 637 EHYAKSGVRVLSIC 678
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 9/194 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNS 297
+S G+IVLITGA GIG R K +IL + + + R +E K G +
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV-T 86
Query: 298 VKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 459
Y D ++ E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 460 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE- 636
T + M ++N G TV ++ + ++ P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 637 EHYAKSGVRVLSIC 678
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 9/194 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNS 297
+S G+IVLITGA GIG R K +IL + + + R +E K G +
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGV-T 86
Query: 298 VKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 459
Y D ++ E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 460 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE- 636
T + M ++N G TV ++ + ++ P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 637 EHYAKSGVRVLSIC 678
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE KY ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KY--PGIQTRVL 57
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVIN------NAAIMNDSYKSYKKQIDINVTALVTGT 477
DVT + + D NE LDV+ N + +++ K + +++NV ++
Sbjct: 58 DVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL-M 112
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAA 555
+KA + K K G ++N+SSVA+
Sbjct: 113 IKA--FLPKMLAQKSGNIINMSSVAS 136
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/96 (27%), Positives = 46/96 (47%)
Frame = +1
Query: 121 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV 300
M + +G+ ++TGA SGIG+ + RG + V + +++ G A +L + G N V
Sbjct: 31 MGNLRGRTAVVTGANSGIGKMTALELARRGAR-VVLACRSQERGEAAAFDLRQESGNNEV 89
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAI 408
F D+ + + LD++I+NA I
Sbjct: 90 IFMALDLASLASVRAFATAFLSSEPRLDILIHNAGI 125
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE KY ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KY--PGIQTRVL 57
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVIN------NAAIMNDSYKSYKKQIDINVTALVTGT 477
DVT + + D NE LDV+ N + +++ K + +++NV ++
Sbjct: 58 DVTKK----KQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL-M 112
Query: 478 LKAIEIMGKQNGGKGGTVLNISSVAA 555
+KA + K K G ++N+SSVA+
Sbjct: 113 IKA--FLPKMLAQKSGNIINMSSVAS 136
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 40.7 bits (91), Expect = 0.005
Identities = 34/140 (24%), Positives = 65/140 (46%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK++++T AA GIG+ G K +A D+ E + LE + V K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRVLDVT-KKK 63
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 495
+ +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFASEVERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA--F 116
Query: 496 MGKQNGGKGGTVLNISSVAA 555
+ K K G ++N+SSVA+
Sbjct: 117 LPKMLAQKSGNIINMSSVAS 136
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 40.3 bits (90), Expect = 0.006
Identities = 56/208 (26%), Positives = 87/208 (41%), Gaps = 16/208 (7%)
Frame = +1
Query: 121 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 291
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 292 NSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 447
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 448 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQ 612
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 613 FSNCIGLEEHYAKSGVRVLSICFGATDT 696
+ LEE VRVL+ G DT
Sbjct: 180 LFQVLALEE----PNVRVLNYAPGPLDT 203
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 40.3 bits (90), Expect = 0.006
Identities = 56/208 (26%), Positives = 87/208 (41%), Gaps = 16/208 (7%)
Frame = +1
Query: 121 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 291
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 292 NSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 447
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 448 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQ 612
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 613 FSNCIGLEEHYAKSGVRVLSICFGATDT 696
+ LEE VRVL+ G DT
Sbjct: 180 LFQVLALEE----PNVRVLNYAPGPLDT 203
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 40.3 bits (90), Expect = 0.006
Identities = 56/208 (26%), Positives = 87/208 (41%), Gaps = 16/208 (7%)
Frame = +1
Query: 121 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 291
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVRLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 292 NSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 447
