Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30818
(627 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 150 2e-35
UniRef50_Q7KT12 Cluster: CG9331-PE, isoform E; n=14; Endopterygo... 149 5e-35
UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to ENSANGP000... 128 1e-28
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 123 3e-27
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 119 5e-26
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 118 9e-26
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 113 2e-24
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 109 4e-23
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 109 4e-23
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 106 5e-22
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 103 3e-21
UniRef50_Q7PMI6 Cluster: ENSANGP00000021069; n=1; Anopheles gamb... 102 8e-21
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 101 1e-20
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 99 4e-20
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v... 100 6e-20
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 99 8e-20
UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate reductase/... 98 1e-19
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 2e-19
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 97 2e-19
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 3e-19
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 96 5e-19
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 96 7e-19
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 95 9e-19
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 95 2e-18
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 94 2e-18
UniRef50_Q0UH86 Cluster: Putative uncharacterized protein; n=1; ... 94 2e-18
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 93 4e-18
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 4e-18
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 93 7e-18
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 93 7e-18
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 92 9e-18
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 92 9e-18
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 92 9e-18
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 92 1e-17
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 91 3e-17
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 90 3e-17
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 90 3e-17
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 90 5e-17
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 89 6e-17
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 89 6e-17
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 89 1e-16
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 2e-16
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 2e-16
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 87 2e-16
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 87 3e-16
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 3e-16
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 3e-16
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 87 4e-16
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 4e-16
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 87 4e-16
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 86 8e-16
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 86 8e-16
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 8e-16
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 85 1e-15
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 85 1e-15
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 84 2e-15
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 84 2e-15
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 84 3e-15
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 84 3e-15
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 3e-15
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 84 3e-15
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 83 4e-15
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 83 5e-15
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 83 7e-15
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 82 9e-15
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 82 9e-15
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 82 9e-15
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 82 1e-14
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 81 2e-14
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 81 2e-14
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 81 2e-14
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 81 2e-14
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 81 2e-14
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 81 3e-14
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 80 4e-14
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 4e-14
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 80 4e-14
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 80 5e-14
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 79 9e-14
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 79 9e-14
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 79 9e-14
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 79 9e-14
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 79 1e-13
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 79 1e-13
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 78 2e-13
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 78 2e-13
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 2e-13
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 78 2e-13
UniRef50_Q89Y67 Cluster: Oxidoreductase; n=14; Alphaproteobacter... 77 3e-13
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 77 3e-13
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi... 77 3e-13
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 77 3e-13
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 3e-13
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 77 3e-13
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 77 5e-13
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 5e-13
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 77 5e-13
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 5e-13
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 6e-13
UniRef50_Q54DP1 Cluster: Gluconate 2-dehydrogenase; n=1; Dictyos... 76 6e-13
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 76 6e-13
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 76 8e-13
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 75 1e-12
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 75 1e-12
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 75 1e-12
UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1; Rhi... 75 1e-12
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 75 1e-12
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 2e-12
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 75 2e-12
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 2e-12
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 74 2e-12
UniRef50_Q11BV4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 74 2e-12
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 74 2e-12
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 3e-12
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 74 3e-12
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 74 3e-12
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 4e-12
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 73 4e-12
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 4e-12
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 4e-12
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 4e-12
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 4e-12
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 73 6e-12
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 6e-12
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 73 6e-12
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 73 7e-12
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 72 1e-11
UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10; Bacteria... 72 1e-11
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 72 1e-11
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_A0R5A8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_P53839 Cluster: Putative 2-hydroxyacid dehydrogenase YN... 71 2e-11
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 71 2e-11
UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 71 2e-11
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 71 3e-11
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 70 4e-11
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 70 4e-11
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 4e-11
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 70 5e-11
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 70 5e-11
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 70 5e-11
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 70 5e-11
UniRef50_P30799 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 70 5e-11
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 69 7e-11
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 7e-11
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 69 7e-11
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 7e-11
UniRef50_Q9A6E7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 9e-11
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 9e-11
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 69 1e-10
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 68 2e-10
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 68 2e-10
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 68 2e-10
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_A5V984 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 68 2e-10
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 67 3e-10
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 67 3e-10
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 67 3e-10
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 67 3e-10
UniRef50_A5FIN4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 3e-10
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 67 3e-10
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 67 4e-10
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 67 4e-10
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 67 4e-10
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 67 4e-10
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 67 4e-10
UniRef50_Q47748 Cluster: D-specific alpha-keto acid dehydrogenas... 67 4e-10
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 66 5e-10
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 66 5e-10
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 66 5e-10
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 66 5e-10
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 5e-10
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 66 5e-10
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 66 6e-10
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 66 6e-10
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 66 9e-10
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 65 1e-09
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 65 1e-09
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 65 1e-09
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 65 1e-09
UniRef50_A0IKR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 65 1e-09
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 65 1e-09
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 65 1e-09
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 65 1e-09
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 64 2e-09
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 64 2e-09
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 64 2e-09
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 64 2e-09
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 64 2e-09
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 64 2e-09
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 64 3e-09
UniRef50_Q7UKR1 Cluster: Phosphoglycerate dehydrogenase SerA2-pu... 64 3e-09
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 64 3e-09
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 64 3e-09
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 64 3e-09
UniRef50_Q4P4C6 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 64 3e-09
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 64 3e-09
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 64 3e-09
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 63 5e-09
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 63 5e-09
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 63 6e-09
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 6e-09
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 63 6e-09
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 63 6e-09
UniRef50_A0NJK9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 63 6e-09
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 63 6e-09
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 63 6e-09
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 63 6e-09
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 63 6e-09
UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;... 62 8e-09
UniRef50_Q0UHH1 Cluster: Putative uncharacterized protein; n=1; ... 62 8e-09
UniRef50_Q5V4Z5 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 62 8e-09
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 62 8e-09
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 62 1e-08
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 62 1e-08
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 62 1e-08
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 62 1e-08
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 62 1e-08
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A4GXI6 Cluster: D-lactate dehydrogenase; n=2; Lactobaci... 62 1e-08
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 62 1e-08
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 62 1e-08
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_UPI0000586D88 Cluster: PREDICTED: hypothetical protein,... 62 1e-08
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 62 1e-08
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 62 1e-08
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 62 1e-08
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 62 1e-08
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 61 2e-08
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 61 2e-08
UniRef50_A1W7E2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 61 2e-08
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q1DT79 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 60 3e-08
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 60 3e-08
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 60 3e-08
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 60 3e-08
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 60 4e-08
UniRef50_Q97FN7 Cluster: D-lactate dehydrogenase; n=1; Clostridi... 60 4e-08
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 60 4e-08
UniRef50_Q1FLB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 4e-08
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 60 4e-08
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 6e-08
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 6e-08
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 59 7e-08
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 7e-08
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 59 7e-08
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 59 7e-08
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 7e-08
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 7e-08
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 59 7e-08
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 1e-07
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 59 1e-07
UniRef50_Q9Z569 Cluster: Putative dehydrogenase; n=4; Actinomyce... 58 1e-07
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 1e-07
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 1e-07
UniRef50_Q9YCJ2 Cluster: Putative glyoxylate reductase; n=1; Aer... 58 1e-07
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 58 2e-07
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 58 2e-07
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 58 2e-07
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 58 2e-07
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 58 2e-07
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 58 2e-07
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 58 2e-07
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 58 2e-07
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 58 2e-07
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 3e-07
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 3e-07
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 57 3e-07
UniRef50_A2R1X3 Cluster: Remark: D(--)-Mandelate dehydrogenase; ... 57 3e-07
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 57 4e-07
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 57 4e-07
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07
UniRef50_UPI000023E18D Cluster: hypothetical protein FG04024.1; ... 56 5e-07
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 56 5e-07
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 56 5e-07
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 56 5e-07
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 5e-07
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 5e-07
UniRef50_A1HMH1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 5e-07
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 5e-07
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 56 5e-07
UniRef50_Q0V2B9 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 56 7e-07
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 56 7e-07
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 56 9e-07
UniRef50_Q03Q04 Cluster: Phosphoglycerate dehydrogenase related ... 56 9e-07
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 9e-07
UniRef50_A3XKE7 Cluster: D-lactate dehydrogenase; n=3; Bacteria|... 56 9e-07
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 9e-07
UniRef50_Q53Q48 Cluster: Putative uncharacterized protein; n=2; ... 56 9e-07
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 56 9e-07
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 1e-06
UniRef50_Q7Z019 Cluster: Putative D-lactate dehydrogenase; n=1; ... 55 1e-06
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 55 1e-06
UniRef50_P33160 Cluster: Formate dehydrogenase; n=54; cellular o... 55 1e-06
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 55 2e-06
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ... 55 2e-06
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 2e-06
UniRef50_Q87JV4 Cluster: D-lactate dehydrogenase; n=6; Vibrio|Re... 54 2e-06
UniRef50_A5IAP7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_Q97IU7 Cluster: Lactate dehydrogenase; n=5; Clostridial... 54 3e-06
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 54 3e-06
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 54 3e-06
UniRef50_Q2BJD9 Cluster: Phosphoglycerate dehydrogenase; n=1; Ne... 54 3e-06
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 54 3e-06
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 54 3e-06
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 54 4e-06
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 54 4e-06
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_A0AFI6 Cluster: Complete genome; n=1; Listeria welshime... 54 4e-06
UniRef50_A5AR84 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 54 4e-06
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 53 5e-06
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 53 5e-06
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 53 5e-06
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 53 5e-06
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 53 5e-06
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 5e-06
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 53 5e-06
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 5e-06
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 53 5e-06
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 53 6e-06
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_A3I3U4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 53 6e-06
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 52 9e-06
UniRef50_Q98J55 Cluster: Mlr2095 protein; n=5; Rhizobiales|Rep: ... 52 9e-06
UniRef50_Q82ZZ6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 9e-06
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 52 9e-06
UniRef50_A7CWK1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 9e-06
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 52 9e-06
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 52 9e-06
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 52 9e-06
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 52 1e-05
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 52 1e-05
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 52 1e-05
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A5BY55 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 51 2e-05
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 51 2e-05
UniRef50_UPI000038E31A Cluster: hypothetical protein Faci_030017... 51 3e-05
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_Q82W00 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 51 3e-05
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_A5V093 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 51 3e-05
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 50 3e-05
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 50 3e-05
UniRef50_Q08SH8 Cluster: Glyoxylate reductase; n=1; Stigmatella ... 50 3e-05
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 50 3e-05
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 50 5e-05
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 50 5e-05
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 50 5e-05
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 50 5e-05
UniRef50_Q026D8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 50 5e-05
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_Q22CX9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 50 6e-05
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 50 6e-05
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 50 6e-05
UniRef50_Q5KLD5 Cluster: Oxidoreductase, putative; n=2; Filobasi... 50 6e-05
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 49 8e-05
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 49 8e-05
UniRef50_Q0HS14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_A1SI21 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 8e-05
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 49 8e-05
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 49 8e-05
UniRef50_A2R5K8 Cluster: Remark: blast hit against patented sequ... 49 8e-05
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 49 8e-05
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 49 1e-04
UniRef50_A5TUT7 Cluster: Dehydrogenase; n=4; Fusobacterium nucle... 49 1e-04
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 49 1e-04
UniRef50_Q89F87 Cluster: Bll6814 protein; n=9; Bradyrhizobiaceae... 48 1e-04
UniRef50_Q88TW9 Cluster: Phosphoglycerate dehydrogenase; n=1; La... 48 1e-04
UniRef50_Q01QI5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 1e-04
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 48 1e-04
UniRef50_A5IXT8 Cluster: D-lactate dehydrogenase; n=3; Mycoplasm... 48 1e-04
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 48 1e-04
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 48 1e-04
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 48 2e-04
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 48 2e-04
UniRef50_A4B0Y8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 2e-04
UniRef50_P72357 Cluster: D-lactate dehydrogenase; n=28; Bacilli|... 48 2e-04
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 48 2e-04
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 48 2e-04
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q2AHD3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q03Z77 Cluster: Lactate dehydrogenase related 2-hydroxy... 48 2e-04
UniRef50_A6DPW5 Cluster: 2-hydroxyacid-family dehydrogenase; n=2... 48 2e-04
UniRef50_Q5UZP4 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 48 2e-04
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 47 3e-04
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 47 3e-04
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc... 47 3e-04
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 47 4e-04
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q3W8K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q1M7M0 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 47 4e-04
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_A6GPV1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 46 6e-04
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 46 6e-04
UniRef50_A4AKX0 Cluster: Putative dehydrogenase; n=1; marine act... 46 6e-04
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 46 6e-04
UniRef50_A0YGL0 Cluster: Dehydrogenase; n=1; marine gamma proteo... 46 6e-04
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 7e-04
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 46 7e-04
UniRef50_A7LVV2 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_Q6Z8P7 Cluster: Putative uncharacterized protein P0708B... 46 7e-04
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 7e-04
UniRef50_Q82ZC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q3M599 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q1ISS3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_Q1GWA2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A1RMU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A2D764 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A1CP94 Cluster: Glycerate dehydrogenase; n=4; Trichocom... 46 0.001
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 45 0.001
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 45 0.001
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 45 0.001
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 45 0.002
