Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30456
(648 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 177 2e-43
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 165 6e-40
UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,... 165 1e-39
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 162 6e-39
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 157 2e-37
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 127 2e-28
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 122 6e-27
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 122 8e-27
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 122 1e-26
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 119 5e-26
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 116 7e-25
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 113 3e-24
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 106 5e-22
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 105 9e-22
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 104 2e-21
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 104 2e-21
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 102 6e-21
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 102 9e-21
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 100 3e-20
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 98 1e-19
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 96 7e-19
UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 95 1e-18
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 95 2e-18
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 94 2e-18
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 94 3e-18
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 92 9e-18
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 87 3e-16
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 85 2e-15
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 84 2e-15
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 83 4e-15
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 83 6e-15
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 83 6e-15
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 80 4e-14
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 80 4e-14
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 79 7e-14
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote... 79 7e-14
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 78 2e-13
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 77 3e-13
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 77 4e-13
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 77 5e-13
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 76 6e-13
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 76 6e-13
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 75 1e-12
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 75 1e-12
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin... 75 1e-12
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 74 3e-12
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha... 74 3e-12
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 74 3e-12
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 73 5e-12
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 73 6e-12
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 72 1e-11
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 71 3e-11
UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1; Proch... 70 6e-11
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 70 6e-11
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 66 9e-10
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 65 2e-09
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 65 2e-09
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 64 3e-09
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 64 4e-09
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 63 6e-09
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 63 6e-09
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 62 1e-08
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 61 2e-08
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 61 3e-08
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 61 3e-08
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 59 8e-08
UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1; Therm... 58 2e-07
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 42 4e-07
UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12; Bacteria|... 57 4e-07
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 56 1e-06
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 56 1e-06
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 55 2e-06
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 55 2e-06
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 53 5e-06
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 52 2e-05
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 52 2e-05
UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha s... 50 5e-05
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 49 8e-05
UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alp... 49 1e-04
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 48 1e-04
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 47 3e-04
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 46 6e-04
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 46 6e-04
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 46 6e-04
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 46 8e-04
UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7; Mycoba... 46 8e-04
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 46 0.001
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 45 0.002
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 45 0.002
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 44 0.002
UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate... 44 0.003
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 43 0.006
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 41 0.022
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 40 0.039
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.052
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 39 0.12
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 39 0.12
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 38 0.16
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 38 0.16
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 38 0.21
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 38 0.21
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 38 0.28
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 37 0.37
UniRef50_A2C5U8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 37 0.37
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 36 0.64
UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily ... 36 0.64
UniRef50_UPI00004D6EAE Cluster: Ras and Rab interactor 1 (Ras in... 36 0.84
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 36 0.84
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 36 1.1
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 36 1.1
UniRef50_Q0AAD2 Cluster: Riboflavin biosynthesis protein RibF; n... 34 2.6
UniRef50_A3DC57 Cluster: Methyl-accepting chemotaxis sensory tra... 34 2.6
UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginali... 34 3.4
UniRef50_Q9Y149 Cluster: Mediator of RNA polymerase II transcrip... 34 3.4
UniRef50_UPI0000F2D933 Cluster: PREDICTED: similar to doublecort... 33 4.5
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 33 4.5
UniRef50_A0TJ86 Cluster: Putative uncharacterized protein; n=1; ... 33 4.5
UniRef50_A7S2A1 Cluster: Predicted protein; n=1; Nematostella ve... 33 4.5
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 33 4.5
UniRef50_A1D894 Cluster: Mating-type protein, putative; n=1; Neo... 33 4.5
UniRef50_Q5WCD3 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
UniRef50_Q6QXE3 Cluster: ORF24; n=1; Agrotis segetum granuloviru... 33 7.9
UniRef50_A2DM79 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 177 bits (431), Expect = 2e-43
Identities = 84/147 (57%), Positives = 106/147 (72%)
Frame = +1
Query: 178 ITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRR 357
+ V+ V+A + + ++ EATF+ KP+KLHKLD GP + +T EDA+ Y Q+ +RR
Sbjct: 11 VPTVSPSVMAISVRLAST-EATFQTKPFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRR 69
Query: 358 IETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLG 537
+E+A+GNLYKEK +RGFCHLYSGQEA AVG +AAM D+ +TAYRCHGWTYL G SV
Sbjct: 70 MESAAGNLYKEKKVRGFCHLYSGQEACAVGTKAAMDAGDAAVTAYRCHGWTYLSGSSVAK 129
Query: 538 VLSELTGRRTGCSRGKGGSMHFVRTHF 618
VL ELTGR TG GKGGSMH +F
Sbjct: 130 VLCELTGRITGNVYGKGGSMHMYGENF 156
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 165 bits (402), Expect = 6e-40
Identities = 74/120 (61%), Positives = 89/120 (74%)