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 448 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQ 612
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 613 FSNCIGLEEHYAKSGVRVLSICFGATDT 696
+ LEE VRVL+ G DT
Sbjct: 180 LFQVLALEE----PNVRVLNYAPGPLDT 203
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 39.9 bits (89), Expect = 0.008
Identities = 40/191 (20%), Positives = 86/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS---VK 303
+G++ +TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAFVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 304 FYKCDVTDEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 477
+C++ +EE L + + G ++ ++NN ++ + K + +TG+
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGS 135
Query: 478 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHMFPIYFG-TKSAVLQFSNCIGLEEHYAK 651
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 652 SGVRVLSICFG 684
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 39.5 bits (88), Expect = 0.011
Identities = 25/78 (32%), Positives = 44/78 (56%)
Frame = +1
Query: 403 AIMNDSYKSYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPI 582
++M+ + + + K +DINV A T + M K+ GG+V+ +SS+AA S F
Sbjct: 1 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSP 57
Query: 583 YFGTKSAVLQFSNCIGLE 636
Y +K+A+L +N + +E
Sbjct: 58 YNVSKTALLGLNNTLAIE 75
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 39.5 bits (88), Expect = 0.011
Identities = 43/175 (24%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN--SVKFYK 312
K VL+TG SG G + + + +G A + +D G EL++ +V+
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 313 CDVTDEELFLELF-DTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 471
C + E +E+ ++K+ + + ++NNA I S ++YK+ ++N+ V
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
T + ++ + G V+NISS+ + Y TK V FS+C+ E
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 39.5 bits (88), Expect = 0.011
Identities = 43/175 (24%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN--SVKFYK 312
K VL+TG SG G + + + +G A + +D G EL++ +V+
Sbjct: 56 KAVLVTGCDSGFGFALAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 313 CDVTDEELFLELF-DTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 471
C + E +E+ ++K+ + + ++NNA I S ++YK+ ++N+ V
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
T + ++ + G V+NISS+ + Y TK V FS+C+ E
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 39.5 bits (88), Expect = 0.011
Identities = 43/175 (24%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN--SVKFYK 312
K VL+TG SG G + + + +G A + +D G EL++ +V+
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 313 CDVTDEELFLELF-DTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 471
C + E +E+ ++K+ + + ++NNA I S ++YK+ ++N+ V
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
T + ++ + G V+NISS+ + Y TK V FS+C+ E
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 39.5 bits (88), Expect = 0.011
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +1
Query: 433 KKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQ 612
KK I+IN+ ++ T + M +++ G +LNISS + + + IY TK+ V
Sbjct: 20 KKMININILSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDF 76
Query: 613 FSNCIGLEEHYAKSGVRVLSI 675
FS C L E Y GV V S+
Sbjct: 77 FSQC--LHEEYRSKGVFVQSV 95
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 179
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 180 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 210
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 179
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 180 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 210
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCD 318
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 319 VTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 38.3 bits (85), Expect = 0.026
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+IVLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E K E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 37.9 bits (84), Expect = 0.034
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 8/193 (4%)
Frame = +1
Query: 124 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNS-V 300
+S G+ VLITGA GIG RL K + L + + + LE G + V
Sbjct: 32 KSVTGETVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 301 KFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 462
+ D ++ E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 463 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 643 YAK-SGVRVLSIC 678
+ +GV+ +C
Sbjct: 205 ALQITGVKTTCLC 217
