Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30450
(703 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 218 1e-55
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 213 3e-54
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 206 4e-52
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 206 5e-52
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 186 6e-46
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 184 2e-45
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 179 7e-44
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 178 1e-43
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 177 2e-43
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 175 9e-43
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 172 6e-42
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 171 1e-41
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 171 1e-41
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 171 2e-41
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 170 2e-41
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 170 3e-41
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 170 3e-41
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 169 6e-41
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 169 8e-41
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 166 4e-40
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 165 1e-39
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 164 2e-39
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 163 3e-39
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 162 7e-39
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 162 7e-39
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 162 9e-39
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 161 1e-38
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 161 2e-38
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 159 5e-38
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 158 1e-37
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 158 1e-37
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 158 1e-37
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 158 1e-37
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 157 2e-37
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 157 2e-37
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 157 2e-37
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 157 2e-37
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 157 3e-37
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 157 3e-37
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 155 1e-36
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 154 2e-36
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 153 3e-36
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 150 4e-35
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 150 4e-35
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 146 5e-34
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 145 8e-34
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 144 2e-33
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 143 3e-33
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 143 4e-33
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 141 2e-32
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 141 2e-32
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 138 9e-32
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 136 6e-31
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 132 8e-30
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 130 2e-29
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 129 6e-29
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 128 2e-28
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 127 2e-28
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 125 1e-27
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 125 1e-27
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 123 5e-27
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 122 6e-27
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 122 6e-27
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 122 9e-27
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 122 1e-26
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 121 2e-26
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 119 6e-26
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 118 1e-25
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 118 1e-25
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 117 2e-25
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 116 4e-25
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 116 4e-25
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 116 6e-25
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 116 6e-25
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 116 7e-25
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 116 7e-25
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 114 2e-24
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 113 3e-24
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 113 3e-24
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-24
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 112 7e-24
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 111 1e-23
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 1e-23
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 111 2e-23
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 111 2e-23
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 111 2e-23
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 2e-23
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 111 2e-23
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 110 4e-23
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 110 4e-23
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 109 6e-23
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 6e-23
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 109 9e-23
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 109 9e-23
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 109 9e-23
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 9e-23
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 108 1e-22
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 108 1e-22
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 2e-22
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 107 2e-22
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 107 3e-22
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 106 6e-22
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 106 6e-22
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 105 8e-22
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 105 1e-21
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 104 2e-21
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 104 2e-21
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 104 2e-21
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 104 2e-21
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 4e-21
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 103 4e-21
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 4e-21
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 4e-21
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 103 6e-21
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 103 6e-21
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 6e-21
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 103 6e-21
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 102 7e-21
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 102 7e-21
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 101 1e-20
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 101 2e-20
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 100 3e-20
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 99 5e-20
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 99 5e-20
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 99 5e-20
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 100 7e-20
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 100 7e-20
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 100 7e-20
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 99 9e-20
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 1e-19
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 98 2e-19
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 98 2e-19
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 2e-19
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 98 2e-19
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 3e-19
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 97 3e-19
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 4e-19
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 4e-19
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 97 4e-19
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 5e-19
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 97 5e-19
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 97 5e-19
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 96 6e-19
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 96 6e-19
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 96 6e-19
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 96 8e-19
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 95 1e-18
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 95 1e-18
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 95 2e-18
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 94 3e-18
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 94 3e-18
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 94 3e-18
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 94 3e-18
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 94 3e-18
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 94 3e-18
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 93 5e-18
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 93 5e-18
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 93 5e-18
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 5e-18
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 93 5e-18
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 93 6e-18
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 8e-18
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 93 8e-18
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 92 1e-17
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 92 1e-17
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 92 1e-17
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 92 1e-17
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 91 2e-17
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 91 2e-17
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 91 2e-17
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 91 2e-17
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 91 3e-17
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 3e-17
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 3e-17
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 91 3e-17
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 90 4e-17
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 90 4e-17
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 90 6e-17
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 90 6e-17
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 89 7e-17
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 89 1e-16
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 89 1e-16
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 89 1e-16
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 89 1e-16
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 89 1e-16
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 89 1e-16
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 2e-16
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 88 2e-16
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 88 2e-16
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 87 3e-16
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 87 3e-16
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 87 3e-16
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 87 4e-16
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 87 4e-16
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 87 4e-16
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 87 4e-16
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 5e-16
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 87 5e-16
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 86 7e-16
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 9e-16
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 9e-16
UniRef50_A0AFI6 Cluster: Complete genome; n=1; Listeria welshime... 86 9e-16
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 86 9e-16
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 85 1e-15
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 85 1e-15
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 85 1e-15
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 85 2e-15
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 85 2e-15
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 85 2e-15
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 85 2e-15
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 3e-15
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 3e-15
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 4e-15
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 84 4e-15
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 4e-15
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 4e-15
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 4e-15
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 83 5e-15
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 83 5e-15
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 83 5e-15
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 83 5e-15
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 5e-15
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 83 6e-15
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 83 6e-15
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 83 8e-15
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 83 8e-15
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 83 8e-15
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 83 8e-15
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 8e-15
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 83 8e-15
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 82 1e-14
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 82 1e-14
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 82 1e-14
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 81 2e-14
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 81 2e-14
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 81 3e-14
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 81 3e-14
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 81 3e-14
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 81 3e-14
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 80 5e-14
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 80 5e-14
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 80 5e-14
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 6e-14
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 80 6e-14
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 80 6e-14
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 80 6e-14
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 6e-14
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 8e-14
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 79 8e-14
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 79 1e-13
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 79 1e-13
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 79 1e-13
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 79 1e-13
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 79 1e-13
UniRef50_Q9K1Q1 Cluster: Glycerate dehydrogenase; n=6; cellular ... 79 1e-13
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 79 1e-13
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 79 1e-13
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 79 1e-13
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 79 1e-13
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 79 1e-13
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 78 2e-13
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 78 2e-13
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 78 2e-13
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 78 2e-13
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 77 3e-13
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 77 4e-13
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 77 4e-13
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 77 4e-13
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 4e-13
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 77 4e-13
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 77 4e-13
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 77 4e-13
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 77 6e-13
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 77 6e-13
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 6e-13
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 77 6e-13
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 76 7e-13
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 76 7e-13
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 7e-13
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 76 1e-12
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 1e-12
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 1e-12
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 76 1e-12
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 76 1e-12
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 75 1e-12
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 75 1e-12
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 75 1e-12
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 75 1e-12
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 75 2e-12
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 75 2e-12
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 74 3e-12
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 74 3e-12
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 3e-12
UniRef50_Q8ECR2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 74 3e-12
UniRef50_Q6F943 Cluster: Erythronate-4-phosphate dehydrogenase; ... 74 3e-12
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 5e-12
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 5e-12
UniRef50_Q87MN8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 73 5e-12
UniRef50_P30799 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 73 5e-12
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 73 7e-12
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 73 7e-12
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 73 7e-12
UniRef50_Q0FUK3 Cluster: Predicted dehydrogenase; n=3; Rhodobact... 73 9e-12
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 9e-12
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 73 9e-12
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 72 1e-11
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_A6G855 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 1e-11
UniRef50_A1RBK7 Cluster: Putative 2-hydroxyacid-family dehydroge... 72 1e-11
UniRef50_A1SW94 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 1e-11
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 72 1e-11
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 72 2e-11
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 72 2e-11
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 72 2e-11
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 2e-11
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 72 2e-11
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 71 2e-11
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 71 2e-11
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 71 2e-11
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 71 2e-11
UniRef50_O24922 Cluster: Phosphoglycerate dehydrogenase; n=4; He... 71 2e-11
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 71 2e-11
UniRef50_A3Y4H8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 71 2e-11
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 71 2e-11
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 71 2e-11
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 71 2e-11
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 71 3e-11
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 71 3e-11
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 71 3e-11
UniRef50_Q2S0U3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 71 3e-11
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 71 3e-11
UniRef50_Q82ZC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 4e-11
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 4e-11
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 71 4e-11
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 70 5e-11
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 70 5e-11
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 70 5e-11
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 70 5e-11
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 70 5e-11
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 70 5e-11
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 70 6e-11
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 70 6e-11
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 70 6e-11
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 70 6e-11
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 70 6e-11
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 8e-11
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 69 8e-11
UniRef50_Q3IF36 Cluster: Erythronate-4-phosphate dehydrogenase; ... 69 8e-11
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 69 8e-11
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 69 1e-10
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 69 1e-10
UniRef50_Q11GX7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 69 1e-10
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 69 1e-10
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q22CX9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 69 1e-10
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 68 2e-10
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 68 2e-10
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 68 2e-10
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;... 68 3e-10
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 3e-10
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 68 3e-10
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 68 3e-10
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 68 3e-10
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 67 3e-10
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 67 3e-10
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 3e-10
UniRef50_Q3IFC5 Cluster: 2-hydroxyacid dehydrogenase family prot... 67 3e-10
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 3e-10
UniRef50_A3XKE7 Cluster: D-lactate dehydrogenase; n=3; Bacteria|... 67 3e-10
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 3e-10
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 67 5e-10
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 67 5e-10
UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4; Gamma... 67 5e-10
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 67 5e-10
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 67 5e-10
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 67 5e-10
UniRef50_UPI000023E18D Cluster: hypothetical protein FG04024.1; ... 66 6e-10
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 66 6e-10
UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 66 6e-10
UniRef50_A5G073 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 66 6e-10
UniRef50_Q6LNU2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 66 6e-10
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 66 8e-10
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 66 8e-10
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 66 8e-10
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 66 8e-10
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 66 1e-09
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 66 1e-09
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 66 1e-09
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_Q03UK9 Cluster: Lactate dehydrogenase; n=3; Leuconostoc... 65 1e-09
UniRef50_A6Q6K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 65 1e-09
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 65 2e-09
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 65 2e-09
UniRef50_Q87JV4 Cluster: D-lactate dehydrogenase; n=6; Vibrio|Re... 65 2e-09
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 65 2e-09
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 65 2e-09
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 65 2e-09
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 64 2e-09
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 64 2e-09
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 64 2e-09
UniRef50_A6PLZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ... 64 3e-09
