Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30225
(630 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo... 172 7e-42
UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne... 157 2e-37
UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R... 152 8e-36
UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy... 149 7e-35
UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a... 142 5e-33
UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 142 8e-33
UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a... 139 6e-32
UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy... 137 2e-31
UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a... 134 1e-30
UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 132 9e-30
UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a... 132 9e-30
UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy... 130 4e-29
UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a... 127 3e-28
UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy... 126 4e-28
UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a... 124 2e-27
UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 122 5e-27
UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori... 121 1e-26
UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy... 120 3e-26
UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|... 119 5e-26
UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [... 119 7e-26
UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 118 9e-26
UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 117 3e-25
UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,... 114 2e-24
UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a... 105 1e-21
UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy... 102 6e-21
UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881... 100 6e-20
UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact... 98 1e-19
UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor... 96 5e-19
UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans... 96 7e-19
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18
UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 93 4e-18
UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 93 7e-18
UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 91 2e-17
UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 91 2e-17
UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:... 90 5e-17
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 90 5e-17
UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb... 89 6e-17
UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 88 2e-16
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 87 2e-16
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 87 3e-16
UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 87 3e-16
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 87 4e-16
UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 86 6e-16
UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=... 86 8e-16
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 85 1e-15
UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 85 2e-15
UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15
UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 84 2e-15
UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re... 83 4e-15
UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil... 83 4e-15
UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro... 83 7e-15
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15
UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re... 83 7e-15
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 82 9e-15
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 82 1e-14
UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb... 82 1e-14
UniRef50_Q28GY1 Cluster: Novel protein containing short chain de... 81 2e-14
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 81 2e-14
UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All... 81 2e-14
UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 81 2e-14
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 81 2e-14
UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena... 81 2e-14
UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr... 81 2e-14
UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14
UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14
UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14
UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 80 5e-14
UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 80 5e-14
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14
UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 79 7e-14
UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 79 7e-14
UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei... 79 7e-14
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 79 7e-14
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 79 7e-14
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 79 9e-14
UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14
UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 79 9e-14
UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 79 9e-14
UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 79 1e-13
UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 79 1e-13
UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13
UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13
UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 79 1e-13
UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 78 2e-13
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 78 2e-13
UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 78 2e-13
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13
UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 78 2e-13
UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 78 2e-13
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 78 2e-13
UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13
UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 78 2e-13
UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 77 3e-13
UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 77 3e-13
UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc... 77 3e-13
UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13
UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 4e-13
UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13
UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13
UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb... 77 4e-13
UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 77 5e-13
UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 77 5e-13
UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 77 5e-13
UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13
UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13
UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 77 5e-13
UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 76 6e-13
UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 76 6e-13
UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=... 76 6e-13
UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 76 6e-13
UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 76 6e-13
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 76 6e-13
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 76 6e-13
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 76 6e-13
UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 76 8e-13
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13
UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13
UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 76 8e-13
UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p... 75 1e-12
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 75 1e-12
UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 75 1e-12
UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 75 1e-12
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 75 1e-12
UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12
UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12
UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 75 1e-12
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 75 1e-12
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 75 1e-12
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 75 1e-12
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 75 1e-12
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 75 1e-12
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 75 1e-12
UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12
UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba... 75 1e-12
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 75 1e-12
UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc... 75 1e-12
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12
UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena... 75 2e-12
UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12
UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam... 75 2e-12
UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or... 75 2e-12
UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 75 2e-12
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 75 2e-12
UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 74 2e-12
UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 74 2e-12
UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 74 2e-12
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 74 2e-12
UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR... 74 2e-12
UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 74 2e-12
UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici... 74 2e-12
UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote... 74 3e-12
UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12
UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 74 3e-12
UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12
UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 74 3e-12
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 74 3e-12
UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 73 4e-12
UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR... 73 4e-12
UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo... 73 4e-12
UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro... 73 4e-12
UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 73 4e-12
UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000... 73 6e-12
UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 73 6e-12
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 73 6e-12
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 73 6e-12
UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 73 6e-12
UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 73 6e-12
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12
UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ... 73 6e-12
UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 73 6e-12
UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 73 6e-12
UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ... 73 8e-12
UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12
UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2... 73 8e-12
UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 73 8e-12
UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 72 1e-11
UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 72 1e-11
UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2... 72 1e-11
UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 72 1e-11
UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a... 72 1e-11
UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 72 1e-11
UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu... 72 1e-11
UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 72 1e-11
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena... 72 1e-11
UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 72 1e-11
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 72 1e-11
UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 72 1e-11
UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 72 1e-11
UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 71 2e-11
UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p... 71 2e-11
UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ... 71 2e-11
UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 71 2e-11
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 71 2e-11
UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 71 2e-11
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 71 2e-11
UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi... 71 2e-11
UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 71 2e-11
UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 71 2e-11
UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re... 71 2e-11
UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 71 2e-11
UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11
UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 71 3e-11
UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 71 3e-11
UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 71 3e-11
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 71 3e-11
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 71 3e-11
UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 71 3e-11
UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11
UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11
UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 71 3e-11
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 70 4e-11
UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 70 4e-11
UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 70 4e-11
UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11
UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11
UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 70 4e-11
UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 70 4e-11
UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11
UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas... 70 4e-11
UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 70 4e-11
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 70 5e-11
UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11
UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri... 70 5e-11
UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom... 70 5e-11
UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob... 70 5e-11
UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 70 5e-11
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11
UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster... 70 5e-11
UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep... 70 5e-11
UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 70 5e-11
UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13... 69 7e-11
UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 69 7e-11
UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena... 69 7e-11
UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob... 69 7e-11
UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 69 7e-11
UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 69 7e-11
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 69 7e-11
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 69 9e-11
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 69 9e-11
UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 69 9e-11
UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 69 9e-11
UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc... 69 9e-11
UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida... 69 9e-11
UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11
UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11
UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 9e-11
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11
UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein... 69 9e-11
UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 69 1e-10
UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 69 1e-10
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10
UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 69 1e-10
UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 69 1e-10
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10
UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 69 1e-10
UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 69 1e-10
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 69 1e-10
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 1e-10
UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA;... 68 2e-10
UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10
UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 68 2e-10
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 68 2e-10
UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 68 2e-10
UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 68 2e-10
UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 68 2e-10
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 68 2e-10
UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb... 68 2e-10
UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 68 2e-10
UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006... 68 2e-10
UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 68 2e-10
UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 68 2e-10
UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re... 68 2e-10
UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 68 2e-10
UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 68 2e-10
UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 68 2e-10
UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 68 2e-10
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu... 68 2e-10
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10
UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C... 68 2e-10
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat... 68 2e-10
UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=... 68 2e-10
UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 67 3e-10
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 67 3e-10
UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 67 3e-10
UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 67 3e-10
UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 67 3e-10
UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu... 67 3e-10
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 67 3e-10
UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 67 3e-10
UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc... 67 4e-10
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 67 4e-10
UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc... 67 4e-10
UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu... 67 4e-10
UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 67 4e-10
UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu... 67 4e-10
UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 67 4e-10
UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 67 4e-10
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 67 4e-10
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10
UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10
UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena... 67 4e-10
UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei... 67 4e-10
UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 67 4e-10
UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve... 67 4e-10
UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 67 4e-10
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10
UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena... 66 5e-10
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 66 5e-10
UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr... 66 5e-10
UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 66 5e-10
UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su... 66 5e-10
UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 66 5e-10
UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu... 66 5e-10
UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 66 5e-10
UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 66 5e-10
UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10
UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-10
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 66 5e-10
UniRef50_A4XEV7 Cluster: Short-chain dehydrogenase/reductase SDR... 44 6e-10
UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ... 66 7e-10
UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta... 66 7e-10
UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin... 66 7e-10
UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 66 7e-10
UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10
UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 66 7e-10
UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10
UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10
UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10
UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb... 66 7e-10
UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A... 66 7e-10
UniRef50_Q0U1A7 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10
UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=... 66 7e-10
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 66 9e-10
UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 66 9e-10
UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 66 9e-10
UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 66 9e-10
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 66 9e-10
UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10
UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 66 9e-10
UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 66 9e-10
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 66 9e-10
UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 66 9e-10
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10
UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei... 66 9e-10
UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10
UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 66 9e-10
UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 66 9e-10
UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh... 66 9e-10
UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 66 9e-10
UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena... 65 1e-09
UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 65 1e-09
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 65 1e-09
UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 65 1e-09
UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact... 65 1e-09
UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 65 1e-09
UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 65 1e-09
UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri... 65 1e-09
UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 65 1e-09
UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 65 1e-09
UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1... 65 1e-09
UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Plancto... 65 1e-09
UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_A4ET39 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 65 1e-09
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;... 65 1e-09
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 65 1e-09
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 65 1e-09
UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif... 65 2e-09
UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 65 2e-09
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_Q39N07 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_Q41CM8 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 65 2e-09
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 65 2e-09
UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 65 2e-09
UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=... 65 2e-09
UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici... 65 2e-09
UniRef50_Q14RS1 Cluster: ABA4 protein; n=4; Pezizomycotina|Rep: ... 65 2e-09
UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya... 64 2e-09
UniRef50_Q9RKB7 Cluster: Probable 3-oxoacyl-[acyl carrier protei... 64 2e-09
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 64 2e-09
UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ... 64 2e-09
UniRef50_Q3W7K4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 64 2e-09
UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;... 64 2e-09
UniRef50_A4WBV4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_A0YDM1 Cluster: Putative 3-ketoacyl-CoA reductase; n=3;... 64 2e-09
UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 64 2e-09
UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_A0GVX4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_Q75QV9 Cluster: 17-beta hydroxysteroid dehydrogenase; n... 64 2e-09
UniRef50_A0D0S7 Cluster: Chromosome undetermined scaffold_33, wh... 64 2e-09
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 64 2e-09
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000... 64 3e-09
UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 64 3e-09
UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ... 64 3e-09
UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 64 3e-09
UniRef50_Q7P5A9 Cluster: Ketoacyl reductase hetN; n=3; Fusobacte... 64 3e-09
UniRef50_Q44MJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 64 3e-09
UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q13I70 Cluster: Putative short-chain dehydrogenase/redu... 64 3e-09
UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 64 3e-09
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q0HV76 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 64 3e-09
UniRef50_A4BWQ4 Cluster: Putative short chain dehydrogenase; n=1... 64 3e-09
UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 64 3e-09
UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ... 64 3e-09
UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q9VYU9 Cluster: CG9360-PA; n=12; Diptera|Rep: CG9360-PA... 64 3e-09
UniRef50_A5DPQ3 Cluster: Putative uncharacterized protein; n=2; ... 64 3e-09
UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb... 64 3e-09
UniRef50_UPI00015B5CBB Cluster: PREDICTED: similar to ENSANGP000... 64 3e-09
UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei... 64 3e-09
UniRef50_O32291 Cluster: YxnA protein; n=4; Bacteria|Rep: YxnA p... 64 3e-09
UniRef50_Q11K25 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A3TS19 Cluster: Short-chain dehydrogenase; n=1; Janibac... 64 3e-09
UniRef50_A3PQM4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09
UniRef50_A1ZL47 Cluster: Oxidoreductase, short chain dehydrogena... 64 3e-09
UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 64 3e-09
>UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1;
Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx
mori (Silk moth)
Length = 274
Score = 172 bits (418), Expect = 7e-42
Identities = 83/198 (41%), Positives = 125/198 (63%), Gaps = 1/198 (0%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 203
DKV +TG A G+G +V+ LL E +H+A LD+A+ G +L+ +L K+G + KF +
Sbjct: 14 DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
DV DE V+ + +D VIN+AA+++ + + I++N T + STLKA++I
Sbjct: 74 DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133
Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
MG GG GG ++N+SS+ AL + +P+Y ATK+AVLQFS +G E F++T VRVL+V
Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193
Query: 564 CFGATDTALLTRRETRHF 617
C G TDTA+L + F
Sbjct: 194 CLGPTDTAILYKNNLTKF 211
>UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2;
Neoptera|Rep: Putative alcohol dehydrogenase -
Gryllotalpa orientalis (Oriental mole cricket)
Length = 266
Score = 157 bits (381), Expect = 2e-37
Identities = 80/199 (40%), Positives = 118/199 (59%), Gaps = 1/199 (0%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
K K +TG ATGIG + V+ LL GV+ +A+ D+ E G + +LN ++G K F +
Sbjct: 4 KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
DVT+++ G+D+VINNA +++DS ++ I +NVTA+ T A +
Sbjct: 64 CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121
Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
+MGK+ GG+GG V+N++S+ L P+Y ATK AV+ S G P HF +TGVRVLT
Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181
Query: 561 VCFGATDTALLTRRETRHF 617
+C G TDT L++ R F
Sbjct: 182 MCPGVTDTPLISEAHHRQF 200
>UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep:
Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 270
Score = 152 bits (368), Expect = 8e-36
Identities = 77/192 (40%), Positives = 119/192 (61%), Gaps = 1/192 (0%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
KDKV +TGAA G+G S V IL+ G K +A++D+ + G+ L+ LN +YG N+ +FY
Sbjct: 4 KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
+DV+ EE F G+L +V++ G ID++ NNA ++N+ ++K I +N+ ++ T A+E
Sbjct: 63 ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120
Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
M K +GG GG ++NV+S+A L V PIY ATK V+ FS + S GVR+
Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180
Query: 561 VCFGATDTALLT 596
+C T+LL+
Sbjct: 181 LCPWFVKTSLLS 192
>UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase - Apis mellifera
Length = 266
Score = 149 bits (360), Expect = 7e-35
Identities = 75/182 (41%), Positives = 117/182 (64%), Gaps = 1/182 (0%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
KDK V ITG A+G+G ++ R LL G IA++D AEE+GK LN ++G N+T FY
Sbjct: 4 KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
++ + F V+ GG+++++NNA + N++ + K I+VNVT++I +TL I+
Sbjct: 63 CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120
Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
M K GGKGG ++N+SS+A L + +P+Y ATK AV+ FS +P H+ +TGV++L
Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180
Query: 561 VC 566
+C
Sbjct: 181 MC 182
>UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 329
Score = 142 bits (345), Expect = 5e-33
Identities = 69/199 (34%), Positives = 115/199 (57%), Gaps = 1/199 (0%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
KDK + GA G+G + + LL GV + ++D+ E G++ LN ++G N+ F +
Sbjct: 71 KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
DVT F V G +D+++NNAA++ D + ++ I+ NVTA+ +++ ++
Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188
Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
MGK +GGKGG ++NV+SV L +PIY AT AV+ FS +P H+ +TGVR++
Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248
Query: 561 VCFGATDTALLTRRETRHF 617
+C G T++ +L + F
Sbjct: 249 LCPGLTESPMLENLKNEQF 267
>UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 261
Score = 142 bits (343), Expect = 8e-33
Identities = 70/191 (36%), Positives = 118/191 (61%), Gaps = 1/191 (0%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+KV ITG A GIG ++V+ LL+ G+K +A+ D+ K + ++L KYGN+ + Y D
Sbjct: 5 NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 383
VT++ F + V++ ID+++NNA + +D I+ + I++N A++ +L IE
Sbjct: 65 VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121
Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
+GKH GGKGG ++N +S+ L +P+Y +TK AV+ F+ C+ + TGVRV+ +
Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179
Query: 564 CFGATDTALLT 596
C G T+T L++
Sbjct: 180 CPGVTETPLVS 190
>UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 271
Score = 139 bits (336), Expect = 6e-32
Identities = 72/200 (36%), Positives = 117/200 (58%), Gaps = 8/200 (4%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKF 194
E +KV+ ITG G+G + LL+ G K +A+ D+ E G+S +L+ ++G + F
Sbjct: 2 EISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGF 61
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI------ 356
Y D+ + F N ++++ G IDV+INNA + N+ ++ + VNV + I
Sbjct: 62 YPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILR 119
Query: 357 -TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
+ L A+ MGKH GGKGG ++NV+++ L ++P Y ATK A++ F+ C+ E+F
Sbjct: 120 ASQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENF 177
Query: 534 SKTGVRVLTVCFGATDTALL 593
+ TGVRV++VC G T T L+
Sbjct: 178 ATTGVRVMSVCPGVTKTNLI 197
>UniRef50_UPI0000513348 Cluster: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase; n=2; Apis
mellifera|Rep: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase - Apis mellifera
Length = 263
Score = 137 bits (332), Expect = 2e-31
Identities = 72/204 (35%), Positives = 117/204 (57%), Gaps = 1/204 (0%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-K 185
M+ K+K ITG G+G + LL+ G K +A+LD++ G+ L ++G K
Sbjct: 1 MTDNIKNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGK 60
Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
FY DV++ F + VV + G+D+VINNA + ND +++ + +NV +I +
Sbjct: 61 AIFYACDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGS 118
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
L A + M K GGKGGT++N++S+ AL + P+Y A+K VL FS + R +++ TG
Sbjct: 119 LLAFDHMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTG 176
Query: 546 VRVLTVCFGATDTALLTRRETRHF 617
+R+L +C G T T+LL ++ F
Sbjct: 177 IRILIMCPGVTTTSLLENPLSKSF 200
>UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 279
Score = 134 bits (325), Expect = 1e-30
Identities = 70/190 (36%), Positives = 112/190 (58%), Gaps = 1/190 (0%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
KDKV+ +TG A GIG V L++G +++AILDI E +L ++G ++ Y
Sbjct: 11 KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPE--NFTADKLQEEFGTHRVDLYH 68
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
D+ +EE F V+++ +D++IN+A + N++ + ++VNV I L AIE
Sbjct: 69 CDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAIE 126
Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
MGKH GG+GG V+NV+SV L HV+P+Y A+K A++ F+ + + + GV+++
Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKIIA 184
Query: 561 VCFGATDTAL 590
VC G T T L
Sbjct: 185 VCPGHTRTKL 194
>UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 273
Score = 132 bits (318), Expect = 9e-30
Identities = 67/192 (34%), Positives = 117/192 (60%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E KDKVV ITG +GIG S+ + +L G K++A+ ++ E + + EL+ +Y ++ FY
Sbjct: 19 EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFY 78
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
DVT + + V++ ID++INNA + +D+ + ++++N+ AL+ ++ K I
Sbjct: 79 PCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFI 136
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+GKH GGKGG ++N++S+A + S +P+Y ATK V+ F+ + + TGVRVL
Sbjct: 137 ARIGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVL 193
Query: 558 TVCFGATDTALL 593
+C T+T ++
Sbjct: 194 AICPSFTNTPIV 205
>UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 266
Score = 132 bits (318), Expect = 9e-30
Identities = 74/204 (36%), Positives = 118/204 (57%), Gaps = 6/204 (2%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV--ELNSKYG-NKTKF 194
KDKV +TG GIG + V+ LL G K++AI D+ ++ ++ ++G +K F
Sbjct: 4 KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374
Y DVT + F + +V Q +D+++N A++ ++ + I++N+TA++T TL
Sbjct: 64 YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121
Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
I+ MG+H G+GG ++NV SV LT S PIY ATK V F+ + +H+ GVRV
Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179
Query: 555 LTVCFGATDTALL---TRRETRHF 617
+ VC G T+T+LL + ET +F
Sbjct: 180 MAVCPGLTETSLLHQNLKEETLNF 203
>UniRef50_UPI000051334A Cluster: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
(Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
(Prostaglandin dehydrogenase 1) isoform 1 - Apis
mellifera
Length = 264
Score = 130 bits (313), Expect = 4e-29