Frame = +1
Query: 259 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 438
+K + L+ GP L+ EDAL +Y Q+ LRR ET +GN YKE+ IRGFCHLY+GQEAV
Sbjct: 43 FKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAV 102
Query: 439 AVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
AVGM+ +R DSVITAYRCH WTYLMGVS+ +++EL G RTGCSRGKGGSMH F
Sbjct: 103 AVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAELFGVRTGCSRGKGGSMHMYSDKF 162
>UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 378
Score = 165 bits (400), Expect = 1e-39
Identities = 71/121 (58%), Positives = 94/121 (77%)
Frame = +1
Query: 256 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 435
P+KLHKL++GP ++ LT ++AL Y ++ +RR+ETA+ LYK K +RGFCHLYSGQEA
Sbjct: 165 PFKLHKLEEGPKKTSVLTKDEALDYYHKMQTIRRMETAAATLYKSKEVRGFCHLYSGQEA 224
Query: 436 VAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTH 615
AVG+ + + D+VITAYR HGW YL GV++ GVL+ELTGRRTGC++GKGGSMH +
Sbjct: 225 CAVGISSVLTPDDAVITAYRAHGWAYLRGVTLHGVLAELTGRRTGCAKGKGGSMHMYCKN 284
Query: 616 F 618
F
Sbjct: 285 F 285
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 162 bits (394), Expect = 6e-39
Identities = 76/167 (45%), Positives = 106/167 (63%)
Frame = +1
Query: 118 IIDKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATS 297
++ +S+++ A+ + +VA+ EATF+IK +H+L++GP T
Sbjct: 4 MLSLLSRVLKGPAQKPVTGAANEAVRVMVASRNYADFASEATFDIKKCDVHRLEEGPPTQ 63
Query: 298 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 477
A LT E L+ Y + +RR+E S LYK+KIIRGFCHLY GQEA VG+ AA+ D
Sbjct: 64 AVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLEAAINPTDH 123
Query: 478 VITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
+ITAYR HG++Y GVSV +L+ELTGRR GC++GKGGSMH +F
Sbjct: 124 LITAYRAHGYSYTRGVSVKEILAELTGRRGGCAKGKGGSMHMYAKNF 170
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 157 bits (382), Expect = 2e-37
Identities = 74/163 (45%), Positives = 107/163 (65%)
Frame = +1
Query: 130 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 309
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 310 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 489
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 490 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH +F
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNF 160
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 127 bits (307), Expect = 2e-28
Identities = 68/158 (43%), Positives = 91/158 (57%), Gaps = 3/158 (1%)
Frame = +1
Query: 154 AKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKL 330
AK + V KY+ T ++ Y+ LD T +T T E+ LKL
Sbjct: 41 AKLMISKFFNPVAGKTFNRLNKYAFSS-VTINLEGYQTKMLDGFKLPTQSTATKEELLKL 99
Query: 331 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWT 510
Y+ + ++R+IE A LYK++ IRGFCHLY GQEAV G+ AA D++ITAYRCH
Sbjct: 100 YKDMNVMRKIELACDKLYKQREIRGFCHLYDGQEAVISGIEAACNLEDAIITAYRCHCHA 159
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVR--THF 618
Y G + +++EL GR+TG + GKGGSMHF R THF
Sbjct: 160 YTRGDTPHQIIAELMGRKTGSTGGKGGSMHFYRKKTHF 197
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 122 bits (295), Expect = 6e-27
Identities = 58/118 (49%), Positives = 79/118 (66%)
Frame = +1
Query: 256 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 435
P+ H L + P+ S +SE+ L + + +RR+E A+ +LYK K+IRGFCHLY GQEA
Sbjct: 43 PFTSH-LCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEA 101
Query: 436 VAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVR 609
+AVGM AA+ D++IT+YR H G ++ SEL GR+TGCS GKGGSMHF +
Sbjct: 102 LAVGMEAAITKKDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYK 159
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 122 bits (294), Expect = 8e-27
Identities = 58/111 (52%), Positives = 74/111 (66%)
Frame = +1
Query: 286 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 465
P S + L++Y+ + I+RR+E A LYK K IRGFCHL GQEA+AVG+ A+
Sbjct: 70 PDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAIT 129
Query: 466 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
DS+IT+YRCHG+T++ G SV VL+EL GRR G S GKGGSMH F
Sbjct: 130 KLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGF 180
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 122 bits (293), Expect = 1e-26
Identities = 58/110 (52%), Positives = 72/110 (65%)
Frame = +1
Query: 271 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 450
K D T A + ED LK Y ++ ++RR E +G LY I GFCHLY GQEAV VGM
Sbjct: 20 KKDFAGGTIAEFSKEDDLKAYREMLLIRRFEEKAGQLYGMGFIGGFCHLYIGQEAVVVGM 79
Query: 451 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ A+++ D VIT YR HG G+S GV++ELTGRR G S+GKGGSMH
Sbjct: 80 QLALKEGDQVITGYRDHGHMLACGMSARGVMAELTGRRGGLSKGKGGSMH 129
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 119 bits (287), Expect = 5e-26
Identities = 54/102 (52%), Positives = 71/102 (69%)
Frame = +1
Query: 265 LHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 444
LH+L++GP A LT E L+ Y + +RR+E + LYK+KIIRGFCHLY GQEA A
Sbjct: 5 LHRLEEGPPEKAELTREQGLQYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQEACAA 64
Query: 445 GMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 570
G+ AA+ +D +ITAYR HG+T+ GVSV +L+ELTG G
Sbjct: 65 GIEAAITPSDHLITAYRAHGYTFTRGVSVKEILAELTGETGG 106
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 116 bits (278), Expect = 7e-25
Identities = 56/120 (46%), Positives = 77/120 (64%)
Frame = +1
Query: 259 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 438
++ + LD P + T T +LY ++++RR+E A+ LYKE+ IRGFCHL +GQEAV
Sbjct: 54 FETYNLDPPPYSLET-TKSQLKQLYYDMSLIRRMELAADKLYKEQKIRGFCHLSTGQEAV 112
Query: 439 AVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
AVG+ + D VITAYR HG+T + G SV ++ EL GRR G GKGGS+H +F
Sbjct: 113 AVGVEHGISPEDKVITAYRAHGFTLMRGGSVKSIIGELLGRRDGICHGKGGSVHMFTKNF 172
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 113 bits (273), Expect = 3e-24
Identities = 52/120 (43%), Positives = 76/120 (63%), Gaps = 1/120 (0%)
Frame = +1
Query: 247 EIKPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYS 423
E+ +K+H++++ T AT T + L Y+ + ++RR+E S LYK K IRGFCHLY
Sbjct: 30 ELPKFKVHRIEESELPTKATTTKSELLNYYKDMALMRRVEIVSDMLYKNKWIRGFCHLYD 89
Query: 424 GQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHF 603
GQE++ VGM AA+ D +I AYR H G + +++E+ R TG S+GKGGSMH+
Sbjct: 90 GQESITVGMEAALTMEDHIINAYRDHTTAMGRGHTSYEIIAEMMQRSTGSSKGKGGSMHY 149
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 106 bits (254), Expect = 5e-22
Identities = 55/120 (45%), Positives = 72/120 (60%), Gaps = 4/120 (3%)
Frame = +1
Query: 253 KPYKLHKL---DQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 420
KP+KLH D P T+AT +E K E + +RR+E+ YK K IRGFCHLY
Sbjct: 21 KPFKLHTAGRDDVPPVPTTATYDTEQMKKCLEMMFRIRRMESLCDQSYKLKKIRGFCHLY 80
Query: 421 SGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
GQEA+ VGM + D ++TAYR H W + G + V +E+ G+ GCS+GKGGSMH
Sbjct: 81 IGQEAIPVGMENVLTLEDLIVTAYRDHAWYIVRGGTPGEVFAEMFGKEGGCSKGKGGSMH 140
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 105 bits (252), Expect = 9e-22
Identities = 52/101 (51%), Positives = 67/101 (66%), Gaps = 1/101 (0%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA-DSVITA 489
E+ L+ Y ++ ++RR E G LY +I GFCHLY GQEAVAVG++AA++ DSVIT
Sbjct: 37 EELLEFYRRMLMIRRFEERCGQLYGLGLIAGFCHLYIGQEAVAVGLQAALQPGRDSVITG 96
Query: 490 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRT 612
YR HG G+ V++ELTGR +G S GKGGSMH T
Sbjct: 97 YREHGHMLAYGIDPKIVMAELTGRASGISHGKGGSMHMFST 137
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 104 bits (249), Expect = 2e-21
Identities = 57/139 (41%), Positives = 73/139 (52%), Gaps = 4/139 (2%)
Frame = +1
Query: 205 ATNAKYSTKKEATFEIKPYKLH---KLDQGPATSATLTSEDALKLYEQLTI-LRRIETAS 372
AT TK +P+KLH + D P + + + LK L +RR+E+
Sbjct: 5 ATRCLLDTKTVPLKPQRPFKLHTAGRTDMAPLPTQAVYDAEQLKQSLALMFRIRRMESLC 64
Query: 373 GNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSEL 552
YK K IRGFCHLY GQEA+ GM + D +IT YR HGW G V +E+
Sbjct: 65 DQSYKLKKIRGFCHLYIGQEAIPAGMENVLTFEDPIITGYRDHGWYISRGGKPEDVFAEM 124
Query: 553 TGRRTGCSRGKGGSMHFVR 609
GR+ GCS+GKGGSMH R
Sbjct: 125 FGRQGGCSKGKGGSMHMYR 143
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 104 bits (249), Expect = 2e-21
Identities = 46/83 (55%), Positives = 62/83 (74%)
Frame = +1
Query: 352 RRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSV 531
+R+E A+ LYK+K IRGFCHL +GQEAVAVG+ + D +ITAYR HG+T++ G S+
Sbjct: 81 QRLEIAADALYKQKKIRGFCHLSTGQEAVAVGIEYGISKEDKLITAYRSHGFTFMRGGSI 140
Query: 532 LGVLSELTGRRTGCSRGKGGSMH 600
+ ++ EL GR+ G S GKGGSMH
Sbjct: 141 MSIVGELLGRQDGISHGKGGSMH 163
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 102 bits (245), Expect = 6e-21
Identities = 49/106 (46%), Positives = 65/106 (61%)
Frame = +1
Query: 283 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 462
G + L+ E + Y + ++RR E +G LY +I GFCHLY GQEAV VG+ M
Sbjct: 9 GRSNGPALSPETMKRAYRDMLLVRRFEEKAGQLYGMGLIGGFCHLYIGQEAVVVGIGLNM 68
Query: 463 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ D IT+YR HG + G++ GV++ELTGR G S GKGGSMH
