Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30750
(674 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue acetyltrans... 142 5e-33
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 133 3e-30
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 130 4e-29
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 127 2e-28
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 127 2e-28
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 125 9e-28
UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Eugl... 124 1e-27
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 124 3e-27
UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1; ... 121 1e-26
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 120 3e-26
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 120 4e-26
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 118 1e-25
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 118 2e-25
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 116 5e-25
UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2 comp... 114 2e-24
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 112 9e-24
UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 112 9e-24
UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2; ... 111 1e-23
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 110 3e-23
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 110 3e-23
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 110 3e-23
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 109 8e-23
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 107 2e-22
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 107 2e-22
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 106 6e-22
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 105 7e-22
UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 104 2e-21
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 103 5e-21
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-21
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 103 5e-21
UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2 comp... 102 7e-21
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 102 9e-21
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 101 1e-20
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 101 1e-20
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 100 6e-20
UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding pro... 100 6e-20
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 98 1e-19
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 97 3e-19
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 97 5e-19
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 95 1e-18
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 95 2e-18
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 95 2e-18
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 94 2e-18
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 94 2e-18
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 93 4e-18
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 93 6e-18
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 93 6e-18
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 93 7e-18
UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1... 92 1e-17
UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component, d... 92 1e-17
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 90 5e-17
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 90 5e-17
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 89 7e-17
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 88 2e-16
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 88 2e-16
UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, compone... 87 3e-16
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 83 5e-15
UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 81 3e-14
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 81 3e-14
UniRef50_UPI0000E4A223 Cluster: PREDICTED: similar to dihydrolip... 80 4e-14
UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2 com... 80 4e-14
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 80 6e-14
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 78 2e-13
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 78 2e-13
UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma j... 77 4e-13
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 75 2e-12
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 75 2e-12
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 75 2e-12
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 75 2e-12
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario... 74 4e-12
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 73 8e-12
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 73 8e-12
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 72 1e-11
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 71 3e-11
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 71 3e-11
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 70 6e-11
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 70 6e-11
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 69 8e-11
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 68 2e-10
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 68 2e-10
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 67 3e-10
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 67 4e-10
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 66 6e-10
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 66 7e-10
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 66 7e-10
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 66 7e-10
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans... 66 7e-10
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 66 7e-10
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 66 1e-09
UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC ... 65 1e-09
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 65 1e-09
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 65 2e-09
UniRef50_A5CEC1 Cluster: Putative uncharacterized protein; n=6; ... 65 2e-09
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 65 2e-09
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,... 64 2e-09
UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-contain... 64 2e-09
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 64 2e-09
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 64 4e-09
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 63 7e-09
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 63 7e-09
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 63 7e-09
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 62 9e-09
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 62 1e-08
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ... 62 2e-08
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 62 2e-08
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 62 2e-08
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 62 2e-08
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 62 2e-08
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 61 2e-08
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 61 3e-08
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4... 61 3e-08
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 61 3e-08
UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide S-succinyltra... 60 4e-08
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 60 4e-08
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 60 5e-08
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 60 5e-08
UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase e... 60 5e-08
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 60 5e-08
UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase comp... 60 5e-08
UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2 comp... 60 6e-08
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario... 60 6e-08
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 60 6e-08
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 59 8e-08
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 8e-08
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 8e-08
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 59 8e-08
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 59 1e-07
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com... 58 1e-07
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;... 58 1e-07
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 58 2e-07
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 58 3e-07
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 58 3e-07
UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase co... 58 3e-07
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 58 3e-07
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 58 3e-07
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 58 3e-07
UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;... 57 3e-07
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 57 3e-07
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 57 3e-07
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 57 3e-07
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 57 3e-07
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 57 4e-07
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 56 6e-07
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 56 6e-07
UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2... 56 6e-07
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 56 6e-07
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n... 56 6e-07
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 56 6e-07
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 56 8e-07
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 56 8e-07
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 56 8e-07
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 56 1e-06
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 56 1e-06
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 56 1e-06
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 56 1e-06
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario... 55 1e-06
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 55 2e-06
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 55 2e-06
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 54 2e-06
UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n... 54 2e-06
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 54 2e-06
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 54 2e-06
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans... 54 2e-06
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 54 2e-06
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 54 3e-06
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 54 3e-06
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 54 4e-06
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ... 54 4e-06
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 54 4e-06
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 54 4e-06
UniRef50_Q1AZ52 Cluster: Catalytic domain of components of vario... 53 6e-06
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,... 53 6e-06
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 53 7e-06
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 53 7e-06
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario... 53 7e-06
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 53 7e-06
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 52 1e-05
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 52 1e-05
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 52 1e-05
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 52 1e-05
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 52 1e-05
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss... 52 1e-05
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.... 52 1e-05
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 52 1e-05
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 52 2e-05
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 52 2e-05
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 51 2e-05
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 51 2e-05
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 51 3e-05
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 51 3e-05
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 50 4e-05
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 50 4e-05
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 50 4e-05
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 50 5e-05
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ... 50 5e-05
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 50 5e-05
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 50 5e-05
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 50 7e-05
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp... 49 9e-05
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 49 9e-05
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 49 9e-05
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 49 9e-05
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 49 1e-04
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 49 1e-04
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 48 2e-04
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 48 2e-04
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 48 2e-04
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 48 2e-04
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 48 2e-04
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 48 2e-04
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 48 2e-04
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario... 48 3e-04
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ... 48 3e-04
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 48 3e-04
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 48 3e-04
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo... 48 3e-04
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 47 4e-04
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 47 4e-04
UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2... 46 6e-04
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh... 46 6e-04
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 46 8e-04
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 46 8e-04
UniRef50_Q5AGX7 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 46 0.001
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 46 0.001
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 45 0.001
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 45 0.001
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 45 0.001
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 45 0.001
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 44 0.003
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n... 44 0.004
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 44 0.004
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 44 0.004
UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase, c... 44 0.004
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su... 43 0.006
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 43 0.008
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 43 0.008
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 43 0.008
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera... 43 0.008
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera... 43 0.008
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 43 0.008
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp... 43 0.008
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=... 42 0.018
UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue succinyltra... 42 0.018
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra... 42 0.018
UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1; M... 41 0.032
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 41 0.032
UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1; ... 41 0.032
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 41 0.032
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 40 0.042
UniRef50_Q14PE3 Cluster: Hypothetical dihydrolipoamide acetyltra... 40 0.042
UniRef50_Q6CL94 Cluster: Similar to sp|Q02542 Saccharomyces cere... 40 0.055
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 40 0.073
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 40 0.073
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf... 39 0.13
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario... 38 0.17
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ... 38 0.29
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 38 0.29
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 38 0.29
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 36 0.90
UniRef50_A7SUF4 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.6
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 35 1.6
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 35 2.1
UniRef50_UPI00005103B2 Cluster: COG0508: Pyruvate/2-oxoglutarate... 34 3.6
UniRef50_A7MGN4 Cluster: Putative uncharacterized protein; n=2; ... 33 4.8
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 33 4.8
UniRef50_Q29DX8 Cluster: GA11104-PA; n=3; Diptera|Rep: GA11104-P... 33 4.8
UniRef50_A6FPU0 Cluster: Putative aminopeptidase; n=1; Roseobact... 33 6.3
>UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=6; Bilateria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Caenorhabditis elegans
Length = 507
Score = 142 bits (345), Expect = 5e-33
Identities = 80/184 (43%), Positives = 111/184 (60%), Gaps = 3/184 (1%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GRV ASP A++LA + L G G+G G + + DL
Sbjct: 218 GRVSASPFAKKLAAENGLDLSGVSGSGPGGRILASDLSQAPAKGATSTTTQAVSGQD--- 274
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD- 474
+ D+PLS MR+TIAKRLT +K +IPHY L+ + ++ L +R+ +N LA +
Sbjct: 275 ----YTDIPLSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQ 330
Query: 475 -VKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
K+S+NDFIIKA A AC+RVP NS+WM+SFIR+ +VDVSVAV+TP GLITP + NA
Sbjct: 331 ATKISINDFIIKASALACQRVPEANSYWMDSFIRENHHVDVSVAVSTPAGLITPIIFNAH 390
Query: 652 SRGI 663
++G+
Sbjct: 391 AKGL 394
>UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=46; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Homo sapiens (Human)
Length = 614
Score = 133 bits (322), Expect = 3e-30
Identities = 78/185 (42%), Positives = 105/185 (56%), Gaps = 4/185 (2%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GRV+ P+A++LA K I L +GTG G + D+
Sbjct: 320 GRVFVDPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGM 379
Query: 298 XXX---TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEK 468
F D+P+S +R IA+RL +KQ+IPHY LS+ VN+ + L +RK +N+ L
Sbjct: 380 APVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS 439
Query: 469 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
K+SVNDFIIKA A AC +VP NS WM++ IRQ VDVSVAV+TP GLITP + NA
Sbjct: 440 ---KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNA 496
Query: 649 DSRGI 663
+G+
Sbjct: 497 HIKGV 501
>UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 483
Score = 130 bits (313), Expect = 4e-29
Identities = 75/191 (39%), Positives = 108/191 (56%), Gaps = 8/191 (4%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV+ASP+AR+LAE K++ L +G+G G + D+
Sbjct: 185 RVFASPLARKLAEEKDLDLSQIRGSGPNGRIIKVDIENFKPVVAPKPSNEAAAKATTPAA 244
Query: 301 XXT-------FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLA 459
+ DLPLS MR+ IA RL +K PHY ++V+VN+EK + +R +N A
Sbjct: 245 SAADAAAPGDYEDLPLSNMRKIIASRLAESKNMNPHYYVTVSVNMEKIIRLRAALN---A 301
Query: 460 SEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXL 639
K+SVND +IKA AA ++VP VN+ WM FIRQ+ NVD+S+AVATP+GLITP +
Sbjct: 302 MADGRYKLSVNDLVIKATTAALRQVPEVNAAWMGDFIRQYKNVDISMAVATPSGLITPVI 361
Query: 640 HNADSRGIIDL 672
N + G+ ++
Sbjct: 362 RNTHALGLAEI 372
>UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;
Euplotes sp. BB-2004|Rep: Pyruvate dehydrogenase E2
subunit - Euplotes sp. BB-2004
Length = 459
Score = 127 bits (307), Expect = 2e-28
Identities = 75/181 (41%), Positives = 103/181 (56%), Gaps = 1/181 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV ASP AR+LA I + GTG G + + DL
Sbjct: 179 RVIASPFARKLASEGGIDISTIAGTGPGGRIVAADLDGASSAAQAFVSSAPASI------ 232
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+ D+P+S +R+ IAKRL+ +K++IPHY ++V +K L +R ++N S K
Sbjct: 233 --AYEDIPVSQVRKVIAKRLSESKETIPHYYVTVDAEADKLLKLRSMLNTHSES-----K 285
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+SVND IIKA + A K+VP NS W FIRQ+SNVDVSVAV+TPTGLITP + A+ +G
Sbjct: 286 ISVNDMIIKATSLASKKVPQTNSSWQGDFIRQYSNVDVSVAVSTPTGLITPIIKEANLKG 345
Query: 661 I 663
+
Sbjct: 346 L 346
>UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=10; Rickettsia|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rickettsia conorii
Length = 412
Score = 127 bits (307), Expect = 2e-28
Identities = 69/184 (37%), Positives = 111/184 (60%), Gaps = 1/184 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R++ASP+A+RLA+++NIR +G+G +G + D+
Sbjct: 130 RIFASPLAKRLAKMRNIRFESVKGSGPHGRIVKQDILSYTPSTAHNKIVSRNPEEYRL-- 187
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+P + +R+ IAKRL +KQ++PH+ LS+ NV+K L +R+ +N+ + +K+ +
Sbjct: 188 ------VPNNNIRKIIAKRLLESKQTVPHFYLSIECNVDKLLDIREDINKFFSEDKS-TR 240
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+SVNDFII AVA A + VP N+ W E IR ++NVD+SVAVA GL+TP + NA+ +
Sbjct: 241 ISVNDFIILAVAKALQEVPNANASWGEDAIRYYNNVDISVAVAIENGLVTPIVKNANQKN 300
Query: 661 IIDL 672
I++L
Sbjct: 301 ILEL 304
>UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=14; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 539
Score = 125 bits (302), Expect = 9e-28
Identities = 65/181 (35%), Positives = 99/181 (54%), Gaps = 1/181 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R++ASP+AR+LAE N+ L +GTG G + D+
Sbjct: 246 RIFASPLARKLAEDNNVPLSSIKGTGPEGRIVKADVEDFLASGSKETTAKPSKQVDSKVP 305
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+VD+P + +R+ A RL +KQ+IPHY L+V V+K + +R +N +
