Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30312
(750 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s... 277 3e-73
UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH... 271 1e-71
UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 271 1e-71
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC... 219 8e-56
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 211 1e-53
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;... 209 6e-53
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 206 6e-52
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 197 2e-49
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 197 3e-49
UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 compone... 176 5e-43
UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut... 171 2e-41
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 170 3e-41
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 170 3e-41
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 169 6e-41
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 168 1e-40
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 167 3e-40
UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E... 166 6e-40
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 164 2e-39
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 162 7e-39
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 161 1e-38
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 158 1e-37
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 157 2e-37
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 155 8e-37
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 155 1e-36
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 153 6e-36
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte... 152 8e-36
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 151 1e-35
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 150 3e-35
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 150 4e-35
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 149 5e-35
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 149 5e-35
UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000... 149 1e-34
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 149 1e-34
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E... 148 2e-34
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 148 2e-34
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 146 4e-34
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 145 1e-33
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 144 2e-33
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 144 2e-33
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 144 2e-33
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 144 3e-33
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 140 3e-32
UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;... 138 1e-31
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p... 137 2e-31
UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 137 2e-31
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 137 3e-31
UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo... 137 3e-31
UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 136 7e-31
UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 135 1e-30
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 135 1e-30
UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 134 2e-30
UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,... 134 2e-30
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 132 9e-30
UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 131 2e-29
UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil... 131 2e-29
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 129 6e-29
UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 128 1e-28
UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdello... 128 2e-28
UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 128 2e-28
UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 127 3e-28
UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 125 1e-27
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 124 2e-27
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 123 4e-27
UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s... 122 7e-27
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone... 121 2e-26
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 121 2e-26
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 120 4e-26
UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 116 5e-25
UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma... 115 1e-24
UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 108 1e-22
UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ... 107 3e-22
UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ... 104 2e-21
UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh... 103 5e-21
UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;... 81 2e-14
UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lu... 77 4e-13
UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura... 70 7e-11
UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_UPI0000E46CA4 Cluster: PREDICTED: hypothetical protein,... 39 0.15
UniRef50_Q9KJ66 Cluster: Irb5; n=1; Vibrio cholerae|Rep: Irb5 - ... 37 0.46
UniRef50_A3Z1Y0 Cluster: Serine protease, subtilase family prote... 36 1.4
UniRef50_Q1MRZ5 Cluster: Hyphotheical protein; n=1; Lawsonia int... 35 2.5
UniRef50_A5DBM7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.5
UniRef50_Q14197 Cluster: Immature colon carcinoma transcript 1 p... 33 7.5
UniRef50_Q2NB23 Cluster: Protein-tyrosine-phosphatase; n=6; Alph... 33 9.9
UniRef50_Q029Y8 Cluster: NHL repeat containing protein; n=2; Bac... 33 9.9
UniRef50_A5V064 Cluster: Putative uncharacterized protein; n=2; ... 33 9.9
UniRef50_Q9ST86 Cluster: CAA303711.1 protein; n=2; Oryza sativa|... 33 9.9
>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1054
Score = 277 bits (678), Expect = 3e-73
Identities = 132/181 (72%), Positives = 152/181 (83%), Gaps = 1/181 (0%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + + KR +LARL RST FE+FLA+KWSSEKRFGLEGCE+LIPA+K +ID S+
Sbjct: 240 PGIMRFTDADKRTLLARLIRSTRFEDFLARKWSSEKRFGLEGCEVLIPALKTIIDESSAA 299
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDDGSGDVKYHLGTYIERLNR 473
GV+S+IMGMPHRGRLNVLANV RK L Q+F QF LEA D+GSGDVKYHLG Y ER+NR
Sbjct: 300 GVDSVIMGMPHRGRLNVLANVIRKDLDQIFCQFDPKLEAADEGSGDVKYHLGMYHERINR 359
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
T+KNI L++ ANPSHLEAVDPVV GKT+AEQFYRGD EGKKVMSIL+HGDAAFAGQGVV
Sbjct: 360 KTDKNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDVEGKKVMSILIHGDAAFAGQGVV 419
Query: 654 F 656
+
Sbjct: 420 Y 420
Score = 60.9 bits (141), Expect = 3e-08
Identities = 23/36 (63%), Positives = 31/36 (86%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LREI+ RLE AYC +IG+EFMFIN+++QC WIR ++
Sbjct: 202 LREIIRRLEMAYCGHIGVEFMFINNVDQCQWIRNKI 237
Score = 50.0 bits (114), Expect = 6e-05
Identities = 19/26 (73%), Positives = 23/26 (88%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQI 732
+ET HLS+LP+YTTHGTIH V NNQ+
Sbjct: 420 YETFHLSELPSYTTHGTIHVVVNNQV 445
>UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH
protein - Homo sapiens (Human)
Length = 640
Score = 271 bits (665), Expect = 1e-71
Identities = 127/181 (70%), Positives = 151/181 (83%), Gaps = 1/181 (0%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + + ++KR +LARL RST FE FL +KWSSEKRFGLEGCE+LIPA+K +ID S++
Sbjct: 147 PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN 206
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDDGSGDVKYHLGTYIERLNR 473
GV+ +IMGMPHRGRLNVLANV RK L Q+F QF + LEA D+GSGDVKYHLG Y R+NR
Sbjct: 207 GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR 266
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
VT++NI L++ ANPSHLEA DPVV GKT+AEQFY GD EGKKVMSILLHGDAAFAGQG+V
Sbjct: 267 VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIV 326
Query: 654 F 656
+
Sbjct: 327 Y 327
Score = 64.5 bits (150), Expect = 3e-09
Identities = 26/35 (74%), Positives = 30/35 (85%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQR 106
LREI+ RLE AYC +IG+EFMFIN LEQC WIRQ+
Sbjct: 109 LREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQK 143
Score = 62.5 bits (145), Expect = 1e-08
Identities = 25/32 (78%), Positives = 28/32 (87%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET HLSDLP+YTTHGT+H V NNQIGFTT P
Sbjct: 327 YETFHLSDLPSYTTHGTVHVVVNNQIGFTTDP 358
>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=77; Eumetazoa|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Homo sapiens (Human)
Length = 1002
Score = 271 bits (665), Expect = 1e-71
Identities = 127/181 (70%), Positives = 151/181 (83%), Gaps = 1/181 (0%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + + ++KR +LARL RST FE FL +KWSSEKRFGLEGCE+LIPA+K +ID S++
Sbjct: 241 PGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSEN 300
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDDGSGDVKYHLGTYIERLNR 473
GV+ +IMGMPHRGRLNVLANV RK L Q+F QF + LEA D+GSGDVKYHLG Y R+NR
Sbjct: 301 GVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINR 360
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
VT++NI L++ ANPSHLEA DPVV GKT+AEQFY GD EGKKVMSILLHGDAAFAGQG+V
Sbjct: 361 VTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIV 420
Query: 654 F 656
+
Sbjct: 421 Y 421
Score = 64.5 bits (150), Expect = 3e-09
Identities = 26/35 (74%), Positives = 30/35 (85%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQR 106
LREI+ RLE AYC +IG+EFMFIN LEQC WIRQ+
Sbjct: 203 LREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQK 237
Score = 62.5 bits (145), Expect = 1e-08
Identities = 25/32 (78%), Positives = 28/32 (87%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET HLSDLP+YTTHGT+H V NNQIGFTT P
Sbjct: 421 YETFHLSDLPSYTTHGTVHVVVNNQIGFTTDP 452
>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG33791-PC, isoform C - Apis mellifera
Length = 980
Score = 219 bits (534), Expect = 8e-56
Identities = 101/181 (55%), Positives = 132/181 (72%), Gaps = 1/181 (0%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + AD ++ I + ++ FE FLA+K+ +EKRFGLEGCE IP+M Q ++ S +
Sbjct: 205 PGAWDLPADHRKFIWMNIMKAVTFEGFLARKFPTEKRFGLEGCESFIPSMNQCLETSAEH 264
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRV 476
GVES+++GM HRGRLN L NVC KPLHQL TQF + E GSGDVKYHLGT+ ER+
Sbjct: 265 GVESVVIGMAHRGRLNTLINVCMKPLHQLLTQFHSIALEGFGSGDVKYHLGTHAERMLER 324
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNE-GKKVMSILLHGDAAFAGQGVV 653
+ K IR+A+ ANPSHLEA+DPVV G+ RAEQ + D E GKK ++ L+HGDAAF+GQG+V
Sbjct: 325 SQKQIRVAMMANPSHLEAIDPVVVGRVRAEQVEKNDAEFGKKSVAFLVHGDAAFSGQGIV 384
Query: 654 F 656
+
Sbjct: 385 Y 385
Score = 54.0 bits (124), Expect = 4e-06
Identities = 23/32 (71%), Positives = 26/32 (81%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ETMHL++LP YTT G IH V NNQIGFTT P
Sbjct: 385 YETMHLTNLPNYTTGGVIHIVINNQIGFTTDP 416
Score = 41.9 bits (94), Expect = 0.016
Identities = 15/35 (42%), Positives = 25/35 (71%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQR 106
LR+IL RL Q YC ++G+E+ +I+ L +W+R +
Sbjct: 167 LRDILIRLNQVYCGHLGLEYTYIHDLVMLDWLRDK 201
>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza
sativa (Rice)
Length = 1016
Score = 211 bits (516), Expect = 1e-53
Identities = 105/186 (56%), Positives = 139/186 (74%), Gaps = 7/186 (3%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N + + D+++++L RL ST FE+FLA+KW++ KRFGLEG E LIP MK++ D + LG
Sbjct: 221 NAREYSYDRRQVMLDRLMWSTQFESFLAQKWTTAKRFGLEGAETLIPGMKEMFDRAADLG 280
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG--LEAED-----DGSGDVKYHLGTYI 458
VESI++GMPHRGRLNVL NV RKPL Q+F++F+G AE+ G+GDVKYHLGT
Sbjct: 281 VESIVIGMPHRGRLNVLGNVVRKPLRQIFSEFSGGTKPAEEGEGLYTGTGDVKYHLGTSY 340
Query: 459 ERLNRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFA 638
+R R K+I L++ ANPSHLEAVDPVV GKTRA+Q+Y D + K + +LLHGD +F+
Sbjct: 341 DRPTR-GGKHIHLSLVANPSHLEAVDPVVAGKTRAKQYYSNDLDRTKNLGVLLHGDGSFS 399
Query: 639 GQGVVF 656
GQGVV+
Sbjct: 400 GQGVVY 405
Score = 52.8 bits (121), Expect = 9e-06
Identities = 21/36 (58%), Positives = 26/36 (72%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LR +L RLEQAYC IG E+M I E+CNW+R R+
Sbjct: 182 LRSVLERLEQAYCGTIGYEYMHIPDREKCNWLRDRI 217
Score = 52.4 bits (120), Expect = 1e-05
Identities = 22/32 (68%), Positives = 25/32 (78%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+HLS LP YTT GTIH V NNQ+ FTT P
Sbjct: 405 YETLHLSALPNYTTGGTIHIVVNNQVAFTTDP 436
>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 1012
Score = 209 bits (510), Expect = 6e-53
Identities = 95/180 (52%), Positives = 130/180 (72%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P ++ AD ++ I + ++ FENFLAKK+ +EKRFGLEGCE I +M Q ++ S++
Sbjct: 244 PGAWELAADHRKWIWVNIMKAVTFENFLAKKYGTEKRFGLEGCESFIASMAQCLETSSEQ 303
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRV 476
GVE++ +GM HRGRLN L NVC KPLHQL TQF + E GSGDVKYHLGT ER+
Sbjct: 304 GVETVAIGMAHRGRLNTLVNVCSKPLHQLLTQFKPISLEGLGSGDVKYHLGTCAERVLER 363
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+ K + ++V ANPSHLE+VD V G+ RAEQ +GD +G+K ++IL+HGDAA++GQG+ +
Sbjct: 364 SGKKMHVSVTANPSHLESVDSVTVGRVRAEQVEKGDIKGQKSLAILVHGDAAYSGQGICY 423
Score = 56.8 bits (131), Expect = 5e-07
Identities = 24/33 (72%), Positives = 26/33 (78%)
Frame = +1
Query: 652 CFETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
C+ETMHL+ LP YTT G IH V NNQIGFTT P
Sbjct: 422 CYETMHLTKLPDYTTGGVIHSVINNQIGFTTDP 454