Identities = 63/191 (32%), Positives = 112/191 (58%), Gaps = 1/191 (0%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206
K+ +TG A GIG R LL G K +A+LD+++ G+S +LN+++G ++ F D
Sbjct: 6 KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
V+ E F V+ +++++N A +M+D+ ++ +++N ++ T+ + M
Sbjct: 66 VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123
Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
GK+ GG GG ++N+SSVA L + PIY T+ A++ F+ + ++ KTG+R+LT+C
Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181
Query: 567 FGATDTALLTR 599
G T TA+ R
Sbjct: 182 PGLTTTAMAAR 192
>UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 263
Score = 127 bits (306), Expect = 3e-28
Identities = 70/193 (36%), Positives = 115/193 (59%), Gaps = 3/193 (1%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKS-LQVE-LNSKYGN-KTKF 194
K+KV+ ITG G+ + ++LL ++IA+ D E+ + LQ++ ++G + F
Sbjct: 4 KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374
Y SDV ++ F + V++ +D++IN A ++ D+ + I+VN L+ TL A
Sbjct: 64 YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121
Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
I+ MG H GG+GGT+INVSS+ L P+Y ATK AV+ F+N + H++KTGVR
Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179
Query: 555 LTVCFGATDTALL 593
+T+C G T T+++
Sbjct: 180 MTMCPGLTSTSMI 192
>UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
(Prostaglandin dehydrogenase 1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
(Prostaglandin dehydrogenase 1) - Tribolium castaneum
Length = 312
Score = 126 bits (304), Expect = 4e-28
Identities = 66/188 (35%), Positives = 107/188 (56%), Gaps = 1/188 (0%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
V ITG A GIG ++ R+ L G+ +A+ D ++E G+ +L ++G NK F+ D+
Sbjct: 54 VAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLACEFGENKVLFFDGDM 113
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
+ + F + + +++V+NNA +MND ++ + N++ I TL ++ M
Sbjct: 114 SQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLSGTIIGTLLGMQYMS 171
Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCF 569
K S G+GGT+INV+S+ L S PI+ T+ ++ FS IG HF +TGVRV +C
Sbjct: 172 KTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLNHFDRTGVRVTALCP 231
Query: 570 GATDTALL 593
G T+T LL
Sbjct: 232 GLTNTKLL 239
>UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 267
Score = 124 bits (299), Expect = 2e-27
Identities = 73/196 (37%), Positives = 116/196 (59%), Gaps = 4/196 (2%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKT 188
E K+KV +TG GIG V+ L+ ++ +AI+D+ + EA + +LN ++G +
Sbjct: 2 EIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGS 61
Query: 189 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
++Y D+T+ + F I V+ + +D++IN A ++ND+ I VN TA++ S+
Sbjct: 62 YQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSS 119
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ AIE M K GGKGG V+NV+S+A + PIY ATK AV+ F+ + +P H G
Sbjct: 120 MIAIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIG 177
Query: 546 VRVLTVCFGATDTALL 593
VRV+ +C G TDT L+
Sbjct: 178 VRVVCICPGVTDTGLV 193
>UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep:
CG4899-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 278
Score = 122 bits (295), Expect = 5e-27
Identities = 63/193 (32%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT-KFY 197
++ K +TG A GIG V + LL G +AI+D+ + + V+L + + ++
Sbjct: 20 FRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEF--VKLRAAHPTQSVMII 77
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
+ DV +++ + + G ID+V+N A + ND ++ + VN+ +I STL A+
Sbjct: 78 KMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINSTLSAL 135
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
MGK +GGKGG V+N+SSV L ++P+Y ATK+ ++ F+ C+ +++ ++G++ +
Sbjct: 136 PYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFV 195
Query: 558 TVCFGATDTALLT 596
TVC GAT T + T
Sbjct: 196 TVCPGATMTDMFT 208
>UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx
mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk
moth)
Length = 289
Score = 121 bits (292), Expect = 1e-26
Identities = 76/198 (38%), Positives = 105/198 (53%), Gaps = 2/198 (1%)
Frame = +3
Query: 3 LNMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG- 179
L +E + KVV ITGAA GIG ++ L G K I ILDI G ELN KYG
Sbjct: 25 LKKENEIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGK 84
Query: 180 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 359
NK +F D+T + I + ++ +DV++NNA + + +K + N A I
Sbjct: 85 NKAEFIECDITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIE 140
Query: 360 STLKAIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
+LK +E M K GKGGT+IN++S P Y TK A++ FS +G ++
Sbjct: 141 FSLKFMENMRKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYK 200
Query: 537 KTGVRVLTVCFGATDTAL 590
K GVRVLT+C G T+T L
Sbjct: 201 KNGVRVLTICPGETNTTL 218
>UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase (NAD+), partial;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to 15-hydroxyprostaglandin dehydrogenase (NAD+),
partial - Strongylocentrotus purpuratus
Length = 298
Score = 120 bits (289), Expect = 3e-26
Identities = 66/189 (34%), Positives = 108/189 (57%), Gaps = 2/189 (1%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
V ITGAA G G++ LL V+ I I+D GK+ + ELN KYG +K +F++ DV
Sbjct: 46 VALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGEDKVRFFQCDV 105
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
+ ++ + ++ GID+V NNA + D + ++K ++V++ A++ T A + M
Sbjct: 106 SSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRGTFLAKQYMD 163
Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSKTGVRVLTVC 566
K+ GG+GG VIN++S+A L + P Y A K VL FS + + F+ VR+ +C
Sbjct: 164 KNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNPENVRLNCLC 223
Query: 567 FGATDTALL 593
++TA+L
Sbjct: 224 PSFSETAIL 232
>UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4;
Endopterygota|Rep: ENSANGP00000013280 - Anopheles
gambiae str. PEST
Length = 183
Score = 119 bits (287), Expect = 5e-26
Identities = 67/183 (36%), Positives = 96/183 (52%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K+KV +TGAATG+G + LL G K + I D+ +AG+ EL +YG + F
Sbjct: 4 KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
DVTD F V +++VINNA +MND+ ++ ++VN+ I TL A +
Sbjct: 63 DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120
Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
M K G GG ++N+ S ++T PIY ATK A+L + G P H + T VR
Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180
Query: 564 CFG 572
C G
Sbjct: 181 CPG 183
>UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase
[NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin
dehydrogenase [NAD+] - Homo sapiens (Human)
Length = 266
Score = 119 bits (286), Expect = 7e-26
Identities = 62/189 (32%), Positives = 108/189 (57%), Gaps = 1/189 (0%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206
KV +TGAA GIG + LL +G K +A++D EAG + L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182
Query: 567 FGATDTALL 593
G +TA+L
Sbjct: 183 PGFVNTAIL 191
>UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 337
Score = 118 bits (285), Expect = 9e-26
Identities = 63/197 (31%), Positives = 108/197 (54%), Gaps = 1/197 (0%)
Frame = +3
Query: 3 LNMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG- 179
L +S K V ITG A G+G + L G I I+DI + AGK + + +G
Sbjct: 37 LEISGVVSGKNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGV 96
Query: 180 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 359
K F +DV+ + V+ +D+V+NNA ++++ +++ I VN+ +I+
Sbjct: 97 GKVIFIHADVSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMIS 154
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
L +++ MG+ GG+GG ++NV+ + + +P+Y ATK A++ S + P + +
Sbjct: 155 VALLSMQYMGRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTER 214
Query: 540 TGVRVLTVCFGATDTAL 590
TGVRV+T+C G T+TAL
Sbjct: 215 TGVRVITLCPGLTETAL 231
>UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to
hydroxyprostaglandin dehydrogenase 15 (NAD); n=2;
Tribolium castaneum|Rep: PREDICTED: similar to
hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium
castaneum
Length = 479
Score = 117 bits (281), Expect = 3e-25
Identities = 61/197 (30%), Positives = 108/197 (54%), Gaps = 2/197 (1%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-K 185
M + +KV I+GAA+GIG ++ + LL G++ + I D+ +E G+ E+ +++G+ +
Sbjct: 1 MPFDINNKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGR 60
Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
F +DV+ + F + ID+++N A ++NDSI +++ I +NV +
Sbjct: 61 AIFVLTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGI 118
Query: 366 LKAIE-IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
L A+E + K+ G ++N SS+A + PIY TK A+ + G H+ +T
Sbjct: 119 LLALENYIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERT 178
Query: 543 GVRVLTVCFGATDTALL 593
VR++ +C G TDT LL
Sbjct: 179 KVRIMAICPGPTDTPLL 195
Score = 93.5 bits (222), Expect = 4e-18
Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%)
Frame = +3
Query: 75 VVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDVTDEEHFLGILNAVV 251
+VR G + I DI E G+ + E+ +++G NK + +DVT + + +
Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292
Query: 252 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 428
+ +D+V+N A ++N+ +++ +++N+ + T+ A+E + K+ G G ++N+
Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350
Query: 429 SSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDT 584
SS A L PIY TK AV+ S G H+ +T VRVLT C G T+T
Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402
>UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG4899-PA, isoform A - Tribolium castaneum
Length = 295
Score = 114 bits (274), Expect = 2e-24
Identities = 65/195 (33%), Positives = 98/195 (50%), Gaps = 1/195 (0%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206
KV ITG + GIG +V +L E K++A++ + G+ LNS YG NK F+ D
Sbjct: 52 KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
V + N V++E G ID+VIN A + + ++K I N+ I TL+A +M
Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169
Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
K G GG ++N S + + P A+ ++ S G +F TGVRV+T+C
Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229
Query: 567 FGATDTALLTRRETR 611
G T+T + E R
Sbjct: 230 PGITNTNFIKDAEKR 244
>UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 268
Score = 105 bits (251), Expect = 1e-21
Identities = 62/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIA----EEAGKSLQVELNSKYG-NKTK 191
+KV +TG GIG +V+ L G K +AI D+ EE +L+ +L ++ +
Sbjct: 5 NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALK-QLEQEFAAQRFS 63
Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371
+Y DVT+ + F+ + V G +D+++NNA + + + VN T++I T+
Sbjct: 64 YYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMH 121
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
AIE MG + GGKGG ++ + S+ AL +P+Y ATK A+ F ++ +K GVR
Sbjct: 122 AIERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVR 179
Query: 552 VLTVCFGATDTAL 590
++ +C G T T +
Sbjct: 180 IVCLCPGMTKTKM 192
>UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium
castaneum|Rep: PREDICTED: similar to
15-hydroxyprostaglandin dehydrogenase - Tribolium
castaneum
Length = 255
Score = 102 bits (245), Expect = 6e-21
Identities = 60/192 (31%), Positives = 103/192 (53%), Gaps = 1/192 (0%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E K KV +TG A+GIG ++VR LL G+K ++++DI+E EL ++ F
Sbjct: 3 ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFI 53
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
++DVT ++ + V +D+V+NNA ++ D I +K+ I++N+ A+I T A+
Sbjct: 54 KTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLAL 111
Query: 378 EI-MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
+ K+ G ++N +SV L PIY +K V+ +G P + + VR+
Sbjct: 112 RTYLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRI 171
Query: 555 LTVCFGATDTAL 590
+T+C G DT +
Sbjct: 172 VTICPGLVDTPM 183
>UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep:
CG18814-PA - Drosophila melanogaster (Fruit fly)
Length = 285
Score = 99.5 bits (237), Expect = 6e-20
Identities = 64/205 (31%), Positives = 107/205 (52%), Gaps = 17/205 (8%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206
K V G GIG+ V+ LL + +K +AI D+ + L E ++ + FY+ D
Sbjct: 6 KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 347
+T + A ++ G DVV+N + L++D +I I +E+ ++
Sbjct: 64 ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123
Query: 348 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518
+I STL A+E M K GG+GG ++N+SSVA L + +M IY +K+ V F+ +
Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183
Query: 519 RPEHFSKTGVRVLTVCFGATDTALL 593
P H++ +GV +T+C G T+T +L
Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGIL 208
>UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4;
Proteobacteria|Rep: Putative dehydrogenase - Azoarcus
sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 267
Score = 98.3 bits (234), Expect = 1e-19
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 7/199 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M KV +++GAA+GIG ++ R+ EG + + D+ E G+++ + + G +
Sbjct: 1 MKQNLSGKVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRA 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 350
F DV+DE + L V+E GG+D+++NNA L + + K + VNV
Sbjct: 59 LFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAG 118
Query: 351 LITSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
+I AI M S GKGG++IN+SSVA L + + +Y ATK AV S
Sbjct: 119 VILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVEC 178
Query: 528 HFSKTGVRVLTVCFGATDT 584
G+RV ++ G DT
Sbjct: 179 GRLGYGIRVNSIHPGLVDT 197
>UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23;
Schizophora|Rep: Alcohol dehydrogenase - Bactrocera
oleae (Olive fruit fly)
Length = 258
Score = 96.3 bits (229), Expect = 5e-19
Identities = 60/196 (30%), Positives = 103/196 (52%), Gaps = 2/196 (1%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSKYGNKTKFYRSD 206
VVF+ G IG + ++ + V + D+ E A K+LQ +N K K + + D
Sbjct: 8 VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
+T++ V+ + IDV++N A ++ D + + +N+ LI +TL+AI +M
Sbjct: 64 ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121
Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
K+ G+GG ++N++SV L + IY A+K V+ FS I P +++ TG+ V T C
Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181
Query: 567 FGATDTALLTRRETRH 614
G T+T L T++
Sbjct: 182 PGLTETPLKNNIATKY 197
>UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma
infestans|Rep: Oxidoreductase - Triatoma infestans
(Assassin bug)
Length = 252
Score = 95.9 bits (228), Expect = 7e-19
Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 8/196 (4%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
WKD+V +TGA+ GIGE++ R L + G+K +A L + + LQ + N+ G+ K Y+
Sbjct: 4 WKDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYK 61
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITS 362
DVT+E + ++V + G I V++NNA L M D S G ++ E NV L+T
Sbjct: 62 CDVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTF 121
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
T +EIM KH+ G +IN++S+A + M Y A+K AV + +
Sbjct: 122 TQHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAM 180
Query: 537 KTGVRVLTVCFGATDT 584
K+ +RV ++ G +T
Sbjct: 181 KSKIRVTSISPGLVNT 196
>UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR;
n=10; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
JLS)
Length = 282
Score = 93.9 bits (223), Expect = 3e-18
Identities = 52/173 (30%), Positives = 94/173 (54%), Gaps = 8/173 (4%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E + +V +TG A+GIG V + EG K + I D+ +E G++L + G F+
Sbjct: 8 ELQGRVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFH 62
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTAL 353
+DV D+E +++ V+ G +DV++NNA L N+ + + + + VN+ ++
Sbjct: 63 HTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSV 122
Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 512
+ T A M +H GG ++IN+SS+ + +P+Y A+K+A+L F+ C
Sbjct: 123 MAGTRDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKC 172
>UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 266
Score = 93.5 bits (222), Expect = 4e-18
Identities = 61/194 (31%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
V +TG GIG ++ + LLD K + +LDI E+ G L+ Y ++ F + DV
Sbjct: 7 VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 374
T + G +D++ NNA + ND + G +K I++NV +I TL
Sbjct: 66 TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125
Query: 375 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
++ MG G GGT++NV+S+A L + P+Y A+K AV+ + + ++ VR
Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183
Query: 552 VLTVCFGATDTALL 593
V +C TDTA++
Sbjct: 184 VNCICPSFTDTAMV 197
>UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=7; Alphaproteobacteria|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 261
Score = 92.7 bits (220), Expect = 7e-18
Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 7/169 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YRSD 206
K FITG A G+G + R+L EG K +A+ DI +++ E+N+ +G T F + D
Sbjct: 11 KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 368
VT E+ ++ +L GG+ V++NNA + D G++KK + VNV ++
Sbjct: 70 VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515
A+ M H + G++IN+SS+A L + P Y A+K+AV S I
Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAVWLLSKNI 175
>UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1;
Planctomyces maris DSM 8797|Rep: Probable putative
oxidoreductase - Planctomyces maris DSM 8797
Length = 270
Score = 91.5 bits (217), Expect = 2e-17
Identities = 60/194 (30%), Positives = 95/194 (48%), Gaps = 3/194 (1%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
++D+VV +TG + GIGE R+ EG H+AIL AG+ L ELN K F +
Sbjct: 18 FQDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQ 76
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLK 371
DV + E ++ VV++ G +D +INNA + ++ + + +IE + ST
Sbjct: 77 CDVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFA 136
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
+ H GT+IN+SS+ A+ H Y +TK A + F+ + + GVR
Sbjct: 137 GAKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVR 194
Query: 552 VLTVCFGATDTALL 593
V + DT L+
Sbjct: 195 VNAILPSNIDTPLM 208
>UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima
TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to
tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase -
Yarrowia lipolytica (Candida lipolytica)
Length = 291
Score = 91.1 bits (216), Expect = 2e-17
Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 8/195 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG A G+G S+ L G+K IAILD+ ++ G +L+ YG + +FY++DV
Sbjct: 46 KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
DEE I++ VV + G +DVV+N+A + + +++ I++N+ T
Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSKTG 545
A M K G GGTV+ ++S++ + P Y A+K+AV S + ++
Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221
Query: 546 VRVLTVCFGATDTAL 590
+R ++ G DTAL
Sbjct: 222 IRCNSISPGYMDTAL 236
>UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:
Dehydrogenase - Bradyrhizobium japonicum
Length = 271
Score = 89.8 bits (213), Expect = 5e-17
Identities = 59/203 (29%), Positives = 106/203 (52%), Gaps = 7/203 (3%)
Frame = +3
Query: 3 LNMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
+NM+ + + KV +TG A+GIGE++V + EG IA D+ E G L + +K G
Sbjct: 1 MNMAGQVEGKVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPELAKRI-TKAGG 58
Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVN 341
K F DV+ EE ++ I+ + + G +D++++NA ++++ ++G ++K +N
Sbjct: 59 KAIFLEQDVSSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAIN 118
Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
+ + S + +M K GG+++ +SS+A L + + Y ATK V F+ I
Sbjct: 119 LDGVFLSVKHCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAM 175
Query: 522 PEHFSKTGVRVLTVCFGATDTAL 590
G+RV +V G DT +
Sbjct: 176 ECAAVGDGIRVNSVHPGIIDTPI 198
>UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family
protein; n=4; cellular organisms|Rep: Short-chain
dehydrogenase/reductase family protein - Gramella
forsetii (strain KT0803)
Length = 249
Score = 89.8 bits (213), Expect = 5e-17
Identities = 64/195 (32%), Positives = 98/195 (50%), Gaps = 6/195 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K K + ITGA++GIGE+ L EGV ++ + EE K L+ +++ + G K
Sbjct: 4 KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 365
DVT +E F +++ +E G ID +INNA LM N + K ++VN+ ++
Sbjct: 63 DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ M + K G +IN+SS AA +Y ATKSAV FS + R E K
Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178
Query: 546 VRVLTVCFGATDTAL 590
+ + ++ G DT L
Sbjct: 179 INITSIEPGFVDTEL 193
>UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae
str. PEST
Length = 191
Score = 89.4 bits (212), Expect = 6e-17
Identities = 58/195 (29%), Positives = 99/195 (50%), Gaps = 1/195 (0%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS + VVF G G+G ++ + LL +GVK + I+D+ E +L S
Sbjct: 1 MSLAGQSAVVF--GGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALI 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
D+++ +L + E G ID+++N+A ++ + K I T +I S
Sbjct: 59 LCKICDISNRAALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSC 113
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
L A+ +M + GGKGG ++NV+S A L +P Y A+K ++ F+ +G +S+TG
Sbjct: 114 LIALNLMSRAKGGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETG 173
Query: 546 VRVLTVCFGATDTAL 590
V+ + +C G T T +
Sbjct: 174 VKFIIICPGGTRTRM 188
>UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=16; Bacillaceae|Rep:
Oxidoreductase, short-chain dehydrogenase/reductase
family - Bacillus anthracis
Length = 264
Score = 87.8 bits (208), Expect = 2e-16
Identities = 63/198 (31%), Positives = 101/198 (51%), Gaps = 6/198 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+ ++KV+ ITGA++GIGE V + ++G + ++ EE K+L ++ Y
Sbjct: 1 MTGRLQNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPC 59
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
+Y DV++E + + V+QE G ID+++NNA + S+ K +VNV
Sbjct: 60 YYYVLDVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFG 119
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
L+ T + M K + G +IN++S+A + Y ATK AVL F+N + R E
Sbjct: 120 LVACTKAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME- 174
Query: 531 FSKTGVRVLTVCFGATDT 584
S T V V + G DT
Sbjct: 175 LSSTNVFVTAINPGPIDT 192
>UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain
dehydrogenase/reductase SDR - Flavobacterium johnsoniae
UW101
Length = 269
Score = 87.4 bits (207), Expect = 2e-16
Identities = 61/190 (32%), Positives = 100/190 (52%), Gaps = 6/190 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY-GNKTKFYR 200
KDK + ITG TGIG+++ +L+ G + + I E+ K+ ++ ++ G++
Sbjct: 30 KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 365
+DVT +E IL E GGID++INNAAL N+S YK I+ N+T +
Sbjct: 89 ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+A M + K G +IN+ S++A ++ IY ATKSA+ FS + + + G
Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203
Query: 546 VRVLTVCFGA 575
++V + GA
Sbjct: 204 IKVSLIEPGA 213
>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
Oxidoreductase - Oceanobacillus iheyensis
Length = 244
Score = 87.0 bits (206), Expect = 3e-16
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 6/196 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+DKV ITG +GIG + ++ EG K I ++D+ EE G S++ EL S+ G++ F ++
Sbjct: 4 QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
DVT+EE I + G +D++ NNA + + ++K +EV++ +
Sbjct: 62 DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
AI+ K G ++N +S+ S Y A K+ V+ + +G ++
Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176
Query: 546 VRVLTVCFGATDTALL 593
+RV +C G DTA+L
Sbjct: 177 IRVNALCPGFIDTAIL 192
>UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=3; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus
furiosus
Length = 260
Score = 87.0 bits (206), Expect = 3e-16
Identities = 58/202 (28%), Positives = 103/202 (50%), Gaps = 6/202 (2%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K+KV +TG GIG ++ ++ + G K + + +I EEAG + L + G F ++
Sbjct: 7 KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 365
DV DEE ++ V+ GG+D+++NNAA+M+ ++ +++ I VN+T +
Sbjct: 65 DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A E M K GG +IN++S AL Y A+K +L ++ + +K
Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179
Query: 546 VRVLTVCFGATDTALLTRRETR 611
+RV+ V G +T+ + + R
Sbjct: 180 IRVVAVSPGWIETSRWKKSKLR 201
>UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
dehydrogenase/reductase SDR - Methanospirillum hungatei
(strain JF-1 / DSM 864)
Length = 249
Score = 87.0 bits (206), Expect = 3e-16
Identities = 58/204 (28%), Positives = 105/204 (51%), Gaps = 8/204 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
++KV+ +TG + GIG+++ DEG K + + EE+ K++ E++ K G+ ++
Sbjct: 6 ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 365
DV +E+ ++N + E G +D+++NNA +M +++ + K E N +
Sbjct: 65 DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A ++M KH K G +IN+SSV + S +Y ATKS ++ F+ + + G
Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179
Query: 546 VRVLTVCFGATDTALL--TRRETR 611
+ V + G DT L + ETR
Sbjct: 180 ITVNAIAPGFIDTDLTHDVKDETR 203
>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
B14905
Length = 252
Score = 86.6 bits (205), Expect = 4e-16
Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 7/198 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E +K+ +TGA +GIG + L G K + I+D +E G+ ++L + G + F
Sbjct: 2 EHLNKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFV 59
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 356
++DV+ E +NA V+ G IDV NNA ++ + Y + + +NV +
Sbjct: 60 QADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVF 119
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
I++M G G++IN +S A + H M +Y A+K AV+ + +
Sbjct: 120 LGLKHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYV 174
Query: 537 KTGVRVLTVCFGATDTAL 590
K G+R+ +C G +TAL
Sbjct: 175 KKGIRINAICPGGVETAL 192
>UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=2; Actinomycetales|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Mycobacterium avium (strain 104)
Length = 250
Score = 86.2 bits (204), Expect = 6e-16
Identities = 56/189 (29%), Positives = 101/189 (53%), Gaps = 4/189 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGAA+GIGE+ + L ++G K + + DI E+ G+ + E+ ++ G + F R+D+
Sbjct: 6 KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 380
+ EE +++ V GG+ + NNAA+ + +++ + +V VT + + T +
Sbjct: 64 SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123
Query: 381 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
H G GG ++N +S AAL + M Y ATK ++ + G +++ G+RV
Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181
Query: 558 TVCFGATDT 584
V G+ T
Sbjct: 182 AVAPGSIKT 190
>UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1;
Apis mellifera|Rep: Short-chain dehydrogenase/reductase
- Apis mellifera (Honeybee)
Length = 246
Score = 85.8 bits (203), Expect = 8e-16
Identities = 53/194 (27%), Positives = 102/194 (52%), Gaps = 9/194 (4%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M W D+V +TGA +GIG+ ++ L+ +G+K I I ++ K+L EL SK G K
Sbjct: 1 MEQNWIDEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KL 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
+ D++++ L ++ V + G ID++INNA L ND + +KK ++N+
Sbjct: 59 VPLQCDLSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLG 118
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCIGR 521
L + +++M K G G ++N++ + L + P Y A+K A+ ++C+
Sbjct: 119 LTCMIQEVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRS 177
Query: 522 PEHFSKTGVRVLTV 563
++ ++V+++
Sbjct: 178 ELAQCESNIKVISI 191
>UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase
bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis
oxidoreductase bacC - Bacillus subtilis
Length = 253
Score = 85.4 bits (202), Expect = 1e-15
Identities = 61/194 (31%), Positives = 101/194 (52%), Gaps = 6/194 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
DK V ITG A+GIG + V+ L + ++ + DI E G+++ + N+ ++ F ++D
Sbjct: 5 DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 368
+TDE + + V GG+DV+INNA + + + K ++VN+T + +
Sbjct: 61 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
A++ M + GK G +IN SV L +P Y A+K VLQ + + ++K +
Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175
Query: 549 RVLTVCFGATDTAL 590
RV VC G DT L
Sbjct: 176 RVNCVCPGIIDTPL 189
>UniRef50_Q2W431 Cluster: Dehydrogenase with different
specificities; n=2; Magnetospirillum|Rep: Dehydrogenase
with different specificities - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 248
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 6/198 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
+++DKV ITG A+GIG V+ + + G + I DI EAG+ EL +K G K +F
Sbjct: 2 KFEDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFV 59
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 359
R DVTD+ + + VV +G +D++ N A +++ K + +N+T I
Sbjct: 60 RLDVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIE 119
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
+M + GK ++NV+S A S +Y A K ++ FS + R ++
Sbjct: 120 LIRAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGAR 174
Query: 540 TGVRVLTVCFGATDTALL 593
+ V +C G TDT LL
Sbjct: 175 FNINVNAICPGPTDTPLL 192
>UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Sphingomonadales|Rep: Short-chain
dehydrogenase/reductase SDR - Sphingopyxis alaskensis
(Sphingomonas alaskensis)
Length = 285
Score = 84.6 bits (200), Expect = 2e-15
Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGAA+GIG++ V L EG H+ DI E G++L N + F R DV
Sbjct: 6 KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 380
T +++A + GGID+V NNAA D I + + + + ++ S I
Sbjct: 61 TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120
Query: 381 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
H G KG +++N +SVAAL + Y K+ VL + ++ G+RV
Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178
Query: 558 TVCFGATDT 584
+C G +T
Sbjct: 179 AICPGFINT 187
>UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Herpetosiphon aurantiacus ATCC 23779
Length = 247
Score = 84.6 bits (200), Expect = 2e-15
Identities = 57/195 (29%), Positives = 102/195 (52%), Gaps = 7/195 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG A GIG + ++L +G + I DI E+ G + ++ G + F DV
Sbjct: 5 KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 368
+ E ++ + +QGG+D++INNA + ++ ++ +++++T +
Sbjct: 63 SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
A + M +GGKGG ++NV+S+A + S + Y K+ V+Q S G E + G+
Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177
Query: 549 RVLTVCFGATDTALL 593
R+ VC G T+TA+L
Sbjct: 178 RINAVCPGWTETAIL 192
>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
reductase - Leptospira interrogans
Length = 254
Score = 84.2 bits (199), Expect = 2e-15
Identities = 57/192 (29%), Positives = 96/192 (50%), Gaps = 6/192 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K K +TGAA GIG+S L G ++ I D+ EE+ K+ E++ + G K +
Sbjct: 5 KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 365
+V+D + + A V E G +D+++NNA + D++ + K I VN+T T
Sbjct: 64 NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
AI+ M K+ GG++IN+SS+A + + Y A+K+ V+ F+ + K
Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181
Query: 546 VRVLTVCFGATD 581
+ F AT+
Sbjct: 182 CNAIAPGFIATE 193
>UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep:
Blr4846 protein - Bradyrhizobium japonicum
Length = 255
Score = 83.4 bits (197), Expect = 4e-15
Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 5/170 (2%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
D+VV ITG A+GIG + VR +G + +A LDI E AG SL E+ + G F R D
Sbjct: 11 DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 377
+ D + + V G V++NNAA ND + + +I LK +
Sbjct: 70 LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127
Query: 378 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
++ + GG++IN+SS+A + +P+Y A K+A++ F+N + R
Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177
>UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485;
Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 256
Score = 83.4 bits (197), Expect = 4e-15
Identities = 57/189 (30%), Positives = 93/189 (49%), Gaps = 2/189 (1%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVE-LNSKYGNKTKFYRSDV 209
V+F+ G GIG + LL +K++ ILD E +++ +N K FY DV
Sbjct: 10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66
Query: 210 TDE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
T +L + + +DV+IN A +++D ++ I VN T L+ +T ++
Sbjct: 67 TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124
Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
K GG GG + N+ SV + +P+Y TK+AV+ F++ + + TGV TV
Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182
Query: 567 FGATDTALL 593
G T T L+
Sbjct: 183 PGITRTTLV 191
>UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1;
Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP]
reductase - Psychroflexus torquis ATCC 700755
Length = 251
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/193 (32%), Positives = 103/193 (53%), Gaps = 2/193 (1%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M + K K ITG + GIG+S+ L +EGV +IAI +EA + + EL K G K
Sbjct: 1 MDLQLKGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKV 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITS 362
DV D E F L AV E G +D+++NNA+ M D ++ ++++++ A + +
Sbjct: 59 FTQTCDVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRA 118
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
T K + M + SG G ++ +SSV+ L +S P Y A K+A++ +S + +
Sbjct: 119 TKKVVPWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQ 172
Query: 543 GVRVLTVCFGATD 581
+RV T+ GA +
Sbjct: 173 HIRVNTIAPGAIE 185
>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caulobacter sp. K31|Rep: Short-chain
dehydrogenase/reductase SDR - Caulobacter sp. K31
Length = 277
Score = 82.6 bits (195), Expect = 7e-15
Identities = 56/193 (29%), Positives = 100/193 (51%), Gaps = 6/193 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K+ +TGAA G+G ++ + L+EG + + D++EE EL + + R DV
Sbjct: 9 KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
D E F +++A V E G +D+++NNA + S+ + + VNV+++
Sbjct: 64 GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
AI M + GG +INV+S+A L + Y A+K+AV+ F+ + +H + +R
Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178
Query: 552 VLTVCFGATDTAL 590
V +C G+ +T +
Sbjct: 179 VNAICPGSVETEM 191
>UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep:
Fat body protein 2 - Drosophila melanogaster (Fruit fly)
Length = 256
Score = 82.6 bits (195), Expect = 7e-15
Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 2/194 (1%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTK 191
+W K V G+ +GIG ++ L+ + +K + I+ E E K LQ +N K
Sbjct: 3 DWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVV 59
Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371
F + ++ ++ + + Q G IDV+IN ++ D + + +N+T +I ST+
Sbjct: 60 FMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMM 117
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A+ M K G GG V+N+SSV L + +Y A +L F+ +G + KTGV
Sbjct: 118 AMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVM 177
Query: 552 VLTVCFGATDTALL 593
+ +C G T++ ++
Sbjct: 178 FMAMCPGLTNSEMI 191
>UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier
protein) reductase - Leptospira interrogans
Length = 256
Score = 82.2 bits (194), Expect = 9e-15
Identities = 61/202 (30%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M + KDKV +TG +TGIG++VV+ + +GVK + E GK L+ E+ ++ G
Sbjct: 1 MENIMKDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDV 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVT 347
F DVT E +++A +++ G +D INNA +M N + ++ K + VN+
Sbjct: 59 YFVVCDVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLK 118
Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
S I M K GG V+NVSS++ + + Y A K V+ +
Sbjct: 119 GTWLSMKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL-- 173
Query: 528 HFSKTGVRVLTVCFGATDTALL 593
++K +R+ +C GA T +L
Sbjct: 174 EYAKKNIRINAICPGAVKTEIL 195
>UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3;
Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp.
