Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30390
(729 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 245 1e-64
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 245 1e-64
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 244 3e-64
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 244 3e-64
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 227 3e-59
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 224 2e-58
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 224 2e-58
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 224 2e-58
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 224 2e-58
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 213 7e-55
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 213 7e-55
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 213 7e-55
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 213 7e-55
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 213 7e-55
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 212 1e-54
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 189 8e-48
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 186 9e-47
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 186 9e-47
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 186 9e-47
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 101 2e-21
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 99 8e-21
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 99 8e-21
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 99 1e-20
BC025719-1|AAH25719.1| 390|Homo sapiens matrix metallopeptidase... 32 1.8
AL691432-6|CAM12835.1| 390|Homo sapiens matrix metallopeptidase... 32 1.8
AJ005256-1|CAB38176.1| 390|Homo sapiens MMP-23 protein. 32 1.8
AF057062-1|AAC62618.1| 249|Homo sapiens metalloprotease mmp21/2... 32 1.8
AF057061-1|AAC62617.1| 265|Homo sapiens metalloprotease mmp21/2... 32 1.8
AF056200-1|AAC62616.1| 390|Homo sapiens metalloprotease mmp21/2... 32 1.8
AF055334-3|AAC63529.1| 250|Homo sapiens metalloprotease isoform... 32 1.8
AF055334-2|AAC63528.1| 266|Homo sapiens metalloprotease isoform... 32 1.8
AF055334-1|AAC63527.1| 390|Homo sapiens metalloprotease isoform... 32 1.8
AB031068-1|BAA92769.1| 390|Homo sapiens MIFR/Femalysin protein. 32 1.8
AB010961-1|BAA24833.1| 390|Homo sapiens MIFR-1 protein. 32 1.8
BT007435-1|AAP36103.1| 441|Homo sapiens G protein-coupled recep... 32 2.4
BC125081-1|AAI25082.1| 486|Homo sapiens G protein-coupled recep... 32 2.4
BC125080-1|AAI25081.1| 486|Homo sapiens G protein-coupled recep... 32 2.4
BC110848-1|AAI10849.1| 486|Homo sapiens G protein-coupled recep... 32 2.4
BC016860-1|AAH16860.2| 448|Homo sapiens GPRC5C protein protein. 32 2.4
AK075397-1|BAC11595.1| 441|Homo sapiens protein ( Homo sapiens ... 32 2.4
AJ276102-1|CAC00633.1| 441|Homo sapiens GPRC5C protein. 32 2.4
AF207989-1|AAF72870.1| 441|Homo sapiens orphan G-protein couple... 32 2.4
BC034469-1|AAH34469.1| 849|Homo sapiens coiled-coil domain cont... 30 7.4
AK001648-1|BAA91808.1| 849|Homo sapiens protein ( Homo sapiens ... 30 7.4
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 245 bits (599), Expect = 1e-64
Identities = 109/225 (48%), Positives = 149/225 (66%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ Y A V+ AHA+ YH Y+ +++ +Q G +++S +
Sbjct: 1083 VKDPGWAPYRIAHTVIKAHARVYHTYDEKYRQEQKGVISLSLSTH 1127
Score = 239 bits (585), Expect = 7e-63
Identities = 108/227 (47%), Positives = 153/227 (67%), Gaps = 1/227 (0%)
Frame = +3
Query: 45 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 224
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 225 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 404
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 405 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 585 -ILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ N Y+ N++ AHA+A+HLYN+ ++ QGG ITIS++
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSD 1601
Score = 198 bits (484), Expect = 1e-50
Identities = 95/229 (41%), Positives = 139/229 (60%), Gaps = 1/229 (0%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 215
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 216 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 395
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 396 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 575
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 576 KAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
P ++ + ++ A VL AHA+ +H YN+ + +Q G GI ++++
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSD 604
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/154 (29%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = +3
Query: 261 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 437
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 438 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGTYL 617
FA+ F DYA + +FGD V W T ++ E+ E +A L
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 618 CAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ + AH KAY +Y+ + QGG+ + + A
Sbjct: 193 --QTLSDAHRKAYEIYHESYA-FQGGKLSVVLRA 223
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 245 bits (599), Expect = 1e-64
Identities = 109/225 (48%), Positives = 149/225 (66%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 514
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ Y A V+ AHA+ YH Y+ +++ +Q G +++S +
Sbjct: 515 VKDPGWAPYRIAHTVIKAHARVYHTYDEKYRQEQKGVISLSLSTH 559
Score = 205 bits (500), Expect = 1e-52
Identities = 90/181 (49%), Positives = 125/181 (69%)
Frame = +3
Query: 45 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 224
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 808 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 866
Query: 225 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 404
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926
Query: 405 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 927 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
Query: 585 I 587
+
Sbjct: 987 V 987
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/31 (38%), Positives = 21/31 (67%)
Frame = +3
Query: 630 VLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
VL AHA+ +H YN+ + +Q G GI ++++