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 37.9 bits (84), Expect = 0.034
Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 10/204 (4%)
Frame = +1
Query: 94 MHLYVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENEL 273
+H Y E V+ + K V ITG SG G+ + R + RG++ +A + E L +
Sbjct: 15 LHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC-LTEKGAEQLRGQT 73
Query: 274 NTKYGPNSVKFYKCDVTDEELFLELFDTVK---NEQGYLDVVINNAAIM-----ND--SY 423
+ + ++ DVT E VK ++G L ++NNA I N+ +
Sbjct: 74 SDR-----LETVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTK 127
Query: 424 KSYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSA 603
+ + +D+N+ ++ TL + ++ K G V+N+SSV S Y +K
Sbjct: 128 QDFVTILDVNLLGVIDVTLSLLPLVRKAR----GRVVNVSSVMGRV-SLFGGGYCISKYG 182
Query: 604 VLQFSNCIGLEEHYAKSGVRVLSI 675
V FS+ + E Y GV+V I
Sbjct: 183 VEAFSDSLRRELSY--FGVKVAMI 204
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 37.5 bits (83), Expect = 0.045
Identities = 36/187 (19%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 239
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 240 GIFVQSL 246
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 37.5 bits (83), Expect = 0.045
Identities = 36/187 (19%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 239
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 240 GIFVQSL 246
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 37.5 bits (83), Expect = 0.045
Identities = 36/187 (19%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 104
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 105 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 161
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 162 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 218
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 219 GIFVQSL 225
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 37.5 bits (83), Expect = 0.045
Identities = 36/187 (19%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 239
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 240 GIFVQSL 246
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 37.5 bits (83), Expect = 0.045
Identities = 36/187 (19%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 104
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 105 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 161
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 162 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 218
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 219 GIFVQSL 225
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 37.1 bits (82), Expect = 0.060
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNT--------KYGP 291
G++VL+TGA +G+G ERG V + D+ D + L + G
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGG 67
Query: 292 NSVKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------- 447
+V Y V + E ++ T + G +DVV+NNA I+ D +S+ + D
Sbjct: 68 KAVANYD-SVEEGE---KVVKTALDAFGRIDVVVNNAGILRD--RSFARISDEDWDIIHR 121
Query: 448 INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCI 627
+++ T A E M KQ K G ++ SS + + + Y K +L +N +
Sbjct: 122 VHLRGSFQVTRAAWEHMKKQ---KYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
Query: 628 GLE 636
+E
Sbjct: 179 AIE 181
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 37.1 bits (82), Expect = 0.060
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNT--------KYGP 291
G++VL+TGA +G+G ERG V + D+ D + L + G
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGG 67
Query: 292 NSVKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------- 447
+V Y V + E ++ T + G +DVV+NNA I+ D +S+ + D
Sbjct: 68 KAVANYD-SVEEGE---KVVKTALDAFGRIDVVVNNAGILRD--RSFARISDEDWDIIHR 121
Query: 448 INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCI 627
+++ T A E M KQ K G ++ SS + + + Y K +L +N +
Sbjct: 122 VHLRGSFQVTRAAWEHMKKQ---KYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
Query: 628 GLE 636
+E
Sbjct: 179 AIE 181
>AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 223
Score = 37.1 bits (82), Expect = 0.060
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + F +K LD + NA IM
Sbjct: 63 DVSNLQSFFRASKELKQRFQRLDRIYLNAGIM 94
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 37.1 bits (82), Expect = 0.060
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNT--------KYGP 291
G++VL+TGA +G+G ERG V + D+ D + L + G
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGG 67
Query: 292 NSVKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------- 447
+V Y V + E ++ T + G +DVV+NNA I+ D +S+ + D
Sbjct: 68 KAVANYD-SVEEGE---KVVKTALDAFGRIDVVVNNAGILRD--RSFARISDEDWDIIHR 121