Sbjct: 69 KQGDKSITSYRDHGQMLVAGMTPRGVMAELTGRSGGYSHGKGGSMH 114
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 102 bits (244), Expect = 9e-21
Identities = 50/103 (48%), Positives = 66/103 (64%)
Frame = +1
Query: 295 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 474
+A LT ++LY + +RR E S Y+ K I GF HLY GQEAVAVG + M + D
Sbjct: 28 NADLTPAARIELYRTMVRIRRFEERSLRAYQAKKIGGFLHLYIGQEAVAVGCCSLMGEHD 87
Query: 475 SVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHF 603
VITAYR HG +G+ +++EL G+ TGCS+GKGGSMH+
Sbjct: 88 HVITAYRDHGHAIAVGMDTKALMAELYGKATGCSKGKGGSMHY 130
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 100 bits (239), Expect = 3e-20
Identities = 46/96 (47%), Positives = 63/96 (65%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 492
E AL++ EQ+ +RR E Y++K I GFCH Y GQEAVAVG A + D+ +T+Y
Sbjct: 7 EKALQMLEQMIRVRRFEEGCLKSYQQKFITGFCHTYIGQEAVAVGAMAHLTPTDAYVTSY 66
Query: 493 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
RCH + G++ V++E+ G+ TGC RGKGGSMH
Sbjct: 67 RCHAQGLIGGLTSREVMAEMFGKITGCVRGKGGSMH 102
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 98.3 bits (234), Expect = 1e-19
Identities = 45/94 (47%), Positives = 64/94 (68%)
Frame = +1
Query: 319 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 498
AL + + +RR+E LY E+ IRGF HLY G+EAVAVG A++ D+V+ YR
Sbjct: 21 ALAVLAGMLRIRRMEEKCAQLYGEQKIRGFLHLYIGEEAVAVGALRALQPQDNVVATYRE 80
Query: 499 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
HG L G+++ G+++E+ G+R GCSRG+GGSMH
Sbjct: 81 HGHALLRGLAMNGIMAEMYGKREGCSRGRGGSMH 114
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 95.9 bits (228), Expect = 7e-19
Identities = 43/102 (42%), Positives = 63/102 (61%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 492
+ A+ +Y+Q+ +R ++ A YK K IRGFCHL GQE + + AM D D +++Y
Sbjct: 37 DKAVYIYKQMMRMRCMDEAMDREYKRKNIRGFCHLSIGQEGIYAALEYAM-DGDVAVSSY 95
Query: 493 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
RCHG Y+ G S+L ++ E+ GR+ G +GKGGSMH F
Sbjct: 96 RCHGIAYVTGCSILEIMGEVLGRQAGVCKGKGGSMHLYNKSF 137
>UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=1; Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E1
alpha subunit - Nyctotherus ovalis
Length = 136
Score = 95.1 bits (226), Expect = 1e-18
Identities = 45/128 (35%), Positives = 76/128 (59%), Gaps = 1/128 (0%)
Frame = +1
Query: 199 VVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASG 375
++ ++A++++ E ++ Y++ LD+ T A ++ LK Y + RR+E
Sbjct: 11 IIGSSARFASTVE--IKLPQYEVFNLDKSILPTKAQTNRDEMLKYYHDMNFQRRVEIMCD 68
Query: 376 NLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELT 555
+YK+K +RGFCHL GQEAV+VG+ A + D +ITAYRCHG G + +++E+
Sbjct: 69 EIYKKKEVRGFCHLMDGQEAVSVGVEAGITKEDHLITAYRCHGVLLGRGETAARLIAEMM 128
Query: 556 GRRTGCSR 579
G+ TG S+
Sbjct: 129 GKATGASK 136
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 94.7 bits (225), Expect = 2e-18
Identities = 46/101 (45%), Positives = 62/101 (61%)
Frame = +1
Query: 298 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 477
A L + LK++EQ+ + R E + Y + I GF HLYSGQEAVAVG AA+R D
Sbjct: 7 AILPDSELLKMHEQMVLSREFEESCAEQYTKGHITGFLHLYSGQEAVAVGATAALRKDDY 66
Query: 478 VITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+++AYR H + G V++EL G+ TG +GKGGSMH
Sbjct: 67 ILSAYREHAQAIVRGAEPRRVMAELFGKATGMCKGKGGSMH 107
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/120 (40%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
Frame = +1
Query: 247 EIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG 426
E Y+ + D + ++ L L + + RR E +Y+ + I GF HLY G
Sbjct: 126 ETVTYETYPADTYGHDELGIADDEVLDLLRNMLLQRRFENRCRQMYQRQKISGFLHLYIG 185
Query: 427 QEAVAVG-MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHF 603
QEAV+ G + A DSVITAYR HG MG++ ++EL G+ TGCS+GKGGSMHF
Sbjct: 186 QEAVSTGSVNAIELGDDSVITAYRDHGMGLAMGITPEAGMAELFGKETGCSKGKGGSMHF 245
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 93.9 bits (223), Expect = 3e-18
Identities = 47/103 (45%), Positives = 64/103 (62%), Gaps = 1/103 (0%)
Frame = +1
Query: 295 SATLTSEDAL-KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 471
SA TS D L +LY ++ ++R E A +++ I G+ H+Y+GQEAVA G A R+
Sbjct: 19 SAVATSPDRLAELYGKMVLIRAFEDACQRAFRQGKIGGYLHVYTGQEAVATGFLEAFREG 78
Query: 472 DSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
D VIT YR H L+G V++EL G+RTG +GKGGSMH
Sbjct: 79 DRVITGYRDHAHALLLGCDPKEVMAELFGKRTGLVKGKGGSMH 121
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 92.3 bits (219), Expect = 9e-18
Identities = 43/100 (43%), Positives = 59/100 (59%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
L + + Y Q+ ++RR E +Y I GF HLY G+EA AVG AA+R D +
Sbjct: 21 LDAATLIDYYRQMVLIRRFEEKCQEMYTRAKIGGFLHLYIGEEATAVGAIAALRPDDHIF 80
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHF 603
T YR HG G+ + +++EL G+ TGCS+G GGSMHF
Sbjct: 81 THYRDHGHAIARGLDINALMAELFGKVTGCSKGLGGSMHF 120
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 87.4 bits (207), Expect = 3e-16
Identities = 41/106 (38%), Positives = 59/106 (55%)
Frame = +1
Query: 286 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 465
P T + ++ LK + ++ +RR E + Y I GF HLY GQEA+AVG++ AM+
Sbjct: 11 PETLTSAGKDETLKAFREMLRIRRFEETAARAYTRGKISGFLHLYIGQEAIAVGVKLAMQ 70
Query: 466 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHF 603
D V+ YR HG+ G ++EL G+ TG G GGSMH+
Sbjct: 71 ANDRVVGTYRDHGYALAQGSDANACMAELFGKATGLVGGVGGSMHY 116
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 84.6 bits (200), Expect = 2e-15
Identities = 44/97 (45%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Frame = +1
Query: 328 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 507
L E + R +E A LY GF HLY+GQEAV+ G+ +R D+V++ YR H
Sbjct: 261 LLEDMLTGRMVEDACARLYYMGKTAGFVHLYTGQEAVSAGVIKLLRPDDAVVSTYRDHVH 320
Query: 508 TYLMGVSVLGVLSELTGRRTGCSRGKGGSMH-FVRTH 615
GV V V++EL G+ TGCSRG+GGSMH F + H
Sbjct: 321 ATSKGVPVREVMAELFGKATGCSRGRGGSMHMFSKKH 357
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 84.2 bits (199), Expect = 2e-15
Identities = 41/104 (39%), Positives = 58/104 (55%)
Frame = +1
Query: 289 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 468
+T L + L LYE + + R E +Y + + GF HLY+GQEAV+ G+ +
Sbjct: 16 STGLNLNKSNLLVLYEDMLLGRNFEDMCAQMYYKGKMFGFVHLYNGQEAVSTGVIKLLNP 75
Query: 469 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
D V + YR H GV V++EL G+ TGCS+G+GGSMH
Sbjct: 76 TDYVCSTYRDHVHALSKGVPSKNVMAELFGKETGCSKGRGGSMH 119
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 83.4 bits (197), Expect = 4e-15
Identities = 42/106 (39%), Positives = 58/106 (54%), Gaps = 1/106 (0%)
Frame = +1
Query: 286 PATSATLTSEDALKLY-EQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 462
PA D L+ Y + ++RR E + +Y+ I G+CHL G+EA VG+ AM
Sbjct: 29 PADRLAQEPPDKLRAYYRMMQLIRRFEERAAEMYQRAKIGGYCHLNLGEEATVVGLMDAM 88
Query: 463 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
D + T YR HG+ G+ V++EL GR TG S+G GGSMH
Sbjct: 89 APHDYLFTTYREHGYALARGIDPGRVMAELFGRTTGVSKGWGGSMH 134
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 83.0 bits (196), Expect = 6e-15
Identities = 44/111 (39%), Positives = 60/111 (54%)
Frame = +1
Query: 268 HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 447
H + A S T T ED L++Y Q+ +R E + LY + G H+YSG+EAVAVG
Sbjct: 5 HLREDTMAKSKTNT-EDYLRMYRQMVRIRTFEDNANQLYLSAKMPGLTHMYSGEEAVAVG 63
Query: 448 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ A+ D D + + +R HG G + EL G+ G RGKGGSMH
Sbjct: 64 ICEALTDDDRITSTHRGHGHCVAKGAEFKEMFCELLGKEEGYCRGKGGSMH 114
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 83.0 bits (196), Expect = 6e-15
Identities = 44/109 (40%), Positives = 59/109 (54%)
Frame = +1
Query: 274 LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 453
L + P +A + + L L+E + LR E + +L+ + +++G HL GQEAVA G
Sbjct: 9 LPERPTFTAEVNGRE-LDLFELMVRLRFFERRAHDLFLQGLVKGTSHLSLGQEAVATGFA 67
Query: 454 AAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
AAM D YR H T G S+ GV+ EL GR G GKGGSMH
Sbjct: 68 AAMEPTDLTFATYRGHAHTLSRGASMTGVMGELMGRSVGLMAGKGGSMH 116
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 80.2 bits (189), Expect = 4e-14
Identities = 40/101 (39%), Positives = 57/101 (56%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
L E + + + +RR E L+K + GF HLY G+EAVAVG +A+R+ D +
Sbjct: 2 LGEEKLVGMLRLMLRIRRFEEKLAELFKRGKLPGFVHLYIGEEAVAVGACSALREDDRIT 61
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFV 606
+ +R HG G V +++EL G+ G RGKGGSMH V
Sbjct: 62 STHRGHGHVIAKGADVSRMMAELLGKEAGYCRGKGGSMHTV 102
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 80.2 bits (189), Expect = 4e-14
Identities = 37/98 (37%), Positives = 58/98 (59%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 492
E+ L Y L ++RR+E A Y E+ +R HL GQEAVAVG+ ++ +D + +++
Sbjct: 14 EELLTFYRSLLLIRRVEEAIAERYTEQEMRCPTHLCIGQEAVAVGVCKMLQQSDGIFSSH 73
Query: 493 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFV 606
R H G + +++EL G+ TGC G+GGSMH +
Sbjct: 74 RAHSHYLAKGGDLKAMIAELYGKSTGCCGGRGGSMHLI 111
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 79.4 bits (187), Expect = 7e-14