SG-1
Length = 279
Score = 81.8 bits (193), Expect = 1e-14
Identities = 54/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
++K ITGA +G+G+S L EG+ IA++DI EE G VE+ + G F ++
Sbjct: 31 ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 362
DV+ E ++ V+E G +D NNA + +N I ++ + +N+ +
Sbjct: 89 DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
E+M K+ GG+++N +S A + + Y ATK ++ + + ++K
Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203
Query: 543 GVRVLTVCFGATDTALL 593
G+RV + G T+T ++
Sbjct: 204 GLRVNAIAPGPTETPMV 220
>UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member
11 precursor; n=30; Euteleostomi|Rep:
Dehydrogenase/reductase SDR family member 11 precursor -
Homo sapiens (Human)
Length = 260
Score = 81.8 bits (193), Expect = 1e-14
Identities = 59/199 (29%), Positives = 99/199 (49%), Gaps = 11/199 (5%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSK-YGNKTK 191
W+D++ +TGA+ GIG +V R L+ +G+K ++ A G + L E S Y
Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65
Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 353
YR D+++EE L + +A+ + G+D+ INNA L++ S +K VNV AL
Sbjct: 66 PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125
Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 527
T +A + M K G +IN++S++ + V Y ATK AV + + +
Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184
Query: 528 HFSKTGVRVLTVCFGATDT 584
++T +R + G +T
Sbjct: 185 REAQTHIRATCISPGVVET 203
>UniRef50_Q28GY1 Cluster: Novel protein containing short chain
dehydrogenase domain; n=4; Deuterostomia|Rep: Novel
protein containing short chain dehydrogenase domain -
Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 255
Score = 81.4 bits (192), Expect = 2e-14
Identities = 61/202 (30%), Positives = 97/202 (48%), Gaps = 9/202 (4%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-Y 197
WK +V +TGA+ GIG +V R+L+ G+K + ++ K L E S T F Y
Sbjct: 4 WKGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKIEK-LAAECQSAGYPGTLFPY 62
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 359
+ D+++EE L + +A+ G+DV INNA L++ ++ I+VNV AL
Sbjct: 63 KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSI 122
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCIGRPEHF 533
T +A + M K G +IN++SV +F ATK V + I +
Sbjct: 123 CTREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELRE 181
Query: 534 SKTGVRVLTVCFGATDTALLTR 599
K+ +RV ++ G +T R
Sbjct: 182 LKSHIRVTSISPGLVETEFAYR 203
>UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 258
Score = 81.4 bits (192), Expect = 2e-14
Identities = 55/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG A G+G + R+ + EG + I D+ + G++L EL G+ +F R DV
Sbjct: 7 KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 383
DE +++ + +A +++ G IDV++NNAA++ + K+ E V+ + T I
Sbjct: 62 ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121
Query: 384 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
+ H K G+++N+SSV L + + Y ++K V + GVRV +
Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179
Query: 561 VCFGATDTAL 590
+ G +TA+
Sbjct: 180 IHPGGVNTAM 189
>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
TM_0325 - Thermotoga maritima
Length = 251
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/200 (32%), Positives = 97/200 (48%), Gaps = 6/200 (3%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
++ KVV ITGA +GIG+ + + G K +AI DI+EE GK VEL G + F
Sbjct: 3 FQGKVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIF 60
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITS 362
DV + I+ V+ G +D+++NNA ++ S + K + VNV
Sbjct: 61 GDVAKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ A+E M K GG ++NVSS A L +Y +K+A+L + + +
Sbjct: 119 SKYAVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDY 173
Query: 543 GVRVLTVCFGATDTALLTRR 602
G+RV VC G T + L R
Sbjct: 174 GIRVNAVCPGTTQSEGLMAR 193
>UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep:
All3753 protein - Anabaena sp. (strain PCC 7120)
Length = 263
Score = 81.0 bits (191), Expect = 2e-14
Identities = 63/205 (30%), Positives = 100/205 (48%), Gaps = 6/205 (2%)
Frame = +3
Query: 3 LNMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
+N +H+ + ITGAA+GIG +V I + ++ ++D A+E + + +E K+G
Sbjct: 1 MNTTHK---QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGI 56
Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNV 344
K D++ I V Q +DV++NNA L ND+ + + ++VNV
Sbjct: 57 SVKPIVRDLSKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNV 116
Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
T ++ M + GK ++NVSS AA +M +YFATK+ VL FS +
Sbjct: 117 VCTTHLTKLFLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA-- 171
Query: 525 EHFSKTGVRVLTVCFGATDTALLTR 599
TGV V +C G T +A R
Sbjct: 172 NELDGTGVTVTVLCPGTTQSAFHQR 196
>UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces
avermitilis|Rep: Putative dehydrogenase - Streptomyces
avermitilis
Length = 258
Score = 81.0 bits (191), Expect = 2e-14
Identities = 58/193 (30%), Positives = 102/193 (52%), Gaps = 6/193 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+VV I+GAA G GE R+ ++EG K + + D+ ++ G++L E+ ++Y DV
Sbjct: 7 RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 371
E+ + + G ID ++NNA ++ ND +G +++ ++VN + +K
Sbjct: 60 GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
+ + +G GGT++N +S A LT + Y ATK A++ + + E +K +R
Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174
Query: 552 VLTVCFGATDTAL 590
V VC GA DTA+
Sbjct: 175 VNAVCPGAIDTAM 187
>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Hyphomonas neptunium
(strain ATCC 15444)
Length = 262
Score = 81.0 bits (191), Expect = 2e-14
Identities = 53/192 (27%), Positives = 93/192 (48%), Gaps = 2/192 (1%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
+++KV ITGAA+GIG + R+L EG H+ + D+ + GKS+ +L G +
Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVK 60
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 374
DV+ ++ A V+ G ID++ NNA + S+ I E + + S A
Sbjct: 61 CDVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYA 120
Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
H +G ++N +S++ L + Y A K AV+ ++ + +H + G+RV
Sbjct: 121 CHFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRV 177
Query: 555 LTVCFGATDTAL 590
+C G +T +
Sbjct: 178 NALCPGLVETPI 189
>UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=1; Tetrahymena
thermophila SB210|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Tetrahymena
thermophila SB210
Length = 843
Score = 81.0 bits (191), Expect = 2e-14
Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 6/198 (3%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
V +TGAA G G+ + + +I I DI E+ + E+ K G K FY+ DV+D
Sbjct: 577 VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635
Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 377
E+ + + +Q+ ID++INN + N S +KA VN A ++ K +
Sbjct: 636 EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+M + + G ++NVSSVA+L S M Y A+K+A+ F N + K +
Sbjct: 696 PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752
Query: 558 TVCFGATDTALLTRRETR 611
+C A +T +L ET+
Sbjct: 753 LICPYAVNTGVLQGLETK 770
>UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa
protein; n=44; Drosophiliti|Rep: Alcohol
dehydrogenase-related 31 kDa protein - Drosophila
melanogaster (Fruit fly)
Length = 272
Score = 81.0 bits (191), Expect = 2e-14
Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 1/174 (0%)
Frame = +3
Query: 60 GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT-DEEHFLGI 236
GI ++L+ + + +AIL E Q++ + K + F+ DVT E
Sbjct: 17 GIALETSKVLMTKNIAKLAILQSTENPQAIAQLQ-SIKPSTQIFFWTYDVTMAREDMKKY 75
Query: 237 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 416
+ V+ + IDV+IN A L +++ I N+T ++ + + M + GG GG
Sbjct: 76 FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133
Query: 417 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGAT 578
++NV+SV L S V Y A+K V+ F+ + P ++S+ GV V+ VC G T
Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCGPT 187
>UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 251
Score = 80.6 bits (190), Expect = 3e-14
Identities = 61/202 (30%), Positives = 97/202 (48%), Gaps = 6/202 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITG A G GE+ R + EG + + I D+ +EAG+ + EL G+ +F DV
Sbjct: 7 KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
T E + ++A + + G +D+++NNAA++ S+ Y+K I+VN
Sbjct: 62 TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A +G GG+++NVSS A + Y ++K AV + F + G+R
Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176
Query: 552 VLTVCFGATDTALLTRRETRHF 617
V +V G DT + E F
Sbjct: 177 VNSVHPGGIDTVMARPPEFADF 198
>UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Parvibaculum
lavamentivorans DS-1
Length = 268
Score = 80.6 bits (190), Expect = 3e-14
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 9/197 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGAA GIG + + L EG K + D E G+ + E+ + G T F+R DV
Sbjct: 7 KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 368
TDE + ++ ++ GG+ VV+NNA + + ++ ++ IEV++ ++
Sbjct: 65 TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124
Query: 369 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
I + K++ GG GG ++N+SS+ L Y A K V + +
Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184
Query: 543 GVRVLTVCFGATDTALL 593
+RV +V G DT ++
Sbjct: 185 NIRVNSVHPGYIDTPMV 201
>UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR;
n=6; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
Length = 260
Score = 80.2 bits (189), Expect = 4e-14
Identities = 57/196 (29%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+K + ITG A+GIG + ++L G K I I D+AE+ G +L + + + F + D
Sbjct: 14 NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 365
VT + V++ GG+DVVINNA + + +++ + + VNV +
Sbjct: 72 VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
AI + H GG VINV+S+A L + ++ Y A+K AV+ + +++
Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTK--SAAIEYARAN 186
Query: 546 VRVLTVCFGATDTALL 593
+R VC DT ++
Sbjct: 187 IRFNAVCPSFIDTPMV 202
>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Chloroflexus|Rep: Short-chain
dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
9485
Length = 256
Score = 80.2 bits (189), Expect = 4e-14
Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 6/198 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E++ KV +TG A GIG + L EG + I D + A + VE + +G +
Sbjct: 2 EFQGKVAIVTGGAQGIGRATALALAREGAA-VVIAD-RDAAATTALVEGINAWGGRALAV 59
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 359
+DV+DE I N V E GGID+++NNA + + ++ ++++ I VN+T +
Sbjct: 60 IADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF- 118
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
L + +M + GG ++NV+SV L Y A+K V+ + + +
Sbjct: 119 --LVSRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--AP 174
Query: 540 TGVRVLTVCFGATDTALL 593
G+RV VC G DT+LL
Sbjct: 175 DGIRVNCVCPGLIDTSLL 192
>UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Bacteria|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Pseudomonas putida (strain KT2440)
Length = 262
Score = 79.8 bits (188), Expect = 5e-14
Identities = 53/204 (25%), Positives = 97/204 (47%), Gaps = 7/204 (3%)
Frame = +3
Query: 3 LNMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
+ +++++ KVV +TGA +GIG + G +A+ DI+ + G VEL G
Sbjct: 1 MTVNYDFSGKVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGG 58
Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVN 341
+ F+ DV E +L VV GG+D+ NNA + + + + +++ I+VN
Sbjct: 59 EATFFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVN 118
Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
++++ I +M K GG ++N +S + L + + Y ATK V+ +
Sbjct: 119 LSSVFYCLKGEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA- 174
Query: 522 PEHFSKTGVRVLTVCFGATDTALL 593
++ +R+ VC G D+ L
Sbjct: 175 -IDYANQNIRINAVCPGPVDSPFL 197
>UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2;
Actinomycetales|Rep: Short chain dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 267
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/190 (30%), Positives = 93/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221
+TG A G+G + L D G + I D+ EE G++ + K G T F + DVTD+
Sbjct: 13 VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRATADSVG-KTGVDTGFVKLDVTDDG 70
Query: 222 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 383
++ + A V++ GG+D+++NNA + S+ + ++ EVN+ + +
Sbjct: 71 NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130
Query: 384 MGK-HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
M + G GG ++NVSSVAA + Y ATKSAV + + + GVRV
Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190
Query: 561 VCFGATDTAL 590
V G T +
Sbjct: 191 VYPGLVATEM 200
>UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Leeuwenhoekiella blandensis MED217
Length = 257
Score = 79.8 bits (188), Expect = 5e-14
Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 6/167 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K+KV +TG A+G+G+S ++L EG K I + DI EE GK + V+ + G + F +
Sbjct: 5 KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKV-VQQIKEDGGEAIFIKQ 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 365
DV E+ + ++ ++ G + ++ N+A + + D ++ +K I++N+ T
Sbjct: 63 DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 506
I+ G +GG++IN SS+ L +P Y A+K V F+
Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFT 167
>UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4;
Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella
melitensis
Length = 272
Score = 79.4 bits (187), Expect = 7e-14
Identities = 58/197 (29%), Positives = 95/197 (48%), Gaps = 6/197 (3%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
+KDKVV +TG A+GIGE+ R + EG K + I D ++ G+ L EL + + F +
Sbjct: 3 FKDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIK 59
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 362
+DV D ++ V+ G +D++ NA + D+ ++K I++N+T +
Sbjct: 60 TDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLC 119
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
AI+ M S G GG ++N S+ + + Y A K V + + +
Sbjct: 120 DKYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQ 174
Query: 543 GVRVLTVCFGATDTALL 593
+RV VC G DT LL
Sbjct: 175 NIRVNAVCPGYIDTPLL 191
>UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep:
CylG - Streptococcus agalactiae
Length = 240
Score = 79.4 bits (187), Expect = 7e-14
Identities = 53/201 (26%), Positives = 97/201 (48%), Gaps = 7/201 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG GIG ++ + L EG K IAI + + ++LQ EL K Y+ ++
Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
+D + ++ + +E GGID ++NNA ++ D + + I +N+ L+ +
Sbjct: 57 SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116
Query: 372 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
++IM K GK VIN+SS + + Y ATK A++ + + + F+ G+
Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171
Query: 549 RVLTVCFGATDTALLTRRETR 611
+ V G +T + + +
Sbjct: 172 TINCVSPGFIETDMTNELQNK 192
>UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein;
n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short
chain dehydrogenase family protein - Candidatus
Desulfococcus oleovorans Hxd3
Length = 273
Score = 79.4 bits (187), Expect = 7e-14
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 6/197 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
DKV +TG A+G+G +V +L G + I DI E+ + + + + G T + D
Sbjct: 6 DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
T +E +++ E G +D + NNA ++ + S + + ++VN ++T TL
Sbjct: 64 TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
A IM + G +IN +S A L V+ Y TK AV+ S + RPE +K GV
Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178
Query: 549 RVLTVCFGATDTALLTR 599
RV VC G T++ +
Sbjct: 179 RVSVVCPGYVSTSIFDK 195
>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
Gammaproteobacteria|Rep: Short chain dehydrogenase -
marine gamma proteobacterium HTCC2143
Length = 259
Score = 79.4 bits (187), Expect = 7e-14
Identities = 53/202 (26%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS + +V +TG A GIG + EG+ ++ + D+ ++ G+ + + GN
Sbjct: 1 MSTTFSGQVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI 59
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
F DVT E ++ G +D NNA + + G K E +++ +
Sbjct: 60 -FVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNV 117
Query: 369 KAIEIMGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
K + + KH + GGT++N SS+ L + M IY A+K AV+ +
Sbjct: 118 KGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN-- 175
Query: 534 SKTGVRVLTVCFGATDTALLTR 599
++ G+R+ VC G DT + R
Sbjct: 176 ARNGIRINAVCPGVIDTNMFNR 197
>UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9;
Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas
sp. (strain NCIMB 9872)
Length = 250
Score = 79.4 bits (187), Expect = 7e-14
Identities = 52/166 (31%), Positives = 84/166 (50%), Gaps = 6/166 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
DKVV +TG A G+G + +L EG + + D+ EE G E+ + G K F D
Sbjct: 6 DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
VT+E H+ G ++ ++ E +D ++NNA ++ + S + + E+NV ++ T
Sbjct: 64 VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 506
IE M K G ++NVSS+ L + Y A+K AV F+
Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166
>UniRef50_Q46PX5 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
NAD-dependent epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR - Ralstonia eutropha (strain
JMP134) (Alcaligenes eutrophus)
Length = 253
Score = 79.0 bits (186), Expect = 9e-14
Identities = 59/199 (29%), Positives = 98/199 (49%), Gaps = 7/199 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KDKV +TG A+GIGE+ VR+ +G + I D G+ L EL S+ +
Sbjct: 9 KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 362
DV+ E+ +++ V G +D+++ NA + + S + +++ I+VN+T + S
Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
AI M K G GG ++N++S+ Y A K V+ + +G H ++
Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181
Query: 543 GVRVLTVCFGATDTALLTR 599
G+RV VC G T L+ R
Sbjct: 182 GIRVNAVCPGFVATPLIER 200
>UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
dehydrogenase/reductase SDR - Solibacter usitatus
(strain Ellin6076)
Length = 275
Score = 79.0 bits (186), Expect = 9e-14
Identities = 59/196 (30%), Positives = 97/196 (49%), Gaps = 6/196 (3%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
++ KV F+TG +G+G ++ L G IA+ DI EA + + + G K+ +
Sbjct: 4 FQGKVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMK 61
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITS 362
DV+ E +++VV G +D + NNA ++ +G+ + + I+VN+ ++
Sbjct: 62 LDVSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYG 121
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
T A M + G ++N++SV L Y ATK AV+ S + RPE SK
Sbjct: 122 TTAAYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKL 176
Query: 543 GVRVLTVCFGATDTAL 590
GVR+ VC G +T L
Sbjct: 177 GVRITVVCPGTMNTGL 192
>UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=4; Sphingomonas|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Pseudomonas paucimobilis (Sphingomonas paucimobilis)
Length = 250
Score = 79.0 bits (186), Expect = 9e-14
Identities = 63/200 (31%), Positives = 97/200 (48%), Gaps = 6/200 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M++ KV ITG A+G+G + + +EG K + I D+ EE K + E+ + G
Sbjct: 1 MANRLAGKVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDA 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 350
F R DVTD + + A V GG+ + N A +++ +SI + K + VN TA
Sbjct: 59 LFIRLDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTA 118
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+ AI + K SG G++IN+SS+ + + Y ATK+AV S
Sbjct: 119 IFLGIKAAIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--E 173
Query: 531 FSKTGVRVLTVCFGATDTAL 590
F GVRV T+ G +T +
Sbjct: 174 FVDRGVRVNTIVPGGMNTPI 193
>UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4;
Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase
- Comamonas testosteroni (Pseudomonas testosteroni)
Length = 254
Score = 79.0 bits (186), Expect = 9e-14
Identities = 51/168 (30%), Positives = 92/168 (54%), Gaps = 6/168 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M++ + KV +TG A+G+G VV++LL EG K +A DI E AG+ L EL G ++
Sbjct: 1 MTNRLQGKVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERS 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
F R DV+ E + ++ AV + G ++V++NNA ++ + + + +++N +
Sbjct: 56 MFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTES 115
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 494
+ + I M + GG++IN++SV++ Y A+K+AV
Sbjct: 116 VFIGCQQGIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159
>UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular
organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus
iheyensis
Length = 256
Score = 78.6 bits (185), Expect = 1e-13
Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 7/197 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+DKV +TGAA G+G++ IL E + I D EE G+ + VE + G + F +
Sbjct: 7 EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEV-VEEVKQAGGQAAFIKV 64
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 362
D++D ++ V + G +D+ +NNAAL D + K I V++T T+
Sbjct: 65 DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
E+ G GG+++N+SSV+ Y A K V+ + + E+
Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180
Query: 543 GVRVLTVCFGATDTALL 593
+RV TV GA DT +L
Sbjct: 181 NIRVNTVAPGAIDTPML 197
>UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR)
family protein; n=1; Thermobifida fusca YX|Rep:
Short-chain dehydrogenase/reductase (SDR) family protein
- Thermobifida fusca (strain YX)
Length = 282
Score = 78.6 bits (185), Expect = 1e-13
Identities = 57/194 (29%), Positives = 94/194 (48%), Gaps = 5/194 (2%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+ + +V ITG A+GIGE+ VR EG + I DI EAG+ L EL G++
Sbjct: 1 MTQRLRGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRA 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
F R+DV++E +++ V G +D+++NNA +M ++G + I L
Sbjct: 56 VFVRTDVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNL 114
Query: 369 KAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
+ + KH+ + G +I+ SS A + IY A K ++ SN +
Sbjct: 115 RGVICGMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AEL 172
Query: 534 SKTGVRVLTVCFGA 575
+ G+RV T+ G+
Sbjct: 173 RQHGIRVNTIIPGS 186
>UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 595
Score = 78.6 bits (185), Expect = 1e-13
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 7/201 (3%)
Frame = +3
Query: 12 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKT 188
S + KV +TGA +GIG EG +A +D+A +L + L G +
Sbjct: 322 SGRFSGKVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQA 378
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTA 350
R DV + + V GG DVVINNA + ++ S +++ + VN+
Sbjct: 379 HAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWG 438
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+I + + M G GG ++N +S AA S +P Y TK+AVL S C+ R E
Sbjct: 439 VIHGSRLFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE- 494
Query: 531 FSKTGVRVLTVCFGATDTALL 593
++ G+ V VC G +T ++
Sbjct: 495 LAEQGIGVTAVCPGFAETGIM 515
>UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Mesorhizobium sp. BNC1|Rep: Short-chain
dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
BNC1)
Length = 257
Score = 78.6 bits (185), Expect = 1e-13
Identities = 59/196 (30%), Positives = 98/196 (50%), Gaps = 5/196 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206
KV +TGAA G+GE++ L +G + +A+LD+ +E G + + GN +YR+ D
Sbjct: 7 KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGN--AYYRNCD 63
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 377
+ D E ++ V G +DV++NNAA+ I + + E N+ + S++
Sbjct: 64 IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123
Query: 378 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
++ + GG VIN+SSV Y ATK A++ S + + + +RV
Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181
Query: 555 LTVCFGATDTALLTRR 602
TV GA D A +TR+
Sbjct: 182 NTVSPGAID-ATMTRQ 196
>UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase;
n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein
reductase - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 249
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/203 (28%), Positives = 101/203 (49%), Gaps = 8/203 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+ KDKV ITG GIG + + EG K + + + G++ +K+G+
Sbjct: 1 MTDRLKDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAV----AKFGDDV 56
Query: 189 K-FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNV 344
F + DV+ E + +++A + + G +D+++NNA + +N +I ++K I+VN+
Sbjct: 57 SLFVQQDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNL 116
Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
TA AI+ M K + G++INVSSVA L + P Y A+K ++
Sbjct: 117 TANFLGEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALN 175
Query: 525 EHFSKTGVRVLTVCFGATDTALL 593
+RV +V G DT+++
Sbjct: 176 LAQRGIDIRVNSVHPGWIDTSIV 198
>UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Oceanobacillus iheyensis
Length = 255
Score = 78.2 bits (184), Expect = 2e-13
Identities = 64/199 (32%), Positives = 98/199 (49%), Gaps = 13/199 (6%)
Frame = +3
Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221
+TG A+G+GE+ VR L ++G K +AI D+ +E G+ L EL G+ +++ DVTDE
Sbjct: 10 VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64
Query: 222 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 371
L+ V+++ GI V+N A A+ +IG + IE+N+
Sbjct: 65 SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124
Query: 372 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
A E M +S G+ G +IN +SVAA Y A+K V + I R S
Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182
Query: 543 GVRVLTVCFGATDTALLTR 599
G+RV+T+ G T L +
Sbjct: 183 GIRVMTIAPGLFLTPLFEK 201
>UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus
iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
Length = 257
Score = 78.2 bits (184), Expect = 2e-13
Identities = 60/204 (29%), Positives = 107/204 (52%), Gaps = 7/204 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
+++DKV+ +TGAA GIG+ VVR + + K + ++D+ E+A KS+Q EL N +
Sbjct: 3 KFQDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVV 60
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 356
++DV++EE+ ++ + + G ID +NNA + + I + +NV ++
Sbjct: 61 KADVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVL 120
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
+ +M K G+++N +SVA L S M +Y ++K AV+ N + E +
Sbjct: 121 FGLKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-A 175
Query: 537 KTGVRVLTVCFGATDTALLTRRET 608
VRV TV G +T ++ E+
Sbjct: 176 AFNVRVNTVNPGVINTQMMRNIES 199
>UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier
protein) reductase - Oceanobacillus iheyensis
Length = 253
Score = 78.2 bits (184), Expect = 2e-13
Identities = 50/194 (25%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KDKV +TGAA+G+G+++ + EG K + + D+ EE +S+ E+ S G T +
Sbjct: 4 KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 362
++ +E +++ V G +D+++NNA +M+ +++G + ++N ++ +
Sbjct: 62 NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
KAI I + + G ++N +S L +H Y A+K AV+ + G ++ +
Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176
Query: 543 GVRVLTVCFGATDT 584
G+R + G T
Sbjct: 177 GIRCNAIAPGGVAT 190
>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
dehydrogenase/reductase SDR - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 252
Score = 78.2 bits (184), Expect = 2e-13
Identities = 60/191 (31%), Positives = 90/191 (47%), Gaps = 6/191 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITG ATGIG + + EG + I DI EE G S VE G F R DV
Sbjct: 7 KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
+ EE ++ A +E G +DVV NA L+ S ++ + +N+TA T
Sbjct: 65 SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A +M +H +GG++I ++S L + Y A+K ++ + + + + +R
Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179
Query: 552 VLTVCFGATDT 584
V VC G DT
Sbjct: 180 VNCVCPGWVDT 190
>UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;
n=11; cellular organisms|Rep: Uncharacterized
oxidoreductase TM_0019 - Thermotoga maritima
Length = 256
Score = 78.2 bits (184), Expect = 2e-13
Identities = 54/200 (27%), Positives = 99/200 (49%), Gaps = 6/200 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG GIG ++ ++ + G+K + I +I EEAG + L + G F ++DV
Sbjct: 5 KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
DE ++ V+ GG+DV++NNAA+M+ + +++ I VN+T +
Sbjct: 63 ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
E M K GG +IN++S A Y A+K ++ ++ + S+ +R
Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177
Query: 552 VLTVCFGATDTALLTRRETR 611
V+++ G +T+ ++ R
Sbjct: 178 VVSISPGWIETSEWKKKSLR 197
>UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2;
Bacteria|Rep: Short-chain dehydrogenase -
Symbiobacterium thermophilum
Length = 254
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/196 (30%), Positives = 91/196 (46%), Gaps = 6/196 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITGAA G+G + + EG + + I D+ EE G++ Q G F R+DV
Sbjct: 7 KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
+ ++ V G +DV +NNAA D+ + E A+I LK + +
Sbjct: 65 SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123
Query: 390 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
K+ G GG++IN+SSV+ + P Y A K V+ + +S G+R
Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181
Query: 552 VLTVCFGATDTALLTR 599
V V GA DT +L +
Sbjct: 182 VNAVAPGAVDTPMLQK 197
>UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=3; Clostridium
perfringens|Rep: Oxidoreductase, short-chain
dehydrogenase/reductase family - Clostridium perfringens
(strain ATCC 13124 / NCTC 8237 / Type A)
Length = 272
Score = 77.8 bits (183), Expect = 2e-13
Identities = 57/197 (28%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
+ DKV+ ITGAA GIG++V EG K + + D EE K E+ N +F
Sbjct: 9 FSDKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLI 66
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALIT 359
D+ + E+ +++ +++ GG+D++INNA + S +++ ++ N+
Sbjct: 67 CDLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFH 126
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
+ I+ M K + KGG ++NVSSVA LT Y +K + + + +++
Sbjct: 127 CSHYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYAR 182
Query: 540 TGVRVLTVCFGATDTAL 590
G+RV V G TDT +
Sbjct: 183 YGIRVNAVNPGTTDTPM 199
>UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=4; Shewanella|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Shewanella sp.