Sbjct: 306 ALDYVDIPHTQIRKVTASRLAFSKQTIPHYYLTVDTCVDKMMGLRSQLNS-FQEASGGKR 364
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+SVND +IKA A A ++VP NS W + +IRQF NV+++VAV T GL P + +AD +G
Sbjct: 365 ISVNDLVIKAAALALRKVPQCNSSWTDEYIRQFKNVNINVAVQTENGLYVPVVKDADKKG 424
Query: 661 I 663
+
Sbjct: 425 L 425
>UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Euglena
gracilis|Rep: Dihydrolipoyl transacetylase - Euglena
gracilis
Length = 434
Score = 124 bits (300), Expect = 1e-27
Identities = 63/121 (52%), Positives = 86/121 (71%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D P S MR++IA RLTA+K IPH+ L+V V VEK M +N A +K + K++V
Sbjct: 219 YEDTPASLMRKSIASRLTASKVEIPHFYLTVDVAVEKMKEMVAALNAG-AKDK-EYKITV 276
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
NDF++KA A ACK+VP NS W IR+F +VD+SVAVATPTGLITP ++NAD +G+ +
Sbjct: 277 NDFLVKACALACKKVPAANSQWHGDKIRRFHSVDISVAVATPTGLITPVVYNADLKGLKE 336
Query: 670 L 672
+
Sbjct: 337 I 337
>UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; Oryza
sativa|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 1812
Score = 124 bits (298), Expect = 3e-27
Identities = 66/182 (36%), Positives = 101/182 (55%), Gaps = 1/182 (0%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR+++SP+AR+LAE N+ L GTG G + D+
Sbjct: 1523 GRIFSSPLARKLAEDNNVPLSSVMGTGPDGRILKADIEDYLASVAKGGKREALAAPGL-- 1580
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
++ D+P + +R+ A RL ++KQ+IPHY L+V V+K + +R +N L
Sbjct: 1581 ---SYTDVPNTQIRKVTANRLLSSKQTIPHYYLTVDARVDKLIKLRGELNP-LQESSGGK 1636
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
K+S+ND +IKA A A ++VP NS WM FIRQ+ NV+++VAV T GL P + +AD +
Sbjct: 1637 KISINDLVIKAAALALRKVPQCNSSWMSDFIRQYHNVNINVAVQTEHGLFVPVIRDADKK 1696
Query: 658 GI 663
G+
Sbjct: 1697 GL 1698
>UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 484
Score = 121 bits (292), Expect = 1e-26
Identities = 58/123 (47%), Positives = 85/123 (69%), Gaps = 2/123 (1%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D +S MR I RL + Q+IP Y +S ++V K L +R+ +N A++ D K+S+
Sbjct: 250 YTDTEISNMRNIIGSRLLESTQTIPSYIVSSDISVTKLLRLRQSLNNDPANKNNDYKLSI 309
Query: 490 NDFIIKAVAAACKRVPTVNSHWM--ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
ND ++KA++ A KRVP VN+ W+ E+ IRQF NVDVSVAVATPTGLITP + N +S+G+
Sbjct: 310 NDILVKAISLAVKRVPEVNTCWLEKENVIRQFENVDVSVAVATPTGLITPIVKNVNSKGL 369
Query: 664 IDL 672
+ +
Sbjct: 370 VSI 372
>UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=40; Eukaryota|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Neurospora crassa
Length = 458
Score = 120 bits (289), Expect = 3e-26
Identities = 59/118 (50%), Positives = 80/118 (67%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D+P+SGMR+TIA RL + PH+ +S ++V K L +R+ +N +S K+SV
Sbjct: 227 YTDVPISGMRKTIAARLKESVTENPHFFVSTNLSVSKLLKLRQALN---SSADGRYKLSV 283
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
NDF+IKA+ A KRVPTVNS W + IRQF VDVSVAVATP GLITP + + +G+
Sbjct: 284 NDFLIKAMGIASKRVPTVNSSWRDGVIRQFETVDVSVAVATPNGLITPIVKGVEGKGL 341
>UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=6; Trypanosomatidae|Rep: Dihydrolipoamide
acetyltransferase, putative - Leishmania major
Length = 463
Score = 120 bits (288), Expect = 4e-26
Identities = 61/122 (50%), Positives = 82/122 (67%), Gaps = 1/122 (0%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQ-SIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
F D+P++ MR IAKRL +K IPHY L V+ LA+ K +N A + K++
Sbjct: 229 FTDIPVTTMRSVIAKRLHQSKNLEIPHYYLFDDCRVDNMLALIKQLN---AKGNGEYKIT 285
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
VND+I+KAVA A VP VNS W FIRQ++ VDVSVAVATPTGLITP + NA ++G++
Sbjct: 286 VNDYIVKAVARANTLVPEVNSSWQGDFIRQYATVDVSVAVATPTGLITPIIRNAQAKGLV 345
Query: 667 DL 672
++
Sbjct: 346 EI 347
>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_3,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 628
Score = 118 bits (284), Expect = 1e-25
Identities = 60/118 (50%), Positives = 82/118 (69%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+VD L+ MR TIA RL +K +IPHY L++TV ++K L +R+ +N+ VK+SV
Sbjct: 404 YVDTELTNMRLTIAARLLESKTTIPHYYLTMTVTMDKVLKVREELNKL-----QKVKISV 458
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
NDFIIKA A A K VP NS W ++IR+F+N D+S+AVAT GLITP + NA S+G+
Sbjct: 459 NDFIIKASALALKDVPQANSQWHGTYIRKFANADISIAVATDAGLITPIVFNAGSKGL 516
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 118 bits (283), Expect = 2e-25
Identities = 65/181 (35%), Positives = 100/181 (55%), Gaps = 1/181 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
+ +ASP+AR++A I L +GTG G + D+
Sbjct: 191 KFFASPLARKIALENGIPLAEIKGTGPNGRIVEADVKNYKPSAAAASTPAAGKSAAVPAD 250
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+ D+P S MR TI KRLT +KQ +PHY ++V VN+++ L +R++ N+ + ++ K
Sbjct: 251 ---YEDIPTSNMRRTIGKRLTESKQQLPHYYVTVEVNMDRVLKLREVFNK---AGESKTK 304
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+SVNDFI+KA + A VP NS W+ IR + D+ VAVATP GLITP + + ++G
Sbjct: 305 LSVNDFIVKAASLALADVPEANSAWLGETIRTYKKADICVAVATPNGLITPIIKDVGAKG 364
Query: 661 I 663
+
Sbjct: 365 L 365
>UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 421
Score = 116 bits (279), Expect = 5e-25
Identities = 67/184 (36%), Positives = 103/184 (55%), Gaps = 4/184 (2%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGD-LXXXXXXXXXXXXXXXXXXXXXXX 297
RV+ASP+ARRLAE + +RL G+G G + + D L
Sbjct: 126 RVFASPLARRLAEERGVRLETVSGSGPNGRVIAEDVLTARASSASEAVTHTVVAEHPLSK 185
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKA-- 471
F D+ +S ++ A+RLT +KQ +PH+ L+V V ++ + +R+ +N++LA +KA
Sbjct: 186 FFPDFEDVSVSAIKRVTAERLTESKQQLPHFYLTVDVRLDNMMGIRETLNKQLADDKAAE 245
Query: 472 DVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
K+SVNDFI+KA A A VP VN+ W+ IR++ D+SVAV T GL+ P + +A
Sbjct: 246 GAKISVNDFIVKASAKALLAVPDVNASWLGDKIRKYKKADISVAVQTERGLMVPIVRSAC 305
Query: 652 SRGI 663
G+
Sbjct: 306 CLGL 309
>UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=9;
Rickettsiales|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Wolbachia pipientis wMel
Length = 454
Score = 114 bits (274), Expect = 2e-24
Identities = 64/185 (34%), Positives = 108/185 (58%), Gaps = 1/185 (0%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR SP+A+++A+ + + + +GTG YG + D+
Sbjct: 172 GRTKISPLAKKIAQNEGVNVQQLKGTGPYGRIIKADVLEFLGSGIHTESPEKD------- 224
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
T V++ S MR+ IA+RLT +KQ++PH+ L+V V+K ++++ +N S +
Sbjct: 225 ---TIVEV--SNMRQVIAQRLTESKQNVPHFYLTVDCQVDKLISLKNEIN----SADENN 275
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
KV++ND IIKA A + K+ P +NS W+++ I ++SN+D+S+AVA GLITP + NAD +
Sbjct: 276 KVTINDLIIKAAAFSMKKFPDINSSWIDNKILRYSNIDISIAVALEDGLITPIVKNADKK 335
Query: 658 GIIDL 672
GI+ +
Sbjct: 336 GILSI 340
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 112 bits (269), Expect = 9e-24
Identities = 66/191 (34%), Positives = 101/191 (52%), Gaps = 8/191 (4%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGD-------LXXXXXXXXXXXXXXXXX 279
R+ ASP+ARR+A+ K + L +G+G +G + D L
Sbjct: 120 RIAASPLARRIAQAKGVGLDTLRGSGPHGRIVRIDVEAAISALPQTVDGAPAEAASISPP 179
Query: 280 XXXXXXXXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLA 459
+ ++PL+ +R+ IA+RLT AK +IPH+ L V +++ L R+ +N R
Sbjct: 180 ASRLHLIDTPYTEIPLTNIRKVIARRLTEAKATIPHFYLEVDCEIDELLKSRETLNAR-- 237
Query: 460 SEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXL 639
+S+ND +IKA A A ++VP N+ W + I QF +VD+SVAVAT GLITP +
Sbjct: 238 -SDGQYNLSLNDLVIKAAALALRQVPEANTAWTDDAIIQFQDVDISVAVATDGGLITPIV 296
Query: 640 HNADSRGIIDL 672
AD RG+ +
Sbjct: 297 RQADRRGLASI 307
>UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=3;
Saccharomycetales|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 482
Score = 112 bits (269), Expect = 9e-24
Identities = 54/121 (44%), Positives = 85/121 (70%), Gaps = 2/121 (1%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
++ D+P+S MR I +RL + Q IP Y +S +++ K L +R+ +N A++K K+S
Sbjct: 250 SYEDVPISTMRSIIGERLLQSTQGIPSYIVSSKISISKLLKLRQSLNAT-ANDK--YKLS 306
Query: 487 VNDFIIKAVAAACKRVPTVNSHWM--ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+ND ++KA+ A KRVP N++W+ E+ IR+F NVDVSVAVATPTGL+TP + N +++G
Sbjct: 307 INDLLVKAITVAAKRVPDANAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKG 366
Query: 661 I 663
+
Sbjct: 367 L 367
>UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 337
Score = 111 bits (267), Expect = 1e-23
Identities = 60/117 (51%), Positives = 78/117 (66%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
D+PLS +R TIAKRLTA+KQ IPH V V ++ LA+R+ + +K+ VS+ND
Sbjct: 102 DIPLSNIRATIAKRLTASKQQIPHEYQGVDVRIDDILALRQKL------KKSGTAVSLND 155
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
FIIKA A A + VPTVN W I +VD+SVAVATPTGLITP + N+D G++
Sbjct: 156 FIIKAAALALRSVPTVNVRWTPEGI-GLGSVDISVAVATPTGLITPIVENSDILGVL 211
>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase family protein; n=1;
Tetrahymena thermophila SB210|Rep: pyruvate
dehydrogenase complex dihydrolipoamide acetyltransferase
family protein - Tetrahymena thermophila SB210
Length = 646
Score = 110 bits (265), Expect = 3e-23
Identities = 53/115 (46%), Positives = 81/115 (70%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P++ MR+TIA+RL +K ++PH+ L++ V +++ L +RK +NE+ S K+SVND
Sbjct: 421 IPITPMRKTIAERLVQSKTTVPHFYLNIDVQMDEVLHLRKTLNEQSTS-----KISVNDL 475
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
I+KA A A + +P VNS W IRQF + DV+VAV+T TGLITP + NA++ G+
Sbjct: 476 IVKASALALRDMPGVNSQWHGDHIRQFKHADVAVAVSTKTGLITPIVFNAETLGL 530
>UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1;
gamma proteobacterium HTCC2207|Rep: Dihydrolipoamide
acetyltransferase - gamma proteobacterium HTCC2207
Length = 496
Score = 110 bits (265), Expect = 3e-23
Identities = 54/122 (44%), Positives = 81/122 (66%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
T P+SGMR+TIA RL A+KQ+ PH+++ + ++ LA+RK +N S D KVS
Sbjct: 271 TVASQPISGMRKTIAARLQASKQTAPHFRVHIDAEIDALLAVRKQIN----SSNTDAKVS 326
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
VNDFI+KA A+A +VP +N + + FSN D+SVAVA GLITP + +A+ +G++
Sbjct: 327 VNDFIVKACASALIKVPALNVQFDGEQLSYFSNADISVAVAIDDGLITPIVSDANHKGLV 386
Query: 667 DL 672
++
Sbjct: 387 EI 388
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 110 bits (264), Expect = 3e-23
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 2/179 (1%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLG--GQGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXX 294
GRV A+P+AR++A I I L G G+G G + DL
Sbjct: 126 GRVIATPLARKIASINGIDLSLIGSGSGPDGRIVKNDLLKLLDDAPQVQMHGHC------ 179
Query: 295 XXXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD 474
T +P+S MR IA+RL +KQ++PH+ LSVT ++ L+ +K + L +
Sbjct: 180 ----TETSIPISPMRRVIAQRLVESKQNVPHFYLSVTCYLQHLLSAKKKFYDCL-----E 230
Query: 475 VKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
KV+VNDF+IKA A A + P +N W FIRQ +D+SVAVA P GLITP + +AD
Sbjct: 231 TKVTVNDFVIKACAFALDKNPAMNVSWEGEFIRQNQTIDISVAVAIPDGLITPIVFSAD 289
>UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=2; Dictyostelium
discoideum|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Dictyostelium
discoideum (Slime mold)
Length = 592
Score = 109 bits (261), Expect = 8e-23
Identities = 53/118 (44%), Positives = 75/118 (63%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F D+P S +R+ A RLT +KQ+IPHY L++ V+K L +R +N VK+SV
Sbjct: 366 FTDIPHSNIRKVTAARLTESKQTIPHYYLTMECRVDKLLKLRSELNAMNT-----VKISV 420
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
NDFI+KA A + P VNS W + FIR++ N+D++VAV TP GL TP + D +G+
Sbjct: 421 NDFIVKASLPALRDNPVVNSTWTDQFIRRYHNIDINVAVNTPQGLFTPIVRGVDMKGL 478
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 107 bits (257), Expect = 2e-22
Identities = 68/192 (35%), Positives = 103/192 (53%), Gaps = 9/192 (4%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV ASP+A+++A + I LG GTG G + D+
Sbjct: 166 RVIASPLAKKMAGEQGIDLGDVSGTGPGGRIIKADIDNYEPTPAASPAPAPAASEEKTAK 225
Query: 301 XXT--------FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERL 456
F + LS +R+ IA+RLT +KQ++PHY L++ + ++ L +RK +N L
Sbjct: 226 PAPQAPEHGAPFEEEKLSNVRKVIARRLTESKQTVPHYYLTMDIVLDPLLKLRKELNASL 285
Query: 457 ASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPX 636
E VK+SVND +IKA+A A RVP N + +R++S D+SVAVA P+GLITP
Sbjct: 286 --EPDGVKLSVNDLLIKALARALIRVPQCNVSYHGDTMRKYSRADISVAVAAPSGLITPV 343
Query: 637 LHNADSRGIIDL 672
+ AD++G+ +
Sbjct: 344 ITEADTKGLAQI 355
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 107 bits (257), Expect = 2e-22
Identities = 52/117 (44%), Positives = 78/117 (66%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F D+ L+ + A+RLT AKQ++P + +SV V+K L +R +N ++AS K+S+
Sbjct: 255 FTDIELTNYKRVTAERLTEAKQTVPLFYVSVECEVDKLLTLRSQLN-KIAS----TKISI 309
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
ND +IKA + AC +VP NS WM F+R++ +VD+SVAV TP GLITP + A+ +G
Sbjct: 310 NDMLIKACSLACLKVPVTNSSWMGDFVRRYKDVDMSVAVQTPNGLITPIVPRANLKG 366
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 106 bits (254), Expect = 6e-22
Identities = 55/121 (45%), Positives = 80/121 (66%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F ++ L+GMR+ IAKRLT +K +IPHY V + + + +RK + +K ++KVSV
Sbjct: 262 FSEVDLTGMRKVIAKRLTESKTTIPHYYSMVDCELTEIVRLRKQL------KKDNIKVSV 315
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
NDFIIKA A A K+VP VN W S++D+SVAVAT GLITP + AD++G+++
Sbjct: 316 NDFIIKAAAMALKQVPEVNVTWNGQSATPLSSIDISVAVATDGGLITPIVKGADAKGLME 375
Query: 670 L 672
+
Sbjct: 376 I 376
>UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=31; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Zymomonas mobilis
Length = 440
Score = 105 bits (253), Expect = 7e-22
Identities = 67/185 (36%), Positives = 98/185 (52%), Gaps = 4/185 (2%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR+ ASP+A+RLA+ ++ L G+G +G + D+
Sbjct: 146 GRIKASPLAKRLAKKNHVDLKQVNGSGPHGRIIKADIEAFIAEANQASSNPSVSTPEASG 205
Query: 298 XXXTFV---DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEK 468
+ LS MR IA+RLT +KQ+IPH L+V V ++ L +R +NE LA +
Sbjct: 206 KITHDTPHNSIKLSNMRRVIARRLTESKQNIPHIYLTVDVQMDALLKLRSELNESLAVQ- 264
Query: 469 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
++K+SVND +IKA A A K P VN + + QFS D+SVAV+ GLITP L A
Sbjct: 265 -NIKISVNDMLIKAQALALKATPNVNVAFDGDQMLQFSQADISVAVSVEGGLITPILKQA 323
Query: 649 DSRGI 663
D++ +
Sbjct: 324 DTKSL 328
>UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=11;
Proteobacteria|Rep: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - Brucella
melitensis
Length = 421
Score = 104 bits (249), Expect = 2e-21
Identities = 49/115 (42%), Positives = 75/115 (65%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P + MR TIA+RL AK ++PH+ L+V ++ LA+R +NE+ + ++SVNDF
Sbjct: 199 VPHTSMRRTIARRLLEAKTTVPHFYLNVDCEIDALLALRSQINEK---REGSARISVNDF 255
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
+IKA AAA +RVP N W + + + +VD++VAVAT GLITP + +AD +
Sbjct: 256 VIKASAAALRRVPDANVIWTDEALLKLKDVDIAVAVATEGGLITPIIRSADQMSL 310
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 103 bits (246), Expect = 5e-21
Identities = 64/171 (37%), Positives = 93/171 (54%), Gaps = 1/171 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R+ ASP+ARRLA I L G+G +G + D+
Sbjct: 103 RLRASPLARRLAAEHGIDLTHLSGSGPHGRIVKIDIERALSAPPAAPVTAPAGSGD---- 158
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
F ++ S MR TIA+RL+ +K +IPH+ L+V +E+ LA+R +N + + K
Sbjct: 159 ---FTEIAHSNMRRTIARRLSESKSTIPHFYLTVECRMERLLALRAEINAPNNASRR--K 213
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITP 633
+S+ND I++AVA A + VP N W ES +RQ++ DV+VAVAT GLITP
Sbjct: 214 ISINDLIVRAVAVALREVPQANVGWTESAMRQYAQADVAVAVATDGGLITP 264
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 103 bits (246), Expect = 5e-21
Identities = 61/185 (32%), Positives = 97/185 (52%), Gaps = 3/185 (1%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGG-QGTGLYG--SLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
V+ASP+AR+ A + + G G+G G SLK
Sbjct: 182 VHASPIARKFANEVGLGMKGLTGSGRKGRVSLKDAQAAAIAGGLWTRPATVSRGPVATAA 241
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
+ P +GMR++IAK L +KQ++PH+ +V + V+ + +RK +N ++++ D
Sbjct: 242 PAGAGAEQPFTGMRKSIAKALVQSKQTVPHFYTTVDIEVDALMDLRKGMNG--SADEGDP 299
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
KVSVNDF++KA A A + P VN H ++ + F D+++AVA GLITP + N R
Sbjct: 300 KVSVNDFLLKACALALAKHPGVNVHVSDTGVTPFEQADIAMAVAIDGGLITPVVRNVGGR 359
Query: 658 GIIDL 672
G+ D+
Sbjct: 360 GLRDI 364
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 103 bits (246), Expect = 5e-21
Identities = 50/117 (42%), Positives = 76/117 (64%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P + MR+ IA RLT +K +IPH+ +S+ V+ +R N + +VK++VNDFI
Sbjct: 204 PHTAMRKVIASRLTESKTTIPHFYVSIDCEVDNLNLLRAEFNA-FYKDHENVKLTVNDFI 262
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IKAVA A + P +NS W+ +++ N+D+SVAV+T GL+TP + NAD +G+I L
Sbjct: 263 IKAVALAIHKHPEINSMWLSEGVKKNKNIDISVAVSTDDGLMTPIVFNADRKGLITL 319
>UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=6;
Anaplasmataceae|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 416
Score = 102 bits (245), Expect = 7e-21
Identities = 62/184 (33%), Positives = 99/184 (53%), Gaps = 1/184 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLG-GQGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV SP+A+++A + + +GTG YG + D+
Sbjct: 140 RVKVSPLAKKIASNLGVDVNLVKGTGPYGRIIKADILDVINQHGHIANSPEDA------- 192
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+F ++ S MR IA+RL +KQ+IPH+ +S+ V+ L +R +N +E D K
Sbjct: 193 --SFTEI--SSMRRVIAERLVYSKQTIPHFYVSIDCLVDSLLKLRLEIN----AENPDTK 244
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
V+VNDFIIKAVA + K+ P +N W + I F ++D+SVAV+ GLITP + AD +
Sbjct: 245 VTVNDFIIKAVAMSIKKFPEINVSWSDDKIVVFPSIDISVAVSIDNGLITPIIFGADKKS 304
Query: 661 IIDL 672
++++
Sbjct: 305 LLEI 308
>UniRef50_A1SQ65 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Nocardioides sp.
JS614|Rep: Catalytic domain of components of various
dehydrogenase complexes - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 427
Score = 102 bits (244), Expect = 9e-21
Identities = 67/187 (35%), Positives = 95/187 (50%), Gaps = 10/187 (5%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV+ASP+ARRLA + I + GTG G + D+
Sbjct: 132 RVFASPLARRLARLAEIPVEEIAGTGPRGRILRRDVEAAVAARPATPVVEQRAPASVVET 191
Query: 301 XXTF---------VDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNER 453
VD+P S +R +A RL +KQ+ PH+ L TV ++ + +R +NE
Sbjct: 192 PAPTQGSASKVEPVDVPHSRLRRAVANRLAESKQTAPHFYLRATVRADRLVDLRAELNEG 251
Query: 454 LASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITP 633
A+ +VS+ND ++KAVAAA RVP +N W +R FS+VDV+VAVAT GL+TP
Sbjct: 252 -----AETRVSLNDLVVKAVAAAHARVPEMNVVWTPDAVRSFSSVDVAVAVATDRGLVTP 306
Query: 634 XLHNADS 654
L + S
Sbjct: 307 VLRDVTS 313
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 101 bits (243), Expect = 1e-20
Identities = 56/121 (46%), Positives = 76/121 (62%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F ++P S +R+ IAKRLT +K SIPH + N+ L +RK LA K ++KVSV
Sbjct: 250 FSEIPASNIRKVIAKRLTESKSSIPHAYATTDCNLGAVLQLRK----ELA--KDNIKVSV 303
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
NDFIIKA AAA K++P VN W ++D+S+AVAT GLITP + A S+GI +
Sbjct: 304 NDFIIKATAAALKQMPNVNVTWNGEGATTLESIDISIAVATDRGLITPIIKQAASKGIQE 363
Query: 670 L 672
+
Sbjct: 364 I 364
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 101 bits (243), Expect = 1e-20
Identities = 49/119 (41%), Positives = 75/119 (63%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++P++ +R IA+RLT AKQ IPH+ L ++ E R +NE+LA VKVSVND
Sbjct: 207 EVPVTNIRRVIARRLTQAKQEIPHFYLRRRIDAEALREFRAQINEQLAP--TGVKVSVND 264
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
I+KAVA + P VNS W++ + + ++V +AVA TGL+ P LH+AD+ + ++
Sbjct: 265 LIVKAVATVLRDHPEVNSSWVDDKLLRHKRINVGIAVAVDTGLVVPVLHDADTLALSEV 323
>UniRef50_A4XEQ9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Sphingomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 480
Score = 99.5 bits (237), Expect = 6e-20
Identities = 61/182 (33%), Positives = 91/182 (50%), Gaps = 1/182 (0%)
Frame = +1
Query: 130 YASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXX 306
+ASP+ARR+A I L G +GTG G + D+
Sbjct: 198 FASPLARRIAAQHGIALAGIKGTGARGRISKADVMALVKPTTAAAPVFGAPFELVANQPQ 257
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
P +R+ +A+RLT AKQ+IPH+ L V+ +V+ + +RK N L + K S
Sbjct: 258 V---QPFDKVRKVVARRLTEAKQTIPHFYLRVSASVDALMDLRKTANLVLGT-----KAS 309
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
+ND+++KAVA A R P VN + F + DV++AVA+P GL+TP + AD I
Sbjct: 310 INDYLVKAVALALVRHPDVNVQVHGDSVHSFPHADVAIAVASPKGLVTPIVRQADRMHIA 369
Query: 667 DL 672
+
Sbjct: 370 QI 371
>UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding
protein; n=2; Ascaris suum|Rep: Dihydrolipoyl
dehydrogenase-binding protein - Ascaris suum (Pig
roundworm) (Ascaris lumbricoides)
Length = 368
Score = 99.5 bits (237), Expect = 6e-20
Identities = 52/118 (44%), Positives = 71/118 (60%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D+PL+ MR IA+RL +KQ IPH ++ + + KL R +K + VS+
Sbjct: 136 YTDIPLTNMRSVIARRLCESKQGIPHTYAIQKIDSDN---VNKL---RAKLKKEGISVSI 189
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
NDFIIKA A A + VP +N WM+ NVD+SVAVATP GLITP + AD+ G+
Sbjct: 190 NDFIIKACACALRAVPELNVKWMKDHAEALPNVDISVAVATPAGLITPIVFKADTLGV 247
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 98.3 bits (234), Expect = 1e-19
Identities = 59/186 (31%), Positives = 95/186 (51%), Gaps = 2/186 (1%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GRV ASP+AR +A + L +G+G G + D+
Sbjct: 156 GRVKASPLARAIAREAGLDLRTVRGSGPGGRVVRADVEAAVAAMRTAPAASPTAAPAAAA 215
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
++PL+ +R+ A+RLT + Q PH+ L+ T+N E + +R +N L+S D
Sbjct: 216 SQPDVEEIPLNTIRKITARRLTESMQQAPHFYLTRTLNAEPLIDVRARLNAALSSADPDT 275
Query: 478 -KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
K+S+ND I+K AAA ++ P VN + + Q ++ + VAVA P GLI P + +AD+
Sbjct: 276 AKISLNDLIVKVAAAALRKHPEVNVSYAGEKLLQHKHIHIGVAVAIPDGLIVPVIRDADT 335
Query: 655 RGIIDL 672
GI ++
Sbjct: 336 LGIREI 341
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 97.5 bits (232), Expect = 3e-19
Identities = 51/119 (42%), Positives = 75/119 (63%), Gaps = 6/119 (5%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLA---SEKADV---K 480
+P MR+TIA+RL AK +IPH+ L++ ++ LA+R +N +EK DV K
Sbjct: 223 VPHDNMRKTIARRLVEAKSTIPHFYLTLDCELDALLALRTQINAAAPMKKTEKGDVPAYK 282
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
+SVND +IKA+A A K VP N+ W E+ + + + DV VAV+ P GLITP + +AD +
