Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30852
(436 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI000051A36C Cluster: PREDICTED: similar to Pyruvate d... 179 3e-44
UniRef50_Q99P95 Cluster: Pyruvate dehydrogenase kinase 1; n=2; T... 136 3e-31
UniRef50_Q15118 Cluster: [Pyruvate dehydrogenase [lipoamide]] ki... 133 2e-30
UniRef50_Q02332 Cluster: Probable [pyruvate dehydrogenase [lipoa... 121 8e-27
UniRef50_Q308M4 Cluster: Mitochondrial pyruvate dehydrogenase ki... 116 2e-25
UniRef50_A7S223 Cluster: Predicted protein; n=1; Nematostella ve... 115 5e-25
UniRef50_Q5BXW9 Cluster: SJCHGC05168 protein; n=1; Schistosoma j... 107 1e-22
UniRef50_UPI000155CFC2 Cluster: PREDICTED: similar to pyruvate d... 104 9e-22
UniRef50_Q4SMY8 Cluster: Chromosome 6 SCAF14544, whole genome sh... 103 2e-21
UniRef50_Q5DDA1 Cluster: SJCHGC06178 protein; n=1; Schistosoma j... 81 1e-14
UniRef50_Q4RNS3 Cluster: Chromosome 2 SCAF15010, whole genome sh... 67 1e-10
UniRef50_Q4P3N8 Cluster: Putative uncharacterized protein; n=3; ... 67 2e-10
UniRef50_A7EYF5 Cluster: Putative uncharacterized protein; n=1; ... 66 3e-10
UniRef50_A2QCL6 Cluster: Catalytic activity: ATP +; n=17; Dikary... 62 4e-09
UniRef50_Q6CB64 Cluster: Similar to tr|Q8X073 Neurospora crassa ... 60 3e-08
UniRef50_A3LY99 Cluster: Predicted protein; n=5; Saccharomycetal... 58 1e-07
UniRef50_Q6CID9 Cluster: Similar to ca|CA5524|IPF2861 Candida al... 54 2e-06
UniRef50_O82657 Cluster: Pyruvate dehydrogenase kinase; n=8; cor... 51 1e-05
UniRef50_Q6C089 Cluster: Yarrowia lipolytica chromosome F of str... 48 1e-04
UniRef50_O14874 Cluster: [3-methyl-2-oxobutanoate dehydrogenase ... 47 2e-04
UniRef50_Q756J1 Cluster: AER270Wp; n=1; Eremothecium gossypii|Re... 47 2e-04
UniRef50_A1CZZ3 Cluster: Pyruvate dehydrogenase kinase, putative... 47 2e-04
UniRef50_Q9P6P9 Cluster: [Pyruvate dehydrogenase [lipoamide]] ki... 46 3e-04
UniRef50_Q6PP98 Cluster: Mitochondrial pyruvate dehydrogenase ki... 46 3e-04
UniRef50_Q9T2P5 Cluster: Branched-chain alpha-ketoacid dehydroge... 44 0.001
UniRef50_Q94EY4 Cluster: Pyruvate dehydrogenase kinase-like prot... 44 0.002
UniRef50_A3GI33 Cluster: Probable pyruvate dehydrogenase kinase;... 41 0.013
UniRef50_Q4PDV9 Cluster: Putative uncharacterized protein; n=1; ... 39 0.053
UniRef50_Q4DWQ3 Cluster: Developmentally regulated phosphoprotei... 36 0.28
UniRef50_Q4P1C7 Cluster: Putative uncharacterized protein; n=1; ... 35 0.65
UniRef50_Q3E2V9 Cluster: TPR repeat:Tetratricopeptide TPR_4:Tetr... 34 1.5
UniRef50_Q4QD15 Cluster: Developmentally regulated phosphoprotei... 34 1.5
UniRef50_Q5XUC9 Cluster: Zona pellucida C related protein; n=4; ... 32 4.6
UniRef50_Q3KEI0 Cluster: FAD dependent oxidoreductase; n=1; Pseu... 32 4.6
UniRef50_A6LHG4 Cluster: Putative calcium dependent protease; n=... 32 4.6
UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome s... 32 6.0
UniRef50_Q4QAX9 Cluster: Pyruvate dehydrogenase (Lipoamide) kina... 32 6.0
UniRef50_Q7Q3R0 Cluster: ENSANGP00000007095; n=6; Culicidae|Rep:... 31 8.0
UniRef50_Q5CPM2 Cluster: Kelch repeat-containing proteins that i... 31 8.0
UniRef50_Q0IFS2 Cluster: Putative uncharacterized protein; n=1; ... 31 8.0
>UniRef50_UPI000051A36C Cluster: PREDICTED: similar to Pyruvate
dehydrogenase kinase CG8808-PA; n=1; Apis mellifera|Rep:
PREDICTED: similar to Pyruvate dehydrogenase kinase
CG8808-PA - Apis mellifera
Length = 416
Score = 179 bits (435), Expect = 3e-44