(strain ANA-3)
Length = 292
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/200 (26%), Positives = 98/200 (49%), Gaps = 7/200 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GKSLQVELNSKYGNKTKFYR 200
K KV ITG+ +GIG + +L ++G H+ + + EA G+ L E +Y T F
Sbjct: 35 KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 362
+D+ D E ++A V+ G ID+++NNA + + I + I +N+++ +
Sbjct: 94 ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+A+ M + + G +IN++SV L S Y A K ++ + + ++
Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208
Query: 543 GVRVLTVCFGATDTALLTRR 602
G+ V +C G DT L+ ++
Sbjct: 209 GITVNAICPGWVDTPLINKQ 228
>UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;
n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase
SSP0419 - Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 234
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/198 (28%), Positives = 102/198 (51%), Gaps = 7/198 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKF 194
E +DKV +TGA++GIG S+ L ++GVK + D + A + +++ N + +T
Sbjct: 3 ELQDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSI 62
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALI 356
DVT +E ++ ++ G ID+++N+A LM S + ++ I+VN+ +
Sbjct: 63 V--DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTL 120
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
+ + M S G +IN++S++ + +Y A+K+AV + G + +
Sbjct: 121 YTINAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELA 175
Query: 537 KTGVRVLTVCFGATDTAL 590
KTGVRV ++ G DT L
Sbjct: 176 KTGVRVTSISPGMVDTPL 193
>UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep:
Lin2278 protein - Listeria innocua
Length = 253
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/197 (25%), Positives = 99/197 (50%), Gaps = 8/197 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGAA+G+G+ + + EG K + + D+ EA + + + G ++V
Sbjct: 7 KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 368
T ++ ++N + G +D+++NNA +M++ + ++ K +N T ++ +T
Sbjct: 65 TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124
Query: 369 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
KA+ I + KG G ++N++S L S Y A+K AV+ F+ +G ++
Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178
Query: 546 VRVLTVCFGATDTALLT 596
+R + GA +T + T
Sbjct: 179 IRCNAIAPGAVNTNIGT 195
>UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2;
Streptomyces|Rep: Putative dehydrogenase - Streptomyces
avermitilis
Length = 584
Score = 77.4 bits (182), Expect = 3e-13
Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 9/194 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206
++V +TGA +GIG + + G + +A+ AE A ++ E++ G + + D
Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 368
V+DE+ + V E G +DV++NNA + + + ++K ++VN+ +I
Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430
Query: 369 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ GK G+GG ++N +S AA S +P Y +K+AVL S C+ R E +
Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488
Query: 543 GVRVLTVCFGATDT 584
G+ V +C G T
Sbjct: 489 GIGVSAICPGFVHT 502
>UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyces
coelicolor|Rep: Putative dehydrogenase - Streptomyces
coelicolor
Length = 276
Score = 77.4 bits (182), Expect = 3e-13
Identities = 55/202 (27%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 15 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194
HE+ + +TGA+ G+GE+ R L G H+ ++ + +A +L E+ + + +
Sbjct: 2 HEYTNTTALVTGASKGLGEAYARELASRGA-HLVLVARSADALHALADEIRATHSVRVDV 60
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 356
+D++D +L+AV +D+++NNA + + + ++++VNVTAL+
Sbjct: 61 IAADLSDRRSPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRPLAPNLQSVDVNVTALV 120
Query: 357 TSTLKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
+ ++G +G G ++N++S AA Y ATK+ VL F+ + E
Sbjct: 121 ----GLVHLLGARMVERGRGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVA--EEV 174
Query: 534 SKTGVRVLTVCFGATDTALLTR 599
TGVRV+ GAT T R
Sbjct: 175 RGTGVRVMAAHPGATATGFFDR 196
>UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Comamonas testosteroni
KF-1
Length = 259
Score = 77.4 bits (182), Expect = 3e-13
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+ ITGA GIG + + EG + + AE ++ + L + G + +DV
Sbjct: 9 RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 371
+DE + VQ+ GG+D ++NNAA+ N S A E VN+ +
Sbjct: 69 SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A+ + + SG G+++NVSS A+T M +Y ATK+A L ++ + E + GVR
Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183
Query: 552 VLTVCFGATDT 584
VC G+T T
Sbjct: 184 ANAVCPGSTLT 194
>UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Chromobacterium violaceum
Length = 246
Score = 77.0 bits (181), Expect = 4e-13
Identities = 56/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K KV ITG+A+GIG++ + EG +A+ D+ +A K++ EL + G + Y+
Sbjct: 4 KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365
DVTD+ ++ + G IDV++NNA ++ D+ I + K I++N+ +
Sbjct: 62 DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
++ M + GG ++N SSV + + Y A K V+ F + K G
Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176
Query: 546 VRVLTVCFGATDTALL 593
+R VC G T +L
Sbjct: 177 IRANAVCPGFVATPIL 192
>UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 250
Score = 77.0 bits (181), Expect = 4e-13
Identities = 48/169 (28%), Positives = 89/169 (52%), Gaps = 7/169 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGAA GIG ++ + EG K + I DI + G+ + EL G + F+ +DV
Sbjct: 10 KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 368
+D +++ ++ GG+ V+ NNA + ++D + +++ + V++ ++ +
Sbjct: 64 SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515
A M H GG ++N++S A +T M Y A K+ V+QF+ C+
Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169
>UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Gammaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Pseudoalteromonas
atlantica (strain T6c / BAA-1087)
Length = 270
Score = 77.0 bits (181), Expect = 4e-13
Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 9/198 (4%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K KV+ ITG ATGIG +V + + + + +D+ EEA +L +L+++ G F
Sbjct: 26 KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 362
D T + ++++ G +DV+INN A L D G ++ + VN+ + +
Sbjct: 85 DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
AI +M + G +IN+SS+ L MP Y A KSA+ S + + +
Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198
Query: 543 GVRVLTVCFG--ATDTAL 590
G+RV T+ G ATD L
Sbjct: 199 GIRVNTILPGWVATDRQL 216
>UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member
11 precursor; n=7; Eukaryota|Rep:
Dehydrogenase/reductase SDR family member 11 precursor -
Gallus gallus (Chicken)
Length = 255
Score = 77.0 bits (181), Expect = 4e-13
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 8/196 (4%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
W +V +TGA+ GIG +V R L+ G+K + ++ K ++ Y Y+
Sbjct: 4 WTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYK 63
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362
D+++EE L + +A+ G+DV INNA L++ ++ I+VNV A+
Sbjct: 64 CDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSIC 123
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
T +A + M K G +IN++S+ ++ V+ Y ATK AV + + + +
Sbjct: 124 TREAYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREA 182
Query: 537 KTGVRVLTVCFGATDT 584
KT +R + G +T
Sbjct: 183 KTHIRATCISPGLVET 198
>UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase;
n=1; Burkholderia xenovorans LB400|Rep: Putative
short-chain type dehydrogenase - Burkholderia xenovorans
(strain LB400)
Length = 252
Score = 76.6 bits (180), Expect = 5e-13
Identities = 62/199 (31%), Positives = 92/199 (46%), Gaps = 6/199 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+ K + ITGA IG+ R + EG + + I DIAEEAG+++ EL G
Sbjct: 1 MAGRLSGKRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAA 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
F + DVT E ++ V+ GG+D + NA L G + N AL
Sbjct: 56 HFVQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNA 113
Query: 369 KAIEIMGKHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+A KH+ GK G++IN+SS+A + Y A+K AV+ F+ +
Sbjct: 114 RAHFFGAKHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--E 170
Query: 531 FSKTGVRVLTVCFGATDTA 587
+ +RV +C G DTA
Sbjct: 171 LAPDNIRVNAICPGWVDTA 189
>UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3;
Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase -
Eubacterium sp. (strain VPI 12708)
Length = 266
Score = 76.6 bits (180), Expect = 5e-13
Identities = 51/197 (25%), Positives = 101/197 (51%), Gaps = 10/197 (5%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
KDKV+ +T + GIG ++ + EG K ++ ++ E K+ E+N+ GN K+
Sbjct: 4 KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 353
+D T EE ++ ++ +++++G IDV++NN + N ++ K + +N+ ++
Sbjct: 61 NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120
Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
++ A++ M ++ GG++IN+SSV L Y +K+A+ + I H
Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175
Query: 534 SKTGVRVLTVCFGATDT 584
++ +R V G T T
Sbjct: 176 ARHNIRCNAVLPGMTAT 192
>UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;
Bacteria|Rep: Short-chain alcohol dehydrogenase -
Burkholderia dolosa AUO158
Length = 284
Score = 76.6 bits (180), Expect = 5e-13
Identities = 58/195 (29%), Positives = 100/195 (51%), Gaps = 7/195 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+KVV ITGA++GIGE+ ++L +G +A+ + + + E+ +K G + ++ D
Sbjct: 44 NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 368
VTD+E ++N VV + G +DV++NNA LM + + + K + I++N+ L+
Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A+ + K + G +N++SV L S +Y TK AV S + H
Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215
Query: 546 VRVLTVCFGATDTAL 590
+R + GA DT L
Sbjct: 216 IRTTVISPGAIDTEL 230
>UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=5; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Mycobacterium
sp. (strain KMS)
Length = 261
Score = 76.6 bits (180), Expect = 5e-13
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 8/201 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+V +TG A+GIG + L EG++ + +LDI A +++ + G R DV
Sbjct: 6 RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAVAESIGG-IG-----LRCDV 58
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 365
TD E + V E GG+DV NA + D IG Y+K++ VNV ++
Sbjct: 59 TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A+ M G ++ +S+A L H P+Y K V+ F I + + G
Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176
Query: 546 VRVLTVCFGATDTALLTRRET 608
+ V T+C G T+T +L R +
Sbjct: 177 IAVHTICPGITETGVLGDRRS 197
>UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Nocardioides sp. (strain BAA-499 / JS614)
Length = 246
Score = 76.6 bits (180), Expect = 5e-13
Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 6/193 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K+ +TGA GIG+++ L EG + + D+ +A K L+ + +DV
Sbjct: 7 KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 371
TD +++ VV G IDV++NNA A ++ + + I +N+ ++ ++ K
Sbjct: 62 TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
+ IM G+V+N+ S A S +Y A K V+ FS R +++ V
Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176
Query: 552 VLTVCFGATDTAL 590
V VC G TDTAL
Sbjct: 177 VNCVCPGPTDTAL 189
>UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep:
Short chain dehydrogenase - Mycobacterium avium (strain
104)
Length = 594
Score = 76.6 bits (180), Expect = 5e-13
Identities = 56/195 (28%), Positives = 92/195 (47%), Gaps = 6/195 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E + ++ +TGA GIG + L +G + + I+D + A + G Y
Sbjct: 322 EVRGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVY 380
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
+ DV+DE + V E G +D+++NNA + G + + N A++ ++ +
Sbjct: 381 QVDVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGV 438
Query: 378 EIMGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
+ G G+GGT+INV+S AA S M Y TK+AVL S + R + F+
Sbjct: 439 IWGSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FAD 496
Query: 540 TGVRVLTVCFGATDT 584
G+ V VC G +T
Sbjct: 497 EGITVTAVCPGFVNT 511
>UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Thermotoga|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Thermotoga maritima
Length = 257
Score = 76.2 bits (179), Expect = 6e-13
Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K KV +TG GIG+++ + L G + I+DI EE + E+ K G + FY
Sbjct: 11 KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
DVT EE G + + G +D+ +NNA + N + +KK I+VN+ + S
Sbjct: 69 DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
M + GK +IN++S++ + + Y A+K+ V+ + + ++
Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183
Query: 540 TGVRVLTVCFGATDTALL 593
G+RV ++ G T L+
Sbjct: 184 YGIRVNSISPGYIRTPLI 201
>UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=1; Bacillus halodurans|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus
halodurans
Length = 247
Score = 76.2 bits (179), Expect = 6e-13
Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 7/197 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+DKV +TGA GIG+ +V+ +++G I EA + ++ LN G K Y S
Sbjct: 4 RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61
Query: 204 DVTDEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362
D++ F+ + +VV + +D+++NNA + D +++ ++VN T
Sbjct: 62 GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
A+ M + GK ++NV SV + Y A+K A++ + + R +S+
Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176
Query: 543 GVRVLTVCFGATDTALL 593
G+ + + G +T ++
Sbjct: 177 GISINAIAPGMIETEMI 193
>UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6;
Clostridium|Rep: Predicted short-chain dehydrogenase -
Clostridium acetobutylicum
Length = 262
Score = 76.2 bits (179), Expect = 6e-13
Identities = 53/193 (27%), Positives = 95/193 (49%), Gaps = 5/193 (2%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
V ITGA+TGIG + RI G + ++ +E K L +EL K + D++
Sbjct: 3 VLITGASTGIGYEITRIFARNG--YDVVITARDE--KRL-IELAKNINTKVTVIKKDLSR 57
Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 395
+ + N + + +D+++NNA M D+ G++ K+ + ++ +K++ I+ +
Sbjct: 58 PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115
Query: 396 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
+ G ++NV+S + + +Y+ATK+ VL F+ IG E K V+V
Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173
Query: 561 VCFGATDTALLTR 599
+C GAT T R
Sbjct: 174 LCPGATATEFSKR 186
>UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 258
Score = 76.2 bits (179), Expect = 6e-13
Identities = 59/196 (30%), Positives = 99/196 (50%), Gaps = 8/196 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K+ +TG A+G+G + R L EG + + DI AG + + EL G F R DV
Sbjct: 6 KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 371
T E +L +L + G +DV++NNA + ++ +I + + + VN+ ++
Sbjct: 64 TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG-- 545
+ +M + KGG++INVSS+ A+ V Y A+K+ V S + H ++ G
Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177
Query: 546 VRVLTVCFGATDTALL 593
+RV ++ G DT LL
Sbjct: 178 IRVNSLHPGYIDTPLL 193
>UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Methylobacterium
sp. 4-46
Length = 255
Score = 76.2 bits (179), Expect = 6e-13
Identities = 56/194 (28%), Positives = 93/194 (47%), Gaps = 6/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG A GIG + R +EG + + DI EAG + N + +F DV
Sbjct: 7 KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 371
T + + + V +GG+DVV+N A + +S+ + +++ VNV
Sbjct: 62 TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A+ +M K G+GG +IN+SSV+ + H + Y A+K AV + + G+R
Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180
Query: 552 VLTVCFGATDTALL 593
++ G T+T +L
Sbjct: 181 CNSIHPGFTETDML 194
>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
bacterium HTCC2150
Length = 279
Score = 76.2 bits (179), Expect = 6e-13
Identities = 55/205 (26%), Positives = 98/205 (47%), Gaps = 8/205 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYR 200
K+K V +TGAA G+G + L +G ++ + D+ AE+ +S+Q + ++
Sbjct: 23 KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 374
DVT E+ ++ V G +DV+INNA + + D + I + + +
Sbjct: 80 CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139
Query: 375 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CIG-RPEHFSK 539
+I GK + GKGG +IN+SS+ AL + ++ Y +K + Q +N +G P +
Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPHNIRV 199
Query: 540 TGVRVLTVCFGATDTALLTRRETRH 614
G+ T+ ++T E RH
Sbjct: 200 CGIGPGTILTDMVADVIMTSPEARH 224
>UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Bacillus sp. B14905
Length = 254
Score = 76.2 bits (179), Expect = 6e-13
Identities = 54/195 (27%), Positives = 95/195 (48%), Gaps = 6/195 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
++KV ITG TGIG+ + EG K I I DI E++G ++ + +G + F
Sbjct: 7 ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 365
DV++E+ + + + + +D++ NNA L + + + + +NVT +
Sbjct: 65 DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ +M K + G+VIN SS+A LT + +Y A+K AV + ++ G
Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTK--DAAMEYAPYG 179
Query: 546 VRVLTVCFGATDTAL 590
VRV ++ G DT +
Sbjct: 180 VRVNSIHPGYIDTGM 194
>UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Short-chain dehydrogenase/reductase SDR - Candidatus
Nitrosopumilus maritimus SCM1
Length = 253
Score = 76.2 bits (179), Expect = 6e-13
Identities = 51/173 (29%), Positives = 95/173 (54%), Gaps = 10/173 (5%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
DKV +TGA++ IG+ + + ++EG K I I E ++ + E+ ++ + T D
Sbjct: 5 DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 365
+ DE L ++N ++ G ID+++NNA +ND I + +K I VN+ + T
Sbjct: 62 LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCI 515
KA ++ K + K G+++N+ S++ A+ + H + +Y ATK+A+ F+ I
Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170
>UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Staphylococcus
epidermidis|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 255
Score = 75.8 bits (178), Expect = 8e-13
Identities = 53/188 (28%), Positives = 100/188 (53%), Gaps = 7/188 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV + G ATGIG+++ L G +I I D+ G+ ++++ G KT + D+
Sbjct: 13 KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 377
T + I++ VV+E G ID+++NNA ++ +D+ I Y++ + E+N++ +
Sbjct: 72 THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129
Query: 378 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ +G+ KG G++INVSSV L ++ Y +K+ V + + R +S+ G+
Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187
Query: 549 RVLTVCFG 572
+V + G
Sbjct: 188 KVNAIAPG 195
>UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 262
Score = 75.8 bits (178), Expect = 8e-13
Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+ KV ITG A GIG R L G +AILD+ + ++L E+ ++ G + F+
Sbjct: 11 RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 362
DVT E + +V G +DV++NNA + ++ +++ ++VNV +
Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 494
T AI + GG+++N+SS+ + +P Y A+K+AV
Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169
>UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodopseudomonas palustris
(strain BisB5)
Length = 263
Score = 75.8 bits (178), Expect = 8e-13
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 7/195 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+VV +TG A+GIG + +G + + DI + G VE + G++ ++ R+DV
Sbjct: 21 RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
TDE ++ V G +DV NNA + S I ++ I VN+ + S
Sbjct: 79 TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ + S G G ++N +SV L Y A K V+ + C + ++G+
Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193
Query: 549 RVLTVCFGATDTALL 593
R+ VC G +T L+
Sbjct: 194 RINAVCPGYIETPLV 208
>UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like
protein; n=1; Reinekea sp. MED297|Rep: Short-chain
alcohol dehydrogenase-like protein - Reinekea sp. MED297
Length = 672
Score = 75.8 bits (178), Expect = 8e-13
Identities = 52/177 (29%), Positives = 92/177 (51%), Gaps = 8/177 (4%)
Frame = +3
Query: 6 NMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185
N+ KVV ITG ++GIG++ L G I AE+ ++ +++ S G
Sbjct: 377 NLEERLNGKVVLITGGSSGIGKATAMRLSKAGATVIICARDAEKLRRA-HLDIESTGGTV 435
Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVN 341
+++D+T + + + +E G+D++INNA ++M D + +++ IE+N
Sbjct: 436 VS-HQADITQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELN 494
Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 512
A + TLKA+ +M + + G VIN+SS+ L+ S Y A+K+A+ FS C
Sbjct: 495 YLASVAITLKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548
>UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC80593 protein -
Strongylocentrotus purpuratus
Length = 258
Score = 75.4 bits (177), Expect = 1e-12
Identities = 56/201 (27%), Positives = 97/201 (48%), Gaps = 7/201 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+ V ITG+A G+G + + G + + +LDI E K L EL SK G Y D+
Sbjct: 63 RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
+ + ++ + ++ G +D++INNAA ++ S +K EVN A I T
Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG-RPEHFSKTGV 548
+ M K G V+N++S+A + + Y A+KSA++ F+ +G + TGV
Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237
Query: 549 RVLTVCFGATDTALLTRRETR 611
+ VC + + + ++R
Sbjct: 238 HLSLVCPSYMEEGMFAQCKSR 258
>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
dehydrogenase/reductase family; n=1; Photobacterium
profundum|Rep: Hypothetical oxidoreductase, short-chain
dehydrogenase/reductase family - Photobacterium
profundum (Photobacterium sp. (strain SS9))
Length = 255
Score = 75.4 bits (177), Expect = 1e-12
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV I+G +GIGE+ R+ +G + ++ E G+ L ELN++Y T F ++D+
Sbjct: 10 KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
T + + E GGID NNA + S I+ + I N+
Sbjct: 67 TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ + IM K GT++N++S+ ++ Y ++ AVL + ++K GV
Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTR--SAAVEYAKQGV 181
Query: 549 RVLTVCFGATDTALLTR 599
RV V GA DT + R
Sbjct: 182 RVNAVAPGAIDTPIFER 198
>UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4;
Legionella pneumophila|Rep: Acetyoacetyl CoA reductase -
Legionella pneumophila (strain Corby)
Length = 248
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/172 (29%), Positives = 84/172 (48%), Gaps = 7/172 (4%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGKSLQVELNSKYGNKTKFYRS 203
+ VV ITG IG +V + LD KH+ LD+ + G+ +L ++ F
Sbjct: 4 NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365
DVTD E ++ +++E GGIDV+INNA + D++ + + + VN+ + T
Sbjct: 63 DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
+ +E M G+ ++NVSSV A Y A+K+ V F+ + +
Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLAQ 171
>UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein]
reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
3-oxoacyl-[acyl-carrier protein] reductase -
Arthrobacter aurescens (strain TC1)
Length = 261
Score = 75.4 bits (177), Expect = 1e-12
Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 6/196 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K V +TGA +G+G +V + L EG I + D++E++ + + NS + +DV
Sbjct: 9 KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
D + I+N V+E G +DV++NNA + S +++ ++VNV L +T
Sbjct: 67 GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A+ H G ++N +SV+ + + Y A+K AV+ F+ + +++ GVR
Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180
Query: 552 VLTVCFGATDTALLTR 599
V G T LL +
Sbjct: 181 CNAVAPGPVLTPLLQK 196