Sbjct: 283 LSVNDMVIKAMAMALKAVPDANASWTETAMVKHKHADVGVAVSIPGGLITPIIRHADEK 341
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 96.7 bits (230), Expect = 5e-19
Identities = 66/184 (35%), Positives = 94/184 (51%), Gaps = 3/184 (1%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GRV ASP+AR++A + + L G+G G + D+
Sbjct: 245 GRVRASPLARKMASSQGLDLAAVHGSGPLGRVVKRDIEAALAQGPAAAKKAPEAAARPAA 304
Query: 298 XXXTFVD--LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKA 471
LP+S MR+ IA+R++ K +PH+ L TV+VE AM K+ E A E
Sbjct: 305 PGSRPAPKTLPISTMRKVIAQRMSEVKPGVPHFYL--TVDVEMDAAM-KIREEAKALES- 360
Query: 472 DVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
KVSVND ++KAVA A +R P +N + I QF+ DV +AVA GLITP + +AD
Sbjct: 361 --KVSVNDIVVKAVAVALRRSPKMNVSLQGNTILQFATADVGIAVAIEDGLITPIIKDAD 418
Query: 652 SRGI 663
+G+
Sbjct: 419 QKGL 422
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 95.1 bits (226), Expect = 1e-18
Identities = 50/122 (40%), Positives = 75/122 (61%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
TF ++P S +R IAKRLT +K ++PH + ++ L +R+ + K D+KVS
Sbjct: 274 TFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDL------VKDDIKVS 327
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
VNDFIIKA A K++P VN W +Q +D+SVAVAT GL+TP + +A ++GI
Sbjct: 328 VNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQ 387
Query: 667 DL 672
++
Sbjct: 388 EI 389
>UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Leptospira|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2 -
Leptospira interrogans
Length = 458
Score = 94.7 bits (225), Expect = 2e-18
Identities = 46/118 (38%), Positives = 72/118 (61%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
L ++GMR+TIA RL + +IPH+ L++ ++ +R N+ L E + K+S+ND
Sbjct: 233 LEITGMRKTIASRLAHSTSTIPHFYLTLELDATPLDTLRNSYNKDLKLEGSS-KISLNDL 291
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IIKA + + K VP VNS W E I + +D+ VAV+ GLITP + NAD + + ++
Sbjct: 292 IIKACSLSLKEVPEVNSSWREDHILEHGRIDIGVAVSIEGGLITPYIRNADQKSVSEI 349
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 94.7 bits (225), Expect = 2e-18
Identities = 57/179 (31%), Positives = 96/179 (53%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR+ SP+AR+LA K +G QG+G +G + D+
Sbjct: 261 GRIKISPLARKLANEKGYDIGQIQGSGDHGRIIKRDIENFTPAAQPAAQDSAVATAPVGT 320
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
++ ++ +S MR+TIAKRL ++K + PH+ +++ + ++ + RK +N + V
Sbjct: 321 E--SYEEINVSQMRKTIAKRLASSKFTAPHFYVTMEIRMDAIMKARKQINA-----VSPV 373
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
KVS ND IIKA A A ++ P +N++W+E IR +++ V +AVA GL P + AD+
Sbjct: 374 KVSFNDIIIKASALAIRKHPKINAYWLEDKIRYNNHIHVGMAVAVKDGLFVPVVRFADN 432
>UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Acetyltransferase -
Chlamydia trachomatis
Length = 429
Score = 94.3 bits (224), Expect = 2e-18
Identities = 61/182 (33%), Positives = 99/182 (54%), Gaps = 3/182 (1%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
V ASP+A++LA+ +N+ L G G+G G + DL
Sbjct: 146 VLASPLAKKLAKEQNLDLSGVTGSGPGGRIVKKDLEKAPPLRIAGFGYPEAPNVNPG--- 202
Query: 304 XTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKV 483
++++ PLS +RE I+KRL AAK IPH+ + + LA+ K + E+ ++K+
Sbjct: 203 -SYIEEPLSPVREVISKRLQAAKTFIPHFYVRQRIYASPLLALLKELQEQ------NIKL 255
Query: 484 SVNDFIIKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
S+ND I++A A A K P +NS + +++ I +FS +D+S+AVA P G+I P + AD +
Sbjct: 256 SINDCIVRACALALKEFPEINSGFNSVDNKIIRFSTIDISIAVAIPDGVIAPIVRCADRK 315
Query: 658 GI 663
I
Sbjct: 316 NI 317
>UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=11; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Psychroflexus torquis
ATCC 700755
Length = 572
Score = 94.3 bits (224), Expect = 2e-18
Identities = 66/199 (33%), Positives = 96/199 (48%), Gaps = 15/199 (7%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR+ ASP+A+++AE K I L G+G +G + D+
Sbjct: 271 GRILASPLAKKIAEDKGIDLRKVSGSGDHGRIVKKDVENFKPSVQPAEVKTEKVSIEEPK 330
Query: 298 XXXT--------------FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMR 435
+ F D+ S MR+TIAKRL +K S PHY L++ V++E +A R
Sbjct: 331 EQPSLPVAELYTPAGEESFEDVKNSQMRKTIAKRLLESKNSAPHYYLNIEVDMENAMASR 390
Query: 436 KLVNERLASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATP 615
+N E DVKVS ND +IKA A A ++ P VNS W + +++ V VAVA
Sbjct: 391 SHIN-----EMPDVKVSFNDLVIKASAMALRKHPQVNSSWDGEVTKIANHIHVGVAVAVD 445
Query: 616 TGLITPXLHNADSRGIIDL 672
GL+ P L AD + + +
Sbjct: 446 EGLLVPVLEFADQQSLTQI 464
>UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 549
Score = 93.5 bits (222), Expect = 4e-18
Identities = 54/120 (45%), Positives = 76/120 (63%), Gaps = 2/120 (1%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D+P S +R+ IAKRL +KQ+ PH LS V ++ LA R NE E+ VKVSV
Sbjct: 348 YEDIPNSQIRKVIAKRLLESKQTTPHLYLSQDVILDPLLAFR---NE--LKEQHGVKVSV 402
Query: 490 NDFIIKAVAAACKRVPTVNSHWM--ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
ND +IKAVA A + VP N++W + ++ +VD+S+AVAT GL+TP + NAD + I
Sbjct: 403 NDIVIKAVALALRNVPEANAYWNNDKEQAQKCVSVDISIAVATEKGLMTPIIRNADQKTI 462
>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Gammaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Acinetobacter sp. (strain ADP1)
Length = 513
Score = 93.1 bits (221), Expect = 6e-18
Identities = 62/183 (33%), Positives = 96/183 (52%), Gaps = 4/183 (2%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
+ A+P+ARRLA+ I L + +G G + D+
Sbjct: 224 IAATPVARRLAQTWGINLNDCRVSGTRGRVCKEDVEAVYYREHPVSETASTASCADTPVE 283
Query: 304 XTFVD-LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
V + ++ MR+ IA RL AK++ PH++LS+ VNVE A+R+ +N+ + +K
Sbjct: 284 LNSVKPIAMNAMRKAIASRLQLAKRNAPHFRLSIEVNVEALQALRQQINDTV----PQLK 339
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+S+ND +IKA AAA +VP VN + E I QF + D+SVAVA GLITP + A+
Sbjct: 340 LSINDMLIKAAAAALIKVPEVNVQYDEQKQQILQFKDADISVAVAIENGLITPIVKAANQ 399
Query: 655 RGI 663
+ +
Sbjct: 400 KSL 402
>UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=29; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rhizobium meliloti
(Sinorhizobium meliloti)
Length = 447
Score = 93.1 bits (221), Expect = 6e-18
Identities = 47/117 (40%), Positives = 72/117 (61%), Gaps = 2/117 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASE--KADVKVSVN 492
+P GMR+TIAKRL +KQ+IPH+ +SV ++ +A+R +N + K K+SVN
Sbjct: 220 VPHDGMRKTIAKRLVESKQTIPHFYVSVDCELDALMALRAQLNAAAPEKDGKPVYKLSVN 279
Query: 493 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
D +IKA+A A + VP N W + + + + DV VAV+ P GLITP + A+ + +
Sbjct: 280 DMVIKALALALRDVPDANVSWTDQNMVKHKHADVGVAVSIPGGLITPIVRQAELKSL 336
>UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Salinibacter ruber DSM 13855|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Salinibacter ruber
(strain DSM 13855)
Length = 465
Score = 92.7 bits (220), Expect = 7e-18
Identities = 49/118 (41%), Positives = 76/118 (64%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MRETIA+RL +K S PHY L+V ++VE+ + +R+ +N+ LA E+ K+S NDFI
Sbjct: 241 ITQMRETIARRLAESKYSAPHYYLTVDIDVERAIEVREDLND-LAEEQGRAKISFNDFIT 299
Query: 505 KAVAAACKRVPTVNSHWM--ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A + P VN+ + E I + + V + +AVA GLITP + +AD +G+ +L
Sbjct: 300 KACALSLHDHPYVNAAYRPDEGEIHKHNRVHIGIAVAIDEGLITPVIRDADRKGLSEL 357
>UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1164
- Rattus norvegicus (Rat)
Length = 539
Score = 92.3 bits (219), Expect = 1e-17
Identities = 49/122 (40%), Positives = 75/122 (61%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
TF ++P S +R+ IAKRLT +K ++PH + ++ L +R+ + K D+KVS
Sbjct: 261 TFTEIPASNIRKVIAKRLTESKSTVPHAYATANCDLGAVLKVRRDL------VKDDIKVS 314
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
VNDFII+A A K++P VN W + +VD+SVAVAT GLITP + +A ++ I
Sbjct: 315 VNDFIIRAAAVTLKQMPGVNVTWDGEGPKHLPSVDISVAVATDKGLITPIIKDAAAKDIR 374
Query: 667 DL 672
++
Sbjct: 375 EI 376
>UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative; n=2;
Chlamydiales|Rep: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative - Chlamydia
muridarum
Length = 428
Score = 91.9 bits (218), Expect = 1e-17
Identities = 60/183 (32%), Positives = 100/183 (54%), Gaps = 3/183 (1%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
+V ASP+A++LA+ +N+ L G G+G G + DL
Sbjct: 144 KVAASPLAKKLAKEQNLDLSGVAGSGPGGRIVKKDLEKAPPLRIAGFGYPEAPDVNPG-- 201
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
++V+ LS +RE+I+KRL AAK IPH+ + + LA+ K + + ++K
Sbjct: 202 --SYVEESLSPIRESISKRLQAAKTFIPHFYVRQRIYASPLLALLKELQVQ------NIK 253
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+S+ND I++A A A K P +NS + +++ I +FS +D+S+AVA P G+ITP + AD
Sbjct: 254 LSINDCIVRACALALKEFPEINSGFNSVDNTIIRFSTIDISIAVAIPDGVITPIIRCADR 313
Query: 655 RGI 663
+ +
Sbjct: 314 KNV 316
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 89.8 bits (213), Expect = 5e-17
Identities = 45/118 (38%), Positives = 74/118 (62%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F + P++ MR+ IAKRL+ + + PH+ L+++++++ +A R +NE A VK+S
Sbjct: 326 FTEKPVTQMRKVIAKRLSESLFTAPHFYLTMSIDMDGAIAARTKINEF-----APVKISF 380
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
ND ++KAVA A K+ P VNS W+ IR +V++ VAVA GL+ P + AD + +
Sbjct: 381 NDMVLKAVAIALKQHPAVNSSWLGDKIRYNEHVNIGVAVAVEDGLLVPVVRFADGKSL 438
>UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2
component, dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pyruvate
dehydrogenase complex , E2 component, dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 442
Score = 89.8 bits (213), Expect = 5e-17
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 2/184 (1%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGGQGTGLYGS-LKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
+ SP AR+LAE K I L G + D+
Sbjct: 155 IKVSPAARKLAEAKRINLAAVKPATTGDRIVLNDIETLPNGYGASEAQSGSGLVGYVNRA 214
Query: 304 X-TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+ D+P++ MR+ IA R+ A +P L+ + +++ + +R +N V+
Sbjct: 215 SESLTDIPMTQMRQAIANRMVQASAGVPVIYLTTKIEMDRLMDLRAQINSM-----EGVR 269
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+S+NDFI+KA + + P +N + I QF++VD+SVAV+ P GLITP + +ADS+G
Sbjct: 270 ISINDFIVKACGLSLAKFPAMNGAFQGDKIVQFNDVDISVAVSIPDGLITPIVRSADSKG 329
Query: 661 IIDL 672
+ +
Sbjct: 330 LASI 333
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4;
Magnoliophyta|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 637
Score = 89.4 bits (212), Expect = 7e-17
Identities = 53/120 (44%), Positives = 70/120 (58%), Gaps = 2/120 (1%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D P S +R+ IAKRL +KQ IPH L V ++ LA RK + E VKVSV
Sbjct: 407 YEDFPNSQIRKIIAKRLLESKQKIPHLYLQSDVVLDPLLAFRKEL-----QENHGVKVSV 461
Query: 490 NDFIIKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
ND +IKAVA A + V N+ W + I +VD+S+AVAT GL+TP + NAD + I
Sbjct: 462 NDIVIKAVAVALRNVRQANAFWDAEKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSI 521
>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E...; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E... - Apis mellifera
Length = 598
Score = 87.8 bits (208), Expect = 2e-16
Identities = 47/123 (38%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD-VKV 483
T+ D+P+S +R IAKRL +K +IPH ++ + ++K +NE KAD + +
Sbjct: 367 TYQDIPVSNIRSIIAKRLGESKITIPHSYATIDIKIDK-------INEIRKELKADGINI 419
Query: 484 SVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
S+NDFI KA A A P +N+ + I Q VD+S+AVA +GLITP + +A ++ I
Sbjct: 420 SINDFITKATAHALVECPFINTLYKNDQIIQMPRVDISIAVAIESGLITPIVFDATAKSI 479
Query: 664 IDL 672
+D+
Sbjct: 480 LDI 482
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 87.8 bits (208), Expect = 2e-16
Identities = 59/188 (31%), Positives = 91/188 (48%), Gaps = 4/188 (2%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GRV A+P+ARRLA + L G+G G +K+ D+
Sbjct: 118 GRVVATPLARRLAREAGLDLAQVSGSGPGGRIKAADVRQAPPALPVAPRDAASPAPAARA 177
Query: 298 XXXTFVD---LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEK 468
+ S + +++A+R+T AKQ +PH+ LS V LA+R +RL ++
Sbjct: 178 SLAPAAGEQRIEASALVQSMARRMTQAKQ-VPHFYLSAEAEVSALLALR----QRLNAQA 232
Query: 469 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
++++N F+I AVA A +P N W + I QF +DV VAV+T GL+ P LH
Sbjct: 233 DAPRLTLNHFVIAAVARALAAMPHQNRIWNDDHIVQFQGIDVGVAVSTERGLMAPVLHGL 292
Query: 649 DSRGIIDL 672
D + D+
Sbjct: 293 DHASLDDI 300
>UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, component
X; n=2; Dictyostelium discoideum|Rep: Pyruvate
dehydrogenase complex, component X - Dictyostelium
discoideum AX4
Length = 413
Score = 87.4 bits (207), Expect = 3e-16
Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 2/121 (1%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ D+P + +R IA +L+ +KQ +PH+ ++V ++ LAMRK + E +VK+SV
Sbjct: 129 YEDIPNNNIRRVIATKLSQSKQQVPHFYMTVECELDNVLAMRKSMPE-------NVKISV 181
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSN--VDVSVAVATPTGLITPXLHNADSRGI 663
NDF+++A A A + P NS W + N VD+S AV+T GLITP + N D + +
Sbjct: 182 NDFVLRACALALRDNPQANSKWSDEHGEAILNPTVDISFAVSTDRGLITPIITNTDKKQL 241
Query: 664 I 666
+
Sbjct: 242 L 242
>UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Plesiocystis pacifica SIR-1|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Plesiocystis pacifica
SIR-1
Length = 436
Score = 83.4 bits (197), Expect = 5e-15
Identities = 60/189 (31%), Positives = 90/189 (47%), Gaps = 9/189 (4%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R+ ASP+ARRLA ++ L GTG +G + D+
Sbjct: 136 RIPASPVARRLAREHDLELAAITGTGPHGRVVKADVEKAIAEGTGKAAAAPAAGEFSGEV 195
Query: 301 XX---TFVDLP-----LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERL 456
+V P LS MR+ IA+ +T AKQ PHY L++ V++EK A R NE +
Sbjct: 196 DGWGRPYVSRPDDSVRLSMMRKAIARNMTKAKQETPHYYLTMDVDMEKAFAFRADFNEAV 255
Query: 457 ASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPX 636
K+S ND I+KAVA + + P+VN+ + +V+V +AVA GL+ P
Sbjct: 256 PE---GTKISFNDLIVKAVARSLRDFPSVNASFDGDKAIIRGDVNVGIAVAVEDGLVVPV 312
Query: 637 LHNADSRGI 663
+ AD + +
Sbjct: 313 VRYADQKSL 321
>UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 288
Score = 80.6 bits (190), Expect = 3e-14
Identities = 47/121 (38%), Positives = 70/121 (57%), Gaps = 2/121 (1%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
D + MR TIA RLT +K PH S V++ + A+R+ V + + VKVSVND
Sbjct: 79 DAATTKMRRTIASRLTESKTRTPHAYASADVDLSEVAALRRRV-----MDASGVKVSVND 133
Query: 496 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
++ AV A + VP +N+ W ++ R + +VDV VAVAT GLITP + AD + + +
Sbjct: 134 CVMYAVGRALREVPELNAGWDDATGGRRAYESVDVCVAVATDDGLITPIVTRADEKTLTE 193
Query: 670 L 672
+
Sbjct: 194 I 194
>UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 396
Score = 80.6 bits (190), Expect = 3e-14
Identities = 42/114 (36%), Positives = 64/114 (56%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
TF D+P + MR IAKRL +K +IPH S ++ L ++ + ER + VS
Sbjct: 176 TFTDVPNTEMRREIAKRLLKSKTTIPHVYASTDCVMDNLLQLKSHLKER------GLTVS 229
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
VND ++K A ++VP +N+ W I ++D++V VAT G+ITP + NA
Sbjct: 230 VNDLLVKVAAVCLRKVPEMNAVWNGKEIEYLKDIDLAVDVATDVGIITPVIRNA 283
>UniRef50_UPI0000E4A223 Cluster: PREDICTED: similar to
dihydrolipoamide S-acetyltransferase precursor, partial;
n=4; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to dihydrolipoamide S-acetyltransferase
precursor, partial - Strongylocentrotus purpuratus
Length = 232
Score = 80.2 bits (189), Expect = 4e-14
Identities = 49/152 (32%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GRV+ASP+AR+LA + I + QGTG G + D+
Sbjct: 91 GRVFASPLARKLAAERGININTLQGTGPAGRIVKADIESYVPGVAGVPMPAAVPGAG--- 147
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
F D+P+ +R A +KQ+IPHY L ++V L ++ +NE + SE D
Sbjct: 148 ----FTDIPVDALRMEQANAAVYSKQTIPHYYLMADIDVGSVLRLQGSLNE-MVSE--DT 200
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIR 573
+++N+F+IKA A +C+++P NS W IR
Sbjct: 201 PITLNEFVIKAAALSCQKIPDANSAWFGDKIR 232
>UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2
component; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Dihydrolipoamide
acyltransferase E2 component - Candidatus Sulcia
muelleri str. Hc (Homalodisca coagulata)
Length = 371
Score = 80.2 bits (189), Expect = 4e-14
Identities = 53/181 (29%), Positives = 88/181 (48%), Gaps = 1/181 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R+ SP+A++LA K I L +GTG+ G + D+
Sbjct: 98 RILISPLAKKLAFDKGISLDNIKGTGINGRIIKKDIERYIDNNLDKTISSN--------- 148
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
++ S +R+ I+KRL +K PHY L + V ++ + +R +NE+ +K
Sbjct: 149 -----EVNHSNIRKIISKRLINSKIESPHYSLFIEVIMDNLIKLRDSINEKKYLDK---- 199
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+S ND I+KA A A K P +NS W E I +N+++ +AVA GLI P ++ + +
Sbjct: 200 ISFNDLIVKASALAIKENPKINSSWTEKSILYHNNINIGIAVALEDGLIVPVINQVNEKS 259
Query: 661 I 663
+
Sbjct: 260 L 260
>UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Chlamydomonas reinhardtii|Rep: Dihydrolipoamide
S-acetyltransferase - Chlamydomonas reinhardtii
Length = 643
Score = 79.8 bits (188), Expect = 6e-14
Identities = 46/122 (37%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
++ D P S +R IA RL +K++ P + ++ +R + R KVS
Sbjct: 414 SYTDTPNSQIRRIIAARLLDSKRNTPSLYMRADACLDAVADLRASLAAR------GTKVS 467
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
VND +++AVA A + VP N HW E+ +R F VD+SVAVAT GLITP + AD +G
Sbjct: 468 VNDCVLRAVALALRDVPAANVHWDEAAGDVRAFGGVDISVAVATERGLITPIVRAADVKG 527
Query: 661 II 666
++
Sbjct: 528 LL 529
>UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase (E2)
component, and related enzyme; n=1; marine gamma
proteobacterium HTCC2080|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzyme - marine gamma
proteobacterium HTCC2080
Length = 388
Score = 78.2 bits (184), Expect = 2e-13
Identities = 43/113 (38%), Positives = 65/113 (57%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PLS R+TIA+RLT AKQ+IPH+ LS ++ +A R+ +N D KVSVND
Sbjct: 173 IPLSPTRKTIARRLTEAKQTIPHFYLSADYALDGLMAHRQTLN-----GSGDTKVSVNDL 227
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
++ V A R P VN + + I QF +++VA+AT GL + +++
Sbjct: 228 LVWCVGQALMREPRVNVNLVGDDIHQFEAANIAVAIATDDGLYPATIPGVEAK 280
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 77.8 bits (183), Expect = 2e-13
Identities = 39/116 (33%), Positives = 65/116 (56%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++P++G+R+ IAK ++ +KQ IPH + V V+ + R V + E+ ++
Sbjct: 188 EIPINGVRKAIAKHMSVSKQEIPHAWMMVEVDATGLVRYRNTVKDSFKKEEG-YSLTYFA 246
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
F IKAVA A K P +NS W I + +N+++S+A+A L P + NAD + I
Sbjct: 247 FFIKAVAQALKEFPQLNSTWAGDKIIEHANINISIAIAAGDLLYVPVIKNADEKSI 302
>UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04873 protein - Schistosoma
japonicum (Blood fluke)
Length = 304
Score = 77.0 bits (181), Expect = 4e-13
Identities = 49/124 (39%), Positives = 72/124 (58%), Gaps = 3/124 (2%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F D+ LS MR+ IA+RL+ K IPH + T +++ +RK + L + S+
Sbjct: 38 FTDVALSNMRKVIAQRLSELKLCIPHGYVRATTCIDRLNNLRKELKVNLG-----MNFSI 92
Query: 490 NDFIIKAVAAACKRVPTVNSHW---MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
NDFIIKA A A + P NS + ES + +VD+S+AVAT +GLITP L +AD+
Sbjct: 93 NDFIIKACALALRLFPDFNSIYDAQAESPV-YLRSVDISMAVATSSGLITPILKSADTLT 151
Query: 661 IIDL 672
+ D+
Sbjct: 152 VSDI 155
>UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 414
Score = 74.9 bits (176), Expect = 2e-12
Identities = 35/118 (29%), Positives = 70/118 (59%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P +GMR+ IA+++ + + PH+ +++ V + + L +R+ +N +L ++A K+S+N
Sbjct: 191 IPFTGMRKIIAEKMQKSINTAPHFYVTMEVKMREILKLRETLNSKLKEDEA--KISLNTL 248
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
++KA A K P NS+ E I + +++ +AVA GLI P + D +G+ ++
Sbjct: 249 LMKAAGIAIKDYPIFNSYVEEGQIILRNEINIGLAVALDEGLIVPVIREVDKKGLKEI 306
>UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2)
component of 2-oxoacid dehydrogenase complexes; n=1;
Burkholderia xenovorans LB400|Rep: Dihydrolipoamide
acyltransferase (E2) component of 2-oxoacid
dehydrogenase complexes - Burkholderia xenovorans
(strain LB400)
Length = 428
Score = 74.9 bits (176), Expect = 2e-12
Identities = 52/183 (28%), Positives = 83/183 (45%), Gaps = 3/183 (1%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGD--LXXXXXXXXXXXXXXXXXXXXXX 294
R ++P+ARRLA + I L G+G G +++ D L
Sbjct: 137 RGISTPLARRLARERGIDLTNLAGSGPRGRIRARDVELAPANSPASAPDVPLPATASRAA 196
Query: 295 XXXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD 474
+ + +TIA+RL +KQ+IPH+ LSV + +R +N+ ++ +
Sbjct: 197 QVAQAATVRAATSIEKTIARRLVTSKQTIPHFYLSVEAEISAVQRLRSQLNDAQSNRR-- 254
Query: 475 VKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+VN F++ AV A VP N W +S I F+ DV VAV T GL+ P L +
Sbjct: 255 --FTVNHFVVAAVGRALALVPEANRVWDDSGITSFAATDVGVAVHTERGLLVPVLRDVGR 312
Query: 655 RGI 663
+ +
Sbjct: 313 QAL 315
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 74.9 bits (176), Expect = 2e-12
Identities = 38/115 (33%), Positives = 66/115 (57%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PLS MR+TI++R+ + Q PH +S+ V++ LA+R N A + ++SVND
Sbjct: 234 VPLSNMRKTISRRMIQSWQQFPHIFVSIEVDMGAALALRAQAN---AGRPREDQISVNDM 290
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
++KA A A P +N+ + + I V++++AVA +GL+ P + N R +
Sbjct: 291 VVKACAVALLAFPNLNASYSDDGIILHPTVNIAIAVALESGLMAPVVANCQDRSL 345
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 74.5 bits (175), Expect = 2e-12
Identities = 40/119 (33%), Positives = 72/119 (60%), Gaps = 5/119 (4%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PLS MR+ IA+ + +K +PH L++ V+V+ +A+R E++A+ + +VSVND +
Sbjct: 212 PLSRMRKAIARAMNESKPGVPHIYLTIEVDVDALMALR----EQIAA--SGTRVSVNDLV 265
Query: 502 IKAVAAACKRVPTVNSHWMESF-----IRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
+KA A A +VP +N + ++ I + S +++ VAVA GL+ P + +AD + +
Sbjct: 266 VKAAAKALAKVPAINVSFSQTADGQPGIVRHSQINIGVAVALDDGLVAPVVRDADKKSV 324
>UniRef50_A0JS87 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Arthrobacter sp. FB24|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 477
Score = 73.7 bits (173), Expect = 4e-12
Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 12/192 (6%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV +SP ARRLA+ + +GG GTG G++ D+
Sbjct: 180 RVRSSPRARRLADQLGVDIGGVPGTGPDGAVTEADVQRAVSGHTAAAPAEEALPEEATVP 239
Query: 301 XXTFV---DLP-------LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNE 450
+ + P LS +R I +T +K+SIPHY +S T+++ +A + VNE
Sbjct: 240 GAEALPPKEAPPSEAQDRLSSLRRAIGSLMTRSKKSIPHYYVSTTLDLRAAIAWMQQVNE 299
Query: 451 RLASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVA-TPTGLI 627