Score = 39.1 bits (87), Expect = 0.11
Identities = 13/35 (37%), Positives = 24/35 (68%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQR 106
LREI+ RL + YC ++G+E+++I+ W+R +
Sbjct: 206 LREIIKRLNKVYCGHLGLEYIYIHDSTVLEWLRYK 240
>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
CaKGD1 2-oxoglutarate dehydrogenase; n=4;
Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida
albicans CaKGD1 2-oxoglutarate dehydrogenase -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 997
Score = 206 bits (502), Expect = 6e-52
Identities = 102/181 (56%), Positives = 130/181 (71%), Gaps = 1/181 (0%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P K + D+KR IL R+ S FE+FLA K+ ++KRFGLEG E ++P MK +ID S +
Sbjct: 220 PEPYKYSPDEKRQILDRVIWSCSFESFLASKFPNDKRFGLEGAESVVPGMKAMIDTSVEF 279
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRV 476
GVE I++GMPHRGRLN+L+NV RKP +F++F G D+GSGDVKYHLG R
Sbjct: 280 GVEDIVIGMPHRGRLNMLSNVVRKPNESIFSEFTGSREFDEGSGDVKYHLGMNYAR-PTT 338
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGD-NEGKKVMSILLHGDAAFAGQGVV 653
+ K++ L++ ANPSHLE+ D VV GKTRA Q Y+ D E KK MSILLHGDAAF+GQGVV
Sbjct: 339 SGKHVNLSLVANPSHLESEDGVVLGKTRAIQQYKNDIGEYKKAMSILLHGDAAFSGQGVV 398
Query: 654 F 656
+
Sbjct: 399 Y 399
Score = 50.4 bits (115), Expect = 5e-05
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ETM L++LP Y+T GTIH + NNQIGFTT P
Sbjct: 399 YETMGLANLPDYSTGGTIHIIVNNQIGFTTDP 430
Score = 48.4 bits (110), Expect = 2e-04
Identities = 19/43 (44%), Positives = 30/43 (69%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNK 130
LREI++ E+ YC + G+E++ I S EQC+W+R+R+ E K
Sbjct: 182 LREIISNCERLYCQSYGVEYIHIPSKEQCDWLRERIEIPEPYK 224
>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1013
Score = 197 bits (481), Expect = 2e-49
Identities = 98/175 (56%), Positives = 127/175 (72%), Gaps = 4/175 (2%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
+K IL RL+ + FE FL K+ + +RFGL+GCE LIP MK +ID +T+ GVESI++GM
Sbjct: 240 EKIKILERLSWADQFEGFLGLKYRATRRFGLDGCESLIPGMKAMIDTATEDGVESIVLGM 299
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAG----LEAEDDGSGDVKYHLGTYIERLNRVTNKNI 491
PHRGRLNVLANV RKPL +F +F G +E E +GDVKYHLGT +R+ + K +
Sbjct: 300 PHRGRLNVLANVVRKPLPAIFNEFNGGVISIEGEYSATGDVKYHLGTSYDRVTS-SGKKV 358
Query: 492 RLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
L++ ANPSHLEAV+P+V GK RA+Q Y D E KK M++ LHGDA+ AGQGVV+
Sbjct: 359 HLSLVANPSHLEAVNPLVEGKVRAKQHYSKDTEQKKSMAVQLHGDASVAGQGVVY 413
Score = 52.0 bits (119), Expect = 2e-05
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+HLS+L Y+T GT+H V NNQIGFTT P
Sbjct: 413 YETLHLSNLDNYSTGGTVHIVVNNQIGFTTNP 444
Score = 50.8 bits (116), Expect = 4e-05
Identities = 22/65 (33%), Positives = 38/65 (58%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKDER*PEEAHPGSSNQIN 181
LR++L RL++ YC +IGIE+M I E C+WIR + E ++ P++ +++
Sbjct: 193 LRQVLKRLKETYCGDIGIEYMHIQDREMCDWIRDKF---ETSQPVEIPDKEKIKILERLS 249
Query: 182 WVREF 196
W +F
Sbjct: 250 WADQF 254
>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 1014
Score = 197 bits (480), Expect = 3e-49
Identities = 99/183 (54%), Positives = 129/183 (70%), Gaps = 3/183 (1%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + DQKR IL RLT +T FE+FL+ K+ ++KRFGLEG E ++P +K ++D S +L
Sbjct: 235 PEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVEL 294
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD--GSGDVKYHLGTYIERLN 470
GVE I++GM HRGRLNVL+NV RKP +F++F G A DD GSGDVKYHLG +R
Sbjct: 295 GVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQR-P 353
Query: 471 RVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGD-NEGKKVMSILLHGDAAFAGQG 647
+ K + L++ ANPSHLE+ DPVV G+TRA + D E K + +LLHGDAAFAGQG
Sbjct: 354 TTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQG 413
Query: 648 VVF 656
VV+
Sbjct: 414 VVY 416
Score = 47.2 bits (107), Expect = 4e-04
Identities = 20/32 (62%), Positives = 23/32 (71%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ETM LP Y+T GTIH + NNQIGFTT P
Sbjct: 416 YETMGFLTLPEYSTGGTIHVITNNQIGFTTDP 447
Score = 44.0 bits (99), Expect = 0.004
Identities = 15/40 (37%), Positives = 30/40 (75%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATE 121
L+EI++ LE+ YC++ G+++ I S ++C+W+R+R+ E
Sbjct: 197 LKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPE 236
>UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 component;
n=1; Gluconobacter oxydans|Rep: 2-Oxoglutarate
dehydrogenase E1 component - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 885
Score = 176 bits (428), Expect = 5e-43
Identities = 89/175 (50%), Positives = 121/175 (69%), Gaps = 3/175 (1%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
D KR++LA LTR+ GFE F K++ +RFGLEG E +I A++ +ID + + + S+ +G
Sbjct: 144 DPKRILLA-LTRAEGFEQFCQKRFMGMRRFGLEGGESVIVALRTLIDAAAQDDIRSVSLG 202
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD---GSGDVKYHLGTYIERLNRVTNKNI 491
MPHRGRLNV+AN+ RKP +F++FAG + D GSGDVKYHLGT + +
Sbjct: 203 MPHRGRLNVMANILRKPFAAIFSEFAGASFKPDTIEGSGDVKYHLGTATTLEH--AGHTV 260
Query: 492 RLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
R+++ NPSHLEAVDPVV G+ RA+Q D E + + IL+HGDAAFAGQGVV+
Sbjct: 261 RISLLPNPSHLEAVDPVVLGRVRADQDREKDRERQHHLGILVHGDAAFAGQGVVY 315
Score = 44.0 bits (99), Expect = 0.004
Identities = 18/30 (60%), Positives = 22/30 (73%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
+ET+ LS L Y T GT+H + NNQIGFTT
Sbjct: 315 YETLSLSKLEGYRTGGTVHVIINNQIGFTT 344
>UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: Oxoglutarate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 384
Score = 171 bits (415), Expect = 2e-41
Identities = 92/173 (53%), Positives = 115/173 (66%), Gaps = 3/173 (1%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
QKR IL+R+ ++ FE FL K+ +KRF LEG E LI A+ +I+ + +GVE ++GM
Sbjct: 174 QKRRILSRIHKAELFEKFLHTKYVGQKRFSLEGGETLIAALDAMIEHAPDVGVEEFVLGM 233
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAG--LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRL 497
HRGRL+VLAN RKP LF QF+ + G GDVKYHLG Y L T K I +
Sbjct: 234 AHRGRLSVLANTLRKPFDVLFEQFSENYIPHTVAGDGDVKYHLG-YEAALETTTGKTIEV 292
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYRGD-NEGKKVMSILLHGDAAFAGQGVV 653
+ ANPSHLE V+PVV GKTRA Q RGD E ++V +L+HGDAAFAGQGVV
Sbjct: 293 RLAANPSHLEIVNPVVEGKTRARQRIRGDATERRRVCPLLIHGDAAFAGQGVV 345
Score = 42.7 bits (96), Expect = 0.009
Identities = 18/31 (58%), Positives = 22/31 (70%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++ S L Y+T GT+H V N QIGFTT P
Sbjct: 347 ETLNFSQLTGYSTGGTLHFVINKQIGFTTLP 377
Score = 41.9 bits (94), Expect = 0.016
Identities = 15/42 (35%), Positives = 26/42 (61%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERN 127
LR+I+ ++ YC+N+G+E+M + W++ RM AT N
Sbjct: 126 LRDIVEAVKDTYCSNVGVEYMHVQDHAAREWLQVRMEATNNN 167
>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Geobacter sulfurreducens
Length = 894
Score = 170 bits (414), Expect = 3e-41
Identities = 87/179 (48%), Positives = 118/179 (65%), Gaps = 1/179 (0%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N ++ DQK IL +L ++ FE FL +K+ +KRF LEG E LIPA+ V++ + +LG
Sbjct: 158 NRPPVSLDQKLRILEKLREASLFEEFLHRKFLGQKRFSLEGGEALIPALDAVVERAARLG 217
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA-GLEAEDDGSGDVKYHLGTYIERLNRV 476
V+ +++GM HRGRLNVLA + KP+ +F +FA +E G GDVKYH G +R
Sbjct: 218 VDDLVLGMAHRGRLNVLATIIGKPVENIFAEFADNVELAFVGDGDVKYHKGFSSDR-RFA 276
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+I L + NPSHLEAV+PVV GK RA Q RG ++V+ +L+HGDAAFAGQGVV
Sbjct: 277 DGSSIHLTLAFNPSHLEAVNPVVEGKCRARQDARGPGGDRRVLPVLIHGDAAFAGQGVV 335
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/31 (64%), Positives = 23/31 (74%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS L Y T GT+H V NNQIGFTT P
Sbjct: 337 ETLNLSQLEGYRTGGTLHIVINNQIGFTTVP 367
Score = 40.3 bits (90), Expect = 0.049
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LREIL L + YC ++G+EFM I + W+ +RM
Sbjct: 118 LREILATLRETYCRSVGVEFMHIQDPAERTWLIERM 153
>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Corynebacterium glutamicum (Brevibacterium
flavum)
Length = 1257
Score = 170 bits (414), Expect = 3e-41
Identities = 84/173 (48%), Positives = 116/173 (67%), Gaps = 3/173 (1%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
+++ IL +L + FENFL K+ +KRF LEG E LIP M ID + G++ +++GM
Sbjct: 518 EQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGM 577
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAGL--EAEDDGSGDVKYHLGTYIERLNRVTNKNIRL 497
PHRGRLNVL N+ KPL +F +F G + + GSGDVKYHLG+ + L + I++
Sbjct: 578 PHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKV 637
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYRGDN-EGKKVMSILLHGDAAFAGQGVV 653
++ ANPSHLEAV+PV+ G RA+Q Y +GK V+ +LLHGDAAFAG G+V
Sbjct: 638 SLTANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIV 690
Score = 43.2 bits (97), Expect = 0.007
Identities = 19/31 (61%), Positives = 22/31 (70%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++L+ L Y GTIH V NNQIGFTT P
Sbjct: 692 ETINLAKLRGYDVGGTIHIVVNNQIGFTTTP 722
Score = 33.5 bits (73), Expect = 5.7
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVA 115
LRE+L+RL AY +G E+ I ++ W++ R+ A
Sbjct: 472 LREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEA 509
>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
decarboxylase - Lentisphaera araneosa HTCC2155
Length = 913
Score = 169 bits (411), Expect = 6e-41
Identities = 85/181 (46%), Positives = 116/181 (64%), Gaps = 2/181 (1%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N N QK IL +LT+ GFE FL K+ +KRF LEG E IPAM ++ + ++LG
Sbjct: 161 NKPNFNKTQKMNILKKLTQGVGFEKFLGVKYVGQKRFSLEGLEAFIPAMTELFNQGSRLG 220
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD--GSGDVKYHLGTYIERLNR 473
V+ +MGM HRGRLNVLAN+ K LF +F G DD G GDVKYH+G + +
Sbjct: 221 VQEFVMGMAHRGRLNVLANLFEKEYKALFQEFEGHALPDDVGGDGDVKYHMGHSADVVTE 280
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
N + L++ ANPSHLEAV+PVV G+ RA+ +N+ K++ IL+HGDAA +GQG++
Sbjct: 281 DGNP-LHLSLAANPSHLEAVNPVVLGRVRAKIEELYENDPNKIVPILVHGDAAISGQGII 339
Query: 654 F 656
+
Sbjct: 340 Y 340
Score = 39.9 bits (89), Expect = 0.065
Identities = 13/36 (36%), Positives = 25/36 (69%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
L++I++ LE YC++IG+E+ + S E W+ ++M
Sbjct: 121 LKDIISHLEDTYCSSIGVEYRYSQSSEMRQWLHEKM 156
Score = 37.5 bits (83), Expect = 0.35
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFT 741
+E ++++L Y T GT+H V NNQ+GFT
Sbjct: 340 YEICNMANLDGYGTGGTVHVVLNNQVGFT 368
>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative; n=9; Plasmodium|Rep:
2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative - Plasmodium vivax
Length = 1059
Score = 168 bits (408), Expect = 1e-40
Identities = 79/174 (45%), Positives = 113/174 (64%), Gaps = 4/174 (2%)
Frame = +3
Query: 147 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 326
KR IL R+ FEN++A K+++ KRFG++GCE LI MK +I + + ES++M M
Sbjct: 251 KRKILENTARAFIFENYMAAKFATTKRFGVDGCETLITGMKALISRAAMVHTESVLMSMS 310
Query: 327 HRGRLNVLANVCRKPLHQLFTQFAGLEAEDDG----SGDVKYHLGTYIERLNRVTNKNIR 494
HRGRLNVL NV KPL + +F G D +GDVKYHLG I+ + +N+ I
Sbjct: 311 HRGRLNVLFNVLHKPLENMMCEFRGKTGFTDNIWGNTGDVKYHLGVEIDHFDEESNRYIH 370
Query: 495 LAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+ + N SHLE+VDP++ G+ RA+Q+Y D E +KV+ I +HGDA+ AGQG+ +
Sbjct: 371 MGIVDNSSHLESVDPILMGQARAQQYYCNDKEKEKVLPITIHGDASIAGQGIAY 424
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/32 (62%), Positives = 24/32 (75%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+ +S LP+Y GTIH V NNQIGFTT P
Sbjct: 424 YETLQMSKLPSYNVGGTIHIVVNNQIGFTTYP 455
Score = 38.3 bits (85), Expect = 0.20
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LR +++RLEQ YC IG E+M I N+I +R+
Sbjct: 203 LRSLIDRLEQTYCGTIGFEYMHITDESVVNYIVKRI 238
>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Cystobacterineae|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Myxococcus xanthus (strain
DK 1622)
Length = 963
Score = 167 bits (405), Expect = 3e-40
Identities = 86/180 (47%), Positives = 116/180 (64%), Gaps = 2/180 (1%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N T + D+ R IL +L+ + GFE+FL K+ KRF L+G E LIP + + +V+T +G
Sbjct: 205 NRTDFSPDECRHILTKLSYAEGFEHFLHTKYVGAKRFSLDGGEALIPMLDALGEVATGMG 264
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD--GSGDVKYHLGTYIERLNR 473
+ I++GM HRGRLNVL N+ K Q+F++F G D G GDVKYH+G + R
Sbjct: 265 LREIVIGMAHRGRLNVLTNILGKQPDQIFSEFDGPRNPQDYLGRGDVKYHMGFSSDHTTR 324
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ + L++ NPSHLEAVDPVV G+ RA+Q GD E VM +L+HGDAAF GQGVV
Sbjct: 325 -QGRKLHLSLAFNPSHLEAVDPVVEGRVRAKQDRGGDTERTSVMPLLIHGDAAFIGQGVV 383
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/31 (64%), Positives = 24/31 (77%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS L YTT GT+H V NNQ+GFTT P
Sbjct: 385 ETLNLSGLKGYTTGGTVHVVINNQVGFTTDP 415
Score = 37.9 bits (84), Expect = 0.26
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKD 133
L E+L RL + Y + IG+E+M + E+ W+ RM + E D
Sbjct: 165 LTELLARLRRTYTDTIGVEYMHMLDSERRRWLMHRMESNENRTD 208
>UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E1
component, sucA; n=1; Candidatus Protochlamydia
amoebophila UWE25|Rep: Probable 2-oxoglutarate
dehydrogenase E1 component, sucA - Protochlamydia
amoebophila (strain UWE25)
Length = 890
Score = 166 bits (403), Expect = 6e-40
Identities = 83/178 (46%), Positives = 119/178 (66%), Gaps = 3/178 (1%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 311
+ +QK+ +LA L+RS FE FL K+ +KRF LEG E LIP + +I+ + GV+
Sbjct: 151 LTKEQKQHVLACLSRSELFETFLHTKYIGQKRFSLEGAETLIPMLDLLIEAGAEQGVQEF 210