Identities = 84/120 (70%), Positives = 99/120 (82%)
Frame = +2
Query: 77 MRLAGAIFTNVTKMLDFYSQFNPSPLSIKQFIDFGLNACESKSFTFLKKELPVRLANIMK 256
M+L N++KMLDFYSQFNPSPLSIKQFIDFGL+ACE KSF FL+KELPVRLANIMK
Sbjct: 1 MKLTQKCLGNISKMLDFYSQFNPSPLSIKQFIDFGLSACERKSFIFLRKELPVRLANIMK 60
Query: 257 EIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
EI LLPENLL+MPSVG+VN Y SFE+I +FE++E + TL +FC+ LV IRNRH D+V
Sbjct: 61 EIHLLPENLLKMPSVGIVNNLYATSFEDIMQFEKVEVNDSTLDKFCQTLVKIRNRHKDIV 120
>UniRef50_Q99P95 Cluster: Pyruvate dehydrogenase kinase 1; n=2;
Theria|Rep: Pyruvate dehydrogenase kinase 1 - Phodopus
sungorus (Striped hairy-footed hamster) (Djungarian
hamster)
Length = 244
Score = 136 bits (328), Expect = 3e-31
Identities = 63/108 (58%), Positives = 85/108 (78%), Gaps = 2/108 (1%)
Frame = +2
Query: 119 LDFYSQFNPSPLSIKQFIDFG-LNACESKSFTFLKKELPVRLANIMKEIALLPENLLRMP 295
+DFY++F+PSPLS+KQF+DFG +NACE SF FL++ELPVRLANIMKEI+LLP+NLLR P
Sbjct: 4 VDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRRELPVRLANIMKEISLLPDNLLRTP 63
Query: 296 SVGLVNQWYERSFEEITRF-EQMEPDPPTLTQFCERLVHIRNRHADVV 436
SV LV WY +S +E+ F ++ D T+ +F + ++ IRNRH DV+
Sbjct: 64 SVQLVQSWYIQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVI 111
>UniRef50_Q15118 Cluster: [Pyruvate dehydrogenase [lipoamide]]
kinase isozyme 1, mitochondrial precursor; n=121;
Bilateria|Rep: [Pyruvate dehydrogenase [lipoamide]]
kinase isozyme 1, mitochondrial precursor - Homo sapiens
(Human)
Length = 436
Score = 133 bits (321), Expect = 2e-30
Identities = 63/112 (56%), Positives = 84/112 (75%), Gaps = 2/112 (1%)
Frame = +2
Query: 107 VTKMLDFYSQFNPSPLSIKQFIDFG-LNACESKSFTFLKKELPVRLANIMKEIALLPENL 283
V +DFY++F+PSPLS+KQF+DFG +NACE SF FL++ELPVRLANIMKEI+LLP+NL
Sbjct: 42 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 101
Query: 284 LRMPSVGLVNQWYERSFEEITRF-EQMEPDPPTLTQFCERLVHIRNRHADVV 436
LR PSV LV WY +S +E+ F ++ D + F + ++ IRNRH DV+
Sbjct: 102 LRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVI 153
>UniRef50_Q02332 Cluster: Probable [pyruvate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor; n=2;
Caenorhabditis|Rep: Probable [pyruvate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor -
Caenorhabditis elegans
Length = 401
Score = 121 bits (291), Expect = 8e-27
Identities = 57/122 (46%), Positives = 79/122 (64%)
Frame = +2
Query: 71 FKMRLAGAIFTNVTKMLDFYSQFNPSPLSIKQFIDFGLNACESKSFTFLKKELPVRLANI 250
F +L G ++ K LD+YSQF PS L+I+Q++DFG + S+TFLK EL VRLANI
Sbjct: 3 FSRKLLGPFVGSLAKKLDYYSQFQPSSLTIQQYLDFGRIGTSANSYTFLKNELLVRLANI 62
Query: 251 MKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHAD 430
M+E LLP LL+MPS +V+ WY SFE++ FE + P + +F ++L + RHA
Sbjct: 63 MQEFTLLPPKLLQMPSSKMVSNWYAESFEDLLLFEASDSSPEQVARFNDQLTVVLKRHAH 122
Query: 431 VV 436
VV
Sbjct: 123 VV 124
>UniRef50_Q308M4 Cluster: Mitochondrial pyruvate dehydrogenase
kinase isoenzyme 1; n=6; Eutheria|Rep: Mitochondrial
pyruvate dehydrogenase kinase isoenzyme 1 - Homo sapiens
(Human)
Length = 456
Score = 116 bits (280), Expect = 2e-25
Identities = 54/84 (64%), Positives = 69/84 (82%), Gaps = 1/84 (1%)
Frame = +2
Query: 107 VTKMLDFYSQFNPSPLSIKQFIDFG-LNACESKSFTFLKKELPVRLANIMKEIALLPENL 283
V +DFY++F+PSPLS+KQF+DFG +NACE SF FL++ELPVRLANIMKEI+LLP+NL
Sbjct: 42 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 101
Query: 284 LRMPSVGLVNQWYERSFEEITRFE 355
LR PSV LV WY +S +E+ F+
Sbjct: 102 LRTPSVQLVQSWYIQSLQELLDFK 125
>UniRef50_A7S223 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 420