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 64 3e-09
UniRef50_Q4FV16 Cluster: Erythronate-4-phosphate dehydrogenase; ... 64 3e-09
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10; Bacteria... 64 4e-09
UniRef50_A7CUT0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 64 4e-09
UniRef50_A1HMH1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A0YAX4 Cluster: Phosphoglycerate dehydrogenase and rela... 64 4e-09
UniRef50_Q9RJA1 Cluster: Putative 2-hydroxyacid-family dehydroge... 63 6e-09
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 63 6e-09
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 63 6e-09
UniRef50_Q7VRU9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 63 6e-09
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 63 7e-09
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 63 7e-09
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 7e-09
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 7e-09
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 63 7e-09
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 7e-09
UniRef50_Q92AX6 Cluster: Lin1792 protein; n=8; Listeria|Rep: Lin... 62 1e-08
UniRef50_Q5LSR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ... 62 1e-08
UniRef50_Q1FLB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q13QJ6 Cluster: Putative dehydrogenase; n=1; Burkholder... 62 1e-08
UniRef50_Q54UF7 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN... 62 1e-08
UniRef50_Q9I3W9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 62 1e-08
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 62 1e-08
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 62 2e-08
UniRef50_Q8RC97 Cluster: Phosphoglycerate dehydrogenase and rela... 62 2e-08
UniRef50_Q2BM60 Cluster: Erythronate-4-phosphate dehydrogenase; ... 62 2e-08
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_A5V093 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_A7PQ72 Cluster: Chromosome chr18 scaffold_24, whole gen... 62 2e-08
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v... 62 2e-08
UniRef50_Q82W00 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q2B326 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 61 2e-08
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 61 2e-08
UniRef50_A5KMM3 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 61 2e-08
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 61 2e-08
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 218 bits (532), Expect = 1e-55
Identities = 100/172 (58%), Positives = 127/172 (73%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ HD L+VRS T+VT +V+ A LK+VGRAG GVDNID+ +A + G+ V+N PG N+
Sbjct: 43 ELQKHDGLIVRSETKVTADVIAASPNLKLVGRAGTGVDNIDIPAATRNGILVLNTPGGNS 102
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+SACELTC ++ LAR+VV A ++K GRWDR LY G EL+GK L ++G GR+GREVA R
Sbjct: 103 VSACELTCAVISALARNVVQAGQSMKEGRWDRKLYAGRELSGKALGVVGFGRIGREVAHR 162
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M AFGM II +DPF + +Q AQ T ELEDIW ADYIT+HTPLI T+N
Sbjct: 163 MKAFGMEIIAYDPFFTKEQAAQIGVTKGELEDIWKNADYITVHTPLIPQTKN 214
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/38 (50%), Positives = 28/38 (73%)
Frame = +2
Query: 59 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKE 172
M V+++SVL+ D V +CA LL ++G+ TTK K+SKE
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKE 38
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 213 bits (521), Expect = 3e-54
Identities = 96/172 (55%), Positives = 129/172 (75%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ NH+ L+VRS T+VT +V L+VVGRAG GVDNID+++A +KGV V+N PG N+
Sbjct: 43 ELQNHEGLIVRSETKVTADVFACCPNLRVVGRAGTGVDNIDLEAATRKGVIVLNTPGGNS 102
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+SACELTC L+ LAR+V A +LK GRWDR LY+G EL+GKTLA+LG+GR+GREV R
Sbjct: 103 ISACELTCALISNLARNVTQAVQSLKDGRWDRKLYSGFELSGKTLAVLGMGRIGREVTRR 162
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M A+GM +I FDP ++++ + L++IWP+ADYIT+HTPLI T+N
Sbjct: 163 MQAYGMRVIAFDPLLTSEDANYLNVEKFSLDEIWPMADYITVHTPLIPQTKN 214
Score = 41.5 bits (93), Expect = 0.019
Identities = 21/39 (53%), Positives = 26/39 (66%)
Frame = +2
Query: 59 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKER 175
M ++SVLI D V A C ELL +GI TTK K+SKE+
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEK 39
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 206 bits (503), Expect = 4e-52
Identities = 96/171 (56%), Positives = 124/171 (72%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
EIP +D L+VRSAT+V+++V+ AG LK++GRAG GVDNID +A GV V+N PG N
Sbjct: 44 EIPKYDGLIVRSATKVSEDVIKAGKNLKIIGRAGTGVDNIDTVAASLHGVLVMNTPGGNT 103
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
LSA E TC L+ LARH+ AS + K G+W+R + G+EL GKTLAI+GLGR+GREVA R
Sbjct: 104 LSAAEHTCALISSLARHIPQASASTKEGKWERKQFMGNELFGKTLAIIGLGRIGREVALR 163
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
M ++G+ IG+DP VS A+ + ME E IWPLADYIT+H PLI T+
Sbjct: 164 MQSYGVKTIGYDPLVSPQDAAESNIEWMETEKIWPLADYITVHVPLIPPTK 214
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 206 bits (502), Expect = 5e-52
Identities = 92/170 (54%), Positives = 130/170 (76%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ + + L+VRSAT+VT +V++A KL+VVGRAG GVDN+D+++A +KG+ V+N P N+
Sbjct: 44 ELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNS 103
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
LSA ELTC +++ LAR + A+ ++K G+W+R + G+EL GKTL ILGLGR+GREVATR
Sbjct: 104 LSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATR 163
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
M +FGM IG+DP +S + A F + LE+IWPL D+IT+HTPL+ ST
Sbjct: 164 MQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPST 213
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 186 bits (452), Expect = 6e-46
Identities = 84/171 (49%), Positives = 125/171 (73%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P +DAL+VRSAT+VT EVL AG +L+VVGRAG GVDNID+++A ++G+ V+NAP +N++
Sbjct: 39 LPEYDALIVRSATRVTAEVLAAGTRLRVVGRAGTGVDNIDLEAATRQGIMVVNAPASNSV 98
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ ELT L+L LARH+ A +++ AG+W+R + G E+ KTL ++GLGR+G EVA R
Sbjct: 99 AVAELTIALILSLARHIPQAHSSVVAGKWERNRFMGFEVRNKTLGLVGLGRIGAEVARRA 158
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M+++ +DP VS ++ AQ T LE++ AD ++LH PLI++TRN
Sbjct: 159 RGLEMHVVAYDPVVSTERAAQLGATLAPLEEVLAQADIVSLHVPLIDATRN 209
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 184 bits (447), Expect = 2e-45
Identities = 79/172 (45%), Positives = 125/172 (72%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I +++AL++RS TQVTKEV+ AG LK++GRAG G+DN+DV +A +KG+ V NAP N
Sbjct: 39 KIKDYNALIIRSETQVTKEVIAAGKNLKIIGRAGVGIDNVDVPAATEKGIIVANAPEGNT 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
++ACE T +ML ++R++ A+ +LK+G+W+R+ + G E+ KTL I+GLGR+G E+ R
Sbjct: 99 IAACEHTLSMMLAMSRNIPQANASLKSGKWERSKFMGVEVMNKTLGIIGLGRIGGEITKR 158
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+FGM ++ +DPF +A++ Q L++I+ AD+IT+HTPL ST++
Sbjct: 159 ARSFGMEVLAYDPFTTAERAQQIGARLTTLDEIYEKADFITVHTPLTPSTKH 210
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 179 bits (435), Expect = 7e-44
Identities = 83/170 (48%), Positives = 117/170 (68%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +DAL+VRS TQVT ++++AG KL+V+GRAG GVDNID+ +A G+ V+NAP N +
Sbjct: 39 IGEYDALLVRSQTQVTADIINAGKKLQVIGRAGVGVDNIDLKTATGNGIIVVNAPTGNTI 98
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA E T LML +ARH+ A+ +LK+G+W R + GSEL GKTL I+GLG +G E+A R
Sbjct: 99 SATEHTLALMLAMARHIPRANASLKSGQWKRNEFVGSELKGKTLGIVGLGNIGSEIAKRA 158
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
A M +IG+DPF+S ++ + + ED+ AD+ITLH P+ T+
Sbjct: 159 LALEMRVIGYDPFISMERAKKLQVELLPFEDLLKRADFITLHVPMTGQTK 208
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 178 bits (433), Expect = 1e-43
Identities = 84/173 (48%), Positives = 121/173 (69%), Gaps = 1/173 (0%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I + D LVVRS T+VT++V++ KLKV+GRAG GVDNIDV++A +KG+ V+NAP A++
Sbjct: 38 KIKDADVLVVRSGTKVTRDVIEKAEKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASS 97
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+S ELT LML AR++ A+ +LK G WDR + G EL GKTL ++GLGR+G++V R
Sbjct: 98 ISVAELTMGLMLAAARNIPQATASLKRGEWDRKRFKGIELYGKTLGVIGLGRIGQQVVKR 157
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTRN 701
AFGMNIIG+DP++ + + ++ ++ AD+ITLH PL TR+
Sbjct: 158 AKAFGMNIIGYDPYIPKEVAESMGVELVDDINELCKRADFITLHVPLTPKTRH 210
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 177 bits (432), Expect = 2e-43
Identities = 82/172 (47%), Positives = 118/172 (68%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I +DALV+RS TQVT+ +++A LK++GRAG GVDN+DVD+A KKG+ V NAP N
Sbjct: 54 KIKGYDALVIRSGTQVTQRIIEAADNLKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNM 113
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+SA E T +M+ ++R++ A+ +LKA W R + G E+ GKTL ++GLGR+G EVA R
Sbjct: 114 ISAAEHTIAMMMSMSRNIPQANASLKAREWKRNKFMGVEVKGKTLGVIGLGRIGSEVAKR 173
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
MN++G+DPF+S + + + +I ADYIT+HTPLI+ TRN
Sbjct: 174 AAGLEMNLMGYDPFISEKRAMELGVKLATVNEIAKEADYITVHTPLIKETRN 225
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 175 bits (426), Expect = 9e-43
Identities = 72/171 (42%), Positives = 121/171 (70%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ ++D L VRSAT+VT ++LD +LKV+GRAG GVDN+D+ +A ++GV V+N PG +++
Sbjct: 41 VGDYDGLAVRSATKVTAQLLDKAARLKVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSI 100
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ EL ++L L+RHV A+ ++KAG+W++ + G ELAG+TL ++G+G +G + R
Sbjct: 101 TVAELALSMILALSRHVAAATGSVKAGKWEKKRFQGHELAGRTLGVVGIGNIGSVLVARA 160
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A GM ++ FDPF+SA+ A+ + ++L+ +W AD +++H PL + TR+
Sbjct: 161 VALGMRVVAFDPFISAEAAAKLGASLVDLDTLWREADVVSIHVPLTDKTRH 211
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 172 bits (419), Expect = 6e-42
Identities = 78/171 (45%), Positives = 121/171 (70%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D L+VR+ T+VTK++++A L+V+ RAG GVDNIDVD+A +KG+ V+N+PG N +
Sbjct: 41 IGQYDGLIVRNQTKVTKDIIEASGNLRVIARAGVGVDNIDVDAATRKGIIVVNSPGGNTI 100
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA E T +ML L+R++ A + AG+W+R + G EL KTL I+G G++G EVA R
Sbjct: 101 SATEHTLAMMLSLSRNIPQAHKSAAAGKWEREKFKGVELFKKTLGIIGTGKIGTEVAKRA 160
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFGM ++G+DP+++ ++ A+ L++I AD+ITLHTPL++ T++
Sbjct: 161 KAFGMAVLGYDPYLTEERAAKLGIKKATLDEIAAQADFITLHTPLMKETKH 211
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 171 bits (416), Expect = 1e-41
Identities = 82/172 (47%), Positives = 115/172 (66%), Gaps = 1/172 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I N+D L++RS T + E+++ KLKVVGRAG GVDNID+ A K+G+ V N P +N +
Sbjct: 43 IENYDGLIIRSDTNIDIELMNMAKKLKVVGRAGNGVDNIDIPEATKRGIIVANTPDSNTI 102
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SACELT L+L +R++ LK G WDR + G+EL KTL I+GLGR+G VATRM
Sbjct: 103 SACELTIGLLLAQSRNIAKTDRFLKEGNWDRDSFMGTELFNKTLGIIGLGRIGSLVATRM 162
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
AF M +I +DP++S ++ +F+ + LED+ +D+IT+HTP E T N
Sbjct: 163 NAFDMKVIAYDPYISDERFKRFNVEKKDTLEDLLKESDFITIHTPRTEETIN 214
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 171 bits (416), Expect = 1e-41
Identities = 79/172 (45%), Positives = 119/172 (69%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I + DALVVRS T VTKE++DA LKV+ RAG GVDN+D+D+A +KGV V+NAP A++
Sbjct: 38 KIKDADALVVRSGTTVTKEIIDASENLKVIARAGVGVDNVDLDAATEKGVVVVNAPDASS 97
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+S EL LML AR++ A+ +LK G WDR + G E+ KTL I+GLGR+G++VA R
Sbjct: 98 ISVAELMFGLMLSAARNIPQATASLKKGEWDRKSFKGMEVYAKTLGIVGLGRIGQQVAKR 157
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AF MNI+ +DP++ + ++ + ++++ +++ITLH PL T++
Sbjct: 158 AQAFEMNIVAYDPYIPENVASELGIKLLSVDELCAESEFITLHVPLTTKTKH 209
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 171 bits (415), Expect = 2e-41
Identities = 82/171 (47%), Positives = 116/171 (67%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +++ L+VRSAT + EVL +L+++GRAG GVDNID+++A ++G+ V++ PG NA+
Sbjct: 51 IADYNILIVRSATSLPAEVLAKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAV 110
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA E TC ++L ARH+ A LK G W++ LY G EL GKTL+++GLGRVGREVA RM
Sbjct: 111 SAAEHTCAMLLAAARHIPQAMADLKQGNWNKHLYAGIELEGKTLSLIGLGRVGREVAMRM 170
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFGM I +DP ++ + A + L + AD IT+H+ L EST N
Sbjct: 171 QAFGMRTIAYDPAIADEDAALLDIELLPLHENLLRADVITIHSALDESTYN 221
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 170 bits (414), Expect = 2e-41
Identities = 83/169 (49%), Positives = 114/169 (67%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P DA++VRSAT+V E L A +LKV+ RAG G+DN+DV +A + GV V+NAP +N +
Sbjct: 49 LPEADAILVRSATKVDAEALAAARRLKVIARAGVGLDNVDVRAATQAGVMVVNAPTSNIV 108
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA EL LML ARH+ PA ALK G W RA YTG+EL KT+ I+GLGR+G VA R+
Sbjct: 109 SAAELAVALMLAAARHISPAHAALKNGEWKRARYTGTELYEKTVGIVGLGRIGVLVAQRL 168
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
AFGM I+ +DP+V A + AQ ++L+ + AD++++H P T
Sbjct: 169 SAFGMKIVAYDPYVQAGRAAQMGVRLVDLDTLLAEADFMSVHLPKTPET 217
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 170 bits (413), Expect = 3e-41
Identities = 82/171 (47%), Positives = 114/171 (66%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
IP D LVVRSAT+VT ++++AG LK++ RAG G+DNIDV A +KG+ V+N PGA+A
Sbjct: 42 IPEVDVLVVRSATKVTADIIEAGKNLKIIARAGIGLDNIDVQKAKEKGIKVLNTPGASAP 101
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
S EL LML ARH+ A+ +LK G+W++ G EL GKTL ++G G +G+EVA R
Sbjct: 102 SVAELAMGLMLACARHIARATVSLKEGKWEKKALKGKELLGKTLGLIGFGNIGQEVAKRA 161
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFGM II +DP A ++L+ ++ +D+I+LH PL ESTR+
Sbjct: 162 LAFGMKIIAYDP---AKPETDLPVEYVDLDTLFKESDFISLHVPLTESTRH 209
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 170 bits (413), Expect = 3e-41
Identities = 80/169 (47%), Positives = 110/169 (65%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D L+VRS T+V KE LD LKV+GRAG G DNID++ A K+G+ V N P N +
Sbjct: 39 IGEYDGLIVRSMTEVDKEALDKARNLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTI 98
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA E T +ML L+R++ A+ AL G WDR Y G E+ GKTL I+GLGR+G VA R
Sbjct: 99 SAVEHTIGMMLALSRNIPQANQALHEGIWDRKKYMGVEVKGKTLGIIGLGRIGSRVAVRA 158
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
AFGM +I DP++ ++ A+ + + +++ +DYITLHTPL + T
Sbjct: 159 QAFGMKVIANDPYLPPEKAAKINVPLLGFKEVLKKSDYITLHTPLTDET 207
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 169 bits (411), Expect = 6e-41
Identities = 72/171 (42%), Positives = 120/171 (70%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P +DA+++RSAT+VT++++ AG +LK++GRAG GVDNIDV +A ++G+ V+N+P N +
Sbjct: 67 VPEYDAIMLRSATKVTEKIIQAGSQLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTI 126
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A E +M+ LARH+ A+ ++K +W+R + G+E+ KTL ++GLG++G VA
Sbjct: 127 AAAEHALAMMMALARHIPDANKSVKESKWERKQFIGTEVYKKTLGVVGLGKIGSHVAGVA 186
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A GM ++ +DPF+S ++ Q CT ++L+ ++ AD+ITLH P T N
Sbjct: 187 KAMGMKLLAYDPFISQERADQIGCTLVDLDLLFSEADFITLHIPKTPETAN 237
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 169 bits (410), Expect = 8e-41
Identities = 81/171 (47%), Positives = 113/171 (66%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ DAL+VRSAT+VT+++ + LK+VGRAG GVDNID+D A K GV VINAP N
Sbjct: 37 ELHTFDALLVRSATKVTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNT 96
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+S E T ++ L RH+ A+ ++K+ W+R Y GSEL GKTL I+GLGR+G E+A R
Sbjct: 97 ISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVGSELYGKTLGIVGLGRIGSEIAQR 156
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
AFGM + FDPF++ ++ + E++ AD IT+HTPL + T+
Sbjct: 157 RGAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESADIITVHTPLTKETK 207
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 166 bits (404), Expect = 4e-40
Identities = 73/172 (42%), Positives = 113/172 (65%), Gaps = 1/172 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D + +RSAT++ + + A +LKV+GRAG GVDN+D +A +KG+ V+N P NA+
Sbjct: 40 IDQYDGIAIRSATRLPAQAIAAASRLKVIGRAGIGVDNVDTPAASQKGIIVMNTPFGNAI 99
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ EL L + ARH+ A+ + KAG+W+++ + G ELAGKT ++GLG VGR VA R+
Sbjct: 100 TTAELGVTLAMAAARHIPAATASTKAGKWEKSRFMGRELAGKTAGVIGLGNVGRLVAQRL 159
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
M ++ +DPF++ D+ ++ LED+WP D +T+HTPL + TRN
Sbjct: 160 AGLDMKVVAYDPFINKDRAISLGLEMVDKLEDLWPRVDLLTVHTPLNDHTRN 211
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 165 bits (400), Expect = 1e-39
Identities = 75/170 (44%), Positives = 111/170 (65%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+P ++A+VVRS T+V EV+ A LK++GRAG GVDNID+++A ++G+ V+NAPG N
Sbjct: 38 EVPKYEAIVVRSQTKVDAEVIQAAKNLKIIGRAGVGVDNIDINAATQRGIVVVNAPGGNT 97
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+S E LML AR + A ++K G+W+R + G EL GKT ++GLGRVG EVA R
Sbjct: 98 ISTAEHAIALMLAAARKIPQADRSVKEGKWERKKFMGIELRGKTAGVIGLGRVGFEVAKR 157
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
A MN++ +DPFVS ++ Q ++ + + +D IT+H P + T
Sbjct: 158 CKALEMNVLAYDPFVSKERAEQIGVKLVDFDTLLASSDVITVHVPRTKET 207
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 164 bits (398), Expect = 2e-39
Identities = 74/171 (43%), Positives = 115/171 (67%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D L +RSAT+VT++++ A KLKVVGRAG GVDN+D+ +A ++G+ V+N P N++
Sbjct: 48 IGEYDGLAIRSATKVTEKLIAAAKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSI 107
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ E LM +AR + A T+ +AG+W++ + G E+ GKTL ++G G +G VATR
Sbjct: 108 TTAEHAIALMFAVARQLPEADTSTRAGKWEKNRFMGVEITGKTLGVVGCGNIGSIVATRG 167
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M+++ FDPF+S + + +EL+++ AD+ITLHTPLI+ TRN
Sbjct: 168 IGLKMHVVAFDPFLSDARAQELGVEKVELDELLARADFITLHTPLIDKTRN 218
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 163 bits (397), Expect = 3e-39
Identities = 81/164 (49%), Positives = 109/164 (66%), Gaps = 2/164 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
IP +DAL+ RS T+VT EVL G +LKVVGRAG GVDNIDV +A ++GV V+N PGAN
Sbjct: 37 IPEYDALITRSETKVTAEVLARGTRLKVVGRAGVGVDNIDVAAATERGVVVVNVPGANTY 96
Query: 369 SACELTCRLMLVLARHVVPASTAL-KAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
S E L++ +AR++ A AL + GRWDR + G+EL GKTL I+GLGR+G EVA R
Sbjct: 97 STAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFVGTELHGKTLGIIGLGRIGSEVAVR 156
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLH 674
AFGM ++ +DP+V + T + L + P D++T+H
Sbjct: 157 ARAFGMRVLAYDPYVPHSRAEHLGVTLVPSLRGLLPEVDFLTIH 200
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 162 bits (394), Expect = 7e-39
Identities = 77/172 (44%), Positives = 114/172 (66%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I + DA++VRS TQVT+ +++ LK++GRAG GVDNID+++A + GV V+NAP N
Sbjct: 41 QIDSFDAILVRSQTQVTRALIEKASNLKIIGRAGVGVDNIDLEAATENGVIVVNAPNGNT 100
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
SA E T +++ L+R++ A ALK +WDR + G EL KTL I+GLGR+G EVA R
Sbjct: 101 NSAAEHTMAMIMALSRNIPQAYHALKQKQWDRKRFVGVELKQKTLGIVGLGRIGAEVAAR 160
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
MN+I +DPF + ++ Q LED+ D+IT+HTPL++ T++
Sbjct: 161 AKGQRMNVIAYDPFFTEEKAEQMGVQYGTLEDVLRAGDFITVHTPLLKETKH 212
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 162 bits (394), Expect = 7e-39
Identities = 75/168 (44%), Positives = 115/168 (68%), Gaps = 1/168 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D +++RSAT++T+EVL +LK + RAG GVDNID +A ++G+ V+N P N S E
Sbjct: 45 DGIIIRSATKLTEEVLKGQPRLKAIVRAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAE 104
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
T LM+ LAR++ PA +K G+W+R TG+++AGKTLAI+GLGR+G VA R
Sbjct: 105 QTIALMMALARNIGPAYATMKEGKWERKKLTGTQVAGKTLAIIGLGRIGLSVAHRAQGLE 164
Query: 561 MNIIGFDPFVSADQCAQFHC-TXMELEDIWPLADYITLHTPLIESTRN 701
M +IG+DPF+SA++ A++ E++++ D++T+HTPL + TR+
Sbjct: 165 MKVIGYDPFMSAERAAEYGIELYKEVDELVKHCDFLTVHTPLTDETRD 212
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 162 bits (393), Expect = 9e-39
Identities = 74/171 (43%), Positives = 112/171 (65%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
IP +D LV+RSA++VT E+L+A LKVVGRAG G+DN+DV +A KKGV V+NAP NA
Sbjct: 39 IPAYDGLVIRSASKVTAEILEAAENLKVVGRAGIGLDNVDVPAASKKGVVVMNAPDGNAT 98
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A E +M+ L R++ A+ ++KAG+W++ + G E+ K ++G+GR+GR A R
Sbjct: 99 TAAEHAVSMMMALTRNIPQATASMKAGKWEKKKFQGHEVTAKVAGVVGIGRIGRIFAERA 158
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M +I FDP + A+Q + + LE++ ADYI++H PL T++
Sbjct: 159 MGLRMKVIAFDPHMPAEQMEKIGVEPVTLEELCQRADYISVHVPLTPETKH 209
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 161 bits (392), Expect = 1e-38
Identities = 72/169 (42%), Positives = 115/169 (68%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P++DA++VRS T++T E+++ +LKV+GRAG GVDNIDV +A +G V+N PGANA
Sbjct: 40 LPDYDAVIVRSRTRITAELIENAPRLKVIGRAGTGVDNIDVKAASARGALVMNTPGANAT 99
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A E T +ML LARH+ A+ +++ GRWD+ + G+EL +TL I+GLG++G VA R
Sbjct: 100 AAAEHTIAMMLALARHIPQATQSMREGRWDKKRFMGTELFHQTLGIIGLGKIGSIVADRA 159
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ M+++G DP++ + A + L+++ +D++TLHTP T
Sbjct: 160 LSMKMDVLGHDPYIIPEAAAILGVEWVPLDELLARSDFLTLHTPSTSET 208
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 161 bits (390), Expect = 2e-38
Identities = 78/171 (45%), Positives = 114/171 (66%), Gaps = 1/171 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
IP ++ALVVRS T+VT +L A +LKVV RAG GVDN+DV+ A K G+ V+N+P N
Sbjct: 46 IPEYEALVVRSETKVTGNLLRAAKQLKVVARAGVGVDNVDVEEATKLGIVVVNSPSGNIG 105
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A E T L++ +AR++ A ++LK+G+W+R+ + G E+ GKTL+I+GLG+VG VA
Sbjct: 106 AAAEHTIALLIAMARNIPEACSSLKSGKWERSKFVGVEVKGKTLSIIGLGKVGLTVARLA 165
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTR 698
GMN+ DP+ S T + L ++ P AD++T+HTPLI ST+
Sbjct: 166 KGLGMNVNALDPYASPAVAVSASVTLVSSLSELLPTADFLTIHTPLIASTK 216
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 159 bits (387), Expect = 5e-38
Identities = 76/169 (44%), Positives = 112/169 (66%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P DAL+VRSAT V EVL A KLK+V RAG G+DN+DVD+A +GV V+NAP +N
Sbjct: 41 VPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH 100
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA E L+L +R + A +L+A W R+ ++G+E+ GKT+ ++GLGR+G+ VA R+
Sbjct: 101 SAAEHALALLLAASRQIAEADASLRAHIWKRSSFSGTEIFGKTVGVVGLGRIGQLVAARI 160
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
AFG ++I +DP+V+ + AQ M +D+ AD+I++H P T
Sbjct: 161 AAFGAHVIAYDPYVAPARAAQLGIELMSFDDLLARADFISVHLPKTPET 209
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 158 bits (384), Expect = 1e-37
Identities = 76/168 (45%), Positives = 111/168 (66%), Gaps = 1/168 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D ++VRS T++T VL+ KLK + RAG GVDNIDV +A KKG+ V+N P N +S E
Sbjct: 52 DGVIVRSNTKLTAPVLEKSEKLKAICRAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAE 111
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
T L+ L+R V A ++K G+W++ +TG +L GKT I+GLGRVGR+VA R A
Sbjct: 112 HTIALLCSLSRFVPQACASVKEGKWEKKKFTGQQLTGKTFGIIGLGRVGRQVAKRAAALE 171
Query: 561 MNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
M +IG+DPF++ + +Q++ ++ L D+ ADYIT+H L + T+N
Sbjct: 172 MKVIGYDPFITTEISSQYNIHIVKNLRDLLAQADYITIHVTLNKETKN 219
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 158 bits (383), Expect = 1e-37
Identities = 75/157 (47%), Positives = 107/157 (68%)
Frame = +3
Query: 225 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLV 404
T+VT +V + KL++VGRAG G+DN+++++A K + V+N P +LSA ELTC +++
Sbjct: 51 TKVTADVTNTAEKLQLVGRAGTGMDNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVC 110
Query: 405 LARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDP 584
L R + P G+WD+ + G+EL GKTL ILGLGR+GREV T+M AF M +GFDP
Sbjct: 111 LTRQIPP-------GKWDQEEFMGTELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDP 163
Query: 585 FVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
S + A F + LE++WPL D+IT+HTPL+ ST
Sbjct: 164 ISSPEIAASFGVQQLLLEELWPLCDFITVHTPLLLST 200
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 158 bits (383), Expect = 1e-37
Identities = 72/165 (43%), Positives = 111/165 (67%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
A+ VRS T++T+EV+ A +LKVVGRAG GVDN+DV++A ++GV V+N P N ++ EL
Sbjct: 45 AIAVRSETKITREVIAAAPQLKVVGRAGVGVDNVDVEAATERGVVVMNTPAGNTIATAEL 104
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
T +L +R V A+ +++ G+WDR ++G EL KTL ++G+GR+G EVA R AFGM
Sbjct: 105 TFTHILCGSRPVSQAAASMREGKWDRKSFSGVELFKKTLGVIGMGRIGGEVARRAVAFGM 164
Query: 564 NIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
++ +DP+++ + L++I ADYIT+H PL + T+
Sbjct: 165 KVLAYDPYLAPSRAKAMQVEVATLDEILAQADYITVHMPLTDDTK 209
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 158 bits (383), Expect = 1e-37
Identities = 70/170 (41%), Positives = 116/170 (68%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
EI +D LV+RS T+VT+E+L +LKV+GRAGAG+DN+D+++A ++G+ V+N PG N
Sbjct: 42 EISQYDGLVIRSGTKVTREILKNADRLKVIGRAGAGLDNVDLEAATERGIVVMNTPGGNT 101
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
++ E T L++ +AR + A+ + KAG+W+++ + G EL KTL I+G+G++G+ VA
Sbjct: 102 VTTAEHTMSLLMSMARRIPQANASNKAGKWEKSKFMGVELFQKTLGIVGMGKIGQHVAQI 161
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
MNII FDP+++ + + + L++++ AD+IT+HTPL T
Sbjct: 162 ARGIAMNIIAFDPYLTPEVAEKSGVHPVSLDELFQRADFITVHTPLTPET 211
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 157 bits (382), Expect = 2e-37
Identities = 72/170 (42%), Positives = 113/170 (66%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +++ L+VRS TQVT++V++ LKV+ RAG GVDNID+D+A +G+ VINAP N +