Query: 448 INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCI 627
+++ T A E M KQ K G ++ SS + + + Y K +L +N +
Sbjct: 122 VHLRGSFQVTRAAWEHMKKQ---KYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
Query: 628 GLE 636
+E
Sbjct: 179 AIE 181
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 36.3 bits (80), Expect = 0.10
Identities = 41/175 (23%), Positives = 77/175 (44%), Gaps = 9/175 (5%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVVRLILERGVKHVA---ILDVAEDSGRALENELNTKYGPNSVKFY 309
K VL+TG SG G + + + +G A + D D + L++ + + + +
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVF 115
Query: 310 KCDVTDEELFLELFDTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 471
+ + ++ + F+ E+G +V NNA I S ++YK+ ++N+ V
Sbjct: 116 RSEEVEKVVGDCPFEPEGPEKGMWGLV-NNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 472 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLE 636
T + ++ + G V+NISS+ + Y TK V FS+C+ E
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 36.3 bits (80), Expect = 0.10
Identities = 35/187 (18%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +++ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSR--ALQYEYASK 239
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 240 GIFVQSL 246
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 36.3 bits (80), Expect = 0.10
Identities = 35/187 (18%), Positives = 81/187 (43%), Gaps = 7/187 (3%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y +
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 474
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 475 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEHYAKS 654
+ + + G K G ++ ISS + + + +++ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSR--ALQYEYASK 239
Query: 655 GVRVLSI 675
G+ V S+
Sbjct: 240 GIFVQSL 246
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 36.3 bits (80), Expect = 0.10
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 16/189 (8%)
Frame = +1
Query: 121 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 291
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 292 NSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 447
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 448 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQ 612
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 613 FSNCIGLEE 639
+ LEE
Sbjct: 180 LFQVLALEE 188
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 36.3 bits (80), Expect = 0.10
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 16/189 (8%)
Frame = +1
Query: 121 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 291
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 292 NSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 447
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 448 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQ 612
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 613 FSNCIGLEE 639
+ LEE
Sbjct: 180 LFQVLALEE 188
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 35.9 bits (79), Expect = 0.14
Identities = 53/205 (25%), Positives = 98/205 (47%), Gaps = 11/205 (5%)
Frame = +1
Query: 94 MHLYVEHC-VMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENE 270
M+ + ++C ++ + K V ITG SG G + + +++RG++ +A E+ + L+ +
Sbjct: 10 MYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRD 68
Query: 271 LNTKYGPNSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVVINNAAI-----MND--S 420
T Y ++ DVT E V++ EQG L ++NNA + N+ +
Sbjct: 69 --TSY---RLQTTLLDVTKSESIKAAAQWVRDKVGEQG-LWALVNNAGVGLPSGPNEWLT 122
Query: 421 YKSYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKS 600
+ K I++N+ L+ TL + ++ + G V+N+SS + + Y +K
Sbjct: 123 KDDFVKVINVNLVGLIEVTLHMLPMVKRAR----GRVVNMSSSGGRV-AVIGGGYCVSKF 177
Query: 601 AVLQFSNCIGLEEHYAKSGVRVLSI 675
V FS+ I E +Y GV+V I
Sbjct: 178 GVEAFSDSIRRELYY--FGVKVCII 200
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 35.9 bits (79), Expect = 0.14
Identities = 53/205 (25%), Positives = 98/205 (47%), Gaps = 11/205 (5%)
Frame = +1
Query: 94 MHLYVEHC-VMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENE 270
M+ + ++C ++ + K V ITG SG G + + +++RG++ +A E+ + L+ +
Sbjct: 10 MYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRD 68
Query: 271 LNTKYGPNSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVVINNAAI-----MND--S 420
T Y ++ DVT E V++ EQG L ++NNA + N+ +
Sbjct: 69 --TSY---RLQTTLLDVTKSESIKAAAQWVRDKVGEQG-LWALVNNAGVGLPSGPNEWLT 122
Query: 421 YKSYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKS 600
+ K I++N+ L+ TL + ++ + G V+N+SS + + Y +K
Sbjct: 123 KDDFVKVINVNLVGLIEVTLHMLPMVKRAR----GRVVNMSSSGGRV-AVIGGGYCVSKF 177