>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
marine gamma proteobacterium HTCC2143|Rep: Short-chain
dehydrogenase/reductase - marine gamma proteobacterium
HTCC2143
Length = 264
Score = 75.4 bits (177), Expect = 1e-12
Identities = 58/200 (29%), Positives = 102/200 (51%), Gaps = 6/200 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M++ + KV ITG +GIGE+ I + EG + + +EE G+++ ++ G+K
Sbjct: 1 MTNRLQGKVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIA----NRLGDKA 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTA 350
+ ++DV+ EE ++ V+ G +DV+ NNA DSI G +++ +++
Sbjct: 56 HYIKADVSKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSS 115
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
++ AIE M K +G GG +IN +S+AA+ +Y A K+AV ++ G
Sbjct: 116 VVLGIRYAIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VE 170
Query: 531 FSKTGVRVLTVCFGATDTAL 590
G+RV + GA T +
Sbjct: 171 LGPLGIRVNCISPGAIATPI 190
>UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella pealeana ATCC
700345
Length = 254
Score = 75.4 bits (177), Expect = 1e-12
Identities = 56/191 (29%), Positives = 99/191 (51%), Gaps = 6/191 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS KV ITGAA G+G + R++ EG + + + DI E GK E+ + GN +
Sbjct: 1 MSGRLIGKVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNS 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
F DVT E + ++N + + G +++++NNAA++ +++ +++ VN +
Sbjct: 56 LFIEHDVTKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDS 115
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+ A+ +M K SG GG++IN+SS +A+ Y A+K+A+ S +
Sbjct: 116 VFLRIHYALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCS 172
Query: 531 FSKTGVRVLTV 563
+K VR T+
Sbjct: 173 QTKNNVRCNTL 183
>UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Delftia acidovorans SPH-1|Rep: Short-chain
dehydrogenase/reductase SDR - Delftia acidovorans SPH-1
Length = 301
Score = 75.4 bits (177), Expect = 1e-12
Identities = 62/200 (31%), Positives = 93/200 (46%), Gaps = 6/200 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
++ K V +TGA+ GIGE R L G K + I + K L EL +F
Sbjct: 47 DFSQKTVLVTGASMGIGEVFARELARRGAKVVLIARSRDRLEK-LASELPG-----AEFL 100
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALIT 359
D+ + +AV D+++NNA ++ + ++ I++NV AL+
Sbjct: 101 VEDLATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNVGALVE 160
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
T + + + GG VIN++S AA M +Y ATK+ VL FS + +
Sbjct: 161 LTHLCLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW--AEYRP 214
Query: 540 TGVRVLTVCFGATDTALLTR 599
GVRVL +C GATDTA R
Sbjct: 215 RGVRVLALCPGATDTAFFAR 234
>UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2;
Euryarchaeota|Rep: Predicted short chain dehydrogenase -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 253
Score = 75.4 bits (177), Expect = 1e-12
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 7/198 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K KV ITGA GIG+S+ + +EG I I E + + E+NS G+ +
Sbjct: 4 KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERL-EQITNEINSNGGDASACI-G 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 362
DVT +E ++ + + G ID+++NNA +M+D + + + K I+VN+T +
Sbjct: 62 DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
I M K++ GG +I +SSV L Y A+K V+ + + K
Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176
Query: 543 GVRVLTVCFGATDTALLT 596
+R + G +T + T
Sbjct: 177 NIRSNVIAPGTVNTEIAT 194
>UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 249
Score = 74.9 bits (176), Expect = 1e-12
Identities = 58/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K+ +TGA++GIG + L + G K + I + + L+ ++ +K G + DV
Sbjct: 7 KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 371
D + +V G ID+++NNA LM +D + +++ ++VNV L+ +T
Sbjct: 65 VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124
Query: 372 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ +++ +HS G V N+SS+A + +Y ATK AV FS+ + R E K G+
Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179
Query: 549 RVLTVCFGATDTAL 590
RV + GA T L
Sbjct: 180 RVTCIQPGAVATEL 193
>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
protein) reductase - Leptospira interrogans
Length = 259
Score = 74.9 bits (176), Expect = 1e-12
Identities = 52/199 (26%), Positives = 100/199 (50%), Gaps = 7/199 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
MS +++ KV +TGAA+ G+G ++ + EG I ++D+ +E + ++ ++G
Sbjct: 5 MSKQFEGKVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGV 63
Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362
KT +VT E ++ V ++ G +D ++NNA ++ D++ I + E ++
Sbjct: 64 KTLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDV 121
Query: 363 TLKAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
LK + +M K++ + G ++N+SSV+ LT Y ++K+ V+ + R
Sbjct: 122 NLKGVFLMTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR-- 179
Query: 528 HFSKTGVRVLTVCFGATDT 584
F+ V V VC G T
Sbjct: 180 EFAGRNVLVNAVCPGYVQT 198
>UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii
KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
KSM-K16)
Length = 257
Score = 74.9 bits (176), Expect = 1e-12
Identities = 53/189 (28%), Positives = 101/189 (53%), Gaps = 8/189 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K +TG A G+G ++ + L G IAI+DI EA E+ + Y T+ ++DV
Sbjct: 12 KHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYSVNTQSIQADV 70
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVNVTALITSTLK 371
+ EE +++ V++ IDV++NNA ++ D++ + +K+ ++VN+ AL ++ +
Sbjct: 71 SKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQ 130
Query: 372 AIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+GKH G G+++N+SS++A + Y A+K AV + + +++ G
Sbjct: 131 ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLA--SEWAQYG 184
Query: 546 VRVLTVCFG 572
+RV + G
Sbjct: 185 IRVNAIAPG 193
>UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase
- Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 262
Score = 74.9 bits (176), Expect = 1e-12
Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+KV +TGAA GIG ++ + L+D G IA + EE + Q + G+K D
Sbjct: 9 NKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGDKVTPMTHD 63
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
VTDE + I++A +++ ID+++NNA ++ ++K I++N+T
Sbjct: 64 VTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINITGTFLGLH 123
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
I M K +G G ++N+SS +++ ++ Y A+K AV + G+
Sbjct: 124 SVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL--ELGPFGI 178
Query: 549 RVLTVCFGATDTAL 590
RV +V GA +T +
Sbjct: 179 RVNSVHPGAVNTPM 192
>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
Terrabacter sp. DBF63|Rep: Short-chain
dehydrogenase/redutase - Terrabacter sp. DBF63
Length = 252
Score = 74.9 bits (176), Expect = 1e-12
Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS+ KV +TG GIG ++L+D G + + + D++E+AG ++ G+
Sbjct: 1 MSNSLDGKVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAV 57
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVT 347
F R+DVTD ++ A V G +D+ NNA L + ++ + K I VN+T
Sbjct: 58 AFVRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLT 117
Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
+ S +KA EI + G GG++IN +S Y +K V+ +
Sbjct: 118 GVFIS-MKA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--V 172
Query: 528 HFSKTGVRVLTVCFGATDTALLTRRE 605
+S G+RV V G T ++ E
Sbjct: 173 EYSDKGIRVNAVLPGVIQTPMIDALE 198
>UniRef50_Q1Q261 Cluster: Strongly similar to
3-oxoacyl-[acyl-carrier protein] reductase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to 3-oxoacyl-[acyl-carrier protein] reductase -
Candidatus Kuenenia stuttgartiensis
Length = 239
Score = 74.9 bits (176), Expect = 1e-12
Identities = 51/193 (26%), Positives = 100/193 (51%), Gaps = 7/193 (3%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+ +TG + GIG+++ ++ + EG V H +D E+ L+ E +S G+ + ++
Sbjct: 1 MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 377
DVTD +++ +V++ G IDV+INNA ++ D + A + N + +T
Sbjct: 56 DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115
Query: 378 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
+ + +H G + GT+IN++S++ +T Y A K V+ F+ + + + +RV
Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173
Query: 555 LTVCFGATDTALL 593
TV G +T ++
Sbjct: 174 NTVAPGVIETDII 186
>UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain
dehydrogenase/reductase SDR - Acidobacteria bacterium
(strain Ellin345)
Length = 261
Score = 74.9 bits (176), Expect = 1e-12
Identities = 60/196 (30%), Positives = 93/196 (47%), Gaps = 7/196 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+D+VV ITG GIG ++ R + EG I+ +E + + G +
Sbjct: 28 EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 362
DV DE+ + A+ + IDV++NNA L S+ ++ IE N+T
Sbjct: 86 DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
T A+ +M G TV+N SVAA T M Y A+K+ +L F+N + E
Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198
Query: 543 GVRVLTVCFGATDTAL 590
G+RV+++ GATDT +
Sbjct: 199 GIRVISLVPGATDTEI 214
>UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3;
Lactobacillus reuteri|Rep: Short-chain dehydrogenase -
Lactobacillus reuteri
Length = 277
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/202 (32%), Positives = 103/202 (50%), Gaps = 8/202 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY----GNKTK 191
+++VV ITG ++GIG+ L E + AI+ + + LQ E+ K G
Sbjct: 12 RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66
Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371
Y+ DVTD + +L+ V E GGIDV+IN+A L D I + K++ + T+ L
Sbjct: 67 AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125
Query: 372 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
+ I + K +G G +IN+ S+A + +Y ATK+ V+QF N + R E +
Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDNVL-RME-VAD 183
Query: 540 TGVRVLTVCFGATDTALLTRRE 605
GV+VLTV G DT + +
Sbjct: 184 YGVQVLTVNPGPIDTPFFDKAD 205
>UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5;
Proteobacteria|Rep: Short chain dehydrogenase -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 278
Score = 74.9 bits (176), Expect = 1e-12
Identities = 63/203 (31%), Positives = 90/203 (44%), Gaps = 7/203 (3%)
Frame = +3
Query: 12 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 191
S+E V ITGA TGIG + EG + +A+ EEAG +L EL + GN+ +
Sbjct: 27 SNEMNTPTVLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LGNEAE 84
Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTA 350
F +DV E ++ V G IDV +NNA ++ S Y + VNV
Sbjct: 85 FLLADVRFEADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGVNVLG 144
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+ S + +M G++IN+SSVA +Y A+K AV +
Sbjct: 145 TMLSLKHEMRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAAL--E 199
Query: 531 FSKTGVRVLTVCFGATDTALLTR 599
+ GVRV V G T +L R
Sbjct: 200 GAAAGVRVNAVAPGPVATEMLDR 222
>UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16;
Mycobacterium|Rep: Probable oxidoreductase ephD -
Mycobacterium bovis
Length = 592
Score = 74.9 bits (176), Expect = 1e-12
Identities = 57/195 (29%), Positives = 91/195 (46%), Gaps = 6/195 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
D +V +TGA +GIG EG + I I DI E K E+ ++ G Y D
Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 368
V+D E V E G D+V+NNA + ++ + + + VN+ ++
Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ + + G GG ++NVSS+AA + Y +K+A FS+C+ R E GV
Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497
Query: 549 RVLTVCFGATDTALL 593
+ T+C G DT ++
Sbjct: 498 GLTTICPGVIDTNIV 512
>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 256
Score = 74.5 bits (175), Expect = 2e-12
Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 10/200 (5%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+D+V ITGAA+G G + ++ EG K +A DI +E G VE + G + +
Sbjct: 4 EDRVAVITGAASGQGRAAAKLFASEGAKVVAA-DI-DEGGAQRTVEEIKEAGGEATAVKV 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 368
DV+ E ++ + G +DV+ NNA + + G K A V A++ L
Sbjct: 62 DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121
Query: 369 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
K + + KH+ +G G++IN +S+ AL Y A K V+ FS + +
Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179
Query: 534 SKTGVRVLTVCFGATDTALL 593
G+RV +C G DT ++
Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199
>UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=16; Pseudomonas|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Pseudomonas aeruginosa PA7
Length = 266
Score = 74.5 bits (175), Expect = 2e-12
Identities = 55/193 (28%), Positives = 97/193 (50%), Gaps = 7/193 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+ ITGA++GIG ++ L G + + ++ +A +S+ EL ++G + F D+
Sbjct: 3 RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
+ G+L+ + Q + ID+++NNA + ++ ++ IE+N+ AL +
Sbjct: 62 AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117
Query: 372 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+G +GG ++NV+SVAA M Y+A+K+ VL FS G E V
Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175
Query: 549 RVLTVCFGATDTA 587
+V +C G T TA
Sbjct: 176 KVSVLCPGPTRTA 188
>UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Enterobacter sp. 638|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Enterobacter sp.
638
Length = 242
Score = 74.5 bits (175), Expect = 2e-12
Identities = 59/200 (29%), Positives = 100/200 (50%), Gaps = 6/200 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+ E K +V +TGA++GIGE++ R L G++ + + E + V L S+ G+
Sbjct: 1 MNIEKKKRVAVVTGASSGIGEALARELAGNGIQVVLLARRFER----IDV-LASELGHGA 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
++DVTD E + N V Q GG+D++INNA +M + + +++ +E N+
Sbjct: 56 IAIKADVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLG 115
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+T T E+ G ++N+SSVA +Y ATK + +S + R E
Sbjct: 116 AMTVT----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE- 169
Query: 531 FSKTGVRVLTVCFGATDTAL 590
+ +RV+ + GA T L
Sbjct: 170 -LQPDIRVMVIEPGAIATEL 188
>UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family
protein; n=1; Gramella forsetii KT0803|Rep: Short-chain
dehydrogenase/reductase family protein - Gramella
forsetii (strain KT0803)
Length = 271
Score = 74.5 bits (175), Expect = 2e-12
Identities = 50/197 (25%), Positives = 103/197 (52%), Gaps = 6/197 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
++++K V ITG A+GIG + + +++G + ILDI + A + ++++L + F
Sbjct: 3 KFRNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF- 61
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALIT 359
+D+++E + + + +D++INNA ++ ++ + ++VN A +
Sbjct: 62 ETDLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMK 121
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
T + M K K G ++N+SS A++ + M +Y A+K A+ +S+ + +
Sbjct: 122 LTKLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERER 178
Query: 540 TGVRVLTVCFGATDTAL 590
TG++VLTV DT +
Sbjct: 179 TGIKVLTVTPYYIDTGM 195
>UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular
organisms|Rep: Os07g0664000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 572
Score = 74.5 bits (175), Expect = 2e-12
Identities = 59/200 (29%), Positives = 90/200 (45%), Gaps = 9/200 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITG A+GIG++ + G K + I DI ++ G S+ EL G + R DV
Sbjct: 314 KVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL----GPDAAYTRCDV 368
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYKKAIEVNVTALITS 362
DE + V+ G +DV NNA AL D +G + + + VN + + +
Sbjct: 369 ADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFDRVMAVNARSTLAA 428
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
A M G V+ SS A + +P+Y +K+ V+ P ++
Sbjct: 429 VKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEP--MARH 483
Query: 543 GVRVLTVCFGATDTALLTRR 602
G+RV + GAT T LL R+
Sbjct: 484 GLRVNAISPGATRTPLLLRQ 503
>UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=8; root|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Pseudomonas paucimobilis (Sphingomonas paucimobilis)
Length = 250
Score = 74.5 bits (175), Expect = 2e-12
Identities = 52/197 (26%), Positives = 95/197 (48%), Gaps = 7/197 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K + +TG +GIG + V +L+ G ++ + DI +EAG+++ + G K ++R D+
Sbjct: 7 KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVV----ATSGGKAAYFRCDI 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
EE ++ + GG+D NNAA L S+ +++++++NVT T
Sbjct: 62 AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+I+ G G+++N +S A + + Y K AV+ + + K G+
Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177
Query: 549 RVLTVCFGATDTALLTR 599
RV + GA T +L R
Sbjct: 178 RVNALVPGAVRTPMLQR 194
>UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase, chloroplast precursor; n=80; cellular
organisms|Rep: 3-oxoacyl-[acyl-carrier-protein]
reductase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 319
Score = 74.5 bits (175), Expect = 2e-12
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKFYRSDV 209
VV ITGA+ GIG+++ L G K +++ A A ++ +V +YG + + DV
Sbjct: 78 VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
+ ++ + + G IDVV+NNA + D++ I + + I +N+T + T
Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A++IM K K G +IN+SSV L + Y A K V+ FS R V
Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVN 252
Query: 552 VLTVCFGATD 581
V+ F A+D
Sbjct: 253 VVCPGFIASD 262
>UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase;
n=11; Proteobacteria|Rep: D-beta-hydroxybutyrate
dehydrogenase - Bradyrhizobium japonicum
Length = 249
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/201 (25%), Positives = 93/201 (46%), Gaps = 4/201 (1%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K V +TGAA+G+G + R+ EG ++A+ D E+ S+ E+ + G K ++
Sbjct: 2 KGLTVLVTGAASGMGRATARVFAAEGA-NVAVTDYDEQGAISVAKEIAAS-GGSAKAWKL 59
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG--IYKKAIEVNVTALITSTLKA 374
DV D +++ V GG+D+V+NNA + + +I Y+ A + ++T+ +
Sbjct: 60 DVADGGEIKRVVHDVAAHFGGLDIVVNNAGISVRVAIDDETYEDAWARGIAVMLTAHPRI 119
Query: 375 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
I H K ++N++S AL + + Y A K V + + + G+
Sbjct: 120 IRAALPHLRKSKSPRIVNIASTEALGATALHSPYSAAKGGVASLTRSLA--VELGREGIT 177
Query: 552 VLTVCFGATDTALLTRRETRH 614
V +C G TA+ R H
Sbjct: 178 VNCICPGPIRTAITDRISEEH 198
>UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 248
Score = 74.1 bits (174), Expect = 2e-12
Identities = 57/195 (29%), Positives = 94/195 (48%), Gaps = 5/195 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITGA +GIG ++ R+ EG K + + D+A E G +L L + G+ F DV
Sbjct: 7 KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
TDE ++ A V G +D+++ NA + I++ + V+ +I L + I
Sbjct: 64 TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122
Query: 390 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
K + G GG ++N++S+ A Y A K+AV+ + + ++ G+R
Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180
Query: 555 LTVCFGATDTALLTR 599
V G DT LL +
Sbjct: 181 NCVSPGYVDTPLLAK 195
>UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Burkholderiaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 252
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+KV +TGAA+G+G + +L EG + + + DI E+AG++L E+ G+ F R D
Sbjct: 6 NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
+ DE + + + + G +DV++NNAA+ + S+ +++ + N
Sbjct: 61 IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
AI M G+++ +SSVAAL +M Y +K AV + + H ++G
Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176
Query: 549 RV 554
R+
Sbjct: 177 RI 178
>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 271
Score = 74.1 bits (174), Expect = 2e-12
Identities = 56/199 (28%), Positives = 92/199 (46%), Gaps = 4/199 (2%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M + KV +TG A GIGE+ R + G +AILD E+AG + + +G +
Sbjct: 1 MKIDLSGKVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGEC 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
KF+R DV+ + + V+ + ID++++NA + G E + +I L
Sbjct: 59 KFFRCDVSKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNL 116
Query: 369 KAIEIMGK----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
K ++ K H GG ++ + SV + T Y +K AVL + + ++
Sbjct: 117 KGCFLISKFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYA 174
Query: 537 KTGVRVLTVCFGATDTALL 593
G+RV VC G DT +L
Sbjct: 175 HKGIRVNCVCPGTIDTPML 193
>UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Novosphingobium aromaticivorans (strain DSM 12444)
Length = 266
Score = 74.1 bits (174), Expect = 2e-12
Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
++ +TGAA GIGE + R EG + + D +E G ++ +L G + +F R D
Sbjct: 8 NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 377
V+ E +G ++ V+ G +D+++NNA + I KK E AL + +T A+
Sbjct: 66 VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125
Query: 378 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
E H KG G VIN++S+ + Y K AV +S R ++ G+ V
Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183
Query: 555 LTVCFGATDTA 587
+C A A
Sbjct: 184 NVICPAAVSAA 194
>UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP
protein - Arabidopsis thaliana (Mouse-ear cress)
Length = 629
Score = 74.1 bits (174), Expect = 2e-12
Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 19/201 (9%)
Frame = +3
Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNKTKF-----Y 197
+TG A+GIG ++ L ++GV + + D +EE G+ SL E N+K+ F
Sbjct: 11 VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 350
+ DVT+ L + + G +D+ INNA + D +K I V++ A
Sbjct: 70 KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
++ T AI+ M K G +IN+ S A L V PIY A+K+ V+ F+ + +
Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184
Query: 531 FSKTGVRVLTVC--FGATDTA 587
+ + G+R+ +C F TD A
Sbjct: 185 YRRQGIRINVLCPEFIKTDLA 205
>UniRef50_Q2U0U8 Cluster: Dehydrogenases with different
specificities; n=2; Pezizomycotina|Rep: Dehydrogenases
with different specificities - Aspergillus oryzae
Length = 271
Score = 74.1 bits (174), Expect = 2e-12
Identities = 57/212 (26%), Positives = 101/212 (47%), Gaps = 23/212 (10%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN------KTKF 194
+ ITGAA+GIG + +G IA+LD+ + A +++Q E+NS+ + +
Sbjct: 6 IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 350
Y +VTDE ++N+ Q +D V+N A + M G +++ ++VN+T
Sbjct: 66 YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125
Query: 351 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 503
A IM G+ G+++N SS+ + + Y ATK AV+
Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185
Query: 504 SNCIGRPEHFSKTGVRVLTVCFGATDTALLTR 599
+ E ++K G+R+ +C G T+T + T+
Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTK 215
>UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24;
Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE -
Wolinella succinogenes
Length = 247
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/166 (26%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
++ K V ITG++ GIG + R+L + G+K L+ E+ +K G +
Sbjct: 2 KFSGKNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVI 60
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALIT 359
D TDEE F+ + ++ G + ++NNA + ND + I ++ IE N+T+
Sbjct: 61 SFDATDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFI 120
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 497
+ +A++ M K + G+V+N+SS+ + Y A+K ++
Sbjct: 121 GSREALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMI 163
>UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; Frankia|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Frankia sp.