Sbjct: 42 IGDYEGLIVRSQTQVTQQVIEKASNLKVIARAGVGVDNIDIDAATLQGILVINAPDGNTI 101
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA E + ++L +AR++ A +LK W+R + G EL KTL ++G GR+G VA R+
Sbjct: 102 SATEHSVAMILAMARNIPQAHASLKNKEWNRKAFKGVELYQKTLGVIGAGRIGIGVAQRL 161
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
+FGM ++ +DP+++ D+ Q +++I AD++T+HTPL TR
Sbjct: 162 QSFGMKVLAYDPYLTEDKAQQLGVKLATIDEIARQADFVTVHTPLTPKTR 211
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 157 bits (382), Expect = 2e-37
Identities = 76/172 (44%), Positives = 111/172 (64%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
++ DAL+VRSA V +L+ +L+V+GRAG GVDNI++++A +KG+ V+N PGANA
Sbjct: 40 QLKGADALIVRSAVFVDAAMLEHADQLRVIGRAGVGVDNIELEAATRKGIAVMNTPGANA 99
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
++ E T LML LAR + A+ + AG+W++ G+EL GKTL I+GLGR+G EVA R
Sbjct: 100 IAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQGTELRGKTLGIVGLGRIGLEVARR 159
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+FGM ++ DP+VS + +++ +ADYITLH L T N
Sbjct: 160 AASFGMTLVAHDPYVSPAIAHDAKIRLADRDEVLAVADYITLHVGLTPQTAN 211
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 157 bits (381), Expect = 2e-37
Identities = 74/170 (43%), Positives = 117/170 (68%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I ++DA++VRSAT+V +E+++ G KLKV+GRAG GVDNIDV++A ++G+ V+N P N +
Sbjct: 38 IKDYDAIIVRSATKVDRELIEKGEKLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTI 97
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A ELT LML +AR++ A A G + R + G EL GKT+ I+GLGR+G VA+R+
Sbjct: 98 AAAELTIGLMLAIARNIPQAYHAALNGDFRRDRFKGVELNGKTVGIIGLGRIGSLVASRL 157
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
AF M +I +DP++ ++ + + L+++ +D+IT+H P E T+
Sbjct: 158 AAFNMRVIAYDPYMPDERFEKCGVKRVTLDELLEQSDFITIHIPKTEETK 207
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 157 bits (381), Expect = 2e-37
Identities = 70/167 (41%), Positives = 110/167 (65%), Gaps = 1/167 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA ++RS +T E L+ +L+ + RAG G DNID +A ++G+ V+N P N +S E
Sbjct: 45 DAAILRSGVTITPESLEGNTRLRALVRAGVGTDNIDKPAATRRGIVVMNTPAGNTVSTAE 104
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
T ++L ++R++ A+ +L GRWDR + G+++AGKTL I+G+GR+GREVA+R AF
Sbjct: 105 HTFAMLLAMSRNIAAANQSLVEGRWDRKKFMGTQVAGKTLGIVGMGRIGREVASRAQAFD 164
Query: 561 MNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTR 698
M+++ FDPF++ DQ + ++D+ P DY+T+HTPL TR
Sbjct: 165 MDVVAFDPFLTDDQAESLKVRRVATVDDMLPQIDYLTVHTPLTPETR 211
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 157 bits (380), Expect = 3e-37
Identities = 77/173 (44%), Positives = 112/173 (64%), Gaps = 2/173 (1%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I N AL+VR+ T+V +E++DA +LK++ RAGAG+DN+D + A +KG+ V P AN+
Sbjct: 40 KIQNTRALIVRNQTKVDRELIDAAPELKIIARAGAGLDNVDTEYAHEKGIVVCFTPDANS 99
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
LS ELT LML L R + A G W+R +TG+EL GK+ ++GLGR+G ATR
Sbjct: 100 LSVAELTIGLMLALMRKIPEARQDTLTGGWNRLKFTGTELYGKSFGLIGLGRIGSFTATR 159
Query: 546 MYAFGMNIIGFDPFVSAD--QCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
AFGMNI+ DPF+ AD Q + + T + L+D+ +D ++ H+PL TR
Sbjct: 160 AKAFGMNILAADPFLKADAPQLKKLNATLLSLDDLLAESDVVSCHSPLTPDTR 212
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 157 bits (380), Expect = 3e-37
Identities = 74/172 (43%), Positives = 110/172 (63%), Gaps = 1/172 (0%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
++ DAL+VRS T+VT+EV +A +LKVVGRAG G+DN+D+ +A + G V+NAP AN
Sbjct: 119 KVAESDALIVRSGTKVTREVFEAAKGRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTAN 178
Query: 363 ALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT 542
++A E L+ +AR+V A ++KAG+W+R+ Y G L GKTLA++G G+VG EVA
Sbjct: 179 TVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVGVSLVGKTLAVMGFGKVGTEVAR 238
Query: 543 RMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
R GM +I DP+ AD+ + + AD+++LH PL +T+
Sbjct: 239 RAKGLGMTVISHDPYAPADRARALGVDLVSFDQAISTADFVSLHMPLTPATK 290
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 155 bits (376), Expect = 1e-36
Identities = 75/170 (44%), Positives = 111/170 (65%), Gaps = 1/170 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D L+VRSAT+VT EV++A +LK +GRAG GVDNID+++A K+G+ V NAP +N +
Sbjct: 38 IGEYDGLIVRSATKVTAEVIEAAGRLKAIGRAGIGVDNIDIEAATKRGILVANAPESNTV 97
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A E T LML +AR + A +L+ G W+RA + G E+A KTL ++GLG VG VA
Sbjct: 98 AAAEHTLGLMLAVARRIPAADASLRRGEWNRAAFKGVEVAEKTLGLVGLGHVGSIVARGA 157
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIEST 695
GM ++ +DP+VS ++ + LE+I+ AD+++LH P T
Sbjct: 158 LGMGMRVLAYDPYVSEERMRSMNVERAGSLEEIFEEADFVSLHVPRTPQT 207
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 154 bits (374), Expect = 2e-36
Identities = 73/172 (42%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + DA++ RS T VTKE+L+ KLKVVGRAG GVDN+D++ A K+G+ V+N PGAN +
Sbjct: 41 IKDFDAIITRSRTPVTKELLERAEKLKVVGRAGVGVDNVDIEEATKRGILVVNTPGANTI 100
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
A ELT ML + R+ A ++ +WDR + G EL G+ L I+GLG +G +VA R
Sbjct: 101 GATELTMMHMLTIMRNGHKAHESMLNYKWDRKKFMGEELYGRILGIIGLGNIGSQVAIRA 160
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
AFGM ++ +DP++ ++ + ++ L D+ D +T+H PL T+N
Sbjct: 161 KAFGMKVMAYDPYIPREKAEKLGVKLVDNLHDMLREIDVLTIHAPLTHETKN 212
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 153 bits (372), Expect = 3e-36
Identities = 73/166 (43%), Positives = 110/166 (66%), Gaps = 1/166 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA VVRS T+VT+E+++ LKV+ RAG GVDNIDV +A ++G+ V+NAP ++++S E
Sbjct: 43 DAWVVRSGTRVTRELIEEAKNLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAE 102
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
T L+L LAR + A +++ G WDR + G ELAGKTL ++GLGR+G++VA R AF
Sbjct: 103 HTMGLILALARKIPQADRSVRRGEWDRKRFMGVELAGKTLGLIGLGRIGQQVAKRAKAFE 162
Query: 561 MNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIEST 695
M + +DP++ + + ELE++ AD +++H PL E T
Sbjct: 163 MEVTAYDPYIPEKVAEELGVELVDELEELLERADVVSIHVPLTEET 208
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 150 bits (363), Expect = 4e-35
Identities = 72/166 (43%), Positives = 107/166 (64%), Gaps = 1/166 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 377
DAL+VRS T+V++EV +A +LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A
Sbjct: 153 DALIVRSGTKVSREVFEASSGRLKVVGRAGVGIDNVDLAAATEHGCLVVNAPTANTVAAA 212
Query: 378 ELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
E L+ +AR+V A ++K+G+W R Y G L GKTLA++G G+VG EV R
Sbjct: 213 EHGIALLTAMARNVAQADASVKSGKWQRNKYVGVSLVGKTLAVMGFGKVGSEVTRRAKGL 272
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
GM++I DP+ +AD+ + ++ AD+I+LH PL +T
Sbjct: 273 GMHVIAHDPYAAADRARAIGVELVGFDEAISTADFISLHMPLTPAT 318
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 150 bits (363), Expect = 4e-35
Identities = 72/169 (42%), Positives = 107/169 (63%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + +ALVVRS T V + V +A L +VGRAG GVDNID+D+A + GV V NAP N
Sbjct: 43 ITDVNALVVRSGTDVNEAVFEAASDLIIVGRAGIGVDNIDIDAATEHGVIVANAPEGNVR 102
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+A E T + AR + A L+ G W ++ Y G+E+ GKTL ++GLGRVG+EVA R+
Sbjct: 103 AAAEHTVAMTFAGARSIPQAHARLRTGEWAKSEYLGTEVNGKTLGVVGLGRVGQEVAKRL 162
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ GM+++ +DP++S D+ + +E + A+++T+HTPL T
Sbjct: 163 ESLGMDLVAYDPYISEDRAERLGAELVEFDTCLERAEFLTVHTPLTSET 211
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 146 bits (354), Expect = 5e-34
Identities = 78/183 (42%), Positives = 111/183 (60%), Gaps = 13/183 (7%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
++ DAL+VRS T+VT+EVL+AG +L+VVGRAG G+DN+D+ +A + G V+NAP AN
Sbjct: 114 KVAQFDALIVRSGTKVTREVLEAGRGRLRVVGRAGVGIDNVDLQAATEAGCLVVNAPTAN 173
Query: 363 ALSACELTCRLMLVLARHVVPASTALKA------------GRWDRALYTGSELAGKTLAI 506
++A E L+ +AR+V A ALKA G+W R Y G L GKTLA+
Sbjct: 174 TVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFTAQGKWQRTKYVGVSLVGKTLAV 233
Query: 507 LGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLI 686
+G G+VG EVA R GM++I DP+ AD+ + ++ AD+I+LH PL
Sbjct: 234 MGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGAELVSFDEAIGRADFISLHMPLT 293
Query: 687 EST 695
+T
Sbjct: 294 PAT 296
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 145 bits (352), Expect = 8e-34
Identities = 74/172 (43%), Positives = 110/172 (63%), Gaps = 1/172 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I D L+VRS T+V +EV++A KLKV+ RAG+G+DNID+++A +KG+ V+NAP A
Sbjct: 41 IKGFDVLIVRSRTKVRREVIEAADKLKVIARAGSGLDNIDLEAAKEKGIKVVNAPDALKN 100
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ EL +M+VLAR + L G W++ + G ELAGKTL ++G GR+GREVA +
Sbjct: 101 AVAELVIGMMVVLARRAHYSYRKLLEGEWEKVM--GFELAGKTLGVVGFGRIGREVAKKA 158
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCT-XMELEDIWPLADYITLHTPLIESTRN 701
A GMN+I +D ++ + +LE++ +D ++LH PL E TRN
Sbjct: 159 KALGMNVIAYDVVDLSETAKEMGVEFTQDLEELLRKSDVVSLHVPLTEQTRN 210
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 144 bits (348), Expect = 2e-33
Identities = 67/170 (39%), Positives = 107/170 (62%), Gaps = 1/170 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
I +DAL++RSAT+VT ++L+AG KLK V RAG G+DN+D+ +A K GV V+N P N
Sbjct: 42 IGQYDALIIRSATKVTADILEAGAPKLKAVARAGIGLDNVDIPAATKHGVAVMNTPEGNV 101
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
++ E T +M+ L R++ + +L++G+W++ G E+ KTL ++G G++G VA R
Sbjct: 102 VTTAEHTIAMMMALTRNIPQGTLSLRSGQWEKKKLQGREVFNKTLGVIGFGKIGSIVADR 161
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
MN+I FDP ++ + L+D++ ADYIT+H P ++ T
Sbjct: 162 ARQLKMNVIVFDPNIARTTIENEGFEYVSLDDLFARADYITVHVPKLKQT 211
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 143 bits (347), Expect = 3e-33
Identities = 72/172 (41%), Positives = 110/172 (63%), Gaps = 2/172 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+P++DAL+ RS T+V +E+LDA G +LKV+GR G GVDNID++ A ++G+ V+NAP +N
Sbjct: 55 LPDYDALITRSRTKVDRELLDAAGPRLKVIGRGGVGVDNIDLEYASRRGLLVLNAPESNN 114
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+SA EL ++ AR + + +AG WDR + G EL KTL I+GLGR+G VA R
Sbjct: 115 VSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLGLELTDKTLGIVGLGRIGSIVADR 173
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHC-TXMELEDIWPLADYITLHTPLIESTR 698
MN++ +DP+V ++ + L+++ D +T+HTPL + TR
Sbjct: 174 AQGLHMNVVAYDPYVPENKFERLGVQRAASLDELLGQVDALTVHTPLTDETR 225
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 143 bits (346), Expect = 4e-33
Identities = 68/132 (51%), Positives = 85/132 (64%)
Frame = +3
Query: 303 IDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSE 482
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 483 LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADY 662
L GKTL I+GLGR+GREVA RM +FGM IGFDP V A++ Q++ LE +WP DY
Sbjct: 106 LYGKTLGIVGLGRIGREVAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLEQMWPRCDY 165
Query: 663 ITLHTPLIESTR 698
IT+HTPLI T+
Sbjct: 166 ITVHTPLIPQTK 177
Score = 37.1 bits (82), Expect = 0.42
Identities = 17/38 (44%), Positives = 21/38 (55%)
Frame = +2
Query: 59 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKE 172
M +K VLI D V +CAE+L GI K+SKE
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKE 38
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 141 bits (341), Expect = 2e-32
Identities = 71/171 (41%), Positives = 107/171 (62%), Gaps = 1/171 (0%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I D L+VRSAT+VTKE+L+ KLK+V RAG G+DNIDVD+A KG+ V+N PG N+
Sbjct: 39 KIKEIDVLIVRSATKVTKEILEHADKLKIVARAGMGLDNIDVDTAKLKGITVLNTPGQNS 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
LS EL ++L + RH+ + LK +W++ G EL+ KT I+G G VG+ +A
Sbjct: 99 LSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEGFELSQKTFGIIGFGYVGKNLAQL 158
Query: 546 MYAFGMNIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ F N + +D F +SA++ ++ + LE++ +D I+LH P E T
Sbjct: 159 LKGFQTNTLVYDVFEISAEEQKNYNVRQVSLEELLQNSDIISLHIPKNEKT 209
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 141 bits (341), Expect = 2e-32
Identities = 68/164 (41%), Positives = 106/164 (64%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P DAL+V VT EV++AG +L+V+ + G GVDNID+D+A +G+ V+ APG+N+
Sbjct: 47 VPEADALIV-GMDLVTAEVIEAGPRLRVIAKHGVGVDNIDLDAARARGIPVVFAPGSNSR 105
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ ELT LM+ AR + A TA+ AG W + LY G ELAG+TL ++G GR+GR +A
Sbjct: 106 AVAELTFGLMIAAARRIAAAHTAVVAGDWPK-LY-GPELAGRTLGVIGFGRIGRLLAGYA 163
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
AFGM ++G+DPF+ + + + + ++D+++LH P
Sbjct: 164 QAFGMTVVGYDPFLDDGELTERGVRPVSFSECLAMSDFVSLHLP 207
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 138 bits (335), Expect = 9e-32
Identities = 65/169 (38%), Positives = 103/169 (60%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I N++ L+ R ++ K+++DAG LK++ R G G+DN+DV+ A KKG+ V++AP A +
Sbjct: 39 IKNYNILIFRGRLKIDKDIMDAGQNLKILARYGVGLDNVDVEYAVKKGIAVVSAPNAPSQ 98
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
S ELT L+ +AR + + +KAG W + Y G E+AGKT+ I+G GR+GR VA
Sbjct: 99 SVAELTIGLLFSVARRIPLLNAKVKAGEWPKGKYIGIEIAGKTMGIVGFGRIGRFVAQMA 158
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ GMNI+ D + + A+ + LE++ +D +T+H PL T
Sbjct: 159 KSLGMNILASDVIDVSKEVAKIGGRQVPLEELLRQSDVVTIHVPLTPET 207
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 136 bits (328), Expect = 6e-31
Identities = 67/170 (39%), Positives = 107/170 (62%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + DAL+V + +VT++V++AG KLKV+ R G G DN+D+++A KKG+ V N P AN
Sbjct: 49 VKDADALIVGN-DKVTEDVINAGKKLKVISRYGVGYDNVDLNAAKKKGIVVTNTPNANNN 107
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
S +L LMLVLAR+++ +K+G W R + G+E+ GKTL I+GLG++G+ VA R
Sbjct: 108 SVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--GTEIYGKTLGIIGLGKIGKGVAKRA 165
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
F MN++ +D + ++ T E++ +D +T+H PL T+
Sbjct: 166 KGFDMNVLCYDVYPDLKFSEEYGVTYCSFEELLKQSDIVTIHVPLTPETK 215
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 132 bits (319), Expect = 8e-30
Identities = 65/170 (38%), Positives = 103/170 (60%)
Frame = +3
Query: 192 PNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALS 371
P+ + ++VRS ++T EV+D LK V RAGAG + ID+ A K + V+N PGAN+ +
Sbjct: 42 PDTEGMIVRSE-KLTPEVIDLFPNLKAVVRAGAGYNTIDIQYARSKDITVMNTPGANSNA 100
Query: 372 ACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMY 551
E +M+ AR + + +AG W +A G EL GKT+ I G G +G+ +A R+
Sbjct: 101 VAEEAVGMMISCARFFIEGDRSTRAGEWKKAQLQGFELTGKTVGIAGFGNIGQLLAKRLS 160
Query: 552 AFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
F ++I+ +DPFVS D+ A+F + LE+++ +D+I+LH P + T N
Sbjct: 161 GFEVDILVYDPFVSEDKLAEFGAKNVSLEELFAGSDFISLHMPATKETAN 210
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 130 bits (315), Expect = 2e-29
Identities = 70/170 (41%), Positives = 103/170 (60%), Gaps = 4/170 (2%)
Frame = +3
Query: 183 MEIPNHDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 350
++I D LVVRSAT+VTKEV+DA G KLK++ RAG GVDNIDV A KG+ V N
Sbjct: 37 VKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARDKGLTVNNT 96
Query: 351 PGANALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 530
P A++ S EL M ++R + A+ ++ G+W++ YTG+E+ GKTL ++G GR+ R
Sbjct: 97 PNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTGTEIFGKTLGLIGFGRIAR 156
Query: 531 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
EVA R A GM +I ++ + ++ + AD+++LH P
Sbjct: 157 EVAKRAEALGMKVI-YNDICGKVVGYDSYEFYDDINGLLREADFVSLHIP 205
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 129 bits (312), Expect = 6e-29
Identities = 63/171 (36%), Positives = 101/171 (59%), Gaps = 2/171 (1%)
Frame = +3
Query: 195 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 374
N D +++R+ T T+E+++A +LK++ R G G DN+D+ +A + V V + PG+N+ +
Sbjct: 41 NIDGVILRAET-FTREMIEASPRLKIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAV 99
Query: 375 CELTCRLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVATRM 548
E L+L L R ++PA+ + AG W R G EL+G+TL I+G G +G+ VAT
Sbjct: 100 AEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDLVGFELSGRTLGIVGFGAIGKRVATIA 159
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
FGM ++ DP +A +EL+ ++ AD ITLH PL+ TR+
Sbjct: 160 NGFGMRVLASDPIATAADAEAAGAVLVELDTLYDGADIITLHAPLLSGTRH 210
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 128 bits (308), Expect = 2e-28
Identities = 66/169 (39%), Positives = 101/169 (59%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++ R+ +++VL+ +LK++ R G GVDNIDV +A K G+ V N P AN + E
Sbjct: 45 DAIIARTEIY-SEKVLENANRLKIIARHGIGVDNIDVKAATKYGIKVTNTPSANINAVAE 103
Query: 381 LTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATR-MYA 554
L ML RH++P A++AG +D R G EL GKT+ I+G G +GR +A +
Sbjct: 104 LVLTFMLASTRHLLPIDEAVRAGNFDIRNQLFGYELNGKTVGIIGFGNIGRLIAEKCRLG 163
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
GMNI+ FDP+V+A+ + LED+ ++D +TLH P + +T +
Sbjct: 164 LGMNIVVFDPYVTAESVEPYVELTESLEDLLRISDVVTLHVPYVRATHH 212
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 127 bits (307), Expect = 2e-28
Identities = 59/166 (35%), Positives = 102/166 (61%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ L+VRS ++T E++D +LK++ RAGAG + ID+ A K + V+N PGAN+ + E
Sbjct: 44 EVLIVRSE-KITPEIIDLLPQLKLIVRAGAGFNTIDIKYARKHDIDVMNTPGANSNAVAE 102
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
+ML +RH++PA + + G W+++ + G EL GKT+ ILGLG +G+ + R+ F
Sbjct: 103 EVVAMMLAASRHLIPADISTRKGDWEKSKFMGRELTGKTVGILGLGHIGQLLVKRLAGFE 162
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
M ++G+DP +S + ++ I+ +D+++LH P + TR
Sbjct: 163 MKVLGYDPMLSPALADKLGVELTTVDRIFAESDFVSLHIPENDETR 208
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 125 bits (301), Expect = 1e-27
Identities = 68/169 (40%), Positives = 103/169 (60%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DAL+V VT E+++ LK++ + G GVDNID+++A KKG+ V GAN+LS E
Sbjct: 44 DALIV-GTHPVTAEMVENS-SLKIIAKHGVGVDNIDLEAATKKGIPVTITAGANSLSVAE 101
Query: 381 LTCRLMLVLARHVVPASTAL-KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
LT + L+R +V A L RW+ + G E++GKTL ++G G +GREV +
Sbjct: 102 LTIAFIFALSRGLVWAHNKLFLERRWEGTV--GQEVSGKTLGVVGFGSIGREVVKKAVCL 159
Query: 558 GMNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTRN 701
GMN++ +DP+VS D T + +LE + +D+++LH PL EST+N
Sbjct: 160 GMNVLVYDPYVSKDSVRLLEATPVDDLEQLLKESDFVSLHVPLNESTKN 208
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 125 bits (301), Expect = 1e-27
Identities = 60/169 (35%), Positives = 100/169 (59%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I N+DAL+VR T V++E++ A +LK++ RAG GV+NI +D+A KG+ V N P +
Sbjct: 40 INNYDALIVRGGTTVSEELIFAAKRLKIIARAGIGVENIAMDAANIKGIVVTNTPLGSTT 99
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ E +M+ LAR + A ++ G+W + GS++ KTL ++G G++GR V
Sbjct: 100 TIAEHAIAMMMSLARLIPQAHESMSQGKWQSTEFLGSDINDKTLGVIGGGKIGRRVIEYA 159
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
M++ +DP++S + + + + LED+ AD+I+LH PL T
Sbjct: 160 RGLHMHVNLYDPYLSEEVITRLGASKVSLEDLLSTADFISLHLPLTLET 208
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 123 bits (296), Expect = 5e-27
Identities = 59/159 (37%), Positives = 95/159 (59%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
AL++RS T++ +E+L +L+++ +G D+ID+++ K GV V++ P AN SA +L
Sbjct: 46 ALIIRSRTKIDEELLKKARQLQLIVTCTSGFDHIDLEATQKWGVTVMHTPTANIESAAQL 105
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
T L+L ++ A +KAG W+R TG ELAG+ I+GLGR+G VA AFGM
Sbjct: 106 TWGLVLSCVNNIQAAHKMVKAGEWNRDQITGIELAGRNYGIVGLGRIGSRVAELAQAFGM 165
Query: 564 NIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
N++ +DP+ + + H + E++ AD I+ H P
Sbjct: 166 NVVAYDPYQEDEVFERLHIPRLSYEEVLKTADVISFHVP 204
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 122 bits (295), Expect = 6e-27
Identities = 66/170 (38%), Positives = 95/170 (55%), Gaps = 3/170 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DAL+VR+ TQV +L+ L+VVGR G G+DNIDV + +G+ VI A GANA S E
Sbjct: 46 DALIVRNRTQVDAALLERAPALRVVGRLGVGLDNIDVAACRDRGIRVIPASGANARSVAE 105
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGREVATRMYAF 557
+L R S + G+W RA L G E GKTL ++G G +GR+ A AF
Sbjct: 106 YVVTTAALLLRGAYLGSAEVAGGKWPRARLSEGREALGKTLGLIGFGDIGRQAAALAQAF 165
Query: 558 GMNIIGFDPFVSADQ--CAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
GM ++ DP ++ D + M L+ + +D ++LH PL+ +TR+
Sbjct: 166 GMRVVAHDPMLAPDDPVWSATGVVCMTLDALLAQSDAVSLHVPLVAATRH 215
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 122 bits (295), Expect = 6e-27
Identities = 64/158 (40%), Positives = 94/158 (59%)
Frame = +3
Query: 228 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
+V E L+A LK++ + G GVD+ID+ +A +G+ V NAPG NA S +L ML L
Sbjct: 61 KVYAEDLEAAPNLKLIIKHGTGVDSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSL 120
Query: 408 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
AR +V A + G W + G ++ GKTL +LGLG++G+ V R F MNI+G+D
Sbjct: 121 ARQIVSADKRTRDGFWGTVM--GKDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYDLV 178
Query: 588 VSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ ++ LE+I ADYI++H PL+EST+N
Sbjct: 179 HHSQFEKEYRVRAATLEEIMSEADYISVHLPLLESTKN 216
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 122 bits (294), Expect = 9e-27
Identities = 64/165 (38%), Positives = 94/165 (56%), Gaps = 3/165 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + DAL+ +T+VTKEV+DA LK+V GAG DNID AG+KG+ V N P +
Sbjct: 41 VKDKDALLSLLSTKVTKEVIDAAPSLKIVANYGAGYDNIDYTYAGEKGIAVTNTPKVSTE 100
Query: 369 SACELTCRLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILGLGRVGREVA 539
+ ELT L+L AR + T + W + G E+ GKT+ I+GLG +G+ VA
Sbjct: 101 ATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPLFFLGREVHGKTIGIIGLGEIGKAVA 160
Query: 540 TRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLH 674
R AFGMNI+ P + ++ T + LE++ AD+IT++
Sbjct: 161 KRAKAFGMNILYTGPNRKPEAESELEATYVTLEELLQTADFITIN 205
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 122 bits (293), Expect = 1e-26
Identities = 61/173 (35%), Positives = 96/173 (55%), Gaps = 1/173 (0%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E P + ++VRS T +T E++ + K++ R G G+DNID+ +A GV VINA
Sbjct: 42 EAPGYSIIIVRSRTTITGEIIRSAKDCKIIARVGVGLDNIDLAAAESAGVRVINAVEGAT 101
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+ EL +ML +AR + A ++ G+W + G+EL GK L I+GLG +GR +
Sbjct: 102 TAVSELVLGMMLCMARQIPRADRGIRGGKWLKGELGGTELKGKYLGIVGLGNIGRRLGRL 161
Query: 546 MYAFGMNIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
MNIIG D + A+ + +L + +DY++LH PL++STR+
Sbjct: 162 ARGMNMNIIGHDVVPIDAEFSREVGLMKTDLNTLLGSSDYVSLHVPLLDSTRH 214
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 121 bits (291), Expect = 2e-26
Identities = 68/170 (40%), Positives = 94/170 (55%), Gaps = 1/170 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVK-LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
I DALV VT +V+ AG+ LK++ + G G + IDV +A G+ V PGAN
Sbjct: 46 IKGMDALVA-GMDAVTAKVIAAGLPTLKIIAKHGVGYNTIDVAAAAAYGIPVTITPGANN 104
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+S EL LML +ARH+ ++ G W R TGSEL GK L I+G+G +G EVA R
Sbjct: 105 ISVAELAIGLMLAVARHIPQMDGIVRRGGWSRM--TGSELYGKVLGIIGMGSIGCEVAKR 162
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+AFGM II +D D + T + + D AD+++LH P + T
Sbjct: 163 AHAFGMKIIAYDIRPRQDMIENYGVTYLPMADCLAQADFLSLHAPALPET 212
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 119 bits (287), Expect = 6e-26
Identities = 57/166 (34%), Positives = 97/166 (58%), Gaps = 1/166 (0%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+VVR + ++ + A L+V+ + G GVDNIDVD+A ++ + V+ A GANALS E
Sbjct: 76 VVVRMG-RFSEAAIKAAPSLRVLSKHGVGVDNIDVDAASRREIPVVVAAGANALSVAEHA 134
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
L+ + + +VP + ++AGRW++A Y+G ELAG + ++G G + R+ A FG+
Sbjct: 135 ITLLFAVVKRIVPLDSGIRAGRWEKAGYSGKELAGMIIGLVGFGAIARQTAVFARGFGLK 194
Query: 567 IIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTRN 701
+ +DPF + + +++D+ +D ++LH PL TRN
Sbjct: 195 VQAYDPFTDETAFVEAGVHRVADVDDLISSSDILSLHCPLTPDTRN 240
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 118 bits (285), Expect = 1e-25
Identities = 63/172 (36%), Positives = 102/172 (59%), Gaps = 2/172 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I ++D + VR+ ++ +E++DAG KLK + RAGAG+DNID A ++ + +INAP N
Sbjct: 42 IADYDGIAVRTKFRIDRELIDAGTKLKFIARAGAGLDNIDEAVALERNIHLINAPEGNMD 101
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ E LML L + A ++ G+WDR G EL GKT+ I+G G +G +A ++
Sbjct: 102 AVGEHAVGLMLSLMNNFRNADMEIRKGKWDREGNRGYELKGKTVGIIGYGFMGSSLARKL 161
Query: 549 YAFGMNIIGFDPFVS--ADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
FG+ +I +D + + +DQ A+ + +E+I L+D ++ H PL TR
Sbjct: 162 SGFGVQVIAYDKYKTGFSDQYAR----EVSMEEIVKLSDVLSFHIPLTNETR 209
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 118 bits (284), Expect = 1e-25
Identities = 59/167 (35%), Positives = 94/167 (56%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D ++VR ++ +V+ A KLK + + G G DNIDV++A ++G+ V A GAN+ S E
Sbjct: 58 DGIIVRQG-KIDDQVIGASQKLKAIAKHGVGYDNIDVEAADRRGIPVFVARGANSQSVAE 116
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L LM +AR + +K G WD+A G++L G++L ++G G +GR + +
Sbjct: 117 LAFALMFAVAREIPHLDARIKTGHWDKATTKGAQLLGRSLGVIGFGEIGRILVGLVQPLH 176
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M + FDP++ AD L++I +D I+LH PL+ TRN
Sbjct: 177 MEVRIFDPYMPADAEISGAERAGSLDEILTASDVISLHCPLMPQTRN 223
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 117 bits (282), Expect = 2e-25
Identities = 60/168 (35%), Positives = 100/168 (59%), Gaps = 2/168 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA+++R+ +++T+EV++ LK++ R GAGVDNIDV++A +KG+ V N P N LS E
Sbjct: 43 DAIILRTRSKITREVIENAPHLKIISRTGAGVDNIDVNAATEKGILVCNLPAVNNLSVAE 102
Query: 381 LTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRMY-A 554
T ++L L++ + A+++G W R E+ GK L I+G+G +G VA + +
Sbjct: 103 HTIAMILNLSKQLSLMDKAVRSGNWGARNSNISVEIEGKVLGIVGMGNIGSLVAKKCHDG 162
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
GM I+ +DP+V + E+++ +D++TLH P I TR
Sbjct: 163 LGMKIVAYDPYVKEKFRGYDYKFVDTREELFKESDFVTLHCPDIPETR 210