Query: 601 AVLQFSNCIGLEEHYAKSGVRVLSI 675
V FS+ I E +Y GV+V I
Sbjct: 178 GVEAFSDSIRRELYY--FGVKVCII 200
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 35.9 bits (79), Expect = 0.14
Identities = 53/205 (25%), Positives = 98/205 (47%), Gaps = 11/205 (5%)
Frame = +1
Query: 94 MHLYVEHC-VMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENE 270
M+ + ++C ++ + K V ITG SG G + + +++RG++ +A E+ + L+ +
Sbjct: 10 MYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRD 68
Query: 271 LNTKYGPNSVKFYKCDVTDEELFLELFDTVKN---EQGYLDVVINNAAI-----MND--S 420
T Y ++ DVT E V++ EQG L ++NNA + N+ +
Sbjct: 69 --TSY---RLQTTLLDVTKSESIKAAAQWVRDKVGEQG-LWALVNNAGVGLPSGPNEWLT 122
Query: 421 YKSYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKS 600
+ K I++N+ L+ TL + ++ + G V+N+SS + + Y +K
Sbjct: 123 KDDFVKVINVNLVGLIEVTLHMLPMVKRAR----GRVVNMSSSGGRV-AVIGGGYCVSKF 177
Query: 601 AVLQFSNCIGLEEHYAKSGVRVLSI 675
V FS+ I E +Y GV+V I
Sbjct: 178 GVEAFSDSIRRELYY--FGVKVCII 200
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.14
Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 69 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL 128
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSNCIGLEEH 642
GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE-- 186
Query: 643 YAKSGVRVLSICFG 684
+ G+R S+ G
Sbjct: 187 LGRHGIRCNSVLPG 200
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 35.5 bits (78), Expect = 0.18
Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV--KFY 309
G V ITGA+ GIG+ + + G V A+ + L +V K
Sbjct: 10 GCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKAL 69
Query: 310 KC--DVTDEELFLELFDTVKNEQGYLDVVINNAAI--MNDSYKSYKKQIDINVTALVTGT 477
C DV DE+ + + G +D+++NNA+ + ++ + K++D+ + GT
Sbjct: 70 PCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGT 129
Query: 478 -LKAIEIMGKQNGGKGGTVLNIS 543
L + + K +LNIS
Sbjct: 130 YLASKACIPYLKKSKVAHILNIS 152
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 35.5 bits (78), Expect = 0.18
Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV--KFY 309
G V ITGA+ GIG+ + + G V A+ + L +V K
Sbjct: 10 GCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKAL 69
Query: 310 KC--DVTDEELFLELFDTVKNEQGYLDVVINNAAI--MNDSYKSYKKQIDINVTALVTGT 477
C DV DE+ + + G +D+++NNA+ + ++ + K++D+ + GT
Sbjct: 70 PCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGT 129
Query: 478 -LKAIEIMGKQNGGKGGTVLNIS 543
L + + K +LNIS
Sbjct: 130 YLASKACIPYLKKSKVAHILNIS 152
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 35.5 bits (78), Expect = 0.18
Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSV--KFY 309
G V ITGA+ GIG+ + + G V A+ + L +V K
Sbjct: 10 GCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKAL 69
Query: 310 KC--DVTDEELFLELFDTVKNEQGYLDVVINNAAI--MNDSYKSYKKQIDINVTALVTGT 477
C DV DE+ + + G +D+++NNA+ + ++ + K++D+ + GT
Sbjct: 70 PCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGT 129
Query: 478 -LKAIEIMGKQNGGKGGTVLNIS 543
L + + K +LNIS
Sbjct: 130 YLASKACIPYLKKSKVAHILNIS 152
>BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 35.1 bits (77), Expect = 0.24
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 9/161 (5%)
Frame = +1
Query: 94 MHLYVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENEL 273
+H Y E V+ + K V ITG SG G + R + RG++ +A + E L +
Sbjct: 15 LHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQT 73
Query: 274 NTKYGPNSVKFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYK 426
+ + ++ DVT E VK G + ++NNA I+ + +
Sbjct: 74 SDR-----LETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTE 128
Query: 427 SYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ +N+ ++ TL + ++ + G ++N+SS+
Sbjct: 129 DSMNMLKVNLIGVIQVTLSMLPLVRRAR----GRIVNVSSI 165
>BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 35.1 bits (77), Expect = 0.24
Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 15/154 (9%)
Frame = +1
Query: 280 KYGPNSVKFYKCDVTDEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY---------- 423
K G N V F DVT E+ K + G +DV +N A A+ + +Y
Sbjct: 3 KLGNNCV-FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTL 61
Query: 424 KSYKKQIDINVTALVTGTLKAIEIMGKQN---GGKGGTVLNISSVAALCQSHMFPIYFGT 594
+ +++ +D+N+ MG+ GG+ G ++N +SVAA Y +
Sbjct: 62 EDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS 121
Query: 595 KSAVLQFSNCIGLEEHYAKSGVRVLSICFGATDT 696
K ++ + + + A G+RV++I G T
Sbjct: 122 KGGIVGMT--LPIARDLAPIGIRVMTIAPGLFGT 153
>AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 111
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens
cDNA FLJ12867 fis, clone NT2RP2003702, highly similar to
Homo sapiens 17 beta-hydroxysteroid dehydrogenase type
VII ).