Identities = 36/99 (36%), Positives = 55/99 (55%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
+K +Q+ ++R E Y E ++ GF H Y+GQEAVA A V ++YRCH
Sbjct: 32 IKFLKQMVLIREFEARGEEAYLEGLVGGFYHSYAGQEAVATAAIANTGLDPWVFSSYRCH 91
Query: 502 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
L+ + + + +EL G+ TGC+ G+GGSMH +F
Sbjct: 92 ALAILLNIPLQEIAAELLGKETGCALGRGGSMHMCGPNF 130
>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Sphingomonas wittichii RW1
Length = 334
Score = 79.4 bits (187), Expect = 7e-14
Identities = 37/107 (34%), Positives = 60/107 (56%)
Frame = +1
Query: 280 QGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 459
+G A + + ++LY ++ +R E + G L+ I GF HL GQE V+VG+ A+
Sbjct: 10 RGAAHGRNARAPELIELYRRMVTIREAEKSCGALFAAGEIPGFIHLSDGQEGVSVGVMAS 69
Query: 460 MRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R D++ + +R HG G+ + G EL G+ G +G+GGSMH
Sbjct: 70 LRADDTIASTHRGHGHALAKGLGLDGFFRELMGKADGACKGRGGSMH 116
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 78.2 bits (184), Expect = 2e-13
Identities = 38/102 (37%), Positives = 56/102 (54%)
Frame = +1
Query: 295 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 474
S + +D KLY ++ +R ++ + +Y +IRGFCHL GQE V + R+ D
Sbjct: 21 SCKIRYDDVEKLYRKMLCMRYMDESISKMYSRGLIRGFCHLDIGQEEVYAALCHVARN-D 79
Query: 475 SVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
I +YRCH + V ++ EL GR G ++GKGGSMH
Sbjct: 80 KFIGSYRCHALAVAAEIPVREIVGELLGRAGGVAKGKGGSMH 121
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 77.4 bits (182), Expect = 3e-13
Identities = 35/99 (35%), Positives = 58/99 (58%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
++ E A +Y+ + +R E + + I GF HLY+G+EA+A G+ A + D D +
Sbjct: 39 VSKEKAKTMYKTMWDIRNFEENTRRFFAAGQIPGFVHLYAGEEAIATGVCANLTDKDYIT 98
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ +R HG G + G+++E+ G+ TG +GKGGSMH
Sbjct: 99 STHRGHGHCVAKGGDLKGMMAEIFGKETGLGKGKGGSMH 137
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 77.0 bits (181), Expect = 4e-13
Identities = 45/100 (45%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = +1
Query: 316 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG---MRAAMRDA--DSV 480
D +L ++ RR E S Y E+ + GF HLYSGQEAVA G M A R D
Sbjct: 5 DRKRLLREMVFFRRFEDRSFEAYMERKVGGFLHLYSGQEAVATGVLEMVQADRGVGFDYA 64
Query: 481 ITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
IT YR H G V++EL G+ TG SRG+GGSMH
Sbjct: 65 ITGYRDHIHAIKAGAPAREVMAELYGKETGSSRGRGGSMH 104
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 76.6 bits (180), Expect = 5e-13
Identities = 33/100 (33%), Positives = 58/100 (58%)
Frame = +1
Query: 301 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 480
++T E L ++ ++ +R ++ L + ++G H G+EA AVG A + D D +
Sbjct: 18 SITKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVGEEAAAVGPIAGLTDEDII 77
Query: 481 ITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ +R HG G+ + G+++EL G+ TG S+G+GGSMH
Sbjct: 78 FSHHRGHGHVIAKGIDINGMMAELAGKATGTSKGRGGSMH 117
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 76.2 bits (179), Expect = 6e-13
Identities = 35/100 (35%), Positives = 58/100 (58%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
++ ++Q+ +R E + + Y++ I GF H Y GQEA+ A+ ++ T+YRCH
Sbjct: 27 IECFQQMLKIRNFELRAESAYQQGKIGGFFHAYVGQEAIQTAAVQAIGQSNWYATSYRCH 86
Query: 502 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHFL 621
L+G + +++EL GR TG ++G+GGSMHF L
Sbjct: 87 ALALLLGATPNELMAELYGRATGNAKGRGGSMHFFTDRLL 126
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 76.2 bits (179), Expect = 6e-13
Identities = 39/95 (41%), Positives = 53/95 (55%)
Frame = +1
Query: 319 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 498
A +L EQ+ +R +E +L K I+G HL GQEA+ G AA + D V + YR
Sbjct: 16 AKELLEQMIRIRLLEEKIADLRKSGEIQGSVHLCIGQEAIYSGSCAARQPGDRVFSTYRG 75
Query: 499 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHF 603
HGW + GV +L+EL R TG G+GGS +F
Sbjct: 76 HGWAHACGVPAEAILAELLARETGVCAGRGGSAYF 110
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 75.4 bits (177), Expect = 1e-12
Identities = 39/104 (37%), Positives = 56/104 (53%)
Frame = +1
Query: 289 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 468
AT L +D + + +RR ET + L+ + +I+G H GQEA+A G A +
Sbjct: 13 ATPNGLAPKDLRAALKMMLRIRRFETRAKELFLQGVIKGTAHSSVGQEAIAAGACAVLEP 72
Query: 469 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
AD ++T +R HG T G + + +EL GR TG G GGSMH
Sbjct: 73 ADFILTHHRGHGHTIAKGADLGRMFAELMGRETGYCAGLGGSMH 116
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 75.4 bits (177), Expect = 1e-12
Identities = 39/104 (37%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Frame = +1
Query: 292 TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 471
+ ++ E+ LYE + + R E LY K + GF HLY+GQEAV+ G+ ++++
Sbjct: 184 SDVNISREEICTLYEDMYLGRLFENLVAKLYYNKRVNGFVHLYNGQEAVSTGIIKNLKNS 243
Query: 472 DSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG-CSRGKGGSMH 600
D V + YR H GV +L+EL G G ++GKGGSMH
Sbjct: 244 DFVTSTYRDHVHALSKGVPAHKILNELYGNYYGSTNKGKGGSMH 287
>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
Actinomycetales|Rep: Dehydrogenase, E1 component -
Salinispora tropica CNB-440
Length = 323
Score = 74.9 bits (176), Expect = 1e-12
Identities = 38/99 (38%), Positives = 56/99 (56%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
+T +++LY + ++RR E + L + I G H Y GQE +A G+ AA+R D V
Sbjct: 1 MTEVGSVRLYRTVRLIRRFEERAIELVRSGHIVGGIHPYVGQEGIAAGVCAALRPDDVVA 60
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R HG G +++EL GR TG +RG+GGSMH
Sbjct: 61 GTHRGHGHVLAKGADPARMMAELCGRVTGLNRGRGGSMH 99
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 74.1 bits (174), Expect = 3e-12
Identities = 39/99 (39%), Positives = 55/99 (55%)
Frame = +1
Query: 310 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 489
SE +L + +R +E Y E+ +R HL GQEAVA AA+ AD ++
Sbjct: 2 SELPRRLLFDMMRIRAVEETIAKRYGEQKMRCPTHLSVGQEAVAAAAGAALEPADLAVSG 61
Query: 490 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFV 606
+R H G S+ +++E+ GR TGCSRGKGGSMH +
Sbjct: 62 HRAHAHYLAKGGSLKAMIAEIYGRVTGCSRGKGGSMHLI 100
>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
subunit; n=1; Burkholderia xenovorans LB400|Rep:
Putative 2-oxo acid dehydrogenase alpha subunit -
Burkholderia xenovorans (strain LB400)
Length = 334
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/93 (34%), Positives = 53/93 (56%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
+ +Y + ++R +E + L+ + + GF HL GQEAV+ G+ + + D++ T +R H
Sbjct: 20 IDIYRTMVLVREVELSLSRLFADSEVPGFIHLSLGQEAVSAGVASVLEVQDTLATTHRGH 79
Query: 502 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
G G+ V G E+ GR G +G+GGSMH
Sbjct: 80 GHVLARGIDVGGFFKEIMGRVGGLCKGRGGSMH 112
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 73.7 bits (173), Expect = 3e-12
Identities = 39/95 (41%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
Frame = +1
Query: 325 KLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
+L + +R IE ++Y+ E+ +R HL GQEAVAVG+ AA+R D V + +RCH
Sbjct: 5 QLLRTMVRIRCIEEEIADVYRDEQQMRTPVHLSIGQEAVAVGVCAALRTEDVVYSGHRCH 64
Query: 502 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFV 606
G + +++EL GR TGC+ G+GGS+H V
Sbjct: 65 AHYLAKGGGLGAMVAELYGRETGCAAGRGGSVHLV 99
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 73.3 bits (172), Expect = 5e-12
Identities = 42/111 (37%), Positives = 61/111 (54%), Gaps = 9/111 (8%)
Frame = +1
Query: 295 SATLTSEDALKLYEQLTILRRIETASGNLYKEKI---------IRGFCHLYSGQEAVAVG 447
+A L + D L +Y+++ I+R E + +Y E IRG HL GQEAVAVG
Sbjct: 18 NAGLKASDLLNMYKRMLIIRYFEESIRKIYHEGKNPFNMASGRIRGEMHLSIGQEAVAVG 77
Query: 448 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+RD D V++ +R H GV + G+ +E+ G+ TG +GKGG MH
Sbjct: 78 TLYDIRDEDVVVSTHRPHHHAIAKGVDLKGLAAEILGKATGLCKGKGGHMH 128
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 72.9 bits (171), Expect = 6e-12
Identities = 37/95 (38%), Positives = 51/95 (53%)
Frame = +1
Query: 316 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 495
DAL+L + +R E L+ + ++RG HL GQEAV VG+ +A+ D++ YR
Sbjct: 17 DALELLRSMYEIRFFEDEIMGLFSQNLVRGSTHLCQGQEAVTVGVCSALSPGDTMTCTYR 76
Query: 496 CHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
HG MG + E+ GR G GKGGSMH
Sbjct: 77 GHGAVLAMGAPLDRAFGEILGRAGGLCGGKGGSMH 111
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 71.7 bits (168), Expect = 1e-11
Identities = 34/88 (38%), Positives = 51/88 (57%)
Frame = +1
Query: 337 QLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYL 516
++ I+R E + L+ ++ G HL GQEAVA+G AAM+ D ++ +R HG
Sbjct: 33 RMQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASAAMKPGDYLLNHHRGHGHCLA 92
Query: 517 MGVSVLGVLSELTGRRTGCSRGKGGSMH 600
G V +++E G+ TG RG+GGSMH
Sbjct: 93 WGSDVRLMMAEFLGKETGYCRGRGGSMH 120
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 70.5 bits (165), Expect = 3e-11
Identities = 33/97 (34%), Positives = 56/97 (57%)
Frame = +1
Query: 310 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 489
++ +L+ Y ++ +R+ E + ++ + I G H Y+GQEA VG A+ D D ++