Query: 312 IMGMPHRGRLNVLANVCRKPLHQLFTQFAG--LEAEDDGSGDVKYHLGTYIERLNRVTNK 485
++GM HRGRLNVLAN+ K L +F++F + +G GDVKYH G E++ K
Sbjct: 211 LVGMAHRGRLNVLANILNKSLDTIFSEFGEEYIPTSLEGMGDVKYHKGYTGEKIKTRLGK 270
Query: 486 NIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEG-KKVMSILLHGDAAFAGQGVVF 656
+I++++ NPSHLE+V+ VV GKTRA+QF G + KK++ IL+HGDAA +GQGVV+
Sbjct: 271 SIKISLSPNPSHLESVNAVVEGKTRAKQFLAGGEKARKKIIPILIHGDAAVSGQGVVY 328
Score = 47.2 bits (107), Expect = 4e-04
Identities = 21/32 (65%), Positives = 23/32 (71%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+ LS L Y T GTIH V NNQIGFTT P
Sbjct: 328 YETLQLSQLKGYETGGTIHFVINNQIGFTTIP 359
>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family
protein - Tetrahymena thermophila SB210
Length = 992
Score = 164 bits (398), Expect = 2e-39
Identities = 82/180 (45%), Positives = 120/180 (66%), Gaps = 6/180 (3%)
Frame = +3
Query: 135 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
N D+K+ L RL R+ F FL ++S+ KRFG+EGC+ I + ++D + + GV+S+I
Sbjct: 214 NVDRKKT-LERLLRNEQFNLFLKNRFSTSKRFGIEGCDSFISGLGALVDHACENGVQSLI 272
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGL------EAEDDGSGDVKYHLGTYIERLNRV 476
+GMPHRGRLN LA V K Q+F +F + +AE SGDVKYHLG E++N
Sbjct: 273 LGMPHRGRLNTLACVFNKNPEQIFAEFQEIRDKSLDDAEWGNSGDVKYHLGCTTEKVN-P 331
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+ K I++++ NPSHLE V+PV G RA Q ++GD+ G K + +L+HGD++F+GQGVV+
Sbjct: 332 SGKKIKMSILPNPSHLETVNPVTMGCVRAVQDFKGDSTGLKTLGVLVHGDSSFSGQGVVY 391
Score = 40.7 bits (91), Expect = 0.037
Identities = 14/32 (43%), Positives = 22/32 (68%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+E++ + +L Y+ G +H + NNQIGFTT P
Sbjct: 391 YESLQMQELVGYSPRGIVHIIVNNQIGFTTTP 422
>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component; n=4;
Bacteroidetes|Rep: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 946
Score = 162 bits (394), Expect = 7e-39
Identities = 84/177 (47%), Positives = 113/177 (63%), Gaps = 2/177 (1%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 311
+ D+K+ IL++L + FENFL K+ +KRF LEG E IPA+ ++I S +LGVE +
Sbjct: 197 LTLDEKKRILSKLNEAVVFENFLHTKYVGQKRFSLEGGETTIPALDKMITASAELGVEEV 256
Query: 312 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAED--DGSGDVKYHLGTYIERLNRVTNK 485
++GM HRGRLNVLAN+ K Q+F +F G D G GDVKYH+G Y + +
Sbjct: 257 VIGMAHRGRLNVLANIMGKTYEQIFNEFEGNIKPDMTMGDGDVKYHMG-YSSEVVTPKGQ 315
Query: 486 NIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
I L + NPSHLEAVDPVV G RA+ + KKV+ +L+HGDAA A QG+V+
Sbjct: 316 KINLKLMPNPSHLEAVDPVVLGFVRAKGDRLYGYDYKKVLPVLIHGDAAVAAQGIVY 372
Score = 41.1 bits (92), Expect = 0.028
Identities = 17/30 (56%), Positives = 21/30 (70%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
+E + +S L Y T GTIH V NNQ+GFTT
Sbjct: 372 YEIVQMSKLAGYQTGGTIHFVINNQVGFTT 401
>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
dehydrogenase E1 - Blastopirellula marina DSM 3645
Length = 929
Score = 161 bits (392), Expect = 1e-38
Identities = 80/177 (45%), Positives = 113/177 (63%), Gaps = 1/177 (0%)
Frame = +3
Query: 126 TKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVE 305
+ + D +R IL RLT + FE F+ KK+ K F LEG E LIP + I + G+
Sbjct: 185 SSLGRDTQRRILQRLTEAMVFEEFVRKKYLGAKTFSLEGSETLIPLLDLAIHGFAEQGIS 244
Query: 306 SIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD-GSGDVKYHLGTYIERLNRVTN 482
+++ MPHRGRL+VLANV R+P ++F+QF + + G GDVKYH+G + + +
Sbjct: 245 ELVLAMPHRGRLSVLANVIRQPPREIFSQFEDADPKRHIGGGDVKYHMGASGDYV-AASG 303
Query: 483 KNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
K + +++C NPSHLE VDPV G+ RA+Q RGD E + +L+HGDAAFAG+GVV
Sbjct: 304 KKVHVSLCFNPSHLEYVDPVALGRMRAKQDRRGDTERQMGAVVLIHGDAAFAGEGVV 360
Score = 46.0 bits (104), Expect = 0.001
Identities = 18/31 (58%), Positives = 24/31 (77%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS L Y T GT+H + NNQ+GFTT+P
Sbjct: 362 ETLNLSQLHGYRTGGTLHVIVNNQLGFTTQP 392
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 158 bits (384), Expect = 1e-37
Identities = 88/192 (45%), Positives = 119/192 (61%), Gaps = 12/192 (6%)
Frame = +3
Query: 114 PPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTK 293
P + K+ IL++L + GFE F+ K+ KRFGL+G E LIPA++Q++ +
Sbjct: 233 PDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQ 292
Query: 294 LGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDD--GSGDVKYHLGTYIER 464
+G++ +++GM HRGRLNVL+ V KP +F +F G DD GSGDVKYHLG +R
Sbjct: 293 MGLKEVVLGMAHRGRLNVLSQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDR 352
Query: 465 LNRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFY-----RGD----NEGKKVMSILL 617
+ L++ ANPSHLE V+PVV GK RA+Q R D +E KV+ +LL
Sbjct: 353 --EFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLL 410
Query: 618 HGDAAFAGQGVV 653
HGDAAFAGQGVV
Sbjct: 411 HGDAAFAGQGVV 422
Score = 38.3 bits (85), Expect = 0.20
Identities = 16/31 (51%), Positives = 20/31 (64%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
E + LS L + GT+H + NNQIGFTT P
Sbjct: 424 ECLGLSGLKGHRVAGTLHFIINNQIGFTTNP 454
Score = 35.9 bits (79), Expect = 1.1
Identities = 14/39 (35%), Positives = 26/39 (66%)
Frame = +2
Query: 8 EILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATER 124
E+L+ L++ YC IG+EFM I+ + WI++R+ ++
Sbjct: 197 EMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDK 235
>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_5,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1002
Score = 157 bits (382), Expect = 2e-37
Identities = 81/177 (45%), Positives = 109/177 (61%), Gaps = 5/177 (2%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
+QK RL + F FL KK+++ KRFG+EGC+ +I ++ ++D + GVE I+ G
Sbjct: 229 EQKLKTFERLGQEHAFSTFLQKKFNTSKRFGIEGCDSMISGLQSMVDSAASAGVEYIVFG 288
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQF---AGLEAED--DGSGDVKYHLGTYIERLNRVTNK 485
M HRGRLN L NV +K ++ +F G+ ED SGDVKYHLG+ + + + K
Sbjct: 289 MAHRGRLNTLYNVFQKSPEEIMVEFQDLKGIYNEDIWGNSGDVKYHLGS-VHNV-KFGEK 346
Query: 486 NIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+RL + NPSHLE VDP V GK RA Q Y D G K +L+HGDAA AGQG+VF
Sbjct: 347 KLRLEMLPNPSHLETVDPCVYGKVRAIQDYHKDRNGDKAFGVLIHGDAAVAGQGIVF 403
Score = 46.4 bits (105), Expect = 8e-04
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LR+++N LE+AYC I E+M I S E+ NWIR+++
Sbjct: 183 LRDLINYLEKAYCGKISYEYMHIQSTEERNWIREQI 218
Score = 44.0 bits (99), Expect = 0.004
Identities = 18/32 (56%), Positives = 24/32 (75%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
FE++ ++DL Y + G IH V+NNQIGFTT P
Sbjct: 403 FESLQMADLEGYKSGGIIHVVSNNQIGFTTVP 434
>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
component - Rickettsia felis (Rickettsia azadi)
Length = 977
Score = 155 bits (377), Expect = 8e-37
Identities = 85/176 (48%), Positives = 110/176 (62%), Gaps = 3/176 (1%)
Frame = +3
Query: 135 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
+++ K+ IL L GFE +L K+ KRF +EG + I AM + ID+S GVE I+
Sbjct: 237 SSEDKKTILNDLVEVEGFEQYLHTKFPGAKRFSVEGGDASIVAMSKAIDLSMNQGVEEIV 296
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDD--GSGDVKYHLGTYIERLNRVTNK 485
+GM HRGRLN L V KP + F +G D+ SGDVKYHLG +R + NK
Sbjct: 297 IGMAHRGRLNTLTKVVGKPYKAVIAGFISGSVFPDELNVSGDVKYHLGYSSDRT--IDNK 354
Query: 486 NIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
I L++ NPSHLEAV+P+V GK RA+Q GD + KV +IL+HGDAAF GQGVV
Sbjct: 355 KIHLSLADNPSHLEAVNPIVAGKVRAKQDILGDTKRSKVKAILVHGDAAFCGQGVV 410
Score = 35.1 bits (77), Expect = 1.9
Identities = 12/36 (33%), Positives = 25/36 (69%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
L E++ +L++ Y +IG+EF I ++E+ NW+ ++
Sbjct: 195 LSELVTKLDKTYTGSIGVEFEQIENVEEKNWLYNKL 230
Score = 34.3 bits (75), Expect = 3.3
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFT 741
E++ +S L AY G +H V NNQ+GFT
Sbjct: 412 ESLSMSPLAAYDIGGILHFVINNQLGFT 439
>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=16; cellular organisms|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Robiginitalea biformata
HTCC2501
Length = 940
Score = 155 bits (376), Expect = 1e-36
Identities = 79/181 (43%), Positives = 114/181 (62%), Gaps = 2/181 (1%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N + ++K+ IL +L + FE FL K+ +KRF LEG E LIPA+ +++ + +LG
Sbjct: 179 NHPNFSPERKKYILRKLNEAVSFEGFLHTKYVGQKRFSLEGNESLIPAVDAIVERAAELG 238
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD-GSGDVKYHLG-TYIERLNR 473
V+ +MGM HRGRLNVL N+ KP +F++F G + E + GDVKYHLG T + + N
Sbjct: 239 VQQFVMGMAHRGRLNVLTNIFGKPATDIFSEFEGKDYEQEIFDGDVKYHLGWTSMRKTN- 297
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ +I + + NPSHLE V VV G TRA+Q + KV+ I++HGDAA AGQG+
Sbjct: 298 -SGDSINMNIAPNPSHLETVGAVVEGITRAKQDRHFPEDFSKVLPIVVHGDAAIAGQGIA 356
Query: 654 F 656
+
Sbjct: 357 Y 357
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/34 (50%), Positives = 26/34 (76%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQ 103
LREI++ L + YC+ IG+E+M+I S E+ WI+Q
Sbjct: 139 LREIIDHLTRIYCDAIGVEYMYIRSPERVEWIQQ 172
Score = 40.7 bits (91), Expect = 0.037
Identities = 17/30 (56%), Positives = 21/30 (70%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
+E + ++ L Y T GTIH V NNQIGFTT
Sbjct: 357 YEVVQMAGLDGYGTAGTIHIVVNNQIGFTT 386
>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
component - Leptospira interrogans
Length = 920
Score = 153 bits (370), Expect = 6e-36
Identities = 78/170 (45%), Positives = 107/170 (62%), Gaps = 1/170 (0%)
Frame = +3
Query: 147 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 326
K + +L ++ FE FLAKK+ +KRF LEG E IP + +++ + ++ +++GM
Sbjct: 184 KLRLFEKLFQADYFETFLAKKYVGKKRFSLEGGESFIPLLDTIVEEAGYHQMDGLVIGMA 243
Query: 327 HRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGS-GDVKYHLGTYIERLNRVTNKNIRLAV 503
HRGRLNVL N+ KP +F +F +D+ S DVKYHLG R+ + K ++L++
Sbjct: 244 HRGRLNVLVNIIEKPASLIFAEFEEKTDKDNLSYADVKYHLGYSNSRMT-TSGKEVKLSL 302
Query: 504 CANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
NPSHLE VDPVV G RA Q GD + K M IL+HGDAAFAGQGVV
Sbjct: 303 AFNPSHLECVDPVVTGSVRARQTLIGDKDRSKYMPILIHGDAAFAGQGVV 352
Score = 46.4 bits (105), Expect = 8e-04
Identities = 20/31 (64%), Positives = 23/31 (74%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++L +L YTT GT H V NNQIGFTT P
Sbjct: 354 ETLNLMNLEGYTTGGTFHIVVNNQIGFTTLP 384
Score = 36.3 bits (80), Expect = 0.81
Identities = 14/40 (35%), Positives = 26/40 (65%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATE 121
L EI++ E+ YCN IG E ++ + E+ W++++M + E
Sbjct: 135 LAEIVDLYEKVYCNTIGAEHFYLVNDEEREWLQKKMESPE 174
>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
fastidiosa
Length = 967
Score = 152 bits (369), Expect = 8e-36
Identities = 84/177 (47%), Positives = 108/177 (61%), Gaps = 4/177 (2%)
Frame = +3
Query: 135 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
NA ++ IL RLT + G E +L K+ +KRF LEG + LIP M ++ + V+ I+
Sbjct: 218 NATNRKRILERLTAAEGLERYLHTKYVGQKRFSLEGSDTLIPLMDTLVRQAGNNDVKDIV 277
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGL--EAEDD--GSGDVKYHLGTYIERLNRVTN 482
+GM HRGRLNVL N K +LF +F G A D +GDVKYH+G + +
Sbjct: 278 VGMAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHHDRAHTGDVKYHMG-FSADIAVGDG 336
Query: 483 KNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
K + LA+ NPSHLE VDPVV G R+ Q GD E K V+ IL+HGDAAFAGQGVV
Sbjct: 337 KQVHLALAFNPSHLEIVDPVVAGSVRSRQERFGDTERKTVLPILIHGDAAFAGQGVV 393
Score = 36.7 bits (81), Expect = 0.61
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LR +L L+ Y + IG EFM I+ EQ WI +R+
Sbjct: 173 LRNLLAHLKATYTDTIGTEFMHISEFEQRQWIYRRL 208
Score = 34.3 bits (75), Expect = 3.3
Identities = 13/29 (44%), Positives = 18/29 (62%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
E + +S + GT+H + NNQIGFTT
Sbjct: 395 ELLQMSQARGFAVGGTLHVIINNQIGFTT 423
>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Azotobacter vinelandii
Length = 943
Score = 151 bits (367), Expect = 1e-35
Identities = 78/171 (45%), Positives = 103/171 (60%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
+ K +L RL+ + G E +L K+ KRFGLEG E L+P + ++I S G + +++G
Sbjct: 204 EAKSHLLERLSAAEGLEKYLGTKYPGTKRFGLEGGESLVPVVDEIIQRSGSYGTKEVVIG 263
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLA 500
M HRGRLN+L N K LF +F G + GSGDVKYH G + + + LA
Sbjct: 264 MAHRGRLNLLVNALGKNPRDLFDEFEGKHLVELGSGDVKYHQGFSSNVM--TSGGEVHLA 321
Query: 501 VCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ NPSHLE V PVV G RA Q R D G+KV+ I +HGD+AFAGQGVV
Sbjct: 322 MAFNPSHLEIVSPVVEGSVRARQDRRVDATGEKVVPISIHGDSAFAGQGVV 372
Score = 43.2 bits (97), Expect = 0.007
Identities = 19/36 (52%), Positives = 22/36 (61%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LREIL L++ YC IG EF I EQ NW QR+
Sbjct: 157 LREILQALQETYCRTIGAEFTHIVDSEQRNWFAQRL 192
Score = 41.5 bits (93), Expect = 0.021
Identities = 17/29 (58%), Positives = 20/29 (68%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET +S + Y T GTIH V NNQ+GFTT
Sbjct: 374 ETFQMSQIRGYKTGGTIHIVVNNQVGFTT 402
>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Francisella tularensis|Rep: 2-oxoglutarate
dehydrogenase E1 component - Francisella tularensis
subsp. tularensis (strain FSC 198)
Length = 941
Score = 150 bits (364), Expect = 3e-35
Identities = 78/173 (45%), Positives = 109/173 (63%), Gaps = 1/173 (0%)
Frame = +3
Query: 138 ADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVS-TKLGVESII 314
+D K+ IL +L + G E +LA ++ +KRFGLEG E LIP+++ +++ + ++ I
Sbjct: 200 SDSKKWILQQLVAAEGLEKYLALRYVGQKRFGLEGGESLIPSLQHIVEKAVSRHSTRFIQ 259
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIR 494
+GM HRGRLNVL NV K LF +F G ++E SGDVKYH+G + K +
Sbjct: 260 LGMAHRGRLNVLVNVMGKNPKDLFEEFEGKQSEKSLSGDVKYHMG--YSNYRSIDGKEAK 317