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 116 bits (280), Expect = 4e-25
Identities = 64/171 (37%), Positives = 91/171 (53%), Gaps = 2/171 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
IP D + RS+T V L++ K+ + RAG GVDN+D+ + K+G+ V+N P AN +
Sbjct: 44 IPLADVAITRSSTDVDAAFLESAKKITAIVRAGVGVDNVDIPGSSKQGIVVMNVPTANTI 103
Query: 369 SACELTCRLMLVLARHVVPASTALKAGR-WDRALYTGSELAGKTLAILGLGRVGREVATR 545
+A ELT ML R A LK R W R + G+EL K L I+G G +G V R
Sbjct: 104 AAVELTLAHMLSCVRQFPYAHNNLKLDRVWRRQDWYGTELKDKKLGIIGFGNIGSRVGKR 163
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIEST 695
AF M+++ +DP++ + + EDI D IT+HTP E T
Sbjct: 164 AKAFEMDVLAYDPYIDPSKATDLDIGYTKNFEDIL-ACDIITIHTPKTEET 213
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 116 bits (280), Expect = 4e-25
Identities = 68/173 (39%), Positives = 98/173 (56%), Gaps = 6/173 (3%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++ R+AT ++ + A LKV+ + G GV NIDV +A ++G+ V PGANA S E
Sbjct: 75 DAVISRTAT-LSAAAIAACPTLKVISKHGVGVSNIDVAAASQRGIPVYVTPGANAQSVAE 133
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
+T LM AR + L+AGRW RA G EL+G+TL +LG G+VG+ VA A G
Sbjct: 134 MTLGLMFAAARRIAWMDAELRAGRWSRA-QDGLELSGRTLGLLGFGQVGQRVARVALALG 192
Query: 561 MNIIGFDPFVSADQCAQFHCTXM------ELEDIWPLADYITLHTPLIESTRN 701
M ++ FDP CA ++++ PL+D ++LH PL TR+
Sbjct: 193 MQVVAFDPAFD-PACAPGPGAVAGVRMLGSVDELLPLSDVLSLHLPLNARTRH 244
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 116 bits (279), Expect = 6e-25
Identities = 59/135 (43%), Positives = 85/135 (62%), Gaps = 3/135 (2%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVK---LKVVGRAGAGVDNIDVDSAGKKGVGVINAPG 356
+I D +V+RSAT++ +E++D +K LK++ R G GVDNIDV A + G+ V N P
Sbjct: 38 KIKKVDCIVIRSATKIRRELIDEAIKGGKLKLIIRGGVGVDNIDVQYAEQNGIKVRNTPN 97
Query: 357 ANALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREV 536
A++ S E+ M LAR + ++ +KAG W + Y G EL GKTL I+G+GR+G E+
Sbjct: 98 ASSSSVAEIILAHMFSLARFLNQSNITMKAGLWKKKDYVGVELEGKTLGIIGMGRIGSEL 157
Query: 537 ATRMYAFGMNIIGFD 581
A + A GM II FD
Sbjct: 158 AKKCTALGMKIIYFD 172
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 116 bits (279), Expect = 6e-25
Identities = 59/172 (34%), Positives = 100/172 (58%), Gaps = 2/172 (1%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
++PN+ A+ +RS T++T +V+DA +L +G G + +D++ A K+G+ V N+P +N+
Sbjct: 137 KLPNYHAIGIRSKTKITAKVIDANPQLLAIGCFCIGTNQVDLEHAAKRGIAVFNSPFSNS 196
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
S EL ++ L+R ++ + ++AG W++ E+ GKTL I+G G +G +++
Sbjct: 197 RSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSKNCWEIRGKTLGIVGYGHIGSQLSVL 256
Query: 546 MYAFGMNIIGFD--PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
AFGM++I FD P + Q LED+ AD+ITLH P I T
Sbjct: 257 AEAFGMSVIYFDVVPIMPLGSARQVD----TLEDLLSRADFITLHVPEIPDT 304
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 116 bits (278), Expect = 7e-25
Identities = 57/167 (34%), Positives = 93/167 (55%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++VR ++T EV+ A LKV+ + G GVDNID+ +A +G+ V+ + G+N+ + E
Sbjct: 58 DAMMVRQG-RITDEVIGASPGLKVIVKHGVGVDNIDLAAAEARGIPVLRSMGSNSRAVAE 116
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L L+L + + P + A+K G W + + G + G L ++G G +GRE A A G
Sbjct: 117 HAIALALMLVKEIQPLNAAVKGGAWPKPTFIGKDFQGAMLGLVGYGGIGRETARMAEALG 176
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M ++ DP+ A +LE + P D ++LH PL +TR+
Sbjct: 177 MEVVVHDPYAPEAAEADGFAAAADLEAMLPALDILSLHCPLTSATRD 223
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 116 bits (278), Expect = 7e-25
Identities = 63/163 (38%), Positives = 94/163 (57%), Gaps = 1/163 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + L+VRS T+V KE++ GV LK++ RAG G+DNID + A K+ + ++ APGA+
Sbjct: 56 IDQYQVLIVRSRTKVDKEIIRYGVNLKIIARAGIGLDNIDTEEASKRNIKIVYAPGASTD 115
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
SA ELT L++ AR + + K G + + G ELAGKT+ I+G GR+G +VA
Sbjct: 116 SAAELTIGLLIAAARKLYDSMNMAKGGIFKK--IEGIELAGKTIGIVGFGRIGTKVAKVC 173
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLH 674
A MN+I +D ++ E LE++ +D IT H
Sbjct: 174 KALDMNVIAYDVINIKEKANIVGVRVAESLEELLKNSDVITFH 216
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 114 bits (275), Expect = 2e-24
Identities = 59/165 (35%), Positives = 93/165 (56%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
A++VR ++ V+DA L+V+ + G+G+D ID D+A +G+ V A GANA + E
Sbjct: 190 AIIVRYG-KINARVMDAAENLQVISKHGSGIDVIDQDAAAARGIAVRAAVGANAAAVAEH 248
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
L+L A+ V ++ G WD+A + EL G+TL ++GLG +GR VA AFGM
Sbjct: 249 AWALILACAKSVPQLDMRMREGHWDKATHKSVELDGRTLGLVGLGAIGRRVAAIGVAFGM 308
Query: 564 NIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
++ FDPF A T + L+ ++ +D +++H PL R
Sbjct: 309 KVLAFDPFAKE---APAGVTLVPLDTLYAESDVVSMHCPLTADNR 350
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 113 bits (273), Expect = 3e-24
Identities = 66/186 (35%), Positives = 101/186 (54%), Gaps = 14/186 (7%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
++ + DA++VRSA E+ + +GRAGAG +NI V ++G+ V NAPGANA
Sbjct: 30 DLADPDAILVRSANMHEMEI---PTSVCAIGRAGAGTNNIPVKKMSERGLPVFNAPGANA 86
Query: 366 LSACELTCRLMLVLARHVVPA-----------STALKAGRWDRALYTGSELAGKTLAILG 512
+ EL ML+ AR++VPA KA + + G EL G+TL ++G
Sbjct: 87 NAVKELVIAGMLMGARNLVPALKFVESLDGTDEAMHKATEAGKKQFAGMELPGRTLGVIG 146
Query: 513 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELE---DIWPLADYITLHTPL 683
LG +G +A GMN++G+DP ++ D + E D+ AD++TLH PL
Sbjct: 147 LGAIGSHIAEAAIRLGMNVVGYDPAITVDAAWRLPSQVKRAENVDDVLRTADFVTLHVPL 206
Query: 684 IESTRN 701
+++TRN
Sbjct: 207 LDATRN 212
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 113 bits (273), Expect = 3e-24
Identities = 59/167 (35%), Positives = 91/167 (54%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++VR ++ +++ A LKVV + GAG ++ID+ +A GV V+ A GANA S E
Sbjct: 49 DAIIVRLVERIDADLMKASPNLKVVAKHGAGTNDIDLAAAKALGVPVLAAVGANAHSVAE 108
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
LML L + V ++ G WD+ Y G EL G+ L ++G+G +GR +A + G
Sbjct: 109 HAFMLMLALIKDVRNQDAYVRGGGWDKKGYRGRELRGRVLGLVGIGMIGRALAAMVQPIG 168
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M I +DPF A L+++ +D ++LH PL T+N
Sbjct: 169 MTTIAYDPFAPAAAFGPHARRVDSLDELLAQSDVVSLHCPLTPQTQN 215
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 113 bits (273), Expect = 3e-24
Identities = 58/169 (34%), Positives = 103/169 (60%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA+++R+A ++++ V++ KLKV+ R G GVDNID+++A +G+ V NAP AN + E
Sbjct: 45 DAILIRTA-KLSRVVIEKASKLKVIARHGIGVDNIDLEAASDRGILVTNAPFANVNAVAE 103
Query: 381 LTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRM-YA 554
L+L +R ++ +AL+ G ++ R G EL GKTL ++G G +G+ VA + Y
Sbjct: 104 HVLTLILSGSRQLIQVDSALRNGDFEVRNRKFGIELKGKTLGVVGFGNIGQLVAEKCHYG 163
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
GM+++ +DP+V + + + L ++ +D +T+H P + ST +
Sbjct: 164 LGMDVLVYDPYVREENVSSYVQLNQSLSEVLASSDIVTIHVPYLPSTHH 212
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 112 bits (270), Expect = 7e-24
Identities = 61/158 (38%), Positives = 89/158 (56%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DALVV VT E L G KL+ V + G GVDNID+ + + G+ V N P ANA + E
Sbjct: 53 DALVV-GLVPVTPETLTQGGKLRAVIKHGVGVDNIDIPACTEAGLPVCNTPAANADAVAE 111
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L LM +AR + ++ AG WDR + G++L GKTL I+GLG +G+ +A G
Sbjct: 112 LAVGLMFSMARWIPQGHASVTAGGWDRRI--GTQLGGKTLGIVGLGNIGKRLAKLARGLG 169
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLH 674
M ++ D + A+ + + LE++ +DYI+LH
Sbjct: 170 MQVVATDKYPDEAFAAEHGISFLPLEELLAQSDYISLH 207
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 111 bits (268), Expect = 1e-23
Identities = 53/146 (36%), Positives = 87/146 (59%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
LK++ + G GVDNIDVD+A K GV V N P AN + + L+L LAR + + K
Sbjct: 68 LKIIAKHGVGVDNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTK 127
Query: 444 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT 623
G+W +L+ G+++ +TL I+GLG +G+EVA R F M ++ +DP++ +
Sbjct: 128 KGKWP-SLF-GADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPYIDRTYARKNGIE 185
Query: 624 XMELEDIWPLADYITLHTPLIESTRN 701
+ L+ + +D++T+H PL+ TR+
Sbjct: 186 AVSLDALLQQSDFVTIHIPLLPETRH 211
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 111 bits (268), Expect = 1e-23
Identities = 67/175 (38%), Positives = 95/175 (54%), Gaps = 3/175 (1%)
Frame = +3
Query: 186 EIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
EI N DA+ +R ++ E++ A KL++V R GAG DN+D +A + GV V N PGAN
Sbjct: 37 EIQNEVDAVFLRGG-HISAEMIAASPKLRIVARHGAGYDNVDYKAAAELGVWVTNTPGAN 95
Query: 363 ALSACELTCRLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREV 536
S E L+L ++R V A+ + W DR TG EL G+TL ++G G +GR V
Sbjct: 96 RRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSLTGIELEGRTLGLIGFGDIGRHV 155
Query: 537 ATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A AFGM ++ DP F ++L+ + AD ++LH PL E T N
Sbjct: 156 APVAEAFGMKVLATDPAYD----TSFDKRLVDLDTLLTQADVVSLHVPLQEGTEN 206
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 111 bits (267), Expect = 2e-23
Identities = 63/176 (35%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ + + L++R + + +E + LKV+GR G GVD++DV +A + G+ V+ APG+N
Sbjct: 40 ELLDAEGLIIRIGS-IDRETMLQAKNLKVIGRPGVGVDDVDVKTATELGIPVVIAPGSNT 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVAT 542
S E LM A+ +V + ++ G + R+ Y EL KTLA++G GR+G +A
Sbjct: 99 RSVAEHAFALMFACAKDIVRSDNEMRKGNFAIRSSYKAYELNHKTLALIGYGRIGSILAQ 158
Query: 543 RMYAFGMNIIGFDPFV---SADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A GMN+ +DPFV + +Q +CT EL+D+ + I++H PL TRN
Sbjct: 159 MSKAIGMNVKVYDPFVKQGTIEQEGYIYCT--ELDDVIRDSHVISIHVPLTNETRN 212
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 111 bits (267), Expect = 2e-23
Identities = 65/167 (38%), Positives = 94/167 (56%), Gaps = 1/167 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA +V S T+EVL LKV+ R G G D+ID D+A + GVG+ PG NA + +
Sbjct: 51 DAAIV-STDPFTREVLAGDRNLKVIARVGVGTDSIDHDAAKEFGVGISVTPGMNAETVAD 109
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDR-ALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
T ++L L R VV A+KAGRWDR T +EL KT+ ++G G +G+ V R+ F
Sbjct: 110 QTLAMILGLMRRVVTQDQAVKAGRWDRVGEATPTELYRKTVGLIGAGIIGKAVIRRLLGF 169
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
G+ ++ FD V A+ C L+ + +D ++LH PL+ TR
Sbjct: 170 GVRVLYFDAMVEKVHGAE-RCG--SLDQLLGSSDIVSLHAPLLADTR 213
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 111 bits (267), Expect = 2e-23
Identities = 58/170 (34%), Positives = 98/170 (57%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+P ++ LV+RS +V K+++D+ KL+ + RAGAGVDNID + +K + + +A N +
Sbjct: 42 LPAYEGLVIRSKFRVDKKIIDSCTKLQFIARAGAGVDNIDKEYLKEKNIALFHASEGNRV 101
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ E T L+L L ++V + T +K W R G EL T+ ++G G +G+E + R+
Sbjct: 102 AVGEHTLGLILALINNIVRSDTEVKDAIWLREENRGYELESLTVGLIGYGNMGKETSKRL 161
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
AFG II +D + C + +++E + AD I+LH PL + +R
Sbjct: 162 AAFGCKIIAYDKYRENYSCK--NAEQVDIEKLKAEADIISLHIPLDDFSR 209
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 111 bits (267), Expect = 2e-23
Identities = 57/169 (33%), Positives = 101/169 (59%), Gaps = 3/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ALV RS +V+ +++ +LK++ RAG+G+DN+DV+ A K+GV ++ P +A + E
Sbjct: 65 EALVFRSGIRVSADLMGCAPRLKLLVRAGSGMDNLDVEYARKRGVQLVRIPQPSARAVAE 124
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
+ ML L+R ++ A +++ GRW++ ++G L KTL ++G+G G VA A+G
Sbjct: 125 MAFAFMLALSRRLLEADRSMRNGRWEKHEFSGYLLRDKTLGVVGIGNTGSCVAQMGVAWG 184
Query: 561 MNIIGFDPFVSADQCAQF---HCTXMELEDIWPLADYITLHTPLIESTR 698
M +IG S ++ F +E + + ADY+++H PL ++TR
Sbjct: 185 MRVIGCVQHPSREREEGFCEKGIQMLEFDQVIANADYLSIHVPLKDNTR 233
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 111 bits (266), Expect = 2e-23
Identities = 53/169 (31%), Positives = 100/169 (59%), Gaps = 4/169 (2%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA+V + + KE + + K K++ G +NID+++A ++G+ V N PG + +
Sbjct: 45 DAIVTQLRDPIDKEFIYSLKKAKIIANYAVGYNNIDIEAAKERGIYVTNTPGVLTEATAD 104
Query: 381 LTCRLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILGLGRVGREVATRMY 551
+ L+L +AR +V + ++ G+ W L+ G +L GKTL ++G+GR+G+ VA R
Sbjct: 105 IAFALILAVARRIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIGMGRIGQAVARRAL 164
Query: 552 AFGMNIIGFDPFVSADQC-AQFHCTXMELEDIWPLADYITLHTPLIEST 695
FGMNI+ ++ ++ Q++ + ++++ ++DYI+LHTPL + T
Sbjct: 165 GFGMNIVYYNRNRLPEEIEKQYNAKYVNIDELVEISDYISLHTPLTKET 213
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 110 bits (264), Expect = 4e-23
Identities = 79/222 (35%), Positives = 115/222 (51%), Gaps = 52/222 (23%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNI--------------------- 305
IP ++ALVVRS T+VT +L A +LKVV RAG GVDN+
Sbjct: 46 IPEYEALVVRSETKVTANLLRAAKQLKVVARAGVGVDNVGELAQPPLPPSPSLGSWPLTS 105
Query: 306 ---DVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTG 476
DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G
Sbjct: 106 HRTDVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVG 165
Query: 477 SELAGKTLAILGL---------GR------------------VGREVATRMYAFGMNIIG 575
E+ GKTL+I+GL GR VG VA GM++
Sbjct: 166 VEVKGKTLSIIGLGKGELLAIWGRGIHFRYDGGSSGWADRQTVGLTVARLAKGLGMHVNA 225
Query: 576 FDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTR 698
DP+ S A T + L ++ P AD++T+HTPLI ST+
Sbjct: 226 LDPYASPAVAASASVTLVSSLSELLPTADFLTIHTPLIASTK 267
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 110 bits (264), Expect = 4e-23
Identities = 57/171 (33%), Positives = 100/171 (58%), Gaps = 5/171 (2%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN--IDVDSAGKKGVGVINAPGANALSAC 377
A+V R A +++ +++ LK++ R GAGVD +D+ +A ++ + + PG N+++
Sbjct: 51 AIVDRKA-KISSKIIRELRNLKLIARTGAGVDETRVDLKAAKERDIIITYNPGGNSVAVA 109
Query: 378 ELTCRLMLVLARHVVPASTALKAGRWDRAL---YTGSELAGKTLAILGLGRVGREVATRM 548
ELT L + L R V+P + ++KAG+W G EL GK ILG G +G+ VA +
Sbjct: 110 ELTIMLAIALYRKVIPLALSVKAGKWSELKPKDTMGHELEGKAWGILGFGNIGKRVAQLV 169
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ ++G+DP+VS++ + + LE++ +D I++H PL ESTR+
Sbjct: 170 TSLNCKVLGYDPYVSSEIMEKHGVKSLSLEELLSKSDIISIHVPLTESTRH 220
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 109 bits (262), Expect = 6e-23
Identities = 52/163 (31%), Positives = 86/163 (52%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
V+ + V + +LK + R G GVDNID+D+A + G+ V NAPG NA + ELT
Sbjct: 54 VIAGVDTWNERVFNLAPRLKAIARFGVGVDNIDIDAAHRHGIAVTNAPGGNANAVAELTL 113
Query: 390 RLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNI 569
L+L R + AL+ G WDR + G EL G+ + +LG G + R++A ++ F + +
Sbjct: 114 GLILSAMRRIPYLHDALRGGAWDR--FVGQELIGRRVGLLGFGNIARKIARKLCGFDVEV 171
Query: 570 IGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
I +D F + E++++ +D + + P + TR
Sbjct: 172 IAYDKFPDQVAATKLGVRMCEMDEVLSSSDILVMMMPSLPETR 214
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 109 bits (262), Expect = 6e-23
Identities = 61/159 (38%), Positives = 93/159 (58%), Gaps = 2/159 (1%)
Frame = +3
Query: 231 VTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
+T V+D + +LKV+ + G G+D IDV A K + V+ PG N + E T L+L L
Sbjct: 58 ITAAVIDKSLPRLKVISKYGIGLDKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLAL 117
Query: 408 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
++++ + + ++G W R TG EL KT+ I+GLGR+G+EVA R AFGM +I +D +
Sbjct: 118 EKNILFHTDSTRSGGWKRK--TGHELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYDIY 175
Query: 588 VSADQCAQFHCTXMEL-EDIWPLADYITLHTPLIESTRN 701
Q + + E+I+ ADYI+LHT L TR+
Sbjct: 176 WDEAFAKQHNVKRVATKEEIFTSADYISLHTNLTPETRD 214
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 109 bits (261), Expect = 9e-23
Identities = 67/172 (38%), Positives = 97/172 (56%), Gaps = 12/172 (6%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA ++RS T E L + LKV+ RAGAGV+NI +D A G V N PG+NA + E
Sbjct: 31 DAYLIRSVNLHT-ETLPSS--LKVIVRAGAGVNNIPIDQATANGTAVFNTPGSNANAVKE 87
Query: 381 LTCRLMLVLARHVVPAST---------ALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 533
L L+++ +R+++ A+T + D+ + G EL GKTLA++GLG VG
Sbjct: 88 LIIGLLIMASRNLIAATTYSAQHTEADISQRTEHDKTQFNGIELTGKTLAVIGLGHVGAL 147
Query: 534 VATRMYAFGMNIIGFDPFVSAD---QCAQFHCTXMELEDIWPLADYITLHTP 680
VA + GMN+IG+DP++SAD A+ L D AD++T+H P
Sbjct: 148 VANAALSLGMNVIGYDPYLSADAAWNIAKQVQRAATLPDAVKQADFVTVHVP 199
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 109 bits (261), Expect = 9e-23
Identities = 57/165 (34%), Positives = 91/165 (55%), Gaps = 3/165 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + DAL+ +T V KEV+DA LK++ GAG +N+D+D A ++ + V N P A+
Sbjct: 43 VKDADALISLLSTSVDKEVIDAANNLKIITNYGAGFNNVDIDYARQQNIDVTNTPKASTN 102
Query: 369 SACELTCRLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILGLGRVGREVA 539
S ELT L+L +AR + + W + G E++GKT+ I+GLG +G VA
Sbjct: 103 STAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVA 162
Query: 540 TRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLH 674
R AF MNI+ P D+ + ++LE + AD++T++
Sbjct: 163 RRAKAFDMNILYTGPHQKVDKEREIGAKYVDLETLLKNADFVTIN 207
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 109 bits (261), Expect = 9e-23
Identities = 59/160 (36%), Positives = 94/160 (58%), Gaps = 14/160 (8%)
Frame = +3
Query: 261 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTAL 440
+L +GRAGAG +NI ++ KG+ V NAPG NA + EL +M+ R++ PA+ L
Sbjct: 52 ELLAIGRAGAGFNNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWL 111
Query: 441 KAGRW-DRAL----------YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
+ D+A+ ++GSE++GKTL ++GLG +G +VA GM +IG+DP+
Sbjct: 112 TGQKGNDKAIDVAVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPY 171
Query: 588 VSADQC--AQFHCTXM-ELEDIWPLADYITLHTPLIESTR 698
+S + H + +L +I+ ADYIT+HTP + T+
Sbjct: 172 LSIEHAWNLSHHVKRVNDLSEIFEKADYITVHTPATDETK 211
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 109 bits (261), Expect = 9e-23
Identities = 62/166 (37%), Positives = 96/166 (57%), Gaps = 2/166 (1%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
LVVRS QV +V DA L +V RAGAGV+ IDV +A ++GV V N PG N+++ EL
Sbjct: 45 LVVRSK-QVQADVFDAAPGLSLVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELA 103
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSE-LAGKTLAILGLGRVGREVATRMYAFGM 563
L++ L R + L+AG+WD+ ++ ++ L G+TL + G+G +GREVA R A GM
Sbjct: 104 IGLVVALDRRIPDNVALLRAGKWDKKTFSEAQGLYGRTLGVAGVGSIGREVARRAQALGM 163
Query: 564 NIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTR 698
++ + + Q +L + +D+++LH L + TR
Sbjct: 164 RVVAWSRSLDDRQAKLLGVERAPDLAALARESDFLSLHLALSKETR 209
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 108 bits (259), Expect = 1e-22
Identities = 62/165 (37%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
ALVVR+ TQV +++++A L+V+ RAG G+DNIDV A + GV V+ GANA+S E
Sbjct: 52 ALVVRNRTQVDRQLIEACPSLRVIARAGVGLDNIDVKCANEAGVVVVAPLGANAISVAEH 111
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
T + L R V + G W+R G EL G +LG G GR A + GM
Sbjct: 112 TIGMALAAVRRTVELDADCRRGGWERT--PGRELHGGVWGLLGAGATGRACARLARSLGM 169
Query: 564 NIIGFDPFVSADQCAQFHCTXMELED-IWPLADYITLHTPLIEST 695
+I+ +DPF A++ AQ +E + AD ++ H P T
Sbjct: 170 SIVAYDPFADAEKLAQEGIELVEHPALVAARADVMSCHLPATRGT 214
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 108 bits (259), Expect = 1e-22
Identities = 61/173 (35%), Positives = 90/173 (52%), Gaps = 3/173 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+P A ++ + +D AG L + R G GVDNID+ +A ++G+ VIN P
Sbjct: 44 LPGSAAAIISAMINADGAWMDRAGPTLMAIARPGIGVDNIDLAAATERGILVINTPDGPT 103
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVA-T 542
S E L+L LA+ VV A + W A G E+ GKTL ++GLGR+GR VA
Sbjct: 104 ESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRGVEVRGKTLGVVGLGRIGRRVAQI 163
Query: 543 RMYAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTR 698
GM + +DP A+ A +E L+++ P ++++TLH L STR
Sbjct: 164 CRQGLGMRVAAYDPLAPAEAFAALDVVHVETLDNLLPQSEFLTLHCALTPSTR 216
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 107 bits (258), Expect = 2e-22
Identities = 55/160 (34%), Positives = 92/160 (57%), Gaps = 3/160 (1%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
++ +V DA KL++VG + AG++N++V A K+G+ V N G NA + + T LML
Sbjct: 85 ISSKVFDAMPKLRIVGVSRAGLENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAEC 144
Query: 411 RHVVPASTALKAGRWDRALYTGS---ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 581
R++ A ++K G W + EL GK + ++G G +GR VA ++ FG+ + +D
Sbjct: 145 RNIARAHYSIKNGGWRKEFSNSDWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVYD 204
Query: 582 PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
PFV + C ++ E ++ +D+I+LH L EST+N
Sbjct: 205 PFVDEETIRGAGCIPVDKETLFKESDFISLHARLSESTKN 244
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 107 bits (258), Expect = 2e-22
Identities = 62/166 (37%), Positives = 92/166 (55%), Gaps = 3/166 (1%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
L VR Q+T +VLDA +L V +G GVDNID+ +A + GV V N PG E
Sbjct: 47 LAVRYPAQITADVLDAAPQLLAVLSSGRGVDNIDIPAASRAGVVVANNPGLGGKPVSEHA 106
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGS-ELAGKTLAILGLGRVGREVATRMYA-FG 560
L++++ R + + G W++ L T EL G TL I+G G VG +A R A F
Sbjct: 107 LGLLIMITRDLTAVARDAMTGAWEKRLTTRRVELTGGTLGIVGCGNVGGWMARRASAGFQ 166
Query: 561 MNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIEST 695
M ++ +DP+VSA+Q AQ T ++ L+ + AD+++ H L + T
Sbjct: 167 MRVLAYDPYVSAEQMAQVGATKVDNLDKLLAEADFVSCHPELNDET 212
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 107 bits (256), Expect = 3e-22
Identities = 58/167 (34%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DAL+V + TQVT EV++A LKVVGRAG G+DNI V +A GV V+N P +
Sbjct: 48 DALIVDAGTQVTAEVIEAADSLKVVGRAGIGMDNIAVRAAVAAGVTVVNVPDYSVEEVST 107
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRAL-YTGSELAGKTLAILGLGRVGREVATRMYAF 557
T LML R + ++K G W A+ LAG T+ ++ G++ A ++ F
Sbjct: 108 HTFALMLACLRRIPTFDRSVKRGEWKWAVGQPIRRLAGSTVGLVAFGKLASRFAAKLRGF 167
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
+++I +DP+ + + LE + +D ++LH PL + TR
Sbjct: 168 DIDVIAYDPYAPEYRMGDLGVESVTLETLLGDSDIVSLHAPLTDETR 214
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 106 bits (254), Expect = 6e-22
Identities = 58/173 (33%), Positives = 94/173 (54%), Gaps = 4/173 (2%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + D L++ +TQV ++VLD LK++ GAG +NID+ +A K+ + V N P +A+
Sbjct: 43 VADADFLIIPLSTQVDQDVLDHAPHLKLIANFGAGTNNIDIAAAAKRQIPVTNTPNVSAV 102
Query: 369 SACELTCRLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILGLGRVGREVA 539
+ E T L++ LA +V ++ W + G L GKTL ILGLG++G+ VA
Sbjct: 103 ATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLFFLGHNLQGKTLGILGLGQIGQAVA 162
Query: 540 TRMYAFGMNIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
R++AF M I+ + + Q T + +++ AD +TLH PL T
Sbjct: 163 KRLHAFDMPILYSQHHRLPISRETQLGATFVSQDELLQRADIVTLHLPLTTQT 215
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 106 bits (254), Expect = 6e-22
Identities = 58/167 (34%), Positives = 92/167 (55%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++ R+ + +++ L+V+ R G G +N+D++SA ++GV V+ A GAN S E
Sbjct: 48 DAVISRTLA-LPAMMIETAPALRVISRHGVGYNNVDIESATRRGVPVLIADGANGKSVAE 106
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L L L +AR + +++A +W+R+ Y G + AGKT I+ G +GR VA + A
Sbjct: 107 LAVGLALSVARKITTQDASIRARQWNRSAY-GLQFAGKTAGIVAFGAIGRRVAEILRAMD 165
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M II FDP T L+++ +D ++LH PL TRN
Sbjct: 166 MRIIAFDPHARDRSTTGVDWTE-TLDELLQESDLVSLHCPLTPETRN 211
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 105 bits (253), Expect = 8e-22
Identities = 56/170 (32%), Positives = 92/170 (54%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
++ +DA V+ A ++EVL LKV+ R G G D +D+ +A + + V PG N
Sbjct: 46 QVQGYDA-VLAGAEIYSREVLQQLPDLKVISRYGVGFDAVDLAAADAQNIVVTITPGVNH 104
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
S E L++ +AR A+++G W+R L + G T+ I+GLGR+G+ VATR
Sbjct: 105 HSVAEQAFALLMGIARMTRTQDRAVRSGEWERELTP--RVWGSTIGIVGLGRIGQAVATR 162
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
GM+++ +DPF + + + LE++ +DY+TLH P+ T
Sbjct: 163 AIGMGMHVLAYDPFPNEEFAKTHQIKLLSLEELLKQSDYVTLHLPVTPET 212
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 105 bits (252), Expect = 1e-21
Identities = 59/158 (37%), Positives = 89/158 (56%), Gaps = 13/158 (8%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
+K V RAGAGV+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K
Sbjct: 50 VKAVARAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVK 109
Query: 444 AGRWD----------RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS 593
+ + + G+ELAGK L I+GLG +G VA + GM+++G+DPFVS
Sbjct: 110 ELPAEDDVEQKVEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVS 169
Query: 594 ADQCAQFHC---TXMELEDIWPLADYITLHTPLIESTR 698
D + M +E++ DY+T+H PL + TR
Sbjct: 170 VDTAWRISKEVERAMTIEEVLATCDYLTVHVPLTDKTR 207
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 105 bits (252), Expect = 1e-21
Identities = 57/167 (34%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D ++VR+ TQV + LDA +L+V+G G G+DNID+ + +G+ V A GAN S E
Sbjct: 46 DGVIVRNRTQVDRPFLDAASRLRVIGLLGTGLDNIDMAACAARGISVHPATGANTRSVAE 105
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGREVATRMYAF 557
L+L R ++ ++ G W R L G E+AG+ L + G G V + VA
Sbjct: 106 YVITAALMLTRRAFMSTPEMQEGAWPRGPLGEGGEIAGRKLGLYGCGAVAQAVARLAKPL 165
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
M I+G DP + T + ++ AD ++LH PL TR
Sbjct: 166 SMTILGHDPHLGPGHPLWTEVTRVSDAELLARADVLSLHLPLTPETR 212
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 105 bits (252), Expect = 1e-21
Identities = 53/151 (35%), Positives = 87/151 (57%)
Frame = +3
Query: 228 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
+++ +VL+ +LK + R G GVD+IDV++A + G+ V+ APGAN+ ELT L+L
Sbjct: 72 RLSGQVLEDLTRLKAISRNGVGVDSIDVEAAERLGINVLTAPGANSQGVAELTIALILAG 131
Query: 408 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
+R + LK+G+W+R G+E++GK L ++G G++GR VAT GM +I FD +
Sbjct: 132 SRSIPWHDAQLKSGQWNRR--PGNEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEY 189