Score = 115 bits (276), Expect = 5e-25
Identities = 58/120 (48%), Positives = 81/120 (67%)
Frame = +2
Query: 77 MRLAGAIFTNVTKMLDFYSQFNPSPLSIKQFIDFGLNACESKSFTFLKKELPVRLANIMK 256
MR++ A+ +++K++ YS++ S LSI+Q+ FG NA S+ F K ELPVRLA+I++
Sbjct: 1 MRISRALLRDISKLIQRYSRYQQSCLSIEQYTTFGKNAKPVDSYRFGKHELPVRLAHIIR 60
Query: 257 EIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
EI LLP+NLLRMPSV LV WY +SF E+ FE + D +F E L HI+ RH +VV
Sbjct: 61 EIDLLPKNLLRMPSVELVRSWYVQSFSELLEFE--DDDGEEANRFTETLAHIKQRHNNVV 118
>UniRef50_Q5BXW9 Cluster: SJCHGC05168 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05168 protein - Schistosoma
japonicum (Blood fluke)
Length = 234
Score = 107 bits (256), Expect = 1e-22
Identities = 59/123 (47%), Positives = 79/123 (64%), Gaps = 3/123 (2%)
Frame = +2
Query: 77 MRLAGAIFTNVTKMLDFYSQF---NPSPLSIKQFIDFGLNACESKSFTFLKKELPVRLAN 247
MRL+ A+ K + + +F +P+PLS+K+ I FG KS +FL ELPVRLAN
Sbjct: 1 MRLSQAVLILSGKYGEHFVRFGGYSPTPLSLKKLIAFGKVGSIQKSASFLADELPVRLAN 60
Query: 248 IMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHA 427
I++EI LLPE L+R PS LV +WYE+SF E+ FE++ D +L QF E L IR+RH
Sbjct: 61 ILQEIHLLPERLVRTPSASLVRRWYEQSFCELMDFEKVTWDEKSLNQFNELLASIRSRHT 120
Query: 428 DVV 436
VV
Sbjct: 121 TVV 123
>UniRef50_UPI000155CFC2 Cluster: PREDICTED: similar to pyruvate
dehydrogenase kinase; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to pyruvate dehydrogenase kinase -
Ornithorhynchus anatinus
Length = 275
Score = 104 bits (249), Expect = 9e-22
Identities = 49/85 (57%), Positives = 60/85 (70%), Gaps = 1/85 (1%)
Frame = +2
Query: 185 NACESKSFTFLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQME 364
NACE S+ FL+KELPVRLAN M+E+ LLP+NLL PSVGLV WY +SF E+ +E
Sbjct: 14 NACEKTSYMFLRKELPVRLANTMREVNLLPDNLLSRPSVGLVQSWYMQSFLELLDYENKS 73
Query: 365 P-DPPTLTQFCERLVHIRNRHADVV 436
P DP L F + L+ +RNRH DVV
Sbjct: 74 PEDPHVLDDFLQVLIKVRNRHNDVV 98
>UniRef50_Q4SMY8 Cluster: Chromosome 6 SCAF14544, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 6
SCAF14544, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 463
Score = 103 bits (246), Expect = 2e-21
Identities = 49/86 (56%), Positives = 63/86 (73%), Gaps = 1/86 (1%)
Frame = +2
Query: 77 MRLAGAIFTNVTKMLDFYSQFNPSPLSIKQFIDFGL-NACESKSFTFLKKELPVRLANIM 253
MR+ + N +++YS+F+PSPLSIKQF+DFG NACE S+ FL+KELPVRLAN M
Sbjct: 1 MRIFTFLLKNSNPKIEYYSKFSPSPLSIKQFLDFGRENACEKTSYMFLRKELPVRLANTM 60
Query: 254 KEIALLPENLLRMPSVGLVNQWYERS 331
KE+ LLP+ LL PSV LV +W + S
Sbjct: 61 KEVNLLPDKLLGQPSVRLVQKWLQVS 86
>UniRef50_Q5DDA1 Cluster: SJCHGC06178 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06178 protein - Schistosoma
japonicum (Blood fluke)
Length = 470
Score = 80.6 bits (190), Expect = 1e-14
Identities = 42/108 (38%), Positives = 65/108 (60%), Gaps = 1/108 (0%)
Frame = +2
Query: 116 MLDFYSQFNPSPLSIKQFIDFGLNACESKSFTFLKKELPVRLANIMKEIALLPENLLRMP 295
M++ YS+F P LS+K + FG A SKSF FLK ELPVR ANI++EI LLP L +
Sbjct: 16 MIEHYSKFTPVSLSLKSLLIFGETAPASKSFDFLKYELPVRFANIIREIQLLPNVLKKSK 75
Query: 296 SVGLVNQWYERSFEEITRFEQMEPDP-PTLTQFCERLVHIRNRHADVV 436
+ + YE +F+ + ++E P T+++F + + + +H+ VV
Sbjct: 76 PIKHICLLYEETFDTLLKYEGCSTHPTSTVSRFTDDIDILLQKHSSVV 123
>UniRef50_Q4RNS3 Cluster: Chromosome 2 SCAF15010, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
SCAF15010, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 455
Score = 67.3 bits (157), Expect = 1e-10
Identities = 30/44 (68%), Positives = 38/44 (86%), Gaps = 1/44 (2%)
Frame = +2