Sbjct: 6 VLKAHARTWHHYNSHHRPQQQGHVGIVLNSD 36
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 244 bits (597), Expect = 3e-64
Identities = 109/225 (48%), Positives = 149/225 (66%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ Y A V+ AHA+ YH Y+ +++ +Q G +++S +
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTH 1127
Score = 239 bits (585), Expect = 7e-63
Identities = 108/227 (47%), Positives = 153/227 (67%), Gaps = 1/227 (0%)
Frame = +3
Query: 45 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 224
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 225 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 404
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 405 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 585 -ILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ N Y+ N++ AHA+A+HLYN+ ++ QGG ITIS++
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSD 1601
Score = 198 bits (484), Expect = 1e-50
Identities = 95/229 (41%), Positives = 139/229 (60%), Gaps = 1/229 (0%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 215
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 216 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 395
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 396 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 575
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 576 KAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
P ++ + ++ A VL AHA+ +H YN+ + +Q G GI ++++
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSD 604
Score = 63.3 bits (147), Expect = 9e-10
Identities = 46/154 (29%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = +3
Query: 261 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 437
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 438 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGTYL 617
FA+ F DYA + +FGD V W T ++ E+ E +A L
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 618 CAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ + AH KAY +Y+ + QGG+ I + A
Sbjct: 193 --QTLSDAHRKAYEIYHESYA-FQGGKLSIVLRA 223
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 244 bits (597), Expect = 3e-64
Identities = 109/225 (48%), Positives = 149/225 (66%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ Y A V+ AHA+ YH Y+ +++ +Q G +++S +
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTH 1127
Score = 239 bits (585), Expect = 7e-63
Identities = 108/227 (47%), Positives = 153/227 (67%), Gaps = 1/227 (0%)
Frame = +3
Query: 45 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 224
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 225 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 404
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 405 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 585 -ILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ N Y+ N++ AHA+A+HLYN+ ++ QGG ITIS++
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSD 1601
Score = 198 bits (484), Expect = 1e-50
Identities = 95/229 (41%), Positives = 139/229 (60%), Gaps = 1/229 (0%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 215
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 216 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 395
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 396 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 575
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 576 KAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
P ++ + ++ A VL AHA+ +H YN+ + +Q G GI ++++
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSD 604
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/154 (29%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = +3
Query: 261 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 437
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 438 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPILNATAIGTYL 617
FA+ F DYA + +FGD V W T ++ E+ E +A L
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 618 CAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ + AH KAY +Y+ + QGG+ + + A
Sbjct: 193 --QTLSDAHRKAYEIYHESYA-FQGGKLSVVLRA 223
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 227 bits (555), Expect = 3e-59
Identities = 100/227 (44%), Positives = 150/227 (66%), Gaps = 2/227 (0%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F G +++YQ EGAW++DGKG +IWD TH+ V T D+A + Y+ V+ D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGF-ANEINEAGVDYYNRLINEMLKYGITPMITLFHW 404
+ ++REL ++ YRFSLSW R+LP+G A ++N+ G+++Y+ LI+ +L ITP++TL HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 405 DLPQKLQ-ELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKA 581
DLPQ LQ + GG+ N + +F DYA + + FGDRVKHWIT ++PR + +GY + H A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 582 PILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
P L G Y A +++ AHAK +H YN ++ KQ G GI+++ +
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKTWHSYNTTWRSKQQGLVGISLNCD 263
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 224 bits (548), Expect = 2e-58
Identities = 107/244 (43%), Positives = 153/244 (62%), Gaps = 16/244 (6%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 179
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 180 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 353
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 354 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 530
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 531 NEPREICYEGYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGIT 710
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIA 297
Query: 711 ISAN 722
+S++
Sbjct: 298 LSSH 301
Score = 101 bits (243), Expect = 2e-21
Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 10/235 (4%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 212
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 690
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
T TY N+L AHA A+H+YN +F+ Q G+ I + A+
Sbjct: 691 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQAD 733
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 224 bits (548), Expect = 2e-58
Identities = 107/244 (43%), Positives = 153/244 (62%), Gaps = 16/244 (6%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 179