Sbjct: 6 NDRSLEKYRRMQRIRQFEDLAEAIHAQGEIPGSLHTYAGQEASGVGACMALDDTDYMVGT 65
Query: 490 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R HG G + +++EL G+ TG +GKGGSMH
Sbjct: 66 HRSHGHPIAKGAKLRPLMAELLGKATGICKGKGGSMH 102
>UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1;
Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase, E1 component -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 324
Score = 69.7 bits (163), Expect = 6e-11
Identities = 33/84 (39%), Positives = 52/84 (61%)
Frame = +1
Query: 349 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVS 528
+R IE A +L K+ +RG H Y G+EA+A G+ + + D+V + +R HG G +
Sbjct: 41 IRAIEEAIVSLAKDNKLRGPIHSYVGEEAIATGVLSHAKPIDAVTSTHRGHGHYIAKGGN 100
Query: 529 VLGVLSELTGRRTGCSRGKGGSMH 600
+ ++ EL G+ +GC+ GKGGSMH
Sbjct: 101 ISMLIDELHGKESGCNGGKGGSMH 124
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 69.7 bits (163), Expect = 6e-11
Identities = 34/99 (34%), Positives = 52/99 (52%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
L E L +Y ++ +R E + I GF HLY+G+EA VG+ + D D +
Sbjct: 14 LDKETLLTVYRKMRTIRDFEERLHVDFGRGDIPGFVHLYAGEEAAGVGILHHLNDGDRIA 73
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ +R HG GV + ++ E+ G++ G GKGGSMH
Sbjct: 74 STHRGHGHCIAKGVDPVAMMKEIYGKKGGSCNGKGGSMH 112
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 65.7 bits (153), Expect = 9e-10
Identities = 37/99 (37%), Positives = 49/99 (49%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
L+ ED K Y + + R E Y IRGF HL +GQE++ + A+R D
Sbjct: 132 LSDEDLSKAYYMMQLCRDFENECNQAYMAGKIRGFMHLDNGQESIPALLNDAIRKDDLKH 191
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ YR H GV V++EL G+ G RG GGSMH
Sbjct: 192 SYYRDHCHAIACGVDSGAVMAELFGKDGGTCRGTGGSMH 230
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 64.9 bits (151), Expect = 2e-09
Identities = 31/98 (31%), Positives = 53/98 (54%)
Frame = +1
Query: 307 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 486
++E ++ ++ ++RR E + Y +I G HL GQEA A+G+ + + D + +
Sbjct: 23 SAEQLREVLYKMYLIRRFEEGAEESYMRGLIHGTMHLSIGQEASAMGICMPLGEDDQITS 82
Query: 487 AYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R HG G V + +E G+ TG +G+GGSMH
Sbjct: 83 THRGHGHCIAKGAEVKRMFAEFFGKTTGYCKGRGGSMH 120
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 64.9 bits (151), Expect = 2e-09
Identities = 32/100 (32%), Positives = 54/100 (54%)
Frame = +1
Query: 301 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 480
+++ E L++Y+++ R+ E + ++ G HL GQEA +V A+ D V
Sbjct: 4 SISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQEASSVAAVMALEKGDLV 63
Query: 481 ITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R H MG+ + +++EL G+ TG +GKGGSMH
Sbjct: 64 SLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMH 103
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/105 (32%), Positives = 55/105 (52%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
L+ E +Y+++ +R +E +L+ + + G H GQEA AV A +++ D V
Sbjct: 14 LSQETIDSMYKKMITIRTLEETLLDLFSKGELFGTTHTSIGQEANAVASMAHIKNGDVVF 73
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
+ +RCHG G V +++E+ GR TG G+GGS H F
Sbjct: 74 SNHRCHGHYIAYGAPVDQLIAEVMGRVTGVVGGRGGSQHICYNDF 118
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 64.1 bits (149), Expect = 3e-09
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 8/118 (6%)
Frame = +1
Query: 286 PATSATLTSEDALK------LYEQLTILRRIETASGNLYKEKIIR--GFCHLYSGQEAVA 441
P T+ T EDA K ++ ++ +R E + L + R G HL +GQE V
Sbjct: 2 PGTNPRATKEDAAKAAFLSEMFGKICFVRAFEEEALRLTQANPPRVAGSMHLCAGQEVVP 61
Query: 442 VGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTH 615
V A+ D D V+ YR HGW G+ V++E+ R TG + G+ GS + + H
Sbjct: 62 VAAMEALGDEDQVVCTYRGHGWALAAGLDPEAVMAEICQRSTGLNGGRAGSAYMMAPH 119
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 63.7 bits (148), Expect = 4e-09
Identities = 38/90 (42%), Positives = 48/90 (53%)
Frame = +1
Query: 331 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWT 510
Y + + R E A+ Y + I GF HL GQEA +VG A D V T YR H
Sbjct: 10 YYLMKLGREFEIAAKQEYMKGNIAGFLHLDIGQEACSVGSMQAF-DKGDVFTHYREHVLA 68
Query: 511 YLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
G+ V++EL G+ TG S+GKGGSMH
Sbjct: 69 IARGMDPKVVMAELFGKVTGISKGKGGSMH 98
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 62.9 bits (146), Expect = 6e-09
Identities = 35/94 (37%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRG-FCHLYSGQEAVAVGMRAAMRDADSVITAYRC 498
L+LY + +R E G L+ G HL G+E+ A G+ AAM+ D+ T +R
Sbjct: 10 LELYRTMRRIRTFEERVGELFVRGQSAGSMLHLSIGEESSAAGVCAAMKPQDTFTTHHRG 69
Query: 499 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
HG G +++E+ G+ TG RGKGGSMH
Sbjct: 70 HGIFLARGADPKRMMAEIGGKETGYCRGKGGSMH 103
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 62.9 bits (146), Expect = 6e-09
Identities = 32/101 (31%), Positives = 54/101 (53%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
+ +E ++LY + +R +E YK ++ HL GQEA+A G+ +R D +
Sbjct: 1 MENERFIELYRVMQTIRIVERKIEEEYKNDEMKTPIHLSIGQEAIAAGVCINLRKDDYLF 60
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFV 606
+R H G + +++EL R+TGC+ G+GGSMH +
Sbjct: 61 GTHRSHAQYIAKGGDIKQMIAELYLRKTGCTSGRGGSMHLM 101
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
Frame = +1
Query: 307 TSEDALKLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
T E L++ + + RR E L + E + G L +GQEAVA G+ AA+ D ++
Sbjct: 4 TKEKLLEMLRSMLLTRRFEEKLTELCQIEGKVPGMMILCTGQEAVAAGVCAALEPQDVIV 63
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R HG G +++E G+RTG ++GK G++H
Sbjct: 64 PNHRSHGHLLARGADPNALMAECFGKRTGFNKGKSGTLH 102
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 61.3 bits (142), Expect = 2e-08
Identities = 37/98 (37%), Positives = 52/98 (53%)
Frame = +1
Query: 307 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 486
T+ D L+LYEQL ++R E A + I G C GQEA AVG A+ D ++T
Sbjct: 6 TAVDPLRLYEQLLLIRAYENAIVRGSTDGRIPGTCTSV-GQEAAAVGAINALEADDLILT 64
Query: 487 AYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+R G G +L+E+ GRR G +G+ GS+H
Sbjct: 65 NHRSAGHLLARGADPGRMLAEVMGRRDGYCKGRSGSLH 102
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 60.9 bits (141), Expect = 3e-08
Identities = 30/86 (34%), Positives = 48/86 (55%)
Frame = +1
Query: 343 TILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMG 522
T++R +E +LY E + G H GQE V + +A+R D +++ +R HG
Sbjct: 17 TLIRVVEERLLSLYGEGRLHGTVHTCIGQEWTGVSVASALRSGDYILSNHRGHGHYLAWT 76
Query: 523 VSVLGVLSELTGRRTGCSRGKGGSMH 600
V G+++E+ GR +G RG+GGS H
Sbjct: 77 DDVEGLIAEVMGRESGVCRGRGGSQH 102
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 60.9 bits (141), Expect = 3e-08
Identities = 30/68 (44%), Positives = 42/68 (61%)
Frame = +1
Query: 397 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCS 576
+RG HL +GQEAVA G+ + +R D + + +R HG T G + ++ EL GR +G
Sbjct: 52 VRGPLHLSTGQEAVATGVCSQLRADDWLTSTHRGHGHTIAKGADLRRMMHELFGRASGFC 111
Query: 577 RGKGGSMH 600
GKGGSMH
Sbjct: 112 GGKGGSMH 119
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 59.3 bits (137), Expect = 8e-08
Identities = 28/96 (29%), Positives = 51/96 (53%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 492
++ L++ ++ ++R E + ++ G HL GQEA+ VG+ + + D V A+
Sbjct: 26 DELLEMLSKMILIRNAEYKIAKGREFGLVGGPVHLGVGQEAIPVGISQYLNNQDKVFGAH 85
Query: 493 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
R H +G+ + SE+ + +G S+G GGSMH
Sbjct: 86 RSHSHILSLGIDLKSFFSEILAKSSGISKGMGGSMH 121
>UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1;
Thermoanaerobacter ethanolicus X514|Rep: Dehydrogenase,
E1 component - Thermoanaerobacter ethanolicus X514
Length = 262
Score = 58.0 bits (134), Expect = 2e-07
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 10/109 (9%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKI----------IRGFCHLYSGQEAVAVGMR 453
+ E +++Y ++ +R E Y+E + G HL +GQE VAVG+
Sbjct: 3 IPKETLIRMYLEMVTIRLYEETMAEAYQEGKYPVFNIASGPVPGEMHLAAGQEPVAVGVC 62
Query: 454 AAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
++ D+V+ +R H + GV + + +E+ G+ TG RGKGG MH
Sbjct: 63 MHLKKEDAVVGTHRPHHFAIAKGVDLKRMTAEIFGKVTGLGRGKGGHMH 111
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 42.3 bits (95), Expect(2) = 4e-07
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Frame = +1
Query: 307 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGF-------CHLYSGQEAVAVGMRAAMR 465
+ ED L++Y + I+R ET + G HL GQEA AVG +
Sbjct: 40 SDEDLLRIYRDMLIIREFETMLSLIKTRGEYNGIKYDYPGPAHLSIGQEAAAVGQAFILD 99
Query: 466 DADSVITAYRCHGWTYLMGVSVLGVLSE 549
D + ++R HG G+S + LSE
Sbjct: 100 KNDFIFGSHRSHGEVIAKGLSAIEKLSE 127
Score = 34.3 bits (75), Expect(2) = 4e-07
Identities = 14/22 (63%), Positives = 17/22 (77%)
Frame = +1
Query: 535 GVLSELTGRRTGCSRGKGGSMH 600
GVL+E+ GR TG +G GGSMH
Sbjct: 167 GVLAEIFGRETGFQKGLGGSMH 188
>UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12;
Bacteria|Rep: Pyruvate dehydrogenase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 344
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/102 (35%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Frame = +1
