Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30299
(722 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 351 1e-96
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 351 1e-96
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 351 1e-96
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 351 1e-96
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 351 1e-96
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 351 2e-96
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 350 3e-96
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 349 5e-96
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 348 1e-95
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 329 7e-90
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 329 7e-90
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 329 7e-90
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 329 7e-90
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 312 1e-84
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 284 2e-76
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 186 5e-47
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 7.3
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 7.3
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 351 bits (864), Expect = 1e-96
Identities = 162/221 (73%), Positives = 191/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 351 bits (864), Expect = 1e-96
Identities = 162/221 (73%), Positives = 191/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 351 bits (864), Expect = 1e-96
Identities = 162/221 (73%), Positives = 191/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 351 bits (864), Expect = 1e-96
Identities = 162/221 (73%), Positives = 191/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 351 bits (864), Expect = 1e-96
Identities = 162/221 (73%), Positives = 191/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 351 bits (862), Expect = 2e-96
Identities = 161/221 (72%), Positives = 192/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 350 bits (861), Expect = 3e-96
Identities = 161/221 (72%), Positives = 191/221 (86%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 349 bits (859), Expect = 5e-96
Identities = 162/221 (73%), Positives = 190/221 (85%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFK 224
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 348 bits (856), Expect = 1e-95
Identities = 161/221 (72%), Positives = 190/221 (85%), Gaps = 2/221 (0%)
Frame = +2
Query: 65 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 244
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 245 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 424
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 425 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 598
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 599 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
N D SI DFAHSSF+ AL + +PLYLSTKNTILK YDGRFK
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKIYDGRFK 224
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 329 bits (808), Expect = 7e-90
Identities = 154/225 (68%), Positives = 180/225 (80%), Gaps = 2/225 (0%)
Frame = +2
Query: 53 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 229
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 230 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 409
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 410 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVA 586
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 587 LAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
+ M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFK
Sbjct: 219 MGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFK 263
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 329 bits (808), Expect = 7e-90
Identities = 154/225 (68%), Positives = 180/225 (80%), Gaps = 2/225 (0%)
Frame = +2
Query: 53 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 229
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 230 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 409
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 410 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVA 586
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 587 LAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
+ M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFK
Sbjct: 219 MGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFK 263
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 329 bits (808), Expect = 7e-90
Identities = 154/225 (68%), Positives = 180/225 (80%), Gaps = 2/225 (0%)
Frame = +2
Query: 53 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 229
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 230 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 409
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 410 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVA 586
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 587 LAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
+ M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFK
Sbjct: 219 MGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFK 263
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 329 bits (808), Expect = 7e-90
Identities = 154/225 (68%), Positives = 180/225 (80%), Gaps = 2/225 (0%)
Frame = +2
Query: 53 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 229
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 230 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 409
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 410 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVA 586
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 587 LAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFK 721
+ M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFK
Sbjct: 219 MGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFK 263
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 312 bits (765), Expect = 1e-84
Identities = 143/195 (73%), Positives = 169/195 (86%), Gaps = 2/195 (1%)
Frame = +2
Query: 143 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 322
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 323 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 502
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 503 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYL 676
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 677 STKNTILKKYDGRFK 721
STKNTILKKYDGRFK
Sbjct: 181 STKNTILKKYDGRFK 195
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 284 bits (697), Expect = 2e-76
Identities = 129/189 (68%), Positives = 152/189 (80%), Gaps = 1/189 (0%)
Frame = +2
Query: 158 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 337
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 338 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 517
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 518 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 694
+F P+ G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTI
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTI 221
Query: 695 LKKYDGRFK 721
LK YDGRFK
Sbjct: 222 LKAYDGRFK 230
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 186 bits (454), Expect = 5e-47
Identities = 87/125 (69%), Positives = 103/125 (82%), Gaps = 2/125 (1%)
Frame = +2
Query: 353 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 532
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 533 SG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKY 706
G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTILKKY
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKY 120
Query: 707 DGRFK 721
DGRFK
Sbjct: 121 DGRFK 125
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 7.3
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +1
Query: 415 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 585
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 586 TGYV*H*C 609
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 7.3
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +1
Query: 415 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 585
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 586 TGYV*H*C 609
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,910,734
Number of Sequences: 237096
Number of extensions: 2334185
Number of successful extensions: 4245
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4076
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4223
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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