+ ++ + ++KA A A K VP VN + + R S+V + VAVA GL+
Sbjct: 300 Q---RPVASRLVPSALLLKATALAAKEVPEVNGFFTDGVFRPSSSVHLGVAVALRHGGLV 356
Query: 628 TPXLHNADSRGI 663
P +H+AD+ +
Sbjct: 357 APAIHDADTLAV 368
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 72.5 bits (170), Expect = 8e-12
Identities = 47/181 (25%), Positives = 89/181 (49%), Gaps = 1/181 (0%)
Frame = +1
Query: 133 ASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXXT 309
A+P+A+++AE+K + L QG+G YG + D+
Sbjct: 164 ATPLAKKVAEVKGVALEKVQGSGPYGKVYREDVEHAQAASPVEDKGNR------------ 211
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ LSG+R+ +AKR+ + S PH ++ +++ T+ +R + + E ++S
Sbjct: 212 ---VKLSGLRKVVAKRMVDSAFSAPHVTITTEIDMSSTIKIRSQLLGMIEQETG-YRLSY 267
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
+ ++KAVA A PT+N+ + E+ I +V + +AVA GL+ P + + D +G+
Sbjct: 268 TEIVMKAVAHALMSHPTINASFFENEIVYHEDVHIGLAVAVEGGLVVPVVKHVDKKGLAQ 327
Query: 670 L 672
L
Sbjct: 328 L 328
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 72.5 bits (170), Expect = 8e-12
Identities = 45/181 (24%), Positives = 82/181 (45%), Gaps = 1/181 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R++ +P+AR+LA+ N+ + +GTG G + D+
Sbjct: 118 RIFITPLARKLAKEHNVNIEEVEGTGGNGRITKRDILREASNQISTQAVKQAANENAQVA 177
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+ LS +R+TIA+ + A+ + L + LA R+L+ S + +K
Sbjct: 178 HSDDIGEGLSPIRKTIARNMRASLHNTAQLTLHRKAHANALLAFRRLLKTESESHQLQLK 237
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+SV I +A A ++V +NS + +++F NV + +A + GL+ P + NAD
Sbjct: 238 LSVTVLIARATILALQQVGAMNSRYENGQLKEFENVHLGIATSLDDGLVVPVIRNADHLS 297
Query: 661 I 663
I
Sbjct: 298 I 298
>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=37; Bacillales|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Bacillus subtilis
Length = 424
Score = 72.1 bits (169), Expect = 1e-11
Identities = 37/116 (31%), Positives = 62/116 (53%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++P++G+R+ IA + +K IPH + V+V +A R + + + ++
Sbjct: 196 EIPVTGVRKAIASNMKRSKTEIPHAWTMMEVDVTNMVAYRNSIKDSFKKTEG-FNLTFFA 254
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
F +KAVA A K P +NS W I Q ++++S+AVAT L P + NAD + I
Sbjct: 255 FFVKAVAQALKEFPQMNSMWAGDKIIQKKDINISIAVATEDSLFVPVIKNADEKTI 310
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 70.9 bits (166), Expect = 3e-11
Identities = 36/116 (31%), Positives = 67/116 (57%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+ IA+RL +K + VN++ + +RK E +K +V++ F +
Sbjct: 196 MTRLRQRIAERLLDSKNNTAMLTTFHEVNMKPIILLRKKYGEDF-EKKHNVRIGFMSFFV 254
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAV A K P +N++ ++ I + N D+S+A++TP GLITP + NAD+ + ++
Sbjct: 255 KAVIQALKNFPEINAYIDQTDIVFYKNFDISIAISTPRGLITPVIRNADTMTMAEI 310
>UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 585
Score = 70.5 bits (165), Expect = 3e-11
Identities = 41/126 (32%), Positives = 76/126 (60%), Gaps = 8/126 (6%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLAS--EKADVKVSVN 492
+P++G+R T+A+ + A+ S PH ++V+V +T+A R ER+A+ + A ++V+
Sbjct: 354 IPVTGVRRTMARAMVASVFSAPHATEFLSVDVTETMAAR----ERIAALPDFAGIRVTPL 409
Query: 493 DFIIKAVAAACKRVPTVNSHWM------ESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+ KA+ A +R P +NS W+ + I+ +++ +AVA P GL+ P + +A S
Sbjct: 410 LLVAKALLTAVRRHPMINSTWVGDTSGENAEIQVHERINLGIAVAGPRGLVVPNIPDAGS 469
Query: 655 RGIIDL 672
RG++DL
Sbjct: 470 RGLVDL 475
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 69.7 bits (163), Expect = 6e-11
Identities = 47/180 (26%), Positives = 81/180 (45%), Gaps = 1/180 (0%)
Frame = +1
Query: 136 SPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXXTF 312
SP RRL ++ +GTG+ G + D+ +
Sbjct: 114 SPAVRRLLAEHSLEASQVKGTGVGGRITREDIEAHLAAAKQAPAVAEAPAAVAPVAARSE 173
Query: 313 VDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVN 492
+P++ +R+T+A RL AK S VN++ + +RK ++ + +++
Sbjct: 174 KRVPMTRLRKTVANRLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGDQFEARHG-IRLGFM 232
Query: 493 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
F +KAV A KR P +N+ I + D+S+AV+TP GL+TP L + D+ G D+
Sbjct: 233 SFYVKAVTEALKRYPEINASIDGDDIVYHNYFDISMAVSTPRGLVTPVLKDCDTLGFADV 292
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 69.7 bits (163), Expect = 6e-11
Identities = 37/115 (32%), Positives = 65/115 (56%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ + PLS +R+T AKR+ ++Q +P + ++ T+ ++ A+ + E K+SV
Sbjct: 219 YTEEPLSRLRQTAAKRMVESQQQVPPFFVTSTIEMDAIQALLPKLREAHGG-----KLSV 273
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+ ++KA A A K+ P +NS + + +V +SVAVAT GL+ P + N DS
Sbjct: 274 TELLLKACAIALKKFPALNSTFAGDKLLVHKDVHISVAVATDAGLLAPVVRNCDS 328
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 69.3 bits (162), Expect = 8e-11
Identities = 38/118 (32%), Positives = 65/118 (55%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P++ +R+ +A+RL AK S VN++ + +RK E ++ +++ F
Sbjct: 179 VPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAF-EKRHGIRLGFMSF 237
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KAV A KR P VN+ + + DVS+AV+TP GL+TP L + D+ G+ D+
Sbjct: 238 YVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADI 295
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 68.5 bits (160), Expect = 1e-10
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV-KVSVNDF 498
PL G+R+ +AKR+ + S L+ T N LAMRK V A E + K+++ND
Sbjct: 223 PLKGVRKVVAKRMMESLTSTAQLTLNTTANAAGILAMRKKVKN--ADEALGLNKITLNDL 280
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
+ AV+ + P N+H + + +F V + A TP GL+ P + +A + G+
Sbjct: 281 VCFAVSRTLLKYPVFNAHLEDGVLTEFEQVHLGFACDTPRGLLVPVIRSAQALGL 335
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 67.7 bits (158), Expect = 2e-10
Identities = 37/117 (31%), Positives = 59/117 (50%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PLS +R+T+A+RL AA+Q ++ + + +R ER E+ +K+ + F
Sbjct: 172 PLSPLRQTVARRLLAARQQTAMATTINEADLSRIMELRSQYGERFM-ERNGIKLGLMSFF 230
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA A + P +N+ E I D+ +AVAT GL+ P L NAD D+
Sbjct: 231 VKACVEALREFPVINARLEEEAIVYQHFYDIGIAVATDQGLVAPVLLNADRLNFADI 287
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 67.7 bits (158), Expect = 2e-10
Identities = 36/120 (30%), Positives = 70/120 (58%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R+ IA+++ +K + PH+ V+ + +A+R +N +LA+ ++K++ F
Sbjct: 186 VPLRGLRKKIAEKMVRSKFTAPHFAFVEEVDATELVALRARLNAQLAAAGENIKLNYLPF 245
Query: 499 IIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IIKA AA K+ P +N+++ E+ + ++ +A ATP GL + +AD + +L
Sbjct: 246 IIKATVAALKKFPHLNANFDEASQELVVRGEFNIGMAAATPDGLTVAVVKSADRLTLAEL 305
>UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2
component, putative; n=2; Streptococcus|Rep:
Dihydrolipoamide acetyl transferase, E2 component,
putative - Streptococcus sanguinis (strain SK36)
Length = 419
Score = 67.3 bits (157), Expect = 3e-10
Identities = 43/185 (23%), Positives = 85/185 (45%), Gaps = 1/185 (0%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR++ +P+AR++A+ K + GTG G + D+
Sbjct: 127 GRIFITPLARKIAKEKGYDISLISGTGGNGRITRRDVENYKPEALPNQTPESSSAVLQHA 186
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
+ L GMR+TIA+R+ + Q+ L V++ + +A R+ + ++ S +
Sbjct: 187 GQVDY-GAGLMGMRKTIAERMMNSLQASAQVTLHRKVDISRLIAFRQDMKGKVTSPLENG 245
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
++S+ + KAVA A K P +N+ + ++ ++ + +A A GL+ P + + D
Sbjct: 246 EISITTLLTKAVAKALKDHPQLNAWYFNGQYQEVEDIHIGIATALSDGLVVPVIRHVDKL 305
Query: 658 GIIDL 672
+ DL
Sbjct: 306 TLADL 310
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 66.9 bits (156), Expect = 4e-10
Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 4/122 (3%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G+R A + + +IPH VT++V T +M L R E A +K+S
Sbjct: 318 IPVRGVRRETAAAMVRSAFTIPHVTEFVTIDV--TPSMETLDRLRNRPEFAGIKLSPLTL 375
Query: 499 IIKAVAAACKRVPTVNSHW----MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
KAV A +R P VNS+W E +R + V++ +A ATP GL+ P + +AD +I
Sbjct: 376 TAKAVLLALRRYPLVNSYWDDASDEIVVRHY--VNLGIATATPRGLVVPNIKDADRLSLI 433
Query: 667 DL 672
DL
Sbjct: 434 DL 435
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 66.5 bits (155), Expect = 6e-10
Identities = 40/116 (34%), Positives = 62/116 (53%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+ G+R+ IA + + S PH +SV V+V+ T M + + A + VKVS +
Sbjct: 231 VKGVRKAIANAMVTSAFSAPH--VSVFVDVDATRTMEFVKRLKSAPDFVGVKVSPLLIMA 288
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA+ A +R PTVNS W + I V++ +A ATP GLI P + A +++L
Sbjct: 289 KAIVWAVRRNPTVNSTWTDEEIIVRHYVNLGIAAATPRGLIVPNVKEAQGMSLLEL 344
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 66.1 bits (154), Expect = 7e-10
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 4/186 (2%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
+ A+P+A+RLA+ NI L GTG G + D+
Sbjct: 94 IKATPVAKRLAKENNIDLSLITGTGPGGRITEEDVKKFISEQKVKTEEEGPKKEVAVIEG 153
Query: 304 XTFVD---LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD 474
+P+ +R+TI++R+ + IPH + V+V + + +R+ +N +D
Sbjct: 154 QALEKVERMPMDNIRKTISQRMKKSWSEIPHVTEDIKVDVTELVNLRENLNHI-----SD 208
Query: 475 VKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
K + D I KA A K+ P VN +I + S++++ +AVA GLI P + AD
Sbjct: 209 NKFTYTDLIAKACVIAIKKNPVVNWSIEGEYIIKNSSINLGIAVALDNGLIVPVVKEADK 268
Query: 655 RGIIDL 672
+ +++L
Sbjct: 269 KSLLEL 274
>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 435
Score = 66.1 bits (154), Expect = 7e-10
Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P GMR IA+ + + HY ++V K + +RK + A + V +S F
Sbjct: 206 IPFRGMRRRIAEGMVKSYTEAVHYTYVEQIDVTKLVTLRKQAKKAAAEQ--GVSLSYLPF 263
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQF--SNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IIKAV A KR P VN+ E+ R + VA AT GL+ P +H+AD ++DL
Sbjct: 264 IIKAVCHALKRFPIVNAELDEAQKRIVLKKRYSIGVAAATDQGLMVPVIHDADMLSLLDL 323
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 66.1 bits (154), Expect = 7e-10
Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 3/185 (1%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
V A P ARRLA+ I L +GTG G + D+
Sbjct: 95 VAAMPAARRLAKELGIDLSKVKGTGPGGVITVEDVKRYAEETAKATAPAPAPKAVEKAEE 154
Query: 304 XTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKV 483
V P+ G+R +A++++ AK+ IPH V+ + + +R+ V + +EK +++
Sbjct: 155 AEVV--PVRGIRRAVAEKMSKAKRLIPHAYHLEEVDFTELIKLRERV--KAEAEKRGIRL 210
Query: 484 SVNDFIIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
++ FI KAVA A + P +NS + E + I V++ + V T GL+ + NAD +
Sbjct: 211 TLLPFIAKAVAMALREYPMLNSEYDEEKNAIVVKKEVNLGIGVDTEQGLVVVVVKNADKK 270
Query: 658 GIIDL 672
G++++
Sbjct: 271 GLLEM 275
>UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=2; Mycoplasma|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
pneumoniae
Length = 402
Score = 66.1 bits (154), Expect = 7e-10
Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+ ++ MR+ IA+ + + ++IP L+ VN K R+ VN LA K ++K+S F
Sbjct: 175 IAITTMRKAIAEAMVKSHENIPATILTFYVNATKLKQYRESVNG-LALSKYNMKISFFAF 233
Query: 499 IIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA+ A K+ P N + + + I +V+V +AV TP GLI P + A ++ ++D+
Sbjct: 234 FVKAIVNALKKFPVFNGRYDKERNLIVLNKDVNVGIAVDTPDGLIVPNIKQAQTKSVVDI 293
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 66.1 bits (154), Expect = 7e-10
Identities = 35/116 (30%), Positives = 64/116 (55%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+ I++RL + K + VN++ L +R+ E L +K +K+ + F +
Sbjct: 186 MTRLRKKISERLLSTKNNTASLTTFNEVNMQSILNLRRKYGE-LFKQKHGIKLGLMSFYV 244
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAV A K P +N+ I ++ D+S+A++TP GL+TP L NAD + ++
Sbjct: 245 KAVIEALKIFPEINASIDNDEIIYYNYFDISIAISTPRGLVTPVLKNADLMSMAEI 300
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/114 (29%), Positives = 63/114 (55%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PL+ MR IA + + + P V++ + LA R+ R + E+ ++++V +I
Sbjct: 210 PLTTMRRVIADHMVRSLRDAPQATTVFEVDMGRVLAHRE--RYRSSFEQQGIRLTVTAYI 267
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
++AVA A +RVP +N+ + + I + + + +AVA GLI P L +AD + +
Sbjct: 268 VQAVATALRRVPALNTRFTDDGIITYRRIHIGIAVALDDGLIVPVLRDADEKSL 321
>UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC
14580|Rep: AcoC - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 377
Score = 65.3 bits (152), Expect = 1e-09
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 1/184 (0%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R+ SP AR++A+ NI + +GTG G + D+
Sbjct: 97 RIKISPAARKIAQSANIDIKTLKGTGPGGRITKADVLQALPGRPNKQAAKAEAEERP--- 153
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
P S MR+TIA R+T + Q+ +++ ++ K ++K +NE A + D K
Sbjct: 154 -------PASPMRKTIAARMTESLQNSAQLTITMKADITKLTVLQKQLNE-TAQSRYDTK 205
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+++ DF +A + P +NS + + + F +V + VA A GL P + +A+
Sbjct: 206 LTITDFAARAAVFSLLDHPAMNSVYQDGRLATFEHVHLGVAAALDEGLAVPVIRHAERLP 265
Query: 661 IIDL 672
+I+L
Sbjct: 266 LIEL 269
>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=62; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Escherichia coli
(strain K12)
Length = 630
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +1
Query: 379 IPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWM 558
IPH ++ + A RK NE A K DVK++ FI+KAVAAA +++P NS
Sbjct: 423 IPHVTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLS 482
Query: 559 ESFIRQF--SNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
E R +++ VAV TP GL+ P + + +GII+L
Sbjct: 483 EDGQRLTLKKYINIGVAVDTPNGLVVPVFKDVNKKGIIEL 522
>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
component - Deinococcus radiodurans
Length = 525
Score = 64.9 bits (151), Expect = 2e-09
Identities = 41/120 (34%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL GMR IA ++ A+ VN+ K + R+ V + ++ ADVK+S F
Sbjct: 296 VPLRGMRRAIANQMQASHLYTVRTLTVDEVNLTKLVEFRQRVKDE--AKAADVKLSYLPF 353
Query: 499 IIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
I KA+ A K+ P++N+ + E+ I Q S ++ +AVAT GL P + + D + I DL
Sbjct: 354 IFKAITVALKKYPSLNTSFDEATQEIVQKSYYNLGMAVATEAGLTVPVIRDVDRKSIFDL 413
>UniRef50_A5CEC1 Cluster: Putative uncharacterized protein; n=6;
Orientia tsutsugamushi Boryong|Rep: Putative
uncharacterized protein - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 206
Score = 64.9 bits (151), Expect = 2e-09
Identities = 28/66 (42%), Positives = 44/66 (66%), Gaps = 2/66 (3%)
Frame = +1
Query: 472 DVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVS--VAVATPTGLITPXLHN 645
++K+SVND +IK A A RVP +NS W E R++ ++D++ +AVA GL+TP + N
Sbjct: 97 EIKISVNDLLIKITAIALVRVPIINSSWEECGTRKYDSIDIAIGIAVAVKDGLLTPIIRN 156
Query: 646 ADSRGI 663
AD + +
Sbjct: 157 ADKKSL 162
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 64.9 bits (151), Expect = 2e-09
Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P G+R TI +++ +K + PH T ++ + R + R +E DVK++ F+
Sbjct: 253 PYRGIRRTIGEQMAESKYTAPHVTHHDTAVIDSLVETRSKLKARAEAE--DVKLTYMPFV 310
Query: 502 IKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KAV AA K P +NS E I + ++ VAVAT GL+ P + + D + ++++
Sbjct: 311 MKAVVAALKEFPVLNSELREDDEEIALKQDYNIGVAVATDAGLMVPVVEHVDQKSMLEI 369
>UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,
lipoamide acyltransferase; n=9; Chlamydiaceae|Rep: 2-oxo
acid dehydrogenase, E2 component, lipoamide
acyltransferase - Chlamydia muridarum
Length = 410
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+S +R IA L + + +PH L V V+V + + L ER A+ VK+++ F
Sbjct: 186 IPMSPLRRAIASSLRQSSEEVPHASLVVDVDVTDLMNLISLERERFAAAHG-VKLTITSF 244
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAV-ATPTGLITPXLHNADSRGIIDL 672
II+ +A + ++ P +N I V+V VAV G++ P +HN RG++ +
Sbjct: 245 IIQCLAKSLEQFPLLNGSLDGDTIVLKKAVNVGVAVNLNKEGVVVPVIHNCQDRGLVSI 303
>UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Geobacter bemidjiensis Bem|Rep:
Biotin/lipoyl attachment domain-containing protein -
Geobacter bemidjiensis Bem
Length = 361
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 1/172 (0%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR A+PM RR A + L QG+G G + DL
Sbjct: 195 GREKAAPMVRRCARELGVDLAQVQGSGPEGRILLTDLKLQKKESAPAGQAPQAAAEAAPA 254
Query: 298 XXXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
P+S +R +A+ +T + +IPH+ ++V V +++ A+R+ + + +
Sbjct: 255 PQGEG-PRPMSRLRSAVARTVTESWHNIPHFTVTVDVEMDEAEAVRRQLKQ------GGM 307
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITP 633
VSVND I+KAVA A + P +N+ + ++ S++++++AV G++ P
Sbjct: 308 PVSVNDLIVKAVALALSQFPQLNASFTPEGLQFHSDINIAIAVGMSDGVLKP 359
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/117 (33%), Positives = 62/117 (52%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PLS MR+ I +RL ++ + V++ + +R E+ +K +VK+ F
Sbjct: 339 PLSKMRQRIGQRLKDSQNTYALLPTFNEVDMSNVMEIRNKYQEQF-QKKHNVKLGFMSFF 397
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA AA ++ P VN+ I + VD+SVAVATPTGL+ P L N ++ D+
Sbjct: 398 VKAATAALQQQPIVNAVIDGKEIVYRNYVDISVAVATPTGLMVPVLRNTENMSFADV 454
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 63.7 bits (148), Expect = 4e-09
Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R+ IA+++ + + PH V+V K + +RK + LA E+ +K++ F
Sbjct: 203 IPLRGLRKKIAEKMVKSAYTAPHVTGMDEVDVTKLVEIRKNLASELAKEQ--IKLTYLPF 260
Query: 499 IIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IIKAV A K+ P N+ E + I + +A AT GL+ P + +AD + I +L
Sbjct: 261 IIKAVTRALKQYPMFNASLDEETNEIVLKKRYHIGIATATKAGLVVPVIRDADQKSIREL 320
>UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=103;
Proteobacteria|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Shewanella oneidensis
Length = 677
Score = 62.9 bits (146), Expect = 7e-09
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++PLS +++ L +IPH ++ + RK N+ A +KAD K++
Sbjct: 449 EIPLSRIQKISGPNLHRNWVTIPHVTQFDEADITEMEEFRKQQNDAAAKKKADYKITPLV 508
Query: 496 FIIKAVAAACKRVPTVNSHWM---ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
F++KAVA ++ P NS ES I Q + VAV TP GL+ P + + D +GII
Sbjct: 509 FMMKAVAKTLQQFPVFNSSLSSDGESLI-QKKYFHIGVAVDTPNGLVVPVVRDVDKKGII 567
Query: 667 DL 672
+L
Sbjct: 568 EL 569
>UniRef50_A4XHV3 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Caldicellulosiruptor
saccharolyticus DSM 8903|Rep: Catalytic domain of
components of various dehydrogenase complexes -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 460
Score = 62.9 bits (146), Expect = 7e-09
Identities = 34/119 (28%), Positives = 64/119 (53%), Gaps = 1/119 (0%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK-VS 486
+ + PLS +R+TIAK + + + L + + L RK V E EK ++ ++
Sbjct: 232 YEEAPLSNIRKTIAKAMYLSLTTTAQLTLHTSFDASNILEFRKRVKEN--REKLGLEDIT 289
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
+ND I+ AV+ + +N+H+++ +R F NV + AV T GL+ P + N++ + +
Sbjct: 290 INDIILFAVSRVLPKHKALNAHFLDDKMRYFKNVHLGFAVDTERGLMVPTIFNSNKKSL 348
>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
component; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase complex, E2 component - Aeropyrum pernix
Length = 412
Score = 62.9 bits (146), Expect = 7e-09
Identities = 35/117 (29%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G++ ++A+ ++ +K IPH ++ V+ + +R+ + +R A EK V+++ F
Sbjct: 181 IPVRGIKRSMAQSMSLSKSKIPHAYIAEEVDFTELSKLREAL-KRDAEEKG-VRLTYLPF 238
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQF--SNVDVSVAVATPTGLITPXLHNADSRGI 663
+ KAVA A ++ P VNS + E + V++ AV TP GL+ P + N + +G+
Sbjct: 239 VFKAVAKAIRKYPLVNSEFDEEKMEIVVKKAVNIGFAVDTPHGLVVPVVKNVEKKGL 295
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 62.5 bits (145), Expect = 9e-09
Identities = 36/119 (30%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P G+R+TI +T++K + PH V+V + R + R +E D++++ F+
Sbjct: 311 PYKGIRQTIGAAMTSSKYTAPHVTHQDEVDVTALVDARSTL--RREAEAQDIRLTYMPFV 368
Query: 502 IKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA AAA + P VN E+ I + ++ VA AT GL+ P + N D++G++++
Sbjct: 369 MKACAAALQENPQVNVSLDEANEEIVEKQYYNIGVATATDDGLLVPVVENVDAKGLLEV 427
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 62.1 bits (144), Expect = 1e-08
Identities = 38/122 (31%), Positives = 65/122 (53%), Gaps = 4/122 (3%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+ LS +R+TI KR+T + + PH V+V +A R+ + EK ++K++ F
Sbjct: 211 IKLSMLRKTIGKRMTESFYTAPHALCIDEVDVTDLVAYREEMKNHFVEEK-EIKITYLPF 269
Query: 499 IIKAVAAACKRVPTVNSHWMES----FIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
+IKAV A K P N+ E ++++ N + +AV TP GL P + + D +G++
Sbjct: 270 MIKAVMLALKDYPRFNAQLDEENQMLILKKYYN--IGIAVDTPEGLTVPVIKDVDQKGLM 327
Query: 667 DL 672
L
Sbjct: 328 SL 329
>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10947.1 - Gibberella zeae PH-1
Length = 442
Score = 61.7 bits (143), Expect = 2e-08
Identities = 38/118 (32%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S MR TIA RL ++ + V++ +A R E +A E V++
Sbjct: 217 MSRMRRTIAGRLKQSQNTCASLTTIQEVDMSNLIAWRAKYKEEVAEEHG-VRLGYMGAFT 275
Query: 505 KAVAAACKRVPTVNSH--WMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A ++VP +N+ + I VDVS+AV+ P GL+TP L N +S I++L
Sbjct: 276 KATTIAAQKVPQINAQIDTEKEIITYHDYVDVSIAVSAPKGLVTPVLRNTESLSIVEL 333
>UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n=3;
Danio rerio|Rep: UPI00015A4520 UniRef100 entry - Danio
rerio
Length = 494
Score = 61.7 bits (143), Expect = 2e-08
Identities = 28/67 (41%), Positives = 43/67 (64%)
Frame = +1
Query: 472 DVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
++KVSVNDFIIKA A + + +P VN W + + +S+AVAT GLITP + +A
Sbjct: 317 NIKVSVNDFIIKAAAVSLRELPAVNVSWSADGPQPLGFIHISMAVATDRGLITPIIRDAA 376
Query: 652 SRGIIDL 672
+G+ ++
Sbjct: 377 DKGLQEI 383
>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
AceF - Mycoplasma gallisepticum
Length = 440
Score = 61.7 bits (143), Expect = 2e-08
Identities = 35/118 (29%), Positives = 66/118 (55%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+ IAK +T A + IP L+ +V K ++ RK V + + + +VK+S F++
Sbjct: 215 ITSIRKAIAKAMTTAHEEIPATVLTFNFDVTKLVSYRKQVKDAVLASY-NVKLSFLPFLL 273
Query: 505 KAVAAACKRVPTVNSHWMESFIRQF--SNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA+ A P NSH+ ++ R +++ +AV T GL+ P + +A + +I+L
Sbjct: 274 KAITKAVVAHPIFNSHYDKASNRLVLKKKINLGIAVDTADGLMVPNIKSAQDKSVIEL 331
>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
succinyltransferase, putative - Babesia bovis
Length = 402
Score = 61.7 bits (143), Expect = 2e-08
Identities = 39/120 (32%), Positives = 65/120 (54%)
Frame = +1
Query: 313 VDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVN 492
V + ++ MR+ I +RL ++Q+ +++ +A+RK +NE S K VK+
Sbjct: 177 VQVQMTRMRKRIGERLKESQQTTVMLSTFNECDMDAIMALRKELNE---SGKYPVKLGYV 233
Query: 493 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA A ++P +NS+ I VD+SVAVATPTGL+ P + N + + I+L