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 45 0.002
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 45 0.002
UniRef50_Q0V699 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002
UniRef50_A1D255 Cluster: Glycerate dehydrogenase; n=1; Neosartor... 45 0.002
>UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n=1;
Aedes aegypti|Rep: Glyoxylate/hydroxypyruvate reductase
- Aedes aegypti (Yellowfever mosquito)
Length = 345
Score = 150 bits (364), Expect = 2e-35
Identities = 67/150 (44%), Positives = 104/150 (69%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R+EIL+ PG ++W++ + + +LD AG QLK+VST+++G ++ N E R R I L
Sbjct: 62 RDEILRATPGAEGILWLTADRLDDAVLDLAGPQLKVVSTLTSGMDYVNAEAFRKRKIALG 121
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
+TP V++ VA++AVGL+++A+RRF E ++ +WE +LGQD+ STVGI+G G
Sbjct: 122 HTPKVVNNPVADIAVGLMIAAARRFHEGRMKILNSDWEATPQWMLGQDVTGSTVGIVGFG 181
Query: 532 GIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
GIGQ + +RL GFD+ R +Y+G +KPEA+
Sbjct: 182 GIGQTIARRLQGFDIGRLLYTGRTKKPEAE 211
>UniRef50_Q7KT12 Cluster: CG9331-PE, isoform E; n=14;
Endopterygota|Rep: CG9331-PE, isoform E - Drosophila
melanogaster (Fruit fly)
Length = 366
Score = 149 bits (361), Expect = 5e-35
Identities = 79/187 (42%), Positives = 120/187 (64%), Gaps = 1/187 (0%)
Frame = +1
Query: 46 KNLKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWIS 225
K KVLV+ + P + +L+++ ++Q + + + R E+L+ I G ++W
Sbjct: 45 KAFKVLVTHPEVPQEGIDLLKENCEIVQVQSV-------PINRAELLEKIRGVDGVLWGG 97
Query: 226 NLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLL 405
+ P+ E LDAAG QLK +ST+SAG ++ + E++ R I L +TP VL+ AVA++AVGLL
Sbjct: 98 HEPLNAEALDAAGPQLKSISTMSAGIDYVDVPEVKRRKIPLGHTPTVLNTAVADLAVGLL 157
Query: 406 LSASRRFTENLDQVRRGEWE-IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVAR 582
++ASRRF E + +WE + +LGQD+RDSTVG G GGIGQA+ KRLSGFD+ +
Sbjct: 158 IAASRRFHEGRKTIDNDKWENYHLNWLLGQDIRDSTVGFYGFGGIGQAIAKRLSGFDIDK 217
Query: 583 FIYSGHR 603
+Y+ R
Sbjct: 218 VLYTTRR 224
>UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to
ENSANGP00000021023; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021023 - Nasonia
vitripennis
Length = 519
Score = 128 bits (308), Expect = 1e-28
Identities = 62/117 (52%), Positives = 85/117 (72%)
Frame = +1
Query: 259 AGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENL 438
AG++LKI+ST SAGY+H N +E++ RGI++ + P VLS AVAE AV LLL A+RR E
Sbjct: 266 AGSKLKIISTPSAGYDHMNIQEIKKRGIKVGHAPKVLSGAVAETAVFLLLGAARRAHEGR 325
Query: 439 DQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREK 609
+ +G+ E GF +LG DLR+ TVGI+GLG IG+ +VKRL F++ +F Y+GH K
Sbjct: 326 LLLEQGKVENGFQWLLGHDLRNKTVGIVGLGNIGEEIVKRLKPFEIKKFFYTGHSRK 382
>UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate
reductase; n=49; Eumetazoa|Rep: Glyoxylate
reductase/hydroxypyruvate reductase - Homo sapiens
(Human)
Length = 328
Score = 123 bits (297), Expect = 3e-27
Identities = 64/151 (42%), Positives = 95/151 (62%), Gaps = 1/151 (0%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+E+ + + G L+ + + + ILDAAG LK++ST+S G +H +E++ RGI++
Sbjct: 43 KELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGY 102
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL-GQDLRDSTVGIIGLG 531
TP+VL+ AE+AV LLL+ RR E +++V+ G W L G L STVGIIGLG
Sbjct: 103 TPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLG 162
Query: 532 GIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
IGQA+ +RL F V RF+Y+G + +PE A
Sbjct: 163 RIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193
>UniRef50_Q4PP80 Cluster: Putative glyoxylate
reductase/hydroxypyruvate reductase; n=1; Lysiphlebus
testaceipes|Rep: Putative glyoxylate
reductase/hydroxypyruvate reductase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 325
Score = 119 bits (287), Expect = 5e-26
Identities = 70/190 (36%), Positives = 104/190 (54%), Gaps = 1/190 (0%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
KVLV+ D P + L IL++ + ++ + + + R E L ++ + +
Sbjct: 5 KVLVTRGDIPESGLSILKNKYDLI------CWNKTTPIPRTEFLSMVKDVDGIFCLLTDK 58
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I EIL AG++LK+VST+S G +H N L+ RGI + TP VL+ A AE+ +GLLL+
Sbjct: 59 IDEEILSTAGSKLKVVSTMSVGLDHLNLNALKTRGIHVGYTPGVLTDATAELTIGLLLAT 118
Query: 415 SRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
SR+ +R GEW + G L +STVGI+GLG IG V + L F V + +Y
Sbjct: 119 SRKIIAAEHALRNGEWTSWSPNWMCGPGLANSTVGIVGLGRIGARVGEYLKPFGVNKILY 178
Query: 592 SGHREKPEAK 621
S EK +AK
Sbjct: 179 SSRTEKTDAK 188
>UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 323
Score = 118 bits (285), Expect = 9e-26
Identities = 68/181 (37%), Positives = 105/181 (58%), Gaps = 1/181 (0%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
+VLV+ P A+++L+D + L++ + + R E+L + G A+ +
Sbjct: 4 QVLVTRR-VPDEAIQLLKD-----ANCQLDYWESDEPIPRNELLNRVKGKHAIFCLLTEK 57
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I E+LDA G QLK+V+T+S GY+H N +E+ RG+QL TP VL+ A A + V LLL+
Sbjct: 58 IDAEVLDACGPQLKVVATMSVGYDHVNTKEIEKRGLQLGFTPGVLTDATATLNVALLLAV 117
Query: 415 SRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
SRR E + + G W + G L+ STVG++G G IG AV +RL+ F V +F+Y
Sbjct: 118 SRRIVEAAAEAKNGGWGTWKPMWMTGATLKGSTVGVVGFGRIGIAVCERLAPFGVCKFLY 177
Query: 592 S 594
+
Sbjct: 178 N 178
>UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p -
Drosophila melanogaster (Fruit fly)
Length = 362
Score = 113 bits (273), Expect = 2e-24
Identities = 68/196 (34%), Positives = 107/196 (54%), Gaps = 1/196 (0%)
Frame = +1
Query: 40 MTKNLKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVW 219
M+ KV V+ D + L++L +S ++ E + + R E+++++ G AL
Sbjct: 38 MSSQHKVYVTRPDVDDSGLELLR------KSCQVSTWHETNPVPRSELIRVVAGKDALYC 91
Query: 220 ISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVG 399
+ E+LDAAG QLK V+T+S GY+H + EE R RGI++ TP+VL+ A AE+ +
Sbjct: 92 ALTDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIRVGFTPDVLTDATAELTLA 151
Query: 400 LLLSASRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
LLL+ +RR E QV G W+ + GQ L+ S VG++G G IGQ + R+ F
Sbjct: 152 LLLATNRRLFEANKQVYNGGWKSWAPMWMCGQGLKGSRVGLLGFGRIGQEIAARIVPFKP 211
Query: 577 ARFIYSGHREKPEAKA 624
Y+ +P+ A
Sbjct: 212 TEITYTTRSLRPKEAA 227
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 109 bits (263), Expect = 4e-23
Identities = 64/192 (33%), Positives = 104/192 (54%), Gaps = 1/192 (0%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
KVLV+ P L +L++ L+ + + + E++K I A+ +
Sbjct: 379 KVLVTRATVPEAGLNLLKNECD------LDTWEHTEPIPKPELIKRIKEADAIFCLLTDK 432
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I E+L AAG++LK+++T+S G +H + + +++R I + TP VL+ A AE+ + LLL+
Sbjct: 433 IDEEVLSAAGSKLKVIATMSVGVDHLDLKAIKSRNIPIGYTPGVLTDATAELTMALLLAT 492
Query: 415 SRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
SRR E + RGEW+ + G + S +GI+GLG IG V + L F VA+ +Y
Sbjct: 493 SRRLIEANRAIYRGEWKAWCPTWMTGPKISGSNIGIVGLGRIGLRVSEYLKSFGVAKILY 552
Query: 592 SGHREKPEAKAL 627
+ EKP A L
Sbjct: 553 TSRTEKPAATKL 564
>UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Pyrobaculum aerophilum|Rep: D-3-phosphoglycerate
dehydrogenase - Pyrobaculum aerophilum
Length = 323
Score = 109 bits (263), Expect = 4e-23
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
Frame = +1
Query: 58 VLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLG--REEILKLIPGCSALVWISNL 231
+ VS +P + K LE+ V Y + G ST G +E ++ C ALV
Sbjct: 4 IFVSREGFPESMYKKLEEVGRV--EVYRHGGSPWSTRGVPKEVLIDAARRCEALVIFIGD 61
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
I E+LDA G +LKIVST S G +H + E + +G+ + +TP VL AVA++AVGLL++
Sbjct: 62 VIDKEVLDA-GEKLKIVSTASVGVDHIDVEYAKRKGVVVAHTPYVLVDAVADLAVGLLIA 120
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+R+ +R G + + ++G +LR GI+GLG IG A+ +RL FD+ Y
Sbjct: 121 VTRKIALGDRLIRSGAADAVWGSLMGVNLRGKRAGIVGLGNIGVAIARRLKAFDI-EVAY 179
Query: 592 SGHREKPEAK 621
R KPE +
Sbjct: 180 WSRRRKPEVE 189
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 106 bits (254), Expect = 5e-22
Identities = 71/194 (36%), Positives = 109/194 (56%), Gaps = 5/194 (2%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
KV ++ + P +K+LED F V +G E + RE +LK + ALV + +
Sbjct: 4 KVFIT-REIPEVGIKMLEDEFEVEV-----WGDE-KEIPREILLKKVKEVDALVTMLSER 56
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I E+ + A +L+IV+ + GY++ + EE RGI +TNTP+VL+ A A++A LLL+
Sbjct: 57 IDKEVFENA-PKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLAT 115
Query: 415 SRRFTENLDQVRRGEWE---IGFDK--VLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVA 579
+R + VR GEW+ + + LG D+ T+GIIGLG IGQA+ KR GF++
Sbjct: 116 ARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNM- 174
Query: 580 RFIYSGHREKPEAK 621
R +Y K E +
Sbjct: 175 RILYYSRTRKEEVE 188
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 103 bits (247), Expect = 3e-21
Identities = 55/151 (36%), Positives = 90/151 (59%), Gaps = 1/151 (0%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
REE+ +L+ G L+ + + I E++D AG QL +VS + G+N+ + + + RG+ +
Sbjct: 121 REELCRLVKGRHGLLTMLSDRIDGELMDVAGEQLCVVSNYAVGFNNIDVDAAKTRGVVVG 180
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGL 528
NTP+VL+ A A++AV LL +ASR +QVR GEW+ LG + D T+GI+G+
Sbjct: 181 NTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTGWLGVEPSDKTLGIVGM 240
Query: 529 GGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
G IG+A KRL G +Y+ ++ + +
Sbjct: 241 GRIGKATAKRLVGGWGMNLLYTSRSDQGDVE 271
>UniRef50_Q7PMI6 Cluster: ENSANGP00000021069; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000021069 - Anopheles gambiae
str. PEST
Length = 311
Score = 102 bits (244), Expect = 8e-21
Identities = 69/191 (36%), Positives = 100/191 (52%), Gaps = 1/191 (0%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWIS-NL 231
+VLV+ + P AL+ L V+ ++F R +IL L PG L+W S +
Sbjct: 7 RVLVTHHQVQPVALQRLRKDCDVIVPA-VDFPS------RAQILDLCPGVDGLLWTSYKM 59
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
+ E+LDA G QLK +S G + + +EL R I L +TP + + AVA++AVGL+LS
Sbjct: 60 KLDREVLDACGAQLKAISLTMNGVDCVDVKELARRNIPLGHTPYIPNRAVADLAVGLMLS 119
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+ R EI + + Q ++ ST+GI+G GGIGQ + RL FDV +Y
Sbjct: 120 VNERLLSTAG-------EICYQR---QPIQGSTIGIVGFGGIGQLIASRLQAFDVDCILY 169
Query: 592 SGHREKPEAKA 624
G R K A A
Sbjct: 170 CGPRPKASADA 180
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 101 bits (243), Expect = 1e-20
Identities = 55/148 (37%), Positives = 89/148 (60%), Gaps = 2/148 (1%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L REE++ + G A++ + + EILDAAG Q KI++ + G+N+ N + RG+
Sbjct: 35 LTREELMNAVKGRDAVITLLTDNVDAEILDAAGPQCKIIANYAVGFNNFNLDAATKRGVI 94
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKV--LGQDLRDSTVGI 519
+TNTP VL A A A LLL+ ++R +E+ VR G+W+ G+ + +GQD+ T+GI
Sbjct: 95 MTNTPGVLDKATATHAWALLLATAKRISESERYVREGKWK-GWSPMTFIGQDVDGKTLGI 153
Query: 520 IGLGGIGQAVVKRLSGFDVARFIYSGHR 603
GLG IG ++ + FD+ + IY+ +
Sbjct: 154 AGLGRIGTMFARKAAAFDM-KVIYTNEQ 180
>UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5;
Burkholderiales|Rep: 2-hydroxyacid dehydrogenase -
Ralstonia solanacearum UW551
Length = 331
Score = 99 bits (238), Expect = 4e-20
Identities = 64/192 (33%), Positives = 107/192 (55%), Gaps = 3/192 (1%)
Frame = +1
Query: 58 VLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPI 237
VLV+ +P A + L +HF V + + L E+++ + G ++ + I
Sbjct: 5 VLVTRATFPDIANR-LREHFDVTDN------PSDTILSPSELIERLQGKQGVMSTGSERI 57
Query: 238 TNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSAS 417
+LDA LK V V GYN+ + ARG+ +TNTP+VL+ A+ L+L+ +
Sbjct: 58 DAALLDAC-PGLKAVCNVGVGYNNVDVAACTARGVVVTNTPDVLTQTTADFGFALMLATA 116
Query: 418 RRFTENLDQVRRGEWE-IG-FDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDVARFI 588
RR TE+ VRRGEW+ G ++++LG D+ +T+GI+G+G IGQA+ +R + GF++
Sbjct: 117 RRITESERFVRRGEWQKTGIYNQMLGSDIYGATLGILGMGRIGQAIARRAALGFEMQVIY 176
Query: 589 YSGHREKPEAKA 624
++ PE +A
Sbjct: 177 HNRSPLTPETEA 188
>UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus
vulgaris|Rep: D-lactate dehydrogenase - Octopus vulgaris
(Octopus)
Length = 324
Score = 99.5 bits (237), Expect = 6e-20
Identities = 53/166 (31%), Positives = 89/166 (53%), Gaps = 3/166 (1%)
Frame = +1
Query: 139 LNFGQEGSTLGREEILKLIPG--CSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHC 312
++F + +E++K + G + L+ + + E+ +AAG LK+VST+S GY H
Sbjct: 26 IDFWDSDEAIPHQELVKNVKGKGYAGLLCLLTDQVDAEVFEAAGPSLKVVSTLSVGYEHI 85
Query: 313 NPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDK-VLG 489
+ + +AR I N + + V+E AV L L+ SRR E + VR G W + +LG
Sbjct: 86 DLKACKARNIIACNLSKISTDCVSEFAVTLALAVSRRIEEGIAAVRNGSWGLWKPMWILG 145
Query: 490 QDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
+ T+G++G+G IG V +R+ F ++R IY +E A+ L
Sbjct: 146 SSFANRTIGVLGMGRIGYGVARRMKAFCISRLIYHDIKESSFAQEL 191
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 99.1 bits (236), Expect = 8e-20
Identities = 57/153 (37%), Positives = 86/153 (56%), Gaps = 1/153 (0%)
Frame = +1
Query: 157 GSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRAR 336
G L + E+LK + G L+ I E++D A LK+++ S G +H + E R R
Sbjct: 56 GLFLPKAELLKRVEGAVGLIPTVEDRIDAEVMDRA-KGLKVIACYSVGVDHVDLEAARER 114
Query: 337 GIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGF-DKVLGQDLRDSTV 513
GI++T+TP VL+ A A++ + LLL+ +RR E R G W + +LG DL+ T+
Sbjct: 115 GIRVTHTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPELLLGLDLQGLTL 174
Query: 514 GIIGLGGIGQAVVKRLSGFDVARFIYSGHREKP 612
G++G+G IGQAV KR F + R +Y KP
Sbjct: 175 GLVGMGRIGQAVAKRALAFGM-RVVYHARTPKP 206
>UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate
reductase/hydroxypyruvate reductase; n=2; Mammalia|Rep:
PREDICTED: glyoxylate reductase/hydroxypyruvate
reductase - Macaca mulatta
Length = 191
Score = 98.3 bits (234), Expect = 1e-19
Identities = 52/125 (41%), Positives = 79/125 (63%), Gaps = 1/125 (0%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+E+ + + G L+ + + + ILDAAG LK++ST+S G +H +E++ RGI++
Sbjct: 43 KELERGVAGAHGLLCLLSDRVDKRILDAAGANLKVISTLSVGVDHLALDEIKKRGIRVGY 102
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL-GQDLRDSTVGIIGLG 531
TP+VL+ A AE+AV LLL+ RR E +++V+ G W L G L STVGI+GLG
Sbjct: 103 TPDVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIVGLG 162
Query: 532 GIGQA 546
IG+A
Sbjct: 163 RIGEA 167
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/192 (33%), Positives = 107/192 (55%), Gaps = 2/192 (1%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
K+LV+ P L++L+DH + + + +E+ + + AL+ + +
Sbjct: 3 KILVAGK-IPEIGLELLKDHDVEMYDKE-------ELISLDELTERVKDKDALLSLLSTK 54
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+T E++DAA + LKIV+ AGY++ + +GI +TNTP V + A AE+ LLL+A
Sbjct: 55 VTKEVIDAAPS-LKIVANYGAGYDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAA 113
Query: 415 SRRFTENLDQVRRGEWEIGFDKV--LGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFI 588
+RR E D + R G+ + LG+++ T+GIIGLG IG+AV KR F + +
Sbjct: 114 ARRIPEG-DTLCRTTGFNGWAPLFFLGREVHGKTIGIIGLGEIGKAVAKRAKAFGM-NIL 171
Query: 589 YSGHREKPEAKA 624
Y+G KPEA++
Sbjct: 172 YTGPNRKPEAES 183
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 97.5 bits (232), Expect = 2e-19
Identities = 55/178 (30%), Positives = 100/178 (56%), Gaps = 3/178 (1%)
Frame = +1
Query: 97 KILEDHFTVLQSRYL--NFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQ 270
K+ E+ T LQ +Y + E + RE +L+ S ++ + + PI E+ + +
Sbjct: 36 KLPEEVLTSLQEKYEVEMWDDENIAVPREILLEKAGEASGILSMLSDPIDRELFEKS-PN 94
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
LK+V+ ++ G+++ + + + + + NTP+VL+ A++ GL+++A+RR E VR
Sbjct: 95 LKVVANLAVGFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIEADKYVR 154
Query: 451 RGEWEIGFDKVL-GQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
G+W+ ++ G D+ TVGIIG+G IG+A +R GFD+ +Y KPEA+
Sbjct: 155 EGKWKSWSPLLMAGTDIHHKTVGIIGMGSIGEAFARRAKGFDM-NILYHNRSRKPEAE 211
>UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pseudomonas putida
W619|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas putida W619
Length = 318
Score = 97.1 bits (231), Expect = 3e-19
Identities = 69/184 (37%), Positives = 103/184 (55%), Gaps = 3/184 (1%)
Frame = +1
Query: 82 PPTALKILEDHFTVLQSRYLNFGQEGSTLG-REEILKLIPGCSALVWISNLPITNEILDA 258
P ++ ++L D L+ RY +F + L R+ L + L+ S LP+ E+LD
Sbjct: 9 PISSAEVLAD----LEQRY-HFRRFDQPLADRDGFLAALATADGLIG-STLPLDAELLDH 62
Query: 259 AGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENL 438
A + LK++++VSAG+++ LR RGI LTNTP+ ++ A+ LL+ A+RR E
Sbjct: 63 APS-LKVIASVSAGFDNYPLGYLRDRGICLTNTPDAVTETTADTGFMLLMMAARRACELA 121
Query: 439 DQVRRGEWEIGFD-KVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDVARFIYSGHREKP 612
VR G W G D G D+ T+GI+GLG IG AV +R GF + +YSG+ KP
Sbjct: 122 QLVRDGGWTQGIDASRFGMDVHGKTLGIVGLGRIGAAVARRAHFGFGMP-VLYSGNSAKP 180
Query: 613 EAKA 624
E +A
Sbjct: 181 EYEA 184
>UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 357
Score = 97.1 bits (231), Expect = 3e-19
Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 3/140 (2%)
Frame = +1
Query: 202 CSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAV 381
C A++ +S + E LDAAG LK++ST+S GY+H + + RG+++ NTP VL AV
Sbjct: 55 CGAVICLSE-KVDAEFLDAAGASLKVISTMSVGYDHIDLALCKERGVRVGNTPRVLDDAV 113
Query: 382 AEVAVGLLLSASRRFTENLDQVRRGEWEIG---FDKVLGQDLRDSTVGIIGLGGIGQAVV 552
AEV + L L +R+ + VR+GEW G +R T+G +G G I Q++
Sbjct: 114 AEVCLLLALMVTRQVPLAIRTVRQGEWPQNPWTPTCFTGPQIRGKTIGFLGFGNISQSLC 173
Query: 553 KRLSGFDVARFIYSGHREKP 612
K L F AR +Y+ + +P
Sbjct: 174 KLLVAFKPARIVYTTSKPRP 193
>UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Rep:
Glyoxylate reductase - Roseiflexus sp. RS-1
Length = 340
Score = 96.3 bits (229), Expect = 5e-19
Identities = 53/158 (33%), Positives = 89/158 (56%), Gaps = 1/158 (0%)
Frame = +1
Query: 154 EGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRA 333
E + + RE +L+ + ++ + + E+L AA +LK+V+ ++ GY++ + L A
Sbjct: 31 EANPVPRETLLRAVADVDGILTLLTDRVDTELL-AAAPRLKVVANMAVGYDNVDLPALTA 89
Query: 334 RGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDK-VLGQDLRDST 510
RG+ LTNTP+VL+ A++ L+L+ASRR E + G W ++GQD+ +T
Sbjct: 90 RGVLLTNTPDVLTETTADLVWALILAASRRVVEGHRLIAAGGWTTWSPMFMVGQDVHGAT 149
Query: 511 VGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
+GI+G G IG AV +R GF + +Y R P +A
Sbjct: 150 LGIVGAGRIGSAVARRAVGFGMP-ILYHNRRPSPSLEA 186
>UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified
Gammaproteobacteria|Rep: Glyoxylate reductase - marine
gamma proteobacterium HTCC2143
Length = 326
Score = 95.9 bits (228), Expect = 7e-19
Identities = 56/151 (37%), Positives = 86/151 (56%), Gaps = 3/151 (1%)
Frame = +1
Query: 151 QEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELR 330
Q ++ R+E++ + G ++ + I E+++++ LK VS VS G +H + L
Sbjct: 28 QGKGSIPRDELMARVEGVDGIICLLTERIDGELINSS-KNLKAVSCVSVGVDHVDVGTLT 86
Query: 331 ARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGF---DKVLGQDLR 501
ARGI L +TP VL A A++A GLLL+A+RR + VR G W+ LG +
Sbjct: 87 ARGIPLGHTPGVLVDATADLAFGLLLAAARRIPQGDRHVRTGGWQGASWSPKAFLGCSVA 146
Query: 502 DSTVGIIGLGGIGQAVVKRLSGFDVARFIYS 594
T+GIIGLG IGQA+ +R +GFD+ +S
Sbjct: 147 GKTLGIIGLGDIGQALARRAAGFDMPVIAWS 177
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/152 (36%), Positives = 87/152 (57%), Gaps = 2/152 (1%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L +EE++K A+V PI E + + + KI++ + GYN+ + E + RGI
Sbjct: 32 LSKEEMIKRAEYADAIVTQLRDPIDKEFIYSL-KKAKIIANYAVGYNNIDIEAAKERGIY 90
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDK--VLGQDLRDSTVGI 519
+TNTP VL+ A A++A L+L+ +RR E+ VR G++ +G+ LG DL T+G+
Sbjct: 91 VTNTPGVLTEATADIAFALILAVARRIVESDKFVREGKF-VGWKPKLFLGYDLYGKTLGV 149
Query: 520 IGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
IG+G IGQAV +R GF + +Y PE
Sbjct: 150 IGMGRIGQAVARRALGFGM-NIVYYNRNRLPE 180
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 94.7 bits (225), Expect = 2e-18
Identities = 53/151 (35%), Positives = 88/151 (58%), Gaps = 1/151 (0%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L ++E++K+IP LV S +T +I++A G LKI++ G ++ + ++ + +GI+
Sbjct: 33 LEKDELMKIIPEVDVLVVRSATKVTADIIEA-GKNLKIIARAGIGLDNIDVQKAKEKGIK 91
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL-GQDLRDSTVGII 522
+ NTP +P+VAE+A+GL+L+ +R ++ G+WE K L G++L T+G+I
Sbjct: 92 VLNTPGASAPSVAELAMGLMLACARHIARATVSLKEGKWE---KKALKGKELLGKTLGLI 148
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
G G IGQ V KR F + Y KPE
Sbjct: 149 GFGNIGQEVAKRALAFGMKIIAYD--PAKPE 177
>UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=15; Firmicutes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Bacillus anthracis
Length = 330
Score = 94.3 bits (224), Expect = 2e-18
Identities = 61/160 (38%), Positives = 91/160 (56%), Gaps = 3/160 (1%)
Frame = +1
Query: 151 QEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELR 330
++ + R+ +L+ I L+ + I E+L+AA LK+VS +S GY++ + + +
Sbjct: 39 EQNEKVPRDVLLEKIQDKDGLLNFGSA-INEELLEAA-PNLKVVSNISVGYDNFDLQAMA 96
Query: 331 ARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEW--EIGFDKVLGQDLRD 504
+ TNTP VL VA++ L+LSA RR E V+ GEW EIG + G D+
Sbjct: 97 KHNVIGTNTPYVLDDTVADLVFALMLSAGRRVCELDSYVKNGEWNAEIGKEH-FGLDVHH 155
Query: 505 STVGIIGLGGIGQAVVKRLS-GFDVARFIYSGHREKPEAK 621
ST+GIIG+G IG+AV KR GFD+ +Y R K EA+
Sbjct: 156 STIGIIGMGRIGEAVAKRAKFGFDM-DVLYYNRRRKEEAE 194
>UniRef50_Q0UH86 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 339
Score = 94.3 bits (224), Expect = 2e-18
Identities = 52/143 (36%), Positives = 86/143 (60%), Gaps = 3/143 (2%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R +L+ G + ++ + + + E++ AAG QLK +++ S G +H + E L+ R I+L
Sbjct: 40 RSWLLENAQGATGILVMLSDQVNEELVQAAGHQLKAIASFSVGTDHVDREALKKRNIRLG 99
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEW-EIGFDKVL--GQDLRDSTVGII 522
TP L+ AVA++ V L+L A RR E + +V +GEW ++ + +L G +R +TVG +
Sbjct: 100 YTPTCLTDAVADLTVMLILMAQRRGGEAISKVTKGEWPQMPWHPLLMTGPQIRGATVGFL 159
Query: 523 GLGGIGQAVVKRLSGFDVARFIY 591
G G I QA + RL GF + + IY
Sbjct: 160 GFGRIAQASLVRLMGFGIKKAIY 182
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 93.5 bits (222), Expect = 4e-18
Identities = 46/121 (38%), Positives = 76/121 (62%), Gaps = 1/121 (0%)
Frame = +1
Query: 268 QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQV 447
+LK+VST++ GY++ + +E RG+ + +TP VL+ A A++ LL++ RR E++D V
Sbjct: 66 RLKVVSTMAVGYDNIDIKEATKRGVSVGHTPGVLTEATADLTFALLMATGRRLRESIDYV 125
Query: 448 RRGEWEI-GFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
R +W+ G + GQ + +T+GIIG+G IGQAV KR GF++ ++ R + K
Sbjct: 126 RNDQWKSWGPFMLTGQAIYGTTLGIIGMGRIGQAVAKRAKGFNMTLLYHNRSRNEQAEKE 185
Query: 625 L 627
L
Sbjct: 186 L 186
>UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Thermococcaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Pyrococcus abyssi
Length = 333
Score = 93.5 bits (222), Expect = 4e-18
Identities = 54/149 (36%), Positives = 85/149 (57%), Gaps = 4/149 (2%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE+ ++IP ++ IT +IL+ A +LK++S SAGY+H + EE RGI +T
Sbjct: 34 EELKEIIPELDGIIIAPVTRITKDILERA-ERLKVISCQSAGYDHVDVEEATKRGIYVTK 92
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWE----IGFDKVLGQDLRDSTVGII 522
+LS AVAE A+GLL+S R+ +R G+WE + + + L VGI+
Sbjct: 93 VSGLLSEAVAEFALGLLISLMRKIHYADSFIREGKWESHTFVWREFKEVETLYGKEVGIV 152
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHREK 609
G+G IG+A+ +RL F + +S HR++
Sbjct: 153 GMGAIGKAIARRLKPFGCEIYYWSRHRKE 181
>UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 320
Score = 92.7 bits (220), Expect = 7e-18
Identities = 54/171 (31%), Positives = 98/171 (57%), Gaps = 2/171 (1%)
Frame = +1
Query: 100 ILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKI 279
+ + FT L+S+Y EG EE+L++IP L + + P+ E++D A ++LK+
Sbjct: 10 MFREGFTELESKYEVTFPEGRDFTYEEVLEMIPEYDVLCSMFDFPVNKELIDHA-SKLKM 68
Query: 280 VSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRG- 456
V+ + GYN+ + +GI + NTP+ ++ A +A+GL+L +RR TE ++RR
Sbjct: 69 VANYAVGYNNIDVAYCLEKGITVANTPDPVTAPTANLALGLMLDVARRITECDRKLRREG 128
Query: 457 -EWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
++G + LG ++ T+GIIG+G IG+A+ +R + + +Y R+
Sbjct: 129 LGMKVGVLENLGINVTGKTLGIIGMGRIGKALARRANACGM-EVLYHNRRQ 178
>UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2;
Hyphomicrobium methylovorum|Rep: Glycerate dehydrogenase
- Hyphomicrobium methylovorum
Length = 322
Score = 92.7 bits (220), Expect = 7e-18
Identities = 50/152 (32%), Positives = 86/152 (56%), Gaps = 2/152 (1%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+E+++ AL+ N E++D +K +ST S G++H + + +ARGI++ N
Sbjct: 38 DEMIETAKSVDALLITLNEKCRKEVIDRIPENIKCISTYSIGFDHIDLDACKARGIKVGN 97
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFD--KVLGQDLRDSTVGIIGL 528
P+ ++ A AE+A+ LLL ++RR E +R W G++ +++G+ L + T+GI G
Sbjct: 98 APHGVTVATAEIAMLLLLGSARRAGEGEKMIRTRSWP-GWEPLELVGEKLDNKTLGIYGF 156
Query: 529 GGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
G IGQA+ KR GFD+ + HR +A
Sbjct: 157 GSIGQALAKRAQGFDMDIDYFDTHRASSSDEA 188
>UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1;
Oceanobacillus iheyensis|Rep: 2-ketogluconate reductase
- Oceanobacillus iheyensis
Length = 324
Score = 92.3 bits (219), Expect = 9e-18
Identities = 55/115 (47%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Frame = +1
Query: 223 SNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGL 402
S L + +LD A LKIV+ +S GY++ EEL RGI TNTP+VL+ VA+ GL
Sbjct: 51 SKLRVDGHLLDQA-PHLKIVTNISVGYDNLEIEELTKRGIMATNTPDVLTDTVADTVFGL 109
Query: 403 LLSASRRFTENLDQ-VRRGEWE--IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
LL+ SRR E LDQ V+ G W+ IG + + G D+ T+GIIG+G IG AV +R
Sbjct: 110 LLATSRRICE-LDQYVKLGRWDENIG-EHLFGVDVHHKTLGIIGMGRIGLAVAER 162
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 92.3 bits (219), Expect = 9e-18
Identities = 48/142 (33%), Positives = 84/142 (59%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L EE++ L+ AL+ + N +T ++++A G +LK++S GY++ + + +GI
Sbjct: 40 LSAEELIPLVKDADALI-VGNDKVTEDVINA-GKKLKVISRYGVGYDNVDLNAAKKKGIV 97
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+TNTPN + +VA++ +GL+L +R V+ G W+ +++G ++ T+GIIG
Sbjct: 98 VTNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWK----RIMGTEIYGKTLGIIG 153
Query: 526 LGGIGQAVVKRLSGFDVARFIY 591
LG IG+ V KR GFD+ Y
Sbjct: 154 LGKIGKGVAKRAKGFDMNVLCY 175
>UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3;
Archaea|Rep: Gluconate 2-dehydrogenase - Picrophilus
torridus
Length = 310
Score = 92.3 bits (219), Expect = 9e-18
Identities = 49/127 (38%), Positives = 79/127 (62%), Gaps = 2/127 (1%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I +EI+DAA +LK++ST S GY+H + + +R I++ TP+VL+ + A+ GL++
Sbjct: 52 IDSEIIDAA-KKLKVISTYSVGYDHIDVKYALSRNIKIGYTPDVLTESTADFIFGLIICI 110
Query: 415 SRRFTENLDQVRRGEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFI 588
+RR + + +WE + D +LG D+ T+GI+GLG IG AV++R SGFD+ I
Sbjct: 111 ARRICSGYETIISNKWEYRWKPDFMLGHDVYGKTLGILGLGRIGHAVMRRASGFDM-NVI 169
Query: 589 YSGHREK 609
Y E+
Sbjct: 170 YYNRTER 176
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 91.9 bits (218), Expect = 1e-17
Identities = 51/134 (38%), Positives = 76/134 (56%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L REE L+ +P AL+ S + E+LDAAG +LK++ G ++ + E RG+
Sbjct: 46 LEREETLRRLPDYDALITRSRTKVDRELLDAAGPRLKVIGRGGVGVDNIDLEYASRRGLL 105