Query: 113 KMLDFYSQFNPSPLSIKQFIDFGL-NACESKSFTFLKKELPVRL 241
K +D+YS+F+PSPLS+KQF+DFG NACE SF FL++ELPVRL
Sbjct: 9 KDIDYYSKFSPSPLSMKQFLDFGSENACEKTSFAFLRQELPVRL 52
>UniRef50_Q4P3N8 Cluster: Putative uncharacterized protein; n=3;
Basidiomycota|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 473
Score = 66.9 bits (156), Expect = 2e-10
Identities = 35/107 (32%), Positives = 65/107 (60%), Gaps = 3/107 (2%)
Frame = +2
Query: 119 LDFYSQFNPSPLSIKQFIDFGLNACES---KSFTFLKKELPVRLANIMKEIALLPENLLR 289
L ++ F + +S++Q + FG N ++ +FL +ELP+RLA+ +KE+ LP +L +
Sbjct: 13 LHHFASFPQTGISLRQMVQFGRNPNPGTILQAGSFLAEELPIRLAHRVKELDELPHDLSK 72
Query: 290 MPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHAD 430
MPS+ V WY +SFEE+ F + P L++ ++L+ +++A+
Sbjct: 73 MPSIVKVKNWYAQSFEELVNFPK-----PRLSESVQKLLQNASKNAE 114
>UniRef50_A7EYF5 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 458
Score = 66.1 bits (154), Expect = 3e-10
Identities = 37/96 (38%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = +2
Query: 128 YSQFNPSPLSIKQFIDFGLNACESKSFT---FLKKELPVRLANIMKEIALLPENLLRMPS 298
YS F + +S++Q + FG F FL +ELP+RLA+ ++E++ LP+ L MPS
Sbjct: 16 YSHFPATGVSLRQMVQFGERPSTGTLFRASQFLSEELPIRLAHRVQELSDLPDGLNEMPS 75
Query: 299 VGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLV 406
+ V +WY +SFEEIT P P + ERL+
Sbjct: 76 IQKVKEWYAQSFEEITTL----PRPQLSSDVKERLM 107
>UniRef50_A2QCL6 Cluster: Catalytic activity: ATP +; n=17;
Dikarya|Rep: Catalytic activity: ATP + - Aspergillus
niger
Length = 438
Score = 62.5 bits (145), Expect = 4e-09
Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 3/90 (3%)
Frame = +2
Query: 128 YSQFNPSPLSIKQFIDFGLNACESKSFT---FLKKELPVRLANIMKEIALLPENLLRMPS 298
Y+ F + +S++Q + FG F FL +ELP+RLA+ ++++ LP+ L MPS
Sbjct: 15 YASFPATGVSLRQMVQFGDRPSTGTLFRASQFLSEELPIRLAHRVQDLGELPDGLSEMPS 74
Query: 299 VGLVNQWYERSFEEITRFEQMEPDPPTLTQ 388
+ V WY +SFEEI + PTLTQ
Sbjct: 75 IKKVQDWYAQSFEEIINLPR-----PTLTQ 99
>UniRef50_Q6CB64 Cluster: Similar to tr|Q8X073 Neurospora crassa
Related to pyruvate dehydrogenase kinase; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q8X073 Neurospora crassa
Related to pyruvate dehydrogenase kinase - Yarrowia
lipolytica (Candida lipolytica)
Length = 461
Score = 59.7 bits (138), Expect = 3e-08
Identities = 27/87 (31%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
Frame = +2
Query: 107 VTKMLDFYSQFNPSPLSIKQFIDFGLNACESKSFT---FLKKELPVRLANIMKEIALLPE 277
+ + + Y++F + +S++Q + FG F F+ +ELP+RLA+ ++++ LP+
Sbjct: 16 LAEKIKHYARFPATGVSLRQMVQFGSKPSAGTLFRASQFISEELPIRLAHRVRDLEDLPD 75
Query: 278 NLLRMPSVGLVNQWYERSFEEITRFEQ 358
L PS+ V WY +SF+E+T +Q
Sbjct: 76 GLSEQPSILRVRNWYAQSFDELTSLKQ 102
>UniRef50_A3LY99 Cluster: Predicted protein; n=5;
Saccharomycetales|Rep: Predicted protein - Pichia
stipitis (Yeast)
Length = 517
Score = 57.6 bits (133), Expect = 1e-07
Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Frame = +2
Query: 128 YSQFNPSPLSIKQFIDFGLNACESKSFT---FLKKELPVRLANIMKEIALLPENLLRMPS 298
Y+ + + +S++Q + FG N F F+ +ELP+RLA +K++ P +L +MPS
Sbjct: 18 YAAYKQTSISLRQMVQFGPNPSPGSIFLASQFIVEELPIRLALKVKDLENAPSDLNKMPS 77
Query: 299 VGLVNQWYERSFEEITRFEQMEPDP 373
V WY +SF+E+T + P
Sbjct: 78 TIKVKNWYAQSFQELTELPKPTISP 102
>UniRef50_Q6CID9 Cluster: Similar to ca|CA5524|IPF2861 Candida
albicans putative pyruvate dehydrogenase kinase; n=1;
Kluyveromyces lactis|Rep: Similar to ca|CA5524|IPF2861
Candida albicans putative pyruvate dehydrogenase kinase
- Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 512