(strain CcI3)
Length = 291
Score = 73.7 bits (173), Expect = 3e-12
Identities = 56/194 (28%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +3
Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221
ITGA++GIG + D G + + + +E + L ++YG + D+ DE
Sbjct: 14 ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72
Query: 222 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 389
+ AV + +D+++NNA + + EV + + + + + G
Sbjct: 73 GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132
Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCF 569
+ G+G TVINVSS + M +Y A+K+ VL FS IG + + GVRVL +C
Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189
Query: 570 GATDTALLTRRETR 611
G TDT TR
Sbjct: 190 GPTDTEFFEVLGTR 203
>UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
dehydrogenase/reductase SDR - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 251
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/196 (29%), Positives = 94/196 (47%), Gaps = 6/196 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K +TGA +GIG ++ EG + +A+ D+ E A + + E+ G R+DV
Sbjct: 7 KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
T E G++ + GG++V++NNA + S +++ + VN+
Sbjct: 62 TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
AI + + SG GG VIN+SS+AAL Y A K +L + G +H + GVR
Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTRA-GAIDHIHE-GVR 176
Query: 552 VLTVCFGATDTALLTR 599
V + G +T ++R
Sbjct: 177 VNCIAPGTVETPWISR 192
>UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 260
Score = 73.7 bits (173), Expect = 3e-12
Identities = 61/201 (30%), Positives = 94/201 (46%), Gaps = 7/201 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K+KVV ITGA++G+G + + + +E+ +L EL K+G K
Sbjct: 2 KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 365
D++ + VV +++INNA + I K+ IEVN+TAL T
Sbjct: 61 DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120
Query: 366 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ GK G G ++NV+SVAA +M +Y+ATK+ VL S + +
Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174
Query: 543 GVRVLTVCFGATDTALLTRRE 605
GV+V +C GAT+T E
Sbjct: 175 GVKVSVLCPGATETGFSNSAE 195
>UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
reductase; n=1; Bacillus sp. SG-1|Rep:
3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus
sp. SG-1
Length = 246
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/195 (27%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K+K ITG+A GIG + + EG K + + D E G + + E + G T FY+
Sbjct: 4 KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 365
DV + E + V+++ G ID++INNA + D++ +++ ++VN+T + T
Sbjct: 62 DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ + + GK G +IN +S + L + Y A+K+AV+ + + F G
Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176
Query: 546 VRVLTVCFGATDTAL 590
+ V V G +T +
Sbjct: 177 INVNAVAPGVIETEM 191
>UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Polaribacter dokdonensis MED152|Rep: Short-chain
dehydrogenase/reductase SDR - Polaribacter dokdonensis
MED152
Length = 259
Score = 73.7 bits (173), Expect = 3e-12
Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 8/193 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K ITGA++G+G+ +I G + I+ +++ + L+ +L K+G D+
Sbjct: 3 KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 365
T+ + N V + ID +INNA IG +++A I++N+ AL T
Sbjct: 62 TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
K + + + GK ++NVSS A+L + +YFATK+ V FSN I H +K
Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174
Query: 546 VRVLTVCFGATDT 584
V V T+ GAT T
Sbjct: 175 VTVTTLMPGATKT 187
>UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase,
putative glucose-1-dehydrogenase; n=1; Pyrococcus
abyssi|Rep: Short-chain alcohol dehydrogenase, putative
glucose-1-dehydrogenase - Pyrococcus abyssi
Length = 240
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/200 (28%), Positives = 97/200 (48%), Gaps = 7/200 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E K KV ITGA+ GIG ++ L GV + EE K + EL +YG +T
Sbjct: 2 ELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLV 60
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALI 356
++DV++ E ++ V+ + G ID++INNA ++ D + + + + I VN+
Sbjct: 61 KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
T + + M K G ++N++S+A V P Y A+K ++ + + R H +
Sbjct: 121 IVTQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA 172
Query: 537 KTGVRVLTVCFGATDTALLT 596
+ V V G DT +L+
Sbjct: 173 -PNILVNAVAPGPVDTDMLS 191
>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=225; cellular organisms|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
cholerae
Length = 244
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/191 (28%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGA+ GIG+++ +L + G K I E+G ++ G+ K +V
Sbjct: 6 KVALVTGASRGIGKAIAELLAERGAKVIGTA--TSESGAQA---ISDYLGDNGKGMALNV 60
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 371
T+ E +L A+ E GG+D+++NNA + D++ + K +E N+T++ +
Sbjct: 61 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
+ M K + G +INV SV + Y A K+ V+ F+ + R + GV
Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175
Query: 552 VLTVCFGATDT 584
V TV G +T
Sbjct: 176 VNTVAPGFIET 186
>UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase;
n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein
reductase - Pseudoalteromonas haloplanktis (strain TAC
125)
Length = 247
Score = 73.3 bits (172), Expect = 4e-12
Identities = 58/201 (28%), Positives = 97/201 (48%), Gaps = 6/201 (2%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M H+ D+VV +TGA GIG+S+V G ++A +DI + + ELN+
Sbjct: 1 MKHQ--DQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNI 57
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
+++ + + AVV++ G +D +IN A A ++ + K I VN+T
Sbjct: 58 VAITANIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTG 117
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+A ++M G +INVSS AALT Y A+K+ V+ + + R
Sbjct: 118 TFLCCREAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--E 171
Query: 531 FSKTGVRVLTVCFGATDTALL 593
+ G+RV T+ G T+T ++
Sbjct: 172 LAPVGIRVNTIVPGPTNTPMM 192
>UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 261
Score = 73.3 bits (172), Expect = 4e-12
Identities = 62/200 (31%), Positives = 92/200 (46%), Gaps = 11/200 (5%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E KV ITG G G++ L + G H+ + DI + + EL + G+ T
Sbjct: 14 EHAGKVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV- 71
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTA 350
DVTDE ++ +V+ GG+D+++NNA L + + G ++ EVNV
Sbjct: 72 TCDVTDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMG 131
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
++ TL A + M SG G V+N+SS AA Y +K AV F+ R
Sbjct: 132 VVICTLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--E 183
Query: 531 FSKTGVRVLTVCFG--ATDT 584
+ GVRV + G TDT
Sbjct: 184 LAAVGVRVNAIAPGLILTDT 203
>UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax
borkumensis SK2|Rep: Oxidoreductase, putative -
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
11573)
Length = 581
Score = 73.3 bits (172), Expect = 4e-12
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 7/201 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K V ITGA +GIG G + DI E + + ++ G + + DV
Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 368
++ + V +E G D+V+NNA +L++ S+ +++ + VN+ +I S L
Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
A +++ + G+ G ++N++S AA S ++P Y +KSAVL FS C+ R E + +
Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487
Query: 549 RVLTVCFGATDTALLTRRETR 611
V +C G +T + R TR
Sbjct: 488 GVSAICPGIINTPI--TRNTR 506
>UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3;
Proteobacteria|Rep: P-cumic alcohol dehydrogenase -
Pseudomonas putida
Length = 252
Score = 73.3 bits (172), Expect = 4e-12
Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KDKV +TGAATGIG ++VR L EG K + I D+ + ++ EL + +
Sbjct: 4 KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 356
DV+D + + A + G IDV++NNA + +SI + + K VNV
Sbjct: 58 DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
L A + G GG +IN++SV A + M Y ++K AV + + R +
Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174
Query: 537 KTGVRVLTVCFGAT--DTALLTRRETRHF 617
K G+ V ++ G T + AL ++ F
Sbjct: 175 KAGISVNSISPGYTHSENALANAQQHEQF 203
>UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 387
Score = 73.3 bits (172), Expect = 4e-12
Identities = 52/185 (28%), Positives = 94/185 (50%), Gaps = 17/185 (9%)
Frame = +3
Query: 63 IGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNK-----TKFYRSDVTDE 218
IG+++ L ++G+ + ++D +EE GK SL + N+K+ K F R DVT+
Sbjct: 36 IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94
Query: 219 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 371
+ GG+D+ +N+A + ++ G++++ I VN+ A+I T
Sbjct: 95 RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
AI+ M + K G +IN+ S + L +V PIY A+K V+ F+ + + + G+R
Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209
Query: 552 VLTVC 566
V +C
Sbjct: 210 VNVLC 214
>UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Candidatus Methanoregula boonei 6A8|Rep:
Short-chain dehydrogenase/reductase SDR - Methanoregula
boonei (strain 6A8)
Length = 253
Score = 73.3 bits (172), Expect = 4e-12
Identities = 52/200 (26%), Positives = 93/200 (46%), Gaps = 6/200 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV+ +TGA+ GIG + + + I + +SL E+ + G+ R+DV
Sbjct: 12 KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 371
T EE + + ++ G +D+++NNA +M ++ I Y+ ++VN T
Sbjct: 71 TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A +IM + K GT+IN++SV + + Y ++KS V+ F+ C + V
Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAKELGAFNITVN 187
Query: 552 VLTVCFGATDTALLTRRETR 611
+ F TD TR + +
Sbjct: 188 AVAPGFIDTDLTADTRSQVK 207
>UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to
ENSANGP00000025535; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000025535 - Nasonia
vitripennis
Length = 254
Score = 72.9 bits (171), Expect = 6e-12
Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 8/199 (4%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
W KV +TGA+ GIG ++V LLD G + ++ +A K ++ ++ + K
Sbjct: 4 WAGKVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRVEKVKEL-IDDRPEAKLHAVE 59
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 362
DVT+EE+ + + + G +DV++NNA L + S+ ++ ++VNV L
Sbjct: 60 CDVTNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVC 119
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCIGRPEHFS 536
T +A+ M + G +I++SS+A V +Y ATK AV + + R E +
Sbjct: 120 TREAVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LA 175
Query: 537 KTGVRVLTVCFGATDTALL 593
T +RV T+ G T L+
Sbjct: 176 GTKIRVTTISPGLVATELM 194
>UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Leptospira interrogans
Length = 247
Score = 72.9 bits (171), Expect = 6e-12
Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K+K V +TG+ GIG EG K+ I G S Q + G+ K + +
Sbjct: 8 KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 377
D+ + I+ ++V+E G +DV++NNA + ++ + K E+ + T +A
Sbjct: 60 DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
K KGG +IN++S+ + + + +Y TK AV+ + + + +G RV
Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177
Query: 558 TVCFGATDT 584
+C G DT
Sbjct: 178 AICPGFIDT 186
>UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus
thuringiensis
Length = 247
Score = 72.9 bits (171), Expect = 6e-12
Identities = 50/194 (25%), Positives = 97/194 (50%), Gaps = 6/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TG A GIG+++ L EG K + + ++EA ++L EL K G+ ++DV
Sbjct: 7 KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
+ E ++ V G +D+++NNA + D + +++ I+VN++++ +T
Sbjct: 66 SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
+ + + + G +I++SS+ Y A K+ +L F+ + +KT V
Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180
Query: 552 VLTVCFGATDTALL 593
V +C G DT ++
Sbjct: 181 VNAICPGFIDTEMV 194
>UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=1;
Oceanobacter sp. RED65|Rep: Putative fatty acyl chain
reductase - Oceanobacter sp. RED65
Length = 252
Score = 72.9 bits (171), Expect = 6e-12
Identities = 49/196 (25%), Positives = 100/196 (51%), Gaps = 6/196 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K+V ITG + +G + V + + + ++++ L V + G + R ++
Sbjct: 10 KIVLITGGSGDLGRASVLEFGKQKCRVYFTYNSSKDSADEL-VASAEESGFEAFPIRCNI 68
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
+D+E ++N +V+++G IDV++NNA + D++ +++ I+ N+ T
Sbjct: 69 SDKEQVNALVNDIVEKEGKIDVLVNNAGIYKDNLFTSMTDEEFEQVIQTNLYGTFYCTKS 128
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
+++M ++ + G ++NVSS+A +T S Y A K AV+ FS + + +R
Sbjct: 129 VVDVMYRN---RCGAIVNVSSIAGVTNSFGQANYSAAKGAVVSFSRTLA--AELAPKNIR 183
Query: 552 VLTVCFGATDTALLTR 599
V TV G D++++ R
Sbjct: 184 VNTVAPGLIDSSMVKR 199
>UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=3; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
sp. (strain RHA1)
Length = 258
Score = 72.9 bits (171), Expect = 6e-12
Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K + +TG A GIG ++V+ EG + D+ EE G+ + E + +F R D+
Sbjct: 6 KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 371
TD + + + +E GGIDV++N A L ++ +++ VNV I +
Sbjct: 65 TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A IM S G G +IN S++ T Y ++K AV ++ + R + +G+R
Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179
Query: 552 VLTV 563
V V
Sbjct: 180 VNAV 183
>UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=1; Marinomonas
sp. MED121|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Marinomonas sp.
MED121
Length = 259
Score = 72.9 bits (171), Expect = 6e-12
Identities = 58/185 (31%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
V +TG A+GIGE++V+ L +G ++ DI EEAG+ L LNS +G K F D+TD
Sbjct: 20 VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77
Query: 216 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 377
E + A ++ G I ++NNAA L S + + + VN+ + K
Sbjct: 78 IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+M + GG++IN+SS + + P Y K+ + + + R T VRV
Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192
Query: 558 TVCFG 572
TV G
Sbjct: 193 TVLPG 197
>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Bacillus coagulans 36D1|Rep: Short-chain
dehydrogenase/reductase SDR - Bacillus coagulans 36D1
Length = 262
Score = 72.9 bits (171), Expect = 6e-12
Identities = 53/203 (26%), Positives = 95/203 (46%), Gaps = 7/203 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
++ KV +TG GIG + L G ++ + D+++E G+ ++ G + F
Sbjct: 5 DFTGKVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFV 62
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALI 356
R+DV+ + + + G ID+++NNA L++ ++ K + +NV +
Sbjct: 63 RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
+ M K GT++N +SVA L + M Y A+K AV+ + G +
Sbjct: 123 LGMKYVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAA 177
Query: 537 KTGVRVLTVCFGATDTALLTRRE 605
+GVRV VC G DT ++ + E
Sbjct: 178 PSGVRVNAVCPGVVDTEMMRKIE 200
>UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 292
Score = 72.9 bits (171), Expect = 6e-12
Identities = 54/202 (26%), Positives = 94/202 (46%), Gaps = 6/202 (2%)
Frame = +3
Query: 6 NMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185
N + + KV F+TG A+GIG +V + EG K +AI+D+ + + ELN ++
Sbjct: 28 NQNGRMEKKVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQRFPGS 86
Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVT 347
T DV++EE + V+ GG+DV+++NA L + + ++K + V++
Sbjct: 87 TISVECDVSNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMAVHLD 146
Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
T A++ K +GGT++ + SV + S Y K + C G
Sbjct: 147 GAFLCTKYAMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CRGVAR 203
Query: 528 HFSKTGVRVLTVCFGATDTALL 593
+K +R +C G T L+
Sbjct: 204 EGAKHNIRANLICPGFVLTPLV 225
>UniRef50_Q2UEK6 Cluster: Dehydrogenases with different
specificities; n=2; Aspergillus|Rep: Dehydrogenases with
different specificities - Aspergillus oryzae
Length = 261
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 9/201 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGA +GIG L + G ++ + + E GK +++++ G++ F +DV
Sbjct: 13 KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
+ E ++ A ++ G +D+ +NNAAL D+ I ++K I VN+ + L
Sbjct: 72 SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
K E+ G GG++IN+SS M Y A K + + + G+
Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187
Query: 549 RVLTVCFG--ATDTALLTRRE 605
RV + G ATD + T +E
Sbjct: 188 RVNALAPGGVATDLTMATMQE 208
>UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60;
Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter
sphaeroides (Rhodopseudomonas sphaeroides)
Length = 256
Score = 72.9 bits (171), Expect = 6e-12
Identities = 52/188 (27%), Positives = 95/188 (50%), Gaps = 4/188 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K ITG+A GIG + + EG + +AI DI EA ++ E+ G DV
Sbjct: 6 KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 383
TD+ + ++ G ID+++NNAAL + + + I +++ + ++ TL ++
Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120
Query: 384 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+ + +GG+GG +IN++S A ++ +Y ATK+AV+ + G + + G+ V
Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178
Query: 558 TVCFGATD 581
+ G D
Sbjct: 179 AIAPGVVD 186
>UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Putative uncharacterized protein - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 247
Score = 72.5 bits (170), Expect = 8e-12
Identities = 60/194 (30%), Positives = 95/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV+ ITGA++GIGE++ + G K I + EE K ++ ++ + G + ++ +DV
Sbjct: 5 KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
TD E + + G IDV INNA LM S+ I + + I+VN+ +
Sbjct: 63 TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A I + G IN+ SVA+L +Y ATK AV S + E + VR
Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179
Query: 552 VLTVCFGATDTALL 593
V ++ GA ++ L+
Sbjct: 180 VTSLYPGAIESELV 193
>UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Xanthobacter autotrophicus Py2|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Xanthobacter sp. (strain Py2)
Length = 261
Score = 72.5 bits (170), Expect = 8e-12
Identities = 54/193 (27%), Positives = 92/193 (47%), Gaps = 6/193 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KDK + ITGAA GIG ++ + L +G + I + D++E A +++ E+ + G
Sbjct: 5 KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
DV +L+ V G +DV+ NNA + ++ + ++ +VN ++
Sbjct: 63 DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+AI+ K GG GG ++N +S+AA + Y A+K AV+ + R F K
Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178
Query: 546 VRVLTVCFGATDT 584
+ V C G T
Sbjct: 179 ITVNAFCPGVVAT 191
>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Roseiflexus sp. RS-1
Length = 246
Score = 72.5 bits (170), Expect = 8e-12
Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 5/196 (2%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K KV +TGA GIG++ EG H+A++DI AG V ++ + ++
Sbjct: 4 KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDI-NMAGAEATVAEITRLDGRALAVQA 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
DV+ ++ V+ G IDV++NNA + D+ + K E A+I LK + +
Sbjct: 62 DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119
Query: 384 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ H +G G++INVSS+ L + Y ATK V+ + R +GV
Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177
Query: 549 RVLTVCFGATDTALLT 596
RV V G T ++T
Sbjct: 178 RVNAVTPGFIATEMIT 193
>UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2;
Actinobacteria (class)|Rep: Putative short chain
dehydrogenase - marine actinobacterium PHSC20C1
Length = 265
Score = 72.5 bits (170), Expect = 8e-12
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 6/208 (2%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+H K++ V ITG +GIG + + G + + + D++ A +S+ E+ G+
Sbjct: 1 MTHPLKNQTVLITGGGSGIGRLLALGAAERGAR-VVVWDLSAAAAESVCEEILGA-GHHA 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 350
+ + DV+D +NA ++ G +DV+INNA L++ S ++ I VN A
Sbjct: 59 EAFTVDVSDRN----AVNAAAKKTGQVDVLINNAGIVTGKNLLDASDEAIERTIRVNTLA 114
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
L T +G + GTV+ +SS A L Y A+K A L F+ +
Sbjct: 115 LFWVTRA---FLGNMIANRRGTVVTISSAAGLVGVAKQTDYSASKFAALGFAESLRVELS 171
Query: 531 FSKTGVRVLTVCFGATDTALLTRRETRH 614
TGV L VC T + +T++
Sbjct: 172 KENTGVNSLVVCPYFVSTGMFEGVQTKY 199
>UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;
n=13; Bacteria|Rep: Uncharacterized oxidoreductase
SSP1627 - Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 246
Score = 72.5 bits (170), Expect = 8e-12
Identities = 58/196 (29%), Positives = 91/196 (46%), Gaps = 7/196 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
KDKVV ITGA++GIGE V +L + G K L + L+ ++ K G + +
Sbjct: 5 KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362
+DVT + ++ + G IDV+INNA LM S + + I+VN+ ++
Sbjct: 60 TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ M K K G +IN++SVA +Y TK AV + + + E +
Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176
Query: 543 GVRVLTVCFGATDTAL 590
+R + GA T L
Sbjct: 177 NIRTTILSPGAVSTEL 192
>UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular
organisms|Rep: Alcohol dehydrogenase - Bordetella
parapertussis
Length = 252
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 5/188 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K +TGA +G GE + EG K + + DI E G+ + +N+ G + F R+DV
Sbjct: 6 KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
+D +L A ++ GG+D+V+NNA + + + + E + +K+I +
Sbjct: 64 SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122
Query: 390 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
+H GG+ IN++S AA+ + Y +K AV+ S + V
Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182
Query: 555 LTVCFGAT 578
+ GAT
Sbjct: 183 VNPVIGAT 190
>UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase, putative; n=26; Gammaproteobacteria|Rep:
3-oxoacyl-(Acyl carrier protein) reductase, putative -
Idiomarina loihiensis
Length = 254
Score = 72.1 bits (169), Expect = 1e-11
Identities = 59/204 (28%), Positives = 93/204 (45%), Gaps = 15/204 (7%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KD V+ ITG A G+G ++ +G K +A++DI + Q + K Y
Sbjct: 4 KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 338
D+TDEE + + QE GIDV++NNA L+ D + I ++ ++V
Sbjct: 63 DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122
Query: 339 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518
N+T +A M K GK G +IN+SSVA + Y ATK+ V+ +
Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMTVTWA 179
Query: 519 RPEHFSKTGVRVLTVCFGATDTAL 590
R + G+R + G +T +
Sbjct: 180 R--ELGRYGIRCGAIAPGFIETPM 201
>UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2;
Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases
- Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
NCIB 8253 / DSM158)
Length = 247
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/191 (29%), Positives = 93/191 (48%), Gaps = 6/191 (3%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
+ ITGA +GIG R EG +A++D E A QV + G+ + DVTD
Sbjct: 10 IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAA---QVTADETGGH---VFALDVTD 62
Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 377
E ++ + GGID ++N+A ++ D IG+ +++ ++VN+T A+
Sbjct: 63 EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+ K ++N++S AL S Y A+K+AV+ FS I + VRV
Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176
Query: 558 TVCFGATDTAL 590
+C GAT+T +
Sbjct: 177 IICPGATETPM 187
>UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caulobacter sp. K31|Rep: Short-chain
dehydrogenase/reductase SDR - Caulobacter sp. K31
Length = 249
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 6/200 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS + +V +TGA++G GE+V L G K +A+ E+ ++L + G +
Sbjct: 1 MSMDLSGRVALVTGASSGFGEAVALDLAKAGAK-VALAARREDRLRALAQRITDA-GGQA 58
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
+ +D TDE + G +D++INNA +M +G ++ +E+N+
Sbjct: 59 QVIVADFTDEHQAQRAVRETEAAFGWLDILINNAGVMYLEPVATADLGRWRSMLELNLLG 118
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
LI +T A+ M + K G ++N++S A + + Y A+K V+ FS + + H
Sbjct: 119 LIAATQAALPGM---TARKDGHIVNIASTAGHIANPLSAAYSASKFGVIGFSESLRKEVH 175
Query: 531 FSKTGVRVLTVCFGATDTAL 590
K +RV + G T L
Sbjct: 176 --KDNIRVTVISPGMAATEL 193
>UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain
dehydrogenase/reductase SDR - Parvibaculum
lavamentivorans DS-1
Length = 287
Score = 72.1 bits (169), Expect = 1e-11
Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 8/195 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITG +GIG V + L EG K +A D+ + G++++ EL G + R++V
Sbjct: 7 KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 374
E+ +++ V++ G +D++ NNA +G + I++N V L+ +
Sbjct: 62 AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119
Query: 375 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC--IGRPEHFSKTG 545
+ H K G++I+ +SVA L + +Y A K+AV FS C + HF
Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAPHF---- 175
Query: 546 VRVLTVCFGATDTAL 590
VR +C G T++
Sbjct: 176 VRSNAICPGGIATSI 190
>UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Chlorobium/Pelodictyon group|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Chlorobium phaeobacteroides (strain DSM 266)
Length = 280
Score = 72.1 bits (169), Expect = 1e-11
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K +TGAA+GIG ++ L++ G + + + DI + AG + G DV
Sbjct: 8 KNAIVTGAASGIGFALAVGLIERGAR-VWVADI-DSAGVERAA---ASLGAGAHPVTLDV 62
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
D F ++ V ++ GGID + NNA +++ + I+VN+ ++ TL
Sbjct: 63 RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A +M + + G ++N +S+A L + ++ Y TK AV+ FS+ + R E + GVR
Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177
Query: 552 VLTVCFGATDTALL 593
V +C DT LL
Sbjct: 178 VSAICPAGVDTPLL 191
>UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella woodyi ATCC
51908
Length = 255
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/191 (26%), Positives = 94/191 (49%), Gaps = 6/191 (3%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
VFITG A+GIG ++VR +++G ++ +D +AG++L L+ G + F+ DVTD
Sbjct: 15 VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73
Query: 216 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 377
+ ++ Q+ G +D++INN +D+ G+ +K+ + +N+ + ++ A
Sbjct: 74 TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133
Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+M + K G +IN SS A M Y K+ + + + + S+ V +
Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAKDYGESRVRVNAI 190
Query: 558 TVCFGATDTAL 590
+ AT L
Sbjct: 191 VPGWVATQRQL 201
>UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid
dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or
20-beta)-hydroxysteroid dehydrogenase - Mycobacterium
bovis
Length = 260
Score = 72.1 bits (169), Expect = 1e-11
Identities = 55/200 (27%), Positives = 98/200 (49%), Gaps = 6/200 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS KV ++G A G+G S VR ++ EG K + DI +E GK++ EL +
Sbjct: 1 MSGRLIGKVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAA 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 350
++ DVT + ++ V GG+ V++NNA ++N ++ +++ ++VN+T
Sbjct: 56 RYVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTG 115
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
+ ++ M K +G G++IN+SS+ L + Y ATK AV +
Sbjct: 116 VFLGIRAVVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--E 170
Query: 531 FSKTGVRVLTVCFGATDTAL 590
+G+RV ++ G T +
Sbjct: 171 LGPSGIRVNSIHPGLVKTPM 190
>UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative
alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative alcohol dehydrogenase -
Nasonia vitripennis
Length = 240
Score = 71.7 bits (168), Expect = 1e-11
Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 4/152 (2%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ---VELNSKYGN-KTKF 194
+KV +T GIG S + L +++A+LD+ + + L ++G K +
Sbjct: 5 NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374
Y +V + E F + VV+ +G +D+++ NAA+ D+ I+VN+ +I TL A
Sbjct: 63 YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120
Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 470
+E MG H KGG V+N++S L + + +
Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152
>UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase -
Oceanobacillus iheyensis
Length = 244
Score = 71.7 bits (168), Expect = 1e-11
Identities = 57/198 (28%), Positives = 100/198 (50%), Gaps = 6/198 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
++KV ITG A G+G S VR+ EG K + D+ EE G +L EL G KF +
Sbjct: 5 ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 365
DVT+ + + +++ + G ++V++NNA LM + Y+K I++N ++
Sbjct: 60 DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+KA+ + +G G+++N+SS+ + V Y +K AV + G
Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172
Query: 546 VRVLTVCFGATDTALLTR 599
+RV +V G +T ++T+
Sbjct: 173 IRVNSVHPGVIETPMVTK 190
>UniRef50_Q13H99 Cluster: Putative short-chain
dehydrogenase/reductase; n=3; Proteobacteria|Rep:
Putative short-chain dehydrogenase/reductase -
Burkholderia xenovorans (strain LB400)
Length = 274
Score = 71.7 bits (168), Expect = 1e-11
Identities = 52/195 (26%), Positives = 96/195 (49%), Gaps = 12/195 (6%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
++KV +TGA G+G + R L G + +A++DI EA ++ ++ G + R+
Sbjct: 11 ENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GERAMSVRT 65
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKAIEVNVT 347
DV+ E +++AV++ G ID++ NNAA+++D S+ ++ +A+ VN+
Sbjct: 66 DVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRAMAVNLR 125
Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
+ AI M + G GG++I+ SS M Y A+K+ + S +
Sbjct: 126 GAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSKSVA--A 180
Query: 528 HFSKTGVRVLTVCFG 572
+ K +R T+ G
Sbjct: 181 QYGKERIRSNTIQIG 195
>UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium gilvum
PYR-GCK
Length = 543
Score = 71.7 bits (168), Expect = 1e-11
Identities = 58/193 (30%), Positives = 86/193 (44%), Gaps = 4/193 (2%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
D +V +TGAA+GIG + G + I D+ AG L + G Y D
Sbjct: 274 DTLVAVTGAASGIGRATALAFAHHGAD-VVISDV-NAAGLDETARLVTSAGVHAYPYTVD 331
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT--STLKAIE 380
V D V E G DVV+NNA + + + A E + I +
Sbjct: 332 VADAAAVEAFAEQVCAEHGVPDVVVNNAGVGHAGFFLDTPAEEFDRVLDINFGGVVNGCR 391
Query: 381 IMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
GK G GG ++NV+S+A+ T +VM Y +K+AV FS+C+ R E G+ +
Sbjct: 392 SFGKRLADRGVGGHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCL-RAE-LDSFGIGL 449
Query: 555 LTVCFGATDTALL 593
T+C G T ++
Sbjct: 450 TTICPGFISTNIV 462
>UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep:
3-oxoacyl-(Acyl-carrier protein) reductase -
Flavobacteriales bacterium HTCC2170
Length = 245
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/204 (25%), Positives = 96/204 (47%), Gaps = 6/204 (2%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KDK+ +TG A GIG++V + EG + I+D+ + G+++ + + G K +++
Sbjct: 4 KDKIAVVTGGARGIGQAVSELFAKEGAT-VIIMDLLPQ-GQAVAEGIIAS-GGKAEYHSL 60
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 365
VT++ G+ ++V + G ID++INNA + D S + IEVN+ + T
Sbjct: 61 SVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVFICT 120
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ M K G +++ +S L + Y ATK+ V+ + F K G
Sbjct: 121 QAVVPYM---KASKYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKT--WTVEFGKYG 175
Query: 546 VRVLTVCFGATDTALLTRRETRHF 617
+ + G T T ++ + HF
Sbjct: 176 ITANAIAPGFTMTDMVKQIPEEHF 199
>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Marinomonas sp. MED121|Rep: Short-chain
dehydrogenase/reductase SDR - Marinomonas sp. MED121
Length = 255
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 7/189 (3%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
+KD+VV ITGA+ G+G+ + +G K +A+ D+ A L EL + G +
Sbjct: 4 FKDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTEL-IEQGYEVFSQP 61
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALIT 359
DV++E+ ++ G +DV INNA L + +++ +++NV +
Sbjct: 62 CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
I M K GG + N+SSVA ++ + M Y A+K AV+ + + + +
Sbjct: 122 CMKYQIPHMIKQG---GGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGR 176
Query: 540 TGVRVLTVC 566
G+RV +VC
Sbjct: 177 AGIRVNSVC 185
>UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=7; Gammaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella sp. (strain
ANA-3)
Length = 253
Score = 71.7 bits (168), Expect = 1e-11
Identities = 58/200 (29%), Positives = 93/200 (46%), Gaps = 7/200 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+K +TGAA GIG++++R LL EG + +A A+ + +L+V N +K + D
Sbjct: 5 NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 365
VTD + ++ + G +D++INNA L +D I ++ VN +
Sbjct: 60 VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
L + G G ++N SSV A S + Y +K+AV + C + G
Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175
Query: 546 VRVLTVCFGATDTALLTRRE 605
VRV V G DT +L + E
Sbjct: 176 VRVCAVAPGRVDTPMLRQYE 195
>UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=18; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Arthrobacter sp.