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P + + AE+AV L++A+R T + + R GEW+ K LG +L D T+GI+G
Sbjct: 106 VLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWD---RKFLGLELTDKTLGIVG 162
Query: 526 LGGIGQAVVKRLSG 567
LG IG V R G
Sbjct: 163 LGRIGSIVADRAQG 176
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 91.1 bits (216), Expect = 2e-17
Identities = 57/153 (37%), Positives = 86/153 (56%)
Frame = +1
Query: 118 TVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSA 297
T+L R N +G+T +++K L+ + + IT EI+D QLK++ A
Sbjct: 16 TMLSDRGYNVVLDGAT-PLADLVKANSDAEVLI-VRSEKITPEIIDLL-PQLKLIVRAGA 72
Query: 298 GYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFD 477
G+N + + R I + NTP S AVAE V ++L+ASR R+G+WE
Sbjct: 73 GFNTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKGDWE--KS 130
Query: 478 KVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
K +G++L TVGI+GLG IGQ +VKRL+GF++
Sbjct: 131 KFMGRELTGKTVGILGLGHIGQLLVKRLAGFEM 163
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/142 (37%), Positives = 78/142 (54%), Gaps = 2/142 (1%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R +++ I G ALV I ++DAA L+ ++T S GY+H + R RGI +
Sbjct: 70 RRALIRAISGAHALVCFPYDVIDAGVMDAA-PDLETIATYSVGYDHIDVAHARGRGITVG 128
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWE--IGFDKVLGQDLRDSTVGIIG 525
TP+VL+ A A++ + L+L RR TE +R G W G D LG D+ T+GI+G
Sbjct: 129 YTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYGADDYLGTDVGGKTLGILG 188
Query: 526 LGGIGQAVVKRLSGFDVARFIY 591
+G IG V KR + F + + IY
Sbjct: 189 MGRIGSRVAKRAAAFGM-KVIY 209
>UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular
organisms|Rep: Glyoxylate reductase - Burkholderia
mallei (Pseudomonas mallei)
Length = 342
Score = 90.2 bits (214), Expect = 3e-17
Identities = 44/124 (35%), Positives = 76/124 (61%), Gaps = 1/124 (0%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
AA +L++VS ++ GYN+ + A + TNTP+VL+ A+ L+++A+RR TE+
Sbjct: 73 AAAPRLRVVSNMAVGYNNFDIGAFDAAHVLGTNTPDVLTETTADFGWALMMAAARRITES 132
Query: 436 LDQVRRGEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKP 612
+R G+W + +D LG D+ +T+G++G+G IGQA+ +R GF + ++ R P
Sbjct: 133 EHWLRAGQWRKWSYDSFLGADIHGATLGVLGMGRIGQALARRARGFGMRVIYHNRSRVAP 192
Query: 613 EAKA 624
E +A
Sbjct: 193 EIEA 196
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 90.2 bits (214), Expect = 3e-17
Identities = 53/138 (38%), Positives = 77/138 (55%)
Frame = +1
Query: 178 EILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNT 357
E+ K P ++ + + +T E++D LK V AGYN + + R++ I + NT
Sbjct: 36 ELAKAHPDTEGMI-VRSEKLTPEVIDLF-PNLKAVVRAGAGYNTIDIQYARSKDITVMNT 93
Query: 358 PNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGI 537
P S AVAE AVG+++S +R F E R GEW+ ++ G +L TVGI G G I
Sbjct: 94 PGANSNAVAEEAVGMMISCARFFIEGDRSTRAGEWKKA--QLQGFELTGKTVGIAGFGNI 151
Query: 538 GQAVVKRLSGFDVARFIY 591
GQ + KRLSGF+V +Y
Sbjct: 152 GQLLAKRLSGFEVDILVY 169
>UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2;
Alphaproteobacteria|Rep: Glycolate reductase - alpha
proteobacterium HTCC2255
Length = 319
Score = 89.8 bits (213), Expect = 5e-17
Identities = 48/136 (35%), Positives = 80/136 (58%), Gaps = 1/136 (0%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
+EEI+ A+V + +++++ G +LKI++ S G +HC+ L + I +T
Sbjct: 37 KEEIISASFEFDAIVPCHSEVFSSDVVSKFGPRLKIIANHSVGVDHCDLAALNEKNILVT 96
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGL 528
NTP+VLS A AE+A+ L+L A+R + VR G W+ ++G+ L + +GIIG+
Sbjct: 97 NTPDVLSDATAEIAMLLMLGAARHAVLGDEIVRSGNWKNWSPSFMVGKQLTGARIGIIGM 156
Query: 529 GGIGQAVVKRLSGFDV 576
G +GQA K+ GFD+
Sbjct: 157 GRVGQAFAKKARGFDM 172
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 89.4 bits (212), Expect = 6e-17
Identities = 52/154 (33%), Positives = 87/154 (56%), Gaps = 1/154 (0%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
+ RE L + +A V + I E+ A QLK+++ ++ G+++ + + G+
Sbjct: 34 MSRESFLANVEDATACVITLSEHIDEEVFLRA-QQLKVIANMAVGFDNIDISLAKKHGVV 92
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL-GQDLRDSTVGII 522
+TNTP+VL+ AE+ L+L+ +RR E ++ G+W+ +L G+D+ +TVGI
Sbjct: 93 VTNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYLLSGKDVYGATVGIF 152
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
G+G IG+A +RL GFD AR IY H K + A
Sbjct: 153 GMGDIGKAFARRLQGFD-ARIIY--HNRKRDLNA 183
>UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1;
Bordetella avium 197N|Rep: Putative reductase precursor
- Bordetella avium (strain 197N)
Length = 315
Score = 89.4 bits (212), Expect = 6e-17
Identities = 50/140 (35%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 199 GCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPA 378
G +ALV ++ + E+++A LK + + GY N E RG+Q++NTP+VL+
Sbjct: 46 GVTALVTSASTGASAELINAL-PDLKAICSWGVGYETINVEAAHRRGVQVSNTPDVLTDC 104
Query: 379 VAEVAVGLLLSASRRFTENLDQVRRGEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVK 555
VA++A GLL+SA+RR + VR G+W ++ LG + +G+IGLG IG+A+ +
Sbjct: 105 VADLAWGLLISAARRMGQGERFVRAGQWGQVHGSLPLGMRVSGKKLGVIGLGRIGEAIAR 164
Query: 556 RLSGFDVARFIYSGHREKPE 615
R +GFD+ Y R++ +
Sbjct: 165 RGAGFDM-EVRYHNRRQRTD 183
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 88.6 bits (210), Expect = 1e-16
Identities = 50/154 (32%), Positives = 86/154 (55%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L +EE+L+ I LV S +T ++++ A +LK++ G ++ + E +GI
Sbjct: 30 LTKEELLEKIKDADVLVVRSGTKVTRDVIEKA-EKLKVIGRAGVGVDNIDVEAATEKGII 88
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P+ S +VAE+ +GL+L+A+R + ++RGEW+ + G +L T+G+IG
Sbjct: 89 VVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWD--RKRFKGIELYGKTLGVIG 146
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
LG IGQ VVKR F + Y + K A+++
Sbjct: 147 LGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESM 180
>UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Porphyromonadaceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Porphyromonas gingivalis
(Bacteroides gingivalis)
Length = 319
Score = 87.8 bits (208), Expect = 2e-16
Identities = 60/180 (33%), Positives = 95/180 (52%), Gaps = 3/180 (1%)
Frame = +1
Query: 91 ALKILEDHFTVLQSRY-LNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGT 267
A + + F L +R+ + F +G +EEI + I C L + ++PI +++D G
Sbjct: 7 AFNTVSEGFDRLTARHEVVFPPKGRDFTQEEIAERIVDCDVLCSVFDIPIGRDLIDK-GR 65
Query: 268 QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQV 447
LK+++ + GYN+ + ++GI +TNTP + A++A+ LLLS +RR E
Sbjct: 66 SLKLIANYAVGYNNIDVTYAASKGIVVTNTPRAVIEPTADLALALLLSCTRRIAEWDRLF 125
Query: 448 RR-GEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
RR GE E G LG +L T+GIIG G IG AV +R F + +Y+ EA+
Sbjct: 126 RRDGEMVERGRLCRLGVNLYGKTLGIIGFGNIGAAVARRCKAFGM-NVLYNKRTRLSEAE 184
>UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase - Rhodobacterales bacterium
HTCC2654
Length = 301
Score = 87.8 bits (208), Expect = 2e-16
Identities = 53/137 (38%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Frame = +1
Query: 211 LVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEV 390
LV P+ + + L V T S G +H + L RGI L +TP+VLS +VAE+
Sbjct: 28 LVLSVETPLDSAAIARLPAGLAAVGTYSVGTDHIDRAALAERGIALLSTPDVLSASVAEI 87
Query: 391 AVGLLLSASRRFTENLDQVRRGEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQAVVKRLS 564
AV L L A RR TE++ VR G W G+ ++LG +L T GI G+G IG+ + RLS
Sbjct: 88 AVFLTLGAMRRATESISLVRSGAW-TGWTPGQLLGHELASRTAGIFGMGRIGREIAARLS 146
Query: 565 GFDVARFIYSGHREKPE 615
G + ++ R KP+
Sbjct: 147 GMGMTIAYHNRSRLKPK 163
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 87.4 bits (207), Expect = 2e-16
Identities = 58/167 (34%), Positives = 89/167 (53%), Gaps = 3/167 (1%)
Frame = +1
Query: 121 VLQSRYLNFGQEGSTL-GREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSA 297
+LQS+ + G L E+++ + L+ + + ++LD A LK+++ A
Sbjct: 18 LLQSQLVIDTYTGDNLISHAELIRRVADADFLIIPLSTQVDQDVLDHA-PHLKLIANFGA 76
Query: 298 GYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFD 477
G N+ + R I +TNTPNV + A AE VGL++S + R E D + R G+
Sbjct: 77 GTNNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVEG-DHLMRTSGFNGWA 135
Query: 478 KV--LGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKP 612
+ LG +L+ T+GI+GLG IGQAV KRL FD+ +YS H P
Sbjct: 136 PLFFLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMP-ILYSQHHRLP 181
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 87.0 bits (206), Expect = 3e-16
Identities = 46/131 (35%), Positives = 76/131 (58%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I EI+DAA LK + AGY++ + + R +GI +TNTP + AVA++A+GL+L+
Sbjct: 59 IDKEIIDAA-PNLKYIMKFGAGYDNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLAT 117
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYS 594
+R +++R G WE+ +G ++ +GIIG G IGQA+ +R +GF + Y
Sbjct: 118 ARNIPAKNEELRNGNWELS----MGIEIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYG 173
Query: 595 GHREKPEAKAL 627
+++ A L
Sbjct: 174 TFQDQTIADRL 184
>UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=8; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 335
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/127 (40%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +1
Query: 223 SNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGL 402
S+ IT +L A+ QLK++S+VS G ++ + L ARGI L +TP VL+ A+ L
Sbjct: 60 SSYAITASLL-ASAPQLKVISSVSVGVDNYDLPALAARGIMLCHTPGVLTETTADTIFSL 118
Query: 403 LLSASRRFTENLDQVRRGEW--EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFD 573
++++SRR E VR G W IG D + G D+ T+GI+G G IGQAV +R + GF+
Sbjct: 119 IMASSRRLVELASHVREGRWTRNIGED-LFGWDVHGKTLGILGFGRIGQAVARRAALGFN 177
Query: 574 VARFIYS 594
+ +S
Sbjct: 178 MPVLYHS 184
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 87.0 bits (206), Expect = 3e-16
Identities = 46/113 (40%), Positives = 69/113 (61%), Gaps = 1/113 (0%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+ V++ G NH + + R RG+ +TNTP V++ A A+ A+ LLL+A+RR E VR
Sbjct: 67 LRHVASYGVGVNHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVR 126
Query: 451 RGEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
G W E+ +LG ++ TVG++G G IGQA +R GFD R +Y+ R+
Sbjct: 127 AGGWTEVDPAWMLGTEVTGKTVGVVGFGRIGQAFARRARGFD-TRVLYTSPRD 178
>UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1;
Bdellovibrio bacteriovorus|Rep: Hxdroxypyruvate
reductase - Bdellovibrio bacteriovorus
Length = 319
Score = 86.6 bits (205), Expect = 4e-16
Identities = 50/148 (33%), Positives = 88/148 (59%), Gaps = 2/148 (1%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+++ K+ P +A+V + IT E++ A +KI++T S G++H + + RGI L+N
Sbjct: 39 DQVHKIQP--AAIVVVPRQKITAEVIKALPDSVKIIATSSVGFDHLDIAAAKERGILLSN 96
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDK--VLGQDLRDSTVGIIGL 528
TP+VL+ A++ + LLL+A RR E L ++ G W + + +LG + T+GI+G+
Sbjct: 97 TPDVLTECTADLGMMLLLNACRRGREYLSIMQEG-WRKTYSQTDMLGLQVSGRTLGILGM 155
Query: 529 GGIGQAVVKRLSGFDVARFIYSGHREKP 612
G IG+A+ R GF + + IY ++ P
Sbjct: 156 GRIGRALADRARGFGM-KIIYCNNKRLP 182
>UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 323
Score = 86.6 bits (205), Expect = 4e-16
Identities = 55/154 (35%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 124 LQSRY-LNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAG 300
L+ R+ L E + L I G L + IT E++ LK ++T+S G
Sbjct: 23 LRQRFDLEVNLEDTVLTPSGIASRAHGAEVLFVTATEAITAEVIRKLQPGLKTIATLSVG 82
Query: 301 YNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWE-IGFD 477
Y+H + R+ GI++ +TP+VLS A AE+A+ L+L+A RR E VR G W G
Sbjct: 83 YDHIDMAAARSLGIKVLHTPDVLSDACAEIAMLLVLNACRRGYEADRMVRSGSWPGWGPT 142
Query: 478 KVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVA 579
++LG L +GI G+G IG+A+ R GF +A
Sbjct: 143 QLLGMGLTGRRLGIFGMGRIGRAIATRARGFGLA 176
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 86.6 bits (205), Expect = 4e-16
Identities = 62/185 (33%), Positives = 99/185 (53%), Gaps = 3/185 (1%)
Frame = +1
Query: 82 PPTALKILE-DHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDA 258
P A++ILE D L+ +N G T R+E++ + + + I E+L+
Sbjct: 9 PREAMEILERDPHIELR---VNSEDRGCT--RDELVSGFQWADGALTMLSDKIDRELLEV 63
Query: 259 AGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENL 438
A +L++V+ + GYN+ + R + +TNTP+ L+ A A++ +GLLL+ +RR E
Sbjct: 64 A-PRLRVVANYAVGYNNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRLVEGD 122
Query: 439 DQVRRGEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKP 612
VR G ++ G+ + +LG DL T+GIIGLG IG V +R F + R +Y E P
Sbjct: 123 GLVRAGLFK-GWAPEFLLGMDLHGKTLGIIGLGEIGTCVARRARAFGM-RIVYCARHEAP 180
Query: 613 EAKAL 627
A L
Sbjct: 181 TASEL 185
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 85.8 bits (203), Expect = 8e-16
Identities = 44/113 (38%), Positives = 68/113 (60%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+I+S+ GY+ + E + G+++TNTP+VL+ VAEV + L+L+ + R E+ VR
Sbjct: 68 LEIISSFGVGYDAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYVR 127
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREK 609
G WE L +L +TVGIIGLG IG+A+ + F + R +Y G E+
Sbjct: 128 DGRWETEGAMPLTAELTGATVGIIGLGRIGKAIARLAQAFSM-RVVYHGRSEQ 179
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 85.8 bits (203), Expect = 8e-16
Identities = 47/134 (35%), Positives = 77/134 (57%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EEI + I ALV S +T EI+DA+ LK+++ G ++ + + +G+ + N
Sbjct: 33 EEIKQKIKDADALVVRSGTTVTKEIIDAS-ENLKVIARAGVGVDNVDLDAATEKGVVVVN 91
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
P+ S +VAE+ GL+LSA+R + +++GEW+ K G ++ T+GI+GLG
Sbjct: 92 APDASSISVAELMFGLMLSAARNIPQATASLKKGEWDRKSFK--GMEVYAKTLGIVGLGR 149
Query: 535 IGQAVVKRLSGFDV 576
IGQ V KR F++
Sbjct: 150 IGQQVAKRAQAFEM 163
>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Caldivirga
maquilingensis IC-167|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
maquilingensis IC-167
Length = 326
Score = 85.8 bits (203), Expect = 8e-16
Identities = 50/137 (36%), Positives = 78/137 (56%)
Frame = +1
Query: 202 CSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAV 381
C ALV + + +L A ++K+++T S GY+H + + RGI + TP VL AV
Sbjct: 52 CDALVVTIGDRVDDYVLSNA--KVKVIATYSVGYDHIDLDAATRRGIPVGYTPEVLVEAV 109
Query: 382 AEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRL 561
A++A+GL+++ +RR E VR GE + + LG ++ T+GI+GLG IG AV +R
Sbjct: 110 ADLAIGLIITLARRVIEGDRLVRSGEAYKVWGEFLGTEVWGKTLGILGLGNIGAAVARRA 169
Query: 562 SGFDVARFIYSGHREKP 612
F++ IY KP
Sbjct: 170 KAFNM-NVIYWSRTRKP 185
>UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia
aggregata IAM 12614|Rep: Glycerate dehydrogenase -
Stappia aggregata IAM 12614
Length = 319
Score = 85.4 bits (202), Expect = 1e-15
Identities = 44/126 (34%), Positives = 72/126 (57%), Gaps = 1/126 (0%)
Frame = +1
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
P+ E L A +IVS+ GY+H N ++ A + +T+TP+VL+ VA+ A+GL++
Sbjct: 55 PVNAEFL-AKVPNAEIVSSFGVGYDHINTDDCLAANVMVTHTPDVLTEEVADTALGLMIM 113
Query: 412 ASRRFTENLDQVRRGEWEI-GFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFI 588
R F + +R+G WE G K+ G ++ T+GI GLG IG+A+ KR F +
Sbjct: 114 TIREFGQAEQWLRQGNWESKGPYKLTGATMQGRTLGIFGLGRIGKAIAKRAEAFGMTIHY 173
Query: 589 YSGHRE 606
+ H++
Sbjct: 174 HGRHKQ 179
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 85.0 bits (201), Expect = 1e-15
Identities = 50/152 (32%), Positives = 85/152 (55%), Gaps = 1/152 (0%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
+ R+E+ + I A++ + P+ E++ G LK++ +AG+N+ + + + G+
Sbjct: 31 MDRQELSRQIATADAILTSLSDPLDAEMI-GQGKNLKVIGQCAAGFNNIDLDAAKQAGVV 89
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGE-WEIGFDKVLGQDLRDSTVGII 522
+T+TP VL A A++A LLL +RR E VR G W +LG L+ +T+GI+
Sbjct: 90 VTSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTFMLGAGLQGATLGIV 149
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHREKPEA 618
GLG IG+A+ +R + F + IY+ EK A
Sbjct: 150 GLGQIGEAMARRGAAFGM-NVIYNARHEKDVA 180
>UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillus
clausii KSM-K16|Rep: 2-ketogluconate reductase -
Bacillus clausii (strain KSM-K16)
Length = 321
Score = 85.0 bits (201), Expect = 1e-15
Identities = 51/170 (30%), Positives = 90/170 (52%), Gaps = 3/170 (1%)
Frame = +1
Query: 121 VLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAG 300
+ Q +L E L RE + + + ++ + E++ A ++LK++ST + G
Sbjct: 20 ISQFCHLRIWDESKPLTREALAHELADVDGAM-LTGIGADTELVKHA-SKLKVISTATVG 77
Query: 301 YNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEW--EIGF 474
Y+ + L + I +TNTP VL VA++ GL+LS +RR +QV+ G W +
Sbjct: 78 YDGFDVAGLAEQNIYVTNTPYVLDETVADLLFGLILSGARRIAPLHEQVKAGNWTKQTTA 137
Query: 475 DKVLGQDLRDSTVGIIGLGGIGQAVVKRL-SGFDVARFIYSGHREKPEAK 621
+ GQD+ + T+GI+G+G IG+ +V R GF + + +Y +PE +
Sbjct: 138 QSLYGQDVYNQTLGIVGMGRIGEKIVHRAKEGFGM-KILYHNRSSRPEVE 186
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 84.6 bits (200), Expect = 2e-15
Identities = 44/109 (40%), Positives = 68/109 (62%), Gaps = 1/109 (0%)
Frame = +1
Query: 280 VSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGE 459
++T S G +H + + +RARG+ + NTP +LS AVA+ A+ LLL+A+RR E +R G
Sbjct: 72 LATYSVGLDHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGR 131
Query: 460 W-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHR 603
W ++ +LG +L T+GI GLG IG+ V +R + F + R +Y R
Sbjct: 132 WTDLWSSHILGVELAGRTLGIYGLGDIGRRVARRATAFGM-RLVYHNRR 179
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 84.2 bits (199), Expect = 2e-15
Identities = 57/189 (30%), Positives = 96/189 (50%), Gaps = 1/189 (0%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDH-FTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNL 231
K+L+++ + A + LE F V+ S + S + ++ L+ G + + +
Sbjct: 35 KILITTRLFDDAATRFLEAQGFEVVPSGLPGDALD-SNIPDADLNALLEGAAGWI-VGQR 92
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
+T ++L AA QLK+++ GY+ + + R G +T PAVA+ + L+L+
Sbjct: 93 AVTRDVL-AAHPQLKVIARRGVGYDRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLA 151
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
RR + + RG+W + ++G DL TVG+IG G IG+ V +RLSGFDV +
Sbjct: 152 VLRRLKASQAAIARGDWRV----LVGADLTGKTVGLIGFGRIGRQVARRLSGFDVTVLVT 207
Query: 592 SGHREKPEA 618
S PEA
Sbjct: 208 S-RTPDPEA 215
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 84.2 bits (199), Expect = 2e-15
Identities = 52/143 (36%), Positives = 80/143 (55%), Gaps = 3/143 (2%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
REE+L + A++ E++ A G++LK++S AGY+ + + R I +
Sbjct: 13 REEVLHKVTDVDAIICHGKDKADAELV-AKGSKLKVISNFGAGYDTVDVKAATERNIWVC 71
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL---GQDLRDSTVGII 522
NTP ++ A A+VA+ LLL+A RR TE +R G WE +L G + T+GII
Sbjct: 72 NTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDILAFWGNNPEGKTLGII 131
Query: 523 GLGGIGQAVVKRLSGFDVARFIY 591
G+G IG+A+ KR + D+ R IY
Sbjct: 132 GMGNIGKALAKRAAALDM-RVIY 153
>UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1;
Bacillus subtilis|Rep: Probable 2-ketogluconate
reductase - Bacillus subtilis
Length = 325
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/128 (38%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I E+L+ A +LK+VS S GY++ + E ++ RG+ T+TP L VA++A L+LS+
Sbjct: 59 INRELLEHA-PKLKVVSNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSS 117
Query: 415 SRRFTENLDQ-VRRGEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDVARF 585
+RR E LD+ VR G+W + + + G D+ T+GIIG+G IG+ +R GFD+
Sbjct: 118 ARRVAE-LDRFVRAGKWGTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVL 176
Query: 586 IYSGHREK 609
++ HR++
Sbjct: 177 YHNRHRKQ 184
>UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus
Pelagibacter ubique|Rep: Probable dehydrogenase -
Pelagibacter ubique
Length = 317
Score = 83.8 bits (198), Expect = 3e-15
Identities = 39/128 (30%), Positives = 71/128 (55%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
+ ++++L G A++ + E + +K++S + G+ + + E + RGI +T
Sbjct: 35 QSKLIELSEGHDAILTSLTDKMDEETISKLPDSIKVISNFAVGFGNIDLEAAKKRGIAVT 94
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
NTP VLS A AE+ + L+L A RR E + + W+ D ++G+ L + +GI+G+G
Sbjct: 95 NTPEVLSDATAEIGILLILGACRRVPEGVQAAKESSWKWSADYLIGKQLTGTRLGILGMG 154
Query: 532 GIGQAVVK 555
IGQ + K
Sbjct: 155 RIGQKIAK 162
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 83.8 bits (198), Expect = 3e-15
Identities = 51/155 (32%), Positives = 88/155 (56%), Gaps = 3/155 (1%)
Frame = +1
Query: 154 EGSTLGREEILKL-IPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELR 330
EG+ + +E LK + AL+ + + + E++DAA LKI++ AG+N+ + + R
Sbjct: 29 EGTGIIDKETLKQGVKDADALISLLSTSVDKEVIDAANN-LKIITNYGAGFNNVDIDYAR 87
Query: 331 ARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL--GQDLRD 504
+ I +TNTP + + AE+ L+L+ +RR E D++ R G+ + G+++
Sbjct: 88 QQNIDVTNTPKASTNSTAELTFALVLAVARRIPEG-DKLCRTTGFDGWAPLFFRGREVSG 146
Query: 505 STVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREK 609
T+GIIGLG IG AV +R FD+ +Y+G +K
Sbjct: 147 KTIGIIGLGEIGSAVARRAKAFDM-NILYTGPHQK 180
>UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia phymatum STM815
Length = 321
Score = 83.8 bits (198), Expect = 3e-15
Identities = 49/124 (39%), Positives = 76/124 (61%), Gaps = 4/124 (3%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
A ++LK++STVS G++ + + L RGI LTNTP+VL+ + A+ A L+L +RR E
Sbjct: 58 ADASRLKVLSTVSVGFDAFDVDYLNKRGILLTNTPDVLTESTADTAFSLILLTARRLAEL 117
Query: 436 LDQVRRGEW--EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDV-ARFIYSGHR 603
V+ G+W +I D+ G D+ T+GI+GLG IG +V +R + GF + ++ G
Sbjct: 118 AAFVKAGKWTKKIAEDR-FGVDVHHKTLGIVGLGRIGTSVARRAALGFQMNVLYVDQGVN 176
Query: 604 EKPE 615
EK E
Sbjct: 177 EKAE 180
>UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75;
Proteobacteria|Rep: 2-ketogluconate reductase -
Escherichia coli O157:H7
Length = 324
Score = 83.8 bits (198), Expect = 3e-15
Identities = 62/183 (33%), Positives = 100/183 (54%), Gaps = 3/183 (1%)
Frame = +1
Query: 82 PPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAA 261
P L+ L++HFTV Q L+ T+ E+ + L+ SN + +L+
Sbjct: 12 PDDLLQRLQEHFTVHQVANLS----PQTV--EQNAAIFAEAEGLLG-SNENVDAALLEKM 64
Query: 262 GTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLD 441
+L+ ST+S GY++ + + L AR I L +TP VL+ VA+ + L+LS +RR E +
Sbjct: 65 -PKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAE 123
Query: 442 QVRRGEW--EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDVARFIYSGHREKP 612
+V+ GEW IG D G D+ T+GI+G+G IG A+ +R GF++ +Y+ R
Sbjct: 124 RVKAGEWTASIGPD-WYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMP-ILYNARRHHK 181
Query: 613 EAK 621
EA+
Sbjct: 182 EAE 184
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 83.4 bits (197), Expect = 4e-15
Identities = 46/129 (35%), Positives = 70/129 (54%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R + + + LV ++ + +E+L A +L++++ S GY++ + RGI
Sbjct: 37 RNLLYEWLADAEGLVSTGDVRVDDELL-AHAPRLRVIAQASVGYDNVDIAACTRRGIPFG 95
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
NTP VL A A++ GLLL A+RR E +QV G W D G DL T+GI+G+G
Sbjct: 96 NTPGVLVEATADLTFGLLLCAARRIHEGWNQVASGRWLNNHDVPFGIDLYGKTLGIVGMG 155
Query: 532 GIGQAVVKR 558
IG AV +R
Sbjct: 156 RIGAAVARR 164
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 83.0 bits (196), Expect = 5e-15
Identities = 45/137 (32%), Positives = 79/137 (57%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L + ++ ++P AL+ S +T E+L AAGT+L++V G ++ + E +GI
Sbjct: 30 LDKAGLIAILPEYDALIVRSATRVTAEVL-AAGTRLRVVGRAGTGVDNIDLEAATRQGIM 88
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P S AVAE+ + L+LS +R + V G+WE ++ +G ++R+ T+G++G
Sbjct: 89 VVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWE--RNRFMGFEVRNKTLGLVG 146
Query: 526 LGGIGQAVVKRLSGFDV 576
LG IG V +R G ++
Sbjct: 147 LGRIGAEVARRARGLEM 163
>UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15;
Pseudomonadales|Rep: 2-keto-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 321
Score = 82.6 bits (195), Expect = 7e-15
Identities = 51/128 (39%), Positives = 77/128 (60%), Gaps = 3/128 (2%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+ NE A LKIVSTVS GY++ + + L + I L +TP+VL+ A++A LL+SA
Sbjct: 55 LLNENNLAPAQHLKIVSTVSVGYDNYDVQYLNQKKIWLAHTPHVLTETTADLAFTLLVSA 114
Query: 415 SRRFTENLDQVRRGEWE--IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKR-LSGFDVARF 585
+R+ + + GEW+ +G + GQD+ T+GIIGLG IG A+ +R L GF++
Sbjct: 115 ARKVPQLDAWTKAGEWKRTVGAAQ-FGQDIFGKTLGIIGLGNIGAAIARRGLYGFNM-NI 172
Query: 586 IYSGHREK 609
+Y EK
Sbjct: 173 LYHNRHEK 180
>UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3;
Alphaproteobacteria|Rep: 2-hydroxyacid dehydrogenase -
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 311
Score = 82.2 bits (194), Expect = 9e-15
Identities = 47/121 (38%), Positives = 71/121 (58%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
AA L+IV+ G++ + E + RG +++NTP+VL+ VA++A+GL+L+ +R+ +
Sbjct: 62 AALPNLEIVAINGVGFDKVDLGEAKRRGFRVSNTPDVLTADVADLALGLVLAQARKVPQA 121
Query: 436 LDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
VR G+W G D L + GI GLG IGQA+ KRL GFD AR Y+ +
Sbjct: 122 DQHVRTGQWLKG-DMGLSTRVAGRRYGIFGLGRIGQAIAKRLEGFD-ARISYTARNRRDV 179
Query: 616 A 618
A
Sbjct: 180 A 180
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 82.2 bits (194), Expect = 9e-15
Identities = 52/147 (35%), Positives = 82/147 (55%), Gaps = 3/147 (2%)
Frame = +1
Query: 172 REEILKLIPG-CSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQL 348
R+E+ G C+A+V ++ + EILDAAG L++V+ V+ GY++ + A G+ +
Sbjct: 39 RDELAAGFTGACAAVVTLTER-VDAEILDAAGDGLRVVANVAVGYDNIDVAAAHAAGVTV 97
Query: 349 TNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR-RGEWEIGFDKVLGQDL-RDSTVGII 522
TNTP VL A A+ L+L+ +RR + +R R W G + G D+ +T+GI+
Sbjct: 98 TNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRMLTGLDVSAGATLGIL 157
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHR 603
G G IG+AV +R FD+ S R
Sbjct: 158 GYGRIGRAVARRARAFDMTVLATSRRR 184
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 82.2 bits (194), Expect = 9e-15
Identities = 51/181 (28%), Positives = 93/181 (51%)
Frame = +1
Query: 49 NLKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISN 228
NL+ ++ S+ P KIL+D + E L +EE++ + C L+ S
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVV--------EKQNLSKEELIAELQDCEGLIVRSA 56
Query: 229 LPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLL 408
+T ++++AA +L++V G ++ + E +GI + NTPN S + AE+ G+++
Sbjct: 57 TKVTADVINAA-EKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIM 115
Query: 409 SASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFI 588
+R+ + ++ G+WE K +G +L T+GI+GLG IG+ V R+ F +
Sbjct: 116 CLARQIPQATASMKDGKWE--RKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIG 173
Query: 589 Y 591
Y
Sbjct: 174 Y 174
>UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Paracoccus
denitrificans PD1222|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Paracoccus
denitrificans (strain Pd 1222)
Length = 314
Score = 81.8 bits (193), Expect = 1e-14
Identities = 45/115 (39%), Positives = 65/115 (56%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L++++ G + + E R RGI +T TP+VLS AVAE+A+GL L+A RR E VR
Sbjct: 59 LRLIAVNGVGVDAVDLAEARRRGIAVTTTPDVLSLAVAEMALGLALAAGRRIAEGDRFVR 118
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
G+W G LG L + GI+G G IG+ + L G + +Y+ EKP+
Sbjct: 119 AGQWSSGGKLGLGLSLLERRAGILGYGRIGRRLADLLRGMGM-EVLYTARHEKPD 172
>UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8;
Alphaproteobacteria|Rep: Glycolate reductase -
Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
Length = 323
Score = 81.4 bits (192), Expect = 2e-14
Identities = 43/121 (35%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Frame = +1
Query: 199 GCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPA 378
G A++ + +++A + I+++ S GY H + RGI +TNTP VLS A
Sbjct: 49 GAQAMLVTPTDRLERAVIEALPNSVAIIASFSVGYEHIDHNAAARRGILVTNTPGVLSDA 108
Query: 379 VAEVAVGLLLSASRRFTENLDQVRRGEWE-IGFDKVLGQDLRDSTVGIIGLGGIGQAVVK 555
A++A+ L+L A+RR +E VR G W+ + ++LG+ L +GI+G+G IGQA+ +
Sbjct: 109 TADIALLLMLGAARRASEGERLVRSGYWKGLTPVQLLGRHLHGQRLGILGMGRIGQALAE 168
Query: 556 R 558
R
Sbjct: 169 R 169
>UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:
T12C24.9 - Arabidopsis thaliana (Mouse-ear cress)
Length = 323
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/121 (40%), Positives = 63/121 (52%)
Frame = +1
Query: 208 ALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAE 387
A V LP+T+E+L + L+I+ S G +H + + RGI +TN N S VA+
Sbjct: 55 AFVISGRLPVTDELLSHLPS-LQILVCTSVGIDHIDLAACKRRGIVITNAGNAFSDDVAD 113
Query: 388 VAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSG 567
AVGLL+S RR VR G W D LG + VGI+GLG IG V KRL
Sbjct: 114 CAVGLLISVLRRIPAADRYVRSGNWAKFGDFQLGSKVSGKRVGIVGLGSIGSFVAKRLES 173
Query: 568 F 570
F
Sbjct: 174 F 174
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/151 (32%), Positives = 81/151 (53%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EEI + + A V S +T E+++ A LK+++ G ++ + + RGI + N
Sbjct: 33 EEIREHVRDADAWVVRSGTRVTRELIEEA-KNLKVIARAGVGVDNIDVKAATERGIIVVN 91
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
P S +VAE +GL+L+ +R+ + VRRGEW+ + +G +L T+G+IGLG
Sbjct: 92 APESSSISVAEHTMGLILALARKIPQADRSVRRGEWD--RKRFMGVELAGKTLGLIGLGR 149
Query: 535 IGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
IGQ V KR F++ Y + + A+ L
Sbjct: 150 IGQQVAKRAKAFEMEVTAYDPYIPEKVAEEL 180
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/130 (33%), Positives = 76/130 (58%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
+ +++++K+I + L++ L I +I+DA G LKI++ G ++ + E +GI
Sbjct: 30 ISKDDLIKIIKNYNILIFRGRLKIDKDIMDA-GQNLKILARYGVGLDNVDVEYAVKKGIA 88
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ + PN S +VAE+ +GLL S +RR +V+ GEW G K +G ++ T+GI+G
Sbjct: 89 VVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAGEWPKG--KYIGIEIAGKTMGIVG 146
Query: 526 LGGIGQAVVK 555
G IG+ V +
Sbjct: 147 FGRIGRFVAQ 156
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 81.0 bits (191), Expect = 2e-14
Identities = 47/154 (30%), Positives = 79/154 (51%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
+ REE+++ +P A+V S + E++ AA LKI+ G ++ + RGI
Sbjct: 30 MSREELIREVPKYEAIVVRSQTKVDAEVIQAA-KNLKIIGRAGVGVDNIDINAATQRGIV 88
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P + + AE A+ L+L+A+R+ + V+ G+WE K +G +LR T G+IG
Sbjct: 89 VVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGKWE--RKKFMGIELRGKTAGVIG 146
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
LG +G V KR ++ Y K A+ +
Sbjct: 147 LGRVGFEVAKRCKALEMNVLAYDPFVSKERAEQI 180
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 80.6 bits (190), Expect = 3e-14
Identities = 47/142 (33%), Positives = 78/142 (54%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L RE++L +I L+ S+ I E+++ A +LK+V G ++ + E RGI
Sbjct: 34 LEREKLLNIIENYDGLIIRSDTNIDIELMNMA-KKLKVVGRAGNGVDNIDIPEATKRGII 92
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ NTP+ + + E+ +GLLL+ SR + ++ G W+ D +G +L + T+GIIG
Sbjct: 93 VANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWD--RDSFMGTELFNKTLGIIG 150
Query: 526 LGGIGQAVVKRLSGFDVARFIY 591
LG IG V R++ FD+ Y
Sbjct: 151 LGRIGSLVATRMNAFDMKVIAY 172
>UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; marine gamma
proteobacterium HTCC2143|Rep: D-isomer specific
2-hydroxyacid dehydrogenase family protein - marine
gamma proteobacterium HTCC2143
Length = 312
Score = 80.6 bits (190), Expect = 3e-14
Identities = 45/115 (39%), Positives = 71/115 (61%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L++++++SAG+++ + EE R+RGI +TN P + S VA++AV LL S R ++ +
Sbjct: 67 LRMIASISAGFSNIDLEECRSRGIAVTNAPGMNSGDVADLAVTLLTSLLLRIPQSQSYIM 126
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
+W IG L LR+ VGI+GLG IG+ VV RL+ F + + G R KP+
Sbjct: 127 NDQW-IGKTPPLRHSLRNMPVGIVGLGSIGRDVVTRLTPFGL-NLKWWGPRPKPD 179
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 80.2 bits (189), Expect = 4e-14
Identities = 42/130 (32%), Positives = 78/130 (60%), Gaps = 1/130 (0%)
Frame = +1
Query: 172 REEILK-LIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQL 348
+ E+LK I G L+ S + E+++AA +LK+++ +G ++ + E + +GI++
Sbjct: 33 KPEVLKERIKGFDVLIVRSRTKVRREVIEAAD-KLKVIARAGSGLDNIDLEAAKEKGIKV 91
Query: 349 TNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGL 528
N P+ L AVAE+ +G+++ +RR + ++ GEWE KV+G +L T+G++G
Sbjct: 92 VNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLEGEWE----KVMGFELAGKTLGVVGF 147
Query: 529 GGIGQAVVKR 558
G IG+ V K+
Sbjct: 148 GRIGREVAKK 157
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 80.2 bits (189), Expect = 4e-14
Identities = 50/154 (32%), Positives = 82/154 (53%), Gaps = 1/154 (0%)
Frame = +1
Query: 154 EGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRA 333
+GST +E++ L G L+ + PIT + +A L++VS + G ++ + E A
Sbjct: 31 DGSTRSVDELIALADGADVLLSVLADPITEALFEAR-PGLQMVSQYAVGVDNIDLEAAEA 89
Query: 334 RGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWE-IGFDKVLGQDLRDST 510
+ +T+TP VL+ A A+ A LLL+A+R VR G +E ++G +L T
Sbjct: 90 HDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTHLMGMELARKT 149
Query: 511 VGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKP 612
+GI+G+G IG AV +R GF + ++ R P
Sbjct: 150 IGIVGMGRIGTAVARRALGFGMEVIYHNRTRANP 183
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 80.2 bits (189), Expect = 4e-14
Identities = 47/125 (37%), Positives = 71/125 (56%), Gaps = 2/125 (1%)
Frame = +1
Query: 193 IPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLS 372
+ AL+ + + P+T LD L+++ T S G NH ++RGI++ NT VL+
Sbjct: 57 LASAEALIVLLSEPLTEADLDLC-PNLRVIGTYSVGINHLPITSCQSRGIRIVNTQGVLT 115
Query: 373 PAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQA 546
A A++A+ LLLS +RR E VR G W+ G+ D +LG L T GI+G G IG+A
Sbjct: 116 DATADLALTLLLSLTRRVREGEALVRSGHWK-GWAPDLLLGTGLTGKTCGILGSGPIGRA 174
Query: 547 VVKRL 561
+R+
Sbjct: 175 FARRV 179
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 79.8 bits (188), Expect = 5e-14
Identities = 46/135 (34%), Positives = 77/135 (57%), Gaps = 1/135 (0%)
Frame = +1
Query: 211 LVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEV 390
L+ + P+ +LDA +L++VS ++ G+++ + AR I++ NTP VL+ A A++
Sbjct: 55 LLTLLTRPVDAALLDAF-PELRVVSNMAVGFDNVDVPACTARSIRVGNTPGVLTDATADL 113
Query: 391 AVGLLLSASRRFTENLDQVRRGEWEIGFDK-VLGQDLRDSTVGIIGLGGIGQAVVKRLSG 567
A+ LLLSA+R R G W+ LG +LR +T+G++GLG IG AV +R
Sbjct: 114 AMALLLSAARNLPAASLDAREGRWQTWSPTGWLGLELRGATLGVVGLGKIGLAVAQRARA 173
Query: 568 FDVARFIYSGHREKP 612
F + +Y+ + P
Sbjct: 174 FGM-DILYTRRSDAP 187
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 79.0 bits (186), Expect = 9e-14
Identities = 45/144 (31%), Positives = 77/144 (53%)
Frame = +1
Query: 160 STLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARG 339
+ + REE+L++I A++ S + E+++ G +LK++ G ++ + E RG
Sbjct: 27 TNISREELLEVIKDYDAIIVRSATKVDRELIEK-GEKLKVIGRAGNGVDNIDVEAATQRG 85
Query: 340 IQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGI 519
I + NTP + A AE+ +GL+L+ +R + G++ D+ G +L TVGI
Sbjct: 86 ILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAALNGDFR--RDRFKGVELNGKTVGI 143
Query: 520 IGLGGIGQAVVKRLSGFDVARFIY 591
IGLG IG V RL+ F++ Y
Sbjct: 144 IGLGRIGSLVASRLAAFNMRVIAY 167
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 79.0 bits (186), Expect = 9e-14
Identities = 44/130 (33%), Positives = 71/130 (54%), Gaps = 3/130 (2%)
Frame = +1
Query: 241 NEILDAAGTQL---KIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
NEI DA QL KI++ G ++ + + + G+ +TN PN AVA+ A LLLS
Sbjct: 55 NEIHDAVLAQLPDLKIIAKHGVGVDNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLS 114
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+R+ ++ ++G+W + G D+ T+GIIGLG IG+ V +R SGF + Y
Sbjct: 115 LARQIPTGNEKTKKGKW----PSLFGADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAY 170
Query: 592 SGHREKPEAK 621
+ ++ A+
Sbjct: 171 DPYIDRTYAR 180
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 79.0 bits (186), Expect = 9e-14
Identities = 57/172 (33%), Positives = 84/172 (48%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
KVLVS N P ++ILE Q + F + L REE L +I L+ S
Sbjct: 3 KVLVSDN-ISPKGIEILE------QEADVTFNPD---LSREEFLDIIGEYDGLIVRSMTE 52
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+ E LD A LK++ GY++ + EE RGI + NTP + + E +G++L+
Sbjct: 53 VDKEALDKA-RNLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLAL 111
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
SR + + G W+ K +G +++ T+GIIGLG IG V R F
Sbjct: 112 SRNIPQANQALHEGIWD--RKKYMGVEVKGKTLGIIGLGRIGSRVAVRAQAF 161
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 79.0 bits (186), Expect = 9e-14
Identities = 47/144 (32%), Positives = 75/144 (52%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R + L I + + I E++DA GT+LK ++ AG ++ + R I L
Sbjct: 35 RAQTLAAIADYDGIAVRTKFRIDRELIDA-GTKLKFIARAGAGLDNIDEAVALERNIHLI 93
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
N P AV E AVGL+LS F ++R+G+W+ ++ G +L+ TVGIIG G
Sbjct: 94 NAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKGKWDREGNR--GYELKGKTVGIIGYG 151
Query: 532 GIGQAVVKRLSGFDVARFIYSGHR 603
+G ++ ++LSGF V Y ++
Sbjct: 152 FMGSSLARKLSGFGVQVIAYDKYK 175
>UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 333
Score = 79.0 bits (186), Expect = 9e-14
Identities = 54/165 (32%), Positives = 86/165 (52%), Gaps = 2/165 (1%)
Frame = +1
Query: 82 PPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAA 261
P T L+ L+ F L EG + +I + A++ PI+ +++ +
Sbjct: 24 PTTVLEALKQQFE------LQVWDEGP-MPTAQIAQWAKTTDAILCSLGTPISADLI-RS 75
Query: 262 GTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLD 441
QL +S++S G +H + A + + +TP+VL + A++A+ L+L+A+RR E
Sbjct: 76 NPQLSTISSISVGVDHIDMAAATAASLPVGHTPDVLVDSTADLALALMLAATRRVVEADR 135
Query: 442 QVRRGEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
VR G W + D LG DL +TVGI+GLG G AVVKR+ F
Sbjct: 136 FVRGGHWSADWATDFFLGTDLSRATVGIVGLGPTGLAVVKRVRAF 180
>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
Brucella melitensis
Length = 360
Score = 78.6 bits (185), Expect = 1e-13
Identities = 47/156 (30%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
+ + EI+ + LV I +++ AG LK+++ G ++ + RGI
Sbjct: 64 MSQPEIIAALKEADVLVPCITDVIDAAVIEQAGPNLKLIANFGNGVDNIDVAAAARRGIT 123
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTE--NLDQVRRGEWEIGFDK--VLGQDLRDSTV 513
+TNTPNVL+ A++ + LLLS RR E N+ R G+W G+ +LG+ + +
Sbjct: 124 VTNTPNVLTEDTADMTLALLLSVPRRLVEGANVINERHGQWP-GWSPTWMLGRRIWGKRL 182
Query: 514 GIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
GI+G+G IG AV +R F ++ ++ R P+ +
Sbjct: 183 GIVGMGRIGTAVARRAKAFGLSIHYHNRKRVSPQVE 218
>UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=16; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Silicibacter pomeroyi
Length = 330
Score = 78.6 bits (185), Expect = 1e-13
Identities = 38/107 (35%), Positives = 65/107 (60%), Gaps = 2/107 (1%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E LD Q ++++ GY+H + + +RA GI ++NTP+VLS A++A+ L+L +RR
Sbjct: 68 EALDVTAPQTRLLANYGVGYSHIDSDAVRAHGITVSNTPDVLSECTADIAMTLMLMVARR 127
Query: 424 FTENLDQVRRGEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
E ++R G+W G+ ++G + +GI+G G IGQA+ +R
Sbjct: 128 AGEGERELRAGQW-TGWRPTHLVGSKVSGKVLGIVGFGRIGQAMAQR 173
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 78.6 bits (185), Expect = 1e-13
Identities = 46/125 (36%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
Frame = +1
Query: 205 SALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVA 384
++ V I +I+DA LK+++ GY+ + + RGI + NTP LS +VA
Sbjct: 44 ASAVLIGTQKFDADIMDAM-PNLKVIARNGVGYDAVDVDAATQRGIYVVNTPKALSGSVA 102
Query: 385 EVAVGLLLSASRRFTENLDQVRRGEWEIGFDKV-LGQDLRDSTVGIIGLGGIGQAVVKRL 561
E AV LL+ S+ ++ + W + K G+D+ TVGI+G G IGQ V K+L
Sbjct: 103 ETAVSELLAISKNLYQDSKAIHDDNW--NYRKAHPGRDIEGKTVGILGFGRIGQQVAKKL 160
Query: 562 SGFDV 576
SGFDV
Sbjct: 161 SGFDV 165
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/142 (34%), Positives = 76/142 (53%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L +E+++LI G ALV + +T +++ A LKI++ GYN + A GI
Sbjct: 37 LTEDELVELIKGMDALVAGMDA-VTAKVIAAGLPTLKIIAKHGVGYNTIDVAAAAAYGIP 95
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+T TP + +VAE+A+GL+L+ +R + VRRG W ++ G +L +GIIG
Sbjct: 96 VTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGW----SRMTGSELYGKVLGIIG 151
Query: 526 LGGIGQAVVKRLSGFDVARFIY 591
+G IG V KR F + Y
Sbjct: 152 MGSIGCEVAKRAHAFGMKIIAY 173
>UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1;
Colwellia psychrerythraea 34H|Rep: Putative glyoxylate
reductase - Colwellia psychrerythraea (strain 34H / ATCC
BAA-681) (Vibriopsychroerythus)
Length = 311
Score = 78.2 bits (184), Expect = 2e-13
Identities = 43/118 (36%), Positives = 71/118 (60%), Gaps = 1/118 (0%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
+K+++ + GY++ + A+GI +TNTP V++ A++A L+L+ASR+ T N +R
Sbjct: 61 IKLIANIGVGYDNIDLAAATAKGIAVTNTP-VVTEDTADLAFSLILAASRQLTANEKFLR 119
Query: 451 RGEWEIGFD-KVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
G+W LG+ + + +GIIG G IGQAV +R F++ F Y G R K +A+
Sbjct: 120 NGQWSATNPIGCLGKTVHGAKLGIIGFGEIGQAVARRAKAFNMEIF-YHGPRRKIDAE 176
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 77.8 bits (183), Expect = 2e-13
Identities = 47/150 (31%), Positives = 77/150 (51%)
Frame = +1
Query: 178 EILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNT 357
E+LK + ++ ++N+P+ E+++AA T LK++S G +H N E R I + N+
Sbjct: 81 EVLKKRVETADVLILANMPLKKEVIEAA-TNLKMISVAFTGIDHINMETCRKNNIMVCNS 139
Query: 358 PNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGI 537
+ +V E+ GL+LS R D+VR G + G+ + DL T+G+IG G I
Sbjct: 140 AGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQGYSQ---YDLAGKTLGVIGAGDI 196
Query: 538 GQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G V++ F +Y+ EK K L
Sbjct: 197 GTEVIRIGKAFGCNVLVYN-RSEKQHIKEL 225
>UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia cepacia (strain ATCC 53795 /
AMMD)
Length = 320
Score = 77.8 bits (183), Expect = 2e-13
Identities = 42/125 (33%), Positives = 71/125 (56%), Gaps = 2/125 (1%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E + A +KI++ SAGY+H + R RGI ++N P+ L+ A+ + L+L+A RR
Sbjct: 64 EHIAALPPSVKIIANASAGYDHLDVAAARERGIVVSNAPDALTDCTADFTMLLMLAACRR 123
Query: 424 FTENLDQVRRGEW--EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSG 597
+E +++ R W G +LG + T+GI+G G IG+AV +R GF + + +Y+
Sbjct: 124 ASE-YERIVRAGWGKSFGMTDMLGTRVNGKTLGIVGFGRIGRAVAQRARGFGM-KIVYTD 181
Query: 598 HREKP 612
+ P
Sbjct: 182 RQPAP 186
>UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: 2-hydroxyacid
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 335
Score = 77.8 bits (183), Expect = 2e-13
Identities = 43/120 (35%), Positives = 65/120 (54%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E+++ +K + AGY+ + ARGIQ+++TP + A A V L +SA R+
Sbjct: 76 ELINKLPASVKYICHNGAGYDQIDVAACTARGIQVSHTPQAVDDATATVGAFLAISAMRQ 135
Query: 424 FTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHR 603
F VR G+W+ G +D T+GIIG+GGIG A+ +RL FD+ + IY R
Sbjct: 136 FWRAEVNVRSGKWKAGLSP--ARDPEGKTLGIIGMGGIGSALARRLLAFDM-KVIYYNRR 192
>UniRef50_Q89Y67 Cluster: Oxidoreductase; n=14;
Alphaproteobacteria|Rep: Oxidoreductase - Bradyrhizobium
japonicum
Length = 329
Score = 77.4 bits (182), Expect = 3e-13
Identities = 39/98 (39%), Positives = 61/98 (62%)
Frame = +1
Query: 268 QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQV 447
++++V++ GY+H + + I +TNTP+VL+ VA+VA+GLL+S R F + V
Sbjct: 75 KIEMVASFGVGYDHVDAKYAAEHNIIVTNTPDVLTEEVADVAMGLLISTVREFIKADRYV 134
Query: 448 RRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRL 561
R G W+ + LRD VGI+G+G IGQA+ +RL
Sbjct: 135 RSGLWQTQNYPLSVGSLRDRKVGIVGMGRIGQAIARRL 172
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 2/153 (1%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE+L++IP AL+ S +T E+L A GT+LK+V G ++ + RG+ + N
Sbjct: 31 EELLEIIPEYDALITRSETKVTAEVL-ARGTRLKVVGRAGVGVDNIDVAAATERGVVVVN 89
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTE-NLDQVRRGEWE-IGFDKVLGQDLRDSTVGIIGL 528
P + + AE A GLL++ +R + + R G W+ + F +G +L T+GIIGL
Sbjct: 90 VPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSF---VGTELHGKTLGIIGL 146
Query: 529 GGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G IG V R F + Y + A+ L
Sbjct: 147 GRIGSEVAVRARAFGMRVLAYDPYVPHSRAEHL 179
>UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 317
Score = 77.4 bits (182), Expect = 3e-13
Identities = 46/112 (41%), Positives = 62/112 (55%)
Frame = +1
Query: 241 NEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASR 420
N L AA +L+I+S G + + R RGI++TNTP+VL+ VA++ VGL L+ R
Sbjct: 62 NAELIAALPKLEIISCYGVGTDAIDLAAARERGIRVTNTPDVLTGDVADLGVGLALAMMR 121
Query: 421 RFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
VR G W G D L L VG++G G IG + +RLSGFDV
Sbjct: 122 HIGAGDAYVRSGAWSDG-DMPLVTRLYGKRVGVVGFGRIGTTIARRLSGFDV 172
>UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2;
Filobasidiella neoformans|Rep: Glyoxylate reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 345
Score = 77.4 bits (182), Expect = 3e-13
Identities = 43/119 (36%), Positives = 67/119 (56%), Gaps = 7/119 (5%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+ E++ A L+ +S+ S GY+H + + ARGI++ +TP VLS AVA++AV L+LS
Sbjct: 62 VDKELIATANDNLRCISSFSVGYDHIDVKAANARGIKIGHTPGVLSDAVADIAVILVLST 121
Query: 415 SRRFTENLDQVRRGEWE-------IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
RR E ++ V+ G W+ + +G T+G +G G I QA V+RL F
Sbjct: 122 LRRIGEGINLVKSGNWKQQPWAPFVNCGLSIGHP--SLTIGFLGFGRISQATVQRLLAF 178
>UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n=4;
Trichocomaceae|Rep: Glyoxylate/hydroxypyruvate reductase
- Aspergillus oryzae
Length = 350
Score = 77.4 bits (182), Expect = 3e-13
Identities = 42/120 (35%), Positives = 68/120 (56%)
Frame = +1
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
P E++ + LK + AGY+ + + RGI+++NTP V++ A A+VA+ L+L
Sbjct: 76 PFDKELIHSLPLTLKFICLNGAGYDGMDIQTCTERGIRISNTPKVVADATADVAMFLMLG 135
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
A R+ L +R G+W+ D LG+D +GI+G+G IGQA+ R F + + IY
Sbjct: 136 ALRQAMIPLVSIRNGQWK--GDTPLGRDPGGKVLGILGMGAIGQAIAHRARAFGL-KIIY 192
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 77.4 bits (182), Expect = 3e-13
Identities = 45/134 (33%), Positives = 73/134 (54%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L +E+L++IP ALV S +T +L AA QLK+V+ G ++ + EE GI
Sbjct: 37 LDADELLQIIPEYEALVVRSETKVTGNLLRAA-KQLKVVARAGVGVDNVDVEEATKLGIV 95
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N+P+ A AE + LL++ +R E ++ G+WE K +G +++ T+ IIG
Sbjct: 96 VVNSPSGNIGAAAEHTIALLIAMARNIPEACSSLKSGKWE--RSKFVGVEVKGKTLSIIG 153
Query: 526 LGGIGQAVVKRLSG 567
LG +G V + G
Sbjct: 154 LGKVGLTVARLAKG 167
>UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase
UNK4.10; n=14; Dikarya|Rep: Putative 2-hydroxyacid
dehydrogenase UNK4.10 - Schizosaccharomyces pombe
(Fission yeast)
Length = 334
Score = 77.4 bits (182), Expect = 3e-13
Identities = 40/127 (31%), Positives = 65/127 (51%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
EI+D +K + + AGY + ARGIQ+++ P + A A+V + L+L A R
Sbjct: 72 EIIDNLPPSVKFICHLGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGALRG 131
Query: 424 FTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHR 603
F + + ++ + W D T+GI+GLGGIG+ + KR FD+ + +Y
Sbjct: 132 FNQGIFELHKNNWNANCKP--SHDPEGKTLGILGLGGIGKTMAKRARAFDM-KIVYHNRT 188
Query: 604 EKPEAKA 624
PE +A
Sbjct: 189 PLPEEEA 195
>UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n=1;
Gluconobacter oxydans|Rep: Putative 2-hydroxyacid
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 310
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/148 (31%), Positives = 74/148 (50%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E + + P + + +EI+DA L+++S G + N +E R R I +
Sbjct: 34 ENLKNIAPAIRGITTGGGSGVPSEIMDAL-PNLEVISVNGVGTDRINLDEARRRNIGVAI 92
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
T N L+ VA++AV L+++ R N VR G+W LG+ L VGI G G
Sbjct: 93 TQNTLTDDVADMAVALMMAVMRSIVTNDAFVRAGKWPSA-TAPLGRSLTRKKVGIAGFGH 151
Query: 535 IGQAVVKRLSGFDVARFIYSGHREKPEA 618
IGQA+ KR+S F + ++ H +PE+
Sbjct: 152 IGQAIAKRVSAFGMEVAYFNSH-ARPES 178
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 76.6 bits (180), Expect = 5e-13
Identities = 43/127 (33%), Positives = 70/127 (55%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E + LI C ALV+ S + ++ +++ A +LK++ +G ++ + E R RG+QL
Sbjct: 55 ESLHALIRDCEALVFRSGIRVSADLMGCA-PRLKLLVRAGSGMDNLDVEYARKRGVQLVR 113
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
P + AVAE+A +L+ SRR E +R G WE + G LRD T+G++G+G
Sbjct: 114 IPQPSARAVAEMAFAFMLALSRRLLEADRSMRNGRWE--KHEFSGYLLRDKTLGVVGIGN 171
Query: 535 IGQAVVK 555
G V +
Sbjct: 172 TGSCVAQ 178
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 76.6 bits (180), Expect = 5e-13
Identities = 43/140 (30%), Positives = 73/140 (52%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
REE+LK+I L+ S + EI+ G LKI++ G ++ + EE R I++
Sbjct: 49 REELLKIIDQYQVLIVRSRTKVDKEII-RYGVNLKIIARAGIGLDNIDTEEASKRNIKIV 107
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
P + + AE+ +GLL++A+R+ ++++ + G F K+ G +L T+GI+G G
Sbjct: 108 YAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGI----FKKIEGIELAGKTIGIVGFG 163
Query: 532 GIGQAVVKRLSGFDVARFIY 591
IG V K D+ Y
Sbjct: 164 RIGTKVAKVCKALDMNVIAY 183
>UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Methanococcoides burtonii (strain DSM
6242)
Length = 317
Score = 76.6 bits (180), Expect = 5e-13
Identities = 45/114 (39%), Positives = 67/114 (58%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
IT E++ A LK++S V G + N E GI++T TP+ + AVAE+ VG++L
Sbjct: 59 ITEEVIKNA-PNLKLISRVGVGLDGVNFELCNKYGIKVTYTPDAPTMAVAELCVGIILDL 117
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
SR+ + VR+G W D+ +G L TVGI G+G IG+++V LS F+V
Sbjct: 118 SRKISYTDRNVRKGVW----DRYMGNLLYGKTVGIFGMGRIGKSLVHLLSSFNV 167
>UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Congregibacter
litoralis KT71|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Congregibacter litoralis
KT71
Length = 316
Score = 76.2 bits (179), Expect = 6e-13
Identities = 46/141 (32%), Positives = 79/141 (56%), Gaps = 2/141 (1%)
Frame = +1
Query: 208 ALVWISNL--PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAV 381
A VW+ P++ E++ + L +++ + G ++ + + RGI ++NTP V++
Sbjct: 43 ATVWLGTAVDPVSRELIASFPDSLGLIANLGVGTDNVDLVAAKERGILVSNTP-VVTEDT 101
Query: 382 AEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRL 561
A++ LLL+ RR E +R G+W G ++G+ + + +GIIG G IGQAV +R
Sbjct: 102 ADLTFALLLATCRRVGECERALRGGDWA-GGAALMGRRVHGAKLGIIGFGAIGQAVAQRA 160
Query: 562 SGFDVARFIYSGHREKPEAKA 624
GFD+ Y G R K +A+A
Sbjct: 161 RGFDM-DVGYHGPRRKADAEA 180
>UniRef50_Q54DP1 Cluster: Gluconate 2-dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Gluconate
2-dehydrogenase - Dictyostelium discoideum AX4
Length = 334
Score = 76.2 bits (179), Expect = 6e-13
Identities = 42/113 (37%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+ VS +S GY++ + L R I L +TPNVL+ ++A++ +GL+++ +R+ ++R
Sbjct: 76 LECVSAISVGYDNYDLVVLNDRKIPLMHTPNVLNDSMADIMMGLMITVARKLAYCDKRMR 135
Query: 451 RGEWEIGFDKV-LGQDLRDSTVGIIGLGGIGQAVVKRL-SGFDVARFIYSGHR 603
GEW DK G ++ VGIIG+G IG+ + KR GFD+ YS R
Sbjct: 136 NGEWNGPLDKSWFGLEVHHKKVGIIGMGRIGEVLAKRCRMGFDMEVAYYSRSR 188
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 76.2 bits (179), Expect = 6e-13
Identities = 51/176 (28%), Positives = 92/176 (52%)
Frame = +1
Query: 49 NLKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISN 228
++KVLVS + L+IL++HF + + L +E+++ I G ALV S
Sbjct: 17 DMKVLVSDS-LSNEGLEILKEHFDI---------DVCTGLCEDELVEKIKGYDALVIRSG 66
Query: 229 LPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLL 408
+T I++AA LKI+ G ++ + + +GI + N P + AE + +++
Sbjct: 67 TQVTQRIIEAADN-LKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMM 125
Query: 409 SASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
S SR + ++ EW+ +K +G +++ T+G+IGLG IG V KR +G ++
Sbjct: 126 SMSRNIPQANASLKAREWKR--NKFMGVEVKGKTLGVIGLGRIGSEVAKRAAGLEM 179
>UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Rep:
Im:7137941 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 337
Score = 75.8 bits (178), Expect = 8e-13
Identities = 38/133 (28%), Positives = 74/133 (55%)
Frame = +1
Query: 217 WISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAV 396
W N+ + ++L + LK V G +H + + + G++++NTP+V+ A A++ +
Sbjct: 67 WGPNINVDRDLLQSL-PNLKAVINGGVGVDHLDIPLINSFGVKVSNTPHVVDNATADIGM 125
Query: 397 GLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
L+L+++R+ E + E + + +G D+ +T+GIIG+G IG + KR GFD+
Sbjct: 126 SLMLASARKIIEGQHFSKFRESDDFPESTMGTDVSGATLGIIGMGRIGYKIAKRAQGFDM 185
Query: 577 ARFIYSGHREKPE 615
+ +Y +PE
Sbjct: 186 -KILYHNRNRRPE 197
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 75.4 bits (177), Expect = 1e-12
Identities = 46/142 (32%), Positives = 78/142 (54%)
Frame = +1
Query: 151 QEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELR 330
++G L EE++++I GC+ ++ + + P+ ++L+ +LK ++ ++ + E +
Sbjct: 32 EQGYHLTDEELIQIIDGCAGII-VGSEPLPKKVLET-NPRLKTIACCGKHLDNIDVEYAQ 89
Query: 331 ARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDST 510
+ I + N P + AVAE VGL+LS R+ +VR G W K +G L
Sbjct: 90 EKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWH----KRIGNLLHGKR 145
Query: 511 VGIIGLGGIGQAVVKRLSGFDV 576
VGIIGLG +G+AV +RL F V
Sbjct: 146 VGIIGLGQVGKAVAERLLPFGV 167
>UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16;
Bacteria|Rep: Phosphonate dehydrogenase - Pseudomonas
stutzeri (Pseudomonas perfectomarina)
Length = 336
Score = 75.4 bits (177), Expect = 1e-12
Identities = 46/140 (32%), Positives = 75/140 (53%)
Frame = +1
Query: 151 QEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELR 330
Q STL REEIL+ A++ + + L A +L++V G+++ + +
Sbjct: 29 QTDSTLTREEILRRCRDAQAMMAFMPDRVDADFLQAC-PELRVVGCALKGFDNFDVDACT 87
Query: 331 ARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDST 510
ARG+ LT P++L+ AE+A+GL + R VR GE++ + G L ++T
Sbjct: 88 ARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQPQFYGTGLDNAT 147
Query: 511 VGIIGLGGIGQAVVKRLSGF 570
VGI+G+G IG A+ RL G+
Sbjct: 148 VGILGMGAIGLAMADRLQGW 167
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/153 (29%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R+ +LK I ++ ++ + EI+DAA LK++ST G++H + + R +GI +T
Sbjct: 39 RQWVLKNIAKYDGVI-VAKMIFDKEIIDAA-KNLKVISTYGVGFDHIDIDYAREKGIVVT 96
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKV--LGQDLRDSTVGIIG 525
N PN + AE+A+ ++++++RR +R G + + D+ G + T+GI+G
Sbjct: 97 NCPNSVLRPTAELALTMIMASARRIRYYDHALREGVF-LNVDEYDSQGYTIEGKTLGILG 155
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
+G IGQ V + + ++ H+ KPE +A
Sbjct: 156 MGRIGQQVARFAKALGMKIIYHNRHQLKPELEA 188
>UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