Score = 53.6 bits (123), Expect = 2e-06
Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Frame = +2
Query: 128 YSQFNPSPLSIKQFIDFGLNACES---KSFTFLKKELPVRLANIMKEIALLPENLLRMPS 298
YS+ + +S++Q FG + K+ FL ELPVRLA+ +KE+ LP L ++
Sbjct: 16 YSETPQTAVSLRQMCQFGSHPTPGLMFKASCFLLNELPVRLAHRIKELESLPRGLNKVEE 75
Query: 299 VGLVNQWYERSFEEITRFEQME 364
V V WY +SF+++ F E
Sbjct: 76 VITVRDWYTQSFQDLYNFSHDE 97
>UniRef50_O82657 Cluster: Pyruvate dehydrogenase kinase; n=8; core
eudicotyledons|Rep: Pyruvate dehydrogenase kinase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 366
Score = 50.8 bits (116), Expect = 1e-05
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Frame = +2
Query: 152 LSIKQFIDFGLNACESK---SFTFLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWY 322
+S++ ++FG E S FL KELP+R+A E+ LP L P+V V WY
Sbjct: 29 VSLRYMMEFGSKPTERNLLISAQFLHKELPIRVARRAIELQTLPYGLSDKPAVLKVRDWY 88
Query: 323 ERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
SF ++ F +++ D F + + ++ RH +VV
Sbjct: 89 LESFRDMRAFPEIK-DSGDEKDFTQMIKAVKVRHNNVV 125
>UniRef50_Q6C089 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 469
Score = 47.6 bits (108), Expect = 1e-04
Identities = 27/110 (24%), Positives = 60/110 (54%), Gaps = 3/110 (2%)
Frame = +2
Query: 116 MLDFYSQFNPSPLSIKQFIDFGLNACESK---SFTFLKKELPVRLANIMKEIALLPENLL 286
+ ++Y++ +P P+S++Q FG E K S F++ ELP RLA+ ++++ LP +++
Sbjct: 62 LFNWYNK-SPHPVSLRQLAFFGRKLTEEKMIGSANFVRTELPTRLAHRIRDLQCLPFSVM 120
Query: 287 RMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
R + V + Y ++F + +F ++ +FC+ + + H ++
Sbjct: 121 RNEHMSQVYELYYQAFNQFRKFPAIKTLEDN-DKFCKLVSDLLLDHLTII 169
>UniRef50_O14874 Cluster: [3-methyl-2-oxobutanoate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor; n=34;
Eumetazoa|Rep: [3-methyl-2-oxobutanoate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor - Homo
sapiens (Human)
Length = 412
Score = 47.2 bits (107), Expect = 2e-04
Identities = 26/79 (32%), Positives = 48/79 (60%)
Frame = +2
Query: 200 KSFTFLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPT 379
KS +L++ELPVR+A+ +K LP + P++ V++ Y R+F+++T F ++ D
Sbjct: 89 KSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIK-DQAD 147
Query: 380 LTQFCERLVHIRNRHADVV 436
Q+C+ + + + H DVV
Sbjct: 148 EAQYCQLVRQLLDDHKDVV 166
>UniRef50_Q756J1 Cluster: AER270Wp; n=1; Eremothecium gossypii|Rep:
AER270Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 489
Score = 46.8 bits (106), Expect = 2e-04
Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 3/72 (4%)
Frame = +2
Query: 146 SPLSIKQFIDFGLNACESKSFT---FLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQ 316
+P+S+KQ FG + F FL +EL VRLA+ + E+ P L +M +V V
Sbjct: 24 TPVSLKQMCQFGQRPNPGELFKASCFLLEELQVRLAHRITEMDEFPSGLNKMENVLRVRN 83
Query: 317 WYERSFEEITRF 352
WY +SF+++ F
Sbjct: 84 WYIKSFQDLQEF 95
>UniRef50_A1CZZ3 Cluster: Pyruvate dehydrogenase kinase, putative;
n=15; Pezizomycotina|Rep: Pyruvate dehydrogenase kinase,
putative - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 441
Score = 46.8 bits (106), Expect = 2e-04
Identities = 34/113 (30%), Positives = 61/113 (53%), Gaps = 6/113 (5%)
Frame = +2
Query: 116 MLDFYSQFNPSPLSIKQFIDFGLNACESK---SFTFLKKELPVRLANIMKEIALLPENLL 286
+LD + + P+S++Q FG ES+ S +++ ELP R+A+ +++I LP ++
Sbjct: 41 ILDEWVEREIRPISLRQLTFFGRTLTESRLISSANYVRTELPTRIAHRLRDIQKLPYVVV 100
Query: 287 RMPSVGLVNQWYERSFEEITRFEQMEPDPPTL---TQFCERLVHIRNRHADVV 436
P + LV + Y ++FE RF ++ P+ TL +FC+ L H V+
Sbjct: 101 ANPHLSLVYELYYKAFE---RF-RVIPEIKTLEDNERFCDILRKTLKEHLVVI 149