Sbjct: 234 SAYMKASTMALLKMPIMNSYIEGDDIVTKHFVDISVAVATPTGLVVPVIRNCEGKSWIEL 293
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 61.7 bits (143), Expect = 2e-08
Identities = 30/117 (25%), Positives = 67/117 (57%), Gaps = 2/117 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G+R IA+++ AK+ IPH+ ++V A+R +N++ ++ K+++ F
Sbjct: 202 VPVIGLRRKIAQKMQDAKRRIPHFSYVEEIDVTDLEALRAHLNQKWGGQRG--KLTLLPF 259
Query: 499 IIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
+++A+ A + P +N+ + + + ++ V V +A + GL+ P L +A+SR +
Sbjct: 260 LVRAMVVALRDFPQLNARYDDEAEVVTRYGAVHVGIATQSDNGLMVPVLRHAESRDL 316
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/121 (28%), Positives = 63/121 (52%)
Frame = +1
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
F + +S +R+TI+KRL ++ VN++ +++R + + K K+
Sbjct: 169 FRKIAMSPLRKTISKRLLYTVKNTAMLTTFNEVNMQPIISIRNKYKD-IFENKYKSKLGF 227
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
F +K+V A K+ P +N+ + I D+++A++TP GLITP L N D+ I +
Sbjct: 228 MSFYVKSVTQALKKFPEINASIEKKNIIYHDYYDINIAISTPRGLITPILKNTDNLSIYE 287
Query: 670 L 672
+
Sbjct: 288 I 288
>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
Oceanobacillus iheyensis
Length = 420
Score = 60.9 bits (141), Expect = 3e-08
Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P G R+ IAK++T + +IPH V++ + L RK + K+D +SV F
Sbjct: 196 IPFKGRRKQIAKKMTTSIYTIPHVHHMEEVDMTELLEFRKEI-------KSDADISVAAF 248
Query: 499 IIKAVAAACKRVPTVNS--HWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
IKA+ A K P N+ H + IR + + +A T GLI P + +AD + I
Sbjct: 249 FIKALTIALKEYPIFNAKLHEEKEEIRLEKGIHMGIATDTEEGLIVPVIQSADIKSI 305
>UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=42;
Bacteria|Rep: Dihydrolipoamide acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 548
Score = 60.9 bits (141), Expect = 3e-08
Identities = 37/117 (31%), Positives = 60/117 (51%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PLS +++ L IPH + ++ + A+R +N+ EKA VK ++ F+
Sbjct: 326 PLSRIKKISGANLHRNWVMIPHVTNNDEADITELEALRVQLNKE--HEKAGVKFTMLAFV 383
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IKAV AA K+ PT N+ + V A TP GL+ P + +AD +G++D+
Sbjct: 384 IKAVVAALKKFPTFNASLDGDNLVFKQYYHVGFAADTPNGLVVPVIRDADKKGLVDI 440
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 60.9 bits (141), Expect = 3e-08
Identities = 37/116 (31%), Positives = 57/116 (49%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MR IA+RL ++ + V++ + MRKL + + +K K
Sbjct: 240 MNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMRKLYKDEII-KKTGTKFGFMGLFS 298
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A K +P VN I D+SVAVATP GL+TP + NA+S ++D+
Sbjct: 299 KACTLAAKDIPAVNGAIEGDQIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDI 354
>UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide
S-succinyltransferase, (2-oxogluturate dehydrogenase
complex E2 component), sucB; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Probable
dihydrolipoamide S-succinyltransferase, (2-oxogluturate
dehydrogenase complex E2 component), sucB -
Protochlamydia amoebophila (strain UWE25)
Length = 404
Score = 60.5 bits (140), Expect = 4e-08
Identities = 33/117 (28%), Positives = 61/117 (52%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PLS +R+ IA RL A+Q++ V++ + +++R+ ++ + +K +K+ F
Sbjct: 179 PLSKIRQVIANRLIEAQQTMAMLTTFNEVDLSEIISLREK-HQEIFIKKYGIKLGFMSFF 237
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KAV +A K PTVNS+ + I + D+ +AV T G P + D + +
Sbjct: 238 VKAVVSALKAFPTVNSYLDQQDIVERHYYDIGIAVGTERGTFVPVVRQCDQQSFAQI 294
>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 432
Score = 60.5 bits (140), Expect = 4e-08
Identities = 33/113 (29%), Positives = 57/113 (50%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
+R+ IAK++ + IPH L V +V + +R + + ++ + +S F KAV
Sbjct: 210 VRKAIAKKMVQSVNEIPHAWLMVEADVTNLVQLRNSLKDEFKQQEG-LSLSFFPFFAKAV 268
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
A K+ P +N+ W + I +V++S+AV T L P + AD+ I L
Sbjct: 269 IQALKKNPKINTSWDDGSIIYHKDVNLSIAVTTDEHLYVPVIQQADNYSIAGL 321
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 60.1 bits (139), Expect = 5e-08
Identities = 33/120 (27%), Positives = 64/120 (53%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G+R+ IA+ + +K IPH+ + V+ +A+R+ + E +EK K++
Sbjct: 315 VPMIGIRKKIAENMQRSKHVIPHFTIMDEAKVDAMVALRESLKEH--AEKNGTKITYLPI 372
Query: 499 IIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
I+KA+ A + P N+ ++ I ++ A TP GL+ P + NAD + I+++
Sbjct: 373 IMKALIATIREFPMFNASIDDAAGEIVYKKYFNLGFAADTPNGLVVPVIKNADQKSILEI 432
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 60.1 bits (139), Expect = 5e-08
Identities = 34/118 (28%), Positives = 59/118 (50%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+S +R IA+RL ++Q+ VN++ + +R ++ E VK+ F
Sbjct: 199 VPMSRLRARIAERLLESQQTNAILTTFNEVNMQPVMDLRAKYKDKFEKEHG-VKLGFMSF 257
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA A K+ P VN+ + I D+ +AV +P GL+ P L NAD + ++
Sbjct: 258 FVKAAVHALKKFPLVNASIDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQLSLAEI 315
>UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E2
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 348
Score = 60.1 bits (139), Expect = 5e-08
Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 1/114 (0%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMR-KLVNERLASEKADVKVSVNDFIIKA 510
MR T+AKR++ + S P + ++ V+ + +R KL++ E VK+++ D I+ A
Sbjct: 129 MRATVAKRMSESYFSAPVFTFNIEVDATELKVLRAKLID--TVKESTGVKLTMTDLIVMA 186
Query: 511 VAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
V+ +NS W + I ++ +V++++AV GL P + NA+ + + ++
Sbjct: 187 VSKILPNHQALNSAWTDEGIFRYKDVNIAIAVGLDEGLYVPVVKNANKKSLKEI 240
>UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase, E2 component
- Alcanivorax borkumensis (strain SK2 / ATCC 700651 /
DSM 11573)
Length = 564
Score = 60.1 bits (139), Expect = 5e-08
Identities = 36/115 (31%), Positives = 62/115 (53%), Gaps = 2/115 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
L+ +R+ A+ LT + +IPH ++ A RK N+RL E+ VK+++ F++
Sbjct: 341 LNKLRKVSAQNLTRSWLTIPHVTQHDNADITDLEAFRKSQNKRL--EREGVKLTMLAFLV 398
Query: 505 KAVAAACKRVPTVNSHWMES--FIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
A A A K P NS S + + +++ +AV TP GL+ P + +AD +G+
Sbjct: 399 AACARALKEYPRFNSSLENSGEALIEKRYINIGIAVDTPNGLVVPVIKDADKKGL 453
>UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase
component ofpyruvate deshydrogenase complex; n=1;
Mycoplasma agalactiae|Rep: Dihydrolipoamide
acetyltransferase component ofpyruvate deshydrogenase
complex - Mycoplasma agalactiae
Length = 244
Score = 60.1 bits (139), Expect = 5e-08
Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 2/121 (1%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
+ P+SG+R+ IAK L +S + L + +V +R V +++ +E +VK++
Sbjct: 15 EAPISGIRKAIAKNLKEVLESSAYCSLVLKADVTNLWNLRAKVKDKVFAEH-NVKLTFLS 73
Query: 496 FIIKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
+I+KA A A P+ + W +E + +++ +AV TP GL P + ++ IID
Sbjct: 74 WIVKASAIALSEYPSFAARWDGVEGKVYYPGTLNIGIAVDTPFGLFVPVIRGVENLSIID 133
Query: 670 L 672
+
Sbjct: 134 I 134
>UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1;
Azoarcus sp. BH72|Rep: Putative uncharacterized protein
- Azoarcus sp. (strain BH72)
Length = 237
Score = 60.1 bits (139), Expect = 5e-08
Identities = 39/118 (33%), Positives = 65/118 (55%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL+G+R IA+ + Q +P SV V++ + A+R ER A A K+SVN F
Sbjct: 21 VPLTGLRGAIARNMGQGWQ-VPRVAHSVDVDLTRVEALRA---ERAA---AGDKLSVNAF 73
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
++ AVA A + P +N+ E + ++++ VAVA GL+ P + AD++ + L
Sbjct: 74 VLHAVAQALRAHPRLNALMREKEVELVDDINIGVAVALDDGLMVPVIRQADTKPVAAL 131
>UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Baumannia cicadellinicola str. Hc (Homalodisca
coagulata)|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Baumannia cicadellinicola subsp. Homalodisca coagulata
Length = 358
Score = 59.7 bits (138), Expect = 6e-08
Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 2/121 (1%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++ L +++ + L +IPH N+ K RK N +K ++K+++
Sbjct: 130 EIQLGSIQKKSSSNLYTNWITIPHVTQFHEANITKLEKFRKEQNSTEEIKKLNIKITLLI 189
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSN--VDVSVAVATPTGLITPXLHNADSRGIID 669
F++KAV+ A + P NS E + +++ +AV TP+GL+ P HN + +GII
Sbjct: 190 FVMKAVSKALEIFPLFNSSLSEDGTKLICKKYINIGIAVDTPSGLLVPVCHNVNKKGIIT 249
Query: 670 L 672
L
Sbjct: 250 L 250
>UniRef50_A1UBW5 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=11; Mycobacterium|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 399
Score = 59.7 bits (138), Expect = 6e-08
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
MR +IA ++ +K+ IPHY L+ V ++ LA + ER A+ +V IKAV
Sbjct: 181 MRASIAAAMSRSKREIPHYYLADEVLMDPALAW---LAERNAARSITERVLPAVLQIKAV 237
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVA-TPTGLITPXLHNADSRGIIDL 672
AAA R P N W + V V VA++ GL+ P +H+ R + DL
Sbjct: 238 AAAADRFPEFNGFWRDDAFVGADGVHVGVAISLRGGGLVAPAIHDVPDRSLDDL 291
>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 474
Score = 59.7 bits (138), Expect = 6e-08
Identities = 34/119 (28%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P+ G+R+ + + + + ++PH VTV+V T+ + + + R E +V+VS +
Sbjct: 245 PIKGVRKMMGQAMVQSAFTLPHVTEWVTVDVTATMELVERLKTR--REFREVRVSPLLVL 302
Query: 502 IKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+AV A +R P +NS W ++ + V++ +A ATP GL+ P + +A+S +++L
Sbjct: 303 ARAVMLAMRRTPEINSWWDDAAHEVVYKRYVNLGIAAATPRGLVVPNVKDAESMTLLEL 361
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 59.3 bits (137), Expect = 8e-08
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLA-SEKADVKVSVNDF 498
PLS MR TIA R+ + Q+ QL+ VE + A+ +L N A +E+ KVS D
Sbjct: 199 PLSAMRRTIADRMQQSLQTTA--QLTDVREVEVS-ALVELRNRLAAKAERIGFKVSFTDL 255
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
+KA A A + VP +N I + +V + +AV+ P GLI P + +AD
Sbjct: 256 FLKATALALREVPELNVTVQADRIIEHDHVHLGMAVSVPDGLIVPVVRDAD 306
>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=3; Mollicutes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC27343 / NCTC 10154)
Length = 438
Score = 59.3 bits (137), Expect = 8e-08
Identities = 31/121 (25%), Positives = 66/121 (54%), Gaps = 2/121 (1%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++P++G+R+ K +T + I + ++ +T MR + + A+ + +K++
Sbjct: 212 EVPMNGVRKATVKAMTKSHTEIAAFTGMKNTDITETHKMRTELKDHAAA--SGIKLTYLA 269
Query: 496 FIIKAVAAACKRVPTVN--SHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
FIIKAVA + + +P +N + + I+ N+++ +AV TP GL+ P + AD + +
Sbjct: 270 FIIKAVAKSLRDMPNINVRGDFANNKIQFMHNINIGIAVDTPNGLMVPVIKGADHLSVFE 329
Query: 670 L 672
+
Sbjct: 330 I 330
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 59.3 bits (137), Expect = 8e-08
Identities = 32/118 (27%), Positives = 64/118 (54%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+SG+R+ IAK + +K + PH L V+V +A RK + A + +K++ +++
Sbjct: 217 MSGIRKAIAKAMVNSKHTAPHVTLMDEVDVTNLVAHRKQFKQVAADQ--GIKLTYLPYVV 274
Query: 505 KAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA+ +A K+ P +N+ + + Q ++ +A T GL+ P + NAD + + ++
Sbjct: 275 KALTSALKKFPVLNTSIDDKTDEVIQKHYFNIGIAADTEKGLLVPVVKNADRKSVFEI 332
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 59.3 bits (137), Expect = 8e-08
Identities = 29/119 (24%), Positives = 64/119 (53%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++P++GMR+ IA R+ + + +++ ++ K ++K ++ A E+ K+++
Sbjct: 173 EIPVTGMRKVIAARMQESLANSAQLTITMKADITKLATLQKQLSPT-AEERYGTKLTITH 231
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
F+ +A A + P +NS + I +V + +AVA GL+ P + +A+ +I+L
Sbjct: 232 FVSRAAVLALQAHPVLNSFYQNERIITHPHVHLGMAVALENGLVVPVIRHAEKLSLIEL 290
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 58.8 bits (136), Expect = 1e-07
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 2/117 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R+ IA+R+ +K + PH V++ + +A R E LA+ K +K+S F
Sbjct: 222 IPLRGIRKVIAERMVKSKYTAPHVTTVEEVDMTELMAFRAQAKE-LAARKG-IKLSFMPF 279
Query: 499 IIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
IIKAV AA + P +N+ + I + A+ T GL+ P + +AD + +
Sbjct: 280 IIKAVVAALREFPYLNASIDDEAQEIVLHKRYHIGFALDTDAGLLVPVIKDADRKPV 336
>UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2
component, dihydrolipoamide acetyltransferase; n=2;
Desulfotalea psychrophila|Rep: Probable pyruvate
dehydrogenase, E2 component, dihydrolipoamide
acetyltransferase - Desulfotalea psychrophila
Length = 397
Score = 58.4 bits (135), Expect = 1e-07
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P + MR+ IA + + + IPHY L+ +++ TL + N++ + ++ + V +
Sbjct: 177 PGAAMRQAIATAMARSNREIPHYYLATRIDMSNTLRWLEAENKKRSIKERILPVVP---L 233
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVA-TPTGLITPXLHNADSRGIIDL 672
IKA A A +VP +N +W+++ + V + ++ GL+ P +H+AD + + +L
Sbjct: 234 IKATALALAKVPELNGYWVDNRQQPEEAVHIGFVISLRQGGLVAPAIHHADLKSLPEL 291
>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
catalytic domain - Anaeromyxobacter sp. Fw109-5
Length = 454
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/120 (26%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R+ IA+ + +K++ H+ +V + +++ + +A+++ VK++ F
Sbjct: 226 VPLRGVRKRIAENMARSKRTAAHFTFVEQCDVTELARVKERM--AVAAKEEGVKLTFLPF 283
Query: 499 IIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
++KAV AA ++ P +N+ + + DV +A AT GL+ P + AD R +++L
Sbjct: 284 VVKAVVAALRKHPKLNATMDDERGELVLHRRYDVGIASATDAGLVVPVVRGADRRSLVEL 343
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 58.0 bits (134), Expect = 2e-07
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 11/194 (5%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGGQ-GTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV A P R++A I L TG G + DL
Sbjct: 230 RVLAKPPVRKIARDLGIDLADVVATGARGEVTREDLVSYQAQRDAEVDKADTFWGKSGRP 289
Query: 301 XXTFVD-LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV 477
++ +P+ G+R+ AK + + + PH + V V+ +T+ K + +++ + +
Sbjct: 290 QDQRIERIPVKGVRKATAKAMVESAFAAPHVSIFVDVDASRTMEFVKRL--KVSRDFEGI 347
Query: 478 KVSVNDFIIKAVAAACKRVPTVNSHWMES---------FIRQFSNVDVSVAVATPTGLIT 630
KVS + KAV A R P+VN+ W++S ++ F N + +A ATP GL+
Sbjct: 348 KVSPLLILAKAVIWAAARNPSVNATWVDSADGSDTAEIHVKHFMN--LGIAAATPRGLMV 405
Query: 631 PXLHNADSRGIIDL 672
P + NA + +L
Sbjct: 406 PNIKNAQDLSLKEL 419
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/111 (27%), Positives = 57/111 (51%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P++ +R IA+RL ++ + VN++ + +R + E +K+ F
Sbjct: 199 VPMTRLRMRIAERLVQSQSTAAILTTFNEVNMQAIMDLRARYKDSFEKEHG-IKLGFTSF 257
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
+KAV AA K+ P +N+ + I D+ +AVA+P GL+ P + +AD
Sbjct: 258 FVKAVVAALKKFPIINASVDGNDIIYHDYYDIGIAVASPRGLVVPIIRDAD 308
>UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase; n=3;
Staphylococcus|Rep: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 425
Score = 57.6 bits (133), Expect = 3e-07
Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 5/185 (2%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R++ SP+AR +AE K + + +GTG + D+
Sbjct: 130 RIFISPLARNMAEDKGLDINKIKGTGGNHRITKLDIQRVEANGYDYASDTTSNEDTSHVP 189
Query: 301 XXTF----VDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEK 468
T + L+ MR+ IA+ + + S L V+ ++ L + + L
Sbjct: 190 TQTVDTSAIGEGLNPMRQRIAQNMRQSLNSTAQLTLHRKVDADRLLDFKDRLATELKQAD 249
Query: 469 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
DVK++V + KAV A K +N+ + + + ++ +V + +A + GL+ P +++A
Sbjct: 250 QDVKLTVTTLLAKAVVLALKEYGAMNARYEQGELTEYEDVHLGIATSLDEGLMVPVINHA 309
Query: 649 DSRGI 663
D++ I
Sbjct: 310 DTKSI 314
>UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Novosphingobium aromaticivorans|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Sphingomonas aromaticivorans
Length = 406
Score = 57.6 bits (133), Expect = 3e-07
Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 4/182 (2%)
Frame = +1
Query: 136 SPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXXTF 312
SP+ARRLA + L GTG+ G + D+
Sbjct: 133 SPLARRLAAQNGVDLATVTGTGMGGKISGKDVLAASAKPRPAPVPVSPPRPGSDGEI--- 189
Query: 313 VDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVN 492
+P S R TIA+R+ A +IP + V++ A R+ V AS V
Sbjct: 190 --VPHSLRRRTIAQRMVEAA-AIPTLTADMEVDLTALFARRRSVEGNGAS--------VL 238
Query: 493 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS---RGI 663
I +A AA + +N+HW E + QF V + +AV TP GL+ P + NA+S RG+
Sbjct: 239 GMIAEAAIAALLQHRRLNAHWREDAMVQFGAVHLGIAVDTPEGLVVPVVRNAESLNARGL 298
Query: 664 ID 669
D
Sbjct: 299 TD 300
>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
component; n=2; Alteromonadales|Rep: Apha keto acid
dehydrogenase complex, E2 component - Idiomarina baltica
OS145
Length = 515
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/188 (22%), Positives = 84/188 (44%), Gaps = 4/188 (2%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
G+ ASP RRLA +I + G+G G + D+
Sbjct: 218 GKAVASPAVRRLARENSINIADVPGSGKKGRVLKQDIKDFVAGDKSASQASTQQQTTTPA 277
Query: 298 XXXTFVDLP-LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD 474
+ G++ +AK++ + +IPH+ S ++ +A+R+ + E+ +
Sbjct: 278 QQSGGTRTEAIRGVKAAMAKQMMNSVSTIPHFTYSDEFDLTNLIALREKLKEQYKEQ--G 335
Query: 475 VKVSVNDFIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNA 648
V+++V F IKA++ A K P +N+ + + F + ++ +AV T GL+ P +
Sbjct: 336 VRLTVMPFFIKALSLALKEFPIMNAQVNDDCTEVTYFDDHNIGMAVDTKIGLLVPNVKQV 395
Query: 649 DSRGIIDL 672
++ IID+
Sbjct: 396 QNKSIIDV 403
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/118 (26%), Positives = 63/118 (53%), Gaps = 2/118 (1%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
D+ + G+R IA+ + AK++IPH +++ +R +N + + ++ K+++
Sbjct: 209 DIKVIGLRRKIAENMAHAKRTIPHITYVDEIDLTALEDLRAHMNAKKSDDQ--TKLTIIP 266
Query: 496 FIIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
F++ A+ + + P N+H+ S + Q V +A ATP GL+ P + +A+S I
Sbjct: 267 FLVLALVKSLPKFPQANAHFDTDGSLLTQHDGVHCGIAAATPNGLMVPVIKHAESLDI 324
>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=9; Actinobacteria
(class)|Rep: Catalytic domain of components of various
dehydrogenase complexes - Arthrobacter sp. (strain FB24)
Length = 462
Score = 57.6 bits (133), Expect = 3e-07
Identities = 35/120 (29%), Positives = 67/120 (55%), Gaps = 3/120 (2%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD-VKVSVNDF 498
P+ G+R+ A + ++ + PH +T++V T+ +L++ AS + K++
Sbjct: 236 PIKGVRKLTAAAMVSSAFTAPHATEFLTIDVTPTM---ELLSRLKASRTFEGFKLTPLTL 292
Query: 499 IIKAVAAACKRVPTVNSHWMES--FIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+ KA+ A +R P++NS W E+ I Q++ V++ +A ATP GL P + +A S + +L
Sbjct: 293 VAKALLIALRRQPSLNSRWDEANQEIVQYNYVNLGIAAATPRGLTVPNIKDAHSMSLTEL 352
>UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;
Bacteria|Rep: Dihydrolipoamide acyltransferases -
Thermoanaerobacter tengcongensis
Length = 219
Score = 57.2 bits (132), Expect = 3e-07
Identities = 33/113 (29%), Positives = 61/113 (53%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
MR TI++R+ + IPH + V+V + + +R+ +N+ + K + D I KA
Sbjct: 4 MRRTISQRMKKSWTEIPHVTEDIKVDVTELVNLRENLNK-----SGEHKFTYTDLIAKAC 58
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
A K+ P +N I + N+++ +AVA GLI P + NA+++ +++L
Sbjct: 59 VIALKKNPVLNWSIEGDEIIKNPNINLGIAVALEDGLIVPVVKNAENKSLLEL 111
>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
alpha-keto acid dehydrogenase E2 - Symbiobacterium
thermophilum
Length = 459
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/118 (28%), Positives = 56/118 (47%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ +R IA ++ AK PH + V+V + +R+ + + +S F
Sbjct: 231 IPVDPVRRRIAAKMVQAKHEAPHAWTMMQVDVTNLVKLREQAGPEFRA-RTGRPLSYVPF 289
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IKAV + + P +NS W I ++++SVAVAT L P + +AD I L
Sbjct: 290 FIKAVVESLREYPILNSQWNGDEIVIRQDINISVAVATEDALAVPVIKHADRLSIAGL 347
>UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (E2)
of 2-oxoglutarate dehydrogenase; n=6; cellular
organisms|Rep: Dihydrolipoamide succinyl transferase
(E2) of 2-oxoglutarate dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 369
Score = 57.2 bits (132), Expect = 3e-07
Identities = 32/118 (27%), Positives = 55/118 (46%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+S +R+TIA+ L AA+ + +++ A+R E + ++ F
Sbjct: 142 VPMSRLRQTIARNLKAAQNTAAILTTFNEIDMSAAKALRAQYKEEFEKKHDGARLGFMSF 201
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+AV A K P +N+ I V++ +AV T GL+ P LH+AD +L
Sbjct: 202 FARAVVGALKDYPAINAQIEGDEIVYRDFVNLGIAVGTERGLVVPVLHDADQMSFAEL 259
>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 555
Score = 57.2 bits (132), Expect = 3e-07
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
+V ASP RR+A ++I L QG+G G + DL
Sbjct: 258 KVLASPAVRRVAREQDIDLSNVQGSGEKGRILKCDLTKQPSKASVVSAQTQSDSVGVIQS 317
Query: 301 XX---TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKA 471
T V+ +SG++ +A+++ + +IPH+ +S + ++ +A+R + + + +
Sbjct: 318 KVQGGTRVER-ISGIKAAMARQMKHSVSTIPHFTVSEEIQMDALIALRSQLKDDFSEQ-- 374
Query: 472 DVKVSVNDFIIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHN 645
VK+S F IKA++ A K P +NS + + + F+ ++ AV GL+ P +
Sbjct: 375 GVKLSFMPFFIKALSLALKAYPVINSQVNDDCTQLTYFNEHNIGFAVDGKLGLMVPNIKG 434
Query: 646 ADSRGIIDL 672
I D+
Sbjct: 435 VQDMSIFDI 443
>UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8;
Plasmodium|Rep: Plasmodium vivax PV1H14105_P -
Plasmodium yoelii yoelii
Length = 465
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/103 (28%), Positives = 58/103 (56%), Gaps = 4/103 (3%)
Frame = +1
Query: 376 SIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK-VSVNDFIIKAVAAACKRVPTVNSH 552
SIP + L+ NVEK + +RK + ++ + ++++ +IK ++ K P +NS
Sbjct: 245 SIPLFHLNEIYNVEKIIKIRKEIKNKIIENDIGINNITISSILIKLISNTLKEFPILNSK 304
Query: 553 W---MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+ S++ ++N ++ VA+ TP GL+ P + N + + IID+
Sbjct: 305 FNAKTNSYV-VYNNHNICVAMDTPHGLLVPNIKNVEKKNIIDI 346
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 56.8 bits (131), Expect = 4e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G+R+ IA+ + + IPH + + V+ + R ++ E ++ F
Sbjct: 215 IPVKGVRKAIAQNMVTSVTEIPHGWMMLEVDATNLVKTRNH-HKNSFKENEGYNLTFFAF 273
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
+KAVA A K P +NS W I ++++S+AVA L P + +AD + I
Sbjct: 274 FVKAVAEALKSNPLLNSSWDGEEIILHKDINISIAVADEDKLYVPVIKHADEKSI 328
>UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component; n=1; Mycoplasma
penetrans|Rep: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component - Mycoplasma
penetrans
Length = 478