glyoxylate reductase - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 315
Score = 74.9 bits (176), Expect = 1e-12
Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 2/162 (1%)
Frame = +1
Query: 79 YP--PTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEIL 252
YP P + +LE+ +T L L G+E L + + P SALV ++ I +L
Sbjct: 9 YPLRPHQMAMLEETYT-LHRLDLVKGEERDAL----LQQAGPISSALVCNGHVTIDEALL 63
Query: 253 DAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTE 432
LK+ + SAGY+ + E + RGI+LTNT VL VA++A+ L+L+A RR E
Sbjct: 64 SKLPA-LKLAACSSAGYDQMDLEAMTRRGIKLTNTSEVLCDDVADMALLLMLAARRRLPE 122
Query: 433 NLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
VR G+W L GI+GLG IG A+ KR
Sbjct: 123 GDRYVRSGDWGQKGMMPLTTSTSGKKAGIVGLGRIGMAIAKR 164
>UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=24; Rhodobacterales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Silicibacter sp. (strain TM1040)
Length = 322
Score = 74.9 bits (176), Expect = 1e-12
Identities = 35/97 (36%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
Frame = +1
Query: 274 KIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRR 453
++++ G+NH + E RA G+++TNTP ++ A A++A+ L+L +RR E VR
Sbjct: 75 RLLANFGVGFNHIDAEAARAAGVEVTNTPGAVTDATADIALTLMLMTARRAGEGERLVRS 134
Query: 454 GEWEIGF--DKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
G+W+ G+ ++LG L +G++GLG IG A+ +R
Sbjct: 135 GQWQ-GWHPTQMLGLHLSGKRLGVVGLGRIGDAIARR 170
>UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 387
Score = 74.9 bits (176), Expect = 1e-12
Identities = 41/130 (31%), Positives = 66/130 (50%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I E+L A L+ + AGY+ + A G++++NTP+ + A A+ + L+L A
Sbjct: 91 IDAELLAALPPTLRFICHNGAGYDQIDVAACTAAGVRVSNTPSAVDDATADAGIFLMLGA 150
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYS 594
R F + R GEW LG D R +GI+G+GGIG+ + K+ + F + Y+
Sbjct: 151 LRNFGPGMQSCRNGEWIGKPAPALGHDPRGKVLGILGMGGIGRNMAKKAAVFGMKIRYYN 210
Query: 595 GHREKPEAKA 624
R E +A
Sbjct: 211 RTRLSAELEA 220
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 74.5 bits (175), Expect = 2e-12
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Frame = +1
Query: 55 KVLVSSN----DYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWI 222
K++VS++ D+ P ++ FT+ + Y L +EI+ L+ + +
Sbjct: 3 KIVVSTSSFGFDHNPAIQQLRAQGFTITGNPYQR------KLTEDEIITLLGNDTVALLA 56
Query: 223 SNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGL 402
P+T +L +A L++++ G ++ + E R IQ++NTP + AVAE+ +GL
Sbjct: 57 GVEPLTEHVLTSASA-LRVIARCGTGMDNVDLEAARRLNIQVSNTPEAPAQAVAELTLGL 115
Query: 403 LLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVAR 582
+L R+ VR+GEW + G+ L TVGI+GLG IG+ V K F
Sbjct: 116 MLDCLRQINRIDRSVRQGEW----PRSQGRLLAARTVGIVGLGHIGRRVAKLCQAFGAQV 171
Query: 583 FIYSGH 600
+ H
Sbjct: 172 IAHDPH 177
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/127 (35%), Positives = 68/127 (53%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E +++ + A++ +L + E LDAA LKI+S +G N ARG+ +TN
Sbjct: 34 EAVIREVGDADAVI-TRDLGFSAEALDAA-PNLKIISCHGSGTNRIAKAAAAARGVLVTN 91
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
PN S +VAE+ +GLLL+ RR E VR G WE + G +L T+G++G G
Sbjct: 92 APNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTG-KGMELHTRTLGLVGFGA 150
Query: 535 IGQAVVK 555
I + V +
Sbjct: 151 IARHVAQ 157
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 74.5 bits (175), Expect = 2e-12
Identities = 42/133 (31%), Positives = 73/133 (54%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
+E++L+ + G AL+ S + + +L+ A QL+++ G ++ E +GI +
Sbjct: 34 KEQLLEQLKGADALIVRSAVFVDAAMLEHAD-QLRVIGRAGVGVDNIELEAATRKGIAVM 92
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
NTP + AVAE +GL+L+ +R + + G+WE + G +LR T+GI+GLG
Sbjct: 93 NTPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWE--KKSLQGTELRGKTLGIVGLG 150
Query: 532 GIGQAVVKRLSGF 570
IG V +R + F
Sbjct: 151 RIGLEVARRAASF 163
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 74.5 bits (175), Expect = 2e-12
Identities = 44/140 (31%), Positives = 73/140 (52%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R E+L +P A++ S + E L AA +LK+++ G ++ + G+ +
Sbjct: 42 RGELLAALPEADAILVRSATKVDAEAL-AAARRLKVIARAGVGLDNVDVRAATQAGVMVV 100
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
N P + AE+AV L+L+A+R + ++ GEW+ + G +L + TVGI+GLG
Sbjct: 101 NAPTSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRA--RYTGTELYEKTVGIVGLG 158
Query: 532 GIGQAVVKRLSGFDVARFIY 591
IG V +RLS F + Y
Sbjct: 159 RIGVLVAQRLSAFGMKIVAY 178
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/136 (31%), Positives = 70/136 (51%)
Frame = +1
Query: 220 ISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVG 399
I+ + NE + +LK ++ G ++ + + GI +TN P + AVAE+ +G
Sbjct: 55 IAGVDTWNERVFNLAPRLKAIARFGVGVDNIDIDAAHRHGIAVTNAPGGNANAVAELTLG 114
Query: 400 LLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVA 579
L+LSA RR D +R G W D+ +GQ+L VG++G G I + + ++L GFDV
Sbjct: 115 LILSAMRRIPYLHDALRGGAW----DRFVGQELIGRRVGLLGFGNIARKIARKLCGFDVE 170
Query: 580 RFIYSGHREKPEAKAL 627
Y ++ A L
Sbjct: 171 VIAYDKFPDQVAATKL 186
>UniRef50_Q11BV4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 307
Score = 74.1 bits (174), Expect = 2e-12
Identities = 63/189 (33%), Positives = 97/189 (51%), Gaps = 2/189 (1%)
Frame = +1
Query: 58 VLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPI 237
V++ + P + L +HF+VL+ + G E L E I G + L P+
Sbjct: 6 VILQATSLPAPTVNTLREHFSVLELP--SQGAERDRL-IEANRDRIRGIATL---GAGPV 59
Query: 238 TNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSAS 417
++ L+I++ SAG + + E +AR I +TNT VL+ VA++AV +L S
Sbjct: 60 DAALIGRLPA-LEIIACFSAGMDGIDLEAAKARNIAVTNTSPVLADDVADLAVVMLFSLL 118
Query: 418 RRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRL--SGFDVARFIY 591
R + R G W G + L + +R VGIIGLG IG+AV +RL SG ++A Y
Sbjct: 119 RGISRAERYARAGLWPDG-NLPLARTVRGCRVGIIGLGHIGKAVARRLECSGAEIA---Y 174
Query: 592 SGHREKPEA 618
+G R KP++
Sbjct: 175 NGPRRKPDS 183
>UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 309
Score = 74.1 bits (174), Expect = 2e-12
Identities = 42/113 (37%), Positives = 64/113 (56%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
+++V+T GY++ L+A I+ +NTP VL+ AV E+A+G++LS RR E+ + V+
Sbjct: 64 IRLVATCGVGYDNLPLPYLKANNIKASNTPGVLNDAVCELAIGMMLSLMRRIPESQEYVK 123
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREK 609
W K L L VGI G+G IGQ + +RL F V + Y+G K
Sbjct: 124 SSAWSKAPFK-LTTTLAGKRVGIAGMGRIGQDLAQRLEPFKV-KIAYTGPSPK 174
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/130 (31%), Positives = 69/130 (53%)
Frame = +1
Query: 169 GREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQL 348
G EEI ++P A++ S IT E+++ A +LK++ G ++ + + ARG +
Sbjct: 32 GAEEIKAMLPDYDAVIVRSRTRITAELIENA-PRLKVIGRAGTGVDNIDVKAASARGALV 90
Query: 349 TNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGL 528
NTP + A AE + ++L+ +R + +R G W+ + +G +L T+GIIGL
Sbjct: 91 MNTPGANATAAAEHTIAMMLALARHIPQATQSMREGRWD--KKRFMGTELFHQTLGIIGL 148
Query: 529 GGIGQAVVKR 558
G IG V R
Sbjct: 149 GKIGSIVADR 158
>UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep:
AFR675Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 353
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/101 (39%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +1
Query: 295 AGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIG- 471
AGY+ +PE R IQ+ N P +++ A+ V LLL+A R F +R+G W
Sbjct: 90 AGYDQIDPESFTKRQIQVANVPGLVNAPTADTHVFLLLAALRNFCHGQLLLRQGRWPDAP 149
Query: 472 -FDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
G D TVG++G+GGIG+AVV+RL F R IY
Sbjct: 150 VAGTPFGHDPAGKTVGVLGMGGIGRAVVQRLRPFGFERIIY 190
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 74.1 bits (174), Expect = 2e-12
Identities = 45/149 (30%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNH-CNPEELRARGI 342
L +EI++ + G A + +T +I+ +A LK++S GY + + + I
Sbjct: 44 LKEDEIIEALAGVDAYIPGGEEVVTEKIIASAKNTLKVISFNGVGYGYYVDVPAAKKHNI 103
Query: 343 QLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGII 522
+TN P+ S AV+E V L+L+ ++ + + G W K + QD+ D T+GI+
Sbjct: 104 AVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWH----KYISQDVSDKTIGIV 159
Query: 523 GLGGIGQAVVKRL-SGFDVARFIYSGHRE 606
G+G IG+ V K++ GF YS RE
Sbjct: 160 GMGSIGRLVAKKMYYGFGCKILYYSRTRE 188
>UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=13; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Brucella abortus
Length = 324
Score = 73.7 bits (173), Expect = 3e-12
Identities = 39/113 (34%), Positives = 63/113 (55%), Gaps = 1/113 (0%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
++ +++DA L+I+ GY+ + A + +TNTP+VL+ VA+ +GLL+
Sbjct: 56 VSADLIDAL-PNLEIIGNFGVGYDAVDARHAGANNVMVTNTPDVLTEEVADTTIGLLIDT 114
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQ-DLRDSTVGIIGLGGIGQAVVKRLSGF 570
R ++ + +RRGEW L + LR VGI GLG IG+AV +R+ F
Sbjct: 115 VRELSKAQEFLRRGEWGKQVRYPLSKLSLRGRKVGIFGLGRIGKAVARRIEAF 167
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 73.7 bits (173), Expect = 3e-12
Identities = 46/151 (30%), Positives = 75/151 (49%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E++L+L+ A+ S IT E++ AA QLK+V G ++ + E RG+ + N
Sbjct: 34 EKVLELVKDVHAIAVRSETKITREVI-AAAPQLKVVGRAGVGVDNVDVEAATERGVVVMN 92
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP + A AE+ +L SR ++ +R G+W+ G +L T+G+IG+G
Sbjct: 93 TPAGNTIATAELTFTHILCGSRPVSQAAASMREGKWD--RKSFSGVELFKKTLGVIGMGR 150
Query: 535 IGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
IG V +R F + Y + AKA+
Sbjct: 151 IGGEVARRAVAFGMKVLAYDPYLAPSRAKAM 181
>UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 332
Score = 73.7 bits (173), Expect = 3e-12
Identities = 41/121 (33%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Frame = +1
Query: 268 QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQV 447
+L+++S+ G +H + RGI++ NTP V+ A+ A+GLLL+++R+ +
Sbjct: 69 ELRVISSAGVGVDHIDLAAATIRGIRVGNTPGVVQECTADHAIGLLLASARKICSGDSVI 128
Query: 448 RR-GEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
R+ G + G + ST+GI+GLGG+G AV R GF + R +Y +R + E K
Sbjct: 129 RQPGFSKESIFNSFGTKVTGSTLGIVGLGGVGSAVANRAKGFKM-RILYH-NRTRKEDKE 186
Query: 625 L 627
L
Sbjct: 187 L 187
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/144 (31%), Positives = 76/144 (52%), Gaps = 3/144 (2%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAA---GTQLKIVSTVSAGYNHCNPEELRARGI 342
++E+L I LV S +T E++DAA G +LK++ G ++ + R +G+
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARDKGL 91
Query: 343 QLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGII 522
+ NTPN S +VAE+A+G + + SR +R+G+WE G ++ T+G+I
Sbjct: 92 TVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWE--KKAYTGTEIFGKTLGLI 149
Query: 523 GLGGIGQAVVKRLSGFDVARFIYS 594
G G I + V KR + + IY+
Sbjct: 150 GFGRIAREVAKRAEALGM-KVIYN 172
>UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3;
Cyanobacteria|Rep: Glycerate dehydrogenase - Anabaena
sp. (strain PCC 7120)
Length = 332
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/143 (31%), Positives = 75/143 (52%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L REEIL+ AL+ I L +LKI++ GY++ + RGI
Sbjct: 34 LSREEILQRAKDAEALMVFMPDTIDEAFLREC-PKLKIIAAALKGYDNFDVAACTHRGIW 92
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
T P++LS AE+ +GLL+ R+ E +R G++ + L + T+GI+G
Sbjct: 93 FTIVPSLLSAPTAEITIGLLIGLGRQMLEGDRFIRTGKFTGWRPQFYSLGLANRTLGIVG 152
Query: 526 LGGIGQAVVKRLSGFDVARFIYS 594
+G +G+A+ RL+GF++ + +YS
Sbjct: 153 MGALGKAIAGRLAGFEM-QLLYS 174
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 73.3 bits (172), Expect = 4e-12
Identities = 43/145 (29%), Positives = 74/145 (51%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+E+ L+ C A + +S P T E+L A LK+++ V G + + + + G+ ++
Sbjct: 41 DELATLLEDCDAAI-VSTDPFTREVL-AGDRNLKVIARVGVGTDSIDHDAAKEFGVGISV 98
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP + + VA+ + ++L RR V+ G W+ + +L TVG+IG G
Sbjct: 99 TPGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWD-RVGEATPTELYRKTVGLIGAGI 157
Query: 535 IGQAVVKRLSGFDVARFIYSGHREK 609
IG+AV++RL GF V + EK
Sbjct: 158 IGKAVIRRLLGFGVRVLYFDAMVEK 182
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/180 (27%), Positives = 94/180 (52%)
Frame = +1
Query: 52 LKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNL 231
++VL+S N + LK+ D + + Y Q G T + +LK+I AL+
Sbjct: 1 MQVLISDN-FSSAGLKLF-DEAEGITADY----QPGIT--HDNLLKIINNYDALIVRGGT 52
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
++ E++ AA +LKI++ G + + +GI +TNTP + +AE A+ +++S
Sbjct: 53 TVSEELIFAA-KRLKIIARAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMS 111
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+R + + + +G+W+ + LG D+ D T+G+IG G IG+ V++ G + +Y
Sbjct: 112 LARLIPQAHESMSQGKWQ--STEFLGSDINDKTLGVIGGGKIGRRVIEYARGLHMHVNLY 169
>UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 315
Score = 73.3 bits (172), Expect = 4e-12
Identities = 40/115 (34%), Positives = 64/115 (55%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+++S + GY+ + R I++T+TP VL+ VA++A+GL+LS +RR + VR
Sbjct: 67 LEMISIMGVGYDGVDVTAALERNIRVTHTPGVLNDDVADLAIGLMLSVARRIPQADQYVR 126
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
G W G L + + +GI+GLG IGQA+ R F ++ Y+ K E
Sbjct: 127 SGRWPEG-PMPLARKVSGERLGIVGLGRIGQAIATRAEAFGMS-VAYTARSRKAE 179
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/142 (29%), Positives = 74/142 (52%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L +E++++ I +AL+ S +T E++ AAG LKI+ G ++ + +GI
Sbjct: 31 LTKEQLIEKIKDYNALIIRSETQVTKEVI-AAGKNLKIIGRAGVGIDNVDVPAATEKGII 89
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P + A E + ++L+ SR + ++ G+WE K +G ++ + T+GIIG
Sbjct: 90 VANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSGKWE--RSKFMGVEVMNKTLGIIG 147
Query: 526 LGGIGQAVVKRLSGFDVARFIY 591
LG IG + KR F + Y
Sbjct: 148 LGRIGGEITKRARSFGMEVLAY 169
>UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome
shotgun sequence; n=8; Chordata|Rep: Chromosome 21
SCAF14577, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 324
Score = 72.9 bits (171), Expect = 6e-12
Identities = 38/117 (32%), Positives = 67/117 (57%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
LK+V++ AG +H + + + G+++T+TP V+S A A++A+GLLL AS R ++
Sbjct: 71 LKVVASGGAGIDHLDVAYINSLGVKVTHTPGVVSSATADIALGLLL-ASARDIVTYHRIA 129
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
++G D+ ST+GI+G+G IG + +R GF++ ++ R K K
Sbjct: 130 ADPKTADLPTMMGVDVTGSTMGIVGMGDIGYKIAQRGRGFEMKILYHNRRRRKVSVK 186
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 72.9 bits (171), Expect = 6e-12
Identities = 50/164 (30%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +1
Query: 106 EDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSA-LVWISNLPITNEILDAAGTQLKIV 282
E + LQ+R L ++G + + L G A L+ +PI++++ DA +L+IV
Sbjct: 41 ETDWQKLQNRRLEVEKKGPEIEEVDALIQSEGKDAELLAGLFVPISSKVFDAM-PKLRIV 99
Query: 283 STVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEW 462
AG + N +E RGI + N + AV++ VGL+L+ R ++ G W
Sbjct: 100 GVSRAGLENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGW 159
Query: 463 EIGF-DKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
F + +L+ VG++G G IG+ V ++LSGF V R +Y
Sbjct: 160 RKEFSNSDWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVY 203
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 72.9 bits (171), Expect = 6e-12
Identities = 45/133 (33%), Positives = 71/133 (53%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R ++L +P AL+ S + E+L AA +LKIV+ G ++ + + ARG+ +
Sbjct: 34 RTKLLAAVPEADALLVRSATTVDAEVL-AAAPKLKIVARAGVGLDNVDVDAATARGVLVV 92
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
N P + AE A+ LLL+ASR+ E +R W+ G ++ TVG++GLG
Sbjct: 93 NAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWK--RSSFSGTEIFGKTVGVVGLG 150
Query: 532 GIGQAVVKRLSGF 570
IGQ V R++ F
Sbjct: 151 RIGQLVAARIAAF 163
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 72.5 bits (170), Expect = 7e-12
Identities = 45/131 (34%), Positives = 71/131 (54%)
Frame = +1
Query: 157 GSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRAR 336
G L E + L+ C A+ P+T ++DA LK++S G ++ + E RAR
Sbjct: 34 GRKLTENETIDLLQDCVAVA-AGTEPLTARVMDAL-PGLKVISRCGTGMDNVDMEAARAR 91
Query: 337 GIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVG 516
GI + NTP+ + AVAE+ +GL L R+ + ++R G W+ K +G L +G
Sbjct: 92 GIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRSGVWK----KRMGNLLGGKRLG 147
Query: 517 IIGLGGIGQAV 549
I+G+G IG+AV
Sbjct: 148 IVGMGRIGRAV 158
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 72.5 bits (170), Expect = 7e-12
Identities = 46/149 (30%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE+L++I A++ S P+T E+L+ A +LK+V G ++ + EE RGI + N
Sbjct: 35 EELLEIIKDFDAIITRSRTPVTKELLERA-EKLKVVGRAGVGVDNVDIEEATKRGILVVN 93
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP + E+ + +L+ R + + + +W+ K +G++L +GIIGLG
Sbjct: 94 TPGANTIGATELTMMHMLTIMRNGHKAHESMLNYKWDR--KKFMGEELYGRILGIIGLGN 151
Query: 535 IGQAVVKRLSGFDVARFIYSGH--REKPE 615
IG V R F + Y + REK E
Sbjct: 152 IGSQVAIRAKAFGMKVMAYDPYIPREKAE 180
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 72.5 bits (170), Expect = 7e-12
Identities = 50/183 (27%), Positives = 87/183 (47%)
Frame = +1
Query: 52 LKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNL 231
+KVL+S N P KI+ D + R + L EE++K+IP LV S
Sbjct: 1 MKVLISDN-LAPVGEKIMRDAGLEVDVR--------TGLSPEELVKIIPAYDGLVIRSAS 51
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
+T EIL+AA LK+V G ++ + +G+ + N P+ + AE AV ++++
Sbjct: 52 KVTAEILEAA-ENLKVVGRAGIGLDNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMA 110
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+R + ++ G+WE K G ++ G++G+G IG+ +R G + +
Sbjct: 111 LTRNIPQATASMKAGKWE--KKKFQGHEVTAKVAGVVGIGRIGRIFAERAMGLRMKVIAF 168
Query: 592 SGH 600
H
Sbjct: 169 DPH 171
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 72.5 bits (170), Expect = 7e-12
Identities = 42/124 (33%), Positives = 70/124 (56%), Gaps = 1/124 (0%)
Frame = +1
Query: 208 ALVWISNL-PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVA 384
A VW+ + + E L+AA LK++ G + + + ARGI + N P + +VA
Sbjct: 52 AHVWVVGINKVYAEDLEAA-PNLKLIIKHGTGVDSIDLKAAAARGITVANAPGTNANSVA 110
Query: 385 EVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS 564
++A G +LS +R+ + R G W V+G+D+ T+G++GLG IG+ V++R S
Sbjct: 111 DLAFGFMLSLARQIVSADKRTRDGFW----GTVMGKDVYGKTLGVLGLGQIGKGVIRRAS 166
Query: 565 GFDV 576
GFD+
Sbjct: 167 GFDM 170
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/129 (37%), Positives = 65/129 (50%)
Frame = +1
Query: 211 LVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEV 390
L+ SN + +L+ L+++ST GY+ +ARGI +T+TP VL AV E+
Sbjct: 43 LITRSNYQVPLALLELLPA-LQVISTCGVGYDGIPVAYAQARGIAVTHTPGVLDDAVCEL 101
Query: 391 AVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
VGLLL R + VR G W L L VGI+GLG IG+ + RL F
Sbjct: 102 GVGLLLGLLRDIPASDRFVRDGRWS-DSAYPLTTSLAGKAVGIVGLGRIGRGIAARLQPF 160
Query: 571 DVARFIYSG 597
VA YSG
Sbjct: 161 GVA-LAYSG 168
>UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Acidiphilium cryptum
(strain JF-5)
Length = 332
Score = 72.5 bits (170), Expect = 7e-12
Identities = 42/122 (34%), Positives = 65/122 (53%)
Frame = +1
Query: 238 TNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSAS 417
T+ L A L++++ GY+ + G+ +TNTP+VLS + + VGLLL+
Sbjct: 57 TDAALIARLPALELIANFGVGYDTVDAVAAAKHGVIVTNTPDVLSDEMGDFTVGLLLATI 116
Query: 418 RRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSG 597
R +R G+W + LG LR +GI G+G IGQ + +RLSGFD+ +S
Sbjct: 117 RTLPAAERFLRAGKW-LHDAFPLGNSLRGRRIGIAGMGRIGQVIARRLSGFDLPISYHSR 175
Query: 598 HR 603
+R
Sbjct: 176 NR 177
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 72.1 bits (169), Expect = 1e-11
Identities = 44/128 (34%), Positives = 74/128 (57%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E I I CS L+ + +P T E+ DAA LK++ GY++ + E A+GI++
Sbjct: 35 ENICNNIGDCSGLL-LRTVPCTKEVFDAA-PHLKVIGRHGVGYDNIDIAEATAQGIKVCY 92
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP + +VAE + LLL+ ++ ++R+G +EI +++ G D+ T+GIIG G
Sbjct: 93 TPLANANSVAEHTIMLLLACAKNIVIADKELRQGNYEIR-NQMPGIDVFGKTLGIIGFGR 151
Query: 535 IGQAVVKR 558
IG++V K+
Sbjct: 152 IGKSVAKK 159
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 72.1 bits (169), Expect = 1e-11
Identities = 43/150 (28%), Positives = 76/150 (50%)
Frame = +1
Query: 178 EILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNT 357
E+L+ I L+ S +T E+++AAG +LK + G ++ + E RGI + N
Sbjct: 33 ELLERIGEYDGLIVRSATKVTAEVIEAAG-RLKAIGRAGIGVDNIDIEAATKRGILVANA 91
Query: 358 PNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGI 537
P + A AE +GL+L+ +RR +RRGEW K G ++ + T+G++GLG +
Sbjct: 92 PESNTVAAAEHTLGLMLAVARRIPAADASLRRGEWNRAAFK--GVEVAEKTLGLVGLGHV 149
Query: 538 GQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G V + G + Y + + +++
Sbjct: 150 GSIVARGALGMGMRVLAYDPYVSEERMRSM 179
>UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10;
Bacteria|Rep: D-lactate dehydrogenase - Fusobacterium
nucleatum subsp. vincentii ATCC 49256
Length = 339
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/140 (32%), Positives = 74/140 (52%), Gaps = 1/140 (0%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDA-AGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
EE L G + +N I E +D A +K+++ AG+N+ + +++ R ++
Sbjct: 44 EETANLTKGYDVVCGFANDNINKETIDIMAKNGIKLLAMRCAGFNNVSLKDIHNR-FKVV 102
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
P A+AE VGL+L+ +R+ + + R G + I + ++G DL TVGIIG G
Sbjct: 103 RVPAYSPHAIAEYTVGLILAVNRKIHKAYVRTREGNFSI--NGLMGFDLDGKTVGIIGTG 160
Query: 532 GIGQAVVKRLSGFDVARFIY 591
IGQ ++K L GFD+ Y
Sbjct: 161 KIGQILIKILKGFDMKVIAY 180
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 71.7 bits (168), Expect = 1e-11
Identities = 48/173 (27%), Positives = 84/173 (48%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
+V+V+ + A+ L+D + L G+ L E+I L+ G V + +
Sbjct: 7 RVVVTQKFFDDAAIAFLQDRNIEVILPNLPEGKGEGDLNVEDIRLLLEGAGGWV-VGHAR 65
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
IT + +A L ++S GY + E R G + +VA+ +G+++S
Sbjct: 66 ITRAVFEAL-PDLAVISRRGVGYEKVDVEAARDLGRVVAIAAGGNDASVADQVIGMMISI 124
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFD 573
RRF E ++ G+W I ++G +L VGI+G G IG+++ +RLSGF+
Sbjct: 125 GRRFQEAQSAMKAGKWNI----LVGTELYRRKVGIVGFGRIGRSLARRLSGFE 173
>UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Rhodobacterales|Rep: Putative
D-isomer specific 2-hydroxyacid dehydrogenase -
Rhodobacterales bacterium HTCC2150
Length = 313
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/118 (33%), Positives = 63/118 (53%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
AA +K++S GY+ + RGI +T+TPNVL+ VA + L+L+ R +
Sbjct: 60 AALPDVKLISCYGVGYDAIDTTTAVERGITVTHTPNVLNDEVATTTIMLMLACYRNLIND 119
Query: 436 LDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREK 609
VR G+WE + L + + VGI+GLG IGQA+ +L+ F+ + Y +K
Sbjct: 120 DAYVRAGKWEAEGNTPLTRSADNRRVGILGLGRIGQAIADKLAAFN-SEISYHSRNQK 176
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 71.7 bits (168), Expect = 1e-11
Identities = 41/119 (34%), Positives = 68/119 (57%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+T E+L A +L++++T S GY+H + + RA GI ++N P+ VAE A LLL+
Sbjct: 54 LTAEVL-AQFPRLRLIATRSTGYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAV 112
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
SR ++ RRG++ + G +LR T+G++G G IG+ V++ GF + Y
Sbjct: 113 SRHIVTGAERTRRGDF--SQHGLRGFELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVAY 169
>UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pseudomonas putida
W619|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas putida W619
Length = 312
Score = 71.7 bits (168), Expect = 1e-11
Identities = 44/112 (39%), Positives = 62/112 (55%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L +++ G + + ++++ARGI++ T ++L+ AVA+ AV LLLS R+ VR
Sbjct: 75 LSLIAVNGVGVDGIDLDQVKARGIRVETTIDILTDAVADHAVALLLSLLRQVCVADRFVR 134
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
G W G LG LR VGIIGLG IGQA+ RL F V + Y E
Sbjct: 135 AGMWREGAFPSLGTTLRGLRVGIIGLGRIGQAIASRLLPFGV-KLAYHNRNE 185
>UniRef50_A0R5A8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=9; Bacteria|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 337
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/119 (37%), Positives = 60/119 (50%)
Frame = +1
Query: 250 LDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFT 429
L +A L V GY+ + + AR I ++NTP+VLS VA+ AVGLL+ R+F+
Sbjct: 72 LMSALPNLGAVVNFGVGYDTTDVDAAAARDIVVSNTPDVLSDCVADTAVGLLIDVMRKFS 131
Query: 430 ENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
+ VR W + L + S VGIIGLG IG A+ RL F Y RE
Sbjct: 132 ASDRYVRARRWVTEGNYPLAHKVSGSRVGIIGLGRIGTAIATRLGAFG-CTISYHNRRE 189
>UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidobacteria bacterium
Ellin345|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Acidobacteria bacterium
(strain Ellin345)
Length = 371
Score = 71.3 bits (167), Expect = 2e-11
Identities = 42/148 (28%), Positives = 75/148 (50%), Gaps = 3/148 (2%)
Frame = +1
Query: 181 ILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTP 360
I K+ G L+ I E+ +A LK+V+ ++ G+++ N + + T+T
Sbjct: 44 IEKVASGIDGLITTLRDKIDAEVFEAGKGNLKVVAQIAVGFDNINRADANKYKVPFTHTA 103
Query: 361 NVLSPAVAEVAVGLLLSASRRF---TENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
+VL+ A AE A ++ +A+R+ N+ ++ G W F LG ++ ++ IIG G
Sbjct: 104 DVLTEATAEFAFFIMAAAARKLWTAERNVRDLKWGTWH-PFLPFLGDEVTGKSIAIIGTG 162
Query: 532 GIGQAVVKRLSGFDVARFIYSGHREKPE 615
IG A++K+ SGFD+ Y + E
Sbjct: 163 RIGLAMIKKCSGFDMNILCYDAAYQNRE 190
>UniRef50_P53839 Cluster: Putative 2-hydroxyacid dehydrogenase
YNL274C; n=13; Saccharomycetales|Rep: Putative
2-hydroxyacid dehydrogenase YNL274C - Saccharomyces
cerevisiae (Baker's yeast)
Length = 350
Score = 71.3 bits (167), Expect = 2e-11
Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 3/126 (2%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E+ A + + V AGY+ + E + R IQ+ N P+++S A A+ V LLL A R
Sbjct: 74 ELALALPSSVVAVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRN 133
Query: 424 FTENLDQVRRGEW-EIG--FDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYS 594
F ++ G W E G G D TVGI+GLG IG+ +++RL F FIY
Sbjct: 134 FGIGNRRLIEGNWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFENFIYH 193
Query: 595 GHREKP 612
+ P
Sbjct: 194 NRHQLP 199
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 70.9 bits (166), Expect = 2e-11
Identities = 48/172 (27%), Positives = 83/172 (48%), Gaps = 2/172 (1%)
Frame = +1
Query: 118 TVLQSRYLN--FGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTV 291
T+L+ R L + G T EE L L G + S P+ ++L A LK+++
Sbjct: 20 TMLRDRGLEPVYSPAGGTRTDEEKLALFEGAVGAIAASE-PVARDML-ATSPMLKVIARA 77
Query: 292 SAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIG 471
GY++ + + GI++ NTP V AVAE+A+ L+L+ +RR L V G W
Sbjct: 78 GVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDDGGW--- 134
Query: 472 FDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
+ G +LR ++G+IG G G+A+ + + + H + ++ +
Sbjct: 135 -PREAGTELRGKSLGVIGYGPSGKAIAALGVALGMRVLVSTAHPDSEQSSGI 185
>UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic component; n=1; Nitratiruptor
sp. SB155-2|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic component - Nitratiruptor sp.