>UniRef50_Q9P6P9 Cluster: [Pyruvate dehydrogenase [lipoamide]]
kinase, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: [Pyruvate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor -
Schizosaccharomyces pombe (Fission yeast)
Length = 425
Score = 46.4 bits (105), Expect = 3e-04
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
Frame = +2
Query: 119 LDFYSQFNPSPLSIKQFIDFGLNACESKSFT---FLKKELPVRLANIMKEIALLPENLLR 289
++ +Q+ + LS+KQ + FG N F FL+ ELP+RLA ++++ L L
Sbjct: 12 VNLLAQYPQTGLSLKQLVYFGKNPTPGTLFRAGLFLRDELPIRLARRIQDLQNLSPMLRS 71
Query: 290 MPSVGLVNQWYERSFEEITRFEQME 364
M + V Y RS EEI + +E
Sbjct: 72 MKRISSVKAAYGRSMEEIIELKGVE 96
>UniRef50_Q6PP98 Cluster: Mitochondrial pyruvate dehydrogenase
kinase isoform 2; n=18; Viridiplantae|Rep: Mitochondrial
pyruvate dehydrogenase kinase isoform 2 - Glycine max
(Soybean)
Length = 369
Score = 46.0 bits (104), Expect = 3e-04
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Frame = +2
Query: 152 LSIKQFIDFGLNACESK---SFTFLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWY 322
+S++ ++FG + S FL KEL +R+A E+ LP L + P+V V WY
Sbjct: 29 VSLRYMMEFGSKPTDKNLLISAQFLHKELAIRIARRAIELENLPYGLSQKPAVLKVRDWY 88
Query: 323 ERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
SF ++ F ++ + F E + I+ RH +VV
Sbjct: 89 VDSFRDLRAFPNIK-NVNDEQDFTEMIKAIKVRHNNVV 125
>UniRef50_Q9T2P5 Cluster: Branched-chain alpha-ketoacid
dehydrogenase kinase higher molecular weight isoform;
n=1; Rattus sp.|Rep: Branched-chain alpha-ketoacid
dehydrogenase kinase higher molecular weight isoform -
Rattus sp
Length = 461
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/79 (30%), Positives = 46/79 (58%)
Frame = +2
Query: 200 KSFTFLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPT 379
KS +L++ELPVR+A+ +K + +L+ V++ Y R+F+++T F ++ D
Sbjct: 89 KSGRYLQQELPVRIAHRIKGFVVFLSSLVATLPYCTVHELYIRAFQKLTDFPPIK-DQAD 147
Query: 380 LTQFCERLVHIRNRHADVV 436
Q+C+ + + + H DVV
Sbjct: 148 EAQYCQLVRQLLDDHKDVV 166
>UniRef50_Q94EY4 Cluster: Pyruvate dehydrogenase kinase-like
protein; n=2; Chlamydomonas|Rep: Pyruvate dehydrogenase
kinase-like protein - Chlamydomonas reinhardtii
Length = 512
Score = 43.6 bits (98), Expect = 0.002
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
Frame = +2
Query: 128 YSQFNPSPLSIKQFIDFGLNACES-----KSFTFLKKELPVRLANIMKEIALLPENLLRM 292
Y+ + LS++Q + FG NA KS ++++ELP RLA + ++ LLP ++
Sbjct: 58 YAAQDVEVLSLRQMLSFGRNAWNDPDKVLKSARYVQRELPKRLARRLLDLQLLPYIVVTN 117
Query: 293 PSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
P + V Y SFE + R + FC+ L + HA ++
Sbjct: 118 PHIKKVYNQYYISFETLRRVPTIRTLEEN-QDFCQLLRQHLDSHAPML 164
>UniRef50_A3GI33 Cluster: Probable pyruvate dehydrogenase kinase;
n=4; Saccharomycetaceae|Rep: Probable pyruvate
dehydrogenase kinase - Pichia stipitis (Yeast)
Length = 517
Score = 40.7 bits (91), Expect = 0.013
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Frame = +2
Query: 128 YSQFNPSPLSIKQFIDFGLNACESK---SFTFLKKELPVRLANIMKEIALLPENLLRMPS 298
Y + +P P+S++Q +G + K S F++ ELP+RLA ++++ LP ++
Sbjct: 109 YLKRDPHPVSLRQLAGYGNKLTKQKILNSANFVRIELPIRLAIRIRDLQTLPFGVVNNFH 168
Query: 299 VGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRH 424
+ + + Y F + Q+ +FCE L+ + + H
Sbjct: 169 LAQIYESYYHLFNAFRKIPQINTLDQN-DKFCETLLSLLDDH 209
>UniRef50_Q4PDV9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1737
Score = 38.7 bits (86), Expect = 0.053
Identities = 27/115 (23%), Positives = 57/115 (49%), Gaps = 5/115 (4%)