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 180 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 353
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 354 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 530
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 531 NEPREICYEGYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGIT 710
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIA 297
Query: 711 ISAN 722
+S++
Sbjct: 298 LSSH 301
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 224 bits (548), Expect = 2e-58
Identities = 107/244 (43%), Positives = 153/244 (62%), Gaps = 16/244 (6%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 179
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 180 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 353
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 354 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 530
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 531 NEPREICYEGYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGIT 710
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIA 297
Query: 711 ISAN 722
+S++
Sbjct: 298 LSSH 301
Score = 101 bits (243), Expect = 2e-21
Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 10/235 (4%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 212
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 690
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
T TY N+L AHA A+H+YN +F+ Q G+ I + A+
Sbjct: 691 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQAD 733
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 224 bits (548), Expect = 2e-58
Identities = 107/244 (43%), Positives = 153/244 (62%), Gaps = 16/244 (6%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 179
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 180 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 353
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 354 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 530
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 531 NEPREICYEGYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGIT 710
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIA 297
Query: 711 ISAN 722
+S++
Sbjct: 298 LSSH 301
Score = 101 bits (243), Expect = 2e-21
Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 10/235 (4%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 212
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 690
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
T TY N+L AHA A+H+YN +F+ Q G+ I + A+
Sbjct: 691 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQAD 733
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 213 bits (519), Expect = 7e-55
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ G Y A N++ AHA+++H Y++ F+ KQ G +++ A
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 213 bits (519), Expect = 7e-55
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ G Y A N++ AHA+++H Y++ F+ KQ G +++ A
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 213 bits (519), Expect = 7e-55
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ G Y A N++ AHA+++H Y++ F+ KQ G +++ A
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 213 bits (519), Expect = 7e-55
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ G Y A N++ AHA+++H Y++ F+ KQ G +++ A
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 213 bits (519), Expect = 7e-55
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ G Y A N++ AHA+++H Y++ F+ KQ G +++ A
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 212 bits (517), Expect = 1e-54
Identities = 97/224 (43%), Positives = 141/224 (62%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 408 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 587
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 588 LNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISA 719
+ G Y A N++ AHA+++H Y++ F+ KQ G +++ A
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFA 226
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 189 bits (461), Expect = 8e-48
Identities = 92/216 (42%), Positives = 133/216 (61%), Gaps = 16/216 (7%)
Frame = +3
Query: 39 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 179
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 180 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 353
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 354 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 530
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 531 NEPREICYEGYGSVHKAPILNATAIGTYLCAKNVLI 638
+ P + + GY + AP + + YL A N+L+
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 186 bits (452), Expect = 9e-47
Identities = 85/226 (37%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 408 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 585 ILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
Y N++ AH+K +H YN F+ Q G IT+ ++
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSH 303
Score = 116 bits (280), Expect = 7e-26
Identities = 60/175 (34%), Positives = 99/175 (56%), Gaps = 5/175 (2%)
Frame = +3
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRL--- 697
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ I N + TY A N+L+AHA A+ LY+ +F+ Q G +++ A+
Sbjct: 698 -------SDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHAD 745
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 186 bits (452), Expect = 9e-47
Identities = 85/226 (37%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 408 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 585 ILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
Y N++ AH+K +H YN F+ Q G IT+ ++
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSH 303
Score = 116 bits (280), Expect = 7e-26
Identities = 60/175 (34%), Positives = 99/175 (56%), Gaps = 5/175 (2%)
Frame = +3
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRL--- 697
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ I N + TY A N+L+AHA A+ LY+ +F+ Q G +++ A+
Sbjct: 698 -------SDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHAD 745
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 186 bits (452), Expect = 9e-47
Identities = 85/226 (37%), Positives = 133/226 (58%), Gaps = 1/226 (0%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 407