(strain FB24)
Length = 263
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 18/208 (8%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 200
K V ITG A+G+G + R L D G + ++D+ G++ ELN+ G T F
Sbjct: 4 KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEVN--- 341
+DVT EE + A V G + +V+N A + + + + I++N
Sbjct: 63 ADVTSEEQVQAAVAAAVA-LGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121
Query: 342 ---VTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 509
V L + + A E + GG + G +IN +SVAA P Y A+K AV +
Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181
Query: 510 CIGRPEHFSKTGVRVLTVCFGATDTALL 593
I R +++ +RV+T+ G +T ++
Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207
>UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=3;
Oligohymenophorea|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Tetrahymena
thermophila SB210
Length = 260
Score = 71.7 bits (168), Expect = 1e-11
Identities = 54/204 (26%), Positives = 102/204 (50%), Gaps = 18/204 (8%)
Frame = +3
Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
V +TG +G+GE+ V LL++GV+ + I D EE G +++ +KYG ++ +F + DV
Sbjct: 8 VALVTGGTSGLGEATVYALLEKGVR-VFIADRNEEKG----LQIQTKYGQDRCRFQKCDV 62
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------------YKKAIEVNVTA 350
+DE +++A V G I +++N+A +++ + + + + VNV
Sbjct: 63 SDEAQVKALVDACVATFGAIHILLNSAGVISAGLIVGGKNQDQTIKTEEMNRVLGVNVVG 122
Query: 351 LITST----LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518
T L+ ++ + + G ++NV+SVA + +Y A+K A++ + +
Sbjct: 123 TFNVTKYVALQMVKQQPLNEFKERGVIVNVASVAGIEGQRGQTVYAASKGAIIGMTLPLA 182
Query: 519 RPEHFSKTGVRVLTVCFGATDTAL 590
R K GVRV T+ G T +
Sbjct: 183 R--DLGKFGVRVCTIAPGIFQTPM 204
>UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular
organisms|Rep: Oxidoreductase - Halobacterium salinarium
(Halobacterium halobium)
Length = 260
Score = 71.7 bits (168), Expect = 1e-11
Identities = 58/200 (29%), Positives = 91/200 (45%), Gaps = 6/200 (3%)
Frame = +3
Query: 15 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194
HE V +TGA++GIGE+ L EG + A+E +L + G+
Sbjct: 16 HELAGDVAIVTGASSGIGEATAEALAAEGAHVVLAARRADELA-ALADRIEDTDGDAL-V 73
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALI 356
+D+TD++ +++ V E G ID+++NNA +M ++ +EVN+ L+
Sbjct: 74 VPTDITDDDAIDDLVSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLM 133
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
T + IM G V+NVSSVA Y ATK V F++ I + +
Sbjct: 134 NLTHAVVPIMQDQDAGH---VVNVSSVAGRQADADSSGYNATKFGVNAFTDAI--RQELT 188
Query: 537 KTGVRVLTVCFGATDTALLT 596
+R + GA DT L T
Sbjct: 189 SQDIRTTIIEPGAVDTELST 208
>UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1;
Natronomonas pharaonis DSM 2160|Rep: Probable
dehydrogenase/ reductase 4 - Natronomonas pharaonis
(strain DSM 2160 / ATCC 35678)
Length = 253
Score = 71.7 bits (168), Expect = 1e-11
Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
+++ VFITGA +GIG + + EG +A DI E+ G+ V+ G F+
Sbjct: 3 FENDTVFITGAGSGIGRATALKVAREGAFVVAT-DINEDGGRET-VDAVEDAGGDAAFHE 60
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---GIYKKAIEVNVTALITSTLK 371
DVTD + F ++ E G +D +INNA + + + + E + +
Sbjct: 61 LDVTDADEFKAVVETAADEYG-LDAMINNAGVGHPPAYTEDVTETTFEYVLDVNLRGVWN 119
Query: 372 AIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
+ H +G G ++NV S+A+ +Y TK AVL + I + GV
Sbjct: 120 GCQAALPHLKSQGEGAIVNVGSLASFLGLPKQAVYSLTKGAVLNLTRAIA--SEAGRDGV 177
Query: 549 RVLTVCFGATDTAL 590
R VC G +T L
Sbjct: 178 RANAVCPGFIETPL 191
>UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34;
Proteobacteria|Rep: Acetoacetyl-CoA reductase -
Acinetobacter sp. (strain RA3849)
Length = 248
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/197 (25%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+ KV +TGA GIG + R L+ G K IA + EE + ++ + +F +
Sbjct: 3 EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 365
D+ + E + + +G +DV++NNA + D S + + I+ N+ L T T
Sbjct: 63 DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ K K G ++N+SSV L Y A+K+ ++ F+ + + +++
Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177
Query: 546 VRVLTVCFGATDTALLT 596
+ V V G T T ++T
Sbjct: 178 ICVNVVAPGYTATPMVT 194
>UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59;
cellular organisms|Rep: Acetoin(diacetyl) reductase -
Klebsiella pneumoniae
Length = 256
Score = 71.7 bits (168), Expect = 1e-11
Identities = 54/193 (27%), Positives = 88/193 (45%), Gaps = 6/193 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGA GIG+++ L+ +G +AI D + K++ E+N G + + DV
Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 371
+D + + + GG DV++NNA + +SI I K +NV +I
Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A+E K G GG +IN S A + + +Y ++K AV + R + G+
Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176
Query: 552 VLTVCFGATDTAL 590
V C G T +
Sbjct: 177 VNGYCPGIVKTPM 189
>UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii
KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
KSM-K16)
Length = 247
Score = 71.3 bits (167), Expect = 2e-11
Identities = 61/207 (29%), Positives = 100/207 (48%), Gaps = 7/207 (3%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E +KVV ITG A+GIG + V L +G K + I D +E G++ EL G + F
Sbjct: 3 ELTNKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFV 60
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALIT 359
++DV++E ++ V+ +D++INNA M+ S Y+K ++V +
Sbjct: 61 QTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFL 120
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
+ AI+ M K GG +IN SS+ ++ Q +P Y A K AV + + ++
Sbjct: 121 GSKHAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYA 174
Query: 537 KTGVRVLTVCFGATDTALLTRRETRHF 617
+RV V G +TA + + F
Sbjct: 175 DKQIRVNAVAPGFVETAAVNKEALGDF 201
>UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase,
putative; n=25; Alphaproteobacteria|Rep:
20-beta-hydroxysteroid dehydrogenase, putative -
Silicibacter pomeroyi
Length = 250
Score = 71.3 bits (167), Expect = 2e-11
Identities = 57/197 (28%), Positives = 91/197 (46%), Gaps = 8/197 (4%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K K V ITGA+ GIG R+ G ++ +L + EA + E+ G++
Sbjct: 5 KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 359
DV D G +NA V GG+DV+INNA ++ +D +G + AI++N+ +
Sbjct: 60 DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
A+ +M K GGT++ VSS AA Y A+K+ + C+ E
Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173
Query: 540 TGVRVLTVCFGATDTAL 590
G+R + + G T +
Sbjct: 174 HGIRAMGLSPGTVATQM 190
>UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Acidobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Acidobacteria bacterium
(strain Ellin345)
Length = 257
Score = 71.3 bits (167), Expect = 2e-11
Identities = 53/192 (27%), Positives = 92/192 (47%), Gaps = 3/192 (1%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV + G TGIG ++ L D G ++ E+ + E+ + G +T SDV
Sbjct: 10 KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAAAD-EIERR-GRQTLRVCSDV 67
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 383
T + NAV+ + +D+++N A + + E N + +T L+A ++
Sbjct: 68 TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127
Query: 384 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
GKH +G G +IN++S+++ H + Y A+K+A+L + + +SK GV V
Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185
Query: 561 VCFGATDTALLT 596
+ G TAL T
Sbjct: 186 IAPGVFRTALNT 197
>UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 286
Score = 71.3 bits (167), Expect = 2e-11
Identities = 48/181 (26%), Positives = 88/181 (48%), Gaps = 6/181 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+ F+TG GIG ++ I L E ++AILDI E + + G + + +DV
Sbjct: 10 QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 371
+ + ++ G +D+++NNA + S +K I++N+ +++ +T
Sbjct: 68 MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A M +GGKGG++INV+S+ A + +Y A K+ + F+ + S G+R
Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183
Query: 552 V 554
V
Sbjct: 184 V 184
>UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Mesorhizobium sp. BNC1|Rep: Short-chain
dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
BNC1)
Length = 260
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/199 (29%), Positives = 93/199 (46%), Gaps = 8/199 (4%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+K+ FITGAA GIG + EG K + + DI E+ G+ + ++ S G F R D
Sbjct: 5 NKIAFITGAAEGIGACAAGLFSREGAK-VILSDIDEDRGRKVADQVTSA-GGDAVFVRCD 62
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTALITS 362
VT E AV + G + ++ NN + + + + A+++NV +++
Sbjct: 63 VTSEASVREAAAAVQERYGALHILYNNVGGSTPRDDRVTDVDLEEFWSAMKLNVLSVVLP 122
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
I ++ SG GG+VIN +S AL + Y A+K AV+ + + F
Sbjct: 123 ARHLIPLIAA-SG--GGSVINTASYMALLGTAGRDCYTASKGAVVSLTRSMA--VEFGPD 177
Query: 543 GVRVLTVCFGATDTALLTR 599
+RV + GA DT L R
Sbjct: 178 NIRVNVIGPGAVDTERLRR 196
>UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Gammaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Marinomonas sp. MWYL1
Length = 256
Score = 71.3 bits (167), Expect = 2e-11
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
KD+ VFI+G ATGIG ++V +G K A +D+ E+AG +L L +K G +F
Sbjct: 13 KDRSVFISGGATGIGAAIVEAYAKQGAK-TAFVDLDEKAGTALAKRL-TKDGYDVRFEVC 70
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 371
D+TD + + + A + G I V++NNAA ND + E L+ +K
Sbjct: 71 DITDIQDYQSKIRAAAEVFGPITVLLNNAA--NDVRHSLESLTEERFDELVGVNIKHAMF 128
Query: 372 ---AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
A+ M + G GG++IN SV + + P Y +K+A + + R
Sbjct: 129 AAQAVAPMMRKLG--GGSIINFGSVGWMMATAGYPTYGTSKAATHGLTRSLAR--DLGGF 184
Query: 543 GVRVLTVCFG 572
G+RV T+ G
Sbjct: 185 GIRVNTLVPG 194
>UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Sphingomonadaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 261
Score = 71.3 bits (167), Expect = 2e-11
Identities = 52/201 (25%), Positives = 99/201 (49%), Gaps = 8/201 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS + KV +TG + GIG + R+L G + I E+ ++ + E+ +K G K
Sbjct: 1 MSQDMTGKVAIVTGGSDGIGLATARLLAARGAT-VVICARREDKLEAARAEI-AKVG-KV 57
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA 350
+ + DV+DE F ++ V G +D+++NNA ++ + + ++K VN A
Sbjct: 58 EAVKLDVSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADA 117
Query: 351 LITSTLKAIEIMG--KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
+ T A+++M + G + G ++N++S + + M Y A+K+A++ F+
Sbjct: 118 VFVGTKAAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAM- 176
Query: 525 EHFSKTGVRVLTVCFGATDTA 587
+ G+RV + G TA
Sbjct: 177 -EGAPLGIRVNAIVPGQVMTA 196
>UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1;
Flavobacteriales bacterium HTCC2170|Rep: Probable
glucose 1-dehydrogenase - Flavobacteriales bacterium
HTCC2170
Length = 268
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 5/194 (2%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K K V +TG + GIG + R L G + + E++ + L E+++ YG +T +
Sbjct: 7 KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
DV+ E + + GGID+++NNA +SI +E +I LK +
Sbjct: 67 DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124
Query: 384 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
K +G + GG +IN+SS+ + + Y + K+ + S C+ ++ +
Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182
Query: 549 RVLTVCFGATDTAL 590
RV++V GA T +
Sbjct: 183 RVVSVAPGAISTEM 196
>UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=9; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 259
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/203 (27%), Positives = 94/203 (46%), Gaps = 8/203 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M+ + +V ITG +GIG + V+ + EG K + I DI + G L +L +
Sbjct: 1 MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVA 57
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNV 344
+ DVT +E + G +D+ NNA ++++ + ++K EVN+
Sbjct: 58 TYVHVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNL 117
Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
T++ A+ M + G+G + S VA + + Y A+K VL + +G
Sbjct: 118 TSVYLCCKAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG-- 173
Query: 525 EHFSKTGVRVLTVCFGATDTALL 593
F++ GVRV +C G +T LL
Sbjct: 174 VQFARQGVRVNALCPGPVNTPLL 196
>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Nocardioides sp. (strain BAA-499 / JS614)
Length = 253
Score = 71.3 bits (167), Expect = 2e-11
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 5/196 (2%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
++ KVV ITG ATGIG + +G + + + D+ + A ++ V L + G F
Sbjct: 6 DFTGKVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAET--VRLIEESGGTALFV 62
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
R+DVT ++ V GG+ V NNA ++ + G + E + I LK +
Sbjct: 63 RTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGV 121
Query: 378 EIMGKH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ K+ + GG++IN +SVA + M Y A K V+ + ++
Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAA 179
Query: 543 GVRVLTVCFGATDTAL 590
GVRV + G DT +
Sbjct: 180 GVRVNALAPGLVDTPM 195
>UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2;
Gammaproteobacteria|Rep: Short chain dehydrogenase -
marine gamma proteobacterium HTCC2080
Length = 291
Score = 71.3 bits (167), Expect = 2e-11
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K + ITGAA+G+G ++ + EG + I DI +E G + +LN +Y N F ++
Sbjct: 2 KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 383
T + + ++ + + G+D ++NNA + + I + K + V + +K +
Sbjct: 61 TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120
Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
G +INV+S+A L M Y +K+ ++ FS G GV+V V
Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178
Query: 564 C 566
C
Sbjct: 179 C 179
>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
family member 10 - Homo sapiens (Human)
Length = 270
Score = 71.3 bits (167), Expect = 2e-11
Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 369 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176
Query: 546 VRVLTVCFGATDTAL 590
VRV + G T L
Sbjct: 177 VRVNCISPGNIWTPL 191
>UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate
dehydrogenase; n=31; Bacteria|Rep:
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase -
Bacillus subtilis
Length = 261
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 3/188 (1%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K+ FITGAA GIGE+V R L +G HIA +D E + + L ++ + + +DV
Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYKKAIEVNVTALITSTLKAIEI 383
D I + +E G ID+++N A ++ + + + E + T A
Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126
Query: 384 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
+ K+ + G+++ V S A M Y ++K+A + F+ C+G ++ +R
Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL--ELAEYNIRCNI 184
Query: 561 VCFGATDT 584
V G+T+T
Sbjct: 185 VSPGSTET 192
>UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep:
Bll5898 protein - Bradyrhizobium japonicum
Length = 256
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/201 (30%), Positives = 92/201 (45%), Gaps = 7/201 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M +KDKVV +TGA +GIG + R EG I +L+ E S E+ ++ G
Sbjct: 1 MLSRFKDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDR 55
Query: 189 KFYR-SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVT 347
R +DVT ++ V+ G ID+++NNA + I ++ VNV
Sbjct: 56 CMIRPADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVD 115
Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
++ T A+ H GG+++NVSS++ L + Y ATK AV + +
Sbjct: 116 GVLYMTRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL-- 169
Query: 528 HFSKTGVRVLTVCFGATDTAL 590
F GVR+ VC T T L
Sbjct: 170 EFGPRGVRINAVCPSLTLTHL 190
>UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep:
Oxido-reductase - Serratia marcescens
Length = 254
Score = 70.9 bits (166), Expect = 2e-11
Identities = 60/203 (29%), Positives = 94/203 (46%), Gaps = 8/203 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K VFITGA GIG + L+ G I ++E+G V L G K + +D+
Sbjct: 7 KKVFITGAEQGIGRATAERLIKAGCD-IYFHYHSDESGPKALVALAHSLGQKAAYGYADL 65
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
D + L ++A + GGID++INN L ++ I+VN+T ++ T
Sbjct: 66 IDTDETLRCVSAGAEFLGGIDILINNVGGIVGRKWLGEIDRAFWQTVIDVNMTTMLNVTQ 125
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A+ + + G ++IN++S+A H +Y ATK AVL ++ + + G
Sbjct: 126 SALPHL--KAAPNGASIINLASLAGRAGGHAGSLVYSATKGAVLTWTRSLA--AELGEHG 181
Query: 546 VRVLTVCFGATDTALLTRRETRH 614
+RV V A L TR RH
Sbjct: 182 IRVNAV---APGLILGTRFHNRH 201
>UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Polaromonas sp. JS666|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 265
Score = 70.9 bits (166), Expect = 2e-11
Identities = 54/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE-AGKSLQVELNSKYGNK 185
M + K+K V +TG + IG ++V EG HI I D+ E+ A K+ ++ L S +
Sbjct: 1 MDIDLKNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKTAELALLSGAAS- 58
Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVT 347
+ ++DVT + + A V + GG+DV++NN LM + +++K I +N
Sbjct: 59 AQVVKTDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYV 118
Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
++ T A+++M + G+++++SS A+ +Y K+A+ F I +
Sbjct: 119 GVLNCTKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN 175
Query: 528 HFSKTGVRVLTVCFGAT 578
+ G+R VC G T
Sbjct: 176 --GRYGIRCNVVCPGIT 190
>UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caulobacter sp. K31|Rep: Short-chain
dehydrogenase/reductase SDR - Caulobacter sp. K31
Length = 254
Score = 70.9 bits (166), Expect = 2e-11
Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
Frame = +3
Query: 3 LNMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
++++ K KV ITGAA G+GE++ R + G + I D+ E G+++ ++ ++ G
Sbjct: 1 MSVNDSLKGKVAIITGAAQGLGEAIAREFVARGAA-VIITDVQREEGEAVAADILAQ-GG 58
Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNV 344
K F DV D E + ++ + G +DV++NNA L+ + I ++ + VNV
Sbjct: 59 KALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNV 118
Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGR 521
KAI K +G GG +IN+SS+ + Q+ + Y +K AV + +
Sbjct: 119 RGPWLG-CKAILPALKAAG--GGAIINMSSMNGMIAQNPGLSAYATSKGAVRMLTKAVA- 174
Query: 522 PEHFSKTGVRVLTV 563
+ + + GVRV +V
Sbjct: 175 -QDYVQYGVRVNSV 187
>UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2;
Bacteria|Rep: Cyclopentanol dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 355
Score = 70.9 bits (166), Expect = 2e-11
Identities = 57/194 (29%), Positives = 92/194 (47%), Gaps = 6/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITG A G GE+ R+ G H+ I D+ EE G+ L EL G + F DV
Sbjct: 102 KVALITGGARGQGEAEARLFAQHGA-HVYICDVLEEEGEKLAAELRGS-GLQADFRFLDV 159
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIG-IYKKAIEVNVTALITSTLK 371
TD E + + + G +DV+INNA + + D+ + + + VN + ++
Sbjct: 160 TDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG-MQ 218
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A + K SG G++IN+ S A + H + Y A+K AV + + +G+R
Sbjct: 219 ACAPLMKRSG--NGSIINIGSTAGI-MGHPVAAYSASKWAVRGLTKAAAM--ELASSGIR 273
Query: 552 VLTVCFGATDTALL 593
V + G +T ++
Sbjct: 274 VNAMHPGVVETPMV 287
>UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1;
Mycobacterium ulcerans Agy99|Rep: Short-chain
dehydrogenase - Mycobacterium ulcerans (strain Agy99)
Length = 282
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/191 (28%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
+VV ITGA +GIG + + G +A+ DI + A + +G+ R DV
Sbjct: 16 RVVAITGAGSGIGRELALLCAQRGAD-LALCDINDTAVADT-AQTARGFGHDVITRRVDV 73
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAIE- 380
+D E +A + GG+D+++NNA L+ + +K + V+ + + E
Sbjct: 74 SDPEQMTAFADATLGHFGGVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEA 133
Query: 381 -IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
+ G+GG V+N+SS A L + + Y ATK AVL S + R E + V
Sbjct: 134 FLPAMIESGRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEAL-RIE-LEPHRIGVT 191
Query: 558 TVCFGATDTAL 590
+C G +TA+
Sbjct: 192 AICPGVINTAI 202
>UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Rep:
RH03309p - Drosophila melanogaster (Fruit fly)
Length = 247
Score = 70.9 bits (166), Expect = 2e-11
Identities = 52/204 (25%), Positives = 99/204 (48%), Gaps = 13/204 (6%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
W + V +TGA++GIG ++ R L+ GV +A+ + + L+ EL ++ + +
Sbjct: 4 WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRL-EQLREELPQDRRSRLRIMQ 62
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362
DV+D + +AV + G +D++INNA L+ S+ ++ ++ NV ++
Sbjct: 63 CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 122
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP-------IYFATKSAVLQFSNCIGR 521
T +A E M + G V+ ++S+ + +P +Y ATK A+ + +
Sbjct: 123 TQRAFESMRQRQ--SKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ 180
Query: 522 PEHFSKTGVRVLTVCFGATDTALL 593
KT V+V ++ G DT L+
Sbjct: 181 EMRDFKTKVKVTSISPGLVDTELV 204
>UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 70.9 bits (166), Expect = 2e-11
Identities = 60/199 (30%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYR 200
DKV ITG++ GIG++ R+L EG K AE E K++ + GN
Sbjct: 6 DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 350
D+T E ++ + + + G ID+++NNA +N SI Y K E+NV +
Sbjct: 65 GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPE 527
+I T KA H G ++N+SS+ A + V P Y K+A+ Q++
Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178
Query: 528 HFSKTGVRVLTVCFGATDT 584
G+RV +V GA T
Sbjct: 179 DLVPEGIRVNSVSPGAVST 197
>UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
dehydrogenase/reductase SDR - Methanospirillum hungatei
(strain JF-1 / DSM 864)
Length = 274
Score = 70.9 bits (166), Expect = 2e-11
Identities = 57/205 (27%), Positives = 100/205 (48%), Gaps = 6/205 (2%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
MS ++ KV +TG +GIG +V LL G I E K+ + + Y N T