Query: 495 LAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+A+ NPSHLEAVDPVV G +A Q + KV+ IL+HGD+AF GQGVV
Sbjct: 318 IALAFNPSHLEAVDPVVEGAAKAIQDKLDGDVYSKVLPILIHGDSAFCGQGVV 370
Score = 38.7 bits (86), Expect = 0.15
Identities = 18/29 (62%), Positives = 19/29 (65%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET S AY T GTIH V NNQ+GFTT
Sbjct: 372 ETFGFSLTEAYGTGGTIHLVVNNQVGFTT 400
Score = 33.1 bits (72), Expect = 7.5
Identities = 12/39 (30%), Positives = 26/39 (66%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVAT 118
L++++N+ + Y +NIG E+ +I + E+ W++ R+ T
Sbjct: 157 LQQVINKAKAIYESNIGYEYRYIGNKEEKLWLQDRIEDT 195
>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=15; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Deinococcus radiodurans
Length = 956
Score = 150 bits (363), Expect = 4e-35
Identities = 80/178 (44%), Positives = 110/178 (61%), Gaps = 4/178 (2%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVID-VSTKLGVES 308
++ D++R ++ +L + G E +L ++ KRFGLEG E IP M ++I + GV+
Sbjct: 188 LSQDERRRLMQKLNAAEGLELYLKNRYPGVKRFGLEGGESFIPLMDRIIQQAGGRYGVKE 247
Query: 309 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAG---LEAEDDGSGDVKYHLGTYIERLNRVT 479
+++GM HRGRLN L N+ KP LF +F G L + D +GDVKYH+G Y + R
Sbjct: 248 VVVGMAHRGRLNTLVNIFGKPSGTLFDEFDGKKKLSDDPDIAGDVKYHMG-YSSDV-RTP 305
Query: 480 NKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ LA+ NPSHLE V PVV G RA Q RGD E K+V+ I +HGDAA +GQGVV
Sbjct: 306 GGPMHLAMAFNPSHLEIVSPVVHGSVRARQDRRGDTERKQVLPITVHGDAAVSGQGVV 363
Score = 35.5 bits (78), Expect = 1.4
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFT 741
ET++ S L +TT G I V NNQIGFT
Sbjct: 365 ETLNFSRLRGFTTGGAIRIVINNQIGFT 392
>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
component family protein; n=1; Tetrahymena thermophila
SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
family protein - Tetrahymena thermophila SB210
Length = 1054
Score = 149 bits (362), Expect = 5e-35
Identities = 79/170 (46%), Positives = 107/170 (62%), Gaps = 6/170 (3%)
Frame = +3
Query: 165 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 344
RL R F FL K+S+ KRFG EGC+ I + ++D + +E+I++GMPHRGRLN
Sbjct: 283 RLCRDYCFTEFLNNKFSTSKRFGSEGCDSFISGLGALVDHAADKKIENIVIGMPHRGRLN 342
Query: 345 VLANVCRKPLHQLFTQF-----AGLEAEDDG-SGDVKYHLGTYIERLNRVTNKNIRLAVC 506
L +V +KP + +F A + E+ G SGDVKYHLGT ++ + +RL++
Sbjct: 343 TLYSVLKKPAVNILAEFQDINVAKFDEENWGNSGDVKYHLGTTKDK--AYGDHTVRLSIM 400
Query: 507 ANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
ANPSHLEAV+PVV GK R Q D G K IL+HGDAAF+GQG+V+
Sbjct: 401 ANPSHLEAVNPVVYGKLRCVQDATQDTNGDKSFGILIHGDAAFSGQGIVY 450
Score = 47.2 bits (107), Expect = 4e-04
Identities = 18/43 (41%), Positives = 31/43 (72%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNK 130
LR++++ L+Q YCN +G ++M IN+ + +WIRQR+ E+ K
Sbjct: 229 LRDLIDHLKQIYCNKVGYQYMHINNKTERDWIRQRIENAEQFK 271
Score = 40.7 bits (91), Expect = 0.037
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+E++ + DL Y G IH V NNQIGFTT P
Sbjct: 450 YESIQMHDLKDYNNGGIIHIVVNNQIGFTTYP 481
>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Haemophilus influenzae
Length = 935
Score = 149 bits (362), Expect = 5e-35
Identities = 77/172 (44%), Positives = 105/172 (61%)
Frame = +3
Query: 138 ADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIM 317
++++ L LT + G E +L K+ KRF LEG + IP MK++I S++ GV ++M
Sbjct: 201 SEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDAFIPLMKEIIRHSSRQGVNDVVM 260
Query: 318 GMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRL 497
GM HRGRLN+L NV K LF +FAG + + +GDVKYH G + V +K + L
Sbjct: 261 GMAHRGRLNMLVNVLGKKPENLFDEFAG-KHSSERTGDVKYHQGFSSD--FAVDDKRVHL 317
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ NPSHLE V PVV G R+ Q D E KV++I +HGD+A AGQGVV
Sbjct: 318 TLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAITVHGDSAVAGQGVV 369
Score = 39.9 bits (89), Expect = 0.065
Identities = 14/36 (38%), Positives = 24/36 (66%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
L E+ L++ YC +IG+EFM + +EQ W++ +M
Sbjct: 155 LGELAQMLKETYCGSIGLEFMHVQDMEQKMWLQSKM 190
Score = 37.5 bits (83), Expect = 0.35
Identities = 16/29 (55%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+++S+ Y+ GTI V NNQIGFTT
Sbjct: 371 ETLNMSNTRGYSVGGTIRIVINNQIGFTT 399
>UniRef50_UPI0000DAE34D Cluster: hypothetical protein
Rgryl_01000074; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000074 - Rickettsiella
grylli
Length = 929
Score = 149 bits (360), Expect = 1e-34
Identities = 77/176 (43%), Positives = 113/176 (64%)
Frame = +3
Query: 135 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
+A K+ IL L R+ G E FL K+ ++KRF LEG + LIP ++ +I +++ VE I+
Sbjct: 194 SAKVKKNILKGLIRADGLEKFLGNKFVAQKRFSLEGGDSLIPLLEALITDASRAEVEEIV 253
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIR 494
+GM HRGRLNVL N+ K QLF +F G +++ SGDVKYH G + + + +
Sbjct: 254 IGMAHRGRLNVLINILGKSPAQLFEEFEGKMIQENRSGDVKYHKGFAADL--KTDHGVMH 311
Query: 495 LAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVFRD 662
+A+ NPSHLE V+PVV G R+ Q R + ++V+ +L+HGDAAF+GQGVV +
Sbjct: 312 VAMAFNPSHLEIVNPVVEGSVRSRQERRQEGGQQQVLPLLIHGDAAFSGQGVVMEN 367
Score = 41.1 bits (92), Expect = 0.028
Identities = 18/31 (58%), Positives = 20/31 (64%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
E LS AY T GT+H V NNQ+GFTT P
Sbjct: 366 ENFELSQTQAYGTGGTLHIVLNNQLGFTTDP 396
Score = 33.5 bits (73), Expect = 5.7
Identities = 13/44 (29%), Positives = 24/44 (54%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKD 133
+ +LN L++ YC +IG E+ I Q W+++R+ + D
Sbjct: 149 VESVLNHLKKIYCRSIGFEYEHIACHAQRTWLQERIESVTGKPD 192
>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 1304
Score = 149 bits (360), Expect = 1e-34
Identities = 82/174 (47%), Positives = 109/174 (62%), Gaps = 3/174 (1%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
D +R IL L R+ FE FL K+ +KRF LEG E LIP + ++ S + G+ + +G
Sbjct: 544 DAQRHILGTLIRAEAFEEFLQTKFMGQKRFSLEGGESLIPLLDHILADSARTGIHEVAIG 603
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAG--LEAEDDGSGDVKYHLGTY-IERLNRVTNKNI 491
M HRGRLNVLAN+ K Q+F +F G + GSGDVKYHLGT+ + L+ +
Sbjct: 604 MAHRGRLNVLANIAGKSYAQIFDEFEGNYMPNSVQGSGDVKYHLGTWGVYSLDDGLATKV 663
Query: 492 RLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+A ANPSHLEA D V+ G RA+Q + GD + ++ IL+HGDAAF GQGVV
Sbjct: 664 YMA--ANPSHLEAADGVLEGIVRAKQEHLGDPD-LPIIPILIHGDAAFIGQGVV 714
Score = 46.8 bits (106), Expect = 6e-04
Identities = 20/31 (64%), Positives = 23/31 (74%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS L Y T GTIH + NNQIGFTT P
Sbjct: 716 ETLNLSQLEGYKTGGTIHIIVNNQIGFTTGP 746
Score = 39.1 bits (87), Expect = 0.11
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LR+IL RL Y +GIE+M I EQ W+++R+
Sbjct: 499 LRDILTRLHDTYTRTVGIEYMHIQDPEQRAWVQKRI 534
>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
component; n=7; Bacteria|Rep: 2-oxoglutarate
dehydrogenase complex, E1 component - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 942
Score = 148 bits (358), Expect = 2e-34
Identities = 77/174 (44%), Positives = 104/174 (59%)
Frame = +3
Query: 129 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVES 308
+ +A+ K+ IL R T + E FL K+ +KRF LEG E I AM +++ V LG +
Sbjct: 193 RFSAEMKKRILERTTAAETLEKFLHTKYVGQKRFSLEGGESTIVAMDEIVRVGGSLGAQE 252
Query: 309 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKN 488
I++GM HRGRLNVL N K LF +F G A D +GDVKYHLG + ++
Sbjct: 253 IVIGMAHRGRLNVLVNTLGKSPSMLFAEFEGKAAADLTAGDVKYHLGFSSDVMS--PGGP 310
Query: 489 IRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGV 650
+ L + NPSHLE ++PVV G A Q R D +V+++L+HGDAA AGQGV
Sbjct: 311 VHLTLSFNPSHLEIINPVVEGSVYARQLRRKDEAKSQVIAVLIHGDAAVAGQGV 364
Score = 41.9 bits (94), Expect = 0.016
Identities = 18/36 (50%), Positives = 23/36 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LREIL L Q YC +IG E+M I+ Q WI+ R+
Sbjct: 150 LREILEALRQTYCGSIGSEYMHISDTGQKRWIQSRL 185
Score = 37.9 bits (84), Expect = 0.26
Identities = 16/29 (55%), Positives = 19/29 (65%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
E ++ S Y T GT+H V NNQIGFTT
Sbjct: 367 EMLNFSQTRGYGTGGTVHIVVNNQIGFTT 395
>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=12; root|Rep: 2-oxoglutarate dehydrogenase,
E1 component - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 963
Score = 148 bits (358), Expect = 2e-34
Identities = 84/179 (46%), Positives = 107/179 (59%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
PN+TK ++K IL RLT + G E FL K+ +KRF LEG E I +M ++I
Sbjct: 208 PNLTK---EKKLHILDRLTAAEGLERFLHTKYVGQKRFSLEGGESFIASMDELIQQGGIK 264
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRV 476
GV+ I++GM HRGRLNVL N K LF +F ED SGDVKYH G +
Sbjct: 265 GVQEIVIGMAHRGRLNVLVNSLGKVPADLFAEFDHTAPEDLPSGDVKYHQGFSSD--VTT 322
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ L++ NPSHLE V+PVV G RA R D +G +V+ +L+HGDAAFAGQGVV
Sbjct: 323 PGGPVHLSLAFNPSHLEIVNPVVEGSVRARMDRRADPKGLQVLPVLVHGDAAFAGQGVV 381
Score = 39.9 bits (89), Expect = 0.065
Identities = 17/29 (58%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+ L++ Y T GT+H V NNQIGFTT
Sbjct: 383 ETLALAETRGYFTGGTVHIVINNQIGFTT 411
Score = 39.1 bits (87), Expect = 0.11
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LRE++N L + YC IG E+M+ Q W +Q++
Sbjct: 166 LRELINALRETYCGTIGAEYMYATDQNQKRWWQQKL 201
>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
subunit - Solibacter usitatus (strain Ellin6076)
Length = 1220
Score = 146 bits (355), Expect = 4e-34
Identities = 75/159 (47%), Positives = 105/159 (66%), Gaps = 3/159 (1%)
Frame = +3
Query: 186 FENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCR 365
FE+FL ++ +KRF LEG E + ++++++ + V I++GM HRGRLN+LAN
Sbjct: 476 FEHFLHSRFVGQKRFALEGGETALAILEEILERAAGRNVHEIVVGMAHRGRLNILANTVG 535
Query: 366 KPLHQLFTQFAGL--EAEDDGSGDVKYHLGTYIERLNRVTN-KNIRLAVCANPSHLEAVD 536
K + Q+F++F G GSGDVKYHLG + R +N + I ++V NPSHLEAVD
Sbjct: 536 KDVKQIFSEFEGEIDPGSTQGSGDVKYHLGA--TGMRRTSNGREIVVSVSPNPSHLEAVD 593
Query: 537 PVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
PVV G R +Q GD E ++V+ +L+HGDAAFAGQGVV
Sbjct: 594 PVVEGIVRPKQDRLGDTERERVIPVLIHGDAAFAGQGVV 632
Score = 47.2 bits (107), Expect = 4e-04
Identities = 20/31 (64%), Positives = 24/31 (77%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS L Y+T GTIH + NNQIGFTT P
Sbjct: 634 ETLNLSQLEGYSTGGTIHLIINNQIGFTTLP 664
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/42 (50%), Positives = 24/42 (57%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERN 127
LREIL L Q YC IG E+M I EQ W++QRM N
Sbjct: 414 LREILETLRQTYCGKIGCEYMNIQVPEQKRWLQQRMEPEANN 455
>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Anaeromyxobacter sp. Fw109-5
Length = 940
Score = 145 bits (351), Expect = 1e-33
Identities = 74/178 (41%), Positives = 104/178 (58%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N + + KR +L ++ + E +L K+ KRF +EG E L+P + +D + G
Sbjct: 183 NRVSLEPEVKRRLLEKVVEAETLEQYLGTKFLGAKRFSVEGAEGLLPLFELAVDRAIGHG 242
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVT 479
V ++++GM HRGRLNVLANV KPL +F +F + G GDVKYHLG Y
Sbjct: 243 VRNVVIGMAHRGRLNVLANVVGKPLRDIFAEFRDAAIINAGGGDVKYHLG-YSSDRESAE 301
Query: 480 NKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ L++ NPSHLE +D VV G+ RA+Q D + + + IL+HGDAAFA QGVV
Sbjct: 302 GVLVHLSLAFNPSHLEWIDTVVQGRVRAKQDRYRDTDRHRSLPILVHGDAAFAAQGVV 359
Score = 43.2 bits (97), Expect = 0.007
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
E++ +S+L Y GTIH + NNQ+GFTT P
Sbjct: 361 ESLQMSELEGYAVGGTIHVIVNNQVGFTTSP 391
Score = 39.1 bits (87), Expect = 0.11
Identities = 18/49 (36%), Positives = 28/49 (57%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKDER*PE 148
LR ++ RLE+ YC +G+E ++ + W+ QRM T RN+ PE
Sbjct: 143 LRGLVARLEETYCRTLGVELAHMHDADLRGWLEQRMERT-RNRVSLEPE 190
>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
Rhodopirellula baltica
Length = 969
Score = 144 bits (350), Expect = 2e-33
Identities = 75/179 (41%), Positives = 109/179 (60%), Gaps = 1/179 (0%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N ++ + +R I RL +T FE F+ +K+ K F LEG E LIP + ++ + +
Sbjct: 222 NRLDLSHEVQRRIYTRLADATIFEEFVRRKFVGAKTFSLEGAESLIPLIDLALEKAGQHQ 281
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAE-DDGSGDVKYHLGTYIERLNRV 476
V+ ++M M HRGRLNV+AN+ +K +F F E G GDV+YHLG Y
Sbjct: 282 VKEVVMAMAHRGRLNVMANILKKRAMNIFWSFDDPTPELSRGGGDVRYHLG-YSSDWKTA 340
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ + +++C NPSHLE V+ V G+TR +Q RGD + + VM+IL+HGDAAFAG+GVV
Sbjct: 341 SGDRLHISLCFNPSHLEYVNTVALGRTRCKQDNRGDVDRQDVMTILIHGDAAFAGEGVV 399
Score = 47.2 bits (107), Expect = 4e-04
Identities = 19/31 (61%), Positives = 24/31 (77%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS+L Y T GT+H V NNQ+GFTT P
Sbjct: 401 ETLNLSELKGYRTGGTLHVVINNQVGFTTEP 431
Score = 42.7 bits (96), Expect = 0.009
Identities = 17/41 (41%), Positives = 27/41 (65%)
Frame = +2
Query: 11 ILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKD 133
ILN+L+ YC +IG +FM I++ +W+++RM TE D
Sbjct: 185 ILNKLQSTYCRSIGAQFMHIDNRNIRDWLQRRMETTENRLD 225
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Salinibacter ruber (strain DSM 13855)
Length = 1243
Score = 144 bits (350), Expect = 2e-33
Identities = 79/188 (42%), Positives = 112/188 (59%), Gaps = 10/188 (5%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N + +++ I+ +L + FE FL K+ KRF LEG E +IP + ++ + G
Sbjct: 486 NAGSPSEEERHRIVQKLNAAEAFERFLHTKYIGHKRFSLEGSETMIPLIDTLLSDAADEG 545
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG-LEAE-DDGSGDVKYHLGTYIERLNR 473
VE ++MGM HRGRLNVLAN+ KP ++F++F G ++ GSGDVKYHLG + +
Sbjct: 546 VEEVVMGMAHRGRLNVLANIIGKPYEEIFSKFEGNIDPNTTQGSGDVKYHLGAEGD-VTS 604