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 408 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 584
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 585 ILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
Y N++ AH+K +H YN F+ Q G IT+ ++
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSH 303
Score = 116 bits (280), Expect = 7e-26
Identities = 60/175 (34%), Positives = 99/175 (56%), Gaps = 5/175 (2%)
Frame = +3
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRL--- 697
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
+ I N + TY A N+L+AHA A+ LY+ +F+ Q G +++ A+
Sbjct: 698 -------SDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHAD 745
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 101 bits (243), Expect = 2e-21
Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 10/235 (4%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 212
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 303
Query: 213 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 392
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 304 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 363
Query: 393 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 557
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 364 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 417
Query: 558 GYGSVHKAPILNATAIGTYLCAKNVLIAHAKAYHLYNNEFKDKQGGQCGITISAN 722
T TY N+L AHA A+H+YN +F+ Q G+ I + A+
Sbjct: 418 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQAD 460
Score = 39.1 bits (87), Expect = 0.016
Identities = 15/28 (53%), Positives = 20/28 (71%)
Frame = +3
Query: 639 AHAKAYHLYNNEFKDKQGGQCGITISAN 722
AHAK +HLYN F+ QGGQ I +S++
Sbjct: 1 AHAKVWHLYNTSFRPTQGGQVSIALSSH 28
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99 bits (238), Expect = 8e-21
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 332
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99 bits (238), Expect = 8e-21
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 332
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99.1 bits (236), Expect = 1e-20
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 48 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 227
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 228 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 332
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC025719-1|AAH25719.1| 390|Homo sapiens matrix metallopeptidase
23B protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AL691432-6|CAM12835.1| 390|Homo sapiens matrix metallopeptidase
23B protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AJ005256-1|CAB38176.1| 390|Homo sapiens MMP-23 protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AF057062-1|AAC62618.1| 249|Homo sapiens metalloprotease mmp21/22C
protein.
Length = 249
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 210 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 247
>AF057061-1|AAC62617.1| 265|Homo sapiens metalloprotease mmp21/22B
protein.
Length = 265
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 226 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 263
>AF056200-1|AAC62616.1| 390|Homo sapiens metalloprotease mmp21/22A
protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AF055334-3|AAC63529.1| 250|Homo sapiens metalloprotease isoform C
protein.
Length = 250
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 210 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 247
>AF055334-2|AAC63528.1| 266|Homo sapiens metalloprotease isoform B
protein.
Length = 266
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 226 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 263
>AF055334-1|AAC63527.1| 390|Homo sapiens metalloprotease isoform A
protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AB031068-1|BAA92769.1| 390|Homo sapiens MIFR/Femalysin protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AB010961-1|BAA24833.1| 390|Homo sapiens MIFR-1 protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 516 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 620
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>BT007435-1|AAP36103.1| 441|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>BC125081-1|AAI25082.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC125080-1|AAI25081.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC110848-1|AAI10849.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC016860-1|AAH16860.2| 448|Homo sapiens GPRC5C protein protein.
Length = 448
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 395 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 445
>AK075397-1|BAC11595.1| 441|Homo sapiens protein ( Homo sapiens
cDNA PSEC0087 fis, clone PLACE1001022, highly similar to
G protein-coupled receptor, family C, group 5, member C
isoform ).
Length = 441
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>AJ276102-1|CAC00633.1| 441|Homo sapiens GPRC5C protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>AF207989-1|AAF72870.1| 441|Homo sapiens orphan G-protein coupled
receptor protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.4
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 57 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 209
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>BC034469-1|AAH34469.1| 849|Homo sapiens coiled-coil domain
containing 87 protein.
Length = 849
Score = 30.3 bits (65), Expect = 7.4
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 31 PSSREGFRMTSSSGLPPPPTR 93
PS REG+R+ GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333
>AK001648-1|BAA91808.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ10786 fis, clone NT2RP4000480. ).
Length = 849
Score = 30.3 bits (65), Expect = 7.4
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 31 PSSREGFRMTSSSGLPPPPTR 93
PS REG+R+ GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,371,269
Number of Sequences: 237096
Number of extensions: 2175256
Number of successful extensions: 5204
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 4936
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5168
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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