Query: 325 KLYEQLTILRRIETASGNLYK--EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 498
+ YE+ ILR G + + +I G HL +GQE VA G+ A + D+V +R
Sbjct: 37 RTYEE-AILREYHADKGPGFDIGKGLIPGEMHLSAGQEPVAAGVCAHLTTDDAVTATHRP 95
Query: 499 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFV--RTHF 618
H + GV + + +E+ GR G RG+GG MH THF
Sbjct: 96 HHFAVAHGVDLRRMTAEIFGREDGLGRGRGGHMHLFDPDTHF 137
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/102 (28%), Positives = 50/102 (49%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 492
+D +L +R++E L+ E ++ G H GQE V + A++ D+V + +
Sbjct: 11 KDCYELTVTALTIRKVEERLLELFSEGVLNGTIHTCIGQEWTGVAVANALQAGDTVFSNH 70
Query: 493 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
R HG + V G+++E+ G+ G G GGS H +F
Sbjct: 71 RGHGHYIALTGDVYGLIAEIMGKDDGVCGGVGGSQHLHTENF 112
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 55.6 bits (128), Expect = 1e-06
Identities = 28/68 (41%), Positives = 38/68 (55%)
Frame = +1
Query: 397 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCS 576
I G HL +G EA G+ +RD D+V +R H GV + + +E+ GR+TG
Sbjct: 43 IPGELHLAAGHEASGAGVCMHLRDDDTVTAPHRPHHIAIAKGVDLKRMTAEIFGRKTGLC 102
Query: 577 RGKGGSMH 600
RGKGG MH
Sbjct: 103 RGKGGHMH 110
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/95 (30%), Positives = 47/95 (49%)
Frame = +1
Query: 325 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 504
+LYE +T+++ + ++ GQEA+A M +R D ++T YR
Sbjct: 16 RLYELMTLMKAADDRLSRGIASGELQCVYWPPRGQEAIAAAMGVCLRSDDQLVTTYRGLH 75
Query: 505 WTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHFVR 609
GV ++ + E+ GR+ G RGKGG+MH R
Sbjct: 76 DLIGKGVPLVEIYGEMLGRQVGSGRGKGGTMHIAR 110
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 54.8 bits (126), Expect = 2e-06
Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 3/110 (2%)
Frame = +1
Query: 280 QGPATSATLTSE---DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 450
Q PA AT+T D L Y + + R E G ++ + G+ H G EA
Sbjct: 13 QNPAADATVTERSDADLLSTYRLMVLAREFEEQLGAIFAAGKLGGWFHSCIGHEATGAAA 72
Query: 451 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
A MR+ D ++ +R G++ + E+ GR T SRG+ G H
Sbjct: 73 AALMRETDHLVPYHRSRVSILGKGMTARDLAMEIMGRATAPSRGRAGETH 122
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 53.2 bits (122), Expect = 5e-06
Identities = 28/91 (30%), Positives = 43/91 (47%)
Frame = +1
Query: 346 ILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGV 525
++R E A LY + G H GQE + ++ D V + +RCHG
Sbjct: 11 LIRETEEALLRLYSTGELHGTVHTCIGQELTGAIVCKFLKKNDWVFSNHRCHGHFLSRTG 70
Query: 526 SVLGVLSELTGRRTGCSRGKGGSMHFVRTHF 618
V G+++E+ G+ TG G+GGS H + F
Sbjct: 71 DVTGLIAEVMGKETGVCGGRGGSQHLCKEGF 101
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 1/105 (0%)
Frame = +1
Query: 289 ATSATLTSEDALKLYEQLTILRRIETA-SGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 465
+ + +L +E A K + ++R +E LY++ I G ++ GQEA+ VG
Sbjct: 16 SAAGSLQAELAHKCLYYMLLMREVEDRIERKLYRQGKILGGVYVGRGQEAIPVGSALVAV 75
Query: 466 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
D + ++R ++ GVS VL++ GR G +RG+ G+MH
Sbjct: 76 PEDVMFPSHRDMAVFFIRGVSARRVLAQYMGRLGGLTRGRDGNMH 120
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/90 (31%), Positives = 44/90 (48%)
Frame = +1
Query: 328 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 507
++ +L + R +ET +E+ G+ H GQEA +G AA+ D V R W
Sbjct: 12 MFHKLAVSRAVETLMLRHTREERFSGWWHPGEGQEAAPIGATAALEADDYVWYQGRGCAW 71
Query: 508 TYLMGVSVLGVLSELTGRRTGCSRGKGGSM 597
G+ L +L +L G+ G + GKGG +
Sbjct: 72 AIGKGMDPLPILGDLLGKTNGATGGKGGGV 101
>UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha
subunit; n=2; Bacteria|Rep: Putative pyruvate
dehydrogenase alpha subunit - Streptomyces coelicolor
Length = 323
Score = 50.0 bits (114), Expect = 5e-05
Identities = 28/94 (29%), Positives = 43/94 (45%)
Frame = +1
Query: 340 LTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLM 519
L ++R E A L+ + + G H GQE + V + + + D V + +R HG
Sbjct: 38 LLMIRHFELAVLELFSQGRLHGTTHTCLGQEYIPVALYPLLDEGDYVFSNHRGHGHYLAR 97
Query: 520 GVSVLGVLSELTGRRTGCSRGKGGSMHFVRTHFL 621
G+L+E+ GR G GGS H R +L
Sbjct: 98 FHDPHGLLAEIMGRAGAVCHGVGGSQHIYRDRYL 131
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 49.2 bits (112), Expect = 8e-05
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 328 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 507
LY+ L I R IE Y + +R HL GQEA+ + + + + D +++ +R H
Sbjct: 11 LYKLLRI-RMIEEEIVLQYPKGKMRCPTHLSIGQEAIPIMVCENLHNTDLMVSTHRAHAH 69
Query: 508 TYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
G ++ +++EL G+ TG + G+GGSM+
Sbjct: 70 YLAKGGNLKALIAELHGKVTGATAGRGGSMN 100
>UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 58
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/54 (40%), Positives = 35/54 (64%)
Frame = +1
Query: 301 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 462
T+ ++ LK Y+ ++ R+ E +LY ++ IRGF HLY+GQEA+ G+ AM
Sbjct: 3 TINNDIYLKWYKDMSFWRKFEDKCRSLYLKQKIRGFLHLYNGQEAIPAGLVHAM 56
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/85 (31%), Positives = 45/85 (52%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
++ E LYE + ++RRI+T + L ++ + G GQEA +G ++RD D V
Sbjct: 53 VSDEQLGSLYEDMVVIRRIDTEATALQRQGEL-GLWPPLLGQEASQIGSARSLRDDDFVF 111
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTG 558
++YR +G Y GV + +L G
Sbjct: 112 SSYRENGVAYCRGVDLADILKVWRG 136
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/106 (27%), Positives = 49/106 (46%)
Frame = +1
Query: 283 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 462
G TL + L+LY + + R ++ L ++ I GF G+EA +G AAM
Sbjct: 44 GAPDEVTLPDAEVLRLYRLMVLNRSLDERMITLQRQGRI-GFYIGSIGEEATILGSAAAM 102
Query: 463 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
++D + YR HG + G+ ++ L +L G +G+ H
Sbjct: 103 AESDWIFPCYREHGAALMRGMPLVTFLCDLFGNAGDAMKGRQMPCH 148
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 46.4 bits (105), Expect = 6e-04
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 21/116 (18%)
Frame = +1
Query: 316 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 495
D LK Y Q+ ++RR E + K ++ G H GQEA AVG + ++ D + +R
Sbjct: 30 DLLKWYSQMKLIRRFEEKILDFEKAGLVHGPAHASIGQEAAAVGAMSVLKTDDQINGTHR 89
Query: 496 CH---------------------GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
H +T M +V +++E+ G TG G+GGSMH
Sbjct: 90 THHQVLTKLINAQTPSDFDILQSDFTDGMHDAVYRLMAEIMGLNTGYCGGRGGSMH 145
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 46.4 bits (105), Expect = 6e-04
Identities = 28/91 (30%), Positives = 41/91 (45%)
Frame = +1
Query: 298 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 477
A +T E+ LY + + RR + + +L ++ + G GQEA +G A RD D
Sbjct: 63 ADITPEELRGLYRDMVLSRRFDAEATSLQRQGEL-GLWASMLGQEAAQIGSGRATRDDDY 121
Query: 478 VITAYRCHGWTYLMGVSVLGVLSELTGRRTG 570
V YR HG + GV +L G G
Sbjct: 122 VFPTYREHGVAWCRGVDPTNLLGMFRGVNNG 152
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 46.4 bits (105), Expect = 6e-04
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 10/102 (9%)
Frame = +1
Query: 325 KLYEQLTILRRIE----TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI--- 483
+L + T + RI T + + + RG+ H Y+GQEAVAVG+ +A+R++ V+
Sbjct: 30 QLVDMFTTILRIRWHERTMADKMLTDPNYRGYNHFYAGQEAVAVGVCSALRNSGGVMHAD 89
Query: 484 TAYRCH---GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
AY H G GV + + +E R TG + G MH
Sbjct: 90 LAYSTHRPTGHAIAKGVDMKLMAAENDFRATGLNGGYAAEMH 131
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 46.0 bits (104), Expect = 8e-04
Identities = 28/96 (29%), Positives = 43/96 (44%)
Frame = +1
Query: 271 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 450
+L P L +D +K E + + RR++ + L + + G GQEA G
Sbjct: 40 RLTTHPDFPVDLVDDDLVKALEMMVMTRRLDVEATALQRHGEL-GLWPPLLGQEATQAGA 98
Query: 451 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 558
A+R+ D V YR G + MGVS+ +L G
Sbjct: 99 WLALREGDQVFPTYREQGLAHAMGVSLADILGAWDG 134
>UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7;
Mycobacterium tuberculosis complex|Rep: Dehydrogenase E1
component - Mycobacterium tuberculosis (strain ATCC
25177 / H37Ra)
Length = 334
Score = 46.0 bits (104), Expect = 8e-04
Identities = 28/92 (30%), Positives = 45/92 (48%)
Frame = +1
Query: 325 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 504
+LY ++ +LR ++ A L E +I G GQEAV+VG AA+ + D +IT +R H
Sbjct: 18 ELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAAAALGEGDVIITTHRPHA 77
Query: 505 WTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
+ V++++ G G G H
Sbjct: 78 QHVGTDAPLGPVIADMLGATAGDLEGADEDAH 109
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/95 (28%), Positives = 47/95 (49%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
+T + A + Y + +R + + +L ++ I + + GQEA VG AA+++ D +
Sbjct: 35 ITEQLAKEFYRHMVRIRTFDKKAISLQRQGRIGTYAP-FEGQEASQVGSSAALKEDDWMF 93
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKG 588
+YR HG G S+ +L GR GC +G
Sbjct: 94 PSYRDHGAAMTFGHSLRNILLFWKGRNEGCVPPQG 128
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