Query: 474 VTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGK--------KVMSILLHGDA 629
I + + +NPSHLEAV+PVV G +RA+Q D + VM +L+HGDA
Sbjct: 605 PDGNEISVTLASNPSHLEAVNPVVEGMSRAKQNLLRDEHPEAAEDDYHDAVMPLLIHGDA 664
Query: 630 AFAGQGVV 653
FAGQGVV
Sbjct: 665 GFAGQGVV 672
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/31 (67%), Positives = 24/31 (77%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++LS L YTT GT+H V NNQIGFTT P
Sbjct: 674 ETLNLSKLRGYTTGGTVHLVINNQIGFTTPP 704
Score = 37.9 bits (84), Expect = 0.26
Identities = 20/52 (38%), Positives = 29/52 (55%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKDER*PEEAH 157
LREIL+ L ++Y + +G FM I+ E+ WI+ R + RN EE H
Sbjct: 446 LREILSILRKSYTSKVGTAFMHISDPEEKTWIQNR-IEPMRNAGSPSEEERH 496
>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase E1 component, putative - Leishmania major
Length = 979
Score = 144 bits (349), Expect = 2e-33
Identities = 74/179 (41%), Positives = 113/179 (63%), Gaps = 4/179 (2%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 311
M+ +++ I + + FE+F +K+S++KRFG +G E ++ ++ +++ S++LGV++I
Sbjct: 220 MSREERLRIWDTVASAVFFEDFFKRKYSTQKRFGCDGAESMVAGLRALLEKSSELGVQAI 279
Query: 312 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAED----DGSGDVKYHLGTYIERLNRVT 479
+GM HRGRLNVL +V KP + +F G+ ++ DVKYHLG Y +L +
Sbjct: 280 NLGMAHRGRLNVLCHVIGKPFEVILKEFVGVTGQELHPFQIQSDVKYHLG-YRGQLKLNS 338
Query: 480 NKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
K + + NPSHLEAV+P V G TRA Q G+ +KV+ I +HGDAAFAGQGV F
Sbjct: 339 GKVMETEMLFNPSHLEAVNPFVQGYTRAMQVSLGEKGREKVLPIEIHGDAAFAGQGVAF 397
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/32 (59%), Positives = 23/32 (71%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
FETM +S++ T GT+H V NNQIGFTT P
Sbjct: 397 FETMCISEVGEQDTGGTVHVVCNNQIGFTTDP 428
>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Proteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 940
Score = 144 bits (348), Expect = 3e-33
Identities = 78/174 (44%), Positives = 104/174 (59%), Gaps = 1/174 (0%)
Frame = +3
Query: 135 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
+ + +R IL RLT + G E +L + +KRF LEG + LIP + +I + GV I+
Sbjct: 197 SVELQRHILERLTAAEGLERYLHTNYVGQKRFSLEGGDSLIPLLDNLILYAGSKGVGEIV 256
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGL-EAEDDGSGDVKYHLGTYIERLNRVTNKNI 491
+GM HRGRLNVL N K LF +F G E ++ SGDVKYHLG + +
Sbjct: 257 IGMAHRGRLNVLVNTLGKLPRDLFMEFEGQHETDNKRSGDVKYHLGFSAD--GDTPGGPV 314
Query: 492 RLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ + NPSHLE +DPVV G RA Q R D G +V+ +L+HGD+AFAGQGVV
Sbjct: 315 HITLAFNPSHLEIIDPVVEGSVRARQQRRKDWLGDEVIPVLIHGDSAFAGQGVV 368
Score = 37.5 bits (83), Expect = 0.35
Identities = 16/29 (55%), Positives = 20/29 (68%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET ++S + T GT+H V NNQIGFTT
Sbjct: 370 ETFNMSQSRGFFTGGTLHIVINNQIGFTT 398
>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Orientia tsutsugamushi Boryong|Rep:
2-oxoglutarate dehydrogenase, E1 component - Orientia
tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 963
Score = 140 bits (340), Expect = 3e-32
Identities = 76/171 (44%), Positives = 106/171 (61%), Gaps = 2/171 (1%)
Frame = +3
Query: 147 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 326
+ L+L L TGFE FL K+ KRF ++G E I A+ I+ + ++ +++GM
Sbjct: 216 RELLLKNLISITGFEEFLHTKFVGAKRFSIQGAEASIAAVIDAIEQAIDYCIKEVVIGMA 275
Query: 327 HRGRLNVLANVCRKPLHQLFTQFAG-LEAEDDG-SGDVKYHLGTYIERLNRVTNKNIRLA 500
HRGRL LA V +KP + + ++F + D SGDVKYH+G + N NI+++
Sbjct: 276 HRGRLVTLAEVAKKPHYAIISEFMNEVHINDKNISGDVKYHMG--YSGVYTGKNNNIKIS 333
Query: 501 VCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+ NPSHLEAV+ VV GK RA+Q D E K+VM IL+HGDAAF+GQGVV
Sbjct: 334 LTPNPSHLEAVNSVVAGKVRAKQDDLEDIERKQVMGILIHGDAAFSGQGVV 384
Score = 37.9 bits (84), Expect = 0.26
Identities = 13/45 (28%), Positives = 27/45 (60%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNKDE 136
LR ++++LEQ YC NI +EF + ++ +W+ ++ N ++
Sbjct: 168 LRTLISQLEQIYCGNIAVEFNHLTDRDEIDWLYDQLEQVSLNLND 212
Score = 33.1 bits (72), Expect = 7.5
Identities = 14/28 (50%), Positives = 18/28 (64%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFT 741
E++ LS L Y G +H + NNQIGFT
Sbjct: 386 ESLLLSALKPYAAGGILHYIINNQIGFT 413
>UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;
n=4; Paramecium tetraurelia|Rep: 2-oxoglutarate
dehydrogenase, putative - Paramecium tetraurelia
Length = 964
Score = 138 bits (334), Expect = 1e-31
Identities = 76/169 (44%), Positives = 105/169 (62%), Gaps = 5/169 (2%)
Frame = +3
Query: 165 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 344
RL R F FL ++++ KRFG+EG + LI ++ ++D + VE II+GM HRGRL+
Sbjct: 202 RLARVDLFNEFLKNRFTTSKRFGIEGTDTLIVGLEALVDQCAQNKVEHIIVGMAHRGRLS 261
Query: 345 VLANVCRKPLHQLFTQFAG-----LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCA 509
LANV +KPL +F +F +E GDVKYHLG ++ +IR+ +
Sbjct: 262 TLANVFKKPLEIIFAEFQNKYSKEIEESWGNIGDVKYHLGVTRDQ-QFPDGHHIRMTMLP 320
Query: 510 NPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
NPSHLEAV+PVV GKTRA Q G+ + + I++HGDAA AGQGVV+
Sbjct: 321 NPSHLEAVNPVVQGKTRALQDICGNKQ--NCLGIIIHGDAAMAGQGVVY 367
Score = 43.2 bits (97), Expect = 0.007
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+E++ L +L Y+ G IH V NNQIGFTT P
Sbjct: 367 YESLQLENLTGYSNEGVIHVVVNNQIGFTTTP 398
Score = 37.9 bits (84), Expect = 0.26
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
+REI +RL Q Y G+E++ + S EQ +W+ Q M
Sbjct: 148 IREIYDRLSQIYTKKYGVEYIHMVSTEQKHWVEQEM 183
>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase subunit, putative - Trypanosoma brucei
Length = 1008
Score = 137 bits (332), Expect = 2e-31
Identities = 71/175 (40%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 311
++ +++ IL + +S GFE F+ K+ ++ RFGL+G E L+PA+ ++ ++ LGV S
Sbjct: 219 LSKEERIHILDDVVKSCGFETFIQLKYGTQLRFGLDGAEALVPAVIALMQEASDLGVTSF 278
Query: 312 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGS--GDVKYHLGTYIERLNRVTNK 485
+ GMPHRGRLN+LANV KPL + +F G + + GD KYHLG ++ K
Sbjct: 279 VQGMPHRGRLNLLANVKVKPLTDILAEFEGKTHRNAIARLGDNKYHLGA-DRQIELRNGK 337
Query: 486 NIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGV 650
I + NPSHLEA++P+V GK RA D+E + + I+ HGDAA +G G+
Sbjct: 338 VINFDLLCNPSHLEAMNPLVLGKARARMVVEKDSECVRTLPIIAHGDAAISGLGM 392
Score = 40.7 bits (91), Expect = 0.037
Identities = 17/29 (58%), Positives = 20/29 (68%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ETM L DL Y GT+H + NNQ+GFTT
Sbjct: 395 ETMGLWDLDNYRVGGTVHIITNNQVGFTT 423
Score = 33.1 bits (72), Expect = 7.5
Identities = 14/48 (29%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVAT--ERNKDER 139
L++I+ +L+ YC +IG EF+ + +W + ++ T +K+ER
Sbjct: 177 LQQIVEKLQMMYCGSIGFEFLLTEGDDVRHWFHKEILKTFEPLSKEER 224
>UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=20; Bacillaceae|Rep: 2-oxoglutarate dehydrogenase E1
component - Bacillus anthracis
Length = 955
Score = 137 bits (332), Expect = 2e-31
Identities = 78/182 (42%), Positives = 109/182 (59%), Gaps = 12/182 (6%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
++ +L RLT GFE FL K + +KRF +EG ++L+P + +++ K GVE +++GM
Sbjct: 189 KRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGM 248
Query: 324 PHRGRLNVLANVCRKPLHQLFTQF-----AGLEAEDDGSGDVKYHLGTYIERLNRVTNKN 488
HRGRL+VLA+V KP +F +F G A +GDVKYHLG R V+N+
Sbjct: 249 AHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAVANSGWTGDVKYHLG----REQVVSNEE 304
Query: 489 I--RLAVCANPSHLEAVDPVVXGKTRAEQFYR-----GDNEGKKVMSILLHGDAAFAGQG 647
+ R+ + NPSHLE V+PVV G RA Q R + + K IL+HGDAAF GQG
Sbjct: 305 VSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLPEQDTSKSFVILVHGDAAFPGQG 364
Query: 648 VV 653
+V
Sbjct: 365 IV 366
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/29 (65%), Positives = 23/29 (79%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET++LS L AY T GTIH +ANN +GFTT
Sbjct: 368 ETLNLSRLNAYQTGGTIHVIANNAVGFTT 396
>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=5; Enterobacteriaceae|Rep: 2-oxoglutarate
dehydrogenase E1 component - Escherichia coli (strain
UTI89 / UPEC)
Length = 939
Score = 137 bits (331), Expect = 3e-31
Identities = 71/162 (43%), Positives = 98/162 (60%)
Frame = +3
Query: 165 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 344
+L + E +L ++ +KRF LEG E IPA+ + GVE +++GM HRGRLN
Sbjct: 207 KLMAAETLERYLHTRYVGQKRFSLEGGESAIPALDTLTKRLRAQGVEEMVIGMAHRGRLN 266
Query: 345 VLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHL 524
VL N+ K QLF +F G + GSGDVKYH+G Y L ++ +A+ NPSHL
Sbjct: 267 VLVNLLNKDPAQLFAEFEGKQTIGSGSGDVKYHMG-YSSNLETPAG-SLHVALAYNPSHL 324
Query: 525 EAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGV 650
E V+PVV G+ RA Q RG++ KV+ +L+HGD+A G GV
Sbjct: 325 EIVNPVVLGQVRARQERRGEDGQAKVVGVLIHGDSALGGLGV 366
Score = 38.7 bits (86), Expect = 0.15
Identities = 17/28 (60%), Positives = 19/28 (67%)
Frame = +1
Query: 661 TMHLSDLPAYTTHGTIHXVANNQIGFTT 744
T +LS Y T GT+H V NNQIGFTT
Sbjct: 370 TFNLSQTQGYGTGGTLHLVINNQIGFTT 397
>UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Oxoglutarate
dehydrogenase - Dictyostelium discoideum AX4
Length = 900
Score = 137 bits (331), Expect = 3e-31
Identities = 69/173 (39%), Positives = 104/173 (60%), Gaps = 3/173 (1%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
+K IL L +S F+ F+ KK+ + KR+GLEG E ++ + + S K ++++++GM
Sbjct: 141 EKINILKNLIKSEIFDQFMQKKFPTFKRYGLEGNESMMVSCDSIFRESAKNQLKNVVIGM 200
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGS---GDVKYHLGTYIERLNRVTNKNIR 494
PHRGRLN+L +C P F + G +G GDV H+ + +++
Sbjct: 201 PHRGRLNLLVQMCNYPAKDFFWKVKGNSEFSEGILGVGDVTSHIAVSTDLQFNNNKESVH 260
Query: 495 LAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+++ NPSHLEAVDPV GKTRA+QFY + G + + ++LHGDAA AGQGVV
Sbjct: 261 VSLIHNPSHLEAVDPVAAGKTRAKQFYEKNEGGSESLCLMLHGDAAVAGQGVV 313
Score = 39.5 bits (88), Expect = 0.086
Identities = 16/31 (51%), Positives = 20/31 (64%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET+ LS L + G +H + NNQIGFTT P
Sbjct: 315 ETLQLSQLSGFNIGGCVHVIVNNQIGFTTVP 345
>UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=7; Chlamydiaceae|Rep: 2-oxoglutarate dehydrogenase E1
component - Chlamydophila abortus
Length = 908
Score = 136 bits (328), Expect = 7e-31
Identities = 72/165 (43%), Positives = 97/165 (58%), Gaps = 2/165 (1%)
Frame = +3
Query: 168 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 347
+ ++T FE FL K++ +KRF LEGCE L+ ++ ++ + S I+GM HRGRLNV
Sbjct: 175 ICKATFFEEFLQVKFTGQKRFSLEGCESLVSMLEHLVRYGVTQNITSYILGMAHRGRLNV 234
Query: 348 LANVCRKPLHQLFTQFAGLEAED--DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSH 521
L NV KP Q+F +F D GDVKYH G Y+ R + + + NPSH
Sbjct: 235 LTNVLGKPYSQVFMEFEDNPQFRGLDTVGDVKYHKG-YVSRSFGQHGEEVTFVMLPNPSH 293
Query: 522 LEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
LEAVDPVV G A Q + ++IL+HGDAAF+GQGVV+
Sbjct: 294 LEAVDPVVEGVVAALQHQVDAGKEHSCLAILVHGDAAFSGQGVVY 338
Score = 47.2 bits (107), Expect = 4e-04
Identities = 17/32 (53%), Positives = 24/32 (75%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+ LS +P Y+T GT+H + NN IGFT +P
Sbjct: 338 YETLQLSQIPGYSTGGTLHIIVNNHIGFTAQP 369
>UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Acidobacteria bacterium Ellin345|Rep:
2-oxoglutarate dehydrogenase, E1 component -
Acidobacteria bacterium (strain Ellin345)
Length = 820
Score = 135 bits (327), Expect = 1e-30
Identities = 65/169 (38%), Positives = 103/169 (60%), Gaps = 1/169 (0%)
Frame = +3
Query: 150 RLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPH 329
R +L L R+ FE L ++ KR+ LEG LIP + ++++ + + G E +M M H
Sbjct: 92 RRVLDALVRADMFEQTLQSRYIGTKRYSLEGNTSLIPLLHEILNAAAEHGAEQAVMAMSH 151
Query: 330 RGRLNVLANVCRKPLHQLFTQFAGLEAEDD-GSGDVKYHLGTYIERLNRVTNKNIRLAVC 506
RGRLNV+ NV +P ++F F ++ G GDVKYH+G+ + + + + + +
Sbjct: 152 RGRLNVIVNVVNRPAAEIFAGFEDVDPRSVLGGGDVKYHIGSTGD-YHAANGQTVHIHLA 210
Query: 507 ANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
+NPSHLEAV+PV G+ +A+Q G+ KV+ +++HGD AFAGQG+V
Sbjct: 211 SNPSHLEAVNPVAAGRVKAKQQRIGEGGIPKVVPLIMHGDTAFAGQGIV 259
Score = 41.1 bits (92), Expect = 0.028
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++L LP + GT+H +ANN IGFT P
Sbjct: 261 ETLNLEHLPGFDIGGTVHVIANNLIGFTANP 291
>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
decarboxylase - Plesiocystis pacifica SIR-1
Length = 927
Score = 135 bits (326), Expect = 1e-30
Identities = 70/172 (40%), Positives = 106/172 (61%), Gaps = 1/172 (0%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
D++ +L+ L ++FL K+ KRF + G E LIP + +I+ + + + +I G
Sbjct: 178 DEQVRLLSSLINVDTVDHFLHSKFLGAKRFSISGAESLIPLLDCLIEGAAEHDIGEVIFG 237
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAED-DGSGDVKYHLGTYIERLNRVTNKNIRL 497
M HRGRLNVL N+ K ++F +F+ +AE G+GDVKYHLG Y T+++I L
Sbjct: 238 MAHRGRLNVLMNILGKAPKEVFEEFSNTDAESYIGAGDVKYHLG-YHRYHKTSTDRDIYL 296
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
A+ NPSHLEA+ PV+ G+ RA+Q + +++ +HGDAAF+GQGVV
Sbjct: 297 ALAFNPSHLEAITPVIQGRVRAKQDANPERGHAASLAVTMHGDAAFSGQGVV 348
Score = 39.9 bits (89), Expect = 0.065
Identities = 15/36 (41%), Positives = 23/36 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LREI+ RL YC ++G+E+ + Q W++QRM
Sbjct: 131 LREIIERLRNTYCRHVGVEYWHLYDPAQRAWLQQRM 166
Score = 36.7 bits (81), Expect = 0.61
Identities = 16/31 (51%), Positives = 20/31 (64%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
ET++++ L Y G I V NNQIGFTT P
Sbjct: 350 ETLNMAALEGYEAGGVIRVVINNQIGFTTDP 380
>UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Enterobacteriaceae|Rep: 2-oxoglutarate
dehydrogenase E1 component - Buchnera aphidicola subsp.