Query: 588 VSADQCAQFHCTXMELEDIWPLADYITLHTP 680
+ E + + ++LHTP
Sbjct: 190 PVTSFAPSPDFSWAPRERVLSSSHVVSLHTP 220
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 105 bits (251), Expect = 1e-21
Identities = 59/152 (38%), Positives = 83/152 (54%), Gaps = 2/152 (1%)
Frame = +3
Query: 252 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPAS 431
AG L+ + R G GVDNID+ +A K+G+ VIN P S E L+L LA+ VV +
Sbjct: 65 AGDALRAICRPGIGVDNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASD 124
Query: 432 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCA 608
L+ W A G E+ GKTL I+GLGR+GR VA GM+++ +DP V + A
Sbjct: 125 RVLRTEGWRAARLRGIEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDPPVPDETFA 184
Query: 609 QFH-CTXMELEDIWPLADYITLHTPLIESTRN 701
L+D+ P A +++LH L TR+
Sbjct: 185 TLDVARAATLDDLLPHAQFLSLHCALTPETRH 216
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 104 bits (250), Expect = 2e-21
Identities = 56/175 (32%), Positives = 97/175 (55%), Gaps = 2/175 (1%)
Frame = +3
Query: 183 MEIPNHDALVVRSATQ-VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA 359
M+ +A V TQ +++DA LKV+ R G G D +DVD+A ++G+ V+N P A
Sbjct: 37 MKAEGVEASAVLIGTQKFDADIMDAMPNLKVIARNGVGYDAVDVDAATQRGIYVVNTPKA 96
Query: 360 NALSACELTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREV 536
+ S E +L +++++ S A+ W+ R + G ++ GKT+ ILG GR+G++V
Sbjct: 97 LSGSVAETAVSELLAISKNLYQDSKAIHDDNWNYRKAHPGRDIEGKTVGILGFGRIGQQV 156
Query: 537 ATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A ++ F + +I FDPF + ++ E I+ ADY+ +H P + T++
Sbjct: 157 AKKLSGFDVKVIAFDPFAKDVPGVEL----VDRETIFKTADYVMVHLPALPETQH 207
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 104 bits (250), Expect = 2e-21
Identities = 58/161 (36%), Positives = 89/161 (55%), Gaps = 3/161 (1%)
Frame = +3
Query: 228 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
++T+E++ KLK++ + G GVDNID+ +A G+ V N PG NA S ELT +++ L
Sbjct: 55 KITQELIQKAPKLKMIQKTGVGVDNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINL 114
Query: 408 ARHVVPASTALKAGRWDRALYTGS--ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 581
R + K G W + S E+ GKT I+G G +GREVA AFG N+I +D
Sbjct: 115 YRKINILDRETKKGNWMSWEFRPSSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIYYD 174
Query: 582 -PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ + + + T EL ++ +D I++H PL T+N
Sbjct: 175 LRRLEPAEEKRLNVTYHELNELLQKSDIISIHLPLTPDTKN 215
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 104 bits (250), Expect = 2e-21
Identities = 55/166 (33%), Positives = 95/166 (57%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I ++D ++VRS T++ ++++D +LK++ RAG G D+IDVD A +KG+ ++ APG++
Sbjct: 39 KIGDYDIIIVRSRTKIDRDIIDNAKRLKIIARAGIGTDSIDVDYAQEKGIKIVYAPGSST 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
S ELT ++ AR ++ + D G EL+GKTL I+G GR+GR +A
Sbjct: 99 ESVVELTVAFAVIAARQIIKGVENTRKN--DFTKLKGIELSGKTLGIIGYGRIGRAIANA 156
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPL 683
F + I +D + A+ + LED+ +D I+++ L
Sbjct: 157 FSVFNVRSIAYDAYPVDFTGAE----QVTLEDLLRNSDIISINITL 198
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 104 bits (249), Expect = 2e-21
Identities = 52/167 (31%), Positives = 95/167 (56%), Gaps = 4/167 (2%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
++ ++ EV+ K K++ R G GV+ +DVD+A +KG+ V N + +
Sbjct: 51 IINQYAPISAEVIAQLEKCKIISRYGVGVNTVDVDAATEKGIIVANVTDYSIDEVSDHAL 110
Query: 390 RLMLVLARHVVPASTALKAGRWD----RALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
L+L LAR +V + +K+G W+ + +Y L G+TL ++GLGR+ + +A + AF
Sbjct: 111 ALLLSLARKIVKLNHEVKSGTWNFNVGKPIY---RLRGRTLGLVGLGRIPQALAKKAQAF 167
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
G+ +I +DP+V A + + + L D++ +DYI++H PL + T+
Sbjct: 168 GLRVIAYDPYVPAKVADELNVQLLGLNDVFRQSDYISVHAPLTKETK 214
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 103 bits (247), Expect = 4e-21
Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 14/186 (7%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I D ++VRS E+ ++ + +GRAGAG +NI V+ +G+ V N PGANA
Sbjct: 35 DITGPDVILVRSHNLHDMEIPESVI---AIGRAGAGTNNIPVNQMSARGIPVFNTPGANA 91
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWD-----------RALYTGSELAGKTLAILG 512
+ EL ML+ +R+++PA ++ D + ++G EL G+TL ++G
Sbjct: 92 NAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNLQVEAGKKQFSGLELPGRTLGVIG 151
Query: 513 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXM---ELEDIWPLADYITLHTPL 683
LG++GR+VA GM ++G+DP ++ D ++ED+ + +I+LH PL
Sbjct: 152 LGKIGRQVADIAIKLGMKVLGYDPKITIDSAWSLPAEVQKANQIEDLIRRSQFISLHVPL 211
Query: 684 IESTRN 701
+STR+
Sbjct: 212 NDSTRH 217
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 103 bits (247), Expect = 4e-21
Identities = 56/164 (34%), Positives = 91/164 (55%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
++ +++EV+D LKV+ + G G+DNIDVD A K + V A AN++S E+T
Sbjct: 53 IITGNDPLSREVIDQAKNLKVISKYGVGLDNIDVDYANSKDIVVHKALNANSISVAEMTI 112
Query: 390 RLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNI 569
+ML +R V + + G+ R + G EL K L ++GLG +G+ VA ++ GM I
Sbjct: 113 LMMLSSSRKYVEIESQARNGKDIRLV--GYELYQKNLGLIGLGAIGQHVAHIAHSMGMTI 170
Query: 570 IGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
DP + + + ++I+ +D I+LH PL++STRN
Sbjct: 171 TAHDPHIDKSKVPSY-IELKSPDEIYQYSDVISLHLPLLDSTRN 213
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 103 bits (247), Expect = 4e-21
Identities = 59/167 (35%), Positives = 95/167 (56%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DAL+V + +V +V+ +LK++ + G GVD+IDV +A + G+ V NAPG N+ +
Sbjct: 53 DALIVGN-DKVPGDVIKKCKRLKIIAKHGVGVDSIDVKTANQLGIVVTNAPGTNSEEVAD 111
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L L+ +LAR + A+T K G+W + + G L+ KT+ I+G+G +G VA R +
Sbjct: 112 LAFGLLHMLARGLYQANTDTKNGKWIKPV--GISLSKKTIGIIGVGTIGTAVAKRATGYD 169
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
MNI+G+D + L+++ AD+I+LH PL T N
Sbjct: 170 MNILGYD-IKKNPLALGLGVKYVGLDELLSEADFISLHLPLTNDTLN 215
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 103 bits (247), Expect = 4e-21
Identities = 55/167 (32%), Positives = 90/167 (53%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ L V T+V + VL +L++V AG D+ID+++ K+G+ V + P + S E
Sbjct: 51 EVLCVFVRTRVDESVLRMLPRLRLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAE 110
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L+L + RH+ A + G + TG EL G+TL I+GLGR+GR VA FG
Sbjct: 111 HAFALLLGVTRHLTQAHERARQGSFAYRGLTGFELEGRTLGIVGLGRIGRHVARIAVGFG 170
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
M+++ +DP +A + + E + +D ++LH P E+TR+
Sbjct: 171 MDVLAYDPAFAASAARPAGVSLVTWEQVLQGSDILSLHVPATEATRH 217
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 103 bits (246), Expect = 6e-21
Identities = 61/181 (33%), Positives = 99/181 (54%), Gaps = 13/181 (7%)
Frame = +3
Query: 195 NH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALS 371
NH D +++RS + +E LK + RAGAGV+NI V+ +KG+ V N PGANA +
Sbjct: 30 NHPDGILLRSYSLHQEEF---SKDLKAIARAGAGVNNIPVERCTEKGIVVFNTPGANANA 86
Query: 372 ACELTCRLMLVLARHVVPASTALKAGRWD---------RALYTGSELAGKTLAILGLGRV 524
EL +++ +R+++ + K + + + GSE+AGK L ++GLG +
Sbjct: 87 VKELIIASLIMSSRNIINGVSWTKNLEGEEVPQLVESGKKQFVGSEIAGKRLGVIGLGAI 146
Query: 525 GREVATRMYAFGMNIIGFDPFVSADQCAQFHC---TXMELEDIWPLADYITLHTPLIEST 695
G VA A GM+++G+DP++S + + L++I+ DYITLH PL T
Sbjct: 147 GALVANDALALGMDVVGYDPYISVETAWRLSTHVQRAFSLDEIFATCDYITLHIPLTNQT 206
Query: 696 R 698
+
Sbjct: 207 K 207
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 103 bits (246), Expect = 6e-21
Identities = 64/177 (36%), Positives = 97/177 (54%), Gaps = 6/177 (3%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + LVVRS T V V++A L++V RAG+G + ID +SA ++GV V N PG NA+
Sbjct: 39 LTGREVLVVRS-TAVPSAVIEAADSLRLVIRAGSGTNTIDCESAAERGVHVCNVPGRNAI 97
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSE-LAGKTLAILGLGRVGREVATR 545
+ EL LML L R V L+AGRWD+ Y+ + + G+ + ++GLG++G A R
Sbjct: 98 AVAELAFALMLALDRSVCDNVDDLRAGRWDKKRYSRARGIHGRRVGVVGLGQIGLAFAER 157
Query: 546 MYAFGMNIIGF-DPFVSADQCAQFHCTXME-LEDIWPLA---DYITLHTPLIESTRN 701
AFG + P S + + ++D+ LA D ++LH P +TRN
Sbjct: 158 AAAFGATVHAVAKPGRSPKTAERADAIGIRFVDDLTTLARTCDVLSLHVPATSATRN 214
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 103 bits (246), Expect = 6e-21
Identities = 56/169 (33%), Positives = 96/169 (56%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D +++R+ VT+ ++++ +LKV+GR G G+D ID+ A ++GV V+ P AN S E
Sbjct: 46 DGIIIRANGAVTRALIESAPRLKVIGRHGVGLDAIDLRCAKERGVKVVFTPTANTESVAE 105
Query: 381 LTCRLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGRVGREVA-TRMYA 554
+ ++LA+ + AL+ G W R G+EL GK L +LG GR+GR+ A
Sbjct: 106 HFVGMAIMLAKMIRTGDIALRTGDWAARNRLIGTELHGKALGVLGFGRIGRQTARICRNG 165
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
F MN+I +D + + E+++ +D+I+++ PL+ STR+
Sbjct: 166 FAMNVIYYDVCDYPAVEKELQAKRVSGEEVFEQSDFISVNLPLLPSTRH 214
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 103 bits (246), Expect = 6e-21
Identities = 59/165 (35%), Positives = 87/165 (52%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
ALV+R + V+ VL A L++V + GAGVD++D+++A +GV V A ANA + E
Sbjct: 55 ALVLRGSKPVSAAVLRAAPALRIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPAVAEH 114
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
LML L R + ++AG W + + G + G T+ I+G G +GR A A G
Sbjct: 115 ALALMLALVRQLPQLDQQVRAGGWAGSNWQGRDFRGSTVGIVGYGAIGRATAQLAAALGA 174
Query: 564 NIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
++ P A Q F C +L + P D ++LH PL E TR
Sbjct: 175 KVLVLRP---AGQADDFDCEP-DLRRLLPRVDILSLHCPLTEQTR 215
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 102 bits (245), Expect = 7e-21
Identities = 65/171 (38%), Positives = 98/171 (57%), Gaps = 6/171 (3%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN--APGANALSACE 380
+++ VT E + A +L+++ A G D +D+D+A +G+ V N + GA + E
Sbjct: 52 VIITGLGPVTAEHIAAAPELQLIQCASHGFDYVDLDAARARGLPVCNIGSSGAEQQNVAE 111
Query: 381 LTCRLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVATRMYA 554
T LML LA+ +VPA TAL W R + +EL+GKTL I+GLG +G EVA R A
Sbjct: 112 QTFALMLALAKQLVPAHTALVDADWALPRLQRSITELSGKTLGIVGLGHIGEEVARRAVA 171
Query: 555 FGMNII-GFDPFVSADQCAQF-HCTXMELEDIWPLADYITLHTPLIESTRN 701
F M I+ V A++ A+ + L+++ ADY+TLH PL E+TR+
Sbjct: 172 FDMRIVYAGRERVGAEREARLGGARHVGLDELLRTADYVTLHAPLTEATRH 222
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 102 bits (245), Expect = 7e-21
Identities = 56/151 (37%), Positives = 85/151 (56%), Gaps = 2/151 (1%)
Frame = +3
Query: 234 TKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLAR 413
TKEV DA LKV+GR G G DNID+ A +G+ V P ANA S E T L+L A+
Sbjct: 55 TKEVFDAAPHLKVIGRHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAK 114
Query: 414 HVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATR-MYAFGMNIIGFDPF 587
++V A L+ G ++ R G ++ GKTL I+G GR+G+ VA + GM I+ +
Sbjct: 115 NIVIADKELRQGNYEIRNQMPGIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAYGRG 174
Query: 588 VSADQCAQFHCTXMELEDIWPLADYITLHTP 680
+ + + E++++ +D+I+LH P
Sbjct: 175 LEIKEVPDYVTIIKEVDELIRQSDFISLHMP 205
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 101 bits (243), Expect = 1e-20
Identities = 54/172 (31%), Positives = 88/172 (51%), Gaps = 7/172 (4%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DALV + ++ KEV + KL++V G DNID++ A K+G+ V N P + +
Sbjct: 47 DALVTMLSERIDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATAD 106
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDR-------ALYTGSELAGKTLAILGLGRVGREVA 539
L L+L ARHVV +++G W + + G ++ GKT+ I+GLGR+G+ +A
Sbjct: 107 LAFALLLATARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIA 166
Query: 540 TRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
R F M I+ + + + + LED+ +D++ L PL T
Sbjct: 167 KRAKGFNMRILYYSRTRKEEVERELNAEFKPLEDLLRESDFVVLAVPLTRET 218
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 101 bits (242), Expect = 2e-20
Identities = 65/186 (34%), Positives = 98/186 (52%), Gaps = 14/186 (7%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E DA++VRS K++ D +++V+GRAG GV+NI V GV V+N PGANA
Sbjct: 29 ECEEPDAILVRSCNLHDKKIAD---RVQVIGRAGVGVNNIPVRPLTLSGVPVLNTPGANA 85
Query: 366 LSACELTCRLMLVLARHVVPA-----------STALKAGRWDRALYTGSELAGKTLAILG 512
+ EL +L+ +RH+ PA T ++ ++G EL GKTL I+G
Sbjct: 86 NAVKELVITGILLASRHIYPALDYARHIEGDDETITHQVEKNKKRFSGFELPGKTLGIIG 145
Query: 513 LGRVGREVATRMYAFGMNIIGFDPFV---SADQCAQFHCTXMELEDIWPLADYITLHTPL 683
LG++G +VA GM IG+DP + SA + + L D+ +D++T+H PL
Sbjct: 146 LGQIGVKVANAAIRLGMKAIGYDPAITVRSAWELSSEVAQAESLRDVLRNSDFVTVHVPL 205
Query: 684 IESTRN 701
T +
Sbjct: 206 NTHTHH 211
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 100 bits (240), Expect = 3e-20
Identities = 54/170 (31%), Positives = 97/170 (57%), Gaps = 1/170 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ ++ L+VRS T + ++++ +LKV+ RAGAG+D ID+ +A +G+ V+NAP N
Sbjct: 41 VDKYEGLMVRSKTAIDEDLIGRASRLKVIARAGAGLDKIDLSAANARGIKVLNAPEGNRD 100
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ E T ++L L +V A +K W R G EL K + ++G G +G+ A R+
Sbjct: 101 AVGEQTIGMLLSLLHNVQRADWEVKNFAWKREANRGVELMDKVVGVIGYGNMGKAFAKRL 160
Query: 549 YAFG-MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+FG ++I +D D+ ++ + +++++ A+ I+LH PL E T
Sbjct: 161 SSFGCKDVIAYDR--RPDRGDEY-ARQVSMDEVFERAEIISLHVPLDEYT 207
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 99 bits (238), Expect = 5e-20
Identities = 57/167 (34%), Positives = 92/167 (55%), Gaps = 3/167 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + DA + R+A T+ + +AG +L+V+G G G + ID+ +A + G+ V+N PGANA
Sbjct: 44 IADCDAAITRNAGLDTRAI-EAGRRLRVIGNHGTGTNMIDLAAAERLGIPVVNTPGANAR 102
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTG-SELAGKTLAILGLGRVGREVAT- 542
S EL + + L + VP A++ G W+ G EL+G +L I+G G++GR +A
Sbjct: 103 SVAELALAMAMALLKRTVPLDQAVRQGNWNIRYEAGLRELSGMSLGIVGFGQIGRALAAM 162
Query: 543 RMYAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTP 680
+ FGM + + P V+ A C + L + AD ++LH P
Sbjct: 163 AIGGFGMRVHVYSPSVAPQDIAAAGCQRADSLPALAREADIVSLHRP 209
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 99 bits (238), Expect = 5e-20
Identities = 55/172 (31%), Positives = 99/172 (57%), Gaps = 2/172 (1%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ + DA++VR A +T++V+ AG KLKV+ R G GV+N+D+ +A + + + NAP +N
Sbjct: 40 EVKDCDAILVRMAN-ITEKVIRAGKKLKVISRFGVGVNNVDIKTASELSIQITNAPESNK 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
+ E T L++ LA+ L+ G + G +L GK L I+GLG +G+ +A +
Sbjct: 99 NTVAEYTMGLIIALAKKFFLYDRGLRKGNFKVRDILGIDLEGKVLGIVGLGSIGKLLALK 158
Query: 546 -MYAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIEST 695
FGM +IGF + + + + + L+ + +D+++L+ PL ++T
Sbjct: 159 ASKGFGMKVIGFKRHIDEESKSLDYVELTDSLDYVLENSDFVSLNVPLTKAT 210
>UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: D-3-phosphoglycerate
dehydrogenase - Microscilla marina ATCC 23134
Length = 322
Score = 99 bits (238), Expect = 5e-20
Identities = 61/170 (35%), Positives = 92/170 (54%), Gaps = 6/170 (3%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVK--LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
+V A + +E++DAG++ L+ + +AG G+DNID + A + + V N P + E
Sbjct: 52 IVSGAAPIGREIMDAGLQKGLRGIVKAGTGLDNIDCEYARCQQILVENIPDYVHETVAEY 111
Query: 384 TCRLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVA-TRMYA 554
LML LAR P ++ W G+EL GKT+ ++G GR+ R VA +
Sbjct: 112 AINLMLSLARKSWPVQQTMRQKGWFDITPASLGTELNGKTIGLVGFGRIARSVARIAHFG 171
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
F M++I +DP+VSA++ E LEDI P D ++LHT L TRN
Sbjct: 172 FQMSVIAYDPYVSAEEMELCAVQKAEQLEDILPHCDVVSLHTSLNNDTRN 221
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 99.5 bits (237), Expect = 7e-20
Identities = 59/181 (32%), Positives = 99/181 (54%), Gaps = 9/181 (4%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I DA++ + + E++ G LKV+G+ AG +NID+D+A + GV V + PG
Sbjct: 39 QIATADAILTSLSDPLDAEMIGQGKNLKVIGQCAAGFNNIDLDAAKQAGVVVTSTPGVLH 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGLGRVGREV 536
+ +L L+L + R A ++AG R+D G+ L G TL I+GLG++G +
Sbjct: 99 EATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTFMLGAGLQGATLGIVGLGQIGEAM 158
Query: 537 ATRMYAFGMNII---GFDPFVSADQCAQFH---CTXMELEDIWPLADYITLHTPLIESTR 698
A R AFGMN+I + V+A + +EL++++ +D ++LH PL + TR
Sbjct: 159 ARRGAAFGMNVIYNARHEKDVAAIDAVNLNTQPTRRVELDELFATSDVVSLHCPLTDETR 218
Query: 699 N 701
+
Sbjct: 219 H 219
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 99.5 bits (237), Expect = 7e-20
Identities = 63/173 (36%), Positives = 89/173 (51%), Gaps = 15/173 (8%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
L+VRSATQV K+++D LK++GR G G+DNIDV A +KG+ VIN P A++ S EL
Sbjct: 59 LLVRSATQVRKDIIDNCPSLKLIGRGGVGMDNIDVAYAKEKGLHVINTPAASSESVAELV 118
Query: 387 CRLM------LVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ L A +P K + ++ GSEL GKTL ++G GR+G+ A
Sbjct: 119 FAHLFGGVRFLYDANRNMPLEGDSKFKQLKKSYAGGSELRGKTLGVIGFGRIGQATAKIA 178
Query: 549 YAFGMNIIGFDPFVSA---------DQCAQFHCTXMELEDIWPLADYITLHTP 680
GM +I DPF+ Q F ++ AD+I+LH P
Sbjct: 179 LGIGMKVIYSDPFIEKASIELPFFDGQKVSFDFVSKSKSELLQNADFISLHVP 231
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 99.5 bits (237), Expect = 7e-20
Identities = 54/162 (33%), Positives = 86/162 (53%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
V+ S T EVL +++VV R G G D+++V +A ++ + V PG S E T
Sbjct: 49 VICSTEPYTAEVLSR-TQVRVVSRVGVGYDSVNVPAATEQNIAVCRTPGTLHQSVVEHTI 107
Query: 390 RLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNI 569
++L + R+V+ + ++AG WDR G GKTL I+G G +G+EVA GM +
Sbjct: 108 GMILAIYRNVISQNKQVRAGDWDRT--AGPRAYGKTLGIIGYGVIGKEVAKAAVLLGMQV 165
Query: 570 IGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
I +DP A ++ + L++IW +D ++LH P T
Sbjct: 166 IAYDPIAPAGGPSEVE--RVALDEIWRRSDVVSLHAPCTPET 205
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 99.1 bits (236), Expect = 9e-20
Identities = 54/166 (32%), Positives = 89/166 (53%), Gaps = 2/166 (1%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
L +RS TQVT+ +LDA KL +G G + +D+D A +GV V N+P AN S EL
Sbjct: 158 LGIRSKTQVTQAILDAAPKLLGIGCFCIGTNQVDLDYATTRGVAVFNSPFANTRSVAELV 217
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
++ L+R + S + G W++ E+ GKT+ I+G G +G +V A GMN
Sbjct: 218 IGEIISLSRKMTQRSEEVHRGVWNKTHVGCYEVRGKTVGIVGYGHIGSQVGVLAEALGMN 277
Query: 567 IIGFD--PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
++ +D P ++ +F + D+ +D++T+H P + T+
Sbjct: 278 VVFYDVLPTLAIGNATKF----THINDLLTFSDFVTIHVPETDVTK 319
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/173 (35%), Positives = 92/173 (53%), Gaps = 2/173 (1%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+IP D ++VR + ++ V DA KLKV+ R G+G D +D+ +A K GV V+NAP AN+
Sbjct: 60 DIPECDGIIVR-LSPMSARVFDAAKKLKVLVRHGSGYDTVDLAAAKKHGVTVLNAPLANS 118
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYT-GSELAGKTLAILGLGRVGREVAT 542
S EL ML +R+ + + L T SE+A K L ++G+G +G VA
Sbjct: 119 TSVAELALFYMLHCSRNFRLVQQTMLVDYYKAKLDTPKSEIACKKLGLIGVGNIGSRVAK 178
Query: 543 RMYAFGMNIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
F M +IGFDP+ AD T + + I+ D+++LH P T+
Sbjct: 179 MARGFDMQVIGFDPYKTQADMPEGVELT-QDFDRIFTDCDFVSLHCPSTPETK 230
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 98.3 bits (234), Expect = 2e-19
Identities = 52/177 (29%), Positives = 93/177 (52%), Gaps = 5/177 (2%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
++ + DA++ + E++ G KLKV+ GAG D +DV +A ++ + V N PGA
Sbjct: 19 KVTDVDAIICHGKDKADAELVAKGSKLKVISNFGAGYDTVDVKAATERNIWVCNTPGAVT 78
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDR-----ALYTGSELAGKTLAILGLGRVGR 530
+ ++ L+L R A L+ G W+R + G+ GKTL I+G+G +G+
Sbjct: 79 NATADVALYLLLAACRRATEAERFLRDGSWERQGSDILAFWGNNPEGKTLGIIGMGNIGK 138
Query: 531 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+A R A M +I + + + T ++D+ +D+I++HTPL ++TR+
Sbjct: 139 ALAKRAAALDMRVIYYKR-TPLPKEEENGATYKSMDDLLAESDFISIHTPLTDATRH 194
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 97.9 bits (233), Expect = 2e-19
Identities = 50/159 (31%), Positives = 84/159 (52%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+++ + Q+ KE++DA LK + + GAG DNID A +KG+ V N PG NA + +L
Sbjct: 51 VIITAVVQIDKEIIDAAPNLKYIMKFGAGYDNIDFKYAREKGIPVTNTPGQNADAVADLA 110
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
LML AR++ + L+ G W+ L G E+ K L I+G G +G+ +A R F M
Sbjct: 111 IGLMLATARNIPAKNEELRNGNWE--LSMGIEIFQKKLGIIGFGAIGQAIAQRATGFQME 168
Query: 567 IIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPL 683
++ + F + + ++L + +D + + T L
Sbjct: 169 VLAYGTFQDQTIADRLNVEFVDLNKLLNESDIVVVSTTL 207
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 97.9 bits (233), Expect = 2e-19
Identities = 55/157 (35%), Positives = 88/157 (56%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
VT++VL A +LKV+ R G G D +DVD+A G V A GAN + + T LML +
Sbjct: 94 VTRDVLAAHPQLKVIARRGVGYDRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVL 153
Query: 411 RHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV 590
R + + A+ G W R L G++L GKT+ ++G GR+GR+VA R+ F + ++
Sbjct: 154 RRLKASQAAIARGDW-RVL-VGADLTGKTVGLIGFGRIGRQVARRLSGFDVTVLVTSRTP 211
Query: 591 SADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ T + L+++ +D ++LH PL+ TR+
Sbjct: 212 DPEAAG---VTFVALDELIARSDVVSLHAPLVPETRH 245
>UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter
ATP-binding subunit; n=4; Bacteria|Rep:
Spermidine/putrescine ABC transporter ATP-binding
subunit - marine gamma proteobacterium HTCC2080
Length = 395
Score = 97.9 bits (233), Expect = 2e-19
Identities = 63/188 (33%), Positives = 100/188 (53%), Gaps = 16/188 (8%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
EI + DA+++RS E+ + + RAGAGV+NI + + G+ V N PGANA
Sbjct: 28 EIGSADAMLLRSHKLQADEI---SASVTAIARAGAGVNNIPLSHCTELGIPVFNTPGANA 84
Query: 366 LSACELTCRLMLVLARHV---VPASTALKAGRWDRAL----------YTGSELAGKTLAI 506
+ EL +L+ +R + + +L ++A+ + G+EL GKTL +
Sbjct: 85 NAVKELVAAGLLLASRDILGGIDFVNSLSEDLDEQAMGPLLEAEKKRFAGAELKGKTLGV 144
Query: 507 LGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPL---ADYITLHT 677
LGLG +G VA GM+++GFDP +S + Q + +E++ L ADYI++H
Sbjct: 145 LGLGAIGSLVAQLGLELGMDVVGFDPAISIEAAWQLPSSVKRMENMQALFSRADYISIHV 204
Query: 678 PLIESTRN 701
P IEST +
Sbjct: 205 PAIESTHH 212
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 97.5 bits (232), Expect = 3e-19
Identities = 50/163 (30%), Positives = 84/163 (51%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+V+RS ++ E L + +L+ + R GAG++NID+ SA K V +NAP N + E
Sbjct: 48 VVIRSKIKIDAEFLSSATQLRFIARVGAGMENIDIQSADKHQVVCLNAPEGNRDAVAEQA 107
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
++L L ++ A ++ G W R G EL GKT+ I+G G G A ++ F +
Sbjct: 108 VGMILTLFNRLLIADAEVRKGIWLREQNRGIELGGKTVGIIGYGNTGSAFARKLQGFDVR 167
Query: 567 IIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
I+ +D + + +++I+ AD ++ H PL E T
Sbjct: 168 ILAYDKYKTG--FGNSFVKEATMDEIYQQADILSFHVPLTEET 208
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 97.5 bits (232), Expect = 3e-19
Identities = 56/159 (35%), Positives = 88/159 (55%), Gaps = 3/159 (1%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
+T+E++ A K+K++ + G +NIDV++A K + V N G NALS E T L L
Sbjct: 60 ITEEMMRAMEKVKLIQQPSTGYNNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALL 119
Query: 411 RHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 581
R ++ A ++ +GRW++ A EL GKT I+G+G GREV R+ +G+ II D
Sbjct: 120 RRLIYAHNSVLSGRWEQDEMANLGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD 179
Query: 582 PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
A+ ++ + + + AD ++LH PL E TR
Sbjct: 180 -VRRAEDIEEYGVEFRDFDALLREADIVSLHVPLTEETR 217
>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=8; Yersinia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 316
Score = 97.1 bits (231), Expect = 4e-19
Identities = 53/167 (31%), Positives = 86/167 (51%), Gaps = 2/167 (1%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+V+ + +T+ V+ A V+ R G GVDNID+ +A K+G+ + N P +
Sbjct: 47 VVLNNFAPMTERVMAAMPPGAVIVRYGVGVDNIDLSAARKRGMRICNVPDYGIEEVADHA 106
Query: 387 CRLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
+ L LAR + +++GRW D+ + L T+ ++GLGR+ R ATRM FG
Sbjct: 107 AAMTLALARKLGRYEAGIRSGRWEIDQMVDGVRSLRDTTVGLIGLGRIARAYATRMAVFG 166
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
IIGFDP+V+ + + + + A ++LH PL TR+
Sbjct: 167 CRIIGFDPYVTETEARSAGIEPLPQDKVIASAHILSLHVPLTPETRD 213
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 97.1 bits (231), Expect = 4e-19
Identities = 53/152 (34%), Positives = 89/152 (58%), Gaps = 2/152 (1%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
V+ +V+ A L+ + R G G+DN+ + ++G+G++ A GANA+ EL+ LML
Sbjct: 60 VSDKVIAAADSLRAISRNGTGIDNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAAL 119
Query: 411 RHVVPASTA-LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
RH +PA TA ++AG W R+ G E+A +T+ I+G G +G+ VA + A ++I DPF
Sbjct: 120 RH-IPAETAGIRAGGWPRS--RGREIAERTVGIIGCGAIGKRVARAVSAMRASVIACDPF 176
Query: 588 -VSADQCAQFHCTXMELEDIWPLADYITLHTP 680
+ + F L++++ AD ++LH P
Sbjct: 177 RPNVEVYGPF--KWASLDEVFAGADIVSLHCP 206
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 97.1 bits (231), Expect = 4e-19
Identities = 63/180 (35%), Positives = 90/180 (50%), Gaps = 14/180 (7%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D +VRSA LD L + RAGAGV+NI +D KGV V N PGANA E
Sbjct: 32 DVALVRSAAM---HDLDLPESLLAIARAGAGVNNIPLDKCADKGVVVFNTPGANANGVKE 88
Query: 381 LTCRLMLVLARHVVPAS----------TALKAGRWDRALYTGSELAGKTLAILGLGRVGR 530
L ML+ +R ++ + K + + G+E+ GK L ++GLG +GR
Sbjct: 89 LVLCGMLLASRDIIGGNKWVANNTDNENISKDMEKAKKNFAGNEIKGKKLGVIGLGAIGR 148
Query: 531 EVATRMYAFGMNIIGFDPFVSADQCAQF----HCTXMELEDIWPLADYITLHTPLIESTR 698
VA + GM + G DPF+S + H E+I+ D+IT+HTPL++ T+
Sbjct: 149 LVANAAESMGMEVYGNDPFISVEGALSLKRDVHLVKTR-EEIFKECDFITVHTPLVDDTK 207
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 96.7 bits (230), Expect = 5e-19
Identities = 55/162 (33%), Positives = 84/162 (51%)
Frame = +3
Query: 195 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 374
N ++ +T+ VL + L+V+ R G G+DN+D+++A + + V N P A A +
Sbjct: 49 NDTVALLAGVEPLTEHVLTSASALRVIARCGTGMDNVDLEAARRLNIQVSNTPEAPAQAV 108
Query: 375 CELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYA 554