(strain SB155-2)
Length = 314
Score = 70.9 bits (166), Expect = 2e-11
Identities = 38/117 (32%), Positives = 66/117 (56%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+ + T S G++H + EE + RGI ++N P VAE A LLL+ SR+ + + +
Sbjct: 62 LRYIQTRSTGFDHIDLEECKKRGIIVSNVQGYAGPPVAEFAFSLLLNISRKTDIAIARAK 121
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
G + + +LG +L + ++GI+GLG IG+ + + SGF + Y+ H ++ K
Sbjct: 122 EGSFV--YKDLLGFELFEKSIGIVGLGTIGKQMARIASGFGMKTKAYTHHFDETFCK 176
>UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema
pallidum|Rep: D-lactate dehydrogenase - Treponema
pallidum
Length = 331
Score = 70.9 bits (166), Expect = 2e-11
Identities = 48/140 (34%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = +1
Query: 151 QEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGT-QLKIVSTVSAGYNHCNPEEL 327
+E T +E+LK G LV + L + +E+ D G +LK++ST +AG++ N L
Sbjct: 32 EEPLTAKNKELLK---GYEGLVVMQFLAMEDEVYDYMGACKLKVLSTRTAGFDMYNATLL 88
Query: 328 RARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDS 507
+ GI+LTN P+ A+ E A+ L +R E VR+ ++ +L ++LR S
Sbjct: 89 KKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIETFVRKRDFR-WQKPILSKELRCS 147
Query: 508 TVGIIGLGGIGQAVVKRLSG 567
VGI+G G IGQA + G
Sbjct: 148 RVGILGTGRIGQAAARLFKG 167
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 70.5 bits (165), Expect = 3e-11
Identities = 47/144 (32%), Positives = 72/144 (50%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R++ LK+ +V S + I E L +A TQL+ ++ V AG + + + +
Sbjct: 35 RDDYLKIASQYLGVVIRSKIKIDAEFLSSA-TQLRFIARVGAGMENIDIQSADKHQVVCL 93
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
N P AVAE AVG++L+ R +VR+G W ++ G +L TVGIIG G
Sbjct: 94 NAPEGNRDAVAEQAVGMILTLFNRLLIADAEVRKGIWL--REQNRGIELGGKTVGIIGYG 151
Query: 532 GIGQAVVKRLSGFDVARFIYSGHR 603
G A ++L GFDV Y ++
Sbjct: 152 NTGSAFARKLQGFDVRILAYDKYK 175
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 70.5 bits (165), Expect = 3e-11
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +1
Query: 139 LNFGQEGSTLGREEILKLIPGCSALVWISNL-PITNEILDAAGTQLKIVSTVSAGYNHCN 315
L F G E++ L+PGC + W++ + P++++++ AA L+ +S G ++
Sbjct: 29 LVFPTPGRMPSEAELIGLVPGC--IGWLAGVEPVSDKVI-AAADSLRAISRNGTGIDNLP 85
Query: 316 PEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQD 495
L+ RGI + + VAE++VGL+L+A R +R G W + G++
Sbjct: 86 LPLLKERGIGILKAEGANAVGVAELSVGLMLAALRHIPAETAGIRAGGW----PRSRGRE 141
Query: 496 LRDSTVGIIGLGGIGQAVVKRLS 564
+ + TVGIIG G IG+ V + +S
Sbjct: 142 IAERTVGIIGCGAIGKRVARAVS 164
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/108 (36%), Positives = 64/108 (59%)
Frame = +1
Query: 268 QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQV 447
+L++V+T SAG++H + E R RGI + + P+ S +VAE A LLL +R T+ ++
Sbjct: 71 RLRLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERA 130
Query: 448 RRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
R+G + + + G +L T+GI+GLG IG+ V + GF + Y
Sbjct: 131 RQGSF--AYRGLTGFELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAY 176
>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
aurescens (strain TC1)
Length = 329
Score = 70.5 bits (165), Expect = 3e-11
Identities = 41/107 (38%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = +1
Query: 259 AGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENL 438
A ++K VS + GYN+ + + GI + NTP VL+ A A+VA+ L+L +RR E+
Sbjct: 63 ANARVKGVSNYAVGYNNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESD 122
Query: 439 DQVRRGE---WEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
VR G+ WE F +LG+D+ + +G+ G G I +AV +R GF
Sbjct: 123 RVVRDGKFLGWEPEF--MLGRDVSGAVLGLAGFGRIARAVARRALGF 167
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 70.1 bits (164), Expect = 4e-11
Identities = 49/156 (31%), Positives = 77/156 (49%)
Frame = +1
Query: 100 ILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKI 279
I ED + Q + + + L +E+ + I LV S +T EIL A +LK+
Sbjct: 13 ISEDGVRIFQKAGFHVDMK-TKLSPQELAQEISQYDGLVIRSGTKVTREILKNAD-RLKV 70
Query: 280 VSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGE 459
+ AG ++ + E RGI + NTP + AE + LL+S +RR + + G+
Sbjct: 71 IGRAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAGK 130
Query: 460 WEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSG 567
WE K +G +L T+GI+G+G IGQ V + G
Sbjct: 131 WE--KSKFMGVELFQKTLGIVGMGKIGQHVAQIARG 164
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 70.1 bits (164), Expect = 4e-11
Identities = 50/156 (32%), Positives = 80/156 (51%), Gaps = 5/156 (3%)
Frame = +1
Query: 118 TVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSA 297
++L+SR + G + R EIL ++ L+ S I +++ A ++LK+++ A
Sbjct: 17 SLLESRGIQ-GDYRPDITRAEILTIVDKYEGLMVRSKTAIDEDLIGRA-SRLKVIARAGA 74
Query: 298 GYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEI-GF 474
G + + ARGI++ N P AV E +G+LLS L V+R +WE+ F
Sbjct: 75 GLDKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSL-------LHNVQRADWEVKNF 127
Query: 475 ----DKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
+ G +L D VG+IG G +G+A KRLS F
Sbjct: 128 AWKREANRGVELMDKVVGVIGYGNMGKAFAKRLSSF 163
>UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1;
Aegilops tauschii|Rep: Putative uncharacterized protein
- Aegilops tauschii (Tausch's goatgrass) (Aegilops
squarrosa)
Length = 573
Score = 70.1 bits (164), Expect = 4e-11
Identities = 50/121 (41%), Positives = 63/121 (52%), Gaps = 1/121 (0%)
Frame = +1
Query: 250 LDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFT 429
LDA + L+ V SAG +H + E RG+ + N V S VA+ AVGLL+ RR +
Sbjct: 320 LDAVPS-LRCVLFNSAGLDHVDLLECERRGVAVANATGVYSADVADYAVGLLIDVLRRVS 378
Query: 430 ENLDQVRRGEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
+ VRRG W E G G L VGIIGLG IG A+ RL F+ A Y R+
Sbjct: 379 ASDRHVRRGHWPERGGH---GFTLGRKRVGIIGLGSIGSAIATRLEAFNCA-VSYHSRRQ 434
Query: 607 K 609
K
Sbjct: 435 K 435
>UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=2; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 322
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/170 (28%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = +1
Query: 70 SNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEI 249
+ D P +++L+ HFT + + + + REE ++ + I EI
Sbjct: 15 TRDVKPGGMELLKKHFTDII-----LPSKPNGIPREEFIEKAKKADIIYADRRDVINKEI 69
Query: 250 LDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFT 429
LD +LK+++ +AGY++ + R I + NT L+ A+ L+++ +RR
Sbjct: 70 LD--NPKLKLITVCAAGYDNIDINYATKRKIIVANTHKSLADTCADTIWSLIMACARRVV 127
Query: 430 ENLDQVRRGEWEIGFDKVL-GQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
E V+ G+WE + L G ++ T+G+IG G IG+AV KR GF++
Sbjct: 128 EADQFVKNGDWEKTSPQCLWGINVHHKTLGVIGAGHIGRAVAKRGEGFNM 177
>UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 413
Score = 70.1 bits (164), Expect = 4e-11
Identities = 38/121 (31%), Positives = 63/121 (52%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E++ + L+ + AGY+ + + L +GIQ +N P + A ++VA+ LLL A RR
Sbjct: 139 ELVSQLPSTLRYIVHNGAGYDQLDVQALSDKGIQASNVPTAVDDATSDVALYLLLGALRR 198
Query: 424 FTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHR 603
F Q+ G++ F + +D R T+GI+G GGIG+A + S + IY
Sbjct: 199 FPRAKAQMNAGKFNSAFSFLDARDPRGKTLGIVGAGGIGRAFAHKASHALGVKVIYHNRN 258
Query: 604 E 606
+
Sbjct: 259 Q 259
>UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3;
Mesorhizobium loti|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 341
Score = 69.7 bits (163), Expect = 5e-11
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+E++ GC AL+ S IT ++ A L+ +S G + + + GI +++
Sbjct: 49 DELIAKAHGCIALMGASGTRITRRVMQAL-PDLRYISKYGIGVDSIDIDAATEHGILVSS 107
Query: 355 TPNVLSP-AVAEVAVGLLLSASRRF-TENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGL 528
TPN V+E AV L+L+ +++ T + +RRG W G G LR +TVGI+GL
Sbjct: 108 TPNDFQIFTVSEHAVALMLAVAKQLGTWTPEFMRRGGWR-GLTH--GATLRGATVGIVGL 164
Query: 529 GGIGQAVVKRLSGFDVARFIY 591
G IG+ V +RLSG++ Y
Sbjct: 165 GRIGRGVAQRLSGWEARILAY 185
>UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Zymomonas mobilis|Rep: 2-hydroxyacid dehydrogenase -
Zymomonas mobilis
Length = 309
Score = 69.7 bits (163), Expect = 5e-11
Identities = 37/98 (37%), Positives = 57/98 (58%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+I++ + G++ + E + R I++TNTP VL+ VA++AVGL L+ R N VR
Sbjct: 64 LQIIAQYAVGFDGIDLEAAKKRDIRITNTPGVLTEDVADMAVGLFLTLKRDIIRNDKLVR 123
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS 564
G W + L + VG+ GLG IGQA+ +RL+
Sbjct: 124 DGGWIKKEEIPLSHSASNLDVGVFGLGRIGQAIAERLA 161
>UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospirillum
gryphiswaldense|Rep: Glycolate reductase -
Magnetospirillum gryphiswaldense
Length = 330
Score = 69.7 bits (163), Expect = 5e-11
Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Frame = +1
Query: 250 LDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFT 429
+DA ++I+ T S G NH + + R GI L P ++ A A+ A+ LLL+A RR
Sbjct: 74 IDALPASVRIICTYSVGTNHLDLQAARRHGIALAYAPEAVTEATADTAMLLLLAACRRAH 133
Query: 430 ENLDQVRRGEWEI-GFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
E Q+R+G W + LG D +G++G+G IG+AV +R F
Sbjct: 134 EFQAQLRQGRWGAWNAWENLGWDPGGQILGLVGMGRIGRAVARRARAF 181
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 69.7 bits (163), Expect = 5e-11
Identities = 43/140 (30%), Positives = 74/140 (52%), Gaps = 1/140 (0%)
Frame = +1
Query: 175 EEILK-LIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
+++LK I L+ S +T EIL+ A +LKIV+ G ++ + + + +GI +
Sbjct: 33 KDVLKDKIKEIDVLIVRSATKVTKEILEHAD-KLKIVARAGMGLDNIDVDTAKLKGITVL 91
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
NTP S +VAE+ +G++L R T ++ +WE ++ G +L T GIIG G
Sbjct: 92 NTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWE--KKQLEGFELSQKTFGIIGFG 149
Query: 532 GIGQAVVKRLSGFDVARFIY 591
+G+ + + L GF +Y
Sbjct: 150 YVGKNLAQLLKGFQTNTLVY 169
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 69.7 bits (163), Expect = 5e-11
Identities = 40/154 (25%), Positives = 71/154 (46%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L E++ K + AL+ S +T E+ +AA +LK+V G ++ + + G
Sbjct: 111 LSPEDLKKKVAESDALIVRSGTKVTREVFEAAKGRLKVVGRAGVGIDNVDLQAATEHGCL 170
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P + A AE + LL S +R + ++ G+WE K +G L T+ ++G
Sbjct: 171 VVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWE--RSKYVGVSLVGKTLAVMG 228
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G +G V +R G + + + A+AL
Sbjct: 229 FGKVGTEVARRAKGLGMTVISHDPYAPADRARAL 262
>UniRef50_P30799 Cluster: 2-hydroxyacid dehydrogenase homolog; n=34;
cellular organisms|Rep: 2-hydroxyacid dehydrogenase
homolog - Zymomonas mobilis
Length = 331
Score = 69.7 bits (163), Expect = 5e-11
Identities = 42/128 (32%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +1
Query: 244 EILDA-AGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASR 420
E+L+ AG +K+V+ AGYN+ + + + I++ P +VAE AVG+LL+ +R
Sbjct: 59 EVLEILAGLGIKLVALRCAGYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLNR 118
Query: 421 RFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDVARFIYSG 597
+ + L +VR + + + ++G D+ D TVGIIG+G IG ++ GF Y
Sbjct: 119 QISRGLKRVRENNFSL--EGLIGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAYKP 176
Query: 598 HREKPEAK 621
H + AK
Sbjct: 177 HPDPELAK 184
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 69.3 bits (162), Expect = 7e-11
Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Frame = +1
Query: 214 VWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVA 393
++ +PIT I+DA + K+++ S G + + + ARGI +TN P+ VA+ A
Sbjct: 95 IYAKGIPITKSIIDALES-CKVITLGSVGVDSVDVKAATARGIPVTNIPDTFIEEVADHA 153
Query: 394 VGLLLSASRRFTENLDQVRRGEWEIGFDKVLG-QDLRDSTVGIIGLGGIGQAVVKRLSGF 570
+ LLL+ RR E VR G W G +L L T+G I G + +AV KR + F
Sbjct: 154 MMLLLAGFRRLVEQDRMVRSGRWAEGRPALLKIPRLMGQTLGFISFGRVARAVAKRAAPF 213
Query: 571 DVARFIY 591
+ Y
Sbjct: 214 GLRMMAY 220
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 69.3 bits (162), Expect = 7e-11
Identities = 46/150 (30%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
Frame = +1
Query: 169 GREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQL 348
G++ L + AL+ LP+ E+LDA G +LKIVS GY+H + + ++GI +
Sbjct: 39 GKDWYLANLGDFDALI-TGKLPVDQELLDA-GKKLKIVSATGVGYDHIDVDYASSQGIIV 96
Query: 349 TNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEW-EIGFDKVLGQDLRDSTVGIIG 525
+N P + AE+A LLL+ SR+ ++R+ + + G + GQ T+GI G
Sbjct: 97 SNCPASVMQPTAEMAFTLLLALSRKLALYNQEMRQENFLDTGLLENQGQSPVGKTLGIFG 156
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
+G IG+ + F + +Y + PE
Sbjct: 157 MGRIGKTLASYARTFGM-NILYHNRHQLPE 185
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 69.3 bits (162), Expect = 7e-11
Identities = 42/139 (30%), Positives = 75/139 (53%)
Frame = +1
Query: 154 EGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRA 333
E + +++L +P AL+ +L +T E+++A G +L++++ G ++ + + RA
Sbjct: 34 ETRAMPADDLLARVPEADALIVGMDL-VTAEVIEA-GPRLRVIAKHGVGVDNIDLDAARA 91
Query: 334 RGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTV 513
RGI + P S AVAE+ GL+++A+RR V G+W K+ G +L T+
Sbjct: 92 RGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDW----PKLYGPELAGRTL 147
Query: 514 GIIGLGGIGQAVVKRLSGF 570
G+IG G IG+ + F
Sbjct: 148 GVIGFGRIGRLLAGYAQAF 166
>UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=3; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 396
Score = 69.3 bits (162), Expect = 7e-11
Identities = 42/138 (30%), Positives = 67/138 (48%)
Frame = +1
Query: 214 VWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVA 393
V I + N A L ++ AG N + A+G+ + NTP + + AVAE+A
Sbjct: 45 VLIVRSKVVNAAAIEAAKGLNLIIRAGAGVNTIDVNAASAKGVLVCNTPGMNNDAVAELA 104
Query: 394 VGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFD 573
G ++ R T N +R GEW + + LRD T+GI+G G I +++++ GF
Sbjct: 105 FGHIVCCDRCITTNTAHLRNGEWRKKL-FLTCEGLRDRTLGIVGRGNIAKSMIRIAKGFM 163
Query: 574 VARFIYSGHREKPEAKAL 627
+ ++S EAK L
Sbjct: 164 MNVVVWSRRFTPEEAKEL 181
>UniRef50_Q9A6E7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenases family protein; n=3;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenases family protein - Caulobacter crescentus
(Caulobacter vibrioides)
Length = 319
Score = 68.9 bits (161), Expect = 9e-11
Identities = 43/129 (33%), Positives = 70/129 (54%), Gaps = 2/129 (1%)
Frame = +1
Query: 196 PGCS--ALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVL 369
PG S A+V + ++ ++L A +L +++ VS GY+ + +A GI +T++ +
Sbjct: 47 PGQSIRAIVHAGEMALSRDML-AEMPRLGLIACVSVGYDGVDVPWCKAHGIAVTHSTGLN 105
Query: 370 SPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAV 549
+ VA+ AVGL+L+A R E ++R G W LR G++GLG IG+AV
Sbjct: 106 AADVADHAVGLVLAAWRGIVEGDQRLRGGHWSHAERMAPRPGLRGRKAGVVGLGHIGEAV 165
Query: 550 VKRLSGFDV 576
RL FD+
Sbjct: 166 AARLKAFDM 174
>UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=7;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Silicibacter pomeroyi
Length = 313
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/124 (32%), Positives = 63/124 (50%)
Frame = +1
Query: 199 GCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPA 378
G SA+ ++ + +D L +++ GY+ + ARGI +TNTP VL+
Sbjct: 43 GISAVAYMGHTAFGGAEMDLL-PGLGVIANFGVGYDAIDVAAATARGITVTNTPGVLNDD 101
Query: 379 VAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
VA++AV +LL RR + VR G WE + L + G++GLG IG+ + R
Sbjct: 102 VADLAVTMLLMQCRRMEQGGAWVREGHWETA-NFPLNRKASGGVAGVVGLGRIGREIADR 160
Query: 559 LSGF 570
L+ F
Sbjct: 161 LAAF 164
>UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family; n=2; Cyanobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase family -
Synechocystis sp. (strain PCC 6803)
Length = 318
Score = 68.5 bits (160), Expect = 1e-10
Identities = 45/125 (36%), Positives = 63/125 (50%), Gaps = 2/125 (1%)
Frame = +1
Query: 232 PITNEILDAAGT-QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLL 408
P T +L +LK ++ G + + + GI +NTPNV VA+VA+G L+
Sbjct: 60 PFTARVLTIGKQGKLKALAKWGIGVDAIDLAAAKQLGILTSNTPNVFGDEVADVAIGYLI 119
Query: 409 SASRRFTENLDQ-VRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARF 585
+R +DQ VR+GEW K+ G LR T GIIG+G IGQA+ RL +
Sbjct: 120 LLAREL-HCIDQAVRQGEWL----KIRGHSLRGKTAGIIGVGSIGQAIAVRLQSMGLKLL 174
Query: 586 IYSGH 600
Y H
Sbjct: 175 GYDPH 179
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/140 (30%), Positives = 70/140 (50%)
Frame = +1
Query: 157 GSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRAR 336
G EEI++ AL+ + N + +++ +LKI++ G + + +
Sbjct: 37 GRPFTNEEIIRYASDADALI-VGNDKVPGDVIKKC-KRLKIIAKHGVGVDSIDVKTANQL 94
Query: 337 GIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVG 516
GI +TN P S VA++A GLL +R + + G+W K +G L T+G
Sbjct: 95 GIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWI----KPVGISLSKKTIG 150
Query: 517 IIGLGGIGQAVVKRLSGFDV 576
IIG+G IG AV KR +G+D+
Sbjct: 151 IIGVGTIGTAVAKRATGYDM 170
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 68.5 bits (160), Expect = 1e-10
Identities = 41/140 (29%), Positives = 73/140 (52%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E+ L + +A++ ++++ DA LK+++ GY++ E G+ +TN
Sbjct: 35 EKKLLSLASDAAVIIMTDMAFDKNWFDAL-PNLKLIARRGVGYDNIPVESATKHGVWVTN 93
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP + AVAE+AV L+L+ R+ + + V++GE ++G +L +G+IG G
Sbjct: 94 TPGANAIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASLMGHNLSGKIIGLIGYGQ 153
Query: 535 IGQAVVKRLSGFDVARFIYS 594
I Q + K L GF +YS
Sbjct: 154 IAQNLEKILHGFGAHVLVYS 173
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 68.1 bits (159), Expect = 2e-10
Identities = 40/131 (30%), Positives = 76/131 (58%)
Frame = +1
Query: 157 GSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRAR 336
G +EE+++ I +A++ N P++ E++D A LK++S G ++ + + ++
Sbjct: 35 GGRYSKEELIEKIKDANAII-TGNDPLSREVIDQA-KNLKVISKYGVGLDNIDVDYANSK 92
Query: 337 GIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVG 516
I + N S +VAE+ + ++LS+SR++ E Q R G+ +I +++G +L +G
Sbjct: 93 DIVVHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGK-DI---RLVGYELYQKNLG 148
Query: 517 IIGLGGIGQAV 549
+IGLG IGQ V
Sbjct: 149 LIGLGAIGQHV 159
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/124 (29%), Positives = 64/124 (51%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
AA ++LK++ G ++ + +GI + NTP + AE+ V L ++A+R
Sbjct: 60 AAASRLKVIGRAGIGVDNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAA 119
Query: 436 LDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
+ G+WE + +G++L T G+IGLG +G+ V +RL+G D+ Y K
Sbjct: 120 TASTKAGKWEKS--RFMGRELAGKTAGVIGLGNVGRLVAQRLAGLDMKVVAYDPFINKDR 177
Query: 616 AKAL 627
A +L
Sbjct: 178 AISL 181
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 68.1 bits (159), Expect = 2e-10
Identities = 43/119 (36%), Positives = 64/119 (53%)
Frame = +1
Query: 199 GCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPA 378
G ALV + P++ +L AA L+IV+ AG + + E R +G+ + +PA
Sbjct: 52 GAQALVLRGSKPVSAAVLRAAPA-LRIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPA 110
Query: 379 VAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVK 555
VAE A+ L+L+ R+ + QVR G W G+D R STVGI+G G IG+A +
Sbjct: 111 VAEHALALMLALVRQLPQLDQQVRAGGW--AGSNWQGRDFRGSTVGIVGYGAIGRATAQ 167
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 68.1 bits (159), Expect = 2e-10
Identities = 40/143 (27%), Positives = 74/143 (51%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
R+E+LK I ++ S I +I+D A +LKI++ G + + + + +GI++
Sbjct: 33 RDELLKKIGDYDIIIVRSRTKIDRDIIDNA-KRLKIIARAGIGTDSIDVDYAQEKGIKIV 91
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
P + +V E+ V + A+R+ + ++ R+ + F K+ G +L T+GIIG G
Sbjct: 92 YAPGSSTESVVELTVAFAVIAARQIIKGVENTRKND----FTKLKGIELSGKTLGIIGYG 147
Query: 532 GIGQAVVKRLSGFDVARFIYSGH 600
IG+A+ S F+V Y +
Sbjct: 148 RIGRAIANAFSVFNVRSIAYDAY 170
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 67.7 bits (158), Expect = 2e-10
Identities = 42/142 (29%), Positives = 74/142 (52%), Gaps = 1/142 (0%)
Frame = +1
Query: 205 SALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVA 384
+A++ + + + ++ DAA L +V AG N + RG+ + N P S AVA
Sbjct: 42 AAILVVRSKQVQADVFDAA-PGLSLVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVA 100
Query: 385 EVAVGLLLSASRRFTENLDQVRRGEWE-IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRL 561
E+A+GL+++ RR +N+ +R G+W+ F + Q L T+G+ G+G IG+ V +R
Sbjct: 101 ELAIGLVVALDRRIPDNVALLRAGKWDKKTFSE--AQGLYGRTLGVAGVGSIGREVARRA 158
Query: 562 SGFDVARFIYSGHREKPEAKAL 627
+ +S + +AK L
Sbjct: 159 QALGMRVVAWSRSLDDRQAKLL 180
>UniRef50_A5V984 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Sphingomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 309
Score = 67.7 bits (158), Expect = 2e-10
Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 2/140 (1%)
Frame = +1
Query: 205 SALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVA 384
SAL+ + E+++ +L +++ + GY+ + +RARGIQ+ + + + VA