Schizaphis graminum
Length = 923
Score = 134 bits (325), Expect = 2e-30
Identities = 77/170 (45%), Positives = 98/170 (57%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
+K L + FE +L KK+S KRF LEG E LI + ++I S K V II+GM
Sbjct: 192 EKIRFLKEILYGETFEKYLGKKFSGTKRFSLEGGETLISILHEIIRYSKKNDVSEIILGM 251
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAV 503
HRGRLNVL NV K LF +F+G+ + SGDVKYH+G + N K I L +
Sbjct: 252 AHRGRLNVLVNVLNKNPQVLFNEFSGINIPKEYSGDVKYHMGGITKIKN--DKKKIYLKL 309
Query: 504 CANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
NPSHLE V+PVV G RA +E K +SI +HGDA+ GQGV+
Sbjct: 310 AYNPSHLEIVNPVVLGIARASINQLKISE-NKFLSINIHGDASIIGQGVI 358
Score = 41.1 bits (92), Expect = 0.028
Identities = 18/29 (62%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+++S AY GTIH V NNQIGFTT
Sbjct: 360 ETLNMSQTEAYKIGGTIHIVINNQIGFTT 388
Score = 33.1 bits (72), Expect = 7.5
Identities = 11/36 (30%), Positives = 22/36 (61%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
+R++ +L YC +IG E+M+I + + WI + +
Sbjct: 144 IRDLYEQLNNKYCGSIGFEYMYIENSFEKKWITKHI 179
>UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1
subunit; n=3; cellular organisms|Rep: Predicted
2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus
tauri
Length = 1210
Score = 134 bits (324), Expect = 2e-30
Identities = 76/175 (43%), Positives = 103/175 (58%), Gaps = 8/175 (4%)
Frame = +3
Query: 147 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 326
+R LARL R+ ENFLA+++ S KRFGLEG E LIP ++ ++ + + VESI++GMP
Sbjct: 217 RRKTLARLLRADMLENFLAERFPSAKRFGLEGAESLIPGLQAFVERAAERRVESIVLGMP 276
Query: 327 HRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIE---RLNRVTNKNIRL 497
HRGRLNVL NV KPL + + + GDV+YHLG + + + +
Sbjct: 277 HRGRLNVLHNVFGKPLGAISAEIVD-DRSSFLVGDVRYHLGARARVDVEIEEGEKRPVTM 335
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYR-----GDNEGKKVMSILLHGDAAFAGQG 647
+ NPSHLE V+ VV G RA+QF R G V+ +LLHGDA+F G G
Sbjct: 336 TLVPNPSHLEMVNAVVSGVVRAKQFRRDPEAQGAGARAHVLPLLLHGDASFCGLG 390
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/31 (64%), Positives = 23/31 (74%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
E M L DLP Y+T GT+H + NNQIGFTT P
Sbjct: 394 EVMTLQDLPDYSTGGTVHVIVNNQIGFTTVP 424
>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component
, putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
dehydrogenase E1 component , putative - Babesia bovis
Length = 891
Score = 132 bits (319), Expect = 9e-30
Identities = 73/184 (39%), Positives = 106/184 (57%), Gaps = 4/184 (2%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + + + + R+ FE F K + + KRFG +G E I A+ + ++S
Sbjct: 132 PGAMDFSKEDRLNFFRSIARAVTFERFCTKAFPTVKRFGADGIESSILAVDVLSEMSMAF 191
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE-AEDDGS---GDVKYHLGTYIER 464
GV+S+IMGM HRGRLN+L NV +PL ++F +F G +GS GDVKYH G +R
Sbjct: 192 GVDSLIMGMSHRGRLNMLVNVLNRPLEEMFAEFRGKNWYATEGSEYCGDVKYHFGYSSKR 251
Query: 465 LNRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQ 644
N+ + + NPSHL+ V PVV GK RA Q + E +V+ ++LHGDAAF+G+
Sbjct: 252 ------GNLHVDMLNNPSHLQFVHPVVAGKARARQVI-SNLESTRVLPVVLHGDAAFSGE 304
Query: 645 GVVF 656
GV +
Sbjct: 305 GVTY 308
Score = 45.6 bits (103), Expect = 0.001
Identities = 19/32 (59%), Positives = 24/32 (75%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+ +S +P YT GTI+ V NNQIGFTT P
Sbjct: 308 YETVQMSRIPEYTVGGTINIVVNNQIGFTTYP 339
>UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Neorickettsia sennetsu str.
Miyayama|Rep: 2-oxoglutarate dehydrogenase, E1 component
- Neorickettsia sennetsu (strain Miyayama)
Length = 905
Score = 131 bits (317), Expect = 2e-29
Identities = 73/173 (42%), Positives = 98/173 (56%), Gaps = 3/173 (1%)
Frame = +3
Query: 147 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 326
K +L L R G E F+ K+ + KRF +EGC+ + A++ +I+V+ G +I+GM
Sbjct: 178 KLALLDVLIRVNGLEEFVNTKFRAVKRFSVEGCDTALVALESIIEVAANAGCTDVIVGMS 237
Query: 327 HRGRLNVLANVCRKPLHQLFTQFAG---LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRL 497
HRGRLN L N K LF F G E GDVKYH G ER ++ K I
Sbjct: 238 HRGRLNSLVNTFGKKYRALFHGFEGKSPFPEECKIHGDVKYHYGFSCERKTFLSEKTIFA 297
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+ NPSHL++VDPV+ G RA + + G V +LLHGDAAF+GQGVV+
Sbjct: 298 RLLHNPSHLDSVDPVLVGAARAAK-----DSGAVVFPVLLHGDAAFSGQGVVY 345
Score = 45.6 bits (103), Expect = 0.001
Identities = 19/32 (59%), Positives = 23/32 (71%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ETM L +LP Y + G IH + NNQIGFTT P
Sbjct: 345 YETMLLEELPNYESGGVIHIILNNQIGFTTSP 376
Score = 32.7 bits (71), Expect = 9.9
Identities = 9/36 (25%), Positives = 22/36 (61%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
+ +I+ + YC +IG++FM ++ + W+ +R+
Sbjct: 128 VEQIVCEMHAVYCGHIGVQFMHLSDNSEVTWLEERL 163
>UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus
oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus
oryzae
Length = 453
Score = 131 bits (317), Expect = 2e-29
Identities = 72/173 (41%), Positives = 104/173 (60%), Gaps = 1/173 (0%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
++KR +L L R+T +E F+A K+ +EKRFGL+G E IPA++ ID S + GV+ I MG
Sbjct: 179 EEKRRMLHGLVRATSWEKFVATKFPNEKRFGLDGVESYIPALETAIDRSAEHGVDKIEMG 238
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDG-SGDVKYHLGTYIERLNRVTNKNIRL 497
+ HRGR+N+L N+ K +F F G GD+KYH G ER+ + K + +
Sbjct: 239 VAHRGRMNMLYNIVGKDGASMFRDFDPKGTSSWGIPGDIKYHYGGSGERVT-PSGKKVYM 297
Query: 498 AVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
V PSHL++V+PV GKTR Q D E + M + +H DA+FA QG ++
Sbjct: 298 NVLPQPSHLDSVNPVAMGKTRGIQDRLAD-ERESTMMLNVHTDASFAAQGTIY 349
Score = 46.0 bits (104), Expect = 0.001
Identities = 18/34 (52%), Positives = 25/34 (73%)
Frame = +1
Query: 643 RASCFETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
+ + +ET+ LS LP YTT GT+ + NNQ+GFTT
Sbjct: 345 QGTIYETLGLSGLPGYTTGGTLRVIVNNQVGFTT 378
Score = 44.4 bits (100), Expect = 0.003
Identities = 17/43 (39%), Positives = 30/43 (69%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATERNK 130
L E++ E+ YC+ +GIE+M I++ EQ +WIR R+ +R++
Sbjct: 133 LWEVIAACEKTYCSTMGIEYMHISNQEQVDWIRARIEGAQRHR 175
>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase
E1 component - Staphylococcus aureus
Length = 932
Score = 129 bits (312), Expect = 6e-29
Identities = 77/197 (39%), Positives = 112/197 (56%), Gaps = 17/197 (8%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P +N ++KR + +L GFE +L K + KRF +EG + L+P +++ I ++ K
Sbjct: 172 PYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKE 231
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE----AEDDGS--------GDVKY 440
G+++I +GM HRGRLNVL +V KP + ++F + +DGS GDVKY
Sbjct: 232 GIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKY 291
Query: 441 HLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQ--FYRG---DNEGKKVM 605
HLG + T + R+A+ NPSHLE V PVV G+TRA Q R + K M
Sbjct: 292 HLGGIKTTDSYGTMQ--RIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAM 349
Query: 606 SILLHGDAAFAGQGVVF 656
I++HGDAA+ GQG+ F
Sbjct: 350 PIIIHGDAAYPGQGINF 366
Score = 46.8 bits (106), Expect = 6e-04
Identities = 18/32 (56%), Positives = 25/32 (78%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
FETM+L +L Y+T G++H + NN+IGFTT P
Sbjct: 366 FETMNLGNLKGYSTGGSLHIITNNRIGFTTEP 397
>UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=8; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Geobacillus kaustophilus
Length = 950
Score = 128 bits (309), Expect = 1e-28
Identities = 76/191 (39%), Positives = 115/191 (60%), Gaps = 19/191 (9%)
Frame = +3
Query: 138 ADQKRL-ILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
A+++R+ +L RLT GFE F+ + + +KRF +EG + ++P + +++ + + ++++
Sbjct: 191 ANKERVALLRRLTEVEGFEKFIHRTYVGQKRFSIEGLDSMVPLLDELVRQAIEHEIDAVN 250
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAED----DGS--------GDVKYHLGTYI 458
+GM HRGRLNVLA+V KP +F +F E+++ +GS GDVKYHLG
Sbjct: 251 IGMAHRGRLNVLAHVLGKPYEMIFAEFQHAESKNFIPSEGSVAITYGWTGDVKYHLGA-A 309
Query: 459 ERLNRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKV------MSILLH 620
RL + +R+ + NPSHLE V+PVV G TRA Q R G V +IL+H
Sbjct: 310 RRLRNQSAHTMRITLANNPSHLEVVNPVVLGYTRAAQEDR-TKPGVPVQNTDASFAILIH 368
Query: 621 GDAAFAGQGVV 653
GDAAF GQG+V
Sbjct: 369 GDAAFPGQGIV 379
Score = 46.4 bits (105), Expect = 8e-04
Identities = 20/29 (68%), Positives = 23/29 (79%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET++LS L YTT GTIH +ANN IGFTT
Sbjct: 381 ETLNLSQLRGYTTGGTIHIIANNMIGFTT 409
>UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Oxoglutarate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 901
Score = 128 bits (308), Expect = 2e-28
Identities = 68/182 (37%), Positives = 101/182 (55%), Gaps = 4/182 (2%)
Frame = +3
Query: 120 NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLG 299
N K+ K+ L+ LT++ E F+ ++ KRF +EG + ++P M +++ T
Sbjct: 151 NPAKLALADKKDALSSLTKAETLEKFVHTRYVGTKRFSVEGADSILPMMDTLVNKGTAQQ 210
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG----LEAEDDGSGDVKYHLGTYIERL 467
V+ + +GM HRGR+N+L N KP +F F G E +D DVKYHLG E+
Sbjct: 211 VQEVFVGMAHRGRVNILVNFFGKPEEYVFGDFNGPLELAEPIEDFDNDVKYHLGYVTEK- 269
Query: 468 NRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQG 647
+ ++ + NPSHLE V+ V G RA Q G + K V+ +L+HGDAAFAGQG
Sbjct: 270 -KTPTGTCKVTLAYNPSHLETVNAVALGMARAAQDQIGASGKKNVVPVLIHGDAAFAGQG 328
Query: 648 VV 653
+V
Sbjct: 329 IV 330
Score = 36.7 bits (81), Expect = 0.61
Identities = 13/29 (44%), Positives = 23/29 (79%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+ ++ + +++T GTIH + +NQ+GFTT
Sbjct: 332 ETLQMAGVHSHSTGGTIHIIIDNQVGFTT 360
>UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E1 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 933
Score = 128 bits (308), Expect = 2e-28
Identities = 64/170 (37%), Positives = 98/170 (57%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
+K+ IL L +ST +ENF+ KK+ KRF LEGC+ L+P +K++I+ + I +GM
Sbjct: 196 KKKNILKNLIKSTVYENFINKKFPGTKRFSLEGCDSLLPMIKEIINFCLNKKITKIFLGM 255
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAV 503
HRGRLNV+ N+ + +F +GDVKYH+G +++ V N+ + + +
Sbjct: 256 AHRGRLNVMHNILKHNTLNMFLNIQDKLCHSHRTGDVKYHIG--LKKKIFVNNQEVEINL 313
Query: 504 CANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
NPSHLE + PVV G + F + +++HGDAAF GQGV+
Sbjct: 314 LNNPSHLEIITPVVIGCCKF--FIENKKTIISPLPVIIHGDAAFTGQGVI 361
Score = 40.7 bits (91), Expect = 0.037
Identities = 16/29 (55%), Positives = 22/29 (75%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+++S +PAY G+IH V NN+I FTT
Sbjct: 363 ETLNMSQVPAYNVFGSIHIVINNKIAFTT 391
>UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Bacillus sp. B14905|Rep: Alpha-ketoglutarate
decarboxylase - Bacillus sp. B14905
Length = 670
Score = 127 bits (307), Expect = 3e-28
Identities = 77/191 (40%), Positives = 108/191 (56%), Gaps = 17/191 (8%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 311
+++D+K+ +L RLTR FE F+ K + +KRF EG + I ++I + L VE +
Sbjct: 196 LSSDEKKALLDRLTRVENFEKFIHKTFVGQKRFSGEGLDTQIVLFDEIIKTAEALSVEKV 255
Query: 312 IMGMPHRGRLNVLANVCRKPLHQLFTQFA------------GLEAEDDGSGDVKYHLGTY 455
+GM HRGRLNVL ++ KP +F+ FA LE +GDVKYH+G
Sbjct: 256 RIGMAHRGRLNVLTHILNKPYDMMFSDFAHVSNDLFMPENGRLEITKGWTGDVKYHMGA- 314
Query: 456 IERLNRVTNKNIRLAVCANPSHLEAVDPVVXGKTRAEQF-----YRGDNEGKKVMSILLH 620
NR + N++LA NPSHLE +PVV G TRA Q + ++ K + IL+H
Sbjct: 315 --SYNRDSGMNVKLAY--NPSHLEVGNPVVLGATRATQDDTSKPGQAIHDRTKGLGILVH 370
Query: 621 GDAAFAGQGVV 653
GDAAF GQG+V
Sbjct: 371 GDAAFPGQGIV 381
Score = 37.9 bits (84), Expect = 0.26
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
E ++ + +TT GTIH +ANN IGFTT
Sbjct: 383 EVLNFAKTEGFTTGGTIHIIANNMIGFTT 411
>UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1
component - Anaplasma marginale (strain St. Maries)