ELT LML R + +++ G W R+ G LA +T+ I+GLG +GR VA A
Sbjct: 109 AELTLGLMLDCLRQINRIDRSVRQGEWPRS--QGRLLAARTVGIVGLGHIGRRVAKLCQA 166
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
FG +I DP + Q A + L + AD +TLH P
Sbjct: 167 FGAQVIAHDPHL---QLAPDGVELVALTTLLEQADLVTLHLP 205
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 96.7 bits (230), Expect = 5e-19
Identities = 61/179 (34%), Positives = 92/179 (51%), Gaps = 12/179 (6%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DAL++RS G + + RAGAGV+NI ++ A +G V N PG+NA + E
Sbjct: 32 DALLIRSQDM---HKTPFGTSVLAIARAGAGVNNIPLEKATSQGTAVFNTPGSNANAVKE 88
Query: 381 LTCRLMLVLARHVVPA-STALKAGRWDRALYT--------GSELAGKTLAILGLGRVGRE 533
L ++L+ R V + A K D +L T G+EL GK + I+GLG +G
Sbjct: 89 LIITMLLLSVRPVFASVKWAQKLAGADVSLQTEKGKNHFAGTELYGKKIGIIGLGNIGSR 148
Query: 534 VATRMYAFGMNIIGFDPFVSADQCAQFH---CTXMELEDIWPLADYITLHTPLIESTRN 701
VA GM +IG+DP++S ++ Q LE++ +D+IT+H P + RN
Sbjct: 149 VAKACMDLGMKVIGYDPYISVEKAWQLSNDIPRAESLEELLEQSDFITIHIPYTDKNRN 207
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 96.7 bits (230), Expect = 5e-19
Identities = 51/140 (36%), Positives = 77/140 (55%), Gaps = 1/140 (0%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
L V +G+G D ID+D+ + GV V+N G NA S E+T LML + R + + +L+
Sbjct: 85 LLAVSSSGSGCDTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLR 144
Query: 444 AGRWD-RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 620
A + R G EL G+TL ++G+G GR VA A GM +IG DP + A + +
Sbjct: 145 AHNCESREDLMGHELRGRTLGLVGVGHAGRRVAALGRALGMRVIGCDPALDAAELSARGA 204
Query: 621 TXMELEDIWPLADYITLHTP 680
+ E++ AD ++LH P
Sbjct: 205 QAVSFEELLRSADIVSLHCP 224
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 96.3 bits (229), Expect = 6e-19
Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 3/168 (1%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
L+VRS+ ++++ L +G+ G G+D IDVD+ +G+ + N PG NA + EL
Sbjct: 61 LLVRSSRLTAQDIISCP-NLVAIGKQGVGLDKIDVDACASRGIKIFNTPGVNARAVAELV 119
Query: 387 CRLMLVLARHVVPASTALKAG-RWDRALYTGSELAGKTLAILGLGRVGREVATRMY-AFG 560
L AR V +G + +G L KT+ ILG+G +G+ VA AF
Sbjct: 120 LTLATASARQVGSIIAKQSSGILVPKEKCSGLILHEKTIGILGMGNIGKCVAKIFRGAFD 179
Query: 561 MNIIGFDPFVSADQCAQF-HCTXMELEDIWPLADYITLHTPLIESTRN 701
N+I +DPF+ AD + H +E++ +D IT+H PL TRN
Sbjct: 180 ANVIAYDPFLPADAWEEIPHKRATSVEEVLRSSDVITVHMPLTPETRN 227
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 96.3 bits (229), Expect = 6e-19
Identities = 58/159 (36%), Positives = 88/159 (55%), Gaps = 1/159 (0%)
Frame = +3
Query: 201 DALVVRSATQ-VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 377
D + V + T+ +T V+DA LKV+ R G G+DN+D+++A +G+ V N P +
Sbjct: 48 DCVAVAAGTEPLTARVMDALPGLKVISRCGTGMDNVDMEAARARGIAVRNTPDGPTQAVA 107
Query: 378 ELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
ELT L L L R V L++G W + + G+ L GK L I+G+GR+GR VA
Sbjct: 108 ELTLGLALDLMRQVSRMDRELRSGVWKKRM--GNLLGGKRLGIVGMGRIGRAVADIFTPL 165
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLH 674
G+ + DP VS C + C M +E++ AD ++LH
Sbjct: 166 GVQVAFNDP-VSC--CGDYPC--MPVEELLGWADILSLH 199
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 96.3 bits (229), Expect = 6e-19
Identities = 57/173 (32%), Positives = 91/173 (52%), Gaps = 1/173 (0%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
EI + L +RS T V +LDA +L+ VG G + +D+ +A ++GV V NAP AN
Sbjct: 46 EIASASVLGIRSRTHVDAALLDAAKELQAVGCFCIGTNQVDLVAAAERGVPVFNAPFANT 105
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
S ELT +++L R + A++ G W + +E+ K L I+G G +G +++
Sbjct: 106 RSVAELTMASVIMLMRRIPEKMFAIQRGEWLKTADGANEVRKKKLGIIGYGNIGAQLSVI 165
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
A GM++ +D A + A + M+ L+DI D +TLH P T+N
Sbjct: 166 ASALGMHVYYYD---IAPKLAHGNARPMDTLDDILTECDVVTLHVPSTPRTKN 215
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 95.9 bits (228), Expect = 8e-19
Identities = 57/172 (33%), Positives = 92/172 (53%), Gaps = 3/172 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + VR T++ + + KLKV+ +G G D ID+ A K GV V+N PG +
Sbjct: 54 IQEASGVFVRYPTKLDAQAIGLAKKLKVISTSGFGTDAIDISVATKHGVVVVNNPGLSTT 113
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGRVGREVATR 545
+ E T ++L LA+ + + +K G + R +L GKTL I+GLGR+G VA++
Sbjct: 114 AVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQPMQLEGKTLGIVGLGRIGSAVASK 173
Query: 546 -MYAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIEST 695
AF M ++ +DP+V Q T +E L+ + +D+++LH L + T
Sbjct: 174 CSAAFQMRVLAYDPYVLPSQAEAVGGTLVENLDYLLAESDFVSLHPELTDET 225
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 95.1 bits (226), Expect = 1e-18
Identities = 55/174 (31%), Positives = 91/174 (52%), Gaps = 1/174 (0%)
Frame = +3
Query: 183 MEIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA 359
+EIP+ + L V ++++K+V+D+ LK++ G D+IDV A KG+ V N P
Sbjct: 38 VEIPDDIEILSVFIYSKISKDVIDSLPDLKLIATRSTGFDHIDVAYANSKGITVCNVPSY 97
Query: 360 NALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVA 539
S E LML LAR + ++ G + + G ELAGKTL ++G GR+G A
Sbjct: 98 GEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRGIELAGKTLGVIGTGRIGARTA 157
Query: 540 TRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
FGM+++ +D + ++ ++ ++D+ITLH P + ST +
Sbjct: 158 LLARCFGMDVVCYDARQN-QILIDAGIKYLDFNELLSVSDFITLHVPYLPSTHH 210
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 95.1 bits (226), Expect = 1e-18
Identities = 52/172 (30%), Positives = 88/172 (51%), Gaps = 3/172 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + +AL+ RS +T ++ L+++ RAG+G+DN+D+D + ++ P A
Sbjct: 38 IRDREALIFRSGVNITAGIMACAPDLQLLIRAGSGLDNVDLDYLRNHDLKLVRIPQPGAR 97
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ EL +ML L+R ++ A L+ G W + G L K L I+GLG +G +
Sbjct: 98 AVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRGHLLVNKQLGIVGLGNIGTLLGQMG 157
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELED---IWPLADYITLHTPLIEST 695
A+GM ++G S ++ AQF + L D + ADY+ + PL +T
Sbjct: 158 LAWGMQVLGCVEHPSPERAAQFEAKGLHLTDLNTVLSTADYLCVCVPLKTTT 209
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 94.7 bits (225), Expect = 2e-18
Identities = 50/158 (31%), Positives = 85/158 (53%)
Frame = +3
Query: 228 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
++T+ V +A L V+ R G G + +DV++A G V A G N S + +M+ +
Sbjct: 65 RITRAVFEALPDLAVISRRGVGYEKVDVEAARDLGRVVAIAAGGNDASVADQVIGMMISI 124
Query: 408 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
R A +A+KAG+W+ + G+EL + + I+G GR+GR +A R+ F I+ P
Sbjct: 125 GRRFQEAQSAMKAGKWN--ILVGTELYRRKVGIVGFGRIGRSLARRLSGFEAEILVCAPR 182
Query: 588 VSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
++++ F + E + ADYI++H PL TR+
Sbjct: 183 LASEDIETFGLRHVAFETLLKEADYISVHAPLTPETRH 220
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 94.7 bits (225), Expect = 2e-18
Identities = 57/166 (34%), Positives = 87/166 (52%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
AL +RS+++ T+ V A KL++V G G D++D+ +A + GV V N PG A S E
Sbjct: 52 ALNIRSSSRFTERVFAACPKLRMVSIWGTGTDHVDLAAAARHGVTVANTPGVAARSIAEH 111
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
T L+ +AR + A + G W+R EL GKT ++G G VGR A A GM
Sbjct: 112 TLALLFAVARQIPHMDAATRRGAWERG--QSMELYGKTCGVIGYGAVGRHFARLATAIGM 169
Query: 564 NIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
++ + SA +F LED++ +D I++H L T++
Sbjct: 170 RVMQWTLHPSAYPDVEF----ASLEDLYRASDVISVHLRLSPDTQD 211
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 94.7 bits (225), Expect = 2e-18
Identities = 67/186 (36%), Positives = 96/186 (51%), Gaps = 27/186 (14%)
Frame = +3
Query: 198 HDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 374
HDA ++V S +VT V+ A +L+V+ A NID +A +G+ V+ PG NA +A
Sbjct: 44 HDAEVLVTSYDEVTDAVMAACPRLQVIACTRANPVNIDTQAAQARGIRVLYTPGRNADAA 103
Query: 375 CELTCRLMLVLARHVVPASTALKAGR--------------------WDRA------LYTG 476
ELT LML LARH+ + ALK G WD + ++ G
Sbjct: 104 AELTLGLMLSLARHIPQSHAALKRGEFTQADNASAATQQGLRRDVVWDVSPESPYEVFKG 163
Query: 477 SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLA 656
SEL KTL ++G G +GR VA AFGM ++ DPFV+A+ + LE ++ A
Sbjct: 164 SELRNKTLGLVGYGNIGRRVARIARAFGMAVLVVDPFVAAEDINEPGLQKTTLEALFREA 223
Query: 657 DYITLH 674
D ++LH
Sbjct: 224 DIVSLH 229
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 94.3 bits (224), Expect = 3e-18
Identities = 53/159 (33%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 228 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
++ EV+D LKV+ GVD++D+++A ++G+ V + PG + +LT L+L +
Sbjct: 81 RIDAEVMDRAKGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAV 140
Query: 408 ARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGF 578
AR VV + + G W L G +L G TL ++G+GR+G+ VA R AFGM ++
Sbjct: 141 ARRVVEGAAYARDGLWRAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVV-- 198
Query: 579 DPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
A + LE++ AD ++LHTPL T
Sbjct: 199 ---YHARTPKPLPYPFLSLEELLKEADVVSLHTPLTPET 234
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 94.3 bits (224), Expect = 3e-18
Identities = 55/171 (32%), Positives = 80/171 (46%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ H + +RSAT + ++ +DA L +G G +D+ +A G+ V NAP +N
Sbjct: 64 LQQHQLIGIRSATHLLRDEIDAARHLLAIGCFCIGTSQVDLPAAAHHGIPVFNAPFSNTR 123
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
S EL ++L R V S AG W + E GKT+AI+G G +G +V
Sbjct: 124 SVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFEARGKTIAIVGYGNIGAQVGVLA 183
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A GM ++ +D V A L + LAD +TLH P ST N
Sbjct: 184 EALGMRVVYYD--VQAKLSLGSAQPARSLGEAIALADVVTLHVPAHASTHN 232
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 94.3 bits (224), Expect = 3e-18
Identities = 51/157 (32%), Positives = 84/157 (53%), Gaps = 4/157 (2%)
Frame = +3
Query: 237 KEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARH 416
KE++DAG L+++ G D++D A +KG+ V N+P A + E+T L+L ++
Sbjct: 58 KEMIDAGENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKR 117
Query: 417 VVPASTALKAGRW---DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
+ + +++G W Y G L G TL I G+GR+G VA AFGM ++ D +
Sbjct: 118 LAFYDSIVRSGEWIDPSEQRYQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMTVVYNDVY 177
Query: 588 -VSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ D+ + T +E + + AD IT+H P + ST
Sbjct: 178 RLPEDKEKELGVTYLEFDQLIKTADVITIHAPALPST 214
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 94.3 bits (224), Expect = 3e-18
Identities = 54/169 (31%), Positives = 89/169 (52%), Gaps = 3/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D + + ++ +E+L+ +L+VV G +NID+ +A ++ V V N P A + +
Sbjct: 46 DGALTMLSDKIDRELLEVAPRLRVVANYAVGYNNIDLTAANERHVVVTNTPHCLAEATAD 105
Query: 381 LTCRLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGLGRVGREVATRMY 551
LT L+L +AR +V ++AG W G +L GKTL I+GLG +G VA R
Sbjct: 106 LTMGLLLAVARRLVEGDGLVRAGLFKGWAPEFLLGMDLHGKTLGIIGLGEIGTCVARRAR 165
Query: 552 AFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
AFGM I+ + A ++ +EL ++ +D ++LH PL T+
Sbjct: 166 AFGMRIV-YCARHEAPTASELQAERVELPELLRRSDVVSLHCPLTAETK 213
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 93.9 bits (223), Expect = 3e-18
Identities = 51/161 (31%), Positives = 82/161 (50%)
Frame = +3
Query: 213 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCR 392
+RS TQ+T+EVL+ +L +G G + +D+++A G+ V NAP +N S EL
Sbjct: 60 IRSRTQLTREVLEGADRLMAIGCFCIGTNQVDLNAARMLGIPVFNAPFSNTRSVAELVMG 119
Query: 393 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 572
+++L R + S A G WD++ E+ GKTL I+G G +G +++ AFGM ++
Sbjct: 120 EIVMLLRRIPSRSEACHKGGWDKSATNAWEVRGKTLGIVGYGSIGSQLSVLAEAFGMRVL 179
Query: 573 GFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
FD L D+ +D ++LH P T
Sbjct: 180 YFDVMPRLPHGNAI--AVSTLHDLLAQSDIVSLHVPQTPET 218
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 93.9 bits (223), Expect = 3e-18
Identities = 56/164 (34%), Positives = 91/164 (55%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+ +R T +E L LK++ G +ID+ +A + G+ V+ G + +A ELT
Sbjct: 53 IAMRERTAFGRERLAKLPDLKLLVTTGMANQSIDLRAAEELGI-VVCGTGGSPTAAPELT 111
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
L+L LAR + L+ GRW + G ELAGKTL +LGLG++GR VA AFGM+
Sbjct: 112 WGLLLALARSISFEDRNLREGRWQSTV--GFELAGKTLGVLGLGKIGRRVAAYGQAFGMD 169
Query: 567 IIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
+I + P ++ + AQ + E+++ +D +++H L E +R
Sbjct: 170 VIAWSPNLTGEAAAQAGVRKVSKEELFRDSDVVSVHVRLSERSR 213
>UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH); n=2; Rattus
norvegicus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH) - Rattus
norvegicus
Length = 155
Score = 93.5 bits (222), Expect = 5e-18
Identities = 50/119 (42%), Positives = 75/119 (63%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ + + L ++SAT+VT + ++A KL+VVG AG G+DN+D+++A +K + V+N N+
Sbjct: 39 ELQDCEGLTIQSATKVTADAVNAAQKLQVVGSAGTGMDNVDLEAAMRKSILVMNTSNGNS 98
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT 542
LS ELTC + L A P + + + G+ L GKTL LGLGR+GREVAT
Sbjct: 99 LSPVELTCGMNLCQAD--FPGNNFNERWQMGPEEVHGATLTGKTLGNLGLGRIGREVAT 155
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 93.5 bits (222), Expect = 5e-18
Identities = 56/160 (35%), Positives = 84/160 (52%), Gaps = 3/160 (1%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
V +LDA +L+VV G DN+DV + + + V N PG + +L L+L A
Sbjct: 63 VDAALLDAFPELRVVSNMAVGFDNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAA 122
Query: 411 RHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 581
R++ AS + GRW + G EL G TL ++GLG++G VA R AFGM+I+ +
Sbjct: 123 RNLPAASLDAREGRWQTWSPTGWLGLELRGATLGVVGLGKIGLAVAQRARAFGMDIL-YT 181
Query: 582 PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A + T +EL+ + AD ++LH PL TR+
Sbjct: 182 RRSDAPAPPELGATRVELDALLARADVVSLHVPLRPDTRH 221
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 93.5 bits (222), Expect = 5e-18
Identities = 58/173 (33%), Positives = 92/173 (53%), Gaps = 13/173 (7%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA+++RS T + L G++ + R GAGV+NI V+ KKGV V N+PGAN+ + E
Sbjct: 32 DAILMRS-TDLHGYELPEGIR--AIARCGAGVNNIPVEEYAKKGVVVFNSPGANSNAVKE 88
Query: 381 LTCRLMLVLARHVVPASTALKAGRWD----------RALYTGSELAGKTLAILGLGRVGR 530
L ++++ +R VV + ++ D + + G EL GK + ++GLG VG
Sbjct: 89 LVLGMLVLSSRGVVQSMNWVRDNADDPEIQVDAEKAKKAFVGRELKGKRIGVIGLGNVGS 148
Query: 531 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTXME---LEDIWPLADYITLHTP 680
+VA GM++ G+DPF+S + LED+ DY+T+H P
Sbjct: 149 KVANACVDLGMDVYGYDPFISVEHAWVLSREVQRVGTLEDLCRGCDYLTVHVP 201
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 93.5 bits (222), Expect = 5e-18
Identities = 50/159 (31%), Positives = 78/159 (49%)
Frame = +3
Query: 225 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLV 404
+++T EVL +L+++ G D+ID+D G+ V N P + E L+L
Sbjct: 52 SRLTAEVLAQFPRLRLIATRSTGYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLA 111
Query: 405 LARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDP 584
++RH+V + + G + + G EL GKTL +LG GR+GR V FGM I+ +D
Sbjct: 112 VSRHIVTGAERTRRGDFSQHGLRGFELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVAYDL 171
Query: 585 FVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
F A ++L + AD +TLH P T +
Sbjct: 172 FPDAAVAEHLGYEYLDLHVLLSQADVVTLHVPATPQTHH 210
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 93.5 bits (222), Expect = 5e-18
Identities = 57/172 (33%), Positives = 92/172 (53%), Gaps = 5/172 (2%)
Frame = +3
Query: 198 HDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
HDA+ V EV+DA GVKL ++ R AG DN+D + A ++G+ V+ P +
Sbjct: 79 HDAVCVFVDDDARGEVVDALAERGVKL-ILLRC-AGFDNVDCERARERGISVLRVPAYDP 136
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
LS E +M+ L RH+ + L+ G + GS + GKT+ ++G G++GR VA
Sbjct: 137 LSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVGSSMRGKTVGVVGTGKIGRGVAEI 196
Query: 546 M-YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
+ F M ++G+D F D C + + L+++ +D ++LH PL TR
Sbjct: 197 LKNGFQMRVLGYDKFEKDDFCGDY----VSLDELLARSDVVSLHLPLTPETR 244
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 93.1 bits (221), Expect = 6e-18
Identities = 66/189 (34%), Positives = 98/189 (51%), Gaps = 23/189 (12%)
Frame = +3
Query: 198 HDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 374
HDA +V S +T V+ A +LK++ A NIDV++A ++G+ V+ PG N+ +A
Sbjct: 44 HDADFLVTSYDDITARVIKACPQLKLIACTRANPVNIDVNAATERGIPVVYTPGRNSDAA 103
Query: 375 CELTCRLMLVLARHVVPASTALK-----------AGR-----WD------RALYTGSELA 488
ELT LML LARH+ A +ALK AG WD ++ G EL
Sbjct: 104 AELTIALMLNLARHIPQAHSALKQRQFTATTPGNAGLKTDVVWDVTKDSPYEVFKGVELR 163
Query: 489 GKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYIT 668
KTL I+G G +G+ V AFGM ++ DP+VS + + LE ++ +D++T
Sbjct: 164 NKTLGIVGYGSIGQRVGRIARAFGMQLLVADPYVSEVELDEPGIHKTTLERLFSQSDFVT 223
Query: 669 LHTPLIEST 695
LH + T
Sbjct: 224 LHVKVTPQT 232
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 92.7 bits (220), Expect = 8e-18
Identities = 52/158 (32%), Positives = 89/158 (56%), Gaps = 6/158 (3%)
Frame = +3
Query: 225 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLV 404
T +T+++L KL++V + G G+D ID++ A ++GV V G+NA + E T L+L
Sbjct: 60 TAITEKLLQESPKLRLVHKWGIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILA 119
Query: 405 LARHVVPASTALKAGRWDRALYTG-----SELAGKTLAILGLGRVGREVATRMYAFGMNI 569
R + A +++ G+W +YT +L+GKT+ ILG G +GR VA R+ F + I
Sbjct: 120 ALRRLALADQSMREGKW---IYTELRPLCRKLSGKTVGILGFGNIGRNVAQRLQGFDVEI 176
Query: 570 IGFDPFVSADQCA-QFHCTXMELEDIWPLADYITLHTP 680
I DPF + + + T + +++ ++ +TLH P
Sbjct: 177 IYHDPFRAPPEVEDRLKATYVSFDELIKRSNILTLHCP 214
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 92.7 bits (220), Expect = 8e-18
Identities = 53/169 (31%), Positives = 85/169 (50%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D + +RS + KE + LK +GR GAG++NIDV A KK + + AP N
Sbjct: 64 IGEYDGITIRSRFTIDKEFIKKAKNLKFIGRVGAGLENIDVAYAKKKNIFLAAAPEGNRN 123
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ E T ++L L ++ A+ ++ G+WDR G EL GKT+ I+G G +G+ A ++
Sbjct: 124 AVGEHTLGMLLSLFNNLNKANLEVRNGKWDREGNRGVELDGKTVGIIGYGNMGKAFAKKL 183
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
F + ++ +D MEL+ D ++LH P T
Sbjct: 184 RGFDVEVLCYDIVGGVGDENARQVGIMELQQ---KTDVLSLHVPQTPET 229
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 92.3 bits (219), Expect = 1e-17
Identities = 49/155 (31%), Positives = 80/155 (51%)
Frame = +3
Query: 213 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCR 392
+ ++ V +++L LKV+ RAG G DN+D+D+A + G+ V N PG N + EL
Sbjct: 54 IAASEPVARDMLATSPMLKVIARAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALA 113
Query: 393 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 572
LML AR + + G W R G+EL GK+L ++G G G+ +A A GM ++
Sbjct: 114 LMLACARRLNTVLAGVDDGGWPRE--AGTELRGKSLGVIGYGPSGKAIAALGVALGMRVL 171
Query: 573 GFDPFVSADQCAQFHCTXMELEDIWPLADYITLHT 677
++Q + + + ADY++LH+
Sbjct: 172 VSTAHPDSEQSSGIE--FADFDTTIKAADYLSLHS 204
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 92.3 bits (219), Expect = 1e-17
Identities = 56/170 (32%), Positives = 89/170 (52%), Gaps = 3/170 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVL-DAGVKLKVVGRAGAGVDN-IDVDSAGKKGVGVINAPGANALSA 374
DA + VT++++ A LKV+ G G +DV +A K + V N P AN+L+
Sbjct: 57 DAYIPGGEEVVTEKIIASAKNTLKVISFNGVGYGYYVDVPAAKKHNIAVTNVPHANSLAV 116
Query: 375 CELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM-Y 551
E T L+L L + + + K+G W + Y +++ KT+ I+G+G +GR VA +M Y
Sbjct: 117 SEFTVALILTLMKKIPIMNKETKSGLWHK--YISQDVSDKTIGIVGMGSIGRLVAKKMYY 174
Query: 552 AFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
FG I+ + +D + +EL D+ L+D ITLH P TR+
Sbjct: 175 GFGCKILYYSRTRESDIEQELDAKFVELHDLCRLSDVITLHLPYTSETRH 224
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 91.9 bits (218), Expect = 1e-17
Identities = 56/168 (33%), Positives = 85/168 (50%), Gaps = 7/168 (4%)
Frame = +3
Query: 219 SATQV---TKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
+ATQ+ T +VL L+ VG G N+D+ +A + GV V APG NA +A E
Sbjct: 70 AATQMAPFTADVLAKSPDLRFVGVCRGGPVNVDLQAATEAGVVVSYAPGRNAAAAAEFAV 129
Query: 390 RLMLVLARHVVPASTALKAGRWDRALYT----GSELAGKTLAILGLGRVGREVATRMYAF 557
L+L R + + LK+G W Y G EL G T+ ++G G +GR VA + AF
Sbjct: 130 GLVLAALRRIPASDAELKSGNWRGDYYAYENAGIELEGSTVGLVGYGAIGRIVARVLAAF 189
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
G +++ DPFV + +ELE++ + ++LH L T +
Sbjct: 190 GAHVLVADPFVKPEDATADGVELVELEELLRRSSVVSLHARLTPETHH 237
>UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 327
Score = 91.9 bits (218), Expect = 1e-17
Identities = 55/173 (31%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + DAL+VR ++ ++ D +LK R G G+D I V+ A + + V N P +N
Sbjct: 42 VADADALIVR--VRLPDDIFDHAPRLKACVRHGVGLDFIPVERATRADIAVANLPDSNTQ 99
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGRVGREVATR 545
+ E +L +AR A + W R + G EL +T+ I+GLGR+G +VA
Sbjct: 100 AVAEHVVGAILAMARGFDRLPRAWRNDGWLVRQTFQGIELRDRTVGIVGLGRIGLQVAAA 159
Query: 546 M-YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ + FGM ++G D A + + +E+++ +D+ITLH PL++STR+
Sbjct: 160 LHHGFGMRVLGCDN--GAREGLPSYVDQTSIENVFSGSDFITLHAPLVKSTRH 210
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 91.5 bits (217), Expect = 2e-17
Identities = 49/148 (33%), Positives = 85/148 (57%), Gaps = 2/148 (1%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
L +V GAG D +DV++ GV V+N G NA S E +ML L++ ++ + L+
Sbjct: 90 LLLVSSNGAGFDPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLR 149
Query: 444 AGR-WDRALYTGSELAGKTLAILGLGRVGREVATRMYA-FGMNIIGFDPFVSADQCAQFH 617
R +R G+E+ KT+ I+GLG VGR +A GM ++ +DP+++A+ A+
Sbjct: 150 RERDVNRNDLVGNEVEHKTVGIIGLGNVGRRIAALCNGLLGMKVLAYDPYLTAEVMAERG 209
Query: 618 CTXMELEDIWPLADYITLHTPLIESTRN 701
+EL+++ AD++++ PL + +RN
Sbjct: 210 GEKVELDELLRRADFVSISCPLNKGSRN 237
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/176 (30%), Positives = 92/176 (52%), Gaps = 5/176 (2%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+ L+ + ++ E++D AG +L VV G +NIDVD+A +GV V N P
Sbjct: 128 VKGRHGLLTMLSDRIDGELMDVAGEQLCVVSNYAVGFNNIDVDAAKTRGVVVGNTPDVLT 187
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILGLGRVGREV 536
+ +L L+ +RHV+PA ++ G W+ + G E + KTL I+G+GR+G+
Sbjct: 188 DATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTGWLGVEPSDKTLGIVGMGRIGKAT 247
Query: 537 ATRMY-AFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A R+ +GMN++ D + +EL+ + +D++++H L + TRN
Sbjct: 248 AKRLVGGWGMNLLYTSRSDQGDVEKELGGRRVELDTLLAESDFVSVHVALTDETRN 303
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 91.5 bits (217), Expect = 2e-17
Identities = 59/175 (33%), Positives = 92/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ +V+RS T+V E L L + RAG GV+ I+V+ A + G V+N PG NA + E
Sbjct: 32 EGIVIRS-TKVKDEWLTPD--LLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKE 88
Query: 381 LTCRLMLVLARHVVPAS---------TALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 533
L +L+ +R ++ AS L+ R+ Y G EL GKT+ +LGLG +G +
Sbjct: 89 LVLCCLLLSSRPIIEASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTK 148
Query: 534 VATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
VA Y+ GM+++G+ S + +LE + +DYI + PL E T+
Sbjct: 149 VALSCYSLGMDVLGY----SIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTK 199
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/169 (33%), Positives = 88/169 (52%), Gaps = 4/169 (2%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DAL+ V +E+LDAG KLK+V G G D+IDVD A +G+ V N P + E
Sbjct: 51 DALIT-GKLPVDQELLDAGKKLKIVSATGVGYDHIDVDYASSQGIIVSNCPASVMQPTAE 109
Query: 381 LTCRLMLVLARHVVPASTALKAGRW-DRALY--TGSELAGKTLAILGLGRVGREVATRMY 551
+ L+L L+R + + ++ + D L G GKTL I G+GR+G+ +A+
Sbjct: 110 MAFTLLLALSRKLALYNQEMRQENFLDTGLLENQGQSPVGKTLGIFGMGRIGKTLASYAR 169
Query: 552 AFGMNIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
FGMNI+ + + D+ + + L D+ ADY++L+ P T
Sbjct: 170 TFGMNILYHNRHQLPEDEERALGVSYVPLADLLSQADYVSLNAPATAET 218
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 91.5 bits (217), Expect = 2e-17
Identities = 62/189 (32%), Positives = 97/189 (51%), Gaps = 21/189 (11%)
Frame = +3
Query: 186 EIPNHD-ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
E+P A+++RS EV ++ + R GAG +NI V + G+ V N PGAN
Sbjct: 58 ELPGDPMAMMLRSHKLQVSEVPST---VRGIVRCGAGTNNIPVKEMSELGIPVFNTPGAN 114
Query: 363 ALSACELT-CRLMLVLA------RHVVPASTALKAGRW---------DRALYTGSELAGK 494
A + EL C L+L +HV + G + D+A++ G+E+ GK
Sbjct: 115 ANAVKELVVCSLLLASRGIIEGNKHVNDVINVEENGDYAKISVRIEKDKAMFGGTEIEGK 174
Query: 495 TLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTXM----ELEDIWPLADY 662
TL ++GLG +G V GMN+IG+DP +S + + M +L++++ LADY
Sbjct: 175 TLGVIGLGAIGSRVVNAALGLGMNVIGYDPVLSLEAAWRLPGDKMSRADDLDELFALADY 234
Query: 663 ITLHTPLIE 689
IT+H P I+
Sbjct: 235 ITIHVPYIK 243
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 91.1 bits (216), Expect = 2e-17
Identities = 48/166 (28%), Positives = 86/166 (51%)
Frame = +3
Query: 183 MEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
+EI +V + ++V+D L+ + R G G+D++D+D A +KG+ V N P
Sbjct: 44 IEIAKECVGIVAGVEPLNQKVMDNLPNLRCISRVGVGMDSVDLDYAKQKGIVVTNTPDGP 103
Query: 363 ALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT 542
S ELT + L L R V A +K G W + + G+ + K + ++GLG++G+ A+
Sbjct: 104 TRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--GNLMYEKKVGLIGLGKIGKLAAS 161
Query: 543 RMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
+ AFG +++ FD + +++E + +D I+LH P
Sbjct: 162 QFQAFGCSVMAFDLYPETAWAEANDVEIVDMEKLLAESDIISLHIP 207
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 91.1 bits (216), Expect = 2e-17
Identities = 53/157 (33%), Positives = 82/157 (52%)
Frame = +3
Query: 228 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVL 407
++ +LDA +++ G D +D +A ++G+ V N PG NA + + T ML L
Sbjct: 62 RIDAALLDAMPNCRLIQSVAVGFDGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHL 121
Query: 408 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
RH ++ G W G +L+ T+AILG G +GR VA R+ FG I+ DPF
Sbjct: 122 LRHYAAGHRKVEQGGWGPEGLRGRDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPF 181
Query: 588 VSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
S + Q+ + LE+ AD ++LH PL ++TR
Sbjct: 182 PS-EPGRQY----VALEEAVARADVLSLHMPLNDATR 213