Length = 155
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 35.1 bits (77), Expect = 0.24
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 9/161 (5%)
Frame = +1
Query: 94 MHLYVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENEL 273
+H Y E V+ + K V ITG SG G + R + RG++ +A + E L +
Sbjct: 15 LHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQT 73
Query: 274 NTKYGPNSVKFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYK 426
+ + ++ DVT E VK G + ++NNA I+ + +
Sbjct: 74 SDR-----LETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTE 128
Query: 427 SYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ +N+ ++ TL + ++ + G ++N+SS+
Sbjct: 129 DSMNMLKVNLIGVIQVTLSMLPLVRRAR----GRIVNVSSI 165
>AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protein
protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.24
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 35.1 bits (77), Expect = 0.24
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 9/161 (5%)
Frame = +1
Query: 94 MHLYVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENEL 273
+H Y E V+ + K V ITG SG G + R + RG++ +A + E L +
Sbjct: 15 LHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQT 73
Query: 274 NTKYGPNSVKFYKCDVTDEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYK 426
+ + ++ DVT E VK G + ++NNA I+ + +
Sbjct: 74 SDR-----LETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTE 128
Query: 427 SYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 549
+ +N+ ++ TL + ++ + G ++N+SS+
Sbjct: 129 DSMNMLKVNLIGVIQVTLSMLPLVRRAR----GRIVNVSSI 165
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.32
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +1
Query: 142 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYK 312
+VLITG +SGIG VRL + + K A L + GR E P S++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 313 CDVTDEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 486
DV D + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 487 IEIMGKQNGGKG-GTVLNISSVAALCQSHMFPIYFGTKSAV 606
++ +G G VL SV L +Y +K A+
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 34.3 bits (75), Expect = 0.42
Identities = 27/85 (31%), Positives = 42/85 (49%)
Frame = +1
Query: 442 IDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVLQFSN 621
+DINV A T + M K+ GG+V+ +SS+AA S F Y +K+A+L +
Sbjct: 104 LDINVKAPALMTKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTK 160
Query: 622 CIGLEEHYAKSGVRVLSICFGATDT 696
+ +E A +RV + G T
Sbjct: 161 TLAIE--LAPRNIRVNCLAPGLIKT 183
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 34.3 bits (75), Expect = 0.42
Identities = 35/108 (32%), Positives = 48/108 (44%), Gaps = 12/108 (11%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNSV 300
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 301 KFYKCDVTDEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 423
++ EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 34.3 bits (75), Expect = 0.42
Identities = 35/108 (32%), Positives = 48/108 (44%), Gaps = 12/108 (11%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNSV 300
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 301 KFYKCDVTDEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 423
++ EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 34.3 bits (75), Expect = 0.42
Identities = 29/140 (20%), Positives = 61/140 (43%), Gaps = 1/140 (0%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK V++TGA +GIG+ + RG ++ + + A ++ + + V
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRG-GNIILACRDMEKCEAAAKDIRGETLNHHVNARHL 96
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAIE 492
D+ + E + E+ +D++INNA +M + + + ++ G L
Sbjct: 97 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 156
Query: 493 IMGKQNGGKGGTVLNISSVA 552
++ K ++N+SS+A
Sbjct: 157 LLDKLKASAPSRIINLSSLA 176
>AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid
dehydrogenase protein.
Length = 341
Score = 34.3 bits (75), Expect = 0.42
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIM 411
DV++ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDRIYLNAGIM 94
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 34.3 bits (75), Expect = 0.42
Identities = 35/108 (32%), Positives = 48/108 (44%), Gaps = 12/108 (11%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNSV 300
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 301 KFYKCDVTDEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 423
++ EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 34.3 bits (75), Expect = 0.42
Identities = 35/108 (32%), Positives = 48/108 (44%), Gaps = 12/108 (11%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNSV 300
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 301 KFYKCDVTDEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 423
++ EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein protein.
Length = 229
Score = 33.9 bits (74), Expect = 0.56
Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGY--LDVVINNAAIM 411
DV++ + F +K + LD + NA IM
Sbjct: 63 DVSNLQSFFRASKELKQSCRFQRLDRIYLNAGIM 96
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 33.9 bits (74), Expect = 0.56
Identities = 28/107 (26%), Positives = 49/107 (45%)
Frame = +1
Query: 136 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
GK+V++TGA +G R+ ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTG-----ARV-------YLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 86
Query: 316 DVTDEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINV 456
D++D + E+ +L V+INNA +M Y ++++
Sbjct: 87 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHI 133
>AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 form 2 protein.