Sbjct: 1 MSDVFEGKVAIVTGGTSGIGYAVSEELLKRGATVWVIGSRQESVDKARKSF--AAYKN-T 57
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MND-----SIGIYKKAIEVNVTA 350
+F DVT + G+++A V++ G +D + NNA + M ++ ++++AI++N+
Sbjct: 58 RFLAVDVTVADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWG 117
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
++ A+ +M K G ++N SS+A + Y ATK AV + + R E
Sbjct: 118 VVYGVHFALPVM---LAQKSGHIVNTSSIAGIVPLPSQAAYCATKHAVTALTESL-RYEF 173
Query: 531 FSKTGVRVLTVCFGATDTALLTRRE 605
F + G+ T+C TA+ + +
Sbjct: 174 FEE-GIAFTTICPSNVATAIFGKAD 197
>UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein)
reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl
carrier protein) reductase - Geobacter sulfurreducens
Length = 246
Score = 70.5 bits (165), Expect = 3e-11
Identities = 53/197 (26%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = +3
Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
E+KD +V +TG GIG ++ +G A +EA ++L+ E G+
Sbjct: 2 EFKDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVI 60
Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
R+DV E + +++A E G + V++NNA ++ D G E + A++ + L +
Sbjct: 61 RADVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPL 118
Query: 378 EI-----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ K + G +IN+SSV+A + Y ATK A + F+ + R
Sbjct: 119 FHCCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPL 176
Query: 543 GVRVLTVCFGATDTALL 593
G+RV V G +T ++
Sbjct: 177 GIRVNAVAPGLIETEMI 193
>UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
dehydrogenase; n=25; Proteobacteria|Rep:
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
Burkholderia mallei (Pseudomonas mallei)
Length = 265
Score = 70.5 bits (165), Expect = 3e-11
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 8/170 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG-KSLQVELNSKYGNKTKFYR-S 203
K FITGAA G+G ++ R + ++G + + + DI + A ++ ELN G + +
Sbjct: 14 KRAFITGAAGGLGRAIARRMAEQGAQ-VFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQ 72
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-DSIG-----IYKKAIEVNVTALITST 365
DV DE + L+ GG+ V+++NA + + +IG +++ + +NV +++ T
Sbjct: 73 DVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGT 132
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515
A+ + G +++N+SSVAA Q Y A+K+AV + I
Sbjct: 133 KHALPYL---EAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSI 179
>UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like
protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Short-chain alcohol dehydrogenase-like protein - Hahella
chejuensis (strain KCTC 2396)
Length = 288
Score = 70.5 bits (165), Expect = 3e-11
Identities = 53/198 (26%), Positives = 94/198 (47%), Gaps = 6/198 (3%)
Frame = +3
Query: 15 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194
H + +K V ITGAA+G+G + R L G + +A D+ +E G ++ L N+ +
Sbjct: 2 HRFPEKRVAITGAASGLGLATARHFLSRGWR-VAFADVQDETGSAIVASLGLP-ENRAFY 59
Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG-----IYKKAIEVNVTALI 356
DVT +V+ GG+D++INNA + + IG ++ I++++ ++
Sbjct: 60 QHVDVTKVRDIQAWRRKIVETWGGLDILINNAGVAAHGGIGEAPLEDWEWVIDIDLMGVV 119
Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
+ + + + G ++N++S+A L + M Y A K+ V+ S + S
Sbjct: 120 RGCKEFAPLFKRQ---RSGQIVNIASMAGLVHAPEMGSYNAAKAGVVALSETL--VGELS 174
Query: 537 KTGVRVLTVCFGATDTAL 590
GV V VC G T L
Sbjct: 175 PFGVGVNVVCPGFFSTGL 192
>UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase
precursor; n=2; Clostridium difficile|Rep: Probable
short chain dehydrogenase precursor - Clostridium
difficile (strain 630)
Length = 245
Score = 70.5 bits (165), Expect = 3e-11
Identities = 46/197 (23%), Positives = 96/197 (48%), Gaps = 6/197 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
K K V ITG A GIG+++ + EG + + +E K L LN K K +++
Sbjct: 2 KKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEK-NFSVKLFKA 60
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365
++++ E +++ ++E GG+DV++NNA + D + + + +N+ +
Sbjct: 61 NISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMMNINLKGSFYCS 120
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
A++ M K G +IN+SS+ ++ + Y TK+ ++ + + + +
Sbjct: 121 QVALKYM---ISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK--EVGPSN 175
Query: 546 VRVLTVCFGATDTALLT 596
+RV ++ G +T +L+
Sbjct: 176 IRVNSIAPGVINTDMLS 192
>UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=3;
Proteobacteria|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family protein - Erythrobacter
sp. NAP1
Length = 267
Score = 70.5 bits (165), Expect = 3e-11
Identities = 53/182 (29%), Positives = 90/182 (49%), Gaps = 7/182 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
K V ITG++ GIGE + R EG + AE+ K L++ ++T DV
Sbjct: 10 KTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADT-LDA---DRTLTCPGDV 65
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITSTL 368
+ + I+ V+ GG+D ++NNA + S+ ++K + I++NV +I
Sbjct: 66 SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSM-LHKTDDEEIDRIIDINVKGVIYLCR 124
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
AI + K GG++IN+SSV+ + ++PIY A+K A+ + G + G+
Sbjct: 125 AAIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTR--GLAQQIGGMGI 182
Query: 549 RV 554
RV
Sbjct: 183 RV 184
>UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:
Acetoin reductases - Mycobacterium sp. (strain KMS)
Length = 285
Score = 70.5 bits (165), Expect = 3e-11
Identities = 55/203 (27%), Positives = 93/203 (45%), Gaps = 9/203 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV +TGA GIG + L +G IA++D++E E+ S+ G+KT + +DV
Sbjct: 27 KVALVTGAGRGIGRGIAVELARQGAD-IALVDVSEAGLPDAAAEI-SEIGSKTTTFVADV 84
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAI----EVNVTAL---ITS 362
D + ++ GG DV++NNA AL+ + + + +NV + I +
Sbjct: 85 RDRDAVFAAVDHAAAALGGFDVMVNNAGIALVGPIAEVTAEDLARLWAINVDGVLWGIQA 144
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
+ +G H+ GK +IN SS+A ++ Y ATK AV + + ++
Sbjct: 145 AAAKFKELGNHAEGKVSKIINASSIAGHEGFAMLGPYSATKFAVRALTQAAAK--EYAAD 202
Query: 543 GVRVLTVCFGATDTALLTRRETR 611
G+ V C G T + + R
Sbjct: 203 GITVNAYCPGVVGTDMWVEIDKR 225
>UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=6; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Paracoccus
denitrificans (strain Pd 1222)
Length = 253
Score = 70.5 bits (165), Expect = 3e-11
Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 7/195 (3%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
M KDKVV ITGA GIG + ++ ++EG + + + D +A + + EL G
Sbjct: 1 MDMHLKDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENA 55
Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
+ + DV+ E +++ V E GG+DV++NNA + ++ I+VN+T
Sbjct: 56 RAFTVDVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTG 115
Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCIGRPE 527
+ + A+ + K GG ++N +S A+ + Y A K V + +
Sbjct: 116 VYLCSKYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL-- 170
Query: 528 HFSKTGVRVLTVCFG 572
F+ +RV +V G
Sbjct: 171 DFAADNIRVNSVAPG 185
>UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; unclassified Gammaproteobacteria
(miscellaneous)|Rep: Short-chain dehydrogenase/reductase
SDR - marine gamma proteobacterium HTCC2080
Length = 297
Score = 70.5 bits (165), Expect = 3e-11
Identities = 56/209 (26%), Positives = 99/209 (47%), Gaps = 7/209 (3%)
Frame = +3
Query: 6 NMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185
N + +++ K I+G A GIG S+ + L ++ + ++ + DI ++ + ++EL S G
Sbjct: 5 NSTSQFQGKTAIISGGAEGIGLSIAKALGEQQM-NVVLADIDKDNLERARLELQS-LGVP 62
Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNV 344
DV DE + A V+ G I +V+NNA + DS I ++ A++VN+
Sbjct: 63 VLAVSLDVADEGQWQLAAEAAVERFGKIHMVVNNAGVGGDSGPIESQEKEGWQWALDVNL 122
Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
++ + ++ +H G+GG +INV+S+A + Y ATK+AV+ S
Sbjct: 123 MGVVYGAKVVVPLIKEH--GEGGWIINVASMAGMGGVPYSGAYNATKAAVVALSEAWS-- 178
Query: 525 EHFSKTGVRVLTVCFGATDTALLTRRETR 611
E V V +C T + R
Sbjct: 179 EELKSKSVHVAVLCPAFVQTRIYDSERNR 207
>UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3;
Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 -
Eubacterium sp. (strain VPI 12708)
Length = 249
Score = 70.5 bits (165), Expect = 3e-11
Identities = 49/194 (25%), Positives = 91/194 (46%), Gaps = 7/194 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 200
+DK+ ITG GIG + ++ ++ G K ++I +E + +L Y + +
Sbjct: 5 QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362
D+T + + + V Q+ G +DV+INNA + +S+ +K +++NV +
Sbjct: 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
A + M K G +IN +SV + S Y +K+ V+ ++ +GR +
Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178
Query: 543 GVRVLTVCFGATDT 584
+RV+ V G DT
Sbjct: 179 NIRVVGVAPGVVDT 192
>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 254
Score = 70.1 bits (164), Expect = 4e-11
Identities = 59/195 (30%), Positives = 92/195 (47%), Gaps = 7/195 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KVV ITG A GIG++ ++LLD G K +A++DI E++ + L+ + ++ +V
Sbjct: 4 KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
T EE + V G IDV NNA + I ++K + +NVT +
Sbjct: 62 TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121
Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
++ M K G+++N +S AA S M Y A+K AV + + G+
Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176
Query: 549 RVLTVCFGATDTALL 593
RV V A DT +L
Sbjct: 177 RVNAVAPAAIDTQML 191
>UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: FabG protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 248
Score = 70.1 bits (164), Expect = 4e-11
Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 6/201 (2%)
Frame = +3
Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
++ K +TGA TGIG+++ L EG K + + K+LQ E + + N +
Sbjct: 4 FEQKTALVTGAGTGIGQAIAVRLAQEGAKVL----VVGRTEKTLQ-ETTALHPN-IAYAV 57
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362
+D+ ++ I+ + Q+ GG+D++INNA + I Y K +NV AL+
Sbjct: 58 ADIEKDDDVQKIVQQLNQKYGGLDILINNAGWAPVTPISQVKIEEYDKVFGINVRALVNL 117
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
TL+ + ++ + G +IN+SS M +Y TK+AV F+ +
Sbjct: 118 TLQCLPML----KARKGNIINMSSAICRNHLPNMSMYAGTKAAVEIFTKIWAK--ELGAD 171
Query: 543 GVRVLTVCFGATDTALLTRRE 605
GVRV ++ G +T + + +
Sbjct: 172 GVRVNSISVGPIETPIYDKTD 192
>UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=6; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 249
Score = 70.1 bits (164), Expect = 4e-11
Identities = 56/193 (29%), Positives = 90/193 (46%), Gaps = 5/193 (2%)
Frame = +3
Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
V +TGA TGIG + +G ++ + EEAG+SL EL + G K +F ++DV +
Sbjct: 6 VLVTGALTGIGRATAIAFAKQGA-NVVVSGRREEAGQSLAAELRT-LGAKAEFIKADVAN 63
Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 395
E ++ V G +D+ INNA ++G + NV A ++ + + KH
Sbjct: 64 EAEVRSLVEKAVSLFGQLDIAINNAG-TEGALGPITEQSTENVHATFSTNVLGTLLSMKH 122
Query: 396 S----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
+G G+++N+SS+A +Y A+K AV + + GVRV
Sbjct: 123 EIRAMQAQGHGSIVNLSSIAGKVGMAGASVYVASKHAVEGLTKSAAL--EGAAFGVRVNA 180
Query: 561 VCFGATDTALLTR 599
V G T +L R
Sbjct: 181 VAPGPVQTDMLDR 193
>UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4;
Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase
- Clostridium perfringens (strain SM101 / Type A)
Length = 253
Score = 70.1 bits (164), Expect = 4e-11
Identities = 62/201 (30%), Positives = 95/201 (47%), Gaps = 10/201 (4%)
Frame = +3
Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
+S K+KVV +TG GIG + V+ LD G K +A+ +E ELN N
Sbjct: 4 LSKSIKNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYD 62
Query: 189 KF-YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNV 344
+ ++ D +++ V+++ G ID++INNA ++D+ IY K I++NV
Sbjct: 63 AIGFYPNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINV 121
Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
A+ T EIM K G ++N SSV +L Y +K AV + + R
Sbjct: 122 KAIFNCTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR- 177
Query: 525 EHFSKTGVRVLTVCFG--ATD 581
+ G+RV V G ATD
Sbjct: 178 -ELGRDGIRVNAVAPGIIATD 197
>UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 276
Score = 70.1 bits (164), Expect = 4e-11
Identities = 50/198 (25%), Positives = 95/198 (47%), Gaps = 7/198 (3%)
Frame = +3
Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
+K++ +TGA +GIG +V EG +A+ EE G ++ V + G K +F + D
Sbjct: 13 EKIMLVTGATSGIGRAVAIRAAKEGATVVAV-GRNEERGAAV-VAAMEEAGGKGEFMKCD 70
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 365
V++++ + + ++ G +DV +NNA ++ S + + + I+ N+ +
Sbjct: 71 VSNKDAVKALFAEIQEKYGKLDVAVNNAGIVGASKTVEELEDDDWFQVIDANLNSCFFCC 130
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+ +++M GG ++NVSSVA + Y A+K AV + + ++ G
Sbjct: 131 REEVKLMQP----SGGAIVNVSSVAGMRGFPSAAAYVASKHAVSGLTKAVA--VDYATKG 184
Query: 546 VRVLTVCFGATDTALLTR 599
+ +C TDT L R
Sbjct: 185 ITCNAICPAGTDTPLTER 202
>UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain
dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
Length = 273
Score = 70.1 bits (164), Expect = 4e-11
Identities = 58/200 (29%), Positives = 98/200 (49%), Gaps = 10/200 (5%)
Frame = +3
Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY---GNKTKFYRSDVT 212
+TGAA+GIG ++ LL + + DI EA Q+ N K G + DV
Sbjct: 7 VTGAASGIGRALCERLLTDKGNQVCACDINYEA--LTQIYANHKLADAGGSLILRQLDVR 64
Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLK 371
D + + ++N V+ + IDV+ N A ++ D+ I + ++NV I T
Sbjct: 65 DVQQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQS 124
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
++ M ++ G G +INV+S+AAL+ + +Y A+K AV +S G K G+
Sbjct: 125 VVDTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIA 179
Query: 552 VLTVCFGATDTALLTRRETR 611
V T+C A T +L +++ +
Sbjct: 180 VTTLCPDAVQTPMLDQQKDK 199
>UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Sphingomonas wittichii RW1|Rep: Short-chain
dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
Length = 264
Score = 70.1 bits (164), Expect = 4e-11
Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITG TGIG ++ R+ +G + ++A EA + VE G D+
Sbjct: 5 KVAIITGGGTGIGAAIARLFARKGAHVVITSELAAEAMAPV-VEAIRADGGSASAMSCDI 63
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIE----VNVTALITSTLK 371
D ++ V ++ G ID++I +A + + + I+ VNV I+
Sbjct: 64 MDRAAIAALVEGVERDHGRIDILIQSAGVCFAGPIETMEPRKIDLTFGVNVIGAISMIQA 123
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
A+ M K +GG G ++N+SS AA+ + M +Y A+K+A+ F+ + PE +T +R
Sbjct: 124 ALPAM-KRAGG--GAIVNISSGAAVLGVNEMAVYAASKAAIAHFTRTLA-PE-LRRTNIR 178
Query: 552 VLTVCFGATDTALL 593
+ + G+ T +L
Sbjct: 179 INAIGPGSVRTQML 192
>UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;
n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
FadB2x - Pseudomonas stutzeri (strain A1501)
Length = 258
Score = 70.1 bits (164), Expect = 4e-11
Identities = 62/204 (30%), Positives = 92/204 (45%), Gaps = 14/204 (6%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+DKVV ITG A+G+G + L E IAI D+ EAG+ L ++ + F +
Sbjct: 4 QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 350
DV+ EE ++AV+ G I V IN AA+ + + +A +N+
Sbjct: 61 DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120
Query: 351 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
+ K E M K+ +G + G VINVSS AA Y ATK+ V+ + R
Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180
Query: 522 PEHFSKTGVRVLTVCFGATDTALL 593
GVRV + G T ++
Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMV 202
>UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family protein; n=1;
Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain
dehydrogenase/reductase family protein - Algoriphagus
sp. PR1
Length = 265
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/181 (26%), Positives = 94/181 (51%), Gaps = 6/181 (3%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV+ +TG+ TGIG+++ + ++ EG K + I + E+ G+ + EL + + K + D+
Sbjct: 6 KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 371
++E +++ V+ G +D ++NNAA++ S + +EVN + T
Sbjct: 62 SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121
Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
AI + ++ G V+N+ S+ A + H + Y +K A++ + +G F + GVR
Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176
Query: 552 V 554
V
Sbjct: 177 V 177
>UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase
SDR - Pelobacter propionicus (strain DSM 2379)
Length = 283
Score = 70.1 bits (164), Expect = 4e-11
Identities = 53/199 (26%), Positives = 97/199 (48%), Gaps = 10/199 (5%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
KV ITGA GIG ++ L +G + + D+ + + E+ ++ G K R+DV
Sbjct: 24 KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81
Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 368
T E +++ V++ G +D+++ NA + N + I + + + VN A + T+
Sbjct: 82 TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141
Query: 369 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
A +++ + HS G GG +IN +S+AA + ++ Y A+K AV F+ + +
Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAK--ELGP 199
Query: 540 TGVRVLTVCFGATDTALLT 596
+ V C G T + T
Sbjct: 200 YKINVNAYCPGIVGTDMWT 218
>UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductase
precursor; n=8; Plasmodium|Rep: 3-oxoacyl-acyl-carrier
protein reductase precursor - Plasmodium falciparum
Length = 301
Score = 70.1 bits (164), Expect = 4e-11
Identities = 42/169 (24%), Positives = 88/169 (52%), Gaps = 3/169 (1%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
++KV +TGA GIG + + +L + V H+ + +++ S+ E+ S +G ++ Y
Sbjct: 59 ENKVALVTGAGRGIGREIAK-MLAKSVSHVICISRTQKSCDSVVDEIKS-FGYESSGYAG 116
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE---VNVTALITSTLKA 374
DV+ +E ++N ++ E +D++++NA + D++ + K E V T L +
Sbjct: 117 DVSKKEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYIT 176
Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
I + + G +IN+SS+ LT + Y ++K+ V+ F+ + +
Sbjct: 177 QPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAK 225
>UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41;
Magnoliophyta|Rep: Xanthoxin dehydrogenase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 285
Score = 70.1 bits (164), Expect = 4e-11
Identities = 57/196 (29%), Positives = 90/196 (45%), Gaps = 9/196 (4%)
Frame = +3
Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY-RSD 206
KV ITG ATGIGES+VR+ G K + I+D+ ++ G + L +T F+ D
Sbjct: 21 KVALITGGATGIGESIVRLFHKHGAK-VCIVDLQDDLGGEVCKSLLRGESKETAFFIHGD 79
Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL--------MNDSIGIYKKAIEVNVTALITS 362
V E+ ++ V+ G +D++INNA L N S+ ++ +VNV S
Sbjct: 80 VRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIRNYSLSEFEMTFDVNVKGAFLS 139
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
A +M K G+++++ SV + Y +K AVL + + +
Sbjct: 140 MKHAARVMIPE---KKGSIVSLCSVGGVVGGVGPHSYVGSKHAVLGLTRSVA--AELGQH 194
Query: 543 GVRVLTVCFGATDTAL 590
G+RV V A T L
Sbjct: 195 GIRVNCVSPYAVATKL 210
>UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep:
Gll2858 protein - Gloeobacter violaceus
Length = 268
Score = 69.7 bits (163), Expect = 5e-11
Identities = 55/200 (27%), Positives = 90/200 (45%), Gaps = 8/200 (4%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ-VELNSKYGNKTKFYR 200
++KV +TGA++GIG + L G K +A A G +L+ VE G++ F +
Sbjct: 22 ENKVAIVTGASSGIGRATALELARRGAKVVAS---ARRVGPTLELVEAIRAEGHEATFVQ 78
Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALIT 359
+DVTDE + ++ + G +D+ NNA L+ + Y + NV ++
Sbjct: 79 ADVTDEAYVERLVAEAIATYGKLDIAFNNAGTEGVFAPLLEQTKETYDLVFDANVRSVFY 138
Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
S + M GG ++N +S+ + +Y ATK AVL + + +
Sbjct: 139 SMKHQAQAM---LCAGGGVIVNNASMGGVIGFENAALYIATKHAVLGMTKSAAL--EWYR 193
Query: 540 TGVRVLTVCFGATDTALLTR 599
GVRV +C G DT R
Sbjct: 194 RGVRVNAICPGIIDTPFQDR 213
>UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 290
Score = 69.7 bits (163), Expect = 5e-11
Identities = 59/201 (29%), Positives = 92/201 (45%), Gaps = 7/201 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+D+VV +TG A+GIG + V L G + + D+ + L E+ + F R+
Sbjct: 6 EDRVVVVTGGASGIGRASVLRFLAAGAR-VVFGDVNGATAQRLLDEVADPA--RLHFERA 62
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 362
DV DE ++ A V+ G +DV+ NNA L + + + + V +
Sbjct: 63 DVADEAEVAALVAAAVERFGRLDVMFNNAGVGGAFGPLTDIDVADWDRTFGVISRGMFLG 122
Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
T A M G GG++IN SSVA + Y A K+AV+ F+ C E +
Sbjct: 123 TKHAARAMIAQGG--GGSIINNSSVAGVGGGGGPTAYSAAKAAVINFT-CNAAVE-LAAH 178
Query: 543 GVRVLTVCFGATDTALLTRRE 605
+RV +C G DT L+ R+
Sbjct: 179 RIRVNAICPGLVDTPLVMGRD 199
>UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 244
Score = 69.7 bits (163), Expect = 5e-11
Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 6/195 (3%)
Frame = +3
Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
+ K +FITGA+ GIG+S+ + G + + K L+ + KY
Sbjct: 2 EQKTIFITGASRGIGKSIALLFASRGYHTFLNCSSSVDELKKLRAYITEKYHTPCTLVPG 61
Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDSIG-IYKKAIEVNVTALITST 365
+V + +H I N + QE +DV++NNA L+ D + + I+ N++++
Sbjct: 62 NVGNPDHVRAIYNKIYQECTHLDVLVNNAGISYINLLTDMTDEDWNRIIQTNLSSVFYCC 121
Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
+AI M GK +IN+SS+ + + Y A+KS + F+ + + + +
Sbjct: 122 RQAIPPMVSKRSGK---IINISSMWGTSGASCEVAYSASKSGINGFTKALAK--ELAPSN 176
Query: 546 VRVLTVCFGATDTAL 590
V+V + G DT++
Sbjct: 177 VQVNAIACGVIDTSM 191
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 628,408,880
Number of Sequences: 1657284
Number of extensions: 12594252
Number of successful extensions: 45286
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 40967
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42698
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46466611856
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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