Length = 930
Score = 125 bits (301), Expect = 1e-27
Identities = 66/174 (37%), Positives = 108/174 (62%), Gaps = 3/174 (1%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
++KR L L + FE FL ++ KRF +EG ++L+P ++++I ++ + +++G
Sbjct: 195 ERKRETLRCLQETELFEQFLHVRYPGYKRFSVEGGDVLVPLLERIIALAPGFNCKEVVLG 254
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDG---SGDVKYHLGTYIERLNRVTNKNI 491
+ HRGRL+VL V RKP + +F+G A +G SGDVKYHLG + ++ + +
Sbjct: 255 LSHRGRLSVLTRVMRKPYAAVLYEFSGGMAYPEGLSLSGDVKYHLGYSTD--TKIGGETV 312
Query: 492 RLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
L++ N S LE+V+PVV G+ +A + D + + V+ IL+HG+AAF GQGVV
Sbjct: 313 HLSLAYNSSSLESVNPVVMGRVKA----KSDEKRQPVLGILVHGNAAFIGQGVV 362
Score = 41.5 bits (93), Expect = 0.021
Identities = 18/41 (43%), Positives = 26/41 (63%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMVATER 124
L IL L++ YC +IG EFM I S E+ +W+R ++ T R
Sbjct: 150 LPSILQALKETYCGSIGYEFMHIPSSEERDWLRDKIENTSR 190
Score = 33.9 bits (74), Expect = 4.3
Identities = 14/31 (45%), Positives = 18/31 (58%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
E LS + Y+ G +H V NNQ+GFT P
Sbjct: 364 EGFTLSGVAGYSPGGIVHVVVNNQVGFTADP 394
>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Dichelobacter nodosus VCS1703A|Rep:
2-oxoglutarate dehydrogenase, E1 component -
Dichelobacter nodosus (strain VCS1703A)
Length = 917
Score = 124 bits (299), Expect = 2e-27
Identities = 71/181 (39%), Positives = 110/181 (60%), Gaps = 8/181 (4%)
Frame = +3
Query: 132 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 311
++A Q+ +L +L + FE +L +++ +KRF LEG + LIP + Q+I G + +
Sbjct: 180 ISAAQQHELLTQLIAADRFEQYLHQRYVGQKRFSLEGGDALIPLLNQLIMELAHNGAQQL 239
Query: 312 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDG-SGDVKYHLGTYIERLNRVTNKN 488
+ M HRGRLNVLA+V KP ++F +F G A +GDVKYHLG + R+ + ++
Sbjct: 240 CLAMAHRGRLNVLAHVLGKPAARIFAEFEGQTASAAPINGDVKYHLG-FTARV-QYQAQS 297
Query: 489 IRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEG-------KKVMSILLHGDAAFAGQG 647
++L++ NPSHLE V+ V G RA+ + + EG KV+ IL+HGDAA +GQG
Sbjct: 298 VQLSLMYNPSHLEFVNAVALGFARAQLEHCSEKEGATIMAAADKVVPILIHGDAALSGQG 357
Query: 648 V 650
+
Sbjct: 358 I 358
Score = 37.1 bits (82), Expect = 0.46
Identities = 16/29 (55%), Positives = 18/29 (62%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
E + LS L Y G +H V NNQIGFTT
Sbjct: 361 EVLQLSQLRGYFCGGAVHIVVNNQIGFTT 389
>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
dehydrogenase E1 component - Blochmannia floridanus
Length = 970
Score = 123 bits (297), Expect = 4e-27
Identities = 74/184 (40%), Positives = 101/184 (54%), Gaps = 14/184 (7%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVST-KLGVESIIMG 320
++R L L S E +L K+ KRF LEG ++LIP +K+ I S ++ I +G
Sbjct: 212 EQRQFLNELIASEELERYLGIKFPGSKRFSLEGGDVLIPMLKEAIRYSVLNHNIQEIFLG 271
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLA 500
MPHRGRLN L NV K LF +F G + SGDVKYH G Y E + ++ + ++
Sbjct: 272 MPHRGRLNTLINVLGKNPQDLFNEFYGTNQKYTNSGDVKYHQGLYSE--VTINSQIVHIS 329
Query: 501 VCANPSHLEAVDPVVXGKTRA--EQFYRGD------NEGKK-----VMSILLHGDAAFAG 641
+ NPSHLE + PV+ G RA EQ Y+ N+ K V+ I +HGDAA +
Sbjct: 330 LLFNPSHLEIITPVMMGAARARIEQLYKDQIHKTILNKNYKIQQNIVLPITIHGDAAISA 389
Query: 642 QGVV 653
QGVV
Sbjct: 390 QGVV 393
Score = 41.1 bits (92), Expect = 0.028
Identities = 17/29 (58%), Positives = 23/29 (79%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+++++ AY+ GTIH V NNQIGFTT
Sbjct: 395 ETLNMANTRAYSVGGTIHIVINNQIGFTT 423
Score = 33.1 bits (72), Expect = 7.5
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIR 100
L I L++ YC IGIE+M I + Q WI+
Sbjct: 162 LNSIYKFLKKTYCGTIGIEYMHILDINQILWIQ 194
>UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 974
Score = 122 bits (295), Expect = 7e-27
Identities = 70/185 (37%), Positives = 108/185 (58%), Gaps = 12/185 (6%)
Frame = +3
Query: 135 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 314
+A+++R + + S F++FLA K+++ KR+G EG E ++ ++ S+ GV I+
Sbjct: 160 SAEERRRLAKVMLESQEFDHFLAAKFATVKRYGGEGAESMMGFFYELFHQSSHSGVTDIV 219
Query: 315 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGS---GDVKYHLGTYIERLNRVTNK 485
+GMPHRGRLN+L + + P +F + GL D S GDV HL + +E L+ +
Sbjct: 220 IGMPHRGRLNLLTGLLKFPPELMFRKMRGLSEFPDSSPAIGDVLSHLTSSVE-LDFGAGR 278
Query: 486 NIRLAVCANPSHLEAVDPVVXGKTRAEQFYR--GD-------NEGKKVMSILLHGDAAFA 638
+ + + NPSHLEA+DPV GKTRA Q R GD G +V+ + +HGD +F
Sbjct: 279 PLHVTMLPNPSHLEAIDPVAQGKTRARQQLRKEGDYSPEDAAQPGDQVICLQVHGDGSFT 338
Query: 639 GQGVV 653
GQG+V
Sbjct: 339 GQGIV 343
Score = 40.3 bits (90), Expect = 0.049
Identities = 16/29 (55%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET+ LS LP Y G+IH + NNQ+G+TT
Sbjct: 345 ETLTLSKLPHYRVGGSIHLIVNNQVGYTT 373
>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
putative; n=2; Theileria|Rep: 2-oxoglutarate
dehydrogenase e1 component, putative - Theileria parva
Length = 1030
Score = 121 bits (292), Expect = 2e-26
Identities = 62/179 (34%), Positives = 97/179 (54%), Gaps = 3/179 (1%)
Frame = +3
Query: 129 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVES 308
K N + + ++ FE F AK + + KRFG++G E ++ ++ + + G+ S
Sbjct: 216 KFNKNDHLKCFKSICKAVKFEQFCAKTFPTLKRFGMDGIESILLLLESIEENGRNFGINS 275
Query: 309 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE---AEDDGSGDVKYHLGTYIERLNRVT 479
I+M M HRGRLNVL N KPL + F +F G SGDVKYH G R T
Sbjct: 276 IMMTMSHRGRLNVLCNFLNKPLQESFAEFRGANWFINSHFRSGDVKYHNG------YRTT 329
Query: 480 NKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+ + + +N SHL+ PV+ G +A+Q+Y D K++ I +HG++A +GQG+ +
Sbjct: 330 KNGVEIQMISNSSHLQFSHPVLTGLVKAKQYYENDTNQSKILPIAIHGNSAISGQGMPY 388
>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Coxiella burnetii
Length = 934
Score = 121 bits (292), Expect = 2e-26
Identities = 66/195 (33%), Positives = 106/195 (54%)
Frame = +3
Query: 129 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVES 308
+ + + KR IL +L + E +L K+ + R+ LEG + LIP + ++ + +E
Sbjct: 192 EFDKETKRNILQQLVTAESLEKYLDTKYVGQVRYSLEGGDSLIPLLDELTKRARHQKIEE 251
Query: 309 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKN 488
I++ M HRGR+NVL N+ + +LF +F G + SGDVKYH G R +
Sbjct: 252 IVICMAHRGRVNVLLNIMGQSAAELFQEFEGKKDYGLMSGDVKYHRG--YSRDVKTDAGP 309
Query: 489 IRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVFRDDA 668
I L++ NPSHLE + PV G RA Q + ++ M++++HGDA+F+G+G+V +
Sbjct: 310 IHLSLAFNPSHLEFICPVAMGSVRARQERQNGHKRDYAMTVMIHGDASFSGEGIVM-EAL 368
Query: 669 PVGPARLHHARDHTH 713
+ R HH H
Sbjct: 369 SMSQTRAHHVGGSIH 383
Score = 38.3 bits (85), Expect = 0.20
Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 4/50 (8%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIR----QRMVATERNKDER 139
L+EI RL + YC +IG+++ I+ + NW+R QR+ + E +K+ +
Sbjct: 149 LKEIYTRLREIYCGSIGVQYSTISDERERNWLRDYVEQRLPSIEFDKETK 198
Score = 33.5 bits (73), Expect = 5.7
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
E + +S A+ G+IH + NNQ+GFTT
Sbjct: 366 EALSMSQTRAHHVGGSIHIILNNQVGFTT 394
>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr13 scaffold_17, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 973
Score = 120 bits (289), Expect = 4e-26
Identities = 78/180 (43%), Positives = 101/180 (56%)
Frame = +3
Query: 117 PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKL 296
P + N ++ +IL RL ST FENFLA KW++ KRFGLE
Sbjct: 229 PTPRQYNQQRREVILDRLIWSTQFENFLATKWTAAKRFGLE------------------- 269
Query: 297 GVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRV 476
G E++I GM V P+ + GL G+GDVKYHLGT +R R
Sbjct: 270 GGETLIPGMKEMFDRAADLGVESIPVDDV-----GLYT---GTGDVKYHLGTSYDRPTR- 320
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
+ I L++ ANPSHLEAVDPVV GKTRA+Q+Y D + K + +L+HGD +FAGQGVV+
Sbjct: 321 GGRRIHLSLVANPSHLEAVDPVVVGKTRAKQYYSNDLDRTKNIGVLIHGDGSFAGQGVVY 380
Score = 52.4 bits (120), Expect = 1e-05
Identities = 22/32 (68%), Positives = 25/32 (78%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+ET+HLS LP YTT GTIH V NNQ+ FTT P
Sbjct: 380 YETLHLSALPNYTTGGTIHIVVNNQVAFTTDP 411
Score = 50.8 bits (116), Expect = 4e-05
Identities = 20/36 (55%), Positives = 27/36 (75%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LR IL RLEQAYC +IG E+M I ++CNW+R ++
Sbjct: 191 LRAILTRLEQAYCGSIGYEYMHIADRDKCNWLRDKI 226
>UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Burkholderiaceae|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Burkholderia phymatum STM815
Length = 891
Score = 116 bits (280), Expect = 5e-25
Identities = 68/173 (39%), Positives = 100/173 (57%), Gaps = 3/173 (1%)
Frame = +3
Query: 144 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 323
++ +L RL +E +A + KRF LEGCE L+P + +I+ S GV+ I +GM
Sbjct: 165 ERDALLRRLLTVEMWERLVASRHGHAKRFSLEGCESLVPLLDALIESSAIDGVQQIFLGM 224
Query: 324 PHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSG---DVKYHLGTYIERLNRVTNKNIR 494
PHRGRLN L N+ P+ ++ A L+ E D + D+ YHLG L R + I
Sbjct: 225 PHRGRLNALVNLMDFPVAEM---LACLDHESDIAAMQTDLPYHLGG--AALKRTAHGEIA 279
Query: 495 LAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVV 653
L + NPSHL++V PVV G RA ++ ++ + +++HGDAAFAGQG+V
Sbjct: 280 LLLAHNPSHLQSVYPVVSGMARA---WQDEHLDAACVPVVVHGDAAFAGQGIV 329
Score = 39.5 bits (88), Expect = 0.086
Identities = 16/29 (55%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET++++ YT GTIH + NNQIGFTT
Sbjct: 331 ETLNMTRKSGYTLGGTIHVIVNNQIGFTT 359
>UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase
domain-containing protein 1; n=39; Eumetazoa|Rep:
Dehydrogenase E1 and transketolase domain-containing
protein 1 - Homo sapiens (Human)
Length = 919
Score = 115 bits (276), Expect = 1e-24
Identities = 64/183 (34%), Positives = 106/183 (57%), Gaps = 12/183 (6%)
Frame = +3
Query: 141 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 320
++++ + + S F++FLA K+S+ KR+G EG E ++ +++ +S G+ +I+G
Sbjct: 161 EERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIG 220
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD---GSGDVKYHLGTYIERLNRVTNKNI 491
MPHRGRLN+L + + P +F + GL + +GDV HL + ++ L + +
Sbjct: 221 MPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVD-LYFGAHHPL 279
Query: 492 RLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNE---------GKKVMSILLHGDAAFAGQ 644
+ + NPSHLEAV+PV GKTR Q R D + G +V+ + +HGDA+F GQ
Sbjct: 280 HVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQ 339
Query: 645 GVV 653
G+V
Sbjct: 340 GIV 342
Score = 37.5 bits (83), Expect = 0.35
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
ET LS+LP + G++H + NNQ+G+TT
Sbjct: 344 ETFTLSNLPHFRIGGSVHLIVNNQLGYTT 372
>UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family
protein - Tetrahymena thermophila SB210
Length = 1004
Score = 108 bits (260), Expect = 1e-22
Identities = 70/190 (36%), Positives = 112/190 (58%), Gaps = 8/190 (4%)
Frame = +3
Query: 123 VTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGV 302
+T++ + +K I + L+++ ++FL KK+ + KR+ EG E I +K ++ ++++GV
Sbjct: 202 LTELTSFEKVNIHSLLSQTEALDHFLHKKFQTFKRYAGEGAESSIVGLKTILAKASEMGV 261
Query: 303 ESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG---LEAE-DDGSGDVKYHLGTYIE-RL 467
E ++GMPHRGRLNVL N+ P+ L + +G L E + DV H+ + +L
Sbjct: 262 EDAVIGMPHRGRLNVLCNLLDYPVADLLRKISGHPDLPNELYNYIDDVVSHIAVSKKGKL 321
Query: 468 NRVT---NKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFA 638
T + I +++ NPSHLEAV+PV GK RA+ + E V++I LHGDAAF+
Sbjct: 322 YAGTGCKERPINVSLLHNPSHLEAVNPVSMGKARAKMDEKTKTE---VLNIQLHGDAAFS 378
Query: 639 GQGVVFRDDA 668
QGVV+ A
Sbjct: 379 AQGVVYESFA 388
Score = 41.9 bits (94), Expect = 0.016
Identities = 16/32 (50%), Positives = 22/32 (68%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
+E+ L +P ++ GTIH + NNQIGFTT P
Sbjct: 384 YESFALGKVPKFSVGGTIHMIVNNQIGFTTNP 415
>UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p -