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 91.1 bits (216), Expect = 2e-17
Identities = 47/135 (34%), Positives = 72/135 (53%), Gaps = 1/135 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I DAL++R+ +T +D +LK+V R G G D +DV + +G+ + AN+
Sbjct: 41 IAGADALLIRTQA-LTSPTIDRADRLKIVSRHGVGYDAVDVAALNARGIALAVCGDANST 99
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATR 545
S E C L+L + + A A++ G W R ++ G+ L ILG GR+G+ AT
Sbjct: 100 SVAEHACMLILAAFKRALRADVAVRRGPWGWRNQLESQDIRGRNLLILGFGRIGQHTATM 159
Query: 546 MYAFGMNIIGFDPFV 590
M FGMNI DP++
Sbjct: 160 MSGFGMNIRAHDPYL 174
>UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=13;
Staphylococcus|Rep: NAD-dependent formate dehydrogenase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 389
Score = 90.6 bits (215), Expect = 3e-17
Identities = 50/159 (31%), Positives = 81/159 (50%), Gaps = 2/159 (1%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
+TKE ++ LK+V AG G D++D+ +A + +GV+ G+N +S E +L+L
Sbjct: 116 MTKERIEKAPNLKLVITAGVGSDHVDLQAASEHNIGVVEVTGSNTISVAEHAVMDLLILL 175
Query: 411 RHVVPASTALKAGRWDRALYTG--SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDP 584
R+ K G W+ + EL KT+ I G GR+G+ VA R+ F + I +DP
Sbjct: 176 RNYEEGHRQAKDGEWNLSKVGNHVHELQIKTIGIFGFGRIGQLVAERLAPFNVTIQHYDP 235
Query: 585 FVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
D H T + +++ +D +T+H PL T N
Sbjct: 236 INQKD---NEHSTFVNFDELVSTSDAVTIHAPLTPETDN 271
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/168 (31%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
LV +V ++DA L+ V G GV+++D+D+ ++GV V N PG + +
Sbjct: 48 LVPTYIDRVDAALVDALPALRHVASYGVGVNHLDLDACRRRGVLVTNTPGVVTDATADHA 107
Query: 387 CRLMLVLARHVVPASTALKAGRW---DRALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
L+L AR VV ++AG W D A G+E+ GKT+ ++G GR+G+ A R F
Sbjct: 108 MALLLAAARRVVEGDRVVRAGGWTEVDPAWMLGTEVTGKTVGVVGFGRIGQAFARRARGF 167
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
++ + S + LE + AD+++LH PL+ +TRN
Sbjct: 168 DTRVL----YTSPRDAGVAWAERVGLERLLAEADFVSLHVPLVPATRN 211
>UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Thermococcaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Pyrococcus abyssi
Length = 333
Score = 90.6 bits (215), Expect = 3e-17
Identities = 47/175 (26%), Positives = 90/175 (51%), Gaps = 6/175 (3%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
IP D +++ T++TK++L+ +LKV+ AG D++DV+ A K+G+ V G +
Sbjct: 40 IPELDGIIIAPVTRITKDILERAERLKVISCQSAGYDHVDVEEATKRGIYVTKVSGLLSE 99
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSE------LAGKTLAILGLGRVGR 530
+ E L++ L R + A + ++ G+W+ + E L GK + I+G+G +G+
Sbjct: 100 AVAEFALGLLISLMRKIHYADSFIREGKWESHTFVWREFKEVETLYGKEVGIVGMGAIGK 159
Query: 531 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+A R+ FG I + D + + ++L+++ D + L PL + T
Sbjct: 160 AIARRLKPFGCEIYYWSRHRKEDIEREVNAKYLDLDELLEEVDIVILALPLTKET 214
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 90.6 bits (215), Expect = 3e-17
Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = +3
Query: 213 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCR 392
+RS T +T++V++A KL +G G + +D+D+A K+G+ V NAP +N S EL
Sbjct: 59 LRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIG 118
Query: 393 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 572
+L+L R V A+ G W++ E GK L I+G G +G ++ + GM +
Sbjct: 119 ELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVY 178
Query: 573 GFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
+D ++ + T ++ L D+ ++D ++LH P ST+N
Sbjct: 179 FYD---IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKN 219
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 90.2 bits (214), Expect = 4e-17
Identities = 51/166 (30%), Positives = 91/166 (54%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D L++ + + KEV++A LK++ A G+D+I++++ K + V N+ G + S E
Sbjct: 91 DVLILANMP-LKKEVIEAATNLKMISVAFTGIDHINMETCRKNNIMVCNSAGYSTSSVVE 149
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
LT L+L L R++VP + ++ G + Y+ +LAGKTL ++G G +G EV AFG
Sbjct: 150 LTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQYDLAGKTLGVIGAGDIGTEVIRIGKAFG 208
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
N++ ++ + T L+++ +D +TLH P T+
Sbjct: 209 CNVLVYNR-SEKQHIKELGATQTTLDEVLKNSDIVTLHIPSNNETK 253
>UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Bacteroides fragilis
Length = 306
Score = 90.2 bits (214), Expect = 4e-17
Identities = 56/172 (32%), Positives = 90/172 (52%), Gaps = 1/172 (0%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ + +A+++RS + EVLDA +LK+V RAGAG DN+D+++A GV V+N PG N+
Sbjct: 46 VKDANAIIIRSDI-IDAEVLDAAKELKIVVRAGAGYDNVDLNAATAHGVCVMNTPGQNSN 104
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
+ EL L++ R+ + +G+EL GK L I G VGR VA
Sbjct: 105 AVAELVFGLLVYAVRNFYNGT-------------SGTELMGKKLGIHAYGNVGRNVARIA 151
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
FGM + +D F D + ++ E+++ + ++LH P T+N
Sbjct: 152 KGFGMELYAYDAFCPKDVIEKDGVKAVDSAEELYKTCNIVSLHIPATAETKN 203
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 89.8 bits (213), Expect = 6e-17
Identities = 57/171 (33%), Positives = 89/171 (52%), Gaps = 6/171 (3%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+ + + + E L KLK++ + G +N+D+ +A +G+ V N G S + T
Sbjct: 48 VAITNKVVINAEALTRLPKLKLILVSATGTNNVDLRAAKAQGIVVCNCQGYGTASVAQHT 107
Query: 387 CRLMLVLARHVVPASTALKAGRWDRAL------YTGSELAGKTLAILGLGRVGREVATRM 548
LML LA ++ A+ GRW +A Y EL+GKTL I+G G +G+EVA
Sbjct: 108 LTLMLALATSLLRYDHAVAQGRWQQASQFCFLDYPIIELSGKTLGIVGYGELGKEVARLA 167
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFGM I+ + Q + H +ELE + P D+++LH PL E T++
Sbjct: 168 QAFGMKIL----IANLPQRPK-HEDRLELEALLPQVDFLSLHCPLTEHTQH 213
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 89.8 bits (213), Expect = 6e-17
Identities = 54/168 (32%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ L+V + T V ++L +L+ V A G DN+D+++ K G+ V N P A+A S E
Sbjct: 41 EILIVTTFTPVNGDLLKKMPRLRFVQVASIGYDNVDMNAMKKNGIMVSNIPTASADSVAE 100
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
++L L + +++GRW R + S+L GKT I+G+G +GR +A R+ F
Sbjct: 101 HALSMVLSLIKDQRFLDAEIRSGRWPR-ITRSSDLMGKTFGIVGMGSIGRALAARLLPFK 159
Query: 561 MNIIGFD-PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ II D +S + ++ T + L+ + +D I++H PL E+TR+
Sbjct: 160 VAIIYNDTKRMSEAEEEEYGATFVSLDRLLSDSDVISVHVPLNETTRH 207
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 89.4 bits (212), Expect = 7e-17
Identities = 53/172 (30%), Positives = 91/172 (52%), Gaps = 3/172 (1%)
Frame = +3
Query: 195 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 374
N AL++RS+ +T E + + L +G+ G G++ ID D+ K+G+ ++N PGANA
Sbjct: 476 NARALLIRSS-YLTAEDIASCPNLVAIGKHGVGIEKIDQDACVKRGIKILNTPGANARDV 534
Query: 375 CELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMY- 551
EL L L +AR + +T + + G L KT+ I+G+G +GR VA
Sbjct: 535 AELVVTLALSVARGIRSITTRQMSKPVPKETCNGLTLYQKTIGIIGMGNIGRTVAEIFRG 594
Query: 552 AFGMNIIGFDPFVSADQCAQF--HCTXMELEDIWPLADYITLHTPLIESTRN 701
F +I+ +D + + D Q H ++++ AD +++H PL + TR+
Sbjct: 595 GFAADIVAYDAY-TPDNIWQHIPHVRARSIDEVLVRADVLSIHVPLTKDTRD 645
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 89.0 bits (211), Expect = 1e-16
Identities = 58/160 (36%), Positives = 85/160 (53%), Gaps = 11/160 (6%)
Frame = +3
Query: 255 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPAST 434
G KLK + + G GVD ID+ +A K G+ V+N PG NA + EL +ML LAR
Sbjct: 96 GGKLKYISKQGTGVDKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDR 155
Query: 435 ALKAGRWDRAL--YTGSELAGKTLAILGLGRVGREVATRMY--AFGMNIIGFDPFV---- 590
++ G L + G L GKTL ++G G +G VA +M+ AF I+ +DP++
Sbjct: 156 KIRKGASVTKLDGWKGQMLYGKTLGVIGGGNIGLLVA-KMFAGAFSGKIVLYDPYLKSLD 214
Query: 591 ---SADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
SA A H E++++ +D +T+H PL ST N
Sbjct: 215 TWHSAIPNASIH-KVSEIDELLTTSDIVTIHVPLTPSTEN 253
>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
- Gibberella zeae PH-1
Length = 1068
Score = 88.6 bits (210), Expect = 1e-16
Identities = 54/177 (30%), Positives = 96/177 (54%), Gaps = 7/177 (3%)
Frame = +3
Query: 192 PNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALS 371
P+ A++++ +T++ L + +L+V+G+ G G+D IDV++ + V V N PG NA +
Sbjct: 790 PHATAILIKDY-YITEDDLASAPQLRVIGKQGVGLDKIDVEACKRHNVKVCNTPGVNASA 848
Query: 372 ACELTCRLMLVLARHV--VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
E+T L L +AR V V ++ + G L+ K + ++G+G +G+ +A +
Sbjct: 849 VAEMTLCLALTVAREVPDVVIRQKIQGEAIRKETVAGMLLSRKIIGVVGMGHIGQAIA-Q 907
Query: 546 MYAFGM--NIIGFDPFVSADQCAQFHCTXMELE---DIWPLADYITLHTPLIESTRN 701
M+ G+ II FDP+ +Q +E ++ +AD +TLH PL ST+N
Sbjct: 908 MFVGGLQAEIIAFDPYFHDNQGPWDTIPYKRVETLTELLEVADVVTLHVPLTHSTKN 964
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 88.6 bits (210), Expect = 1e-16
Identities = 54/164 (32%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
V AT + L+A +KVV R G G D +DV + ++ V ++ A AN+ S E
Sbjct: 55 VALGATAFGETELEASKDMKVVTRIGVGYDAVDVPALSRRKVPLMVAGSANSPSVAEQAL 114
Query: 390 RLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
+ML LA+ + +K G+W DR +L GKT+ I+G GR+G A R A M
Sbjct: 115 FMMLTLAKRAQEMHSCVKDGKWADRLGMLPFDLYGKTVLIIGFGRIGTRTAKRCLAMEMR 174
Query: 567 IIGFDPFVSADQC-AQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ +DP+ A + A + +L+ P AD++T+H P T
Sbjct: 175 VQVYDPYKPAAEIKAAGYEPVADLDAALPHADFVTIHCPKTPET 218
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 88.6 bits (210), Expect = 1e-16
Identities = 54/173 (31%), Positives = 89/173 (51%), Gaps = 4/173 (2%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I +D ++V KE++DA LKV+ G G D+ID+D A +KG+ V N P +
Sbjct: 46 IAKYDGVIVAKMI-FDKEIIDAAKNLKVISTYGVGFDHIDIDYAREKGIVVTNCPNSVLR 104
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRW---DRALYTGSELAGKTLAILGLGRVGREVA 539
EL +++ AR + AL+ G + D G + GKTL ILG+GR+G++VA
Sbjct: 105 PTAELALTMIMASARRIRYYDHALREGVFLNVDEYDSQGYTIEGKTLGILGMGRIGQQVA 164
Query: 540 TRMYAFGMNIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
A GM II + + + A+ + ++ + +D+++LH P + T
Sbjct: 165 RFAKALGMKIIYHNRHQLKPELEAELNARYVDFASLVKNSDFLSLHAPATDET 217
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 88.6 bits (210), Expect = 1e-16
Identities = 49/153 (32%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +3
Query: 240 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHV 419
+ L LK++ R G G DN+D AG+ GV V P ANA + E T +L L++++
Sbjct: 55 QTLTKFTNLKIIARHGVGFDNVDEKFAGEHGVYVTITPMANASTVAETTIAEILDLSKNL 114
Query: 420 VPASTALKAGRWDRAL-YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSA 596
S ++ G + L + G +L+ K + ++G GR+GR+VA + A GM+++ FDPFV
Sbjct: 115 TKISDEMRQGNFAYKLDHMGFDLSHKKIGVMGYGRIGRQVAEKANALGMDVLIFDPFVKE 174
Query: 597 DQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ + ++ + + +D ITLH + + T
Sbjct: 175 TKIGKL----VDRDTLISQSDVITLHLAVTDQT 203
>UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: D-3 phosphoglycerate
dehydrogenase - Bacillus sp. B14905
Length = 319
Score = 88.6 bits (210), Expect = 1e-16
Identities = 49/153 (32%), Positives = 78/153 (50%)
Frame = +3
Query: 240 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHV 419
EV+D LK++ A GVD++ + A + V V NA G + ELT L+L + RH+
Sbjct: 63 EVIDQNANLKLINVAFTGVDHVGIGQARNQDVMVCNAAGYANQAVAELTIGLVLDVYRHI 122
Query: 420 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD 599
+ A + A + GSE+ GKT+ ++G G++G A AFG I+ D
Sbjct: 123 TQGDKEIHADHFPGA-FQGSEIKGKTVGLIGTGKIGMMTARLFKAFGAKIVASDQSRRNP 181
Query: 600 QCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
MEL+++ +D ++LH PL+ ST+
Sbjct: 182 AAEVLGIEYMELDELLAQSDIVSLHIPLLSSTK 214
>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mycobacterium gilvum
PYR-GCK
Length = 298
Score = 88.2 bits (209), Expect = 2e-16
Identities = 49/145 (33%), Positives = 74/145 (51%)
Frame = +3
Query: 261 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTAL 440
KLK V R G G+D++D ++A + GV V N PG + +L LAR + A+
Sbjct: 62 KLKTVIRWGIGMDSVDHEAARRHGVTVRNTPGVFGYEVADSAFGYILNLARGYMAVDAAV 121
Query: 441 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 620
+ G W + G L G L I+G G +GRE+A R FG ++ FDPFV A
Sbjct: 122 RRGEWPKV--EGITLDGSRLGIVGFGAIGREIAKRGAGFGQEVVAFDPFVKASPAG---V 176
Query: 621 TXMELEDIWPLADYITLHTPLIEST 695
+ +EL+++ + ++ L PL T
Sbjct: 177 SMVELDELLATSRFVVLACPLTPET 201
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 88.2 bits (209), Expect = 2e-16
Identities = 50/165 (30%), Positives = 79/165 (47%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+VV V+ E L + +LK++ G DN+D++ A GV V N P S E
Sbjct: 47 IVVVGRYGVSAEALRSAPRLKMISLWQTGFDNVDLEEATDHGVIVSNVPSYAFESVAEFV 106
Query: 387 CRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 566
L L L R V A L+ G +D Y G++L KT+ +LG G +G+ V + F MN
Sbjct: 107 FALTLNLLRRVHLADMNLREGLFDWKYYVGNQLMSKTIGVLGTGEIGKRVIQIAHGFNMN 166
Query: 567 IIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
++ S ++ ++L+ + +D +TLH PL T +
Sbjct: 167 VLSVTAHPSPERAKALGVKFVDLDTLLSESDIVTLHVPLTPETEH 211
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 88.2 bits (209), Expect = 2e-16
Identities = 48/145 (33%), Positives = 77/145 (53%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
LK+V G D++D+D+A KGV V NAPG + + E ++L R + A ++
Sbjct: 66 LKLVALTRTGYDDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIR 125
Query: 444 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT 623
++D + G EL GKT+ I+G G++G VA FGM++I +D V +
Sbjct: 126 EEKFDCTAFEGRELRGKTMGIIGTGQIGLRVAEIARCFGMDVIAYD--VRRNPAVAEKLR 183
Query: 624 XMELEDIWPLADYITLHTPLIESTR 698
+ L+ + +D+IT+H PL TR
Sbjct: 184 YVGLDRLCAESDFITVHLPLTSDTR 208
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 87.4 bits (207), Expect = 3e-16
Identities = 56/174 (32%), Positives = 87/174 (50%), Gaps = 3/174 (1%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ + DA++ R + E LDA LK++ G+G + I +A +GV V NAP N+
Sbjct: 39 EVGDADAVITRDLG-FSAEALDAAPNLKIISCHGSGTNRIAKAAAAARGVLVTNAPNTNS 97
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVA- 539
S E+T L+L + R + A A++ G W+ R G EL +TL ++G G + R VA
Sbjct: 98 RSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGMELHTRTLGLVGFGAIARHVAQ 157
Query: 540 TRMYAFGMNIIGFDPFVSADQCAQFHCTXM-ELEDIWPLADYITLHTPLIESTR 698
GM ++ + P V AD L+D+ +D ++LH P S R
Sbjct: 158 IAGQGLGMRVMAWSPSVPADVFEGAGVMRANSLDDLLVASDVLSLHRPAQGSGR 211
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 87.4 bits (207), Expect = 3e-16
Identities = 60/177 (33%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ +VVR A + L+ KL+ + R GAG+D I V +A + G+ V N P NA
Sbjct: 35 ELAEASFVVVRRA--IPAGALENAPKLRALVRHGAGLDFIPVQAASRLGIAVTNTPSVNA 92
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWD--RALYTGS-ELAGKTLAILGLGRVGREV 536
S E L++ LAR +V ++ W RA GS E+AGK L ++G G +G+ +
Sbjct: 93 KSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAAPGSCEIAGKALGLIGYGGIGQAI 152
Query: 537 A-TRMYAFGMNIIGFDPFVSADQ-CAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
A FGMN++ + D+ FH L D+ AD + + PL E TRN
Sbjct: 153 AQIGKLGFGMNVLAATRWPREDEDGVSFH----PLTDVAAKADILVVACPLSEETRN 205
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 87.4 bits (207), Expect = 3e-16
Identities = 51/171 (29%), Positives = 90/171 (52%), Gaps = 1/171 (0%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I + A+ +RS T++T VL L +G G + +D+D A +G+ V N+P +N+
Sbjct: 97 KIKDVHAIGIRSKTRLTSNVLQHAKNLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNS 156
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
S EL ++ LAR + S L G W++ E+ GKTL I+G G +G +++
Sbjct: 157 RSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVL 216
Query: 546 MYAFGMNIIGFD-PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
A G++++ +D + A A+ T L+++ +D++TLH P T
Sbjct: 217 AEAMGLHVLYYDIVTIMALGTARQVST---LDELLNKSDFVTLHVPATPET 264
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 87.0 bits (206), Expect = 4e-16
Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 3/165 (1%)
Frame = +3
Query: 195 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 374
N DA+ + +TK ++DA KV+ GVD++DV +A +G+ V N P
Sbjct: 91 NADAIYAKGIP-ITKSIIDALESCKVITLGSVGVDSVDVKAATARGIPVTNIPDTFIEEV 149
Query: 375 CELTCRLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREVATR 545
+ L+L R +V +++GRW AL L G+TL + GRV R VA R
Sbjct: 150 ADHAMMLLLAGFRRLVEQDRMVRSGRWAEGRPALLKIPRLMGQTLGFISFGRVARAVAKR 209
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
FG+ ++ +DPF+ L ++ +D++++H P
Sbjct: 210 AAPFGLRMMAYDPFIQETLMYDHGVIPATLNEVLSQSDFVSMHAP 254
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 87.0 bits (206), Expect = 4e-16
Identities = 55/164 (33%), Positives = 88/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+V+ S ++ + L A KL+ + G +N+DV++AGK+G+ V N P + S + T
Sbjct: 51 IVLTSKVKLDEATLAALPKLRYISMLATGYNNVDVEAAGKRGIPVANIPAYSTESVVQTT 110
Query: 387 CRLMLVLARHVVPASTALKAGRW----DRALYTGS--ELAGKTLAILGLGRVGREVATRM 548
L+L LA HV +A+KA W D + + EL G TL I+G G +GR VA
Sbjct: 111 FALLLELAVHVGIHDSAVKAREWVRSPDHSFWKTPIVELDGLTLGIVGYGTIGRAVARVG 170
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
AFGM I+ + P V AD + L++++ +D ++L+ P
Sbjct: 171 AAFGMKIMAYAPRVPAD-LGPVPVRFVSLDELFAGSDVVSLNCP 213
>UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp.
SK209-2-6|Rep: Dehydrogenase - Roseobacter sp. SK209-2-6
Length = 343
Score = 87.0 bits (206), Expect = 4e-16
Identities = 46/167 (27%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
A ++ ++ E + + +V+ R G GVD +DV++A KG+ V N +
Sbjct: 59 AAMMNQYARIGHETITRMQRCEVIARYGVGVDIVDVNAATAKGILVTNVQNYCTEEVADH 118
Query: 384 TCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
L L LAR + A AG W ++ L G+T+ ++ LG++G+ +A R AFG
Sbjct: 119 AIALWLALARKLPDYDRATHAGLWQWQSGQPVHRLRGRTMGVVSLGKIGQAIAARARAFG 178
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+N+I +DPF+ + A+ + ++ +DYI + P+ T +
Sbjct: 179 VNVIAYDPFLPGEAAAKLGVELVGKPELLARSDYILMQAPMTPDTHH 225
>UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1;
Flavobacteriales bacterium HTCC2170|Rep: D-lactate
dehydrogenase - Flavobacteriales bacterium HTCC2170
Length = 335
Score = 87.0 bits (206), Expect = 4e-16
Identities = 46/155 (29%), Positives = 82/155 (52%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
V +++ D GVK + AG +NI + +A + G+ V NAP + + EL L++ +
Sbjct: 59 VLEKLRDLGVKY--ITLRSAGYNNIQIKAAKRFGLKVANAPDYSPNAIAELAVALLMTIN 116
Query: 411 RHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV 590
R ++ A + A +D+ G +L KT+ ++G+GR+G + M+ FG NI+ D
Sbjct: 117 RKIIVADKQVHAHNFDQKNLLGCDLVHKTVGVIGVGRIGSVMVKIMHGFGCNILAHDLQP 176
Query: 591 SADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ D ++ LE+++ +D I+LH PL T
Sbjct: 177 NGDLVEKYQVKYTSLEELYAQSDIISLHVPLTHET 211
>UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=15;
Campylobacterales|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Campylobacter jejuni
(strain RM1221)
Length = 311
Score = 86.6 bits (205), Expect = 5e-16
Identities = 55/163 (33%), Positives = 86/163 (52%), Gaps = 6/163 (3%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
+ K+V+DA LK++ GV+NID++ A +KG+ V NA G + +S + T M
Sbjct: 53 IDKDVIDACKNLKLILETATGVNNIDIEYAKEKGIIVKNAAGYSTMSVVQHTFAFMFAFL 112
Query: 411 RHVVPASTALKAGRW-DRALYTG-----SELAGKTLAILGLGRVGREVATRMYAFGMNII 572
V K G+W + ++T + L+GK I+GLG +G+EVA AFG I
Sbjct: 113 NQVPYYDKWSKEGKWCESPIFTDYSRILNTLSGKKHGIIGLGTIGKEVAKISKAFGAEIY 172
Query: 573 GFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ A++ A F +EL+D+ D I++H PL E T+N
Sbjct: 173 YYST-SGANKNADF--VHLELKDLLKTCDIISIHAPLNEKTKN 212
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 86.6 bits (205), Expect = 5e-16
Identities = 51/163 (31%), Positives = 81/163 (49%)
Frame = +3
Query: 213 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCR 392
VRS T+V + +A +L VG G D ID++ A + GV V NAP +N S EL
Sbjct: 49 VRSKTKVRAPIFEAVPRLAAVGAFCIGTDQIDLEVAAQSGVAVFNAPFSNTRSVAELVIA 108
Query: 393 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 572
++ L+R + S A GRW + E+ GKTL I+G G +G +++ A G+ +
Sbjct: 109 EIVCLSRQLFERSWAAHEGRWRKDAKGAHEVRGKTLGIIGYGHIGSQLSVLAEAMGLR-V 167
Query: 573 GFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ V+ + L+ + +D+++LH P TRN
Sbjct: 168 RYHDIVNKLPLGNASASE-SLDALLAGSDFVSLHVPNTPQTRN 209
>UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Pyrobaculum aerophilum|Rep: D-3-phosphoglycerate
dehydrogenase - Pyrobaculum aerophilum
Length = 323
Score = 86.2 bits (204), Expect = 7e-16
Identities = 54/168 (32%), Positives = 83/168 (49%), Gaps = 2/168 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ALV+ + KEVLDAG KLK+V A GVD+IDV+ A +KGV V + P + +
Sbjct: 53 EALVIFIGDVIDKEVLDAGEKLKIVSTASVGVDHIDVEYAKRKGVVVAHTPYVLVDAVAD 112
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDR--ALYTGSELAGKTLAILGLGRVGREVATRMYA 554
L L++ + R + +++G D G L GK I+GLG +G +A R+ A
Sbjct: 113 LAVGLLIAVTRKIALGDRLIRSGAADAVWGSLMGVNLRGKRAGIVGLGNIGVAIARRLKA 172
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
F + + + + MEL+ + +D+I L L TR
Sbjct: 173 FDIEVAYWSRRRKPEVEFALGIEYMELDSLLSSSDFIFLTMALTPETR 220
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 85.8 bits (203), Expect = 9e-16
Identities = 60/169 (35%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++ R A + AG +L+ V GAG D +D ++A +KGV V N PGANA S E
Sbjct: 43 DAVITRDAG-LDAAAFAAGDRLRAVVVHGAGHDPVDKEAAARKGVVVANTPGANARSVAE 101
Query: 381 LTCRLMLVLARHVVPASTALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRM-YA 554
L L L +AR + A AL+ G+ R SEL G+T ++G G GRE + A
Sbjct: 102 LAVGLALAVARRIPAADRALREGKTGFRESARFSELRGRTALVVGWGASGRETGRMLAQA 161
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
F M ++ P V + + L + AD ++LHTPL T +
Sbjct: 162 FDMRLLVHSPRVPRIEGGE---RVASLAEGLAAADLVSLHTPLRPETHH 207
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 85.8 bits (203), Expect = 9e-16
Identities = 65/173 (37%), Positives = 85/173 (49%), Gaps = 7/173 (4%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
A VV +V E+LDA G L+VV G DNIDV +A GV V N PG + +
Sbjct: 51 AAVVTLTERVDAEILDAAGDGLRVVANVAVGYDNIDVAAAHAAGVTVTNTPGVLDNATAD 110
Query: 381 LTCRLMLVLARHVVPASTALKAGR---WDRALYTGSEL-AGKTLAILGLGRVGREVATRM 548
T L+L + R VV L++ R W + TG ++ AG TL ILG GR+GR VA R
Sbjct: 111 HTFALILAVTRRVVDGDRFLRSRRPWIWGPRMLTGLDVSAGATLGILGYGRIGRAVARRA 170
Query: 549 YAFGMNIIGFD--PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AF M ++ AD F T L D +D + + TPL TR+
Sbjct: 171 RAFDMTVLATSRRRTSGADDDVWFVDTDTLLAD----SDVVCVLTPLTPETRH 219
>UniRef50_A0AFI6 Cluster: Complete genome; n=1; Listeria welshimeri
serovar 6b str. SLCC5334|Rep: Complete genome - Listeria
welshimeri serovar 6b (strain ATCC 35897 / DSM 20650
/SLCC5334)
Length = 349
Score = 85.8 bits (203), Expect = 9e-16
Identities = 50/172 (29%), Positives = 93/172 (54%), Gaps = 5/172 (2%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D L+V A V+K+++ + KL+++G + G++N+ V++A ++ + VI+ NA +
Sbjct: 74 DILLVHIAP-VSKKMIASAKKLRLIGASRGGMENVAVEAATERKIPVIHVI-RNAEPVAD 131
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGS---ELAGKTLAILGLGRVGREVATRMY 551
T LM R++ A ++K GRWD+ + LA T+ ++GLG +G+ VA R+
Sbjct: 132 FTVALMYAETRNIARAHLSIKNGRWDKGFSNDAYKTTLAKHTVGLIGLGYIGKLVAKRLN 191
Query: 552 AFGMNIIGFDPFVSADQCAQ--FHCTXMELEDIWPLADYITLHTPLIESTRN 701
G+ +I +DPF+ + L +++ AD I+LH + + T N
Sbjct: 192 GLGVKVIAYDPFIDPKKLVDEGLDIELKGLHEVFREADIISLHMRVTKETTN 243
>UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2;
Entamoeba histolytica|Rep: D-phosphoglycerate
dehydrogenase - Entamoeba histolytica
Length = 299
Score = 85.8 bits (203), Expect = 9e-16
Identities = 55/170 (32%), Positives = 89/170 (52%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + D ++VRS ++ +E++ AG K+K++ RAGAG DNID+++ + + V+N PG N
Sbjct: 46 IKDADGVIVRS-DKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRN 104
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
EL +M+ R K G+ G EL KTL I G G VG+ V
Sbjct: 105 GVAELCIGMMIFGFR------KGFKEGK-------GRELKDKTLGICGCGYVGKRVKEIA 151
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
GM I +DPF++ + + ++E+++ I+LH PL + T+
Sbjct: 152 EGIGMKIKVYDPFITTENQVK------KIEELFEECQVISLHLPLTKETK 195
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 85.4 bits (202), Expect = 1e-15
Identities = 51/143 (35%), Positives = 78/143 (54%), Gaps = 3/143 (2%)
Frame = +3
Query: 270 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA-CELTCRLMLVLARHVVPASTALKA 446
++ R G G D ID++SA KKG V G A E L+L + R V AS +K
Sbjct: 97 LIARHGIGYDAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKE 156
Query: 447 GRW-DRALYTGSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHC 620
G+W +RA + G E+ GKT I+G+G +G VA + Y FG +I +DP +S ++ +
Sbjct: 157 GKWHERANFIGYEIKGKTAGIIGIGNIGSRVAEILKYGFGAEVIAYDPNLSKEEIIKREA 216
Query: 621 TXMELEDIWPLADYITLHTPLIE 689
+ LE++ +D I+L+ L E
Sbjct: 217 RPVSLEELLRSSDIISLNASLNE 239
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 85.4 bits (202), Expect = 1e-15
Identities = 49/169 (28%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
A V+ + + +EV +LKV+ G DNID+ A K GV V N P + EL
Sbjct: 48 ACVITLSEHIDEEVFLRAQQLKVIANMAVGFDNIDISLAKKHGVVVTNTPHVLTETTAEL 107
Query: 384 TCRLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREVATRMYA 554
LML +AR ++ A++ ++ G+W L +G ++ G T+ I G+G +G+ A R+
Sbjct: 108 GFTLMLTVARRIIEATSYIQEGKWKSWGPYLLSGKDVYGATVGIFGMGDIGKAFARRLQG 167
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
F II + + + T + + + +D+I PL + T N
Sbjct: 168 FDARIIYHNRKRDLNAERDLNATYVTFKSLLEQSDFIICTAPLTKETEN 216
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 85.4 bits (202), Expect = 1e-15
Identities = 57/161 (35%), Positives = 85/161 (52%), Gaps = 15/161 (9%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHV------VP 425
L V RAGAG +N++V+ A KKG+ V N PGANA + +L ++ V R++
Sbjct: 51 LLAVARAGAGTNNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCK 110
Query: 426 ASTALKAGRWD------RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 587
+ TA+ + D ++ Y G E+AGK L ++GLG++G +A MN+ GFDP
Sbjct: 111 SLTAVDPDKVDSVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDPA 170
Query: 588 VSADQCAQFH---CTXMELEDIWPLADYITLHTPLIESTRN 701
+ + Q L+D AD I+LH PL + TRN
Sbjct: 171 PALENIHQLSPQVRVCRALKDAVSDADVISLHLPLNDRTRN 211
>UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia phymatum STM815
Length = 321
Score = 85.4 bits (202), Expect = 1e-15
Identities = 48/167 (28%), Positives = 82/167 (49%), Gaps = 4/167 (2%)
Frame = +3
Query: 213 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCR 392
+ + ++ E L +LKV+ G D DVD K+G+ + N P S +
Sbjct: 46 IGTGVKMNAETLADASRLKVLSTVSVGFDAFDVDYLNKRGILLTNTPDVLTESTADTAFS 105
Query: 393 LMLVLARHVVPASTALKAGRWDRALYT---GSELAGKTLAILGLGRVGREVATR-MYAFG 560
L+L+ AR + + +KAG+W + + G ++ KTL I+GLGR+G VA R F
Sbjct: 106 LILLTARRLAELAAFVKAGKWTKKIAEDRFGVDVHHKTLGIVGLGRIGTSVARRAALGFQ 165
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
MN++ D V+ ++ + +++ +D++ L PL TRN
Sbjct: 166 MNVLYVDQGVNEKAEREYGAKRVSFDELLKTSDFVLLQAPLTPETRN 212
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 85.0 bits (201), Expect = 2e-15
Identities = 59/177 (33%), Positives = 88/177 (49%), Gaps = 6/177 (3%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I DA++VR Q+ E++D +L V+ G G D I V A G+ V+ P AN
Sbjct: 40 IAGADAVLVRD--QLPAELIDMAPRLCVIANHGTGTDKIAVAHADALGIPVVYTPQANVR 97
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRW----DRALYTGSELAGKTLAILGLGRVGREV 536
S E LMLV AR V A A + G W ++ +Y+ L GKTL ++GLGR GR +
Sbjct: 98 SVAEHALMLMLVTARQAVQADAATRKGHWGFKYEQPMYS---LYGKTLGVIGLGRTGRLL 154
Query: 537 ATRMY-AFGMNIIGFDPFVSADQCAQFHCTXME-LEDIWPLADYITLHTPLIESTRN 701
A M + + P + A + ++ L+++ AD ++LH PL TR+
Sbjct: 155 CEMAAPALNMQALVWSPSLPAGEALPPGARRVDTLQELLREADVVSLHRPLRPDTRH 211
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 5/165 (3%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D L+ A +T+ + +A L++V + GVDNID+++A V V + PG + +
Sbjct: 48 DVLLSVLADPITEALFEARPGLQMVSQYAVGVDNIDLEAAEAHDVAVTHTPGVLTDATAD 107
Query: 381 LTCRLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGLGRVGREVATRMY 551
L+L ARHV A ++ G RW+ G ELA KT+ I+G+GR+G VA R
Sbjct: 108 QAWALLLAAARHVPAADRYVRDGRFERWETTHLMGMELARKTIGIVGMGRIGTAVARRAL 167
Query: 552 AFGMNIIGFDPFVSADQCA--QFHCTXMELEDIWPLADYITLHTP 680
FGM +I + A+ Q + L ++ +D ++LH P
Sbjct: 168 GFGMEVI-YHNRTRANPTVERQVSARHVGLGELLTTSDVVSLHCP 211
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 85.0 bits (201), Expect = 2e-15
Identities = 54/162 (33%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Frame = +3
Query: 198 HDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 377
H V+ E+ DA K V+ R G G DNI++ A +KG+ N PGA S
Sbjct: 44 HAKYVIVGGAPYRNELYDAVPKGGVIARFGIGCDNINLPRAAEKGIYCTNTPGALEQSVA 103
Query: 378 ELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT-RMYA 554
E ++L+ AR + A+ + G W TG ELAGKTLA++G G +G VA
Sbjct: 104 ECAIGMILLAARQFIAAADDCRNGLWQP--QTGCELAGKTLAVIGCGAIGSRVAAIAKNG 161
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTP 680
FGM++ G C D AD+++LH P
Sbjct: 162 FGMSVTGVIRSAPRPDCPADRFV-KNWSDAVADADFVSLHIP 202
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 85.0 bits (201), Expect = 2e-15
Identities = 48/174 (27%), Positives = 86/174 (49%), Gaps = 4/174 (2%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+ DA++ V E+LDA G + K++ G +N ++D+A K+GV + N PG
Sbjct: 44 VKGRDAVITLLTDNVDAEILDAAGPQCKIIANYAVGFNNFNLDAATKRGVIMTNTPGVLD 103
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILGLGRVGREV 536
+ L+L A+ + + ++ G+ W + G ++ GKTL I GLGR+G
Sbjct: 104 KATATHAWALLLATAKRISESERYVREGKWKGWSPMTFIGQDVDGKTLGIAGLGRIGTMF 163
Query: 537 ATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
A + AF M +I + + D T ++ E + +D++++H PL T+
Sbjct: 164 ARKAAAFDMKVIYTNEQRNFDFEKDHGATFVDKETLLKESDFLSIHLPLTPETK 217
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 85.0 bits (201), Expect = 2e-15
Identities = 51/163 (31%), Positives = 82/163 (50%), Gaps = 2/163 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+ LV +V E+L +L+V+ +A G DN+D+ + ++G+ N PG + +
Sbjct: 48 EGLVSTGDVRVDDELLAHAPRLRVIAQASVGYDNVDIAACTRRGIPFGNTPGVLVEATAD 107
Query: 381 LTCRLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVATRMYA 554
LT L+L AR + + +GRW + + G +L GKTL I+G+GR+G VA R A
Sbjct: 108 LTFGLLLCAARRIHEGWNQVASGRWLNNHDVPFGIDLYGKTLGIVGMGRIGAAVARRAKA 167
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPL 683
GM +I + D T + +D+ AD I + PL
Sbjct: 168 CGMKVIYHNRSRRTDD-EHLGATYVAFDDLLAQADCIVVLVPL 209
>UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 327
Score = 85.0 bits (201), Expect = 2e-15
Identities = 55/170 (32%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA++ VTKE L +LK + A G DN D+ + + GV V P E
Sbjct: 48 DAMMAFMTDSVTKESLLNAPRLKTISCALKGYDNFDLRACAQAGVSVTFVPDLLTEPTAE 107
Query: 381 LTCRLMLVLARHVVPASTALKAG--RWDRALYTGSELAGKTLAILGLGRVGREVATRMYA 554
L L + R+V+ A +AG W ALY G+ L G +++GLG+VG+ + R+
Sbjct: 108 LAIGLAIAAGRNVLQGDAATRAGYSGWRPALY-GTGLHGSVASVIGLGKVGQAILARLAG 166
Query: 555 FG-MNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
FG ++G DP V DQ + L++ +DY+ L PL+ TR+
Sbjct: 167 FGCARLLGVDPSVRLDQ-----VELVTLDEAVSTSDYVFLAVPLVSDTRH 211
>UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase, partial - Macaca mulatta
Length = 333
Score = 84.6 bits (200), Expect = 2e-15
Identities = 57/169 (33%), Positives = 84/169 (49%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+A +VRS ++ +E + LK+V RAGAGVD ID+D+A K V V N PG NA + E
Sbjct: 107 EACIVRS-DKLDEEFFNRAKNLKIVVRAGAGVDTIDLDAASKHHVVVENTPGQNANAVAE 165
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 560
+ L++ + R+ A+ +G E+ G TL + G G V R + F
Sbjct: 166 MVFALLIAMKRNHFDAT-------------SGREIRGSTLGLYGCGNVSRAMIEVSKGFA 212
Query: 561 MNIIGFDPFVSADQCAQFHCTXMELEDIWPL--ADYITLHTPLIESTRN 701
M +DPF+S +Q + C L D+ L D ++LH P T N
Sbjct: 213 MKCYSYDPFLSDEQIKE--CGAEPLHDLKELFKCDIVSLHVPATPQTIN 259
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 84.6 bits (200), Expect = 2e-15
Identities = 50/173 (28%), Positives = 87/173 (50%), Gaps = 2/173 (1%)
Frame = +3
Query: 183 MEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
+ + + A+++ + K DA LK++ R G G DNI V+SA K GV V N PGAN
Sbjct: 39 LSLASDAAVIIMTDMAFDKNWFDALPNLKLIARRGVGYDNIPVESATKHGVWVTNTPGAN 98
Query: 363 ALSACELTCRLMLVLARHVVPASTALKAGR--WDRALYTGSELAGKTLAILGLGRVGREV 536
A++ EL L+L + R V A+ +++ G A G L+GK + ++G G++ + +
Sbjct: 99 AIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASLMGHNLSGKIIGLIGYGQIAQNL 158
Query: 537 ATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
++ FG +++ + QF + + + +D I+LH P T
Sbjct: 159 EKILHGFGAHVLVYSRTKRETLYGQF----VSYDTLLAQSDIISLHIPATPET 207
>UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=4;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding -
Magnetospirillum gryphiswaldense
Length = 319
Score = 84.6 bits (200), Expect = 2e-15
Identities = 52/171 (30%), Positives = 86/171 (50%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
+ HD + + ++ +VL +L+VVG+ G G+D ID+ + G + G N
Sbjct: 51 LDGHDKAIT-ALERLNGDVLARLPRLRVVGKYGVGLDMIDLPAMSALGKKLGWTGGVNRR 109
Query: 369 SACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 548
S EL + L RHV A+ ++ G W + + G +L+ + + I+G G +G+++A +
Sbjct: 110 SVSELVIAATISLLRHVPAANQLVRDGGWRQLM--GRQLSQRVVGIVGCGHIGKDLAVLL 167
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFG ++ D D A M L+ + AD +TLH P ESTRN
Sbjct: 168 RAFGCRVLAHDIKAFPDFYAAHGVEPMGLDALLQQADVVTLHLPGDESTRN 218
>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 312
Score = 84.2 bits (199), Expect = 3e-15
Identities = 39/102 (38%), Positives = 61/102 (59%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
L++V GAG +N+DV +A ++G+ V +APG NA + + ++L LAR P + A++
Sbjct: 66 LEIVCAFGAGYENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALARGYAPLTGAVR 125
Query: 444 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNI 569
AGRW + L G L ++G+GR+GR VA R F M +
Sbjct: 126 AGRWHASRAARPTLTGAALGVIGMGRIGRLVAARAQGFDMTL 167
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 84.2 bits (199), Expect = 3e-15
Identities = 45/138 (32%), Positives = 70/138 (50%), Gaps = 2/138 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGV--KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 362
+P D ++ T V +AG +LK + G GVDN+D + + G+ + N PG
Sbjct: 88 VPQFDGWIIGD-DPATARVFEAGKAGRLKAAVKWGVGVDNVDFAACQRLGLPISNTPGMF 146
Query: 363 ALSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT 542
++ ++ LAR +KAG W ++ G LAGKT+A+ G G +GR A
Sbjct: 147 GREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AGISLAGKTVALAGFGDIGRNTAR 204
Query: 543 RMYAFGMNIIGFDPFVSA 596
R++A M I+ +DPF A
Sbjct: 205 RLFAAEMKIVAYDPFFKA 222
>UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family; n=2; Cyanobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase family -
Synechocystis sp. (strain PCC 6803)
Length = 318
Score = 83.8 bits (198), Expect = 4e-15
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 3/157 (1%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGV--KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
V+ T VL G KLK + + G GVD ID+ +A + G+ N P ++
Sbjct: 54 VIAGDDPFTARVLTIGKQGKLKALAKWGIGVDAIDLAAAKQLGILTSNTPNVFGDEVADV 113
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 563
+++LAR + A++ G W + G L GKT I+G+G +G+ +A R+ + G+
Sbjct: 114 AIGYLILLARELHCIDQAVRQGEWLKI--RGHSLRGKTAGIIGVGSIGQAIAVRLQSMGL 171
Query: 564 NIIGFDPF-VSADQCAQFHCTXMELEDIWPLADYITL 671
++G+DP +SAD C Q + L+D+ AD + L
Sbjct: 172 KLLGYDPHPISADFCEQTGLHPVPLQDVLQQADCLFL 208
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 83.8 bits (198), Expect = 4e-15
Identities = 48/155 (30%), Positives = 86/155 (55%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
++ + + K+VL+ +LK + G +DNIDV+ A +K + + N P A++ E T
Sbjct: 52 IIVGSEPLPKKVLETNPRLKTIACCGKHLDNIDVEYAQEKNIIIYNPPKGYAIAVAEFTV 111
Query: 390 RLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNI 569
L+L L R + +++G W + + G+ L GK + I+GLG+VG+ VA R+ FG++I
Sbjct: 112 GLILSLIRQIPYQDKEVRSGVWHKRI--GNLLHGKRVGIIGLGQVGKAVAERLLPFGVDI 169
Query: 570 IGFDPFVSADQCAQFHCTXMELEDIWPLADYITLH 674
DP V + +F +L+ + ++ IT+H
Sbjct: 170 AYNDPNVYSTTFQKF-----DLDKLIDWSNIITIH 199
>UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 325
Score = 83.8 bits (198), Expect = 4e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 2/169 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D ++VR ++ V++ V+DA + K V R G GVDNID+ +A + + V N P
Sbjct: 57 DVVLVRESS-VSRRVIDAMDRCKAVIRYGIGVDNIDMAAAAARRIAVANVPDYGTDEVST 115
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRALYTGS-ELAGKTLAILGLGRVGREVATRMYAF 557
T L L + R VV +++GRW + L G+TL ++G GR+ R + F
Sbjct: 116 QTVALALAVVRQVVSHDREVRSGRWSTGVIKPMYRLRGRTLGLIGYGRIARMTHEKFSGF 175
Query: 558 GM-NIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
G ++ DP Q +++DI AD I+LH PL TR+
Sbjct: 176 GFGRVLVNDPCPELPDGVQ----AADVDDICREADIISLHAPLTAQTRH 220
>UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia cepacia (strain ATCC 53795 /
AMMD)
Length = 320
Score = 83.8 bits (198), Expect = 4e-15
Identities = 50/145 (34%), Positives = 75/145 (51%), Gaps = 6/145 (4%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
+K++ A AG D++DV +A ++G+ V NAP A + T LML R ++
Sbjct: 73 VKIIANASAGYDHLDVAAARERGIVVSNAPDALTDCTADFTMLLMLAACRRASEYERIVR 132
Query: 444 AGRWDRAL----YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQC 605
AG W ++ G+ + GKTL I+G GR+GR VA R FGM I+ D P +
Sbjct: 133 AG-WGKSFGMTDMLGTRVNGKTLGIVGFGRIGRAVAQRARGFGMKIVYTDRQPAPPEVEA 191
Query: 606 AQFHCTXMELEDIWPLADYITLHTP 680
+C +L+ + P D +TLH P
Sbjct: 192 GARYCA--DLDTLLPQCDIVTLHVP 214
>UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Methanococcoides burtonii (strain DSM
6242)
Length = 317
Score = 83.8 bits (198), Expect = 4e-15
Identities = 46/170 (27%), Positives = 86/170 (50%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
+I N D L+ ++T+EV+ LK++ R G G+D ++ + K G+ V P A
Sbjct: 45 DIGNSDVLIA-GTERITEEVIKNAPNLKLISRVGVGLDGVNFELCNKYGIKVTYTPDAPT 103
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 545
++ EL ++L L+R + ++ G WDR Y G+ L GKT+ I G+GR+G+ +
Sbjct: 104 MAVAELCVGIILDLSRKISYTDRNVRKGVWDR--YMGNLLYGKTVGIFGMGRIGKSLVHL 161
Query: 546 MYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
+ +F + + D ++ + D+ +D I+++ PL + T
Sbjct: 162 LSSFNVKFLVNDITPDFSFGRLYNIEFVSKNDVLEKSDIISINIPLKKDT 211
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 83.4 bits (197), Expect = 5e-15
Identities = 46/175 (26%), Positives = 89/175 (50%), Gaps = 4/175 (2%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
I DA+ ++ +EVL A G KLKV+ GVD++D+ + + + + PG
Sbjct: 419 IKEADAIFCLLTDKIDEEVLSAAGSKLKVIATMSVGVDHLDLKAIKSRNIPIGYTPGVLT 478
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREV 536
+ ELT L+L +R ++ A+ A+ G W TG +++G + I+GLGR+G V
Sbjct: 479 DATAELTMALLLATSRRLIEANRAIYRGEWKAWCPTWMTGPKISGSNIGIVGLGRIGLRV 538
Query: 537 ATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
+ + +FG+ I + + ++L+++ +D++ + T L+ T++
Sbjct: 539 SEYLKSFGVAKILYTSRTEKPAATKLGAQKVDLDELLKESDFVIVTTALVPETKH 593
>UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3;
Mesorhizobium loti|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 341
Score = 83.4 bits (197), Expect = 5e-15
Identities = 53/162 (32%), Positives = 89/162 (54%), Gaps = 3/162 (1%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA-NALSACE 380
AL+ S T++T+ V+ A L+ + + G GVD+ID+D+A + G+ V + P + E
Sbjct: 60 ALMGASGTRITRRVMQALPDLRYISKYGIGVDSIDIDAATEHGILVSSTPNDFQIFTVSE 119
Query: 381 LTCRLMLVLARHVVPASTA-LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
LML +A+ + + ++ G W R L G+ L G T+ I+GLGR+GR VA R+ +
Sbjct: 120 HAVALMLAVAKQLGTWTPEFMRRGGW-RGLTHGATLRGATVGIVGLGRIGRGVAQRLSGW 178
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLH-TP 680
I+ +DPF+ A ++ + +D++TLH TP
Sbjct: 179 EARILAYDPFLKE---APPGIELVDFPTLVEQSDFLTLHATP 217
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 83.4 bits (197), Expect = 5e-15
Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 3/159 (1%)
Frame = +3
Query: 231 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLA 410
+ +E+ + LKVV G DNID+ +A +K V V N P + +LT LM+ A
Sbjct: 84 IDRELFEKSPNLKVVANLAVGFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAA 143
Query: 411 RHVVPASTALKAGR---WDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 581
R ++ A ++ G+ W L G+++ KT+ I+G+G +G A R F MNI+ +
Sbjct: 144 RRLIEADKYVREGKWKSWSPLLMAGTDIHHKTVGIIGMGSIGEAFARRAKGFDMNILYHN 203
Query: 582 PFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
+ LE++ +DY+ PL T+
Sbjct: 204 RSRKPEAEEVLGAKYASLEELLSQSDYVVCLAPLTPETK 242
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 83.4 bits (197), Expect = 5e-15
Identities = 56/173 (32%), Positives = 81/173 (46%), Gaps = 9/173 (5%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
V+ A +T+E+LD KL + G G D+ID++ +KGV ++N PG N+ ELT
Sbjct: 83 VICRANLITREMLDKEGKLMGLAIVGVGYDSIDIEGCKEKGVTLMNCPGENSQVVAELTL 142
Query: 390 RLMLVLARHVVPASTALKAGRWDRALYT-GSELAGKTLAILGLGRVGREVATRM-YAFGM 563
L L L R V L+AG ++ G L GK + ++G+ R A +AF
Sbjct: 143 SLTLALLRRVPELDRRLRAGETMLSINNLGRTLRGKVVGMVGISATARRAAAIFHHAFDC 202
Query: 564 NIIGFDPFVSADQCAQF-------HCTXMELEDIWPLADYITLHTPLIESTRN 701
I F P + + H L + PL D +TLH PL S+RN
Sbjct: 203 TIRTFSPTSPPTRWSPSHPSGPLPHTRHSSLSSMLPLIDILTLHCPLTPSSRN 255
>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Caldivirga
maquilingensis IC-167|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
maquilingensis IC-167
Length = 326
Score = 83.4 bits (197), Expect = 5e-15
Identities = 53/167 (31%), Positives = 86/167 (51%), Gaps = 2/167 (1%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DALVV +V VL + K+KV+ G D+ID+D+A ++G+ V P + +
Sbjct: 53 DALVVTIGDRVDDYVL-SNAKVKVIATYSVGYDHIDLDAATRRGIPVGYTPEVLVEAVAD 111
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRAL--YTGSELAGKTLAILGLGRVGREVATRMYA 554
L L++ LAR V+ +++G + + G+E+ GKTL ILGLG +G VA R A
Sbjct: 112 LAIGLIITLARRVIEGDRLVRSGEAYKVWGEFLGTEVWGKTLGILGLGNIGAAVARRAKA 171
Query: 555 FGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
F MN+I + ++L +++ +DY+ L L + T
Sbjct: 172 FNMNVIYWSRTRKPWIEVALGLRYVDLNELFRQSDYLVLTVALSKET 218
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 83.0 bits (196), Expect = 6e-15
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
++ QVT V + +L VG N+DV +A K+G+ V PG NA + E+
Sbjct: 64 LITELDQVTDSVFASVPELSFVGVCRGMPSNVDVAAASKRGIPVFYTPGRNAQAVAEMFI 123
Query: 390 RLMLVLARHVVPASTALKAGRWDR------ALYTGSELAGKTLAILGLGRVGREVATRMY 551
++ RH ++ LK G WD + G+EL GKT+ ++G G VG+ +A +
Sbjct: 124 GNVISFLRHTSASNQWLKDGEWDSDYLQAYVKFKGNELTGKTVGMIGFGAVGQRIAKLLT 183
Query: 552 AFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
AF I +DP++ D L+ ++ +D +++H P E T
Sbjct: 184 AFDCKIKYYDPYIQDDHPLY---EKASLKTVFSDSDIVSVHLPRTEET 228
>UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Beggiatoa sp. PS|Rep: D-3-phosphoglycerate dehydrogenase
- Beggiatoa sp. PS
Length = 302
Score = 83.0 bits (196), Expect = 6e-15
Identities = 49/173 (28%), Positives = 88/173 (50%), Gaps = 3/173 (1%)
Frame = +3
Query: 189 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 368
I + D ++++S ++ KE + A LK+V AG G+D+I +D K+G+ N P +A
Sbjct: 38 IEDKDVVILKSRIELDKEAIFAAKHLKLVVMAGIGLDHICLDELKKRGIAWFNIPDLSAR 97
Query: 369 SACELTCRLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILGLGRVGREVA 539
EL L L LAR + + L+ W R G L + I+G G++G+E+A
Sbjct: 98 GVAELVLGLTLSLARKICLGDSLLRNNEFKLWKRPELMGFNLQDRLFGIVGYGKIGKEMA 157
Query: 540 TRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
+ FGM + + S + + + T + +++ +D I++H PL + T+
Sbjct: 158 SVAKCFGMKVQVY-VRNSDHKTFEQNITPVTFQNLLKTSDVISIHVPLTDETK 209
>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
cellular organisms|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 330
Score = 82.6 bits (195), Expect = 8e-15
Identities = 48/150 (32%), Positives = 78/150 (52%), Gaps = 5/150 (3%)
Frame = +3
Query: 264 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCRLMLVLARHVVPASTALK 443
LK+V + G NID+ +A G+ V+N PG NA + E T +L R + AL+
Sbjct: 78 LKLVAVSRGGPINIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALR 137
Query: 444 AGRWDRALY----TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS-ADQCA 608
G W LY TG EL+ T+ ++G G +G +V + AFG +++ DP+V + +
Sbjct: 138 KGEWRGDLYRADRTGRELSEMTVGVIGYGNIGTKVVRLLRAFGCHVLVSDPYVQLSAEDR 197
Query: 609 QFHCTXMELEDIWPLADYITLHTPLIESTR 698
+ L+++ +D +TLH + E TR
Sbjct: 198 NAGVELVALDNLLARSDVVTLHPRVTEETR 227
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 82.6 bits (195), Expect = 8e-15
Identities = 43/128 (33%), Positives = 71/128 (55%), Gaps = 1/128 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 377
D L +RS T+VT+ V++A G KL VG G + +D+D+ + GV NAP +N S
Sbjct: 65 DLLGIRSRTRVTRRVVEACGDKLHAVGAFCIGTNQMDLDALAEAGVPAFNAPYSNTRSVV 124
Query: 378 ELTCRLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 557
EL ++ LAR + +T + G W ++ E+ G+ L I+G G +G++++ A
Sbjct: 125 ELVMAEIIALARRLGDRNTQMHNGVWRKSAIGSHEIRGRRLGIIGYGNIGQQLSVVAEAM 184
Query: 558 GMNIIGFD 581
GM + +D
Sbjct: 185 GMQVFFYD 192
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 82.6 bits (195), Expect = 8e-15
Identities = 50/172 (29%), Positives = 87/172 (50%), Gaps = 6/172 (3%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
+AL+V + +T+ LD L+V+G G++++ + S +G+ ++N G + +
Sbjct: 61 EALIVLLSEPLTEADLDLCPNLRVIGTYSVGINHLPITSCQSRGIRIVNTQGVLTDATAD 120
Query: 381 LTCRLMLVLARHVVPASTALKAGRWD---RALYTGSELAGKTLAILGLGRVGREVATRMY 551
L L+L L R V +++G W L G+ L GKT ILG G +GR A R++
Sbjct: 121 LALTLLLSLTRRVREGEALVRSGHWKGWAPDLLLGTGLTGKTCGILGSGPIGRAFARRVW 180
Query: 552 AFGMNIIGFDPFVSADQCAQFH---CTXMELEDIWPLADYITLHTPLIESTR 698
A GM +I F + F + L+++ +D ++LH PL ++TR
Sbjct: 181 AIGMKVI-FWNREGNQKPVDFGVDIAARLPLDELLRQSDVLSLHCPLTDTTR 231
>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
tuberculosis
Length = 326
Score = 82.6 bits (195), Expect = 8e-15
Identities = 53/171 (30%), Positives = 87/171 (50%), Gaps = 6/171 (3%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
D LVV S + V V + G L+VV N+D+ A G+ V++ P NA + E
Sbjct: 56 DVLVVESDS-VGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAE 112
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDR------ALYTGSELAGKTLAILGLGRVGREVAT 542
+T L+L +ARH++PA +++G R + G+E+AG T ++GLG VGR V
Sbjct: 113 MTVALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRW 172
Query: 543 RMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
R+ G+ +I DP+ D L+++ AD +++H + + T
Sbjct: 173 RLSGLGLRVIAHDPY--RDDAGH------SLDELLAEADIVSMHAAVTDDT 215
>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 274
Score = 82.6 bits (195), Expect = 8e-15
Identities = 50/171 (29%), Positives = 89/171 (52%), Gaps = 6/171 (3%)
Frame = +3
Query: 207 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 386
+V ++ +VLD L+++G AGV+++D ++ K+G+G++ PG + +S E
Sbjct: 10 IVFLDRATLSGDVLDQLPHLELIGVPAAGVNHLDTETCRKRGIGIVACPGYSTISVPEHA 69
Query: 387 CRLMLVLARHVVPASTALKAGRWDRA------LYTGSELAGKTLAILGLGRVGREVATRM 548
LML L R+++P + AG W + L+ +L G TL I+G G G+ +A
Sbjct: 70 FALMLALRRNLMPYWHDVYAGGWSGSPTFYAELHPIQDLHGSTLGIVGAGHGGKRLAELA 129
Query: 549 YAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFGM ++ F + + + +++ AD I+LH PL + TR+
Sbjct: 130 RAFGMRVL----FAERKRASCVRDGYVAFDEVLREADTISLHCPLTDETRH 176
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 82.6 bits (195), Expect = 8e-15
Identities = 48/127 (37%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Frame = +3
Query: 204 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 383
ALV + V+DA L+ + G D+IDV A +G+ V P + +L
Sbjct: 82 ALVCFPYDVIDAGVMDAAPDLETIATYSVGYDHIDVAHARGRGITVGYTPDVLTDATADL 141
Query: 384 TCRLMLVLARHVVPASTALKAGRWDRAL----YTGSELAGKTLAILGLGRVGREVATRMY 551
T LML L R V ++AGRW + Y G+++ GKTL ILG+GR+G VA R
Sbjct: 142 TMALMLDLLRRVTEGDRIIRAGRWRQIYGADDYLGTDVGGKTLGILGMGRIGSRVAKRAA 201
Query: 552 AFGMNII 572
AFGM +I
Sbjct: 202 AFGMKVI 208
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 82.2 bits (194), Expect = 1e-14
Identities = 47/174 (27%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +3
Query: 186 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 365
E+ D + + E + +LKVV G DNID+ A K+GV V + PG
Sbjct: 41 ELEEADGVFTNLTDRFDVEAFERAKRLKVVSTMAVGYDNIDIKEATKRGVSVGHTPGVLT 100
Query: 366 LSACELTCRLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREV 536
+ +LT L++ R + + ++ +W + TG + G TL I+G+GR+G+ V
Sbjct: 101 EATADLTFALLMATGRRLRESIDYVRNDQWKSWGPFMLTGQAIYGTTLGIIGMGRIGQAV 160
Query: 537 ATRMYAFGMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTR 698
A R F M ++ + + + T L+ + +DY+ L P + TR
Sbjct: 161 AKRAKGFNMTLLYHNRSRNEQAEKELGATYCSLDHLLARSDYVVLLAPSTDETR 214
>UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Actinomycetales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 326
Score = 82.2 bits (194), Expect = 1e-14
Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 1/168 (0%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DALVV+ A +V ++LDA ++ VGR G GVD +DVD+ +GV V N P S +
Sbjct: 46 DALVVQYA-RVDADLLDALPTVRAVGRYGVGVDTVDVDACTARGVAVCNVPDYGTESVSD 104
Query: 381 LTCRLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGREVATRMYAF 557
L L AR + ++AG + A L + G+ ++GLG +G A +
Sbjct: 105 HAIALALAAARRIAWMDRRVRAGAGELAPLRPVHQFGGRVFGVVGLGLIGAATARKAAGL 164
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
G ++ D A + L+D+ A ++LH PL E TR+
Sbjct: 165 GYRVVATDA-RRAPGTTVDGVEVVTLDDLLARAHVVSLHVPLTEGTRH 211
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 82.2 bits (194), Expect = 1e-14
Identities = 58/173 (33%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRA--GAGVDNIDVDSAGKKGVGVINAPGANALSA 374
D L++ A +V L AG+ V A G+D+ID+D+ +G+ + N PG + +
Sbjct: 47 DVLLLSPAVRVDAAFL-AGLPASVGALATYSVGLDHIDLDAVRARGLPMFNTPGILSNAV 105
Query: 375 CELTCRLMLVLARHVVPASTALKAGRWD---RALYTGSELAGKTLAILGLGRVGREVATR 545
+ L+L R + A+ L+ GRW + G ELAG+TL I GLG +GR VA R
Sbjct: 106 ADQAMLLLLAATRRMAEATALLREGRWTDLWSSHILGVELAGRTLGIYGLGDIGRRVARR 165
Query: 546 MYAFGMNIIGFDPFVSADQC-AQFHCTXMELEDIWPLADYITLHTPLIESTRN 701
AFGM ++ + + D+ A F T E+ AD + L P TRN
Sbjct: 166 ATAFGMRLVYHNRRRAVDEAGATFAAT---AEEFLASADILLLAAPSTGETRN 215
>UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1;
Oceanobacillus iheyensis|Rep: 2-ketogluconate reductase
- Oceanobacillus iheyensis
Length = 324
Score = 81.4 bits (192), Expect = 2e-14
Identities = 45/166 (27%), Positives = 80/166 (48%), Gaps = 4/166 (2%)
Frame = +3
Query: 210 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 389
++ S +V +LD LK+V G DN++++ K+G+ N P + +
Sbjct: 48 IIGSKLRVDGHLLDQAPHLKIVTNISVGYDNLEIEELTKRGIMATNTPDVLTDTVADTVF 107
Query: 390 RLMLVLARHVVPASTALKAGRWDRAL---YTGSELAGKTLAILGLGRVGREVATRM-YAF 557
L+L +R + +K GRWD + G ++ KTL I+G+GR+G VA R Y F
Sbjct: 108 GLLLATSRRICELDQYVKLGRWDENIGEHLFGVDVHHKTLGIIGMGRIGLAVAERAHYGF 167
Query: 558 GMNIIGFDPFVSADQCAQFHCTXMELEDIWPLADYITLHTPLIEST 695
M I+ + + + T LE++ ++D++ + PL+ T
Sbjct: 168 KMKIVYHNRSTHSYAEKNINATYASLEELLTVSDFVLVMAPLVPET 213
>UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; uncultured bacterium
MedeBAC49C08|Rep: Predicted D-isomer specific
2-hydroxyacid dehydrogenase family protein - uncultured
bacterium MedeBAC49C08
Length = 395
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/180 (31%), Positives = 90/180 (50%), Gaps = 15/180 (8%)
Frame = +3
Query: 201 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 380
DA+++RS E+ + +K + RAGAGV+NI V+ K G+ V N PGANA + E
Sbjct: 34 DAIILRSHKLQMSEIPSS---VKAIVRAGAGVNNIPVEECSKIGIPVFNTPGANANAVKE 90
Query: 381 LTCRLMLVLARHVVP-----------ASTALKAG-RWDRALYTGSELAGKTLAILGLGRV 524
+ +L+ +R + + LKA + + G EL L ++G+G +
Sbjct: 91 MVLAALLMSSRGIFDGVKFVHGIEDVSKENLKAHIESGKKSFKGRELKDGCLGVVGMGAI 150
Query: 525 GREVATRMYAFGMNIIGFDPFVSADQCAQF--HCTXME-LEDIWPLADYITLHTPLIEST 695
G +VA GM +IGFDP ++ + E +E+I+ +DY+TLH P E T
Sbjct: 151 GAKVAEMGVMLGMRVIGFDPQITVEAAWALPNEVERKETIEEIFKESDYVTLHVPANEHT 210
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 710,709,108
Number of Sequences: 1657284
Number of extensions: 15489495
Number of successful extensions: 79610
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 68340
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 78408
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55785129165
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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