Frame = +2
Query: 107 VTKMLDFYSQFNPSPLSIKQFIDFGLNACES-----KSFTFLKKELPVRLANIMKEIALL 271
+ K+L+ ++ + ++++Q I FG KS +++ ELPVR+A+ ++++ L
Sbjct: 1182 LNKVLEQWAAKPATRMTLRQLIFFGRTLGRDREKILKSANYVRTELPVRIAHRIRDLQAL 1241
Query: 272 PENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHADVV 436
P ++ + V Q Y +FE RF ++ +FC L + + H ++
Sbjct: 1242 PFVVMTNQHLEDVYQKYWSAFETFRRFPHIKTMDDN-ERFCNLLRRLLDDHLTII 1295
>UniRef50_Q4DWQ3 Cluster: Developmentally regulated phosphoprotein,
putative; n=2; Trypanosoma|Rep: Developmentally
regulated phosphoprotein, putative - Trypanosoma cruzi
Length = 423
Score = 36.3 bits (80), Expect = 0.28
Identities = 24/72 (33%), Positives = 36/72 (50%)
Frame = +2
Query: 212 FLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTLTQF 391
F ELPV LA ++ I LP L MPSV LV Y SF+++ + + + D ++ F
Sbjct: 80 FCHMELPVLLARLIMAIDTLPCGLNAMPSVLLVRNTYLDSFKKLIKCDFPDND-ESILHF 138
Query: 392 CERLVHIRNRHA 427
+ I H+
Sbjct: 139 RRVVADIEEAHS 150
>UniRef50_Q4P1C7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 493
Score = 35.1 bits (77), Expect = 0.65
Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 11/112 (9%)
Frame = +2
Query: 116 MLDFYSQFNPSPLSIKQFIDFGLNACESK-------SFTFLKKELPVRLANIMKEIALLP 274
+L Y P+PL+++Q + G ++ S +ELP+RLA + LP
Sbjct: 68 LLTHYLSLQPAPLTLRQLMAQGGKPGQALTPERLVLSAQHTHRELPIRLARRVGGFRALP 127
Query: 275 ENLLRMPSVGLVNQWYERSFEEITRFEQM--EPDPPTLTQFCERLV--HIRN 418
+ P + + + Y SFE + +F Q+ + D T E LV H +N
Sbjct: 128 FIVGSNPFISRIARLYASSFETLVKFGQIQTQEDNQRFTDVIEDLVSAHAQN 179
>UniRef50_Q3E2V9 Cluster: TPR repeat:Tetratricopeptide
TPR_4:Tetratricopeptide TPR_4; n=2; Chloroflexus|Rep:
TPR repeat:Tetratricopeptide TPR_4:Tetratricopeptide
TPR_4 - Chloroflexus aurantiacus J-10-fl
Length = 1766
Score = 33.9 bits (74), Expect = 1.5
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Frame = +2
Query: 218 KKELPVRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQ---MEPDPPTLTQ 388
K++LP A + + + PEN+ +G+ +W R + I FEQ + PD P L
Sbjct: 53 KRDLPAATATFEQVLQVDPENIPAHVGLGMAYEWQGRLDKAIAEFEQALEIRPDMPELRA 112
Query: 389 FCERL 403
RL
Sbjct: 113 QLVRL 117
>UniRef50_Q4QD15 Cluster: Developmentally regulated
phosphoprotein-like protein; n=3; Leishmania|Rep:
Developmentally regulated phosphoprotein-like protein -
Leishmania major
Length = 452
Score = 33.9 bits (74), Expect = 1.5
Identities = 28/105 (26%), Positives = 45/105 (42%)
Frame = +2
Query: 116 MLDFYSQFNPSPLSIKQFIDFGLNACESKSFTFLKKELPVRLANIMKEIALLPENLLRMP 295
++D Y+ L IK+ + N + F K LP+ LA+ + + LP L MP
Sbjct: 56 LVDLYASRKMKRLDIKRILGI-FNDRAYHAPIFCHKALPIILAHFITGLDRLPSGLNAMP 114
Query: 296 SVGLVNQWYERSFEEITRFEQMEPDPPTLTQFCERLVHIRNRHAD 430
S+ V RSF+++ + D + F L I HA+
Sbjct: 115 SILAVRATLLRSFQKLINCKIPATD-DQVQHFRRVLEDIDEEHAE 158
>UniRef50_Q5XUC9 Cluster: Zona pellucida C related protein; n=4;
Danio rerio|Rep: Zona pellucida C related protein -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 552
Score = 32.3 bits (70), Expect = 4.6
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Frame = -2
Query: 432 TSACRFLMWTRRSQNWVSVGGSGSI---CSKRVISSNERS 322
TSA +F + +R +WV +GG ++ C KR S+ ER+
Sbjct: 194 TSATKFCNYNKRKSSWVDLGGQTTVCDCCGKRCRSAIERA 233
>UniRef50_Q3KEI0 Cluster: FAD dependent oxidoreductase; n=1;
Pseudomonas fluorescens PfO-1|Rep: FAD dependent
oxidoreductase - Pseudomonas fluorescens (strain PfO-1)
Length = 344
Score = 32.3 bits (70), Expect = 4.6
Identities = 10/27 (37%), Positives = 17/27 (62%)
Frame = +2