Frame = +1
Query: 310 SEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR-DADSVI 483
S D LK +Y ++ LR + NL ++ + F +SGQEA VG +R D D +
Sbjct: 35 SVDQLKDVYRKMVYLRVFDQRCLNLQRQGRMGTFAP-FSGQEASQVGSAYLLRPDRDWIF 93
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKG 588
YR HG ++MGV ++ +L G G +G
Sbjct: 94 PTYRDHGAMHVMGVPLVNILRYFMGDEQGSHAPQG 128
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/93 (31%), Positives = 41/93 (44%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
L L+ T + R + +L I G + GQE A + A +R D V+T YR
Sbjct: 25 LGLFRTATRIARFDEKYRSLMTSGAIGGMYYSPRGQEFAAASVAAHLRRDDYVVTTYRGL 84
Query: 502 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
GV + + +E G+ G GKGG MH
Sbjct: 85 HDQIAKGVPLRELWAEYLGKAAGTCGGKGGPMH 117
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 44.4 bits (100), Expect = 0.002
Identities = 29/91 (31%), Positives = 40/91 (43%)
Frame = +1
Query: 286 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 465
P L E+ L L + +LRR++ A G + + G GQEA VG A R
Sbjct: 36 PEHEVDLEPEELLALLRDMVLLRRLD-AEGEALQRQGQLGLWPGSRGQEAAQVGSATACR 94
Query: 466 DADSVITAYRCHGWTYLMGVSVLGVLSELTG 558
D V +YR HG G+ + +LS G
Sbjct: 95 RQDQVFPSYRDHGAVLGRGIDPVDILSIFRG 125
>UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG1071:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Magnetospirillum magnetotacticum MS-1
Length = 311
Score = 44.0 bits (99), Expect = 0.003
Identities = 29/91 (31%), Positives = 43/91 (47%)
Frame = +1
Query: 328 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 507
L Q+ +R + K K R HL G EA+AV + AAM + DS+ +R +
Sbjct: 12 LARQVLRVRLAQMLINEALKAKKFRVPVHLALGHEAIAVAVGAAMAEGDSLFLTHRNIHY 71
Query: 508 TYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
S+ +SEL R G + G+ GSM+
Sbjct: 72 NIARATSLAAEVSELALRPDGLAGGRLGSMN 102
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 43.2 bits (97), Expect = 0.006
Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 21/113 (18%)
Frame = +1
Query: 325 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH- 501
++ EQL ++R E L KE ++ G H GQE AVG+ +A+ D + +R H
Sbjct: 47 RMLEQLFLIRHFEERLLELSKEGLLHGPAHASIGQEGAAVGLMSALTSGDKINGTHRMHH 106
Query: 502 --------------------GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
G+ V SE+ G ++G G+GGSMH
Sbjct: 107 QFLAKTLNHALVAEYDPLDQGFPQAAQEVVFKTYSEILGLKSGYCGGRGGSMH 159
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 41.1 bits (92), Expect = 0.022
Identities = 23/89 (25%), Positives = 45/89 (50%)
Frame = +1
Query: 304 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 483
LT ++ +++Y + + RR + + +L ++ I + L SGQE + A+ D D ++
Sbjct: 79 LTDDELVEMYRYMKLARRFDERAVSLQRQGRIGTYPPL-SGQEGAQIASAMALADDDWIV 137
Query: 484 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 570
+YR HG + + G+ + L G G
Sbjct: 138 PSYREHGASLVRGLPLKDTLLYWMGDERG 166
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 40.3 bits (90), Expect = 0.039
Identities = 21/59 (35%), Positives = 29/59 (49%)
Frame = +1
Query: 424 GQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
GQE + + ++ D D V T YR G + +E+ GR TG +GKGG MH
Sbjct: 47 GQEIIPAAISVSLTDDDYVNTIYRGGHDQIAKGFPLPDYWAEIAGRVTGACKGKGGPMH 105
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 39.9 bits (89), Expect = 0.052
Identities = 24/70 (34%), Positives = 36/70 (51%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
L LY + + R +T + L + + F GQEA+ VG+ +AMR D + +YR H
Sbjct: 36 LALYRAMVLTRAFDTKAIALQRTGKLGTFASSV-GQEAIGVGVASAMRAEDVLFPSYRDH 94
Query: 502 GWTYLMGVSV 531
L GVS+
Sbjct: 95 SAQLLRGVSM 104
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 38.7 bits (86), Expect = 0.12
Identities = 24/83 (28%), Positives = 42/83 (50%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
L LY ++ ++R+++ + NL + + G GQEAV +GM +AM+ D YR
Sbjct: 39 LYLYRRMALIRQLDNKAINLQRTGKM-GTYPSSRGQEAVGIGMGSAMQKEDIFCPYYRDQ 97
Query: 502 GWTYLMGVSVLGVLSELTGRRTG 570
G + G+ + +L+ G G
Sbjct: 98 GALFEHGIKLSEILAYWGGDERG 120
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 38.7 bits (86), Expect = 0.12
Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 492
E L YE++ E E I GF H GQE VG AA+ D ++ A+
Sbjct: 10 ERLLDFYERMVRCMLWEQKLLRFIDEGKISGFYHAGRGQEGTQVGAVAALGPDDYMMYAH 69
Query: 493 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKG-GSMH 600
R G+ G+ + + + G +RG G G +H
Sbjct: 70 RGCGYMVARGMPMSKLFGDFLANTEGSTRGLGAGIVH 106
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 38.3 bits (85), Expect = 0.16
Identities = 25/82 (30%), Positives = 42/82 (51%)
Frame = +1
Query: 250 IKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQ 429
+KP + LD+G L E+AL+LY + R + + L ++ + G + GQ
Sbjct: 1 MKPKVVRYLDEG---EFPLAEEEALRLYRAMRRARFFDEKALTLQRQGRL-GVYAPFMGQ 56
Query: 430 EAVAVGMRAAMRDADSVITAYR 495
EA VG+ A+ + D V+ +YR
Sbjct: 57 EAAQVGVALALEERDWVVPSYR 78
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 38.3 bits (85), Expect = 0.16
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
L LY + + R+ + + + + I F GQEA+ VG+ AMR D ++ +YR H
Sbjct: 36 LPLYRAMVLTRQFDLKAIAMQRTGQIGTFASAL-GQEAIGVGVATAMRRDDVLVPSYRDH 94
Query: 502 GWTYLMGVSV 531
++ GV++
Sbjct: 95 AAQFVRGVTM 104
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 37.9 bits (84), Expect = 0.21
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 20/111 (18%)
Frame = +1
Query: 328 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH-- 501
+ Q+ ++R E L + ++ G H GQE AVG +MR +D + ++R H
Sbjct: 34 MLSQMHLIRAFEEKVLELAGQGLVHGPAHSAIGQEGGAVGSAVSMRPSDQINGSHRAHHQ 93
Query: 502 ------GWTYLMGVS------------VLGVLSELTGRRTGCSRGKGGSMH 600
G+ G+ L+E+ G G RG+GGSMH
Sbjct: 94 FLAKALGYVAQKGIDPKAAFDQDIRTLAQRTLAEILGLSQGFCRGRGGSMH 144
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 37.9 bits (84), Expect = 0.21
Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 3/112 (2%)
Frame = +1
Query: 274 LDQGPATSATLTSEDALKL---YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 444
L + P SA DA KL Y + +RR + + L ++ + + L +GQEA +
Sbjct: 45 LGEDPVFSAYANRLDAEKLRGFYADMAAIRRFDQEATALQRQGQLALWVPL-TGQEAAQI 103
Query: 445 GMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 600
G A + D + YR HG V + +L + G G K + H
Sbjct: 104 GSGRASQPQDYIFPTYREHGVALTRNVDLAELLRQFRGVSNGGWNPKDTNFH 155
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 37.5 bits (83), Expect = 0.28
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = +1
Query: 271 KLDQGPATSATLTSEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 447
+L P + S+ AL LY Q+ ++RR E +L ++ + + +GQEA VG
Sbjct: 26 RLTDTPTEGLRIPSDAALTGLYRQMVLVRRFEAQVTHLTRQGRLATYPSA-AGQEAAEVG 84
Query: 448 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 558
A+ D + YR GV V +L+ G
Sbjct: 85 ATTALAPNDWLFPTYRDSAALLTRGVPVAEILAAFRG 121
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 37.1 bits (82), Expect = 0.37
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 286 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 465
P L+ + LK+Y+ + + R+ + A+ Y+ + G L SGQEA VG+ AA+
Sbjct: 26 PELEPKLSKDVLLKMYKTMVLGRQADLAALK-YQRQGRMGNYLLNSGQEASQVGVAAALE 84
Query: 466 DADSVITAYRCHGWTYLMGVSV 531
D V YR G GVS+
Sbjct: 85 PQDWVSPYYRDAGIFLYRGVSL 106
>UniRef50_A2C5U8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=1; Prochlorococcus marinus str. MIT
9303|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Prochlorococcus marinus (strain MIT 9303)
Length = 280
Score = 37.1 bits (82), Expect = 0.37
Identities = 22/84 (26%), Positives = 38/84 (45%)
Frame = +1
Query: 349 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVS 528
+R + A + Y + +R HL GQE ++ + D +++R H +
Sbjct: 1 MRAFQLAIADEYHNQKMRCPVHLSIGQEYWLPLVKKFFQKTDRCFSSHRSHSMYLALACD 60
Query: 529 VLGVLSELTGRRTGCSRGKGGSMH 600
+++EL G G +G GGSMH
Sbjct: 61 PESLIAELHGSAFGSLQGLGGSMH 84
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 36.3 bits (80), Expect = 0.64
Identities = 23/79 (29%), Positives = 39/79 (49%)
Frame = +1
Query: 322 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 501
++ Y + + RR++ + L ++ + + L GQEA VG AA R D + +YR H
Sbjct: 76 MEFYTSMVLARRLDEEATALQRQGELVLWIPL-RGQEAAQVGSAAAARPRDYLFPSYREH 134
Query: 502 GWTYLMGVSVLGVLSELTG 558
+ GV + V+ L G
Sbjct: 135 AVAWHRGVPAVEVIRLLRG 153
>UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily
protein; n=2; Mycobacterium avium|Rep: Dehydrogenase E1
component superfamily protein - Mycobacterium avium
(strain 104)
Length = 297
Score = 36.3 bits (80), Expect = 0.64
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Frame = +1
Query: 313 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV--IT 486
+D L+ Y ++ +LR ++ A I + GQEAVAVG AA+R D V T
Sbjct: 7 DDRLEPYRRMWVLRLLDMALDESAVGAAIDDDAPVDFGQEAVAVGAVAALRPGDLVNATT 66
Query: 487 AYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 594
H +G+ + ++EL G G G GGS
Sbjct: 67 PRFRHAQQIGLGLPLGPAIAELLGTTRG---GAGGS 99
>UniRef50_UPI00004D6EAE Cluster: Ras and Rab interactor 1 (Ras
interaction/interference protein 1) (Ras inhibitor
JC99).; n=2; Xenopus tropicalis|Rep: Ras and Rab