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/121 (29%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
L ++ MR+ IA + + + + LSV ++V R + + + E +VK+++ F
Sbjct: 252 LEMTSMRKAIANAMKRSWSNAAYTNLSVEIDVTDVWEQRNKIKDYIL-ETENVKLNLLPF 310
Query: 499 IIKAVAAACKRVP---TVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
IIKA+A K+ P +N + I + + V++ +AV T GLI P + NAD II+
Sbjct: 311 IIKAIAKTLKQFPIFNAINDDANGTLILR-NEVNIGIAVDTKDGLIVPNIKNADKLSIIE 369
Query: 670 L 672
+
Sbjct: 370 I 370
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 56.4 bits (130), Expect = 6e-07
Identities = 49/188 (26%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Frame = +1
Query: 133 ASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXXT 309
ASP+AR++A K I L GTG G + D+
Sbjct: 177 ASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKPAEAKAPAAKEEKVVDLAE 236
Query: 310 FVD-LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
V+ P+S MR+ I+K +T + + P + L+ +++ + +A+RK + + + + K +KVS
Sbjct: 237 GVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMIALRKKLIDPIMA-KTGLKVS 295
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSN-------VDVSVAVATPTGLITPXLHN 645
D I AV K + +M + + +N V++ +AV GLI P +H
Sbjct: 296 FTDLIGMAVV---KTLMKPEHEYMNASLINDANDIELHRFVNLGIAVGLDDGLIVPVIHG 352
Query: 646 ADSRGIID 669
AD + D
Sbjct: 353 ADKMSLSD 360
>UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Mycoplasma synoviae|Rep: Dihydrolipoamide
acetyltransferase - Mycoplasma synoviae
Length = 309
Score = 56.4 bits (130), Expect = 6e-07
Identities = 35/115 (30%), Positives = 63/115 (54%), Gaps = 2/115 (1%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
+R+ IAK +T + ++ + L VN+ K +R + + L + DVK++ FI+KAV
Sbjct: 87 IRKAIAKAMTNSWSNVAYTNLVHRVNMTKLWDLRSSIKDSLLKSE-DVKITFLPFILKAV 145
Query: 514 AAACKRVPTVNSHWMES-FIRQFSNV-DVSVAVATPTGLITPXLHNADSRGIIDL 672
+ A K P ++ + E+ F V ++ AV T GL+ P + NA++ ++DL
Sbjct: 146 SVALKEFPLFSAKYNEAKSTLDFPGVINLGFAVDTEAGLMVPVIKNANALSVLDL 200
>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
Drosophila melanogaster (Fruit fly)
Length = 462
Score = 56.4 bits (130), Expect = 6e-07
Identities = 35/119 (29%), Positives = 67/119 (56%), Gaps = 3/119 (2%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
L G+R+ + K +T + + IPH+ S +++ + + R + + +A E K++ F I
Sbjct: 237 LKGVRKAMLKSMTESLK-IPHFAYSDEIDMTQLMQFRNQL-QLVAKENGVPKLTFMPFCI 294
Query: 505 KAVAAACKRVPTVNSHW---MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA + A + P VNS ES + + ++ ++SVA+ TP GL+ P + N ++ II++
Sbjct: 295 KAASIALSKYPIVNSSLDLASESLVFKGAH-NISVAIDTPQGLVVPNIKNCQTKTIIEI 352
>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
- Aspergillus oryzae
Length = 448
Score = 56.4 bits (130), Expect = 6e-07
Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S MR A+RL ++ + ++ K +A+R N+ +K VK+ +
Sbjct: 224 MSRMRLRTAERLKESQNTAAFLTTFNEADMSKIMALRSQ-NKDDVLQKHGVKLGFMGPVA 282
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSN-VDVSVAVATPTGLITPXLHNADSRGIIDL 672
+A A A + +P +N+ F + +D+SVAVATP GL+TP L N + +GI+++
Sbjct: 283 RASALALREIPAINASIENDDTIVFHDYIDLSVAVATPKGLVTPVLRNMERQGIVEI 339
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 56.4 bits (130), Expect = 6e-07
Identities = 33/116 (28%), Positives = 59/116 (50%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S +R+TIA+RL ++ + +++ K +A+R E +K VK+ F +
Sbjct: 177 MSRLRKTIAQRLKDSQNTAAILTTFNEIDMSKVIALRNQYKEEF-EKKHLVKLGFMSFFV 235
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A K +P+VN+ + + D+ VAV T GL+ P + +AD G ++
Sbjct: 236 KATIEALKLIPSVNAEIDGDDLVYKNYYDIGVAVGTEQGLVVPVVRDADKMGFAEV 291
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 56.0 bits (129), Expect = 8e-07
Identities = 32/116 (27%), Positives = 59/116 (50%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S MR IA RL A++ + +++ +R + ++ DVK+ + +
Sbjct: 164 ISSMRRRIADRLKASQNTCAMLTTFNEIDMTPLFQLRDKYKDEF-HKRHDVKLGLMSPFV 222
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A A K VP VN+ + + I VD+++AVATP GL+ P + + + + ++
Sbjct: 223 KASAIALKDVPIVNASFGKDTIDYHEFVDIAIAVATPRGLVVPVIRDVQNMNLANI 278
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 56.0 bits (129), Expect = 8e-07
Identities = 35/122 (28%), Positives = 68/122 (55%), Gaps = 5/122 (4%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLA--SEKADVKVSVND 495
P G+R +I +++ +++ +PH V V + R ERLA +E+ DV ++
Sbjct: 320 PYRGVRRSIGEQMARSRREVPHATHHDQVVVSGLVEAR----ERLAPLAEERDVTLTYTP 375
Query: 496 FIIKAVAAACKRVPTVNSHW---MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
F++K VAAA + P +N+ E + + ++ ++ VA AT GL+ P +++ D +G++
Sbjct: 376 FVVKCVAAALDKHPVLNTALDTENEEIVYRDAH-NIGVAAATDHGLVVPVVNDVDGKGLV 434
Query: 667 DL 672
+L
Sbjct: 435 EL 436
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 56.0 bits (129), Expect = 8e-07
Identities = 38/120 (31%), Positives = 63/120 (52%), Gaps = 4/120 (3%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+ ++ +T +K IP L +NV+ + R + LA K +K++ FI
Sbjct: 320 ITRLRKAVSNAMTRSKSIIPETVLMDEINVDALVNFRNEA-KGLAESKG-IKLTYMAFIA 377
Query: 505 KAVAAACKRVPTVNSHWM----ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAV A K P N+ + E +I++F N+ +AV TP GLI P + NAD + +L
Sbjct: 378 KAVLIALKEFPMFNASFNHDTDEVYIKKFINL--GMAVDTPDGLIVPNIKNADRLSVFEL 435
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 55.6 bits (128), Expect = 1e-06
Identities = 33/120 (27%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R+ IA+++ + +IPH + ++ +R+ + SE+ +K++ F
Sbjct: 186 IPLKGIRKAIAEKMIKSVATIPHVTHVDEIEMDALKELREQLKHY--SEQKGIKLTFLPF 243
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPT--GLITPXLHNADSRGIIDL 672
IKA+ +A K N+ E D + +AT T GLI P + NAD + +++L
Sbjct: 244 FIKAIVSALKEFEYFNASIDEETNEIVLKKDYHIGIATDTEKGLIVPVIQNADQKSLLEL 303
>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Tropheryma whipplei|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/110 (29%), Positives = 57/110 (51%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+ +S +R IA+R + Q+ + V++ + + R + E+ E V ++V F
Sbjct: 233 IKMSRLRNIIAERAVHSMQNTAQLSTVIEVDLTRIVDYRNSIKEKF-KEAEGVNLTVLPF 291
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
II A A ++ P +NSH ++ I ++S+AV T GL+TP + NA
Sbjct: 292 IINATVQALRKYPVINSHIVDDQIVFPDYENISLAVDTERGLLTPVIKNA 341
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/120 (26%), Positives = 66/120 (55%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G+R +A+++ + +IPH V+V + +++R+ + R +E+ VK++ F
Sbjct: 181 IPVRGIRRAVAEKMAKSASAIPHAYHFEEVDVTELVSLRERL--RQEAERLGVKLTYLPF 238
Query: 499 IIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+ KAVA A + P +NS + E I + + AV T GL+ + +AD + ++++
Sbjct: 239 VAKAVAVALREFPMLNSSFDEERGEIVVKRRIHLGFAVDTEQGLMVVVVRDADKKSVLEI 298
>UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=11; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Haemophilus
influenzae
Length = 567
Score = 55.6 bits (128), Expect = 1e-06
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Frame = +1
Query: 379 IPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWM 558
IPH ++ A RK N +K VK++ FI+KAVA A + P NS
Sbjct: 360 IPHVTHFDKADITDLEAFRKEQNALREKQKLGVKITPVVFIMKAVAKALEAYPRFNSSIT 419
Query: 559 ESFIRQF--SNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
E R +++ VAV TP GL+ P N + +GII+L
Sbjct: 420 EDAQRLILKKYINIGVAVDTPNGLVVPVFKNVNKKGIIEL 459
>UniRef50_Q1AT73 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 441
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R IA+R++ +K+ PH V +V + +R+ E + V ++ F++
Sbjct: 215 VTSVRRAIAERMSRSKREAPHAWTLVEADVSGLVGLREARKEEFRRREG-VNLTYLPFVV 273
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTG-LITPXLHNADSRGIIDL 672
+AV + K P +NS W I +++ +AV G LI P + +AD GI+ L
Sbjct: 274 RAVVESLKEHPVLNSVWDGDRIVLRKRINIGIAVDLEEGALIVPVIKDADDYGIVGL 330
>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
component; n=1; marine actinobacterium PHSC20C1|Rep:
Putative dihydrolipoamide acyltransferase component -
marine actinobacterium PHSC20C1
Length = 480
Score = 54.8 bits (126), Expect = 2e-06
Identities = 37/119 (31%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P+ +R+ A + ++ + PH +T++V +T+ +LV + A A SV +
Sbjct: 258 PIKSVRKATAAAMVSSAFTAPHVTEFLTIDVTRTM---ELVAKLKAGGTA---ASVLAVL 311
Query: 502 IKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA+ R P+VNS W + I +F V++ +AVATP GL+ P L +AD + +L
Sbjct: 312 AKALCIGVARNPSVNSRWDAEANEIVEFGYVNLGIAVATPRGLMVPNLKDADMMTLAEL 370
>UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=79; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bartonella quintana (Rochalimaea quintana)
Length = 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/116 (29%), Positives = 59/116 (50%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+TIA+RL A+ + V++ + +RK + L +K VK+ F
Sbjct: 186 MTKLRQTIARRLKDAQNTAAMLTTFNEVDMSAVMDLRKRYKD-LFEKKHGVKLGFMGFFT 244
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAV A K PTVN+ + I + V+ +AV T GL+ P + +AD + ++
Sbjct: 245 KAVCHALKEFPTVNAEIDGTDIVYKNYVNAGIAVGTDKGLVVPVVRDADQMSLAEI 300
>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
Pyruvate dehydrogenase E2 component dihydrolipoamide
acetyltransferase - Mycoplasma mobile
Length = 453
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 2/115 (1%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
+R+ IAK + + ++ + L +NV +++R+ + + + + VKV+ FIIKA+
Sbjct: 231 IRKAIAKAMKNSWSNVAYTNLVNEINVGSLVSLREKIKDSV-QDLTGVKVTFLPFIIKAI 289
Query: 514 AAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
A K P + + + E S + +++ +AV T GL+ P + NAD II++
Sbjct: 290 TLALKEFPVLMAKYDEQASELVYSGTLNIGIAVDTEAGLMVPVIKNADKLNIIEI 344
>UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Succinyltransferase
- Chlamydia trachomatis
Length = 365
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/118 (28%), Positives = 61/118 (51%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S +R+TI++RL + +++ +A+RK E + K VK+ F +
Sbjct: 142 MSAIRKTISRRLVQSLHDSAMLTTFNEIHMGPLIALRKERQEDFVA-KYGVKLGFMSFFV 200
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD--SRGIIDL 672
+AV + K+ P VN++ ++ I D+S+A+ T GL+ P + N D S G I+L
Sbjct: 201 RAVVDSLKKYPRVNAYIEDNEIVYRHYYDISIAIGTDRGLVVPVIRNCDQLSSGEIEL 258
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/117 (28%), Positives = 58/117 (49%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P+S MR+ IA + +K++ H V+ K + +R+ N+ EK +K++ F
Sbjct: 327 PMSVMRKKIADHMVMSKRTSAHVHGVFEVDFTKIVKLREK-NKNSFQEKTGLKLTYTPFY 385
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+AVA A + P +N+ I ++++ +AVA GLI P + AD + L
Sbjct: 386 ARAVAHALRAWPIINASVEGENIHYKKDINLGIAVALDWGLIVPVVKQADGLSFVGL 442
>UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Sulfurovum sp. (strain NBC37-1)
Length = 410
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
MR+ IA ++ + IPHY LS ++N+ L NE+ + ++ + ++ I+AV
Sbjct: 193 MRKAIAAAMSRSNAEIPHYYLSTSINMTPALDWLAEQNEKRSIKERILPAALT---IRAV 249
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVA-TPTGLITPXLHNA 648
A + VP +N W ++ ++ VA+A GL+TP L NA
Sbjct: 250 VKALQAVPELNGFWQNDTLQMSEVINPGVAIAKRKGGLVTPALLNA 295
>UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=47; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Azotobacter vinelandii
Length = 638
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Frame = +1
Query: 316 DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
++P++ + + A L + ++PH + ++ + A R V ++ +EKA VK++V
Sbjct: 412 EVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFR--VAQKAVAEKAGVKLTVLP 469
Query: 496 FIIKAVAAACKRVPTVNSHWMES---FIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
++KA A K +P NS S IR+ V + AV TP GL+ P + N D + ++
Sbjct: 470 LLLKACAYLLKELPDFNSSLAPSGQALIRK-KYVHIGFAVDTPDGLLVPVIRNVDQKSLL 528
Query: 667 DL 672
L
Sbjct: 529 QL 530
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 54.4 bits (125), Expect = 2e-06
Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S R+TIAKRL +Q+ V++ + +RK ++ E+ +VK+ F
Sbjct: 192 MSRRRQTIAKRLVEVQQTSAMLTTFNEVDMTAVMNLRKRRKDQFF-EQNEVKLGFMSFFT 250
Query: 505 KAVAAACKRVPTVNSHWM--ESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
KAV AA K+ P +N+ E +++F D+ +AVA GL+ P + +AD
Sbjct: 251 KAVVAALKKYPLLNAEIQGDELIVKKF--YDIGIAVAAVEGLVVPVVRDAD 299
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 54.0 bits (124), Expect = 3e-06
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P+S +R TIA RL A+Q+ +N+ +A+R + A +K VK+ F
Sbjct: 210 PMSMLRRTIASRLVQAQQTAALLTTFNEINMAPVMAIRSKYKDAFA-KKHGVKLGFMSFF 268
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
KA A +R P VN+ + + D+ +A+ GL+ P L N +
Sbjct: 269 AKATVEALRRYPAVNAEIRGDSMVYRNYQDIGIAIGGGKGLVVPVLRNVE 318
>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 415
Score = 54.0 bits (124), Expect = 3e-06
Identities = 31/109 (28%), Positives = 54/109 (49%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S +R TIA+RL A+Q +++ + +RK + +K ++ + F
Sbjct: 191 MSRLRRTIAQRLVDAQQEAAILSTFNEIDMSAVMNLRKQHKDEF-KDKHEIGLGFMSFFT 249
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
KA A A K P +N+ + I VD+ +AV+TP GL+ P + + D
Sbjct: 250 KATAIALKEFPIMNAQVDGNSIIYHDFVDMGIAVSTPKGLVVPVIRDCD 298
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 53.6 bits (123), Expect = 4e-06
Identities = 34/116 (29%), Positives = 58/116 (50%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+TIA+RL A+ + V++ +A+R + + +K VK+ F
Sbjct: 200 MTKLRQTIARRLKEAQSTAAMLTTFNEVDMSAVMALRTKYKD-VFEKKHGVKLGFMGFFT 258
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAV A K +P VN+ + I + V VAV T GL+ P + +AD I ++
Sbjct: 259 KAVTHALKEIPAVNAEIDGTDIIYKNFAHVGVAVGTEKGLVVPVVRDADQMSIAEI 314
>UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=14; Burkholderia|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Burkholderia pseudomallei
(Pseudomonas pseudomallei)
Length = 483
Score = 53.6 bits (123), Expect = 4e-06
Identities = 27/115 (23%), Positives = 62/115 (53%), Gaps = 2/115 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G+R IA+R+ AK+ IPH+ ++V + A+R +N + + +++V
Sbjct: 257 VPVIGLRRKIAQRMQDAKRRIPHFSYVEEIDVTELEALRAELNRKYGDTRG--RLTVLPL 314
Query: 499 IIKAVAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSR 657
+ +A+ A + P +N+ + + + + V + +A + GL+ P + +A++R
Sbjct: 315 LARAMVIALREFPQINARYDDEAGVVTRHGAVHLGIATQSKAGLMVPVVRHAEAR 369
>UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein - Yarrowia lipolytica
(Candida lipolytica)
Length = 466
Score = 53.6 bits (123), Expect = 4e-06
Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 8/126 (6%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD--VKVSVN 492
+PL+ + + K +T + SIPH+ + V ++K + +R VN LA ++ K+S
Sbjct: 232 VPLTPTQMGMFKTMTNSL-SIPHFLYTDEVCLDKLMELRASVNSLLAKSPSNGVSKISYM 290
Query: 493 DFIIKAVAAACKRVPTVNSHWMES------FIRQFSNVDVSVAVATPTGLITPXLHNADS 654
F IKA++ A K P VN+ S +R + N+ S+A+ TP GL+ P + N
Sbjct: 291 PFFIKALSLALKDYPMVNAKVDLSGDKPAVLMRDYHNI--SIAMDTPNGLLVPTIKNVQD 348
Query: 655 RGIIDL 672
+ I+++
Sbjct: 349 KTIVEI 354
>UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable
dihydrolipoyllysine-residue succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial precursor - Schizosaccharomyces pombe
(Fission yeast)
Length = 452
Score = 53.6 bits (123), Expect = 4e-06
Identities = 35/122 (28%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MR IA+RL ++ ++ +A+RK + + E VK+ F
Sbjct: 225 MNRMRLRIAERLKESQNRAASLTTFNECDMSAVVALRKKYKDEILKETG-VKIGFMSFFS 283
Query: 505 KAVAAACKRVPTVNSHWM-----ESFI-RQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
KA A K++P +N ++ + R F D+S+AVATP GL+TP + NA+S ++
Sbjct: 284 KACTQAMKQIPAINGSIEGEGKGDTLVYRDFC--DLSIAVATPKGLVTPVIRNAESMSLL 341
Query: 667 DL 672
++
Sbjct: 342 EI 343
>UniRef50_Q1AZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 396
Score = 53.2 bits (122), Expect = 6e-06
Identities = 31/111 (27%), Positives = 58/111 (52%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PL + T+A+ +T + +P + V ++ + R+ + ++ V +S D +
Sbjct: 174 PLGDVGRTMARVVTRSWHEVPQFVQMVQLDASALVGRRRELAGQIKRSHG-VDLSYTDLL 232
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
++AVA A P NS ++ I + +V+VSVAVAT +GL+ P + A +
Sbjct: 233 LEAVAGAAGEEPLANSSLVDGEILLYEDVNVSVAVATGSGLLVPVVRWAQA 283
>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
component, dihydrolipoamide succinyltransferase; n=2;
Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
succinyltransferase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 431
Score = 53.2 bits (122), Expect = 6e-06
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P++ +R+ IA+ + + +IP +V+V K + RK E +K ++++ +
Sbjct: 204 PMAPVRKAIARAMDR-QAAIPTVTNFDSVDVRKLVGHRKAFKEMARDDKG-IRLTYLAYA 261
Query: 502 IKAVAAACKRVPTVNSH--WMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA+AA K+ P +N+ I +V++ +AV PTGL P + NAD + I +
Sbjct: 262 VKALAAVAKKFPELNASVDMKAQEIVYHDDVNMGIAVDAPTGLFVPVIKNADRKSIFTI 320
>UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=2;
Apocrita|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Apis mellifera
Length = 501
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/121 (27%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+ G + + K +T + +IPH+ S N+ + + R V + L E + +S F
Sbjct: 274 VPIKGYSKHMWKTMTQSL-NIPHFVYSDECNINRLIDYRNEVKDSLKDE--GISLSFMPF 330
Query: 499 IIKAVAAACKRVPTVNSHWME---SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
IKA + A ++VP +NS W++ +R + ++ +A+ T GLI P + + + II+
Sbjct: 331 FIKAASRALEKVPQLNS-WLDEENQALRVQKSHNIGIAMDTSEGLIVPNIKDVQNLNIIE 389
Query: 670 L 672
+
Sbjct: 390 I 390
>UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Gloeobacter violaceus|Rep: Dihydrolipoamide
S-acetyltransferase - Gloeobacter violaceus
Length = 419
Score = 52.8 bits (121), Expect = 7e-06
Identities = 51/190 (26%), Positives = 83/190 (43%), Gaps = 6/190 (3%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
GR+ ASP ARRLAE + L G+G G + D+
Sbjct: 129 GRIVASPNARRLAEQLGVDLASITGSGPGGRIVGEDVERAAAGAKAPAPAPAAKPASAPA 188
Query: 298 XXXTFV----DLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASE 465
+ S +++ + + + AA +IP +++ T+ + + K V +
Sbjct: 189 PLPAAAASGQPVAFSALQQAVNRNMEAAL-AIPAFRVGYTITTDAFDELHKSVKSK---- 243
Query: 466 KADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPT-GLITPXLH 642
V+V ++KAVA + P + + + ES +R S V+V+VAVA GLITP L
Sbjct: 244 ----GVTVTTMLVKAVAITLAKHPLLFAAYTESGLRYHSAVNVAVAVAMEEGGLITPVLR 299
Query: 643 NADSRGIIDL 672
ADS+ + L
Sbjct: 300 AADSKDLYTL 309
>UniRef50_Q12FH2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Proteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 420
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
MR+ IA ++ +K+ IPHY LS + + + LA NE L + + + +KAV
Sbjct: 186 MRKAIAATMSRSKREIPHYYLSEPIPMARALAWLLQRNEGLPITERILPAVLQ---LKAV 242
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVA-TPTGLITPXLHNADSR 657
AAA +RVP +N + + + + V VA++ GL+ P +H+ ++
Sbjct: 243 AAALQRVPQLNGLYRDGAFQLSTAVHAGVAISLRGGGLVAPAIHDVGAK 291
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 52.8 bits (121), Expect = 7e-06
Identities = 31/115 (26%), Positives = 58/115 (50%)
Frame = +1
Query: 307 TFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVS 486
T + ++ +R TIA+RL ++ + V++ +RK E +K ++K+
Sbjct: 195 TIERVKMTRLRRTIAQRLKDSQNNAAILSTFNEVDMFNVSELRKKYKEEF-EKKHEIKLG 253
Query: 487 VNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
F +KA AA + +P +N+ I + D+ VAV+T +GL+ P + NA+
Sbjct: 254 FMSFFVKAATAALQELPIINAQVDGYDILYHNYCDIGVAVSTNSGLVVPIIRNAE 308
>UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Tribolium
castaneum
Length = 429
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/119 (27%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P+ G ++ + K ++ A + IPH+ S + V + +R+ + + E D+K+S F
Sbjct: 203 PIKGFQKAMVKTMSDALK-IPHFVYSDEIAVTQLSQLRQTLKK--LPETQDLKLSFMPFF 259
Query: 502 IKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IKA + A +R P +N+ E+ + S ++ VA+ T GL P + N ++ II++
Sbjct: 260 IKAASNALQRFPVLNASLDENCENVTYKSEHNIGVAMDTKVGLAVPVIKNVETLSIIEI 318
>UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Sinorhizobium medicae WSM419
Length = 386
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P S MR IA+ + + + PH + R ++LA+ V +S +
Sbjct: 152 IPHSSMRAAIAEHMLNSVMTAPHVTAVFEADFSAVTRHRDEHRKKLAAR--GVNLSYTAY 209
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVAT-PTGLITPXLHNADSRGIIDL 672
++ A AA + VP VNS W E + F ++++ V ++ GL+ P + A + + ++
Sbjct: 210 VVLASLAAMRAVPEVNSRWHEDALETFDDINIGVGISLGGKGLVVPVIRRAQNLSLAEI 268
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/118 (24%), Positives = 59/118 (50%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+S +R+ I++RL +Q+ +N++ + R +K VK+ + F
Sbjct: 115 VPMSRLRKKISERLLNVQQTTAMLTTFNEINMQAVMNYRHDFQNDFV-KKYGVKLGLMSF 173
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
++A AA ++ P +N+ + ++ +AVA+P GL+ P L NA++ D+
Sbjct: 174 FVRAAVAALRQFPVINAMIDGDDVVYRRYCNIGIAVASPRGLVVPILRNAETLSFADI 231
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 52.4 bits (120), Expect = 1e-05
Identities = 34/111 (30%), Positives = 58/111 (52%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL+ MR IA+RL A+ ++ + +RK++NE S + K+
Sbjct: 234 VPLTRMRMRIAERLKLAQTENVMLTTFNECDMSELTKVRKMLNE---SGEVSCKLGFVSA 290
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNAD 651
++A A ++P +NS+ + + VD+SVAVATPTGL+ P + N +
Sbjct: 291 FMRASTLALLKMPIMNSYIDGKEMVTKNYVDISVAVATPTGLLVPVIRNCE 341
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 52.4 bits (120), Expect = 1e-05
Identities = 36/122 (29%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R TI+ L + Q + +V K +R+ VN + K VKVS F
Sbjct: 201 IPLRGIRRTISDNLMRSLQHTAQVTVFDDADVTKLSELREQVN---GARKDGVKVSYLAF 257
Query: 499 IIKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
+KAV+AA + P +N+ E ++++ N + +A+ TP GL+ + +AD + I+
Sbjct: 258 TVKAVSAALRNHPVLNASIDDEKGEIVLKKYYN--IGLAIDTPRGLMVAPVKDADRKSIV 315
Query: 667 DL 672
+
Sbjct: 316 QI 317
>UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
AceF protein - Wigglesworthia glossinidia brevipalpis
Length = 496
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/103 (32%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
Frame = +1
Query: 376 SIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAVAAACKRVPTVNSHW 555
SIPH V++ + + RK N L K VK+++ FIIK+V A K P NS
Sbjct: 291 SIPHVTQFEQVDISELESFRKNQNNTL---KYKVKITILSFIIKSVFFALKEYPLFNSSL 347
Query: 556 MES----FIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+ ++++ N+ +AV+T GL+ P + + D +GII++
Sbjct: 348 SKDKNKLILKKYFNI--GIAVSTDYGLVVPVIFDVDKKGIIEI 388
>UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.