Drosophila melanogaster (Fruit fly)
Length = 919
Score = 107 bits (257), Expect = 3e-22
Identities = 59/172 (34%), Positives = 99/172 (57%), Gaps = 11/172 (6%)
Frame = +3
Query: 168 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 347
L +S ++NF+A K+ + KR+G EG E ++ Q++ S + +E +++ MPHRGR +
Sbjct: 172 LIKSQAWDNFMALKFPTVKRYGGEGAESMLAFFWQLLRDSVQANIEHVVLAMPHRGRTPL 231
Query: 348 LANVCRKPLHQLFTQFAGLE--AED-DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPS 518
A + ++F + G +ED + DV H ++ ++ K + ++ NPS
Sbjct: 232 QAALLNMRPAKVFRKLGGASEFSEDIEAMSDVISHF--HVSEQLKILGKKLSFSMVRNPS 289
Query: 519 HLEAVDPVVXGKTRAEQFYRGDNE--------GKKVMSILLHGDAAFAGQGV 650
HLEA +PV GKTR++Q RG+ G+ V++++LHGDAAFAGQG+
Sbjct: 290 HLEAANPVAMGKTRSKQQARGEGAFGDGSQPFGEHVLNVILHGDAAFAGQGI 341
Score = 33.9 bits (74), Expect = 4.3
Identities = 11/29 (37%), Positives = 21/29 (72%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
E ++++ +P + G++H + NNQ+GFTT
Sbjct: 344 ECLNMAYVPHFEVGGSLHLIVNNQVGFTT 372
>UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3;
Bilateria|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 911
Score = 104 bits (250), Expect = 2e-21
Identities = 62/180 (34%), Positives = 96/180 (53%), Gaps = 13/180 (7%)
Frame = +3
Query: 168 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 347
+ + F+ FL+ K+ + KR+G EG E + ++ + + + VE II+G+ HRGRLN+
Sbjct: 160 MLKCENFDKFLSTKFPTLKRYGAEGAESMFAFFSELFEGAAEKQVEEIIIGIAHRGRLNL 219
Query: 348 LANVCRKPLHQLFTQFAG---LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPS 518
L + P +F + G D +GDV HL + + + + N+ + + NPS
Sbjct: 220 LTQLMDFPPVHMFRKIKGRAEFPESADAAGDVLSHLVSSFD--YKGSEGNVHVTMLPNPS 277
Query: 519 HLEAVDPVVXGKTRAE--QFYRGD--------NEGKKVMSILLHGDAAFAGQGVVFRDDA 668
HLEAV+PV GK RA +GD G V+++L+HGD AF GQGVV+ A
Sbjct: 278 HLEAVNPVAMGKARARAWSMNKGDYSPDERSARAGDSVLNVLVHGDGAFTGQGVVWESIA 337
Score = 36.7 bits (81), Expect = 0.61
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM---VATERNKDE 136
L ++ +L YC IEFM IN+ E+ WI Q +A E K+E
Sbjct: 105 LHDLAEQLRHIYCGPTAIEFMHINNWEERQWISQNFENCIAEELRKEE 152
Score = 33.9 bits (74), Expect = 4.3
Identities = 14/29 (48%), Positives = 19/29 (65%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFT 741
+E++ LS P + GT+H V NNQI FT
Sbjct: 333 WESIALSQAPHFRLGGTVHLVTNNQIAFT 361
>UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 893
Score = 103 bits (247), Expect = 5e-21
Identities = 59/167 (35%), Positives = 98/167 (58%), Gaps = 4/167 (2%)
Frame = +3
Query: 168 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 347
L + +++ KK+++ KR+ EG E +I A++ + + +LGV ++ M HRGR +
Sbjct: 153 LVQMEAIDHYYHKKFTTFKRYAGEGGEGVIVALRAIYGQAVELGVTDVVQSMAHRGRFPL 212
Query: 348 LANVCRKPLHQLFTQFAG---LEAE-DDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANP 515
++++ P +F + G L E G DV +HL T + NK++ + V NP
Sbjct: 213 MSSLLDFPPSDIFRKIMGENDLPQEYTFGVDDVVHHLST--SNKKKFNNKDLTITVVHNP 270
Query: 516 SHLEAVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVF 656
SHLEA +PV GK +A+Q G+ + +V+++ LHGDAAFAGQG+V+
Sbjct: 271 SHLEAANPVSQGKAKAKQDDYGNID--QVLNLQLHGDAAFAGQGIVY 315
Score = 39.5 bits (88), Expect = 0.086
Identities = 16/30 (53%), Positives = 22/30 (73%)
Frame = +1
Query: 655 FETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
+E+M LS L Y+ GT+H + NNQIG+TT
Sbjct: 315 YESMLLSGLDNYSNGGTVHIIQNNQIGYTT 344
>UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;
Aspergillus|Rep: Contig An06c0020, complete genome -
Aspergillus niger
Length = 456
Score = 81.4 bits (192), Expect = 2e-14
Identities = 51/121 (42%), Positives = 69/121 (57%), Gaps = 2/121 (1%)
Frame = +3
Query: 300 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGS-GDVKYHLGTYIERLNRV 476
+E I MG+ HRGR+N L N+ K + F E G GDVKYH G R+
Sbjct: 1 MELIEMGLGHRGRMNALYNIVGKDGPSMLRDFDSKETSAWGMRGDVKYHYGGSGARVTP- 59
Query: 477 TNKNIRLAVCANPSHLEAVDPVVXGKTRAEQFYR-GDNEGKKVMSILLHGDAAFAGQGVV 653
+ + + + + PS++E+V+PVV GKTRA Q R GD E K M + +H DAAFAGQ V
Sbjct: 60 SGRKVYMNMAPQPSNVESVNPVVMGKTRAIQDRRNGDRE--KTMMLNVHTDAAFAGQKTV 117
Query: 654 F 656
+
Sbjct: 118 Y 118
>UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 730
Score = 77.4 bits (182), Expect = 4e-13
Identities = 50/116 (43%), Positives = 63/116 (54%), Gaps = 7/116 (6%)
Frame = +3
Query: 321 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGT--YIERLNRVTNKNIR 494
M HRGRLNVL NV KPL + + + GDV+YHLG ++ K +
Sbjct: 1 MAHRGRLNVLHNVFGKPLGAICAEIVD-DRSSFLVGDVRYHLGARAVVDVDVERGAKQVA 59
Query: 495 LAVCANPSHLEAVDPVVXGKTRAEQFYR-GDNEGKK----VMSILLHGDAAFAGQG 647
L + NPSHLE V+ VV G RA+QF R EG V+ +LLHGDA+F G G
Sbjct: 60 LTLVPNPSHLEMVNAVVSGVVRAKQFKRDSQTEGASARAHVLPLLLHGDASFCGLG 115
Score = 50.8 bits (116), Expect = 4e-05
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +1
Query: 658 ETMHLSDLPAYTTHGTIHXVANNQIGFTTRP 750
E M L DLP YTT GT+H V NNQIGFTT P
Sbjct: 119 EVMQLQDLPDYTTGGTVHVVVNNQIGFTTVP 149
>UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura
dioica|Rep: CG1544-PA-like protein - Oikopleura dioica
(Tunicate)
Length = 886
Score = 69.7 bits (163), Expect = 7e-11
Identities = 47/160 (29%), Positives = 81/160 (50%), Gaps = 6/160 (3%)
Frame = +3
Query: 186 FENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCR 365
F+ FLA ++ KR+GLEG E ++ +++ K + +GM HRGR N+L +
Sbjct: 166 FDEFLALRFPDVKRYGLEGSETIMLWFDTILNEVDK--DNHVTIGMTHRGRNNLLVCLLG 223
Query: 366 KPLHQLFTQFAG-----LEAEDDGS-GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLE 527
+F + +G + E + GDV HL +++ + + +++ NPSHL+
Sbjct: 224 LRADIMFGKMSGKPEFPFDPEHEKIIGDVLSHL-----QISSTLDSGVSVSLLPNPSHLD 278
Query: 528 AVDPVVXGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQG 647
A++P GK R++ + G K + I HGD + GQG
Sbjct: 279 AINPAAMGKARSKM-----DHGGKALCIQCHGDGSLIGQG 313
>UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 334
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/44 (59%), Positives = 34/44 (77%)
Frame = +3
Query: 129 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIP 260
K + D+KR IL RL S+ FE+FLA K+ ++KRFGLEGCE L+P
Sbjct: 261 KYSIDEKRRILDRLIWSSSFESFLATKYPNDKRFGLEGCETLVP 304
Score = 43.2 bits (97), Expect = 0.007
Identities = 16/36 (44%), Positives = 25/36 (69%)
Frame = +2
Query: 2 LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRM 109
LREI+ E+ YC + G+E++ I EQC+W+R R+
Sbjct: 219 LREIIAACERIYCGSYGVEYIHIPDREQCDWLRARI 254
>UniRef50_UPI0000E46CA4 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 244
Score = 38.7 bits (86), Expect = 0.15
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 640 VRASCFETMHLSDLPAYTTHGTIHXVANNQIGFTT 744
V A CF +++LP Y G+IH + NNQIGFTT
Sbjct: 38 VIAECFA---MANLPHYAVGGSIHLIVNNQIGFTT 69
Score = 35.9 bits (79), Expect = 1.1
Identities = 14/21 (66%), Positives = 18/21 (85%)
Frame = +3
Query: 591 GKKVMSILLHGDAAFAGQGVV 653
G KV+++LLHGDAAF QGV+
Sbjct: 19 GDKVINVLLHGDAAFVAQGVI 39
>UniRef50_Q9KJ66 Cluster: Irb5; n=1; Vibrio cholerae|Rep: Irb5 -
Vibrio cholerae
Length = 53
Score = 37.1 bits (82), Expect = 0.46
Identities = 16/27 (59%), Positives = 19/27 (70%)
Frame = +3
Query: 489 IRLAVCANPSHLEAVDPVVXGKTRAEQ 569
+ LA+ NPSHLE V+PVV G RA Q
Sbjct: 1 VHLALAFNPSHLEIVNPVVMGSVRARQ 27
>UniRef50_A3Z1Y0 Cluster: Serine protease, subtilase family protein;
n=1; Synechococcus sp. WH 5701|Rep: Serine protease,
subtilase family protein - Synechococcus sp. WH 5701
Length = 692
Score = 35.5 bits (78), Expect = 1.4
Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Frame = -2
Query: 617 QQDRHHLLALVVSPVELLGSGLAXHHGVDGLQVRGVRANSQSNVLVGNAIQTLDVR-AQV 441
Q DR+ + L + VE L + L+ H+G+ V + +NS+ L+ +I T+ R AQ+
Sbjct: 404 QLDRYVAVNLTRAEVETLAASLSQHYGIASPAVYRMFSNSKKKALISESIHTVQARTAQL 463
Query: 440 IFHVAG 423
++ G
Sbjct: 464 GYNAYG 469
>UniRef50_Q1MRZ5 Cluster: Hyphotheical protein; n=1; Lawsonia
intracellularis PHE/MN1-00|Rep: Hyphotheical protein -
Lawsonia intracellularis (strain PHE/MN1-00)
Length = 554
Score = 34.7 bits (76), Expect = 2.5
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +3
Query: 288 TKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERL 467
T+ + +II P R +V++ C++P + F L D+GSGD+ + +R+
Sbjct: 127 TEQAIINIIATAPSGHRKSVISAFCQEPFNIFEKNFNKLRGSDEGSGDLSHTKLKVAQRV 186
Query: 468 -NRVTNKNI 491
R+T K I
Sbjct: 187 AARITQKKI 195
>UniRef50_A5DBM7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1112
Score = 33.1 bits (72), Expect = 7.5
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Frame = +3
Query: 309 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKN 488
++ G P G+ ++ ++ L + F Q L D S +++ H TY+ + V ++
Sbjct: 612 MLAGPPGTGKTSLAKSIANS-LGRSF-QRVSLGGIKDES-EIRGHRRTYVGAMPGVIIQS 668
Query: 489 IRLAVCANP-SHLEAVDPVVXGKTRAEQFYRGD 584
+R A C NP L+ +D V+ G + A +F GD
Sbjct: 669 LRKARCMNPVILLDEIDKVIGGNSNANKF-NGD 700
>UniRef50_Q14197 Cluster: Immature colon carcinoma transcript 1
protein precursor; n=25; Deuterostomia|Rep: Immature
colon carcinoma transcript 1 protein precursor - Homo
sapiens (Human)
Length = 206
Score = 33.1 bits (72), Expect = 7.5
Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 12/149 (8%)
Frame = +3
Query: 93 GSDSAW*PPNVTKMNADQKRLILARLT----RST--GFENFLAKKWSSEKRFGLEGCEIL 254
GSD+AW PN K AD + L RLT RS+ G +N +E RF L E +
Sbjct: 54 GSDTAWRVPNGAK-QADSD-IPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLATAEWI 111
Query: 255 IPAMKQVIDVSTKLGV----ESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDG 422
++Q I ++ K + E I+ R + LA+ C + + + T+ A ++
Sbjct: 112 AEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLAD-CLQKIRDMITE-ASQTPKEPT 169
Query: 423 SGDVKYHLGTYIERLN--RVTNKNIRLAV 503
DVK H IE +N R+ K I AV
Sbjct: 170 KEDVKLH-RIRIENMNRERLRQKRIHSAV 197
>UniRef50_Q2NB23 Cluster: Protein-tyrosine-phosphatase; n=6;
Alphaproteobacteria|Rep: Protein-tyrosine-phosphatase -
Erythrobacter litoralis (strain HTCC2594)
Length = 157
Score = 32.7 bits (71), Expect = 9.9
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 4/38 (10%)
Frame = +3
Query: 348 LANVCRKPLHQLF----TQFAGLEAEDDGSGDVKYHLG 449
L N+CR PL + + AGL+AE D +G YH+G
Sbjct: 12 LGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVG 49
>UniRef50_Q029Y8 Cluster: NHL repeat containing protein; n=2;
Bacteria|Rep: NHL repeat containing protein - Solibacter
usitatus (strain Ellin6076)
Length = 380
Score = 32.7 bits (71), Expect = 9.9
Identities = 14/20 (70%), Positives = 16/20 (80%)
Frame = -2
Query: 479 GNAIQTLDVRAQVIFHVAGT 420
GNA+ +DVRA IFHVAGT
Sbjct: 260 GNAVYRMDVRAGKIFHVAGT 279
>UniRef50_A5V064 Cluster: Putative uncharacterized protein; n=2;
Roseiflexus|Rep: Putative uncharacterized protein -
Roseiflexus sp. RS-1
Length = 251
Score = 32.7 bits (71), Expect = 9.9
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -2
Query: 674 DRCIVSKHDALTSERRVAVQQDRHHLLALVVSPVELLGSGLAXHH-GVD-GLQVRGVRAN 501
D V +HD ++R V ++ D HL+ + + L + L HH +D LQ+ + +
Sbjct: 75 DATFVFRHDPAVAQRPVRIRHDAEHLILESMKRRQNLQAALPYHHITLDTSLQLSPLTSG 134
Query: 500 SQSNVLV 480
+SNV++
Sbjct: 135 RESNVIL 141
>UniRef50_Q9ST86 Cluster: CAA303711.1 protein; n=2; Oryza
sativa|Rep: CAA303711.1 protein - Oryza sativa (Rice)
Length = 764
Score = 32.7 bits (71), Expect = 9.9
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = +1
Query: 361 AVSLCTSCSHSSPVSKLRMMVP 426
AV+LC +CSH SPVS LR P
Sbjct: 352 AVTLCRACSHLSPVSPLRSKPP 373
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 777,638,104
Number of Sequences: 1657284
Number of extensions: 16369687
Number of successful extensions: 52075
Number of sequences better than 10.0: 87
Number of HSP's better than 10.0 without gapping: 49429
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51903
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61734884250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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