Query: 308 VNQWYERSFEEITRFEQMEPDPPTLTQ 388
+ W+E+ E++ RF ++ PDPP Q
Sbjct: 315 LGDWFEKDMEQLRRFYRLHPDPPRWLQ 341
>UniRef50_A6LHG4 Cluster: Putative calcium dependent protease; n=1;
Parabacteroides distasonis ATCC 8503|Rep: Putative
calcium dependent protease - Parabacteroides distasonis
(strain ATCC 8503 / DSM 20701 / NCTC11152)
Length = 763
Score = 32.3 bits (70), Expect = 4.6
Identities = 12/44 (27%), Positives = 22/44 (50%)
Frame = -2
Query: 384 VSVGGSGSICSKRVISSNERSYHWLTKPTEGIRSRFSGSSAISF 253
V GGS S + + +E +Y W+ P S + S++++F
Sbjct: 601 VGAGGSASFTASPIFMEDEGNYQWMVSPNTASMSAYRYSNSVTF 644
>UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 21
SCAF11909, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1114
Score = 31.9 bits (69), Expect = 6.0
Identities = 25/88 (28%), Positives = 37/88 (42%)
Frame = -2
Query: 402 RRSQNWVSVGGSGSICSKRVISSNERSYHWLTKPTEGIRSRFSGSSAISFIMFASLTGSS 223
R WVS GS +C R + ER ++PT G+ FSG S++ G +
Sbjct: 562 RPPSRWVSSSGSLLLC--RCSLAVERRRSCCSEPTSGVPEEFSGYSSL---------GQN 610
Query: 222 FFRNVNDLLSQAFRPKSMNCLMDNGEGL 139
F L ++ P + D+G GL
Sbjct: 611 QFSQYYSALPPSYVPAGLPSSEDHGSGL 638
>UniRef50_Q4QAX9 Cluster: Pyruvate dehydrogenase (Lipoamide) kinase,
putative; n=3; Leishmania|Rep: Pyruvate dehydrogenase
(Lipoamide) kinase, putative - Leishmania major
Length = 483
Score = 31.9 bits (69), Expect = 6.0
Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Frame = +2
Query: 233 VRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEITRFEQMEPDPPTL--TQFCERLV 406
VR+A ++ + P L +MP + ++ +WY+ SF ++ + P P T C+R+V
Sbjct: 153 VRIARRVRHLNHAPYGLSQMPGIQMLKKWYQWSFHDV----RSTPVPTTRDGCYRCDRMV 208
Query: 407 -HIRNRHADV 433
+ RH +V
Sbjct: 209 RRVFLRHYNV 218
>UniRef50_Q7Q3R0 Cluster: ENSANGP00000007095; n=6; Culicidae|Rep:
ENSANGP00000007095 - Anopheles gambiae str. PEST
Length = 522
Score = 31.5 bits (68), Expect = 8.0
Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Frame = +2
Query: 101 TNVTKMLDFYSQFNPSPLS-IKQFIDFGLNACES 199
T++ + L+F+ N SP +K F +FGLN CE+
Sbjct: 81 TSMRQKLNFFEMANESPAKMLKLFDEFGLNLCEA 114
>UniRef50_Q5CPM2 Cluster: Kelch repeat-containing proteins that is
fused to a HSP90-like ATpase; n=2; Cryptosporidium|Rep:
Kelch repeat-containing proteins that is fused to a
HSP90-like ATpase - Cryptosporidium parvum Iowa II
Length = 1248
Score = 31.5 bits (68), Expect = 8.0
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = -2
Query: 285 SRFSGSSAISFIMFASLTGSSFFRNVNDLLSQAFRPKSMNCLMDNGEGLNCE*KSSIFVT 106
S FS S + F A LT +SF VN + + K+ ++DNG GL E + +F
Sbjct: 760 SPFSSSQSWIFGAIAHLTDNSFSTEVNSSIFEISICKNYISVIDNGSGLCYEDLNRLFKH 819
Query: 105 F 103
F
Sbjct: 820 F 820
>UniRef50_Q0IFS2 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 2805
Score = 31.5 bits (68), Expect = 8.0
Identities = 15/60 (25%), Positives = 30/60 (50%)
Frame = +2
Query: 164 QFIDFGLNACESKSFTFLKKELPVRLANIMKEIALLPENLLRMPSVGLVNQWYERSFEEI 343
+ I++ + + FTF KE+PV +A + + +N LRM L ++W + ++
Sbjct: 761 ELIEWNKESGKWDKFTFFGKEIPVFVAAFDRTFVVYDDNYLRMGYRSLDSEWQSKVIAKV 820
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 410,523,026
Number of Sequences: 1657284
Number of extensions: 7731106
Number of successful extensions: 22262
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 21750
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 22250
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 21496989549
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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