Sbjct: 43 SALIMAGEFRLPPELVERM-PKLGLIACFTVGYDGVDVAAVRARGIQVCHAHDANNEDVA 101
Query: 385 EVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS 564
+ A+G++L+ RR +R GEW+ G + G L + +GI+GLG IG AV +R
Sbjct: 102 DHAIGMILAERRRIFSGDRMLRAGEWKPGAKLITG-SLDGARIGIVGLGSIGAAVARRA- 159
Query: 565 GFDVARF--IYSGHREKPEA 618
DV R + G KP+A
Sbjct: 160 --DVMRMETRWWGPNPKPDA 177
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 67.7 bits (158), Expect = 2e-10
Identities = 53/173 (30%), Positives = 78/173 (45%), Gaps = 2/173 (1%)
Frame = +1
Query: 79 YPPTALKILEDHFTVL-QSRYLNF-GQEGSTLGREEILKLIPGCSALVWISNLPITNEIL 252
YP L + +H +L Q L F E + +E+I I + S I E +
Sbjct: 24 YPMKVLHVDTNHPLLLKQFEVLGFKNDEDYSSSKEQIEHRIGEYDGITIRSRFTIDKEFI 83
Query: 253 DAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTE 432
A LK + V AG + + + + I L P AV E +G+LLS +
Sbjct: 84 KKA-KNLKFIGRVGAGLENIDVAYAKKKNIFLAAAPEGNRNAVGEHTLGMLLSLFNNLNK 142
Query: 433 NLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+VR G+W+ ++ G +L TVGIIG G +G+A K+L GFDV Y
Sbjct: 143 ANLEVRNGKWDREGNR--GVELDGKTVGIIGYGNMGKAFAKKLRGFDVEVLCY 193
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 67.3 bits (157), Expect = 3e-10
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 4/179 (2%)
Frame = +1
Query: 49 NLKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISN 228
++ VLV++ Y K LE+ F + Y ++ ++G +E+++L+ +A I+
Sbjct: 11 SMTVLVTA-PYNEEGRKELENLFGSVA--YQSWKEQGRAYREDELIQLLKATNATGLITE 67
Query: 229 LPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLL 408
L + + A+ +L V ++ + RGI + TP + AVAE+ +G ++
Sbjct: 68 LDQVTDSVFASVPELSFVGVCRGMPSNVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVI 127
Query: 409 SASRRFTENLDQVRRGEWEI----GFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFD 573
S R + + ++ GEW+ + K G +L TVG+IG G +GQ + K L+ FD
Sbjct: 128 SFLRHTSASNQWLKDGEWDSDYLQAYVKFKGNELTGKTVGMIGFGAVGQRIAKLLTAFD 186
>UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;
Leuconostocaceae|Rep: 2-oxo-4-phenylbutanoate reductase
- Oenococcus oeni (Leuconostoc oenos)
Length = 306
Score = 67.3 bits (157), Expect = 3e-10
Identities = 42/123 (34%), Positives = 64/123 (52%)
Frame = +1
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
P+ IL LKIV+ GY++ N E+ + + +TNTP + AVAE A+ +L
Sbjct: 51 PVDKHILSQL-PDLKIVARYGVGYDNVNLEDASQQHVIVTNTPGANATAVAETALMHMLM 109
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+ R F + + GE + GQ++ +GIIG G IGQ V + L+GF+V Y
Sbjct: 110 SGRLFYQERQSI-TGETDA---PAKGQEVSHKKIGIIGFGAIGQKVDELLTGFNVEVLAY 165
Query: 592 SGH 600
+ H
Sbjct: 166 ARH 168
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 67.3 bits (157), Expect = 3e-10
Identities = 46/168 (27%), Positives = 85/168 (50%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLP 234
+VLVS +D P A++IL++ + + L +++ +++ L S
Sbjct: 4 RVLVS-DDLSPEAVRILQEAGLEVDVKV--------GLKPDQLERIVGDYDGLAVRSATK 54
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+T ++LD A +LK++ G ++ + RG+ + NTP S VAE+A+ ++L+
Sbjct: 55 VTAQLLDKAA-RLKVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILAL 113
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
SR V+ G+WE + G +L T+G++G+G IG +V R
Sbjct: 114 SRHVAAATGSVKAGKWE--KKRFQGHELAGRTLGVVGIGNIGSVLVAR 159
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 67.3 bits (157), Expect = 3e-10
Identities = 42/150 (28%), Positives = 83/150 (55%), Gaps = 1/150 (0%)
Frame = +1
Query: 181 ILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTP 360
+++ + C A++ + IT +++ AG +LK++S G N+ + + IQ+TN P
Sbjct: 37 LIEEVKDCDAIL-VRMANITEKVI-RAGKKLKVISRFGVGVNNVDIKTASELSIQITNAP 94
Query: 361 NVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIG 540
VAE +GL+++ +++F +R+G +++ +LG DL +GI+GLG IG
Sbjct: 95 ESNKNTVAEYTMGLIIALAKKFFLYDRGLRKGNFKV--RDILGIDLEGKVLGIVGLGSIG 152
Query: 541 QAV-VKRLSGFDVARFIYSGHREKPEAKAL 627
+ + +K GF + + H ++ E+K+L
Sbjct: 153 KLLALKASKGFGMKVIGFKRHIDE-ESKSL 181
>UniRef50_A5FIN4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Bacteroidetes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Flavobacterium johnsoniae UW101
Length = 325
Score = 67.3 bits (157), Expect = 3e-10
Identities = 50/192 (26%), Positives = 89/192 (46%), Gaps = 2/192 (1%)
Frame = +1
Query: 52 LKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNL 231
+ V ++ N P L++L++ + L + L RE+ +K+ L+ +
Sbjct: 1 MNVFINKN-IPEAGLRLLQE-----KGINLTINPTENVLSREDFIKICQKNDVLLNVGTQ 54
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
+E LK ++ S G++ N +R I + NTP+VLS A ++V+ L+ S
Sbjct: 55 NFFDEDFFQQCPNLKGIALFSVGFDSVNIPSANSRKIPIGNTPDVLSRATSDVSFLLMQS 114
Query: 412 ASRRFTENLDQVRRGEWEIGFDKV--LGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARF 585
+R+ N ++ +W FD + LGQ+L T+GI GLG IG + ++
Sbjct: 115 VARKSFFNHKRILNNDWG-SFDPLANLGQELYGKTLGIFGLGRIGFKMAQKCKAAFGMNI 173
Query: 586 IYSGHREKPEAK 621
IY K +A+
Sbjct: 174 IYHNRSRKEDAE 185
>UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase,
putative; n=1; Filobasidiella neoformans|Rep:
Glycerate-and formate-dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 344
Score = 67.3 bits (157), Expect = 3e-10
Identities = 39/109 (35%), Positives = 62/109 (56%)
Frame = +1
Query: 295 AGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGF 474
AGY+ + L A G L+NTPN ++ A A++ + L+L+A R E VR G+W G
Sbjct: 96 AGYDDVDYPWLAANGCYLSNTPNAVTEATADMGILLVLAAVRGLYEAEVSVRAGQWRKGI 155
Query: 475 DKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
+ L D + T+G IGLG IG+++ K+ +++ + +Y H KP K
Sbjct: 156 E--LTDDPTEMTIGFIGLGAIGKSMAKKTKPWNM-KILY--HNRKPLPK 199
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 66.9 bits (156), Expect = 4e-10
Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 1/127 (0%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E++DA G L+I+S + G++H + + +GI ++N+P + AE+ L+L+AS+R
Sbjct: 59 EMIDA-GENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKR 117
Query: 424 FTENLDQVRRGEW-EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGH 600
VR GEW + + G L+ ST+GI G+G IG V F + +Y+
Sbjct: 118 LAFYDSIVRSGEWIDPSEQRYQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMT-VVYNDV 176
Query: 601 REKPEAK 621
PE K
Sbjct: 177 YRLPEDK 183
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 66.9 bits (156), Expect = 4e-10
Identities = 40/127 (31%), Positives = 63/127 (49%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
+ ++ + G + ++ S P T E+L TQ+++VS V GY+ N + I +
Sbjct: 37 DHLVAALDGAAGVI-CSTEPYTAEVLSR--TQVRVVSRVGVGYDSVNVPAATEQNIAVCR 93
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP L +V E +G++L+ R QVR G+W D+ G T+GIIG G
Sbjct: 94 TPGTLHQSVVEHTIGMILAIYRNVISQNKQVRAGDW----DRTAGPRAYGKTLGIIGYGV 149
Query: 535 IGQAVVK 555
IG+ V K
Sbjct: 150 IGKEVAK 156
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 66.9 bits (156), Expect = 4e-10
Identities = 38/154 (24%), Positives = 71/154 (46%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L EE+ I C AL+ S ++ E+ +A+ +LK+V G ++ + G
Sbjct: 140 LSPEELCTKISLCDALIVRSGTKVSREVFEASSGRLKVVGRAGVGIDNVDLAAATEHGCL 199
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P + A AE + LL + +R + V+ G+W+ +K +G L T+ ++G
Sbjct: 200 VVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQ--RNKYVGVSLVGKTLAVMG 257
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G +G V +R G + + + A+A+
Sbjct: 258 FGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAI 291
>UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome C of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 339
Score = 66.9 bits (156), Expect = 4e-10
Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 3/119 (2%)
Frame = +1
Query: 244 EILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRR 423
E++ + LK ++ GY+ + +EL RGIQL+N P++++ + A++ + L+L A R
Sbjct: 69 ELISHFPSSLKYIAHQGTGYDQIDVDELNKRGIQLSNCPDIVTKSTADMNIFLMLGAMRN 128
Query: 424 FTENLDQVRRGEWE---IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
F + G+W +G G +GIIG+G IG+AV R F + +Y
Sbjct: 129 FEAGRRNLIAGKWPAGGLGAGVEAGWAPSRKVLGIIGMGNIGRAVRDRAVSFGFEKIVY 187
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 66.9 bits (156), Expect = 4e-10
Identities = 42/154 (27%), Positives = 72/154 (46%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
+G E +L I +ALV S + + +AA + L IV G ++ + + G+
Sbjct: 34 IGDEALLNTITDVNALVVRSGTDVNEAVFEAA-SDLIIVGRAGIGVDNIDIDAATEHGVI 92
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N P A AE V + + +R + ++R GEW + LG ++ T+G++G
Sbjct: 93 VANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTGEW--AKSEYLGTEVNGKTLGVVG 150
Query: 526 LGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
LG +GQ V KRL + Y + + A+ L
Sbjct: 151 LGRVGQEVAKRLESLGMDLVAYDPYISEDRAERL 184
>UniRef50_Q47748 Cluster: D-specific alpha-keto acid dehydrogenase;
n=33; Bacteria|Rep: D-specific alpha-keto acid
dehydrogenase - Enterococcus faecalis (Streptococcus
faecalis)
Length = 323
Score = 66.9 bits (156), Expect = 4e-10
Identities = 43/112 (38%), Positives = 59/112 (52%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
+K +ST S G NH + GI + T +VA+ A+ L+L A R + V
Sbjct: 73 VKYISTRSIGCNHIDTTAAERMGISV-GTVAYSPDSVADYALMLMLMAIRGAKSTIHAVA 131
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
+ + + D V G++LRD TVG+IG G IGQAVVKRL GF Y R+
Sbjct: 132 QQNFRL--DCVRGKELRDMTVGVIGTGHIGQAVVKRLRGFGCRVLAYDNSRK 181
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 66.5 bits (155), Expect = 5e-10
Identities = 36/116 (31%), Positives = 68/116 (58%), Gaps = 2/116 (1%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
I+ +++D+ LK+++T S G++H + ++GI + N P+ +V+E A+ L+L+
Sbjct: 55 ISKDVIDSL-PDLKLIATRSTGFDHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLAL 113
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIG--QAVVKRLSGFDV 576
+R+ E +D V +G ++ + G +L T+G+IG G IG A++ R G DV
Sbjct: 114 ARKLRETIDNVEKGVYKT--SNLRGIELAGKTLGVIGTGRIGARTALLARCFGMDV 167
>UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putative -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 317
Score = 66.5 bits (155), Expect = 5e-10
Identities = 37/129 (28%), Positives = 64/129 (49%)
Frame = +1
Query: 193 IPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLS 372
+P A+ ++NE ++ + L I++ G + + R R I +T TP VL+
Sbjct: 46 LPSIRAVATGGGAGLSNEWMEKLPS-LGIIAINGVGTDKVDLARARRRNIDVTTTPGVLA 104
Query: 373 PAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVV 552
VA++ + L+L+ RR + VR G W G LG + +G++GLG IG+A+
Sbjct: 105 DDVADLGIALMLAVLRRVGDGDRLVREGRWAAGEQLPLGHSPKGKRIGVLGLGQIGRALA 164
Query: 553 KRLSGFDVA 579
R F ++
Sbjct: 165 SRAEAFGMS 173
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 66.5 bits (155), Expect = 5e-10
Identities = 50/169 (29%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = +1
Query: 55 KVLVSSNDYPPTALKILEDHFTVLQSRYL-NFGQEGSTLGREEILKLIPGCSALVWISNL 231
+VLVS PTA++I +D + YL + G++ +E++L++I L S
Sbjct: 9 RVLVSDK-LSPTAVQIFKDRGVDVD--YLPDLGKD-----KEKLLEVIGEYDGLAIRSAT 60
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
+T +++ AA +LK+V G ++ + RGI + NTP S AE A+ L+ +
Sbjct: 61 KVTEKLI-AAAKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFA 119
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
+R+ E R G+WE ++ +G ++ T+G++G G IG V R
Sbjct: 120 VARQLPEADTSTRAGKWE--KNRFMGVEITGKTLGVVGCGNIGSIVATR 166
>UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3;
Bacteria|Rep: Glycerate dehydrogenase - Treponema
denticola
Length = 322
Score = 66.5 bits (155), Expect = 5e-10
Identities = 46/155 (29%), Positives = 80/155 (51%), Gaps = 4/155 (2%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE+L+ A++ + + + EI+D+ +LK + ++ GYN + E RA+ I +TN
Sbjct: 40 EELLERCKEADAVL-TNKVVFSKEIMDSL-PRLKYIGVLATGYNVVDIEAARAKNICVTN 97
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIG----FDKVLGQDLRDSTVGII 522
P+ + +VA++ L+ E+ D+V G+W + ++L D T+GI+
Sbjct: 98 IPSYSTDSVAQLVFALIFHFYWHVKEHSDEVMGGKWSASPHFCYHSFDIRELSDKTMGIV 157
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G G IGQAV K ++ + IY +R K K L
Sbjct: 158 GFGNIGQAVAKIALAMNM-KVIYF-NRSKKNIKGL 190
>UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3;
Gammaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pseudomonas fluorescens
(strain PfO-1)
Length = 322
Score = 66.5 bits (155), Expect = 5e-10
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
AA LKI+ + AGY + + RG+ +TN V + +VA+ A+ +LL+ R
Sbjct: 63 AALPALKIICVIGAGYEQVDLQAASDRGLTVTNGAGVNASSVADHAMAMLLALVRDIPRC 122
Query: 436 LDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLS-GFDV 576
VRRGEW K++ L +GI+GLG +G A+ KR GFD+
Sbjct: 123 DGAVRRGEW----PKIMRPSLAGKRLGILGLGAVGMAIAKRAGLGFDM 166
>UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep: Lactate
dehydrogenase related enzyme - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC BAA-365)
Length = 316
Score = 66.5 bits (155), Expect = 5e-10
Identities = 44/140 (31%), Positives = 68/140 (48%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE+ K AL+ I+N + E++ A LK +S G +H + E + + I ++N
Sbjct: 41 EELKKRSEDADALI-IANHLLPGEVI-RADKNLKFISVAFVGIDHVDLEACKEKKINISN 98
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
T + AVAE+A+GL L R+ + + V+ GE + G G +L TVGI+G G
Sbjct: 99 TGGYCNDAVAELAIGLTLDCLRKISAGNEAVQAGEGKGGLQ---GHELAGKTVGIVGTGA 155
Query: 535 IGQAVVKRLSGFDVARFIYS 594
IG + F YS
Sbjct: 156 IGCRTAEIFKAFGCKLIGYS 175
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 66.1 bits (154), Expect = 6e-10
Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 3/133 (2%)
Frame = +1
Query: 214 VWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVA 393
V + P NE+ DA + +++ G ++ N +GI TNTP L +VAE A
Sbjct: 48 VIVGGAPYRNELYDAV-PKGGVIARFGIGCDNINLPRAAEKGIYCTNTPGALEQSVAECA 106
Query: 394 VGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQ---AVVKRLS 564
+G++L A+R+F D R G W+ G +L T+ +IG G IG A+ K
Sbjct: 107 IGMILLAARQFIAAADDCRNGLWQ----PQTGCELAGKTLAVIGCGAIGSRVAAIAKNGF 162
Query: 565 GFDVARFIYSGHR 603
G V I S R
Sbjct: 163 GMSVTGVIRSAPR 175
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 66.1 bits (154), Expect = 6e-10
Identities = 38/122 (31%), Positives = 63/122 (51%)
Frame = +1
Query: 247 ILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRF 426
+LDA +++ +V+ G++ + RGI + N P + AVA+ VG +L R +
Sbjct: 67 LLDAM-PNCRLIQSVAVGFDGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHY 125
Query: 427 TENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
+V +G W G + + G+DL TV I+G G IG+AV +RL GF ++
Sbjct: 126 AAGHRKVEQGGW--GPEGLRGRDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPFPS 183
Query: 607 KP 612
+P
Sbjct: 184 EP 185
>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Pelobacter propionicus (strain DSM 2379)
Length = 318
Score = 66.1 bits (154), Expect = 6e-10
Identities = 39/129 (30%), Positives = 66/129 (51%), Gaps = 3/129 (2%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EEI + G +V LP+ E++ +K++ GYN+ + R+RGI + N
Sbjct: 38 EEIPSRVEG-QTIVITKELPLGRELIHCFPASVKLICEAGTGYNNIDIAAARSRGIGVCN 96
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQ---DLRDSTVGIIG 525
P+ + AVA++A+ +L+ S + +RRG + F K L +L T+G+IG
Sbjct: 97 VPSYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLD-NFQKSLQLPHFELNGKTLGVIG 155
Query: 526 LGGIGQAVV 552
G IG+ V+
Sbjct: 156 FGEIGRRVI 164
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 66.1 bits (154), Expect = 6e-10
Identities = 37/128 (28%), Positives = 65/128 (50%)
Frame = +1
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
P E+L LK + AGY++ + +GI +++TP ++ A A+V + L++
Sbjct: 64 PFDAELLSVLPKSLKYICHNGAGYDNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIG 123
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
A R+ L +R G+W+ LG D + +GI+G+GGIG+ + R F + +
Sbjct: 124 ALRQAYIPLSALRAGQWQ--GKTTLGHDPQGKVLGILGMGGIGREMANRARAFGMKIQYH 181
Query: 592 SGHREKPE 615
+ R PE
Sbjct: 182 NRSRLSPE 189
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 65.7 bits (153), Expect = 9e-10
Identities = 36/128 (28%), Positives = 69/128 (53%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L EI+ ++P A++ S +T +I+ A G+QLKI+ G ++ + +GI
Sbjct: 58 LSEAEIIDIVPEYDAIMLRSATKVTEKIIQA-GSQLKIIGRAGVGVDNIDVPAATRQGIV 116
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ N+P + A AE A+ ++++ +R + V+ +WE + +G ++ T+G++G
Sbjct: 117 VVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWE--RKQFIGTEVYKKTLGVVG 174
Query: 526 LGGIGQAV 549
LG IG V
Sbjct: 175 LGKIGSHV 182
>UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4;
Leptospira|Rep: Phosphoglycerate dehydrogenase -
Leptospira interrogans
Length = 332
Score = 65.3 bits (152), Expect = 1e-09
Identities = 35/113 (30%), Positives = 65/113 (57%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
LKI+S V G + + RGI + TP+ ++ AVAE+ +GL++S++R+ +++
Sbjct: 72 LKIISRVGIGLDSVPLNLCKERGIAVAYTPDAVTMAVAELTIGLMISSTRKVFLAHQELK 131
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREK 609
G W + G+ L +ST+GI+G+G +G V++ LS F + + ++K
Sbjct: 132 TGGW----SRFTGKRLGESTIGIVGVGRVGLNVIRILSEFRPKMILINDLKDK 180
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 65.3 bits (152), Expect = 1e-09
Identities = 46/170 (27%), Positives = 80/170 (47%)
Frame = +1
Query: 97 KILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLK 276
+ +D F LQ ++ F S + L+ + AL+ S I E+L A QL+
Sbjct: 10 RFAQDSFLYLQ-QHSQFEVVRSDNPQHLPLEHLVSAHALIIRSRTKIDEELLKKA-RQLQ 67
Query: 277 IVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRG 456
++ T ++G++H + E + G+ + +TP + A++ GL+LS V+ G
Sbjct: 68 LIVTCTSGFDHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHKMVKAG 127
Query: 457 EWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
EW D++ G +L GI+GLG IG V + F + Y ++E
Sbjct: 128 EW--NRDQITGIELAGRNYGIVGLGRIGSRVAELAQAFGMNVVAYDPYQE 175
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 65.3 bits (152), Expect = 1e-09
Identities = 43/135 (31%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
Frame = +1
Query: 178 EILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNT 357
E+ +I C ++ SN +T +L+ + +LK + G ++ + +GI + NT
Sbjct: 43 ELDAVIKMCDGVIVRSNTKLTAPVLEKS-EKLKAICRAGVGVDNIDVPAATKKGIVVMNT 101
Query: 358 P--NVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
P N++S AE + LL S SR + V+ G+WE K GQ L T GIIGLG
Sbjct: 102 PAGNIIS--TAEHTIALLCSLSRFVPQACASVKEGKWE--KKKFTGQQLTGKTFGIIGLG 157
Query: 532 GIGQAVVKRLSGFDV 576
+G+ V KR + ++
Sbjct: 158 RVGRQVAKRAAALEM 172
>UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridium
botulinum|Rep: D-lactate dehydrogenase - Clostridium
botulinum (strain ATCC 19397 / Type A)
Length = 336
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/117 (32%), Positives = 65/117 (55%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
+K ++T +AG N+ + + + GI + N P +V+E +GL LS +R+ L +V
Sbjct: 74 IKYLATRTAGVNNIDFDAAKEFGINVANVPAYSPNSVSEFTIGLALSLTRKIPFALKRVE 133
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAK 621
+ +G ++G +LR+ T+G+IG G IG V++ SGF + + I E EAK
Sbjct: 134 LNNFALG--GLIGVELRNLTLGVIGTGRIGLKVIEGFSGFGMKKMIGYDIFENEEAK 188
>UniRef50_A0IKR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14;
Enterobacteriaceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Serratia proteamaculans 568
Length = 316
Score = 65.3 bits (152), Expect = 1e-09
Identities = 41/133 (30%), Positives = 72/133 (54%)
Frame = +1
Query: 208 ALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAE 387
A+V ++ +T +L+ QL +++ G + + R R I +T T L+ VA+
Sbjct: 51 AVVTRGDIGVTTPVLEQL-PQLGLIAVFGVGTDAIDLNYTRQRDIAVTITSGALTEDVAD 109
Query: 388 VAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSG 567
+A+GLLL+ +R+ N VR G W + L + +GI G+G IG+A+ +R +G
Sbjct: 110 MALGLLLATARQLCFNDRFVRDGHW-LQKAPGLSVQVSGKRLGIFGMGNIGRAIAQRAAG 168
Query: 568 FDVARFIYSGHRE 606
F++ R Y+ HR+
Sbjct: 169 FNM-RIQYASHRQ 180
>UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 327
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/118 (32%), Positives = 62/118 (52%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
+T E L A +LK +S GY++ + G+ +T P++L+ AE+A+GL ++A
Sbjct: 58 VTKESLLNA-PRLKTISCALKGYDNFDLRACAQAGVSVTFVPDLLTEPTAELAIGLAIAA 116
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFI 588
R + D R + + G L S +IGLG +GQA++ RL+GF AR +
Sbjct: 117 GRNVLQG-DAATRAGYSGWRPALYGTGLHGSVASVIGLGKVGQAILARLAGFGCARLL 173
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 64.9 bits (151), Expect = 1e-09
Identities = 38/151 (25%), Positives = 75/151 (49%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE++ +I AL+ S +T +I++A G +L+++ G ++ + + GI + N
Sbjct: 33 EELISIIGEYDALLVRSQTQVTADIINA-GKKLQVIGRAGVGVDNIDLKTATGNGIIVVN 91
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
P + + E + L+L+ +R ++ G+W+ ++ +G +L+ T+GI+GLG
Sbjct: 92 APTGNTISATEHTLALMLAMARHIPRANASLKSGQWKR--NEFVGSELKGKTLGIVGLGN 149
Query: 535 IGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
IG + KR ++ Y AK L