CcI3|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 524
Score = 52.0 bits (119), Expect = 1e-05
Identities = 36/138 (26%), Positives = 70/138 (50%), Gaps = 20/138 (14%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLAS--EKADVKVSVN 492
+P++G+R ++A+ + A+ + PH +TV+ T+A R +R+A+ E +K++
Sbjct: 281 VPVTGIRRSMAQAMVASVSAAPHVTEFLTVDATATMAAR----DRIAALPEFTGIKITPL 336
Query: 493 DFIIKAVAAACKRVPTVNSHWMESF------------------IRQFSNVDVSVAVATPT 618
F+ +A+ A +R P +NS W+E I + V++ +AVA P
Sbjct: 337 LFVARALLIAVRRHPMINSSWVEDAGGGRPENGGRPENGGRPEIHVYDRVNLGIAVAGPR 396
Query: 619 GLITPXLHNADSRGIIDL 672
GL+ P + +A ++ L
Sbjct: 397 GLVVPTIPDAGRLDVVGL 414
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+ + MR+ IA+R+ +K+ PH V +V + R V + +K K++
Sbjct: 224 IEMDRMRKMIAQRMVDSKRISPHVTTFVEADVTNIVMWRNKVKKEF-QQKHGEKITFTPI 282
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTG-LITPXLHNADSRGIIDL 672
I+A+A P VNS I ++++ +A A P+G LI P + NAD ++ L
Sbjct: 283 FIEAIAKTLGDFPLVNSSIEGENIIVKKDINIGMATALPSGNLIVPVIKNADQMNLLGL 341
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 51.6 bits (118), Expect = 2e-05
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 7/123 (5%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIP---HYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
+SG+R+ + +T A +IP H+ + +E+T RK R+ EK K+++
Sbjct: 392 MSGIRKATVRSMTTAWTTIPMVTHFDKADVTAMEET---RKRFGARV--EKEGGKLTMTH 446
Query: 496 FIIKAVAAACKRVPTVNSHW---MESFI-RQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
++K VA A ++ P N+ E I ++F V++ VAV TP GL+ P + +AD +GI
Sbjct: 447 ILMKVVANALRKFPKFNASLDLGAEQVIYKEF--VNIGVAVDTPVGLLVPVVKDADRKGI 504
Query: 664 IDL 672
+L
Sbjct: 505 TEL 507
>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=2; Leishmania|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Leishmania major
Length = 477
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/122 (24%), Positives = 65/122 (53%), Gaps = 4/122 (3%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASE-KADVKVSVND 495
+P++G+R + K ++ A SIP + S + + + +R + + + K K+S
Sbjct: 246 MPITGVRRGMVKTMSQAA-SIPTFTFSEECELTRLMEVRGSLKDVVKERSKGKAKLSFMP 304
Query: 496 FIIKAVAAACKRVPTVNSHW---MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
F +KA + A + P +N+H + +R+ ++ ++ A+ TP GLI P + + + + I+
Sbjct: 305 FFLKAASIALQHHPDINAHCPVDCSALVRKAAH-NIGFAMDTPNGLIVPVVKHVERKSIL 363
Query: 667 DL 672
D+
Sbjct: 364 DI 365
>UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase
complex E2 component; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to 2-oxoglutarate
dehydrogenase complex E2 component - Candidatus Kuenenia
stuttgartiensis
Length = 416
Score = 51.2 bits (117), Expect = 2e-05
Identities = 31/118 (26%), Positives = 59/118 (50%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL R+ A+R+ ++Q+ V++ R+L E A ++ + ++ F
Sbjct: 176 IPLHPKRKITAERMALSRQTAALVTTVFEVDMTPVTKYRELNRE--AMKREGIHLTYLPF 233
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
I AV A K +NS W ++ I Q + +++ +AVA GL+ P + +AD + + L
Sbjct: 234 IAFAVVQALKEHVALNSSWTDNGILQKNYINLGIAVALEDGLVVPVIKDADKKDMFQL 291
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/116 (25%), Positives = 57/116 (49%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+ A+RL ++ + +++ + MRK + +K VK +
Sbjct: 215 MTRIRQRTAQRLKDSQNTAAMLTTFNELDMSALMNMRKTYKDEF-EKKHGVKFGFMSAFV 273
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A K P VN+ E+ I +NV+++VAV+ P GL+ P + N ++ D+
Sbjct: 274 KASTIALKEQPIVNASVEENDIVYHNNVNINVAVSAPRGLVVPVIRNCENLSFADI 329
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
E2 component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNER-LASEKADVKVSVNDFI 501
+S +R+ IA+R+ + Q+ + V+V K +R + LA+E A K++ F
Sbjct: 389 MSRLRKVIAQRMKESLQNSAQLTTVIEVDVTKIARLRARAKDGFLATEGA--KLTFLPFF 446
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNA 648
+KA A K+ P++N+ I + +VS+AV TP GLITP + +A
Sbjct: 447 VKAAVEALKQHPSLNASIDGENIVYHGSENVSMAVDTPKGLITPVIKDA 495
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/113 (26%), Positives = 56/113 (49%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S +R+ IA+RL A+ + V++ +A+R E + ++ ++ F +
Sbjct: 221 MSRLRQRIAQRLKEAQNTAAMLTTFNEVDMTAVMALRSQYKE-VFEKRNHARLGFMSFFV 279
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
KA +A + P VN+ + I + D+ VAV +P GL+ P L AD+ +
Sbjct: 280 KAAISALQEFPAVNAEIQGNEIVFKNYYDIGVAVGSPQGLVVPVLRGADAMSL 332
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/122 (24%), Positives = 64/122 (52%), Gaps = 4/122 (3%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL+G+R+ IA+ + + ++IP + + + R+ + +E+ VK++ +
Sbjct: 210 VPLTGIRKAIAQAMVRSTRTIPQVTHFGEADATRLVQHRRRIQP--LAEQQGVKLTYLAY 267
Query: 499 IIKAVAAACKRVPTVNSHWMES----FIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
++KA+AA K+ P +N+ E I +F + + AV T GL+ P + +AD + +
Sbjct: 268 VVKALAAVLKKYPMLNASLDEEREEIVIHEF--IHIGFAVDTDRGLLVPVIRDADQKSLF 325
Query: 667 DL 672
+
Sbjct: 326 QI 327
>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 441
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/116 (25%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Frame = +1
Query: 331 GMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKA 510
GMR IA+ + A+K++IPH+ ++V MR +N A+ + K+++ F+I A
Sbjct: 220 GMRRRIAENMAASKRAIPHFTYVEEMDVTALEEMRADLN---ANRGSRPKLTMLPFLIVA 276
Query: 511 VAAACKRVPTVNSHWME--SFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+ P +N+ + + + ++ V + +A T GL+ P + +A + + L
Sbjct: 277 ICRTIPEFPMINARYDDEAGVVTRYGAVHLGMATQTDAGLMVPVIRDAQDKNVWQL 332
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/113 (30%), Positives = 58/113 (51%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S MR+ I+ R++ + + P +VT N+ ++ K + L K K++ DF+I
Sbjct: 228 MSSMRKVISARMSESVKISP----TVTYNINIDISELKRLKNNL---KDTFKLTYTDFLI 280
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
K V+AA K+ P VN V++ VAVA GLI P + + D +G+
Sbjct: 281 KIVSAALKQFPLVNCSISGGKFILKDYVNMGVAVALDEGLIVPVVKDTDIKGL 333
>UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component,
dihydrolipamide acetyltransferase; n=4; Geobacter|Rep:
Dehydrogenase complex E2 component, dihydrolipamide
acetyltransferase - Geobacter sulfurreducens
Length = 418
Score = 50.0 bits (114), Expect = 5e-05
Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 1/181 (0%)
Frame = +1
Query: 133 ASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXXT 309
ASP RRLA K I L +G+G G + DL
Sbjct: 138 ASPAVRRLAREKGIDLHQVRGSGPEGRILMEDLDQVAANEEPPAAQAGQVSAGESPAPPE 197
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
P++ MR IA+ A ++IPH+ +V +++++ ++V E S A V+
Sbjct: 198 AE--PMTRMRGAIARITAEAWRTIPHFYETVEIDMKEA---GEIVRELKGSGNA---VTY 249
Query: 490 NDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
ND ++KA A A + P +N+ + + + V++ AVA GL P + S + +
Sbjct: 250 NDLVLKAAALALVQFPRMNASFRDGGVVAHREVNIGFAVAMEEGLQVPVVKGCQSLALKE 309
Query: 670 L 672
+
Sbjct: 310 I 310
>UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=13; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Robiginitalea biformata HTCC2501
Length = 476
Score = 50.0 bits (114), Expect = 5e-05
Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P+S M + IAK + + + H Q V V+V + + R V + + K++
Sbjct: 246 IPMSRMGKLIAKHMAESVSTSAHVQSFVEVDVTRIVEWRDRVKADFEKREGE-KLTFTPI 304
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTG-LITPXLHNADSRGIIDL 672
++AVA A K+ P +N + + +++ +A A P G LI P + NAD ++ +
Sbjct: 305 FMEAVAKALKKFPMMNISVDGDRVIKKKQINLGMAAALPDGNLIVPVIRNADQLNLVGM 363
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 50.0 bits (114), Expect = 5e-05
Identities = 30/119 (25%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+ + MR+ IA+R+ +K++ H V ++ + R+ N++ EK ++ F
Sbjct: 202 IEMDRMRKMIAQRMVDSKKTSAHVTSFVEADMTNIVLWREK-NKQAYREKFGESITYTPF 260
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTG-LITPXLHNADSRGIIDL 672
I+A+A A + P +N I + ++++ +AVA P+G LI P + AD ++ +
Sbjct: 261 FIEAIAKAIRDFPMINISIDGDKIIKKKDINIGMAVALPSGNLIVPVIRKADQLNLVGI 319
>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=1; Gramella forsetii KT0803|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Gramella forsetii
(strain KT0803)
Length = 507
Score = 50.0 bits (114), Expect = 5e-05
Identities = 36/121 (29%), Positives = 63/121 (52%), Gaps = 5/121 (4%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPH-YQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
+SG+R+ AK +AA +IPH +Q + M KL EKAD +++ +
Sbjct: 284 ISGIRKATAKNTSAAWSTIPHVFQFDEADISDIEERMEKL------QEKADGNLTITAIL 337
Query: 502 IKAVAAACKRVPTVNSHW----MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
K A+A ++ P N+ E ++++ V++ +AV T GL+ P + NAD + II+
Sbjct: 338 AKISASALRQFPKFNASIDMENEEMILKKY--VNIGIAVDTEKGLLVPVVRNADQKTIIE 395
Query: 670 L 672
+
Sbjct: 396 I 396
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 49.6 bits (113), Expect = 7e-05
Identities = 31/118 (26%), Positives = 56/118 (47%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P++ +R+ +A RL ++ + V++ + +R + EK VK+ +
Sbjct: 238 VPMTRLRKRVATRLKDSQNTFALLTTFNEVDMTNLMKLRSQYKDAFL-EKHGVKLGLMSG 296
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IKA +A + P VN+ I VD+S+AV T GL+ P + +AD D+
Sbjct: 297 FIKAAVSALQHQPVVNAVIDGDDIIYRDYVDISIAVGTSKGLVVPVIRDADKMNFADI 354
>UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase
component; n=6; Anaplasmataceae|Rep: Dihydrolipoamide
acetyltransferase component - Anaplasma marginale
(strain St. Maries)
Length = 437
Score = 49.2 bits (112), Expect = 9e-05
Identities = 29/110 (26%), Positives = 53/110 (48%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S +R+ IA RL ++ + V++ +A+R E +K +VK+ F I
Sbjct: 213 MSKIRQVIASRLKESQNTAATLSTFNEVDMSAVMALRGKYKEGF-EKKYEVKLGFMSFFI 271
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+AV A + +P +N+ I ++ VAV T GL+ P + A++
Sbjct: 272 RAVVLALREIPVINAEISGDEIIYRDYCNIGVAVGTDKGLVVPVIRGAET 321
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 49.2 bits (112), Expect = 9e-05
Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+ +R A+RLT A +IPH ++ + +R+ ++ +E A K++V +
Sbjct: 390 MRSIRRKTAERLTQAWTTIPHVTQHDRADITELEKLREKFAKQ--AEAAGGKLTVTAIAL 447
Query: 505 KAVAAACKRVPTVNSHW---MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
K +AAA K+ P N+ E I + V + VAV T GL+ P L N D + + +
Sbjct: 448 KVIAAAMKKFPKFNASIDIDREEIIYK-KYVHIGVAVDTEAGLLVPVLRNVDQKNVYQI 505
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 49.2 bits (112), Expect = 9e-05
Identities = 29/117 (24%), Positives = 54/117 (46%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P++ +R IA + A+ + +++ + +RK + L +K V + + F
Sbjct: 219 PMTPIRRRIADHMLQARLNTAMLTTFNEIDMSRLQEIRKQFRD-LFQKKHSVSLGIMSFF 277
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA A A K +P +N+ I + + + VAV GL+ P + + D G DL
Sbjct: 278 LKAAAVALKELPELNAFIEGHEIVYHNYIHIGVAVGAERGLVVPVIRDVDKLGFADL 334
>UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial, putative; n=1; Babesia bovis|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial,
putative - Babesia bovis
Length = 417
Score = 49.2 bits (112), Expect = 9e-05
Identities = 31/116 (26%), Positives = 60/116 (51%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
L+ + + K + A+ + +PH VTV + L K + + + D+K+++ F++
Sbjct: 197 LNSVGRGMVKSMVASLE-VPH----VTVGEDVDLTELKSYYLQKRALETDIKLTMTPFLL 251
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA + A P +NS + + +++VAVAT GL+ P + N +S+ I +L
Sbjct: 252 KAFSLALSENPIMNSKFKGDGYIAYKEHNINVAVATDHGLLVPVIRNVESKSIREL 307
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MR IA+RL A+ + V++ MRK + +K ++K+ +
Sbjct: 235 MNRMRLRIAQRLKEAQNTCAMLTTFNEVDMSNISEMRKTYKDAFL-KKHNIKLGFMSAFV 293
Query: 505 KAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A A P VN ++ I VD+SVAVATP GL+ P + N + D+
Sbjct: 294 KAAAYALADQPAVNGVIDDTTKEIVYRDYVDISVAVATPKGLVVPVIRNVEGMNFADI 351
>UniRef50_A6W003 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Marinomonas|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Marinomonas sp. MWYL1
Length = 414
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/120 (23%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLT-AAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVND 495
+P + MR+ IA + + + PH +++ + + RK+ ++ E+A VK++
Sbjct: 187 VPHTAMRKKIANHMVDSLLHTSPHVTSVFEMDMGRIIEHRKMC--KMGFEEAGVKLTFTA 244
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVAT-PTGLITPXLHNADSRGIIDL 672
+ + A A A ++VP VNS + + + F ++++ V A GLI P + + + ++
Sbjct: 245 YFLAASAKAMQKVPVVNSRFHDDCLEIFEDINIGVGTALGDDGLIVPVVKQVQEKNLFEI 304
>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex (E2)
protein; n=1; Nitrosomonas europaea|Rep: AceF;
dihydrolipoamide acetyltransferase component of pyruvate
dehydrogenase complex (E2) protein - Nitrosomonas
europaea
Length = 453
Score = 48.4 bits (110), Expect = 2e-04
Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 6/122 (4%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
LS +RE L IPH +V A+RK NE + K+++ F+I
Sbjct: 228 LSRIREISGANLHRNWVMIPHVTQFDEADVTDLEALRKNHNE--TRQNNGTKLTILAFLI 285
Query: 505 KAVAAACKRVPTVNSHWMES------FIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
KAV AA K+ P N+ S I+++ ++ A TP GL+ P + +AD +G+I
Sbjct: 286 KAVTAALKKFPEFNASLDNSTTESQLIIKRYYHL--GFAADTPNGLVVPVIRDADQKGVI 343
Query: 667 DL 672
+
Sbjct: 344 GI 345
>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=48;
Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor - Homo
sapiens (Human)
Length = 453
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MR+ IA+RL A+ + +++ MR E +K ++K+ +
Sbjct: 227 MNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFL-KKHNLKLGFMSAFV 285
Query: 505 KAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA A A + P VN+ E R + +D+SVAVATP GL+ P + N ++ D+
Sbjct: 286 KASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFADI 343
>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
Bacillus sp. NRRL B-14911
Length = 391
Score = 48.0 bits (109), Expect = 2e-04
Identities = 48/189 (25%), Positives = 77/189 (40%), Gaps = 6/189 (3%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
R+ ASP R+LA +I + +G+G G + D+
Sbjct: 96 RILASPYTRKLARENDINIDDIEGSGPGGRVVDTDIFRMAGQGDVSAREKESGKIKKDAE 155
Query: 301 XXTFVD---LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKA 471
+ SG R+ A+++ + IPH V+V + R E L +K
Sbjct: 156 RPVAAHDSAISYSGRRKMTAEKMVQSLSLIPHCTHFEDVDVTELSVFR----EEL--KKQ 209
Query: 472 DVKVSVNDFIIKAVAAACKRVPTVNSHWMES--FIRQFSNVDVSVAVATPTGLITPXLHN 645
+ +V++ F IKA++ A KR P NS E I + VAV GLI P + N
Sbjct: 210 EKQVTMTAFYIKALSMALKRFPVFNSRLDEKAGLIHLLPEHHIGVAVNAEDGLIVPVIGN 269
Query: 646 ADSRGIIDL 672
A+ + I ++
Sbjct: 270 AEEKTIAEI 278
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P+ +R+ A + + + PH VTV+V +++ + L R + + V+ +
Sbjct: 191 PIRSVRKQTAAAMVRSAFTAPHVTEFVTVDVTRSVEL--LERLRGLPDFEGLSVTPLSLV 248
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSN--VDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA+ A + P++N+ W E + V++ +A ATP GL+ P + A S +++L
Sbjct: 249 AKAMIVALRENPSLNASWDEENQEIVTKHYVNLGIAAATPRGLVVPNIKEAQSLSLLEL 307
>UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2; unclassified
Gammaproteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - marine gamma
proteobacterium HTCC2143
Length = 568
Score = 48.0 bits (109), Expect = 2e-04
Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 9/191 (4%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
VYA P RRLA + + +GTG G + DL
Sbjct: 272 VYAGPAVRRLAREVGLDIALIKGTGPRGRIIKDDLKLAIKEALTAMPATQPVSGIPAVPD 331
Query: 304 XTF-----VDLP-LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASE 465
F V L LS + A+ + + ++PH N+ R+ + + +E
Sbjct: 332 IDFSKFGEVKLESLSKIHRATAQNMHRSWLNVPHVTQFDDANISDLEEFRQSL--KAEAE 389
Query: 466 KADVKVSVNDFIIKAVAAACKRVPTVNS--HWMESFIRQFSNVDVSVAVATPTGLITPXL 639
+ VK++ F++KA AAA + P N+ H + V++ +AV TP GL+ P +
Sbjct: 390 RRGVKITPLPFLLKACAAALRENPKFNASLHTSGHQLVYKQYVNIGIAVDTPLGLVVPVI 449
Query: 640 HNADSRGIIDL 672
+ D + I +L
Sbjct: 450 RDVDKKSIWEL 460
>UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza
sativa|Rep: Os02g0514700 protein - Oryza sativa subsp.
japonica (Rice)
Length = 497
Score = 48.0 bits (109), Expect = 2e-04
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLAS--EKADVKVSVN 492
+P+ +R+ IA RL K S + + +T N + KL+++ EK VK+ +
Sbjct: 271 VPMPRLRKRIANRL---KDSQNTFAMLITFNEVDMTNLMKLLSDYKDQFVEKHGVKLGLM 327
Query: 493 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
+KA +A + P VN+ I +D+SVAV T GL+ +H+ D+ D+
Sbjct: 328 SCFVKAAVSALQNQPIVNAVIDGDDIIYREYIDISVAVGTSKGLVVLVIHDIDAMNFADI 387
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/116 (23%), Positives = 51/116 (43%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S ++T AK+L + +++ + +RK E+ + K+ F
Sbjct: 198 MSRRKKTAAKKLLEVSNNTAMLTTFNEIDMTNVMDLRKRKKEQFIKDHDGTKLGFMSFFT 257
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA AA K+ P VN+ + D+ VAV+T GL+ P + + D + ++
Sbjct: 258 KAAVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTEDGLLVPFVRDCDKKNFAEI 313
>UniRef50_A4SZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes precursor; n=1; Polynucleobacter
sp. QLW-P1DMWA-1|Rep: Catalytic domain of components of
various dehydrogenase complexes precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 472
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/72 (34%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Frame = +1
Query: 463 EKADVKVSVNDFIIKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPX 636
+K VK+++ F+IKA AA K+ PT N+ E ++++ ++ AV T GL+ P
Sbjct: 295 KKDAVKITLLAFLIKAAVAALKKYPTFNASLDGEELILKKYCHI--GFAVDTNIGLVVPV 352
Query: 637 LHNADSRGIIDL 672
+ NAD +GI+++
Sbjct: 353 IRNADQKGILEI 364
>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-ketoacid dehydrogenase
complex - Dokdonia donghaensis MED134
Length = 439
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
MR+ IA + +K + PH V ++ + + R N+ EK +++ ++AV
Sbjct: 214 MRQMIADHMVYSKHTSPHVTAYVEADLTEMVQWRN-DNKVAFQEKHGERLTFTPLFVEAV 272
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTG-LITPXLHNADSRGIIDL 672
A A + P +N I ++++ +A A P+G LI P + NA+ R ++++
Sbjct: 273 AKAVEEFPMINVSVDGKNIIVKEDINIGMATALPSGNLIVPVVKNANQRNLVEI 326
>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=7; Flavobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Gramella forsetii (strain KT0803)
Length = 438
Score = 47.6 bits (108), Expect = 3e-04
Identities = 31/110 (28%), Positives = 48/110 (43%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S R +A+RL +AK V++ +RK E +K V + F
Sbjct: 206 MSMFRRKLAERLVSAKNDTAMLTTFNEVDMSPIFELRKKYKEEF-KDKHGVSLGFMSFFT 264
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
AV A P VNS + + D+S+AV+ P GL P + NA++
Sbjct: 265 LAVIRALDEYPAVNSMIDGDYQISYDYKDISIAVSGPKGLTVPVIRNAEN 314
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/113 (25%), Positives = 56/113 (49%)
Frame = +1
Query: 334 MRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIKAV 513
MR+ IA+RL ++ + ++ K + +R + + + +K K+ + A
Sbjct: 1411 MRKRIAERLKESQNTCALLTTFNECDMSKAIVLRTELKD-IFQKKYGCKLGFVSLFLYAS 1469
Query: 514 AAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
A K++P VN++ I + +D+SVAVATP GL P + + ++ + L
Sbjct: 1470 TLALKKMPQVNAYIDNDEIVYKNYIDISVAVATPNGLTVPVIRDCQNKNLPQL 1522
>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase; n=3;
Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase - Thermoplasma
volcanium
Length = 400
Score = 47.6 bits (108), Expect = 3e-04
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 12/196 (6%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
G+V ASP RR+A I L +GTG G + DL
Sbjct: 111 GKVLASPAVRRIARENGIDLAKVKGTGDNGRVTLDDLDAYMRGETKAKAPEKPIEAAKPA 170
Query: 298 XXXTFVDLP-------LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERL 456
P + G+R I ++T AKQ +PH+ + V+V M ++
Sbjct: 171 EVPPVQRSPGREEILEMHGLRRIIFDKMTKAKQIMPHFTVVEKVDV---TGMISIIESAK 227
Query: 457 ASEKADVKVSVNDFIIKAVAAACKRVPTVNSHWMES----FIRQFSNVDVSVAVATPTGL 624
+S K KV++ +I + V K+ P +N+ + E+ I+++ N + +AV TP GL
Sbjct: 228 SSGK---KVTITGYIARIVPIVLKQYPYLNAIYDEANRRYLIKKYYN--IGIAVDTPDGL 282
Query: 625 ITPXLHNADSRGIIDL 672
+ +AD + + ++
Sbjct: 283 NVFVVKDADRKSMYEI 298
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 47.2 bits (107), Expect = 4e-04
Identities = 34/116 (29%), Positives = 57/116 (49%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MR IA+RL A+ + +++ + RK N+ +K +K+ I
Sbjct: 259 MNRMRLRIAERLKDAQNTNAMLTTFNEIDMSALIDFRKS-NQESFQKKYGLKLGFMSPFI 317
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
A A A K P VN+ + I VD+SVAVATP GL+ P L + +++ ++
Sbjct: 318 AASAYALKDQPVVNAVIDGTDIVYRDYVDISVAVATPKGLVVPVLRSVENKNFAEI 373
>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex,
mitochondrial - Coccidioides immitis
Length = 484
Score = 47.2 bits (107), Expect = 4e-04
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ MR IA+RL ++ + V++ + RKL E + +K +K+
Sbjct: 257 MNRMRLRIAERLKQSQNTAASLTTFNEVDMSSLMEFRKLYKEDIL-KKTGIKLGFMSAFA 315
Query: 505 KAVAAACKRVPTVNS-----HWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+A A K VP VN+ + ++ + + VD+SVAVAT GL+TP + N ++
Sbjct: 316 RACVLAMKEVPAVNASIEGPNGGDTIVYR-DYVDISVAVATEKGLVTPVVRNVEN 369
>UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2;
Sulfitobacter|Rep: Acetoin dehydrogenase E2 component -
Sulfitobacter sp. NAS-14.1
Length = 223
Score = 46.4 bits (105), Expect = 6e-04
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R IA +T K QL+ + + T M + RL + A K+SV D
Sbjct: 5 VPLKGVRGMIADAMT--KSLATAAQLTHHGSADATALMAE--KTRLGA--AGTKISVEDL 58
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTG-LITPXLHNADSRGIIDL 672
++ AV A K+ P N + VD+SVA+A P L+ P + AD+ + +L
Sbjct: 59 LMLAVVRALKKNPDANGRVEGREVHLSDAVDLSVAIALPGNLLVAPAMFGADAMDVTEL 117
>UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_34,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 419
Score = 46.4 bits (105), Expect = 6e-04
Identities = 49/181 (27%), Positives = 79/181 (43%), Gaps = 4/181 (2%)
Frame = +1
Query: 133 ASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXXXT 309
A+P R LA+ K I L QG+G G + DL
Sbjct: 135 ATPAVRHLAKQKGIDLNKIQGSGQDGRILKTDLEKQTQSPKEQPQSSTKINIKSESASTV 194
Query: 310 FVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSV 489
+ +S ++ + K +T A SIPH L V++ + MR E+L EK ++
Sbjct: 195 ---IKMSDFQKGMQKSMTEAN-SIPHLYLKEEVDLTELAQMR----EQLKKEK---NITF 243
Query: 490 NDFIIKAVAAACKRVPTVNSHW--MESF-IRQFSNVDVSVAVATPTGLITPXLHNADSRG 660
+IK+ + A + P +NS + + F Q S+ +VSVA+ +P GL+ P + N +
Sbjct: 244 MTLLIKSFSLALTKYPILNSTYDPTKQFEYTQHSSHNVSVALDSPKGLVVPNIKNVQNLS 303
Query: 661 I 663
I
Sbjct: 304 I 304
>UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).;
n=3; Amniota|Rep: Apoptosis inhibitor 5 (API-5). -
Gallus gallus
Length = 458
Score = 46.0 bits (104), Expect = 8e-04
Identities = 19/48 (39%), Positives = 32/48 (66%)
Frame = +1
Query: 529 RVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
++P VN+ W RQ ++D+S+AVAT GLITP + + ++GI ++
Sbjct: 297 QMPDVNATWDGEGCRQLQSIDISIAVATDRGLITPIIKDVPAKGIQEI 344
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 46.0 bits (104), Expect = 8e-04
Identities = 34/118 (28%), Positives = 62/118 (52%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
++ +R+TIA ++ + + P +V A+R+ + AS A VK++ F++
Sbjct: 247 MAKIRKTIANQMVMSWTTAPRVTNFDDADVTALEALRQQSKDDYAS--AGVKLTSMSFLV 304
Query: 505 KAVAAACKRVPTVNSHW-MESFIRQFSN-VDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAVA A + P +N+ ME+ + V+V +AV + GL+ P + NAD I ++
Sbjct: 305 KAVALALRNNPAINALIDMENNQVVYKEYVNVGIAVDSERGLVVPNIRNADRLAIPEI 362
>UniRef50_Q5AGX7 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 142
Score = 46.0 bits (104), Expect = 8e-04
Identities = 30/66 (45%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Frame = -1
Query: 674 ERSMMPRESALCXIGVMRPVGVATATLTSTLENCLMK--DSIQCELTVGTRLQAAATALM 501
E S P +SAL IGV+ PVGVATAT TST C + Q T G Q A AL+
Sbjct: 54 EISANPLDSALVTIGVINPVGVATATETSTFLYCSITPCSPNQAAFTSGISTQVLAIALI 113
Query: 500 MKSFTE 483
KS +
Sbjct: 114 NKSLID 119
>UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 490
Score = 46.0 bits (104), Expect = 8e-04
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 6/123 (4%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PL+ + + K++T + SIPH+ + +V+ +MRK N EK D +++ I
Sbjct: 260 PLTPNQSGMFKQMTKSL-SIPHFLYTDSVDFSNLTSMRKKYNA--GREKTD-RITPLPVI 315
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSNV------DVSVAVATPTGLITPXLHNADSRGI 663
IKA++ ++ P +NSH + + ++ VAV +P+GL+ P + N + I
Sbjct: 316 IKAISLTFQQFPLLNSHLDTTSNPNKPQIVLKGSHNIGVAVDSPSGLLVPVIKNVQNHSI 375
Query: 664 IDL 672
L
Sbjct: 376 ASL 378
>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase; n=4;
Geobacter|Rep: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase -
Geobacter sulfurreducens
Length = 392
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/120 (25%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL G+R +IA+ + ++++ ++ + +R+ E+ A E+ ++ F
Sbjct: 164 IPLRGVRRSIARNVMTSQRNTAFVTGMEEADITELWHLRE--REQQAVEQRGTHLTFLPF 221
Query: 499 IIKAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
IKAV A + P +N+ + I + +AV TP GL+ P + N D++ II+L
Sbjct: 222 FIKAVQHALREHPYLNAAIDDVAGEIILKKHYHFGIAVETPDGLMVPVIRNVDAKSIIEL 281
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
P++G+R+ A + + +IP Q S V V+ T M + + R A + ++ +
Sbjct: 284 PVTGVRKRTAAAMVTSATTIP--QASTFVTVDCTATMELIDHLRTTPAFAGLSLTPLVVV 341
Query: 502 IKAVAAACKRVPTVNSHWMESFIRQFSN--VDVSVAVATPTGLITPXLHNADSRGIIDL 672
KAV AA P VN+ W E + + V + +A AT GL+ P + A + +L
Sbjct: 342 AKAVLAALAEFPGVNAQWDEERQQIVTKRYVHLGIAAATDRGLLVPSVKEAHRLSLREL 400
>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
complex E2 component - Vesicomyosocius okutanii subsp.