interactor 1 (Ras interaction/interference protein 1)
(Ras inhibitor JC99). - Xenopus tropicalis
Length = 752
Score = 35.9 bits (79), Expect = 0.84
Identities = 26/95 (27%), Positives = 42/95 (44%)
Frame = +1
Query: 184 KVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIE 363
KV P+ T ++ ++ + P ++ D G ++S TSED K QLT R+I+
Sbjct: 308 KVPVPLTRTQESKEIEQSSSNGLSPVEVQ--DSGSSSSEEGTSEDFGKFSPQLTRRRKIK 365
Query: 364 TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 468
SG + F L S + V + + RD
Sbjct: 366 KKSGRSSFRAVSGAFLSLLSPERKVLMFIEEMSRD 400
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 35.9 bits (79), Expect = 0.84
Identities = 25/82 (30%), Positives = 38/82 (46%)
Frame = +1
Query: 325 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 504
+ Y QL +R + + NL ++ I G + GQE VG A+ + D ++ YR H
Sbjct: 37 QFYRQLICMRAFDQKAINLQRQGRI-GTYPGFEGQEGAQVGSALALDEDDWMLPTYRDHA 95
Query: 505 WTYLMGVSVLGVLSELTGRRTG 570
+ G S +LS GR G
Sbjct: 96 ASITFGKSYT-ILSSWNGRVEG 116
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 35.5 bits (78), Expect = 1.1
Identities = 20/86 (23%), Positives = 41/86 (47%)
Frame = +1
Query: 301 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 480
+L ED + Y + ++R+I+ + L + + + +Y GQEA +G A + D +
Sbjct: 33 SLDVEDIQRFYRDIILVRQIDHEAALLQRRGELALWPPVY-GQEASQIGATYACSENDMI 91
Query: 481 ITAYRCHGWTYLMGVSVLGVLSELTG 558
+YR H + G+ ++ + G
Sbjct: 92 FPSYRDHAVMHARGIDLVHIAKLFRG 117
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 35.5 bits (78), Expect = 1.1
Identities = 23/72 (31%), Positives = 34/72 (47%)
Frame = +1
Query: 289 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 468
AT L+ E +Y L RR + + +L ++ I + +GQE AVG A+ D
Sbjct: 35 ATVPDLSDERFRAIYRDLVTTRRFDERAVSLQRQGRIGTYAPC-AGQEGSAVGSTHALAD 93
Query: 469 ADSVITAYRCHG 504
D + YR HG
Sbjct: 94 RDLISYQYREHG 105
>UniRef50_Q0AAD2 Cluster: Riboflavin biosynthesis protein RibF; n=3;
Gammaproteobacteria|Rep: Riboflavin biosynthesis protein
RibF - Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 322
Score = 34.3 bits (75), Expect = 2.6
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Frame = +1
Query: 301 TLTSEDALKLYEQLTILR-RIETASGNLYKEKIIRGFCHLYSGQ--EAVAVGMRAAMRDA 471
TL +ED E+++ R R A+G+L + + + G + SG+ A+G R R A
Sbjct: 155 TLATEDG----ERISSTRVRAALAAGDLGEAEDLLGRPYTLSGRVVRGDAIGRRLGFRTA 210
Query: 472 DSVITAYRCHGWTYLMGVSVLGVLSE-LTG-RRTGCSRGKGGSMHFVRTHFLRWQ 630
+ A + + VSV GV L G G GG H + H L WQ
Sbjct: 211 NIAFRANQRPALGGIFTVSVEGVADRPLPGVANVGTRPAVGGKRHLLEVHLLDWQ 265
>UniRef50_A3DC57 Cluster: Methyl-accepting chemotaxis sensory
transducer; n=1; Clostridium thermocellum ATCC
27405|Rep: Methyl-accepting chemotaxis sensory
transducer - Clostridium thermocellum (strain ATCC 27405
/ DSM 1237)
Length = 600
Score = 34.3 bits (75), Expect = 2.6
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 3/102 (2%)
Frame = +1
Query: 172 NTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTIL 351
NT+ V APV+ E +K +K D +A + D L Y +
Sbjct: 198 NTLDAVNAPVLEIQEVLKKVSEGHLNVKVKGDYKGDYAELKNALNNTIDTLHSYIEEISR 257
Query: 352 RRIETASGNL---YKEKIIRGFCHLYSGQEAVAVGMRAAMRD 468
E A GNL EK + F H++ + + V + +R+
Sbjct: 258 VLTEMAKGNLDVSLSEKYLGDFAHIHEALDTIIVSLNGMIRE 299
>UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginalis
G3|Rep: DnaK protein - Trichomonas vaginalis G3
Length = 726
Score = 33.9 bits (74), Expect = 3.4
Identities = 23/63 (36%), Positives = 34/63 (53%)
Frame = +1
Query: 124 DKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSAT 303
D K + +A K LAG +TK+ A + +Y+ K TF KP + +D G A+S T
Sbjct: 161 DSQKKKVSAAIK-LAGLKLTKIIDEKTALSLQYAIDKHDTFVSKPKYVAIIDFG-ASSLT 218
Query: 304 LTS 312
L+S
Sbjct: 219 LSS 221
>UniRef50_Q9Y149 Cluster: Mediator of RNA polymerase II
transcription subunit 15; n=1; Drosophila
melanogaster|Rep: Mediator of RNA polymerase II
transcription subunit 15 - Drosophila melanogaster
(Fruit fly)
Length = 749
Score = 33.9 bits (74), Expect = 3.4
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = -1
Query: 594 GTSLAPGAAGPAPRQLREHPQHTNAHEISPSVTTIR 487
G + APGA GP P Q++ P + NA + P + I+
Sbjct: 235 GPNAAPGAGGPGPNQMQGGPMNVNAMQQMPPMQQIQ 270
>UniRef50_UPI0000F2D933 Cluster: PREDICTED: similar to doublecortin
domain containing 5; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to doublecortin domain containing 5 -
Monodelphis domestica
Length = 745
Score = 33.5 bits (73), Expect = 4.5
Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Frame = +1
Query: 82 KDH*IN-LGFIEIIIDKMSKLIP--SAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEI 252
KD IN +G+ + + +K++ + AK L G K P + +K++ F +
Sbjct: 240 KDEEINQVGYYFRLPGRKTKIMVCLACAKSLIGQKEVKKLPPTSKFLCAFGSKEQKQFSL 299
Query: 253 KPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNL 381
K + ++QG AT +EDA++ YE L + + +T++ L
Sbjct: 300 KYLNVIGMNQGDL--ATYEAEDAIRHYEDLLLAFQKKTSTHTL 340
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 33.5 bits (73), Expect = 4.5
Identities = 24/91 (26%), Positives = 39/91 (42%)
Frame = +1
Query: 286 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 465
P + S Y ++ RR++ + L ++ + + L GQEA VG AA
Sbjct: 31 PRFTVRADSRQTESFYREMVRARRLDEEATALQRQGELVLWIPL-RGQEAAQVGSAAAAE 89
Query: 466 DADSVITAYRCHGWTYLMGVSVLGVLSELTG 558
AD + +YR H + G+ + L L G
Sbjct: 90 PADFLFPSYREHAVVWHRGIPPVEALRLLRG 120
>UniRef50_A0TJ86 Cluster: Putative uncharacterized protein; n=1;
Burkholderia ambifaria MC40-6|Rep: Putative
uncharacterized protein - Burkholderia ambifaria MC40-6
Length = 613
Score = 33.5 bits (73), Expect = 4.5
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 2/65 (3%)
Frame = -1
Query: 645 APTIPLPP*KVRPYKMHGTSLAPGAAGPAPRQLREHPQHTNAHEISPS--VTTIRGDHRV 472
A T P PP + R + G+S P A PAPR +R + S T R D R
Sbjct: 365 AATSPCPPARRRSPRSRGSSNPPSRAAPAPRGIRAAASRAPRSRAARSRRAATARADPRA 424
Query: 471 CIAHR 457
A+R
Sbjct: 425 PAANR 429
>UniRef50_A7S2A1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1324
Score = 33.5 bits (73), Expect = 4.5
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = -2
Query: 578 REQPVLRPVSSESTPSTLTPMR*VHP*QR-YAVITESASRIAALIPTATASCPEYR*QKP 402
+EQ + R +S + + + PMR HP Q Y TE S A P S +YR Q+P
Sbjct: 895 KEQEICRGLSHCISIADIQPMRQTHPRQNPYMYTTELTSSFAKDSPNVRDSLVQYR-QQP 953
Query: 401 RMIFSLYRFPDAVSILRNIVSCS 333
+ PD + + ++C+
Sbjct: 954 QQRTRPASLPDQSELSKQGLACT 976
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 33.5 bits (73), Expect = 4.5
Identities = 23/85 (27%), Positives = 38/85 (44%)
Frame = +1
Query: 241 TFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 420
TF + + H + G + AT E L +Y +T++ ++ ++ I F
Sbjct: 111 TFRVLDEEGHMVKDGHESQAT--KEQTLSIYRTMTLIPIVDNVLYQSQRQGRI-SFYMQC 167
Query: 421 SGQEAVAVGMRAAMRDADSVITAYR 495
+G+EA VG AAM D + YR
Sbjct: 168 AGEEAAIVGSAAAMLANDEIFGQYR 192
>UniRef50_A1D894 Cluster: Mating-type protein, putative; n=1;
Neosartorya fischeri NRRL 181|Rep: Mating-type protein,
putative - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 243
Score = 33.5 bits (73), Expect = 4.5
Identities = 16/28 (57%), Positives = 17/28 (60%)
Frame = -2
Query: 608 RTKCMEPPLPREQPVLRPVSSESTPSTL 525
R C+ P L RE VL PVSS TPS L
Sbjct: 113 RNLCLSPSLLRESVVLHPVSSPRTPSPL 140
>UniRef50_Q5WCD3 Cluster: Putative uncharacterized protein; n=1;
Bacillus clausii KSM-K16|Rep: Putative uncharacterized
protein - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 33.1 bits (72), Expect = 6.0
Identities = 12/25 (48%), Positives = 15/25 (60%)
Frame = +1
Query: 568 GCSRGKGGSMHFVRTHFLRWQRDCW 642
G S GK G H V+ + RW+R CW
Sbjct: 236 GLSMGKAGMFHDVKANVTRWKRLCW 260
>UniRef50_Q6QXE3 Cluster: ORF24; n=1; Agrotis segetum
granulovirus|Rep: ORF24 - Agrotis segetum granulosis
virus (AsGV) (Agrotis segetumgranulovirus)
Length = 362
Score = 32.7 bits (71), Expect = 7.9
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Frame = +1
Query: 214 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDAL--KLYEQLTILRRIETASGNLYK 387
+K K F I+ +++LD+ A A LT L + EQ+T +RRI+ N+
Sbjct: 169 SKKPNKAPVRFYIEDL-INRLDEIIAEPAMLTENIRLIKEKVEQMTTIRRIQ----NIAP 223
Query: 388 EKIIRGFCHLYSGQEAV 438
+K ++ + H+Y G+E +
Sbjct: 224 KKELKSYVHIYVGREVI 240
>UniRef50_A2DM79 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1353
Score = 32.7 bits (71), Expect = 7.9
Identities = 19/57 (33%), Positives = 28/57 (49%)
Frame = +1
Query: 217 KYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYK 387
+Y+T+K A+F ++ +L KLDQ PA E Y QL L + N Y+
Sbjct: 129 EYNTRKSASFPVRSEELKKLDQPPAIETEFPYEIE---YFQLHYLPAVNILLSNFYE 182
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 631,074,230
Number of Sequences: 1657284
Number of extensions: 12125682
Number of successful extensions: 38659
Number of sequences better than 10.0: 124
Number of HSP's better than 10.0 without gapping: 36976
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38615
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48955894634
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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