Sbjct: 150 IGSEIAKRALALEMRVIGYDPFISMERAKKL 180
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/126 (31%), Positives = 63/126 (50%)
Frame = +1
Query: 193 IPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLS 372
I AL+ + + E++DAA +LKI++ AG ++ + E +GI + TP+ S
Sbjct: 41 IQNTRALIVRNQTKVDRELIDAA-PELKIIARAGAGLDNVDTEYAHEKGIVVCFTPDANS 99
Query: 373 PAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVV 552
+VAE+ +GL+L+ R+ E G W K G +L + G+IGLG IG
Sbjct: 100 LSVAELTIGLMLALMRKIPEARQDTLTGGW--NRLKFTGTELYGKSFGLIGLGRIGSFTA 157
Query: 553 KRLSGF 570
R F
Sbjct: 158 TRAKAF 163
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/133 (29%), Positives = 71/133 (53%), Gaps = 1/133 (0%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E++ + G LV + + + + +++AA + L++V +G N + E RG+ + N
Sbjct: 33 EQLPDRLTGREVLV-VRSTAVPSAVIEAADS-LRLVIRAGSGTNTIDCESAAERGVHVCN 90
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWE-IGFDKVLGQDLRDSTVGIIGLG 531
P + AVAE+A L+L+ R +N+D +R G W+ + + G + VG++GLG
Sbjct: 91 VPGRNAIAVAELAFALMLALDRSVCDNVDDLRAGRWDKKRYSRARG--IHGRRVGVVGLG 148
Query: 532 GIGQAVVKRLSGF 570
IG A +R + F
Sbjct: 149 QIGLAFAERAAAF 161
>UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: D-3 phosphoglycerate
dehydrogenase - Bacillus sp. B14905
Length = 319
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/155 (25%), Positives = 68/155 (43%)
Frame = +1
Query: 163 TLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGI 342
T R E+ + G ++ I+N P E++D LK+++ G +H + R + +
Sbjct: 37 TTDRAELARRSEGADVIM-IANNPYPTEVIDQ-NANLKLINVAFTGVDHVGIGQARNQDV 94
Query: 343 QLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGII 522
+ N + AVAE+ +GL+L R T+ ++ + F G +++ TVG+I
Sbjct: 95 MVCNAAGYANQAVAELTIGLVLDVYRHITQGDKEIHADHFPGAFQ---GSEIKGKTVGLI 151
Query: 523 GLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
G G IG + F R P A+ L
Sbjct: 152 GTGKIGMMTARLFKAFGAKIVASDQSRRNPAAEVL 186
>UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Verminephrobacter
eiseniae EF01-2|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 317
Score = 64.9 bits (151), Expect = 1e-09
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +1
Query: 100 ILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWI-SNLPITNEILDAAGTQLK 276
++ + F V+ S G + T G +I P ++ +N + +EI AA +L+
Sbjct: 18 LVSERFEVIYSPNEKLGAD-RTNGEAQIAARGPDIRVVLTNGTNGLLASEI--AALPKLE 74
Query: 277 IVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRG 456
++STV G+ + + RGI + N AVA+ A+ +LL+A RR D VR G
Sbjct: 75 LISTVGVGFENIALDAASTRGIPVCNAAGTNDAAVADHAMAILLAAIRRLPFLNDGVRNG 134
Query: 457 EWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
W + + +GI GLG IG+ + KR SGFD+
Sbjct: 135 LWRDDIPR--PPHVSGRRMGIFGLGAIGRKIAKRASGFDM 172
>UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Acinetobacter sp. ADP1|Rep: Putative 2-hydroxyacid
dehydrogenase - Acinetobacter sp. (strain ADP1)
Length = 322
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/141 (27%), Positives = 74/141 (52%), Gaps = 4/141 (2%)
Frame = +1
Query: 211 LVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEV 390
++ IS+L I ++L LK+++ S GYNH N E LR +Q+ N AVAE
Sbjct: 51 VIIISDLIIDEQVLKN-NPNLKLLALCSTGYNHVNIELLRQHNVQVCNIRGYAGDAVAEH 109
Query: 391 AVGLLLSASRRFTENLDQVRRGEWEIG----FDKVLGQDLRDSTVGIIGLGGIGQAVVKR 558
A L++ + F++ ++ V++G W G + ++L+ T+ I+G G IG+++ ++
Sbjct: 110 AFTLMIQLIKNFSQQVEGVKQGLWGTGQSSFYLAAPMRELKGKTLTILGKGEIGESLAQK 169
Query: 559 LSGFDVARFIYSGHREKPEAK 621
F + I+S + + +
Sbjct: 170 ARAFGM-HIIFSERKNASQCR 189
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/180 (25%), Positives = 86/180 (47%)
Frame = +1
Query: 52 LKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNL 231
+KVL++ + +P +L+ F V E +L +E+ +I + L+ S
Sbjct: 13 MKVLITDSVHPQCGRLLLQHGFEVT---------EKPSLSPKELHAIIADYNILIVRSAT 63
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
+ E+L A TQL+++ G ++ + E +GI + +TP + + AE +LL+
Sbjct: 64 SLPAEVL-AKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLA 122
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
A+R + + +++G W G +L T+ +IGLG +G+ V R+ F + Y
Sbjct: 123 AARHIPQAMADLKQGNWNKHL--YAGIELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAY 180
>UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 319
Score = 64.5 bits (150), Expect = 2e-09
Identities = 38/118 (32%), Positives = 63/118 (53%), Gaps = 2/118 (1%)
Frame = +1
Query: 268 QLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQV 447
+L+++ + +GY+ + + R RGI +TN+P + +VA++A+GLL+S+ R +
Sbjct: 69 RLELICCLGSGYDGIDLDHARQRGIVVTNSPAANAASVADLAMGLLISSVRNLPAARQYL 128
Query: 448 RRGEWE--IGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPE 615
G W+ G + L +GI GLG IG V KR + FD+ Y G +PE
Sbjct: 129 EAGRWQGNAGERMPPVRGLGGRRLGICGLGAIGLNVAKRAAAFDM-EVGYHGRTARPE 185
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/123 (31%), Positives = 68/123 (55%), Gaps = 1/123 (0%)
Frame = +1
Query: 190 LIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVL 369
L+PGC+ + + + +DAAG L+ + G ++ + RGI + NTP+
Sbjct: 42 LLPGCTVAIITALIDANGAWMDAAGDALRAICRPGIGVDNIDIAAATKRGILVINTPDGP 101
Query: 370 SPAVAEVAVGLLLSASRRFTENLDQVRRGE-WEIGFDKVLGQDLRDSTVGIIGLGGIGQA 546
+ + AE AV LLL+ +++ + D+V R E W ++ G ++R T+GI+GLG IG+
Sbjct: 102 TESTAEHAVALLLALAKQVVAS-DRVLRTEGWRAA--RLRGIEVRGKTLGIVGLGRIGRR 158
Query: 547 VVK 555
V +
Sbjct: 159 VAQ 161
>UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9301|Rep: Putative
dehydrogenase - Prochlorococcus marinus (strain MIT
9301)
Length = 318
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/180 (25%), Positives = 85/180 (47%)
Frame = +1
Query: 52 LKVLVSSNDYPPTALKILEDHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNL 231
+K +V SN +++LE +F V+ + Q L E++ L ++
Sbjct: 1 MKKVVISNKVHTEVIELLEKNFEVISN------QNDKPLTYEKLKFLCKDAHGVMVFMPD 54
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
I LD + L+I+S G+++ + EE R I+ T P++L+ AE+ +GLL+
Sbjct: 55 RIDKNFLDNS-KNLEIISGALRGFDNIDLEECIKRNIKFTMIPDLLASPTAELTLGLLIG 113
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
SR + VR +++ K + V ++G+G +G V +++ GF+V F Y
Sbjct: 114 LSRNLLIGDEYVRSEKFKGWEPKFFSNGIEGKNVCLLGMGKLGVEVARKIKGFNVKLFYY 173
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/128 (28%), Positives = 65/128 (50%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
EE+ +I AL+ S +T +IL+A +LK V+ G ++ + G+ + N
Sbjct: 36 EELKSIIGQYDALIIRSATKVTADILEAGAPKLKAVARAGIGLDNVDIPAATKHGVAVMN 95
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
TP AE + ++++ +R + +R G+WE K+ G+++ + T+G+IG G
Sbjct: 96 TPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSGQWE--KKKLQGREVFNKTLGVIGFGK 153
Query: 535 IGQAVVKR 558
IG V R
Sbjct: 154 IGSIVADR 161
>UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Glyoxylate reductase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 354
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 4/143 (2%)
Frame = +1
Query: 193 IPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLS 372
+ G A+V ++P + E++ +L+ ++ AGY+ +P L G+ LTNTP +
Sbjct: 54 LAGVDAVVSFGHIPFSAELVRQV-PRLRHIARFGAGYDGIDPVALAREGVVLTNTPGAVR 112
Query: 373 PAVAEVAVGLLLSASRRFTENLDQVRRGEW--EIGFDKVLGQDLRDSTVGIIGLGGIGQA 546
+A + LLL+ + R EN G+W E G + +G D R TVGI+G G +G
Sbjct: 113 RPLALSGLTLLLACAHRLLENHRVTVSGKWALERGAHRGIGVDGR--TVGILGFGSVGSE 170
Query: 547 VVKRLS--GFDVARFIYSGHREK 609
+ L+ G +V SG E+
Sbjct: 171 LAGMLAPLGVEVIATTRSGRSER 193
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/142 (27%), Positives = 68/142 (47%)
Frame = +1
Query: 166 LGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQ 345
L +EE++ IP L+ S ++ +++ A G LKI+ G ++ + G+
Sbjct: 36 LSKEELVSEIPKYDGLIVRSATKVSEDVIKA-GKNLKIIGRAGTGVDNIDTVAASLHGVL 94
Query: 346 LTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIG 525
+ NTP + + AE L+ S +R + + G+WE + +G +L T+ IIG
Sbjct: 95 VMNTPGGNTLSAAEHTCALISSLARHIPQASASTKEGKWE--RKQFMGNELFGKTLAIIG 152
Query: 526 LGGIGQAVVKRLSGFDVARFIY 591
LG IG+ V R+ + V Y
Sbjct: 153 LGRIGREVALRMQSYGVKTIGY 174
>UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 353
Score = 64.5 bits (150), Expect = 2e-09
Identities = 34/126 (26%), Positives = 67/126 (53%), Gaps = 2/126 (1%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARG--IQLTNTPNVLSPAVAEVAVGLLL 408
+ E+++ L+ ++ AGY+ + + AR + ++N P ++ A A+V + L++
Sbjct: 84 VDEELVNVLPNSLRYLAHCGAGYDQIDVDACSARSPPVLVSNVPTAVNDATADVNMFLII 143
Query: 409 SASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFI 588
A R F ++ +R G+W+ LG D + +GI+G+GGIG+ + K+ F + I
Sbjct: 144 GALRNFNTSILALREGKWKGQPPPKLGHDPQGKVLGILGMGGIGRNLKKKAEAFGL-EII 202
Query: 589 YSGHRE 606
Y R+
Sbjct: 203 YHNRRK 208
>UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase;
n=10; Bacteria|Rep: Possible phosphoglycerate
dehydrogenase - Clostridium acetobutylicum
Length = 324
Score = 64.1 bits (149), Expect = 3e-09
Identities = 33/129 (25%), Positives = 70/129 (54%), Gaps = 4/129 (3%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
IT+++++ +LK + ++ GYN + E + +GI +TN P + +V ++++ L+L
Sbjct: 60 ITSKVIEKL-PKLKYIGVLATGYNVVDLEFAKKKGIVVTNIPQYSTSSVVQMSMALILEI 118
Query: 415 SRRFTENLDQVRRGEW----EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVAR 582
++ V++G+W + + K +L T+G++G G IG+A+ K +
Sbjct: 119 CGHVGQHNASVKKGDWQNCADFSYLKYPIIELSGKTIGLVGYGSIGKAMQKAAEALGMKV 178
Query: 583 FIYSGHREK 609
F+Y+ H +K
Sbjct: 179 FVYTPHPDK 187
>UniRef50_Q7UKR1 Cluster: Phosphoglycerate dehydrogenase
SerA2-putative NAD-dependent 2- hydroxyacid
dehydrogenase; n=2; Planctomycetaceae|Rep:
Phosphoglycerate dehydrogenase SerA2-putative
NAD-dependent 2- hydroxyacid dehydrogenase -
Rhodopirellula baltica
Length = 359
Score = 64.1 bits (149), Expect = 3e-09
Identities = 46/147 (31%), Positives = 77/147 (52%), Gaps = 1/147 (0%)
Frame = +1
Query: 139 LNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCN- 315
LN E G+E I +L+P + + +P+ + + AAG +L + + +AG +HC
Sbjct: 48 LNHDVEVVDAGQERIDELLPTADIFIGHAKVPVDWDRVLAAG-RLGWIQSSAAGLDHCLV 106
Query: 316 PEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQD 495
P + I +++ + +P VAE LL RR L + R + E F ++ D
Sbjct: 107 PGVIANPNIMVSSASGLFAPQVAEQTFALLFGILRRI--GLFERARPKRE--FIRLPTDD 162
Query: 496 LRDSTVGIIGLGGIGQAVVKRLSGFDV 576
LR T+GI+GLGG G+A+ +L+ +DV
Sbjct: 163 LRGKTIGIVGLGGNGRAIAAKLAPWDV 189
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 64.1 bits (149), Expect = 3e-09
Identities = 41/129 (31%), Positives = 65/129 (50%)
Frame = +1
Query: 235 ITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSA 414
IT ++L + +L++V G + + E +G+ + T + AVAE + L+L+A
Sbjct: 62 ITEKLLQES-PKLRLVHKWGIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILAA 120
Query: 415 SRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYS 594
RR +R G+W + L + L TVGI+G G IG+ V +RL GFDV +
Sbjct: 121 LRRLALADQSMREGKWIYTELRPLCRKLSGKTVGILGFGNIGRNVAQRLQGFDVEIIYHD 180
Query: 595 GHREKPEAK 621
R PE +
Sbjct: 181 PFRAPPEVE 189
>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mycobacterium gilvum
PYR-GCK
Length = 298
Score = 64.1 bits (149), Expect = 3e-09
Identities = 39/105 (37%), Positives = 54/105 (51%)
Frame = +1
Query: 256 AAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTEN 435
A +LK V G + + E R G+ + NTP V VA+ A G +L+ +R +
Sbjct: 58 AGAGKLKTVIRWGIGMDSVDHEAARRHGVTVRNTPGVFGYEVADSAFGYILNLARGYMAV 117
Query: 436 LDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
VRRGEW KV G L S +GI+G G IG+ + KR +GF
Sbjct: 118 DAAVRRGEW----PKVEGITLDGSRLGIVGFGAIGREIAKRGAGF 158
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 64.1 bits (149), Expect = 3e-09
Identities = 40/151 (26%), Positives = 73/151 (48%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTN 354
E++ I L+ + +T +I++A+G L++++ G ++ + + +GI + N
Sbjct: 35 EDLKATIGQYDGLIVRNQTKVTKDIIEASGN-LRVIARAGVGVDNIDVDAATRKGIIVVN 93
Query: 355 TPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGG 534
+P + + E + ++LS SR + G+WE +K G +L T+GIIG G
Sbjct: 94 SPGGNTISATEHTLAMMLSLSRNIPQAHKSAAAGKWE--REKFKGVELFKKTLGIIGTGK 151
Query: 535 IGQAVVKRLSGFDVARFIYSGHREKPEAKAL 627
IG V KR F +A Y + + A L
Sbjct: 152 IGTEVAKRAKAFGMAVLGYDPYLTEERAAKL 182
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/163 (25%), Positives = 80/163 (49%), Gaps = 2/163 (1%)
Frame = +1
Query: 109 DHFTVLQSRYLNFGQEGSTLGREEILKLIPGCSALVWISNLPITNEILDAA--GTQLKIV 282
D + +L F + + E++ + I +V S I E++D A G +LK++
Sbjct: 11 DKKAISNLEFLGFDVDTNHYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAIKGGKLKLI 70
Query: 283 STVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEW 462
G ++ + + GI++ NTPN S +VAE+ + + S +R ++ ++ G W
Sbjct: 71 IRGGVGVDNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLW 130
Query: 463 EIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIY 591
+ +G +L T+GIIG+G IG + K+ + + + IY
Sbjct: 131 K--KKDYVGVELEGKTLGIIGMGRIGSELAKKCTALGM-KIIY 170
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 63.7 bits (148), Expect = 3e-09
Identities = 48/127 (37%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
Frame = +1
Query: 193 IPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLS 372
I G AL+ I +T+ +D A +LKIVS GY+ + L ARGI L + S
Sbjct: 41 IAGADALL-IRTQALTSPTIDRAD-RLKIVSRHGVGYDAVDVAALNARGIALAVCGDANS 98
Query: 373 PAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGF-DKVLGQDLRDSTVGIIGLGGIGQAV 549
+VAE A L+L+A +R VRRG W G+ +++ QD+R + I+G G IGQ
Sbjct: 99 TSVAEHACMLILAAFKRALRADVAVRRGPW--GWRNQLESQDIRGRNLLILGFGRIGQHT 156
Query: 550 VKRLSGF 570
+SGF
Sbjct: 157 ATMMSGF 163
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 63.7 bits (148), Expect = 3e-09
Identities = 37/111 (33%), Positives = 60/111 (54%)
Frame = +1
Query: 238 TNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSAS 417
T E+++A+ +LKI++ G ++ + + +T+TP S AVAE LLLS +
Sbjct: 53 TREMIEAS-PRLKIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLT 111
Query: 418 RRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGF 570
RR ++V G W G ++G +L T+GI+G G IG+ V +GF
Sbjct: 112 RRIIPAANRVLAGTWAEGRGDLVGFELSGRTLGIVGFGAIGKRVATIANGF 162
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 63.7 bits (148), Expect = 3e-09
Identities = 43/130 (33%), Positives = 66/130 (50%)
Frame = +1
Query: 160 STLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARG 339
+ L R+ +L+ I L S +T ILDAA L I G N + + RG
Sbjct: 141 NALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAAPKLLGI-GCFCIGTNQVDLDYATTRG 199
Query: 340 IQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGI 519
+ + N+P + +VAE+ +G ++S SR+ T+ ++V RG W V ++R TVGI
Sbjct: 200 VAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVW--NKTHVGCYEVRGKTVGI 257
Query: 520 IGLGGIGQAV 549
+G G IG V
Sbjct: 258 VGYGHIGSQV 267
>UniRef50_Q4P4C6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 381
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/154 (30%), Positives = 69/154 (44%), Gaps = 8/154 (5%)
Frame = +1
Query: 175 EEILKLIPGC-SALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
E +L+ +PG +A+VW + ++AA +LK+VST S G + R GI +
Sbjct: 57 EWLLRQLPGADAAIVWPVAGQFGVDQINAASERLKVVSTYSVGTEAVDRVACRKAGITVG 116
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVL-------GQDLRDST 510
TP + ++AE + +LL RR V G++ VL G T
Sbjct: 117 YTPYIGDDSIAEYTIAMLLHFCRRIDYLQSIVMNGQFAASLRDVLCNPTMHCGVSPAGKT 176
Query: 511 VGIIGLGGIGQAVVKRLSGFDVARFIYSGHREKP 612
VG G G I Q ++L F VAR Y+ KP
Sbjct: 177 VGFYGFGRIAQKAAEKLLAFGVARIAYTTSTAKP 210
>UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:
Predicted protein - Ajellomyces capsulatus NAm1
Length = 316
Score = 63.7 bits (148), Expect = 3e-09
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +1
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
P E+L KI+++ SAGYN + + + I NT N +S A A++++ L+L+
Sbjct: 74 PFDEELLGPLAPHCKIIASGSAGYNEFDVDWMTRSKIWFCNTRNAVSEATADMSMFLILA 133
Query: 412 ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDV 576
+ T R G W+ G V +D R T+GI+G+G IG+ + ++ F++
Sbjct: 134 VLKNATVAERSAREGRWKDGL--VPTKDPRGLTLGIVGMGSIGKHLARKALAFNL 186
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 63.7 bits (148), Expect = 3e-09
Identities = 41/132 (31%), Positives = 69/132 (52%), Gaps = 2/132 (1%)
Frame = +1
Query: 232 PITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLS 411
P+ ++L +L+ V S GY++ + ++ GI ++N P + +VAE A+ ++LS
Sbjct: 50 PVNGDLLKKM-PRLRFVQVASIGYDNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLS 108
Query: 412 --ASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARF 585
+RF + ++R G W DL T GI+G+G IG+A+ RL F VA
Sbjct: 109 LIKDQRFLD--AEIRSGRWP---RITRSSDLMGKTFGIVGMGSIGRALAARLLPFKVA-I 162
Query: 586 IYSGHREKPEAK 621
IY+ + EA+
Sbjct: 163 IYNDTKRMSEAE 174
>UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=51;
Bacteria|Rep: 2-hydroxyacid dehydrogenase homolog -
Haemophilus influenzae
Length = 331
Score = 63.7 bits (148), Expect = 3e-09
Identities = 40/140 (28%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
Frame = +1
Query: 175 EEILKLIPGCSALVWISNLPITNEILDA-AGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
E ++L C + N + ++L+ A +KIV+ AG+N+ + + + GIQ+
Sbjct: 36 ESTVRLAEHCEVVCIFVNDNGSRKVLEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVV 95
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVGIIGLG 531
P AVAE +GL+++ +RR + R + + + ++G ++ TVG+IG G
Sbjct: 96 RVPAYSPEAVAEHTIGLMMTLNRRIHRAYQRTREANFSL--EGLIGFNMYGRTVGVIGTG 153
Query: 532 GIGQAVVKRLSGFDVARFIY 591
IG AV++ L GF + Y
Sbjct: 154 KIGIAVMRILKGFGMNILAY 173
>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Gloeobacter violaceus
Length = 310
Score = 63.3 bits (147), Expect = 5e-09
Identities = 52/155 (33%), Positives = 78/155 (50%), Gaps = 3/155 (1%)
Frame = +1
Query: 163 TLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPE--ELRAR 336
TL E++ L+PG + I + P T + AAG + ++ + V G N + RA
Sbjct: 36 TLSVAELVDLLPGFDGWI-IGDDPATRAVF-AAGVRGRLKAAVKWGVGVDNVDFAAARAL 93
Query: 337 GIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLD-QVRRGEWEIGFDKVLGQDLRDSTV 513
GI + NTP + VA+VAV + + +R T ++D +VR G W K G L TV
Sbjct: 94 GIPIANTPAMFGAEVADVAVSYVTALARE-TFSVDREVRAGGW----PKPCGVSLAGKTV 148
Query: 514 GIIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEA 618
++G G IG+A +RL ++ R I R PEA
Sbjct: 149 ALVGFGDIGKATARRLVAAEM-RVIAYDPRYVPEA 182
>UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Beggiatoa sp. PS|Rep: D-3-phosphoglycerate dehydrogenase
- Beggiatoa sp. PS
Length = 302
Score = 63.3 bits (147), Expect = 5e-09
Identities = 42/142 (29%), Positives = 76/142 (53%), Gaps = 3/142 (2%)
Frame = +1
Query: 172 REEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRARGIQLT 351
+E +L++I ++ S + + E + AA LK+V G +H +EL+ RGI
Sbjct: 31 KERLLEVIEDKDVVILKSRIELDKEAIFAA-KHLKLVVMAGIGLDHICLDELKKRGIAWF 89
Query: 352 NTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEI-GFDKVLGQDLRDSTVGIIGL 528
N P++ + VAE+ +GL LS +R+ +R E+++ +++G +L+D GI+G
Sbjct: 90 NIPDLSARGVAELVLGLTLSLARKICLGDSLLRNNEFKLWKRPELMGFNLQDRLFGIVGY 149
Query: 529 GGIGQ--AVVKRLSGFDVARFI 588
G IG+ A V + G V ++
Sbjct: 150 GKIGKEMASVAKCFGMKVQVYV 171
>UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=10; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 334
Score = 62.9 bits (146), Expect = 6e-09
Identities = 39/112 (34%), Positives = 60/112 (53%)
Frame = +1
Query: 271 LKIVSTVSAGYNHCNPEELRARGIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVR 450
L+IV+ G + + + RARGI +T TP+VL+ VA++A+GL+L R VR
Sbjct: 89 LEIVAISGIGTDAVDLDRARARGIHVTTTPDVLTDDVADMAMGLILMTLRDLGAGERIVR 148
Query: 451 RGEWEIGFDKVLGQDLRDSTVGIIGLGGIGQAVVKRLSGFDVARFIYSGHRE 606
G W + L + +GI+GLG +G+A+ +R F + Y G RE
Sbjct: 149 AGRWG-KTAQPLATQVTGKRLGIVGLGRVGRAIAQRAQAFRMP-VSYFGPRE 198
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 62.9 bits (146), Expect = 6e-09
Identities = 38/156 (24%), Positives = 79/156 (50%)
Frame = +1
Query: 157 GSTLGREEILKLIPGCSALVWISNLPITNEILDAAGTQLKIVSTVSAGYNHCNPEELRAR 336
G L +E++++ C +V P+ +++D L+ +S V G + + + + +
Sbjct: 35 GRKLTEDEVIEIAKECVGIV-AGVEPLNQKVMDNL-PNLRCISRVGVGMDSVDLDYAKQK 92
Query: 337 GIQLTNTPNVLSPAVAEVAVGLLLSASRRFTENLDQVRRGEWEIGFDKVLGQDLRDSTVG 516
GI +TNTP+ + +VAE+ + + L+ R+ + +++G W+ K +G + + VG
Sbjct: 93 GIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWK----KEIGNLMYEKKVG 148
Query: 517 IIGLGGIGQAVVKRLSGFDVARFIYSGHREKPEAKA 624
+IGLG IG+ + F + + + E A+A
Sbjct: 149 LIGLGKIGKLAASQFQAFGCSVMAFDLYPETAWAEA 184
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 633,516,792
Number of Sequences: 1657284
Number of extensions: 12807286
Number of successful extensions: 45319
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 42937
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44849
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46051731393
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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