Calyptogena okutanii (strain HA)
Length = 507
Score = 45.2 bits (102), Expect = 0.001
Identities = 50/192 (26%), Positives = 80/192 (41%), Gaps = 8/192 (4%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXX 297
G +ASP R+LA + L GTG G + DL
Sbjct: 218 GNSHASPSIRKLARELGVNLSYITGTGRKGRILDTDLKSHVKQIITSNNFNSVLPKPPII 277
Query: 298 XXXTFVD---LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEK 468
F + + LS + + K LT SIPH VN+ + A R+ E+ A+
Sbjct: 278 DFSKFGNTETIKLSRINKLSGKHLTTCWLSIPHVTQFDEVNINQMEAYRQ---EQKAN-- 332
Query: 469 ADVKVSVNDFIIKAVAAACKRVPTVNSHWMES----FIRQFSNVDVSVAVATPTGLITPX 636
+K++ FI+KA+ K N+ ES I+++ N + +A+ TP GLI P
Sbjct: 333 -GIKLTPLVFIMKALVRTLKNHLRFNASLDESGENLIIKKYFN--LGIAMDTPKGLIVPV 389
Query: 637 LHNADSRGIIDL 672
+ + + + + DL
Sbjct: 390 IRDVEKKSLTDL 401
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 45.2 bits (102), Expect = 0.001
Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+PL +R AK L A IPH ++ + A R+ + +A +++ F
Sbjct: 212 VPLRSVRRATAKHLARAWAEIPHVSHQDVADITELDAFRR--KHKAEIREAGGALNMIVF 269
Query: 499 IIKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
++KA AA K P N+ E +++ N+ VAV T GLI P + + D + +
Sbjct: 270 VLKAAVAALKAFPGFNASIDPEREEIVFKRYYNI--GVAVDTDRGLIVPVIRDVDRKSVR 327
Query: 667 DL 672
+L
Sbjct: 328 EL 329
>UniRef50_Q7SH25 Cluster: Putative uncharacterized protein
NCU02704.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU02704.1 - Neurospora crassa
Length = 562
Score = 45.2 bits (102), Expect = 0.001
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 12/130 (9%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLAS----EKADVKVS 486
+PL+ +E + K +T + +IPH+ + V+ + +R +N L+ E K+S
Sbjct: 319 VPLTRTQEMMFKSMTRSL-TIPHFLYADEVDFTPLVELRTRLNRVLSKSGLPEGQVSKLS 377
Query: 487 VNDFIIKAVAAACKRVPTVN--------SHWMESFIRQFSNVDVSVAVATPTGLITPXLH 642
FIIKAV+ A + P +N S+ S + + S ++ VA+ TP+GL+ P +
Sbjct: 378 YLPFIIKAVSMALYKYPVLNARVELDSNSNGKPSLVMR-SQHNIGVAMDTPSGLLVPVIK 436
Query: 643 NADSRGIIDL 672
N S I+ +
Sbjct: 437 NVGSLNILSI 446
>UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 480
Score = 45.2 bits (102), Expect = 0.001
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKAD--VKVSVNDF 498
L+ +++ + K +T + +IP + + ++ K +R +N++LAS + K+S F
Sbjct: 245 LTPVQQQMFKVMTKSL-AIPQFLYTDEIDFTKLSQVRGRINKQLASSPVNGVAKLSYLPF 303
Query: 499 IIKAVAAACKRVPTVNSHW------MESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
IIKAV+ P +N+ + + D+ +A+ TPTGL+ P L +A S
Sbjct: 304 IIKAVSLTLNHYPILNARLDIDPTSQKPILTMRPQHDIGIAMDTPTGLLVPVLKHAQS 361
>UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 433
Score = 44.8 bits (101), Expect = 0.002
Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 2/185 (1%)
Frame = +1
Query: 124 RVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXX 300
RV ASP AR+LA+ N+ L G+G G + + D+
Sbjct: 128 RVVASPYARKLAKDLNVDLNSITGSGPGGRIVAKDVEAAAAAPKKAAPVAAARPDVPLGS 187
Query: 301 XXTFVDLPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK 480
+P + M+ ++K + + ++P +++ T + A+ K + +
Sbjct: 188 T-----VPFTTMQGAVSKNMVESL-AVPTFRVGYTFTTDALDALYKKIKPK--------G 233
Query: 481 VSVNDFIIKAVAAACKRVPTVNSHWMESFIRQF-SNVDVSVAVATPTGLITPXLHNADSR 657
V+++ + KA A A + P +NS + + S+++++VAVA GLITP L +AD
Sbjct: 234 VTMSALLAKATAMALVQHPVINSSCRDGKSFTYNSSINIAVAVAIDGGLITPVLPDADKL 293
Query: 658 GIIDL 672
I L
Sbjct: 294 DIYSL 298
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 44.4 bits (100), Expect = 0.003
Identities = 32/121 (26%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEK-ADVKVSVND 495
+P+ G+R+ AK + + + +T +V T+ +LVN A + ++VS
Sbjct: 239 VPVRGVRKVTAKAVKDSLDTKALVTAFLTCDVTPTM---ELVNRLRADRRFKGLRVSPLT 295
Query: 496 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
KAV A R P +N+ W ++ I ++++ +A ATP GL+ P + +A +++
Sbjct: 296 VWCKAVCLAMGRTPIINAAWDDAADQIVFRDHINLGIAAATPRGLMVPVVRDAQDMAMLE 355
Query: 670 L 672
L
Sbjct: 356 L 356
>UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase;
n=16; Cyanobacteria|Rep: Dihydrolipoamide
S-acetyltransferase - Prochlorococcus marinus
Length = 460
Score = 43.6 bits (98), Expect = 0.004
Identities = 30/119 (25%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Frame = +1
Query: 319 LPLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDF 498
+P + +++ + + + + S+P +++ + +K A K V + V++
Sbjct: 241 IPFNTLQQAVNRNMEMSL-SVPCFRVGYAITTDKLDAFYKQVKPK--------GVTMTAL 291
Query: 499 IIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPT-GLITPXLHNADSRGIIDL 672
+ KAV R P +N+ W + ++V+VAVA GLITP L NAD + +L
Sbjct: 292 LAKAVGKTLARHPQLNAAWSNEGMTYPKQINVAVAVAMEEGGLITPVLQNADLTDLFEL 350
>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex -
Psychrobacter arcticum
Length = 578
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Frame = +1
Query: 436 KLVNERLASEKAD-VKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQF--SNVDVSVAV 606
+L +E KA+ + +++ FI+KA A A + P NSH + + +V++ +AV
Sbjct: 387 QLRSELKGGMKAEGIGLTILAFIVKATAYALTQHPRFNSHLSDDNTQVILRKSVNMGIAV 446
Query: 607 ATPTGLITPXLHNADSRGI 663
AT GLI P + NA +GI
Sbjct: 447 ATDDGLIVPVIKNAHEKGI 465
>UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr18 scaffold_59, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 428
Score = 43.6 bits (98), Expect = 0.004
Identities = 45/191 (23%), Positives = 85/191 (44%), Gaps = 9/191 (4%)
Frame = +1
Query: 127 VYASPMARRLAEIKNIRLGGQ-GTGLYGSLKSGDLXXXXXXXXXXXXXXXXXXXXXXXXX 303
+ ASP A++LA+ N+ LG G+G G + + D+
Sbjct: 138 IVASPYAKKLAKELNVDLGNVVGSGPMGRIVAKDVEAAAAAGVSVAAEDPKPSPSSAPVK 197
Query: 304 X---TFVDL----PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLAS 462
T ++L P + M+ +++ + + ++P +++ T+ + A+ K + +
Sbjct: 198 APASTGIELGTVVPFTTMQGAVSRNMVDSL-TVPTFRVGYTITTDALDALYKKIKSK--- 253
Query: 463 EKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQF-SNVDVSVAVATPTGLITPXL 639
V++ + KA A A + P VNS + + S+++++VAVA GLITP L
Sbjct: 254 -----GVTMTALLAKATALALVKHPVVNSSCRDGKSFTYNSSINIAVAVAIDGGLITPVL 308
Query: 640 HNADSRGIIDL 672
+AD I L
Sbjct: 309 QDADKVDIYSL 319
>UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase,
carboxy-end; n=2; cellular organisms|Rep:
Dihydrolipoamide S-acetyltransferase, carboxy-end -
Sulfolobus solfataricus
Length = 177
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/66 (30%), Positives = 37/66 (56%)
Frame = +1
Query: 475 VKVSVNDFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADS 654
+K++ D ++K VA + P +N+ I+ V++ +AVA GLI P + NAD+
Sbjct: 1 MKITYTDILVKVVAKLLRDHPYLNATLEGDQIKIIEEVNIGIAVALDQGLIVPVIRNADT 60
Query: 655 RGIIDL 672
+ I ++
Sbjct: 61 KPITEI 66
>UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex
subunit, putative; n=2; Theileria|Rep: 2-oxoglutarate
dehydrogenase complex subunit, putative - Theileria
annulata
Length = 422
Score = 43.2 bits (97), Expect = 0.006
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Frame = +1
Query: 340 ETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKL---VNERLASEKADVKVSVNDFIIKA 510
E + K + A+ + +PH + +V + + K V + +++ K+++ FIIK+
Sbjct: 181 EAMVKSMVASLE-VPHVTVGEECDVTSLIQLYKSYRNVPAEGSDQESQPKITITPFIIKS 239
Query: 511 VAAACKRVPTVNSHWM-------ESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
++ A ++VP +NS + S + N ++SVA+ T GL+ P + N + I +
Sbjct: 240 ISLALEKVPIINSKFNTANAGKGPSSYFLYKNHNISVAINTKNGLMVPNIKNVNKLTIRE 299
Query: 670 L 672
+
Sbjct: 300 I 300
>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
complex, dihydrolipoamide acetyltransferase component;
n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
multienzyme complex, dihydrolipoamide acetyltransferase
component - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 583
Score = 42.7 bits (96), Expect = 0.008
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PLS +++ + L IP ++ A R +N+ +EK+ K+++ FI
Sbjct: 357 PLSRIKKISGQNLARNWVMIPAVTYHEDADITDLEAFRVAINKE--NEKSGKKLTMLAFI 414
Query: 502 IKAVAAACKRVPTVNSHW------MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGI 663
IKA A ++ P N+ M +++ N+ + A TP GL+ P + NAD + +
Sbjct: 415 IKASVRALQQFPEFNTSLDASGGEMSLVYKKYFNI--AFAADTPNGLVVPVIKNADRKSV 472
Query: 664 IDL 672
++
Sbjct: 473 FEI 475
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 42.7 bits (96), Expect = 0.008
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 2/118 (1%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
L+ + AK L+ + Q IPH ++ RKL + + KV++ +
Sbjct: 224 LNKLSRVSAKNLSLSWQVIPHVTQHDLADITDLETARKLFISK--PNYSGPKVTMTALAM 281
Query: 505 KAVAAACKRVPTVNSHW--MESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA+A A P+ NS + I + +++ VAV T GL+ P + + D + II +
Sbjct: 282 KAIAIALHEYPSFNSSFDSQTDEIVYKNYINIGVAVDTENGLVVPVVKDVDKKNIITI 339
>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=3; Trypanosoma|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Trypanosoma brucei
Length = 439
Score = 42.7 bits (96), Expect = 0.008
Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Frame = +1
Query: 328 SGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADV----KVSVND 495
+G+R+ + +T A S+P + V V + L + ++ + L S V KVS+
Sbjct: 207 TGLRKAMVSSMTKAG-SVPSFTACDEVEVSQLLNFQHILRDALNSSSEGVRDGSKVSLMP 265
Query: 496 FIIKAVAAACKRVPTVNSHWMESFIRQFSNV--DVSVAVATPTGLITPXLHNADSRGIID 669
IKA + + + P +N+H + F + A+ TP GL+ P + + + + +
Sbjct: 266 LFIKAASQSLLQYPELNAHVSSECDKLFVKKAHHIGFAMDTPKGLVVPVVRDVQQKSVAE 325
Query: 670 L 672
L
Sbjct: 326 L 326
>UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransferase;
n=1; Tetrahymena thermophila SB210|Rep: 2-oxo acid
dehydrogenases acyltransferase - Tetrahymena thermophila
SB210
Length = 462
Score = 42.7 bits (96), Expect = 0.008
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 3/119 (2%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFII 504
+S ++ + K +T A +IPH L ++ +R+ + + + ++ F I
Sbjct: 230 MSDFQKGMQKSMTEAN-TIPHLYLKDEYDLTNLTVLREQIKK-----SQNQSITFMTFFI 283
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFS---NVDVSVAVATPTGLITPXLHNADSRGIIDL 672
KA + A K P +NS + + +++ N ++S+AV +P GL+ P + N + I+D+
Sbjct: 284 KAFSLALKEYPILNSLYDVNKPFEYTLVQNHNISLAVDSPKGLVVPNIKNVQNLSILDI 342
>UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransferase,
putative; n=1; Aspergillus fumigatus|Rep: 2-oxo acid
dehydrogenases acyltransferase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 460
Score = 42.7 bits (96), Expect = 0.008
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 6/121 (4%)
Frame = +1
Query: 328 SGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK-VSVNDFII 504
S M +T+ + LT IPH+ + + + A+RK +LAS+ D K V+ F+I
Sbjct: 237 SQMFKTMTRSLT-----IPHFLYADELKINDITALRK----KLASDPKDPKKVTFLPFVI 287
Query: 505 KAVAAACKRVPTVNSHWMESFIRQFSNV-----DVSVAVATPTGLITPXLHNADSRGIID 669
KAV+ A P +N+ S + + ++ VA+ TP GLI P + + +R I++
Sbjct: 288 KAVSLALNEYPLLNAKVDLSIPEKPKLIMRPKHNIGVALDTPQGLIVPNIKDVANRTIME 347
Query: 670 L 672
+
Sbjct: 348 I 348
>UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9;
Eurotiomycetidae|Rep: Dihydrolipoamide transacylase -
Aspergillus oryzae
Length = 476
Score = 42.7 bits (96), Expect = 0.008
Identities = 33/122 (27%), Positives = 64/122 (52%), Gaps = 6/122 (4%)
Frame = +1
Query: 325 LSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVK-VSVNDFI 501
L+ ++ + K +T + +IPH+ + +N+ A+RK +LA++ D + ++ F+
Sbjct: 248 LTPIQSQMFKTMTRSL-NIPHFLFADELNINNITALRK----KLANDPKDPRRITFLSFV 302
Query: 502 IKAVAAACKRVPTVN-----SHWMESFIRQFSNVDVSVAVATPTGLITPXLHNADSRGII 666
IKAV+ A P +N S+ + + ++ VA+ TP GLI P + + +R I
Sbjct: 303 IKAVSLALNEYPILNAKVDTSNPDKPQLIMRPRHNIGVAMDTPQGLIVPNVKDVANRSIE 362
Query: 667 DL 672
D+
Sbjct: 363 DV 364
>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Thermoplasmatales|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Picrophilus torridus
Length = 386
Score = 42.7 bits (96), Expect = 0.008
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 1/116 (0%)
Frame = +1
Query: 328 SGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFIIK 507
SG+R+ I ++T +KQ IPH+ ++ ++ E + K ++ S+K VS F K
Sbjct: 173 SGIRKIIFDKMTKSKQIIPHFTITDFISTEN---IEKAID--YYSKKG--YVSFTSFFAK 225
Query: 508 AVAAACKRVPTVNSHWMESFIRQF-SNVDVSVAVATPTGLITPXLHNADSRGIIDL 672
A A K P +N+ + + ++ +AV +P GL + + D + I ++
Sbjct: 226 ACTIAFKEFPKMNALYNDDGTYTIKKRYNIGIAVDSPYGLTVVVVKDVDKKSIFEI 281
>UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=5;
Legionellales|Rep: Pyruvate dehydrogenase E2 component -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 550
Score = 41.5 bits (93), Expect = 0.018
Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVNERLASEKADVKVSVNDFI 501
PL+ +++ + + +IPH ++ A RK +E +++ D K+++ F+
Sbjct: 326 PLNKIKKLTGTNVHRSWITIPHVTQFDEADITDLEAFRKSESE--SAKNQDYKLTLLAFV 383
Query: 502 IKAVAAACKRVPTVNSHWMES----FIRQFSNVDVSVAVATPTGLITPXLHNADSRGIID 669
V A P N+ S +++ N+ +AV TP GL+ P + N D +ID
Sbjct: 384 CSVVCKALHAYPQFNASLDTSGENLIYKKYYNI--GIAVDTPNGLVVPVIKNVDKLSVID 441
Query: 670 L 672
+
Sbjct: 442 I 442
>UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Shewanella frigidimarina NCIMB
400|Rep: Dihydrolipoyllysine-residue succinyltransferase
- Shewanella frigidimarina (strain NCIMB 400)
Length = 252
Score = 41.5 bits (93), Expect = 0.018
Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 10/127 (7%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMRKLVN-ERLA-----SEKADVKV 483
PL+ +R IA + + IPH V++ A+R +N E A +E+A +
Sbjct: 21 PLTKIRRIIANNVLESWTHIPHVTHHDEVDIGAIEALRHKLNIEHSADVLGVTEEAQIHF 80
Query: 484 SVNDFIIKAVAAACKRVPTVNSHWMES----FIRQFSNVDVSVAVATPTGLITPXLHNAD 651
++ FI+KA A K P N+ + ++ + N+ +AV T GL+ P + N D
Sbjct: 81 TLLPFILKATIEALKLFPAFNASLSDDGETLMLKHYYNL--GIAVDTSNGLLVPVIKNVD 138
Query: 652 SRGIIDL 672
+ + +L
Sbjct: 139 ALTLEEL 145
>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=12; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Mycobacterium bovis
Length = 553
Score = 41.5 bits (93), Expect = 0.018
Identities = 50/198 (25%), Positives = 78/198 (39%), Gaps = 14/198 (7%)
Frame = +1
Query: 121 GRVYASPMARRLAEIKNIRLGG-QGTGLYGSLKSGD-LXXXXXXXXXXXXXXXXXXXXXX 294
G Y +P+ R+LA NI L G GTG+ G ++ D L
Sbjct: 240 GAPYVTPLVRKLASENNIDLAGVTGTGVGGRIRKQDVLAAAEQKKRAKAPAPAAQAAAAP 299
Query: 295 XXXXTFVDLP-LSGMRETIAK--RLTAAKQSIPHYQLSVTVNVEKT--LAMRKLVNERLA 459
P L+ +R T K R+ + L T + +T + M K+V R
Sbjct: 300 APKAPPAPAPALAHLRGTTQKASRIRQITANKTRESLQATAQLTQTHEVDMTKIVGLRAR 359
Query: 460 S-----EKADVKVSVNDFIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPT 618
+ E+ V ++ F KAV A K P +N+ + E I + + AV T
Sbjct: 360 AKAAFAEREGVNLTFLPFFAKAVIDALKIHPNINASYNEDTKEITYYDAEHLGFAVDTEQ 419
Query: 619 GLITPXLHNADSRGIIDL 672
GL++P +H+A + L
Sbjct: 420 GLLSPVIHDAGDLSLAGL 437
>UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1;
Marinobacter sp. ELB17|Rep: 2-oxoglutarate dehydrogenase
E2 - Marinobacter sp. ELB17
Length = 250
Score = 40.7 bits (91), Expect = 0.032
Identities = 17/38 (44%), Positives = 26/38 (68%)
Frame = +1
Query: 322 PLSGMRETIAKRLTAAKQSIPHYQLSVTVNVEKTLAMR 435
P+ GM+ +AKR+ AA SIPH+ S ++V + LA+R
Sbjct: 208 PIKGMKAVMAKRMVAAASSIPHFIFSEDIDVTELLALR 245
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 492,546,010
Number of Sequences: 1657284
Number of extensions: 8256866
Number of successful extensions: 21441
Number of sequences better than 10.0: 272
Number of HSP's better than 10.0 without gapping: 20648
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21266
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52066120554
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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