Length = 229
Score = 33.9 bits (74), Expect = 0.56
Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 139 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKC 315
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 316 DVTDEELFLELFDTVKNEQGY--LDVVINNAAIM 411
DV++ + F +K + LD + NA IM
Sbjct: 63 DVSNLQSFFRASKELKQSCRFQRLDRIYLNAGIM 96
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 33.5 bits (73), Expect = 0.74
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 10/169 (5%)
Frame = +1
Query: 133 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP--NS 297
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP +
Sbjct: 8 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 66
Query: 298 VKFYKCDVTDEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTALV 468
++ DV++ L + V+ VV++ A I D + + + D + + +
Sbjct: 67 HAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVNL 126
Query: 469 TGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHMFPIYFGTKSAVL 609
GT + + + G G+++NISS+ + Y +K+ V+
Sbjct: 127 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVI 175
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 33.5 bits (73), Expect = 0.74
Identities = 53/204 (25%), Positives = 89/204 (43%), Gaps = 10/204 (4%)
Frame = +1
Query: 94 MHLYVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENEL 273
+H Y E V+ + K V ITG SG G+ + R + RG++ +A + E L +
Sbjct: 15 LHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC-LTEKGAEQLRGQT 73
Query: 274 NTKYGPNSVKFYKCDVTDEELFLELFDTVK---NEQGYLDVVINNAAIMNDSYKS--YKK 438
+ + ++ DVT E VK ++G L ++NNA I + + K
Sbjct: 74 SDR-----LETVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTK 127
Query: 439 Q-----IDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHMFPIYFGTKSA 603
Q +D+N+ ++ TL + ++ + G V+N+ SV S Y +K
Sbjct: 128 QDLLTILDVNLLGVIDVTLNLLPLVRRAR----GRVVNVFSVMGRV-SLFGGGYCISKYG 182
Query: 604 VLQFSNCIGLEEHYAKSGVRVLSI 675
V FS+ + E Y GV+V I
Sbjct: 183 VEAFSDSLRRELSY--FGVKVAMI 204
>X55997-1|CAA39469.1| 373|Homo sapiens 3-beta-hydroxy-5-ene steroid
dehydrogenase protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>X53321-1|CAA37408.1| 373|Homo sapiens Hydroxysteroid dehydrogenase
/ Delta (5)->(4) Isomerase protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>S45679-1|AAB23543.1| 373|Homo sapiens 3 beta-hydroxysteroid
dehydrogenase/delta 5-delta 4 isomerase protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>M63397-1|AAA51662.1| 373|Homo sapiens 3-beta-hydroxysteroid
dehydrogenase/delta-5-4-isomerase protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>M38180-1|AAA51831.1| 373|Homo sapiens 3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4-isomerase protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>M35493-1|AAA51538.1| 373|Homo sapiens HSD3B protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>M27137-1|AAA36015.1| 373|Homo sapiens protein ( Human 3
beta-hydroxy-5-ene steroid dehydrogenase mRNA, complete
cds. ).
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>BC031999-1|AAH31999.1| 373|Homo sapiens hydroxy-delta-5-steroid
dehydrogenase, 3 beta- and steroid delta-isomerase 1
protein.
Length = 373
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 64
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 125 SIEVAG 130
>AL121995-3|CAI23359.1| 375|Homo sapiens hydroxy-delta-5-steroid
dehydrogenase, 3 beta-andotein 2 protein.
Length = 375
Score = 33.1 bits (72), Expect = 0.97
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Frame = +1
Query: 148 LITGAASGIGEGVVRLIL-ERGVKHVAILDVAEDSGRALENELNTKYGPNSVKFYKCDVT 324
L+TGA +G+ ++RL++ E+ +K + +LD A G L E + + + D+
Sbjct: 9 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKA--FGPELREEFSKLQNKTKLTVLEGDIL 66
Query: 325 DEELFLELFDTVK---NEQGYLDV--VINNAAIMNDSYKSYKKQIDINVTALVTGTL--K 483
DE V + +DV V + +IMN + K + ++ V A V +
Sbjct: 67 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 126
Query: 484 AIEIMG 501
+IE+ G
Sbjct: 127 SIEVAG 132
>AK024447-1|BAB15737.1| 145|Homo sapiens FLJ00037 protein protein.
Length = 145
Score = 33.1 bits (72), Expect = 0.97
Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Frame = -2
Query: 257 ALPESSATSKIATCLTPRSNISRTTPSPIPLAAPVISTIFPFH--DSITQCSTYKCIQQL 84
+LP SAT+ TC P + P P P+A P + P H D + +C ++Q+
Sbjct: 34 SLPFPSATNPKQTCCGPCPVSTVPAPPPQPVAHPCGAAAIPLHSKDDVERCKQKDLLEQM 93
Query: 83 I 81
+
Sbjct: 94 M 94
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,556,940
Number of Sequences: 237096
Number of extensions: 2281417
Number of successful extensions: 6424
Number of sequences better than 10.0: 279
Number of HSP's better than 10.0 without gapping: 5958
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6318
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -