Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30214
(733 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VP68 Cluster: CG10512-PA, isoform A; n=5; Sophophora|... 255 7e-67
UniRef50_Q7PI68 Cluster: ENSANGP00000025275; n=5; Bilateria|Rep:... 251 1e-65
UniRef50_A7RTU3 Cluster: Predicted protein; n=5; Eumetazoa|Rep: ... 213 4e-54
UniRef50_UPI0000D568D3 Cluster: PREDICTED: similar to CG10512-PA... 206 6e-52
UniRef50_UPI00015B642F Cluster: PREDICTED: similar to ENSANGP000... 204 2e-51
UniRef50_UPI000051A408 Cluster: PREDICTED: similar to VF13D12L.3... 183 3e-45
UniRef50_Q9V0D5 Cluster: Malate dehydrogenase; n=3; Archaea|Rep:... 161 2e-38
UniRef50_Q9I7T1 Cluster: CG18808-PA; n=3; Sophophora|Rep: CG1880... 154 2e-36
UniRef50_Q2LTF1 Cluster: Malate/L-lactate dehydrogenase; n=1; Sy... 148 2e-34
UniRef50_Q4J502 Cluster: Malate/L-lactate dehydrogenase; n=5; Pr... 141 1e-32
UniRef50_Q8T901 Cluster: AT13460p; n=3; Sophophora|Rep: AT13460p... 140 2e-32
UniRef50_Q58820 Cluster: L-sulfolactate dehydrogenase (EC 1.1.1.... 140 3e-32
UniRef50_A1ZPB3 Cluster: Malate dehydrogenase; n=4; Sphingobacte... 140 4e-32
UniRef50_O34736 Cluster: Uncharacterized oxidoreductase yjmC; n=... 136 5e-31
UniRef50_A1HMI4 Cluster: Malate dehydrogenase; n=1; Thermosinus ... 132 6e-30
UniRef50_Q88T45 Cluster: Malate dehydrogenase; n=1; Lactobacillu... 129 8e-29
UniRef50_A0VVP8 Cluster: Malate dehydrogenase; n=3; Bacteria|Rep... 128 1e-28
UniRef50_Q01XF2 Cluster: Malate dehydrogenase; n=1; Solibacter u... 127 2e-28
UniRef50_Q2BFJ4 Cluster: Malate dehydrogenase; n=1; Bacillus sp.... 127 3e-28
UniRef50_A6ULS2 Cluster: Malate/L-lactate dehydrogenase; n=1; Si... 126 6e-28
UniRef50_Q88XU4 Cluster: Malate / lactate dehydrogenase; n=4; La... 125 1e-27
UniRef50_Q8NSK9 Cluster: Malate/L-lactate dehydrogenases; n=5; B... 124 2e-27
UniRef50_Q8TYB0 Cluster: L-sulfolactate dehydrogenase; n=1; Meth... 124 2e-27
UniRef50_UPI0000498ABD Cluster: malate dehydrogenase; n=1; Entam... 122 1e-26
UniRef50_Q8EMJ6 Cluster: Malate dehydrogenase; n=2; Bacillaceae|... 121 2e-26
UniRef50_Q97LJ4 Cluster: Malate dehydrogenase; n=2; Clostridium|... 120 5e-26
UniRef50_UPI0000499C46 Cluster: malate dehydrogenase; n=2; Entam... 118 1e-25
UniRef50_Q4FMG7 Cluster: Malate/L-sulfolactate dehydrogenase mul... 118 1e-25
UniRef50_Q746L8 Cluster: Dehydrogenase; n=2; Thermus thermophilu... 118 2e-25
UniRef50_A1DHT6 Cluster: Malate/L-lactate dehydrogenase, putativ... 117 3e-25
UniRef50_O27273 Cluster: L-sulfolactate dehydrogenase (EC 1.1.1.... 116 8e-25
UniRef50_Q1YDL3 Cluster: Putative malate/L-lactate dehydrogenase... 114 2e-24
UniRef50_Q28JS2 Cluster: Malate/L-lactate dehydrogenase; n=1; Ja... 112 1e-23
UniRef50_Q1YIU0 Cluster: Putative malate dehydrogenase; n=1; Aur... 112 1e-23
UniRef50_A6UCA9 Cluster: Malate/L-lactate dehydrogenase; n=2; Si... 111 1e-23
UniRef50_Q2UP42 Cluster: Malate/L-lactate dehydrogenases; n=2; A... 110 4e-23
UniRef50_Q11AU4 Cluster: Malate/L-lactate dehydrogenase; n=5; Rh... 109 5e-23
UniRef50_A6C467 Cluster: Malate dehydrogenase; n=1; Planctomyces... 109 7e-23
UniRef50_Q18X65 Cluster: Malate/L-lactate dehydrogenase; n=2; De... 108 1e-22
UniRef50_Q89GS1 Cluster: Bll6274 protein; n=2; Alphaproteobacter... 108 2e-22
UniRef50_Q11JG3 Cluster: Malate/L-lactate dehydrogenase; n=1; Me... 107 2e-22
UniRef50_Q0K2P1 Cluster: Malate/L-lactate dehydrogenase; n=4; Bu... 107 4e-22
UniRef50_P30178 Cluster: Uncharacterized oxidoreductase ybiC; n=... 107 4e-22
UniRef50_Q8FDK5 Cluster: Ureidoglycolate dehydrogenase; n=6; Ent... 105 1e-21
UniRef50_P77555 Cluster: Ureidoglycolate dehydrogenase; n=23; Ba... 105 1e-21
UniRef50_Q89D62 Cluster: Blr7581 protein; n=2; Rhizobiales|Rep: ... 104 2e-21
UniRef50_A6C4Q2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 103 3e-21
UniRef50_A4FEK8 Cluster: Malate/L-lactate dehydrogenase; n=1; Sa... 103 5e-21
UniRef50_Q07251 Cluster: L-lactate dehydrogenase; n=6; Burkholde... 103 6e-21
UniRef50_A0VU86 Cluster: Malate/L-lactate dehydrogenase; n=1; Di... 102 1e-20
UniRef50_Q0SCF8 Cluster: Possible (R)-2-hydroxyacid dehydrogenas... 100 3e-20
UniRef50_Q46VE5 Cluster: (R)-2-hydroxyacid dehydrogenase; n=6; P... 99 1e-19
UniRef50_A6C5R1 Cluster: Ureidoglycolate dehydrogenase; n=1; Pla... 97 4e-19
UniRef50_Q125D0 Cluster: Malate/L-lactate dehydrogenase; n=3; Pr... 97 5e-19
UniRef50_Q9XBD3 Cluster: Putative carboxylic acid dehydrogenase;... 96 9e-19
UniRef50_Q6D702 Cluster: Putative malate/lactate dehydrogenase; ... 95 2e-18
UniRef50_Q7CRW4 Cluster: AGR_L_3209p; n=5; Alphaproteobacteria|R... 94 3e-18
UniRef50_Q21D51 Cluster: (R)-2-hydroxyacid dehydrogenase; n=2; A... 94 4e-18
UniRef50_Q18Q95 Cluster: Malate/L-lactate dehydrogenase; n=2; De... 94 4e-18
UniRef50_A0TT61 Cluster: (R)-2-hydroxyacid dehydrogenase; n=5; B... 92 1e-17
UniRef50_A4GHI0 Cluster: Malate dehydrogenase; n=1; uncultured m... 91 3e-17
UniRef50_A0Z6D1 Cluster: Malate/L-lactate dehydrogenase family p... 90 4e-17
UniRef50_A3HWQ6 Cluster: Putative dehydrogenase; n=1; Algoriphag... 90 6e-17
UniRef50_A2SP37 Cluster: L-sulfolactate dehydrogenase; n=1; Meth... 89 8e-17
UniRef50_Q8UIX7 Cluster: Malate dehydrogenase; n=2; Rhizobiales|... 87 3e-16
UniRef50_Q5PLN6 Cluster: 2,3-diketo-L-gulonate reductase; n=35; ... 87 3e-16
UniRef50_A3SYU7 Cluster: Malate/L-lactate dehydrogenase; n=2; Su... 87 4e-16
UniRef50_Q0ART3 Cluster: Malate/L-lactate dehydrogenase; n=1; Ma... 87 6e-16
UniRef50_Q982E2 Cluster: Malate dehydrogenase-like protein; n=8;... 86 7e-16
UniRef50_A1SWJ6 Cluster: Malate/L-lactate dehydrogenase; n=4; Ba... 86 1e-15
UniRef50_Q1YYK8 Cluster: L-sulfolactate dehydrogenase; n=2; Vibr... 85 1e-15
UniRef50_Q28QF4 Cluster: Malate/L-lactate dehydrogenase; n=5; Ba... 85 2e-15
UniRef50_Q0RXU9 Cluster: Probable malate/L-lactate dehydrogenase... 85 2e-15
UniRef50_Q1FH40 Cluster: Malate/L-lactate dehydrogenase; n=2; Cl... 84 4e-15
UniRef50_A1BBM1 Cluster: Malate/L-lactate dehydrogenase; n=1; Pa... 83 7e-15
UniRef50_UPI0000E470A0 Cluster: PREDICTED: hypothetical protein,... 82 1e-14
UniRef50_A1WAI4 Cluster: Malate/L-lactate dehydrogenase; n=18; P... 82 1e-14
UniRef50_Q1YQC0 Cluster: Hypothetical oxidoreductase yiaK; n=1; ... 80 6e-14
UniRef50_Q11D61 Cluster: Malate/L-lactate dehydrogenase; n=1; Me... 79 1e-13
UniRef50_A3K6M0 Cluster: Malate/L-lactate dehydrogenase family p... 79 1e-13
UniRef50_Q5DB34 Cluster: SJCHGC06758 protein; n=1; Schistosoma j... 78 2e-13
UniRef50_A3YAI3 Cluster: Malate/L-lactate dehydrogenase family p... 77 4e-13
UniRef50_A3XSZ7 Cluster: Hypothetical oxidoreductase yiaK; n=1; ... 75 1e-12
UniRef50_Q1GLV8 Cluster: Malate/L-lactate dehydrogenase; n=5; Rh... 75 2e-12
UniRef50_Q3S8E9 Cluster: Putative malate/L-lactate dehydrogenase... 75 2e-12
UniRef50_A1WRH9 Cluster: Malate/L-lactate dehydrogenase; n=2; Bu... 73 7e-12
UniRef50_A4SB62 Cluster: Predicted protein; n=2; Ostreococcus|Re... 72 1e-11
UniRef50_Q5QTW6 Cluster: Malate/L-lactate dehydrogenase family e... 71 3e-11
UniRef50_Q125C6 Cluster: Malate/L-lactate dehydrogenase; n=1; Po... 70 5e-11
UniRef50_Q98CD3 Cluster: Mll5197 protein; n=1; Mesorhizobium lot... 70 7e-11
UniRef50_A6VRA6 Cluster: Malate/L-lactate dehydrogenase; n=1; Ma... 70 7e-11
UniRef50_Q1QWQ4 Cluster: Malate/L-lactate dehydrogenase; n=4; Ga... 69 9e-11
UniRef50_Q1R3L9 Cluster: Putative lactate dehydrogenase; n=6; En... 68 2e-10
UniRef50_Q4KAT3 Cluster: Malate/L-lactate dehydrogenase family p... 68 3e-10
UniRef50_Q1YHD0 Cluster: Putative malate/L-lactate dehydrogenase... 68 3e-10
UniRef50_A4YFT2 Cluster: Malate/L-lactate dehydrogenase; n=1; Me... 67 5e-10
UniRef50_A3JKA4 Cluster: Probable L-malate dehydrogenase; n=1; M... 66 6e-10
UniRef50_Q9I492 Cluster: Uncharacterized oxidoreductase PA1252; ... 66 1e-09
UniRef50_Q8YB95 Cluster: MALATE DEHYDROGENASE; n=11; Alphaproteo... 64 3e-09
UniRef50_Q11CF6 Cluster: Malate/L-lactate dehydrogenase; n=1; Me... 63 6e-09
UniRef50_Q11B93 Cluster: Malate/L-lactate dehydrogenase; n=1; Me... 62 1e-08
UniRef50_Q92YR7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 61 3e-08
UniRef50_Q5ARM7 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q96YT3 Cluster: 318aa long hypothetical malate dehydrog... 58 2e-07
UniRef50_Q46QD8 Cluster: Malate/L-lactate dehydrogenase; n=4; Bu... 58 3e-07
UniRef50_A7CY20 Cluster: Malate/L-lactate dehydrogenase; n=1; Op... 57 4e-07
UniRef50_Q1M4M8 Cluster: Putative L-lactate dehydrogenase; n=1; ... 57 5e-07
UniRef50_UPI000050FF64 Cluster: COG2055: Malate/L-lactate dehydr... 50 6e-05
UniRef50_Q7WEF1 Cluster: Putative malate/L-lactate dehydrogenase... 49 1e-04
UniRef50_Q1M3V2 Cluster: Putative malate/lactate dehydrogenase f... 48 2e-04
UniRef50_Q8GKS5 Cluster: NalP; n=5; Neisseria meningitidis|Rep: ... 38 0.33
UniRef50_Q9A3U5 Cluster: Peptidase, M20/M25/M40 family; n=27; Pr... 37 0.44
UniRef50_Q9XBE9 Cluster: Putative phosphonopyruvate decarboxylas... 37 0.44
UniRef50_UPI0000673706 Cluster: COG2055: Malate/L-lactate dehydr... 37 0.59
UniRef50_Q1NGL2 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_Q019K7 Cluster: Putative phosphate/phosphoenolpyruvate ... 36 1.0
UniRef50_A4RXB0 Cluster: DMT family transporter: glucose-6-phosp... 35 1.8
UniRef50_Q92S49 Cluster: Nicotinate phosphoribosyltransferase; n... 35 2.4
UniRef50_Q3A839 Cluster: Molybdopterin oxidoreductase/precorrin-... 34 4.1
UniRef50_Q5ADQ7 Cluster: Possible secreted protein; n=1; Candida... 34 4.1
UniRef50_A0T6Y3 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q2HG74 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_A7EDA2 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q7NUQ9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_Q9LX31 Cluster: Tetrapyrrole-binding protein, chloropla... 33 7.2
UniRef50_UPI00006DB94B Cluster: hypothetical protein BdolA_01003... 33 9.5
UniRef50_Q9K8R2 Cluster: Glutamate-1-semialdehyde 2,1-aminomutas... 33 9.5
UniRef50_Q02BJ5 Cluster: Putative uncharacterized protein precur... 33 9.5
UniRef50_A5P3G4 Cluster: Putative uncharacterized protein precur... 33 9.5
UniRef50_Q67W22 Cluster: Putative uncharacterized protein OSJNBa... 33 9.5
>UniRef50_Q9VP68 Cluster: CG10512-PA, isoform A; n=5;
Sophophora|Rep: CG10512-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 446
Score = 255 bits (625), Expect = 7e-67
Identities = 124/230 (53%), Positives = 164/230 (71%), Gaps = 1/230 (0%)
Frame = +2
Query: 47 LSTVMPE-VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYIN 223
+S P+ V V E+RRFM D AV P + A+AQADLL+ AD GH+SHG+NRLE YIN
Sbjct: 86 MSAAAPKLVAVAESRRFMIDCFKAVKVPQAHAEAQADLLVAADHRGHFSHGMNRLEMYIN 145
Query: 224 DILSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRS 403
D+ +TD A P ILKE+ ATA VDG + LGA VGN+CMD+AI+KA+ GVGWV A+ S
Sbjct: 146 DLAINSTDGAAVPKILKETPATAWVDGLNGLGAVVGNYCMDLAIKKAKTVGVGWVCAKGS 205
Query: 404 NHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVD 583
NHYGMAG++A++A QGL+G+S TN+SP++ PTR+K +ALGTNP++L A A NGD ++D
Sbjct: 206 NHYGMAGWYAIRAMDQGLVGMSMTNTSPLMAPTRAKEAALGTNPLSLGANATNGDKFLLD 265
Query: 584 LATTAVAMGKVEIQVHKRGAVASWLGSRPRRKNYH*C*IGFRTAKLLPLG 733
+ATTAVA+GK+EIQ K + P + + +GF T L+PLG
Sbjct: 266 MATTAVAVGKIEIQRRKGAPLPDGWAQDPSGEVTNDAELGFSTGCLMPLG 315
>UniRef50_Q7PI68 Cluster: ENSANGP00000025275; n=5; Bilateria|Rep:
ENSANGP00000025275 - Anopheles gambiae str. PEST
Length = 363
Score = 251 bits (615), Expect = 1e-65
Identities = 123/222 (55%), Positives = 154/222 (69%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
V VEEARRFM D L P + AK QADLL+ AD GH+SHG+NRLE YIND+ A +
Sbjct: 12 VAVEEARRFMVDCLVKSNTPPAHAKQQADLLVEADYRGHFSHGMNRLEMYINDLHKNACN 71
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
A P +L E+ ATA VDG + LGA VGNFCMD+AIRKA+E GVGWV A+RSNHYG+AG+
Sbjct: 72 GSAVPAVLNETPATAWVDGNNGLGAVVGNFCMDLAIRKAKEVGVGWVCAKRSNHYGIAGW 131
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+ L+A G IG+S TN+SP+ PTRSK +ALGTNPI++ AP K+GD V+D+ATTAVA+
Sbjct: 132 YTLRAMNAGCIGMSMTNTSPLASPTRSKEAALGTNPISVGAPGKDGDGFVLDMATTAVAV 191
Query: 608 GKVEIQVHKRGAVASWLGSRPRRKNYH*C*IGFRTAKLLPLG 733
GK+E+Q K + P + F TA L+PLG
Sbjct: 192 GKIEMQRRKNEPIPVGWAQGPDGHPTTDASVAFDTACLMPLG 233
>UniRef50_A7RTU3 Cluster: Predicted protein; n=5; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 385
Score = 213 bits (520), Expect = 4e-54
Identities = 97/189 (51%), Positives = 136/189 (71%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
V V + F+E +T VG + A+ +L D GH+SHGLNRLE Y++DI T
Sbjct: 34 VKVADVESFIERCMTKVGTTEAHARQLGQVLTAGDVRGHFSHGLNRLEMYVHDIQEGTTV 93
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
KP ++K++AATA VDG + LG VGNFCMD+AI KA++ GV WV + SNHYG+AG+
Sbjct: 94 YTGKPTVVKQTAATAFVDGNNLLGPVVGNFCMDLAINKAKDVGVSWVVCKGSNHYGIAGW 153
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+ L+A ++GLIG+S TN+SP++VPTR + LGTNPI++AAPA+NGD+ V+D+AT+AVA+
Sbjct: 154 YTLRALEEGLIGISVTNTSPLVVPTRGRGVTLGTNPISVAAPAQNGDSFVLDMATSAVAL 213
Query: 608 GKVEIQVHK 634
GK+E+ K
Sbjct: 214 GKIEMNRRK 222
>UniRef50_UPI0000D568D3 Cluster: PREDICTED: similar to CG10512-PA,
isoform A; n=2; Tribolium castaneum|Rep: PREDICTED:
similar to CG10512-PA, isoform A - Tribolium castaneum
Length = 358
Score = 206 bits (502), Expect = 6e-52
Identities = 97/187 (51%), Positives = 135/187 (72%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
+EE RF++D + AV + AK A L AD GHY GLN+LE YIN+I +P
Sbjct: 22 LEEIHRFIKDCMMAVNTSENHAKVFAACLTEADYKGHYCEGLNKLETYINEIQQGGCNPN 81
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
A P ILKES TA V+G + LG V +FCMD+AI+KA+++G+GWV A+ SN +G+AG ++
Sbjct: 82 ADPEILKESPVTAWVNGQNGLGVVVSHFCMDLAIKKAKDSGIGWVVAKGSNSFGIAGIYS 141
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGK 613
+KA ++GL+G+SFTN SP++ PTR+ ALGTNPI++AAPA +GD+ V+D+AT AVA+GK
Sbjct: 142 VKALEEGLLGMSFTNGSPMVAPTRAMEGALGTNPISVAAPALDGDSFVLDMATAAVAVGK 201
Query: 614 VEIQVHK 634
+EI K
Sbjct: 202 IEILSRK 208
>UniRef50_UPI00015B642F Cluster: PREDICTED: similar to
ENSANGP00000025275; n=2; Endopterygota|Rep: PREDICTED:
similar to ENSANGP00000025275 - Nasonia vitripennis
Length = 412
Score = 204 bits (497), Expect = 2e-51
Identities = 96/192 (50%), Positives = 133/192 (69%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
EE RF+ D +T G+ +A A L+ AD GH+SHG+NR++ Y++DI K TD A
Sbjct: 62 EEVIRFIADCMTKAGSSREDAVTVAHHLMTADYRGHFSHGMNRMQMYVDDIRHKLTDATA 121
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
KP I+ A ALVDGC+ LG VG +CM++AI KA++ G+G V AR SNHYG++GY++L
Sbjct: 122 KPQIVNNFQAIALVDGCNGLGQIVGKYCMELAIDKARKFGIGLVTARGSNHYGISGYYSL 181
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A +Q +IG S TN+SP++ PTRS SALGTNP++L A +GD V+D+ATTAVA+GK+
Sbjct: 182 MAIEQDMIGFSCTNTSPLMAPTRSSQSALGTNPLSLGMGASDGDQFVLDMATTAVALGKI 241
Query: 617 EIQVHKRGAVAS 652
E+ K + S
Sbjct: 242 ELAHRKEQPIPS 253
Score = 42.3 bits (95), Expect = 0.012
Identities = 15/33 (45%), Positives = 25/33 (75%)
Frame = +3
Query: 612 KLKYKYTKEEPLPAGWALGPDGKTTTDAKLAFE 710
K++ + KE+P+P+GWA+ DGK TTD++ A +
Sbjct: 240 KIELAHRKEQPIPSGWAMDTDGKVTTDSEKALK 272
>UniRef50_UPI000051A408 Cluster: PREDICTED: similar to VF13D12L.3;
n=1; Apis mellifera|Rep: PREDICTED: similar to
VF13D12L.3 - Apis mellifera
Length = 406
Score = 183 bits (446), Expect = 3e-45
Identities = 89/218 (40%), Positives = 134/218 (61%)
Frame = +2
Query: 80 EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAK 259
E RF+ D L VG +A L+ +D GH+SHG+NR++ Y+ I + T+P AK
Sbjct: 58 EVIRFISDCLCKVGTTPEDAYIVGHHLMTSDYCGHFSHGMNRMQAYVLSIKNGITNPSAK 117
Query: 260 PVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
P I+ + A AL+DG + LG T+G +CM++AI KA++ G+ + R SNHYG+ GY++
Sbjct: 118 PKIVSDFQAVALIDGNNGLGHTIGKYCMELAIDKAKKYGISMITVRGSNHYGICGYYSQM 177
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVE 619
A ++ LIG + +N+SP++ PTRSK S LGTNP++L A GD ++D+ATTAVA GK+E
Sbjct: 178 AIEKDLIGFTCSNTSPLMAPTRSKISGLGTNPLSLGMGASGGDKFLLDMATTAVAFGKIE 237
Query: 620 IQVHKRGAVASWLGSRPRRKNYH*C*IGFRTAKLLPLG 733
+ + K ++ K F A+L+PLG
Sbjct: 238 LAMRKNESILKGWALGMDGKITTDARDAFNAARLMPLG 275
>UniRef50_Q9V0D5 Cluster: Malate dehydrogenase; n=3; Archaea|Rep:
Malate dehydrogenase - Pyrococcus abyssi
Length = 362
Score = 161 bits (391), Expect = 2e-38
Identities = 85/186 (45%), Positives = 119/186 (63%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
+E F+ LT +G P +AK AD LI AD G SHG+ RL+ Y++ ILS +
Sbjct: 17 DELFSFVVRVLTKLGTPEEDAKIVADNLIMADLRGIESHGVQRLKRYVDGILSGGINLHP 76
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+ I++E + AL+DG + G VG M +AI KA++ G+G VA R SNHYG+AGY+AL
Sbjct: 77 RIKIIREGPSYALLDGDEGFGQVVGYKAMKLAIEKARKTGIGIVAVRNSNHYGIAGYYAL 136
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A ++G+IG+S TNS P++ PT LGTNPIALAAP K G ++D+AT+ V +GK+
Sbjct: 137 MAAEEGMIGISMTNSRPLVAPTGGVERILGTNPIALAAPTK-GKPFLLDMATSVVPIGKL 195
Query: 617 EIQVHK 634
E+ K
Sbjct: 196 EVYRRK 201
>UniRef50_Q9I7T1 Cluster: CG18808-PA; n=3; Sophophora|Rep:
CG18808-PA - Drosophila melanogaster (Fruit fly)
Length = 385
Score = 154 bits (373), Expect = 2e-36
Identities = 74/184 (40%), Positives = 124/184 (67%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
VLV+EARRF++D L VG S+ + ++ L+ AD G+Y GLNRL++Y++D+ S
Sbjct: 34 VLVDEARRFIQDCLLRVGVSPSKVRCISEFLVVADYRGNYGSGLNRLDYYLSDLQSGHAK 93
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
A+P I+ E+ +TA V+G ALG VGNFCMD+A++KA+++G+G+V A++S+ GMA +
Sbjct: 94 VGAEPSIISETVSTAHVNGNSALGVFVGNFCMDLAVKKAEDSGIGFVVAQQSHDIGMASW 153
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+ +A +GL G+ +NS+P ++ SK++++G+N A + + V+D+AT+ +
Sbjct: 154 FTFRAAGKGLAGIVMSNSAPTMMGPNSKSASIGSNCFAFCVKGEE-YHFVLDMATSVKDI 212
Query: 608 GKVE 619
G VE
Sbjct: 213 GAVE 216
>UniRef50_Q2LTF1 Cluster: Malate/L-lactate dehydrogenase; n=1;
Syntrophus aciditrophicus SB|Rep: Malate/L-lactate
dehydrogenase - Syntrophus aciditrophicus (strain SB)
Length = 373
Score = 148 bits (358), Expect = 2e-34
Identities = 71/182 (39%), Positives = 114/182 (62%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
++ +F++ ++ G +A AD L+ AD G SHG+ RL Y++ + + P +
Sbjct: 18 QKLTQFVQKIFSSFGVTREDAVICADNLVLADLRGIPSHGVARLRRYVDGMSNGTILPHS 77
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
KP+I++E+ +TA VDG LG VG+F +AI KA++ GVG VA R SNHYG+AGY+
Sbjct: 78 KPIIVREAPSTATVDGQAGLGQIVGHFSTQLAIEKARKTGVGIVAVRNSNHYGIAGYYTQ 137
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
GL+G+S TN++P++VPT + +GTNPI++ AP + +D+AT+ + GK+
Sbjct: 138 MMLDAGLLGISMTNTAPLVVPTFGRKMIIGTNPISMTAPTRRNKPFFLDMATSVIPRGKL 197
Query: 617 EI 622
E+
Sbjct: 198 EV 199
>UniRef50_Q4J502 Cluster: Malate/L-lactate dehydrogenase; n=5;
Proteobacteria|Rep: Malate/L-lactate dehydrogenase -
Azotobacter vinelandii AvOP
Length = 450
Score = 141 bits (342), Expect = 1e-32
Identities = 81/189 (42%), Positives = 109/189 (57%), Gaps = 1/189 (0%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
M +V + R L A G P A+ A L++ D G SHG++ L FY +
Sbjct: 84 MAKVGADALRELTAAVLAAWGMPAVAAEETAALIVETDLAGIDSHGVSMLPFYETLREAG 143
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
P A+P +++ES TAL+DG LG M +A KAQ G+G VA R SNH+G
Sbjct: 144 GWVPDAEPRVVRESPCTALLDGGHGLGHRTAMQAMRLAADKAQGVGLGAVAVRNSNHFGA 203
Query: 419 AGYWALKAEKQGLIGL-SFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATT 595
AG +A A ++GLIGL + T SP+LVPTR++ LGTNPIA AAPA+ V+D+ATT
Sbjct: 204 AGLYARAAAERGLIGLVASTTRSPMLVPTRARVPVLGTNPIAFAAPARRNRPFVLDMATT 263
Query: 596 AVAMGKVEI 622
VA KV++
Sbjct: 264 TVAANKVKV 272
>UniRef50_Q8T901 Cluster: AT13460p; n=3; Sophophora|Rep: AT13460p -
Drosophila melanogaster (Fruit fly)
Length = 461
Score = 140 bits (340), Expect = 2e-32
Identities = 77/183 (42%), Positives = 108/183 (59%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
V EA+RF+ +A+ P A AD LI AD +G S G++RL D+L+
Sbjct: 98 VLEAQRFVSQVFSAMQVPKQAASEMADALIAADYMGQRSMGIHRLPSIAADLLNCTVAGD 157
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
A P I+ E A ALVDG +A G V NFCMD+A++KA+E G+GWV+AR SN G A ++A
Sbjct: 158 ATPGIVSEKKAIALVDGHNAPGPVVANFCMDLALQKAREVGIGWVSARSSNCIGFASWYA 217
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGK 613
+A +Q +IGL TN++P LVP LG NPIA AA + + V D A ++ +
Sbjct: 218 CQALEQRMIGLCMTNAAPTLVPAGGIEPVLGENPIACAASGVH-EQFVADFGMAACSVDE 276
Query: 614 VEI 622
+E+
Sbjct: 277 LEL 279
>UniRef50_Q58820 Cluster: L-sulfolactate dehydrogenase (EC
1.1.1.272) ((R)-sulfolactate dehydrogenase)
((R)-2-hydroxyacid dehydrogenase); n=6;
Methanococcales|Rep: L-sulfolactate dehydrogenase (EC
1.1.1.272) ((R)-sulfolactate dehydrogenase)
((R)-2-hydroxyacid dehydrogenase) - Methanococcus
jannaschii
Length = 344
Score = 140 bits (339), Expect = 3e-32
Identities = 74/187 (39%), Positives = 108/187 (57%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E ++ + D L G P +AK AD+ + AD G SHG+ R YI + +P
Sbjct: 6 ENEKKLIIDVLKKFGVPEEDAKITADVFVDADLKGFTSHGIGRFPQYITALKLGNINPKP 65
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
I+KES ATA++DG LG VG M++AI+KA+ GVG VA R +NH+G+AGY++
Sbjct: 66 DIKIVKESPATAVIDGDLGLGQVVGKKAMELAIKKAKNVGVGVVATRNANHFGIAGYYSE 125
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A Q +IG++ TN+ P + P K LGTNPIA+A N +D+AT ++A GK+
Sbjct: 126 LAMNQDMIGITITNTEPAMAPFGGKEKILGTNPIAIAFKG-NKYKFSLDMATASIARGKI 184
Query: 617 EIQVHKR 637
+ K+
Sbjct: 185 LEALRKK 191
>UniRef50_A1ZPB3 Cluster: Malate dehydrogenase; n=4;
Sphingobacteriales|Rep: Malate dehydrogenase -
Microscilla marina ATCC 23134
Length = 371
Score = 140 bits (338), Expect = 4e-32
Identities = 71/177 (40%), Positives = 102/177 (57%)
Frame = +2
Query: 92 FMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVIL 271
F +G A+ AD+LI AD G SHG+ RL Y+ K +P ++
Sbjct: 13 FARQVFKKIGCSDEHAEQAADVLISADLRGIDSHGMARLAGYVKQWEIKRLNPTPNIKVV 72
Query: 272 KESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQ 451
E+ +TA++DG LG V M +AI KAQ+ G GWVA + S H+G+AGY A+ +
Sbjct: 73 HETPSTAVIDGDAGLGLVVAPTAMQIAIEKAQKVGTGWVAIKNSGHFGIAGYHAMMPLRY 132
Query: 452 GLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
++G++ TN+S ++ PT S LGTNPIA+A P + V DLAT+AVA GK++I
Sbjct: 133 DMVGMTMTNASSLVTPTFSLDKLLGTNPIAVAVPTEKYPPFVADLATSAVAYGKMQI 189
>UniRef50_O34736 Cluster: Uncharacterized oxidoreductase yjmC; n=3;
Bacillus|Rep: Uncharacterized oxidoreductase yjmC -
Bacillus subtilis
Length = 337
Score = 136 bits (329), Expect = 5e-31
Identities = 71/191 (37%), Positives = 108/191 (56%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
+ EEA+ + L G +A+ AD+L+HAD +SHG+ E Y+N +L+ +
Sbjct: 6 IAAEEAKELVWQKLDGAGLNERDAEKVADVLVHADLRNVHSHGVLHTEHYVNRLLAGGIN 65
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
P A+PV + T ++DG D G + MD AI A++ GVG V A S+H G Y
Sbjct: 66 PGAQPVFKETGPVTGVLDGDDGFGHVNCDMAMDHAIDMAKKKGVGMVTAVNSSHCGALSY 125
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+ KA + LIG++ T++ I+VP +T LGTNPIA PAK+ ++D+AT+ VA
Sbjct: 126 FVQKAADEKLIGMAMTHTDSIVVPFGGRTPILGTNPIAYGVPAKHKKPFILDMATSKVAF 185
Query: 608 GKVEIQVHKRG 640
GK+ +Q + G
Sbjct: 186 GKI-LQAREEG 195
>UniRef50_A1HMI4 Cluster: Malate dehydrogenase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Malate dehydrogenase -
Thermosinus carboxydivorans Nor1
Length = 355
Score = 132 bits (320), Expect = 6e-30
Identities = 65/173 (37%), Positives = 100/173 (57%)
Frame = +2
Query: 116 VGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATAL 295
VG P E+ A+ L+ AD G SHG++R+ Y+ I A +P + ES +TA+
Sbjct: 24 VGVPRDESYINAENLVDADLTGVESHGVSRMPIYLKRIRMNAVNPRCTLRTVSESPSTAV 83
Query: 296 VDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFT 475
+D C+++GA VG M++AI KA++ G+ ++ + SNHYG A Y A A K +IG + T
Sbjct: 84 IDACNSMGAVVGVKTMELAIEKAKKTGISFIVVKNSNHYGTAAYHAKIALKHNMIGFTAT 143
Query: 476 NSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQVHK 634
N + + P K GTNP A+A PA ++ D+AT+ VA+GK+ + K
Sbjct: 144 NGAARMAPWGGKDPFFGTNPFAVAVPAGKHLPIIADMATSVVALGKIILAAKK 196
>UniRef50_Q88T45 Cluster: Malate dehydrogenase; n=1; Lactobacillus
plantarum|Rep: Malate dehydrogenase - Lactobacillus
plantarum
Length = 362
Score = 129 bits (311), Expect = 8e-29
Identities = 68/168 (40%), Positives = 101/168 (60%)
Frame = +2
Query: 119 GAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALV 298
G E++ A +LI+ D +G SHG+ R+ Y + I + +P ++KE+ +A+V
Sbjct: 22 GFTEEESQEVAHMLIYTDLIGIESHGVQRMIMYDDFIRNGKIRVHNRPEVVKETDVSAVV 81
Query: 299 DGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTN 478
D LG G + M +AI KA++ G+G V R S HYG+AGY+A A ++GLIGLS N
Sbjct: 82 DAHFGLGQLNGIYSMRLAIEKAKQHGIGIVTTRNSGHYGIAGYYANMAAEEGLIGLSSCN 141
Query: 479 SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
S ++PT + + +GTNPIA A PA N + + D ATT V GK+E+
Sbjct: 142 SRSAMLPTHATKALVGTNPIAFAMPA-NPNTFIFDAATTTVPQGKIEV 188
>UniRef50_A0VVP8 Cluster: Malate dehydrogenase; n=3; Bacteria|Rep:
Malate dehydrogenase - Dinoroseobacter shibae DFL 12
Length = 351
Score = 128 bits (309), Expect = 1e-28
Identities = 69/190 (36%), Positives = 105/190 (55%), Gaps = 3/190 (1%)
Frame = +2
Query: 59 MPE--VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDIL 232
MP+ + E + F+ +L+A G P +A A L++ AD G+ +HG+ RL Y+ +
Sbjct: 1 MPDDTISAEALQDFVARALSARGVPTQDANKVAGLMVEADIYGYGTHGVFRLRQYLARLE 60
Query: 233 SKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHY 412
+P +L+++ ATAL+DG + G D+A+ KA++AG+GWV RR NH
Sbjct: 61 GGGCNPAPNISVLQQTVATALIDGDNGFGHLAMAAARDLAMEKARQAGIGWVGVRRGNHA 120
Query: 413 GMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTS-ALGTNPIALAAPAKNGDNLVVDLA 589
G + + GL+G++ S VP T LGTNPIA +APA+ D V D+A
Sbjct: 121 GPLALYVRPQAEAGLLGMAAAVGSANHVPPYGGTDLLLGTNPIAFSAPAEGPDPFVFDMA 180
Query: 590 TTAVAMGKVE 619
TT AMGK++
Sbjct: 181 TTVAAMGKIK 190
>UniRef50_Q01XF2 Cluster: Malate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Malate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 344
Score = 127 bits (307), Expect = 2e-28
Identities = 68/186 (36%), Positives = 102/186 (54%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
MP + V+ +F E L G P +A+ L+ ++ G SHG+ L FYI+ +L+
Sbjct: 1 MPTISVQHLTQFCEAILEGAGVPRHKAEVTTGCLVASNLRGVDSHGIQLLPFYIDQLLAG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
D A+ ++ ES + DG +ALG V C A+R A+E G+ V AR SNH+G
Sbjct: 61 EMDAQAEGRVISESGSCLHFDGQNALGQWVAENCCKHAVRIARENGMALVVARESNHFGA 120
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
A +WA K G IG+ N+SPI+ P + + +GTNPI ++ P ++D+ATT
Sbjct: 121 AAWWAQKMRAAGQIGIVMCNASPIVPPWQGREGRMGTNPICMSVPGP----WLLDMATTT 176
Query: 599 VAMGKV 616
VA GK+
Sbjct: 177 VAAGKI 182
>UniRef50_Q2BFJ4 Cluster: Malate dehydrogenase; n=1; Bacillus sp.
NRRL B-14911|Rep: Malate dehydrogenase - Bacillus sp.
NRRL B-14911
Length = 364
Score = 127 bits (306), Expect = 3e-28
Identities = 67/186 (36%), Positives = 106/186 (56%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E+ ++F D G +A+ A+ LI AD G SHG+ R + YI I +P A
Sbjct: 10 EKLQKFCSDVFIKAGVKREDAETVAESLIQADLRGIDSHGVVRTDIYIKRIEKNMMNPFA 69
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+ I +E+ ATALV+G + LGA VG+ +D+A+ KA+E G V + SNH+G ++
Sbjct: 70 EISIEEETDATALVNGHNQLGAIVGSKALDLALHKAKEKGAAIVGVKGSNHFGTGAFYVS 129
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
KA ++ +I L +N+S + PT +GTNP+A+ PA + ++D+AT+ VA GK+
Sbjct: 130 KAIEKDMILLVLSNASQTMPPTGGVRPFIGTNPLAIGVPAGEEEAFILDMATSVVARGKI 189
Query: 617 EIQVHK 634
+ K
Sbjct: 190 IVAAQK 195
>UniRef50_A6ULS2 Cluster: Malate/L-lactate dehydrogenase; n=1;
Sinorhizobium medicae WSM419|Rep: Malate/L-lactate
dehydrogenase - Sinorhizobium medicae WSM419
Length = 348
Score = 126 bits (304), Expect = 6e-28
Identities = 64/182 (35%), Positives = 103/182 (56%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E R F ED L A G A AD L++AD G SHG+ RL Y++ I + +
Sbjct: 10 EALRGFTEDVLKAAGMRPQPAATVADTLVYADLRGVSSHGVARLGSYLDRIRAGVMEIDP 69
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+ +++E+ A+ L+D + G G M++AI KA+ AG + SNH+G+A Y+A
Sbjct: 70 QMRLIREAPASGLLDAGNGFGQIAGMTAMEIAIEKAKSAGSAVIGIANSNHFGVAAYFAE 129
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
+A + G++G+ TNSSP + ++ +GTNPIA PA +++D++T+ VA GK+
Sbjct: 130 RATRAGMVGIVLTNSSPAMTAFNTRIPLIGTNPIAFGIPAGAERPIILDMSTSLVARGKI 189
Query: 617 EI 622
+
Sbjct: 190 RL 191
>UniRef50_Q88XU4 Cluster: Malate / lactate dehydrogenase; n=4;
Lactobacillus|Rep: Malate / lactate dehydrogenase -
Lactobacillus plantarum
Length = 362
Score = 125 bits (302), Expect = 1e-27
Identities = 69/192 (35%), Positives = 104/192 (54%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
+ E R+F+E A + AD L+ AD G SHG+ RL +Y I +
Sbjct: 3 ISAETERQFLEAVFKAQRFSAKDGALLADTLVDADLRGISSHGIQRLAWYTRMIKDHTLE 62
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
P +P IL E+ + L+D ++G F M+ I K ++ GV R SNH+G AGY
Sbjct: 63 PTHQPKILNETPTSLLIDANQSMGQIASAFTMNKLIEKTKQLGVSLAVIRNSNHFGTAGY 122
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
++ A K GLIG+S TN+ P++VPT + + LG+N +A PA + V D AT V+
Sbjct: 123 YSRMACKAGLIGISTTNTRPLVVPTNATEAFLGSNALAFTFPA-DPHPFVFDGATAVVSS 181
Query: 608 GKVEIQVHKRGA 643
GK+++ + K+GA
Sbjct: 182 GKIQV-LAKKGA 192
>UniRef50_Q8NSK9 Cluster: Malate/L-lactate dehydrogenases; n=5;
Bacteria|Rep: Malate/L-lactate dehydrogenases -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 347
Score = 124 bits (300), Expect = 2e-27
Identities = 69/188 (36%), Positives = 101/188 (53%), Gaps = 2/188 (1%)
Frame = +2
Query: 59 MPEVLV--EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDIL 232
MPEV V ++ D LT G P ++A D L+ AD GH SHG+ RL +Y+ +
Sbjct: 1 MPEVTVNAQQLTVLCTDILTKTGVPAADAHLVGDSLVQADLWGHPSHGVLRLPWYVRRLH 60
Query: 233 SKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHY 412
S A A +L + A +DG + +G + + A+ +A G+G V+ R SNH+
Sbjct: 61 SGAMTTHAHVEVLNDLGAVLALDGHNGIGQVLADHARKEAVTRAMMFGIGAVSVRNSNHF 120
Query: 413 GMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLAT 592
G A Y+ KA QG + + TN+SP + P + +GTNP ++AAP VVD+A
Sbjct: 121 GTAMYYTRKAAAQGCVSILTTNASPAMAPWGGREKRIGTNPWSIAAPF-GETATVVDIAN 179
Query: 593 TAVAMGKV 616
TAVA GK+
Sbjct: 180 TAVARGKI 187
>UniRef50_Q8TYB0 Cluster: L-sulfolactate dehydrogenase; n=1;
Methanopyrus kandleri|Rep: L-sulfolactate dehydrogenase
- Methanopyrus kandleri
Length = 341
Score = 124 bits (299), Expect = 2e-27
Identities = 62/180 (34%), Positives = 101/180 (56%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E+ F+ ++L AVG P +A+ A++++ D G +SHG+ RL YI I A P
Sbjct: 6 EDLTDFVSEALHAVGVPRKDARTAAEVIVEGDLRGFHSHGVLRLPGYIEGIKRGAIRPEM 65
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+ + ++ L D +LG VG A+ A++ G+G VA R ++HYG+AGY+
Sbjct: 66 RIEEISRKSSVVLYDADHSLGHVVGYRATLEAVELARKHGLGMVAVRNASHYGIAGYYTT 125
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
++G IG + + P + P LGTNP+++A P ++G +VVD+AT+ VA GK+
Sbjct: 126 LVAERGFIGFTTCGTEPAVAPYGGSQPVLGTNPVSIAFPRRDGPPIVVDMATSVVARGKI 185
Score = 32.7 bits (71), Expect = 9.5
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +3
Query: 612 KLKYKYTKEEPLPAGWALGPDGKTTTDAKLAFE 710
K+ + +P WA+GPDG+ TTD + A E
Sbjct: 184 KILQALRENREIPQDWAVGPDGEPTTDPEEALE 216
>UniRef50_UPI0000498ABD Cluster: malate dehydrogenase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: malate
dehydrogenase - Entamoeba histolytica HM-1:IMSS
Length = 370
Score = 122 bits (293), Expect = 1e-26
Identities = 68/183 (37%), Positives = 102/183 (55%), Gaps = 1/183 (0%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLE-FYINDILSKATDPC 253
+E +FM+D L A G ++A A +LI AD G +HG+ RL+ Y + I +
Sbjct: 12 DELEKFMKDVLMAKGVEEADAARCAKVLIQADKQGMDTHGIQRLKTIYCDRIDCGQLNTK 71
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
++KE+ TA+VDG + +G ++ M +AI KA++ G+G V R HYG+AGY+
Sbjct: 72 TVFDVVKETETTAVVDGHNGMGHSIAMQAMQLAIDKAKKHGMGMVVVRNGTHYGIAGYYP 131
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGK 613
A +QG IG S N+ P + P S LGTNP+ A P+ G +D AT+ V GK
Sbjct: 132 QMAAQQGCIGFSGCNARPSVCPCWSVEPKLGTNPLVFAFPSDEGFPFCLDCATSIVQRGK 191
Query: 614 VEI 622
+E+
Sbjct: 192 IEM 194
>UniRef50_Q8EMJ6 Cluster: Malate dehydrogenase; n=2;
Bacillaceae|Rep: Malate dehydrogenase - Oceanobacillus
iheyensis
Length = 356
Score = 121 bits (291), Expect = 2e-26
Identities = 66/195 (33%), Positives = 111/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
++ +RF D L P EA+ A+ L+ AD G SHG+ R+ Y+ + +
Sbjct: 9 KDLQRFCRDLLKQ-SLPDEEAEVIAETLVDADLRGVTSHGVQRVAGYLKRMEDGIIERKT 67
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
++++S ATAL+D + G G M++AI+KA + G +V SNH+G A ++
Sbjct: 68 DISVVQDSFATALLDANNGWGQVAGVKAMEMAIQKAGQYGTSFVGVSNSNHFGTASFYTR 127
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDN-LVVDLATTAVAMGK 613
A ++G IG+S TN+SPI+VP +K +LG NPI+++ PA G +++D++T+ VA GK
Sbjct: 128 MAAEKGFIGISMTNASPIMVPFGAKEPSLGPNPISISIPAGEGKKPIILDMSTSNVARGK 187
Query: 614 VEI-QVHKRGAVASW 655
+ + + +K W
Sbjct: 188 IMVAKKNKESIPEGW 202
Score = 34.7 bits (76), Expect = 2.4
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 612 KLKYKYTKEEPLPAGWALGPDGKTTTDAKLAFE 710
K+ +E +P GWA+ DGK TTDA A+E
Sbjct: 187 KIMVAKKNKESIPEGWAITKDGKQTTDADEAWE 219
>UniRef50_Q97LJ4 Cluster: Malate dehydrogenase; n=2;
Clostridium|Rep: Malate dehydrogenase - Clostridium
acetobutylicum
Length = 369
Score = 120 bits (288), Expect = 5e-26
Identities = 58/157 (36%), Positives = 97/157 (61%)
Frame = +2
Query: 152 DLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALVDGCDALGATVG 331
++L+ AD G SHG+ RL Y I + + I+KES + ++DG +G +
Sbjct: 41 EVLLLADLFGIESHGVQRLTLYYKGIRNGSIKVKNHMNIVKESPVSVVIDGDGGMGQIIS 100
Query: 332 NFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSK 511
M+ AI KA++ G+G + SNH+G+AGY++ AE++GL+G++ TN+ I++PT +
Sbjct: 101 KKAMERAIDKAKKTGIGMAIVKNSNHFGIAGYYSRMAERKGLMGIAMTNTRAIVLPTYGR 160
Query: 512 TSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
LGTNPI++A PA+ ++D+AT+ + GKVE+
Sbjct: 161 EQMLGTNPISIAMPAR-PIPFLLDMATSVITRGKVEV 196
>UniRef50_UPI0000499C46 Cluster: malate dehydrogenase; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: malate
dehydrogenase - Entamoeba histolytica HM-1:IMSS
Length = 351
Score = 118 bits (285), Expect = 1e-25
Identities = 69/198 (34%), Positives = 103/198 (52%), Gaps = 2/198 (1%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLE-FYINDILSKAT 244
V ++ + FM L VG+ A+ D LI AD G +HG+ R + YI+ I
Sbjct: 9 VSIDTIKEFMYQVLLKVGSDEENARMVRDTLIAADLRGMDTHGIQRFKTVYIDRIKKGMI 68
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
+P AKP I++E++ T ++DG + G G M +AI KA++ G+G V R S H+G+AG
Sbjct: 69 NPTAKPSIIRETSTTCVLDGNNGFGHVNGTIGMKMAIEKAKKYGMGMVVVRNSTHFGIAG 128
Query: 425 YWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
Y++L A ++G IG+ TN+ + T LGTNP+A+ P D AT+
Sbjct: 129 YYSLLAAQEGCIGICGTNARSSVAATFGDEPILGTNPLAIGIPLDEAFPYCFDGATSISP 188
Query: 605 MGKVEIQVHKRGAV-ASW 655
G+ E V V SW
Sbjct: 189 TGRFEKYVRMGKTVDKSW 206
>UniRef50_Q4FMG7 Cluster: Malate/L-sulfolactate dehydrogenase
multifunction enzyme; n=2; Candidatus Pelagibacter
ubique|Rep: Malate/L-sulfolactate dehydrogenase
multifunction enzyme - Pelagibacter ubique
Length = 336
Score = 118 bits (284), Expect = 1e-25
Identities = 61/179 (34%), Positives = 100/179 (55%)
Frame = +2
Query: 86 RRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPV 265
+R ++D A A+ LI+A+ VG SHGL+RL+ Y + I K +P AK
Sbjct: 7 KRIIKDIFIKYKLNKDHATICAEALINAELVGAPSHGLSRLKMYCDRISKKVINPKAKIK 66
Query: 266 ILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAE 445
+ K S + A VDG +++G + + AI A++ G+G VA + S HYG++GY+A +A
Sbjct: 67 VKKISQSIAHVDGNNSIGFVAADTAIKTAISNAKKTGIGLVAVKNSGHYGLSGYYAEQAV 126
Query: 446 KQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
K+GL+ + FTN+ P + P + S GTNPI P + ++D + + + GK+ +
Sbjct: 127 KKGLMVMVFTNAPPAVAPHGALKSLFGTNPICFGTPTGSKVPFILDTSISMINRGKIRV 185
>UniRef50_Q746L8 Cluster: Dehydrogenase; n=2; Thermus
thermophilus|Rep: Dehydrogenase - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 344
Score = 118 bits (283), Expect = 2e-25
Identities = 76/187 (40%), Positives = 100/187 (53%), Gaps = 1/187 (0%)
Frame = +2
Query: 98 EDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKE 277
E L GA AKA A L+ AD G SHGL RL Y+ + + +P + + L+E
Sbjct: 13 EALLRKAGADEPSAKAVAWALVEADLRGVGSHGLLRLPVYVRRLEAGLVNP-SPTLPLEE 71
Query: 278 SAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGL 457
AL+DG G V ++ A A+ G+G V RRS H+GMAG +A K + G
Sbjct: 72 RGPVALLDGEHGFGPRVALKAVEAAQSLARRHGLGAVGVRRSTHFGMAGLYAEKLAQAGF 131
Query: 458 IGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQVHKR 637
+ L TN+ P +VP + ALGTNP+A AAPA G LV DLAT+ AMGKV + K
Sbjct: 132 LALVTTNAEPDVVPFGGREKALGTNPLAFAAPAPQG-ILVADLATSESAMGKVFLAREKG 190
Query: 638 GAV-ASW 655
+ SW
Sbjct: 191 ERIPPSW 197
>UniRef50_A1DHT6 Cluster: Malate/L-lactate dehydrogenase, putative;
n=14; Pezizomycotina|Rep: Malate/L-lactate
dehydrogenase, putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 356
Score = 117 bits (281), Expect = 3e-25
Identities = 63/183 (34%), Positives = 96/183 (52%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
V + AR F++ LT G A AD L+ AD G +HG+NR+ Y+ I D
Sbjct: 10 VSADNARTFVQSVLTGNGVSPENATIIADCLVRADLRGVDTHGINRIPSYMERIRQGVLD 69
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
A PV+ + + A VDG + G + M AI A+E G+G+V+ + SNH+GM+ +
Sbjct: 70 AKANPVLNQITPVVAQVDGKNGFGFVAAHLGMKRAIEMAREFGIGFVSVKHSNHFGMSAW 129
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+A G++ L FTNSSP L + +G +P+A APA ++D+A + A
Sbjct: 130 VVQQALDAGMMSLVFTNSSPALPVWGGREKLMGVSPLACGAPAGKEKPFILDMAPSIAAR 189
Query: 608 GKV 616
GK+
Sbjct: 190 GKI 192
>UniRef50_O27273 Cluster: L-sulfolactate dehydrogenase (EC 1.1.1.-)
((R)-sulfolactate dehydrogenase); n=4;
Methanobacteriales|Rep: L-sulfolactate dehydrogenase (EC
1.1.1.-) ((R)-sulfolactate dehydrogenase) -
Methanobacterium thermoautotrophicum
Length = 341
Score = 116 bits (278), Expect = 8e-25
Identities = 63/188 (33%), Positives = 103/188 (54%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
EE + +++ LTA+ P + AD+ + AD G SHG+ R Y++ +
Sbjct: 6 EEEVKIIKEILTAMNVPEESSDIVADVTLDADLKGFSSHGIGRFPQYVDGLRHGTIRADG 65
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
I +E+ +TAL++G G V M++AI KA+ GVG V SNH+G+AGY++
Sbjct: 66 DITIERETESTALINGNHIFGHVVAYRAMELAIEKARNTGVGLVGVHDSNHFGVAGYYSD 125
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A +IG+ N+ P + P + LGTNP+A+ P+ N + VD+AT+A A GK+
Sbjct: 126 MAVMNDMIGVVIANTEPAVAPIGGRKPILGTNPVAIGIPS-NRYYVSVDMATSASARGKL 184
Query: 617 EIQVHKRG 640
++ ++G
Sbjct: 185 -LEAARKG 191
>UniRef50_Q1YDL3 Cluster: Putative malate/L-lactate dehydrogenase;
n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
malate/L-lactate dehydrogenase - Aurantimonas sp.
SI85-9A1
Length = 352
Score = 114 bits (274), Expect = 2e-24
Identities = 69/187 (36%), Positives = 95/187 (50%), Gaps = 2/187 (1%)
Frame = +2
Query: 86 RRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPV 265
R F A G A D+LIHAD GH SHGL R+ Y I + A + A+P
Sbjct: 10 RPFANALFEASGLSQDHAALVTDVLIHADLRGHGSHGLTRIPIYAERIAAGAVN--ARPD 67
Query: 266 ILKESAATAL--VDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
I E A A VDG + G V + ++ AI A+E GV A RSNH G ++ K
Sbjct: 68 IRFERPAPAFLQVDGDNGPGPVVSDAAVEAAIATAKEQGVCVAAVARSNHNGSGSFYVEK 127
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVE 619
A G I L+ TN+ P + + + +GTNP+ P G +++D+AT+ VA GKV
Sbjct: 128 AVAAGCIALAMTNAPPSMAVFGGRQAVIGTNPVTFGTPVDGGTPIMMDMATSVVARGKV- 186
Query: 620 IQVHKRG 640
++ KRG
Sbjct: 187 VEAAKRG 193
>UniRef50_Q28JS2 Cluster: Malate/L-lactate dehydrogenase; n=1;
Jannaschia sp. CCS1|Rep: Malate/L-lactate dehydrogenase
- Jannaschia sp. (strain CCS1)
Length = 362
Score = 112 bits (269), Expect = 1e-23
Identities = 66/187 (35%), Positives = 98/187 (52%), Gaps = 2/187 (1%)
Frame = +2
Query: 56 VMPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGH--YSHGLNRLEFYINDI 229
VM V E+ R F+ + A+G +A A+ LI ++ H G+ RL Y I
Sbjct: 6 VMTNVDREQLRTFVAEGFRALGLTEEDAGIFANALIFSELRFHPGQGQGVARLRRYHERI 65
Query: 230 LSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNH 409
+ +P A I+KE A ALVD + +G + M +AI+KA+E G+G V R S H
Sbjct: 66 GNGEVNPRAGWSIVKEGPALALVDAHNGIGTVAASKAMALAIKKAKEGGIGTVVVRNSTH 125
Query: 410 YGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLA 589
YG + A +A + G IG++FTN+ P + P + GTNP ++AAP+ G V+D+A
Sbjct: 126 YGSSAVHACQALEHGCIGVAFTNAGPEMAPWGGREGVTGTNPWSIAAPSDQGFPTVLDIA 185
Query: 590 TTAVAMG 610
T G
Sbjct: 186 ITTAGKG 192
>UniRef50_Q1YIU0 Cluster: Putative malate dehydrogenase; n=1;
Aurantimonas sp. SI85-9A1|Rep: Putative malate
dehydrogenase - Aurantimonas sp. SI85-9A1
Length = 381
Score = 112 bits (269), Expect = 1e-23
Identities = 60/173 (34%), Positives = 94/173 (54%), Gaps = 1/173 (0%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
L+A G + A AD+L+ AD +G SHGL L Y + + ++ + A
Sbjct: 45 LSAWGMSDAHAAVTADVLVAADLMGIDSHGLTLLPLYDQQLGNGGATATPNIEVVHDMGA 104
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
AL+DG G G +D+A +A G+ ++ R SNHYG AG + + +QGL+G+
Sbjct: 105 VALIDGDAGFGQVPGMMAVDMAAERAGRFGISAISIRNSNHYGAAGVYVRRLAEQGLVGI 164
Query: 467 SFTNS-SPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
S ++ +VPT LGTNPIA AAP+ G ++D+AT+ A+GK+++
Sbjct: 165 STSSVWRAGIVPTGGLAPKLGTNPIAFAAPSARGQPFLLDMATSTAAIGKLKL 217
>UniRef50_A6UCA9 Cluster: Malate/L-lactate dehydrogenase; n=2;
Sinorhizobium|Rep: Malate/L-lactate dehydrogenase -
Sinorhizobium medicae WSM419
Length = 356
Score = 111 bits (268), Expect = 1e-23
Identities = 64/187 (34%), Positives = 105/187 (56%)
Frame = +2
Query: 56 VMPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILS 235
V P++L EAR +E++L GA A A ++HA +G SHG+ + Y +
Sbjct: 7 VAPDLL--EAR--VENALRNAGAAQGSAAAAVRAMMHASLIGVDSHGVRLVVHYDRVLRG 62
Query: 236 KATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYG 415
+ + + +AATA+VDG +ALG MD AI A+E+G+G V RS+H+G
Sbjct: 63 GRVNGTPNLSVRRTAAATAVVDGDNALGHHAAYVAMDKAIELARESGIGAVGVIRSSHFG 122
Query: 416 MAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATT 595
AG +A A + G+IG + TNS ++ P + + GTNP+A AAP+ ++D+AT+
Sbjct: 123 AAGAYARVAAEAGMIGFATTNSDKVVAPFQGREPFHGTNPLAFAAPSGGARPWLLDMATS 182
Query: 596 AVAMGKV 616
++ + ++
Sbjct: 183 SIPLNRL 189
>UniRef50_Q2UP42 Cluster: Malate/L-lactate dehydrogenases; n=2;
Aspergillus|Rep: Malate/L-lactate dehydrogenases -
Aspergillus oryzae
Length = 369
Score = 110 bits (264), Expect = 4e-23
Identities = 59/186 (31%), Positives = 101/186 (54%)
Frame = +2
Query: 83 ARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKP 262
A +F + L G +AK+ AD L+ AD G +HGL RL Y++ + + +
Sbjct: 23 AGKFASELLVKAGLSPEDAKSMADCLVMADVRGVDTHGLARLPQYLDRVSNGRVKANPEF 82
Query: 263 VILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKA 442
+ +++ A +DG + G V M+ A+++A+ G+G V SNH+GMA + ++A
Sbjct: 83 KLTEKTPVVAQLDGDNGFGFVVATRAMEEAVKRAEIYGIGMVTVNHSNHFGMAATYVIQA 142
Query: 443 EKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
++ +I L FTNS+ + P K + LG +P A AP+ N ++D+A + VA GK+
Sbjct: 143 LEKNMISLVFTNSAKQMPPFGGKETLLGISPFAAGAPSNNEVPYILDMAPSVVAKGKIR- 201
Query: 623 QVHKRG 640
+ +RG
Sbjct: 202 RAARRG 207
Score = 34.3 bits (75), Expect = 3.1
Identities = 14/31 (45%), Positives = 19/31 (61%)
Frame = +3
Query: 612 KLKYKYTKEEPLPAGWALGPDGKTTTDAKLA 704
K++ + E +P GWAL DG TTDA +A
Sbjct: 199 KIRRAARRGESIPLGWALDADGNPTTDANIA 229
>UniRef50_Q11AU4 Cluster: Malate/L-lactate dehydrogenase; n=5;
Rhizobiales|Rep: Malate/L-lactate dehydrogenase -
Mesorhizobium sp. (strain BNC1)
Length = 337
Score = 109 bits (263), Expect = 5e-23
Identities = 69/186 (37%), Positives = 93/186 (50%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
MP V V+EAR+ + L GAP + A Q DLLI A+ G SHGL RL I I +
Sbjct: 1 MPIVSVKEARKVAGEVLRRAGAPAANADLQRDLLIEAELRGLASHGLLRLPRIIERIANG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
DP + VDG LG V ++VA R+A+E GV A SNH GM
Sbjct: 61 VADPRTSGRHEWRAPGFLQVDGQMGLGPVVAMKAIEVARRRAREHGVAVAAISNSNHIGM 120
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
++A G I ++ + S ++ P + + +GTNPIA P + G + D AT
Sbjct: 121 LAFYAEHVAADGQIMIALSTSEALVHPWGGRRAMIGTNPIAFGIPTETGP-YIADTATGH 179
Query: 599 VAMGKV 616
VAMGK+
Sbjct: 180 VAMGKI 185
Score = 33.1 bits (72), Expect = 7.2
Identities = 12/20 (60%), Positives = 15/20 (75%)
Frame = +3
Query: 633 KEEPLPAGWALGPDGKTTTD 692
++EP+P GWAL DG TTD
Sbjct: 191 RDEPIPLGWALDIDGNPTTD 210
>UniRef50_A6C467 Cluster: Malate dehydrogenase; n=1; Planctomyces
maris DSM 8797|Rep: Malate dehydrogenase - Planctomyces
maris DSM 8797
Length = 356
Score = 109 bits (262), Expect = 7e-23
Identities = 61/165 (36%), Positives = 87/165 (52%), Gaps = 1/165 (0%)
Frame = +2
Query: 134 EAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALVDGCDA 313
EA+ AD LI AD G +SHG E Y++ + DP A+ + LKE+ A A++DG +
Sbjct: 40 EAEIAADRLIEADLRGIHSHGSRTAERYLDSMDMGDIDPRAQILTLKETPAIAVLDGSKS 99
Query: 314 LGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSPIL 493
+G M++AI+KA E G G V + S+H+G A + L A K G+IG TN+
Sbjct: 100 MGHVAATRAMELAIKKAGEVGTGTVVVKNSHHFGAAAVYVLMAVKAGMIGYCTTNTGRAT 159
Query: 494 VPTRSKT-SALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQ 625
V T A N IA P + G V+D+A + GK+E Q
Sbjct: 160 VAAHGSTQGATANNAIAWGVPTREGAPFVLDMACAKTSWGKLETQ 204
>UniRef50_Q18X65 Cluster: Malate/L-lactate dehydrogenase; n=2;
Desulfitobacterium hafniense|Rep: Malate/L-lactate
dehydrogenase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 352
Score = 108 bits (260), Expect = 1e-22
Identities = 62/183 (33%), Positives = 96/183 (52%), Gaps = 2/183 (1%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
V RRFME + TA G ++ + D L++A+ G SHG++R Y+ I A +P
Sbjct: 12 VNTLRRFMEQAFTACGVSEADGQIVVDNLLYAELRGIKSHGVSRFPVYLRRIQMGAVNP- 70
Query: 254 AKPVILKESAATAL--VDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
+P I E L VDG + LG+ V ++ + A++ G+ V + SNH G +GY
Sbjct: 71 -QPQISMEQRTPVLLKVDGDNGLGSVVMVHALNRGMELAEQLGICAVGIKGSNHCGASGY 129
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+ A +QGL+ + T+ P P + + GTNP+A P +++VDLAT+ A
Sbjct: 130 YCELAAEQGLVSIVLTDGPPATPPWGGRKAYFGTNPMAFGLPRAQKPHIIVDLATSLAAR 189
Query: 608 GKV 616
GKV
Sbjct: 190 GKV 192
>UniRef50_Q89GS1 Cluster: Bll6274 protein; n=2;
Alphaproteobacteria|Rep: Bll6274 protein -
Bradyrhizobium japonicum
Length = 349
Score = 108 bits (259), Expect = 2e-22
Identities = 67/182 (36%), Positives = 99/182 (54%), Gaps = 5/182 (2%)
Frame = +2
Query: 86 RRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPV 265
R F D L A G +A A +L+ A+ G SHG+ R+ Y+ + +P A+P
Sbjct: 16 RPFAADLLRAGGFTADQADETAAMLVWANLRGADSHGVLRIPRYVEMVELGLINPAAEPR 75
Query: 266 ILKESAATALVDGCDALGATVGNFCMDVAIRKAQEA----GVGWVAARRSNHYGMAGYWA 433
+ A A++D A GA VG M +A RKA E G+GW A R +H G GY+A
Sbjct: 76 QVSGKGAVAVIDAQRAPGA-VG---MSLAARKASELADTHGIGWCAVRSISHAGAIGYYA 131
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDN-LVVDLATTAVAMG 610
+ + G IG+ T S P+++ S + TNPIA+AAP N D L++D++T +VA+G
Sbjct: 132 HQVAQAGRIGIVMTASKPLMIYHGSSAEGVSTNPIAIAAPTGNPDRPLLLDMSTASVALG 191
Query: 611 KV 616
K+
Sbjct: 192 KI 193
>UniRef50_Q11JG3 Cluster: Malate/L-lactate dehydrogenase; n=1;
Mesorhizobium sp. BNC1|Rep: Malate/L-lactate
dehydrogenase - Mesorhizobium sp. (strain BNC1)
Length = 375
Score = 107 bits (258), Expect = 2e-22
Identities = 61/188 (32%), Positives = 104/188 (55%), Gaps = 1/188 (0%)
Frame = +2
Query: 86 RRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPV 265
RR +E L A G P ++A AD+L AD G SHG++ L Y + A
Sbjct: 9 RRQIETILLAWGMPEAQAARTADILGWADLHGVESHGISMLVEYDMRFRAGRLKMNADFK 68
Query: 266 ILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAE 445
+++E+ + L+DG +G D AI KA+ +G+ + R S+H+G GY+ A
Sbjct: 69 VVRETPVSVLIDGDGGMGHIAYAMAADAAIEKAKASGIAVASVRNSSHFGAVGYFTELAA 128
Query: 446 KQGLIGLSFTNSSPILV-PTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
+ GLI + T+++ I V PT + LGT+P++ AAP+ + + ++D+ATT VA GK+
Sbjct: 129 RAGLIAMGATSAAGIRVAPTNGAEAKLGTDPLSFAAPSTDENPFLLDMATTTVAYGKIRN 188
Query: 623 QVHKRGAV 646
++++ ++
Sbjct: 189 KMNENASM 196
>UniRef50_Q0K2P1 Cluster: Malate/L-lactate dehydrogenase; n=4;
Burkholderiaceae|Rep: Malate/L-lactate dehydrogenase -
Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 367
Score = 107 bits (256), Expect = 4e-22
Identities = 60/186 (32%), Positives = 98/186 (52%), Gaps = 2/186 (1%)
Frame = +2
Query: 89 RFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVI 268
+++ D A G+ EA+ AD L+ A+ GH SHG+ + Y+ + + +
Sbjct: 13 QWVADLWLAAGSSAQEARLTADHLVGANLSGHDSHGVGMIPRYVLAWQADELQLNQQVSV 72
Query: 269 LKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEK 448
L ++ + +DG +G V M++AI +A+E GV + R+S+H G G+WA +A
Sbjct: 73 LHDAGSMLSLDGNRGMGQAVTAQAMNMAIGRAREHGVCVMGLRQSHHLGRVGHWAEQATA 132
Query: 449 QGLIGLSFTN--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
G+I + F N S PI+ P + GTNP + P LV+D AT+A+A+GKV +
Sbjct: 133 AGMISIHFVNVLSKPIVAPHGGYDARYGTNPFTIGVPVAGEPPLVLDFATSAIALGKVRV 192
Query: 623 QVHKRG 640
H +G
Sbjct: 193 -AHNKG 197
>UniRef50_P30178 Cluster: Uncharacterized oxidoreductase ybiC; n=31;
Proteobacteria|Rep: Uncharacterized oxidoreductase ybiC
- Escherichia coli (strain K12)
Length = 361
Score = 107 bits (256), Expect = 4e-22
Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Frame = +2
Query: 92 FMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVIL 271
F++ +G+ EAK AD LI A+ GH SHG+ + Y+ +
Sbjct: 15 FIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKTV 74
Query: 272 KESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQ 451
KE+ A +DG A G + M + I KA + G+ VA S+H G GYWA +
Sbjct: 75 KEAGAAVTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAA 134
Query: 452 GLIGLSFTN--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQ 625
G + + F + P++ P + S GTNP + P K+ L++D AT+A+A GK +
Sbjct: 135 GFVSIHFVSVVGIPMVAPFHGRDSRFGTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVA 194
Query: 626 VHK 634
HK
Sbjct: 195 WHK 197
>UniRef50_Q8FDK5 Cluster: Ureidoglycolate dehydrogenase; n=6;
Enterobacteriaceae|Rep: Ureidoglycolate dehydrogenase -
Escherichia coli O6
Length = 336
Score = 105 bits (251), Expect = 1e-21
Identities = 53/180 (29%), Positives = 92/180 (51%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E + + L G + D+L+HAD G +SHG+ R+E Y + + +
Sbjct: 9 ENLKSLVHHKLHTAGLDTDTTQQVTDVLVHADITGVHSHGVMRVEHYCTRLAAGGLNKAP 68
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+ I + S + A++D D +G + + AI+ AQ+ G+G+V+ + ++H G Y+A
Sbjct: 69 QFSIEQISPSVAILDSDDGMGHSALISATEHAIKLAQQEGLGFVSVKNTSHCGALSYFAE 128
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
+GL+ + T + + P LGTNPIA P +N ++VD+AT+A A GK+
Sbjct: 129 MITNKGLVAIVMTQTDTCVAPHGGAERFLGTNPIAFGFPVENSHPMIVDMATSATAFGKI 188
>UniRef50_P77555 Cluster: Ureidoglycolate dehydrogenase; n=23;
Bacteria|Rep: Ureidoglycolate dehydrogenase -
Escherichia coli (strain K12)
Length = 349
Score = 105 bits (251), Expect = 1e-21
Identities = 59/180 (32%), Positives = 90/180 (50%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E + +E+ L G A A++L++AD G +SHG R+E+Y I T+
Sbjct: 6 ETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREP 65
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+ + + +A++ +A G M+ AI+ AQ+ GV V R H G Y+
Sbjct: 66 EFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQ 125
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
+A + G IG+S S P++VP GTNP+A AAP + + L D+ATT A GKV
Sbjct: 126 QAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKV 185
>UniRef50_Q89D62 Cluster: Blr7581 protein; n=2; Rhizobiales|Rep:
Blr7581 protein - Bradyrhizobium japonicum
Length = 350
Score = 104 bits (250), Expect = 2e-21
Identities = 68/204 (33%), Positives = 104/204 (50%), Gaps = 4/204 (1%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
MP V + R L A GA EA A A ++A+ GH SHG+ + YI+ I +
Sbjct: 1 MPIVRADRLTRISAALLQAAGASQEEADAVATGCVNANLAGHDSHGVIAVPTYIDRIKAG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
P A I++ES T ++DG G V M + I KA+ A V R +H G
Sbjct: 61 HIVPGATWTIIQESPTTTVIDGHWGFGFHVNAKAMALTIEKAKTANVAACTVFRQSHVGR 120
Query: 419 AGYWALKAEKQGLIGLSFTNS--SP-ILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLA 589
+ L A ++G+IG++ +S SP + P K + LGTNPI++A P+ +D+A
Sbjct: 121 LAAYPLMAMREGMIGIATADSGRSPKHVAPFGGKEARLGTNPISIAVPSDLDAPFYLDMA 180
Query: 590 TTAVAMGKVEIQVHKRGAV-ASWL 658
T+AVA GK+++ V + + W+
Sbjct: 181 TSAVAAGKIQLAVARGDKIPTGWI 204
>UniRef50_A6C4Q2 Cluster: Putative dehydrogenase; n=1; Planctomyces
maris DSM 8797|Rep: Putative dehydrogenase -
Planctomyces maris DSM 8797
Length = 381
Score = 103 bits (248), Expect = 3e-21
Identities = 69/201 (34%), Positives = 97/201 (48%), Gaps = 6/201 (2%)
Frame = +2
Query: 41 HFLSTVMPEVLVEEAR---RFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLE 211
++ S +PEV V A+ F E L GA EA+ + L+ A+ +GH SHG+ RL
Sbjct: 20 NYFSEGLPEVPVISAQSLQNFTESLLLKGGANEEEARIVSHSLVDANLLGHDSHGVMRLP 79
Query: 212 FYINDILSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVA 391
FY+ + K IL E+ A DGC G TV + M+ I KA GV
Sbjct: 80 FYLGRVKEGILKAGEKLQILNETPAAITGDGCWGFGQTVMHDLMNRLIEKAGTLGVSCGT 139
Query: 392 ARRSNHYGMAGYWALKAEKQGLIGLSFTN---SSPILVPTRSKTSALGTNPIALAAPAKN 562
+R++H G G +A A +G+ + N S+P + P K LGTNPI + P
Sbjct: 140 LKRASHIGRLGEYAEMAAAKGMASIICANTHGSAPRVAPVGGKRPRLGTNPICIGMPGGA 199
Query: 563 GDNLVVDLATTAVAMGKVEIQ 625
V+D T+A A GKV I+
Sbjct: 200 EGPFVLDFGTSATAEGKVRIK 220
>UniRef50_A4FEK8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Malate/L-lactate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 375
Score = 103 bits (247), Expect = 5e-21
Identities = 61/169 (36%), Positives = 87/169 (51%), Gaps = 3/169 (1%)
Frame = +2
Query: 119 GAPVSEAKAQADLLIHADTVGHYSHGL-NRLEFYINDILSKATDPCAKPVILKESAATAL 295
G P A A L + D G +HGL N Y+ S DP A+P +L + A A+
Sbjct: 34 GVPADRAHTAASALCYGDLTGLEAHGLFNLTRLYLPLFDSGRVDPAAQPRVLTDLGACAV 93
Query: 296 VDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFT 475
VD ALG MD A +A + G+G V R + H+G AG+ +A ++G+IG+
Sbjct: 94 VDSRRALGLWSAAEAMDSAADRAAQHGIGLVTVRDATHFGCAGFHTARAAERGVIGVLAG 153
Query: 476 N--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
N I P + LGTNP+++AAPA G V+D++TT V G+V
Sbjct: 154 NCGGQRIARPPGGTPAMLGTNPLSVAAPALPGHPFVLDMSTTVVPTGRV 202
>UniRef50_Q07251 Cluster: L-lactate dehydrogenase; n=6;
Burkholderiales|Rep: L-lactate dehydrogenase - Ralstonia
eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 349
Score = 103 bits (246), Expect = 6e-21
Identities = 61/194 (31%), Positives = 95/194 (48%), Gaps = 4/194 (2%)
Frame = +2
Query: 65 EVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKAT 244
++ + AR+ D L A P A A+ L+ +D G+ SHGL+ L Y + +
Sbjct: 2 KISLTSARQLARDILAAQQVPADIADDVAEHLVESDRCGYISHGLSILPNYRTALDGHSV 61
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
+P + + + + DG G VG M AI + ++ G V RRS+H G G
Sbjct: 62 NPQGRAKCVLDQGTLMVFDGDGGFGQHVGKSVMQAAIERVRQHGHCIVTLRRSHHLGRMG 121
Query: 425 YWALKAEKQGLIGLSFT---NSSPILVPTRSKTSALGTNPIALAAPAKNG-DNLVVDLAT 592
++ A G + LSFT N +P++ P + + L TNP+ A P NG LVVD+AT
Sbjct: 122 HYGEMAAAAGFVLLSFTNVINRAPVVAPFGGRVARLTTNPLCFAGPMPNGRPPLVVDIAT 181
Query: 593 TAVAMGKVEIQVHK 634
+A+A+ K + K
Sbjct: 182 SAIAINKARVLAEK 195
>UniRef50_A0VU86 Cluster: Malate/L-lactate dehydrogenase; n=1;
Dinoroseobacter shibae DFL 12|Rep: Malate/L-lactate
dehydrogenase - Dinoroseobacter shibae DFL 12
Length = 339
Score = 102 bits (244), Expect = 1e-20
Identities = 60/179 (33%), Positives = 84/179 (46%)
Frame = +2
Query: 80 EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAK 259
+AR + + TA G P A++ AD L+ A+ G HG +RLE Y+ S A+
Sbjct: 13 DARDLLFRAFTANGVPEGAARSTADALVAAEAEGQVGHGFSRLEDYVAQARSGKIVAGAE 72
Query: 260 PVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
I + + T LVD +D I A+E G +A RS+H G +
Sbjct: 73 VTITRPAPTTLLVDAGHGFAYPALERAIDEGIAVARELGTAAIAVTRSHHCGALSIHVER 132
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A K GL+ + N+ + P KT GTNPIA A P LV+DL+ + VA GKV
Sbjct: 133 AAKAGLVAMMVVNAPAAIAPWGGKTPLFGTNPIAFATPRAGSAPLVIDLSLSKVARGKV 191
>UniRef50_Q0SCF8 Cluster: Possible (R)-2-hydroxyacid dehydrogenase;
n=1; Rhodococcus sp. RHA1|Rep: Possible
(R)-2-hydroxyacid dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 358
Score = 100 bits (240), Expect = 3e-20
Identities = 58/195 (29%), Positives = 96/195 (49%)
Frame = +2
Query: 35 IIHFLSTVMPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEF 214
+IH + + +EAR +L G P +A A L+ G +HGL L
Sbjct: 1 MIHEIPNTTSLIDEQEARWLASTALVEAGVPEDDADLVAAALVDTSLRGIDTHGLRLLPQ 60
Query: 215 YINDILSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAA 394
Y++++ + + A P ++++ A L+D ALG G +A +A+ GV V
Sbjct: 61 YLDELATGVANAAACPTVVRDRGAGLLLDADGALGVLAGLAATRLAADRAKAFGVAAVGV 120
Query: 395 RRSNHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNL 574
R SNH+G A + QG+IG++ T+++ + P GTNPI++AA D L
Sbjct: 121 RNSNHFGAASVYTRHLAGQGMIGIAVTSAASRVAPYGGVEPLFGTNPISVAA-GTGDDGL 179
Query: 575 VVDLATTAVAMGKVE 619
+D+AT+ V G+V+
Sbjct: 180 ALDMATSQVCFGEVK 194
>UniRef50_Q46VE5 Cluster: (R)-2-hydroxyacid dehydrogenase; n=6;
Proteobacteria|Rep: (R)-2-hydroxyacid dehydrogenase -
Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 338
Score = 98.7 bits (235), Expect = 1e-19
Identities = 55/188 (29%), Positives = 91/188 (48%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
M + +E+ +L GA ++ A A L+ AD +G SHG++R+ Y+ +
Sbjct: 1 MSRIPMEKLEVLARSALRRAGASQLQSHATAAALVRADAMGLASHGVSRVPMYVGHLRHD 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
D A P + A+ LVD + A+R+A+E GVG A S+H+G
Sbjct: 61 RVDGQAVPTVRSTRASAVLVDAACGFAFPACELAIAEAMRRARETGVGVGAVTNSHHFGA 120
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
AG + G++G++ NS + K + GTNPIA A P + +++DL+ +
Sbjct: 121 AGLPLHTVARAGMVGIAMGNSPAAMPAWGGKRALFGTNPIAAAFPRQGRLPVLIDLSLSE 180
Query: 599 VAMGKVEI 622
VA GK+ +
Sbjct: 181 VARGKIMV 188
>UniRef50_A6C5R1 Cluster: Ureidoglycolate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Ureidoglycolate
dehydrogenase - Planctomyces maris DSM 8797
Length = 371
Score = 97.1 bits (231), Expect = 4e-19
Identities = 56/175 (32%), Positives = 88/175 (50%), Gaps = 2/175 (1%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E + F L +A AD L+ ++ G SHG+ RL Y+ I ++ P
Sbjct: 14 ESLKEFCYQLLLQANLTGHDAGLVADTLVESNLRGIDSHGVARLPHYLERIRQQSIQP-- 71
Query: 257 KPVILKESAATAL--VDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYW 430
+P + E A+ VDG LG D A+ A+++G GWV+ S+H G Y+
Sbjct: 72 RPEMQWEPLGDAVGRVDGDHGLGQLAMVKAADHAVELARDSGAGWVSICNSSHCGALAYY 131
Query: 431 ALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATT 595
L+ + G+IG +FT+ P++ P + GTNPI + AP K G +L +D+AT+
Sbjct: 132 GLRIAEAGMIGFAFTHVDPMVTPHGAAEPFCGTNPICMTAPGKEGKSLCLDMATS 186
>UniRef50_Q125D0 Cluster: Malate/L-lactate dehydrogenase; n=3;
Proteobacteria|Rep: Malate/L-lactate dehydrogenase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 364
Score = 96.7 bits (230), Expect = 5e-19
Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 2/180 (1%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
L A G+ EA A L+ A+ GH SHG+ L Y++ +L P + ++ ++ +
Sbjct: 28 LKAAGSSAEEATTVAANLVLANLSGHDSHGVGMLPRYVDAVLEGGLKPNSSVRVVLDTGS 87
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
+DG G VG M + I +A+ G + ++H G G++A A QGL+ L
Sbjct: 88 LLTLDGQRGYGQIVGEQAMALGIDRAKAHGSCIMTLGNAHHLGRIGHFAEMAVDQGLVSL 147
Query: 467 SFTN--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQVHKRG 640
F N S P++ P GTNP + P K + V+D AT+ VA GK+ + H +G
Sbjct: 148 HFVNVLSRPVVAPFGGGDGRFGTNPCCIGVPLKGREPFVLDFATSRVAQGKMRV-AHNKG 206
>UniRef50_Q9XBD3 Cluster: Putative carboxylic acid dehydrogenase;
n=1; Amycolatopsis orientalis|Rep: Putative carboxylic
acid dehydrogenase - Amycolatopsis orientalis
Length = 337
Score = 95.9 bits (228), Expect = 9e-19
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 1/185 (0%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
L A G+ +A+ A L+ +D +GH SHG+ R+ Y+ I + DP A+P
Sbjct: 16 LVAAGSSTVDAETVARSLVGSDLLGHDSHGVRRVIDYVKRIHTGLIDPRAEPKAETTRPG 75
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
T +V G A G + + G G R NH G G + Q LIGL
Sbjct: 76 TVVVHGRRAFGQLAVRRAVRELLSLVPHQGSGVAVVRECNHIGRLGEYVAMLADQDLIGL 135
Query: 467 SFTNSSPILVPTRSKTSALGTNPIALAAPAKNGD-NLVVDLATTAVAMGKVEIQVHKRGA 643
+F N+ P + P + LGTNP+A A P G +V+D AT+ +A GK+ + +
Sbjct: 136 AFGNADPTVAPYGGRERRLGTNPLAWAVPRGPGQPPIVMDWATSGIAEGKLRVARDRGEQ 195
Query: 644 VASWL 658
VA L
Sbjct: 196 VAEGL 200
>UniRef50_Q6D702 Cluster: Putative malate/lactate dehydrogenase;
n=2; Enterobacteriaceae|Rep: Putative malate/lactate
dehydrogenase - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 340
Score = 95.1 bits (226), Expect = 2e-18
Identities = 57/199 (28%), Positives = 93/199 (46%), Gaps = 2/199 (1%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
MP R ++ D LT S A AD L+ + GH SHG++ L YI+ I
Sbjct: 1 MPVFTHHYLRDYLRDRLTENDVDASIAGIVADNLVESSLKGHDSHGVSMLPRYIDAIREG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
P A+ + DG G V + I +AQ G+ V+ ++H G
Sbjct: 61 GLSPHAQAEKTLDFGPLISFDGQQGFGQLVARQALAEGIARAQTHGLAVVSLANAHHLGR 120
Query: 419 AGYWALKAEKQGLIGLSFTN--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLAT 592
G WA +A + GL+ L F N + P+++P + + + GTNP P ++ + +++D AT
Sbjct: 121 IGAWAEQAAEVGLVSLHFANVYTKPVVLPWQGQQARFGTNPFCAGIPVEHDEPVILDFAT 180
Query: 593 TAVAMGKVEIQVHKRGAVA 649
+ +A K I ++ +VA
Sbjct: 181 SVIAGNKARIAWNEGKSVA 199
>UniRef50_Q7CRW4 Cluster: AGR_L_3209p; n=5; Alphaproteobacteria|Rep:
AGR_L_3209p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 358
Score = 94.3 bits (224), Expect = 3e-18
Identities = 61/183 (33%), Positives = 92/183 (50%), Gaps = 2/183 (1%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
++E RF AVG A A ++H +G SHG+ L Y+ + +
Sbjct: 14 LDELERFCRAVFLAVGTDEETADAATRAMMHGTRLGVDSHGVRLLAHYVTALEGGRLN-- 71
Query: 254 AKPVILKESA--ATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
+P I + S A +D A GA M+ A+ A++ G+G VA R S+H+G AG
Sbjct: 72 RRPQISRVSGFGAVETIDADHAHGARATYAAMENAMALAEKFGIGAVAIRNSSHFGPAGA 131
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+AL+A +QG IGL+F NS + GTNPIA+ PA + ++D+AT+AV
Sbjct: 132 YALEAARQGYIGLAFCNSDSFVRLHDGAMRFHGTNPIAVGVPAADDMPWLLDMATSAVPY 191
Query: 608 GKV 616
+V
Sbjct: 192 NRV 194
>UniRef50_Q21D51 Cluster: (R)-2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: (R)-2-hydroxyacid dehydrogenase
- Rhodopseudomonas palustris (strain BisB18)
Length = 346
Score = 93.9 bits (223), Expect = 4e-18
Identities = 61/192 (31%), Positives = 97/192 (50%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
V E R D+L A G +A Q DLL+ A+ G SHGL RL + I + D
Sbjct: 3 VEAERVRSCAVDALMAAGVLRQDADQQVDLLLEAELRGRPSHGLLRLARIVERIDNGVID 62
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
P A ++A VDG + LG V ++ +A+E GV +NH GM +
Sbjct: 63 PRASGCHHWKAAGFLEVDGQNGLGPVVALSALEAISLRARETGVAVATIVNANHLGMLAW 122
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+A ++GL ++ + S ++ P + + LGTNP+A+ PA + V+D+A++ V+M
Sbjct: 123 YAETIARRGLTIIALSISEALVHPWGGRRAMLGTNPVAIGVPA-SPRPFVLDMASSLVSM 181
Query: 608 GKVEIQVHKRGA 643
G++ + RGA
Sbjct: 182 GQIHDHAN-RGA 192
>UniRef50_Q18Q95 Cluster: Malate/L-lactate dehydrogenase; n=2;
Desulfitobacterium hafniense|Rep: Malate/L-lactate
dehydrogenase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 359
Score = 93.9 bits (223), Expect = 4e-18
Identities = 60/188 (31%), Positives = 97/188 (51%), Gaps = 2/188 (1%)
Frame = +2
Query: 59 MPEVLVEEARR-FMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILS 235
M ++ ++A F + L A G P ++A + +L+ G +HG++RL Y+ +L
Sbjct: 9 MSQMFSDQAMNDFCQRLLEASGVPATDAGIVSSILVDTSLEGIDTHGISRLPVYLKCLLK 68
Query: 236 KATDPCAKPVILKE-SAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHY 412
+P KP I + AA A VDG + LG V M+ AI A+ G+G+ + SNH+
Sbjct: 69 GRINP--KPKIQETIDAAVARVDGDNGLGQLVAYRAMNSAIDLAKIYGIGFATVKNSNHF 126
Query: 413 GMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLAT 592
G A + A Q +IG ++TNS + P + GTNPI+ P +VVD+++
Sbjct: 127 GAASTYCKLAAAQQMIGQAYTNSPSGIPPWGGRAPYFGTNPISYGFPHAEYP-VVVDMSS 185
Query: 593 TAVAMGKV 616
+ VA G +
Sbjct: 186 STVARGNI 193
Score = 35.5 bits (78), Expect = 1.4
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +3
Query: 639 EPLPAGWALGPDGKTTTDAKLAFE 710
E +P GWA+ DGK TT+AK A E
Sbjct: 201 EEIPEGWAMDKDGKATTNAKAALE 224
>UniRef50_A0TT61 Cluster: (R)-2-hydroxyacid dehydrogenase; n=5;
Burkholderiaceae|Rep: (R)-2-hydroxyacid dehydrogenase -
Burkholderia cenocepacia MC0-3
Length = 349
Score = 92.3 bits (219), Expect = 1e-17
Identities = 55/182 (30%), Positives = 93/182 (51%), Gaps = 2/182 (1%)
Frame = +2
Query: 101 DSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKES 280
++L A+G ++A A +L+ AD G +HG +R+E Y + + +P P I E
Sbjct: 22 EALCALGLTRTDATDTATILVLADLFGLRTHGTSRIESYGSRLRIGGINPA--PSITTEQ 79
Query: 281 AATAL--VDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQG 454
A AL +DG + +G VG+ +D+A+ A+E G+ V R SNH+G ++ A QG
Sbjct: 80 VAPALYRLDGDNGIGPLVGHRALDLAMTAAREQGIACVFVRGSNHFGPVSPYSYLAAMQG 139
Query: 455 LIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQVHK 634
+ +N++ + P + LG +P+ P NG ++D+A + A K+ K
Sbjct: 140 FASIIGSNATTTIAPWGGTDARLGNSPVGFGVPNPNGRPFMLDMAISVAARAKIR-NALK 198
Query: 635 RG 640
RG
Sbjct: 199 RG 200
Score = 34.3 bits (75), Expect = 3.1
Identities = 14/34 (41%), Positives = 19/34 (55%)
Frame = +3
Query: 609 AKLKYKYTKEEPLPAGWALGPDGKTTTDAKLAFE 710
AK++ + EP+P WA GK TTD K A +
Sbjct: 191 AKIRNALKRGEPIPGDWATDAQGKPTTDPKAALD 224
>UniRef50_A4GHI0 Cluster: Malate dehydrogenase; n=1; uncultured
marine bacterium EB0_35D03|Rep: Malate dehydrogenase -
uncultured marine bacterium EB0_35D03
Length = 335
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/186 (28%), Positives = 87/186 (46%)
Frame = +2
Query: 65 EVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKAT 244
++ +EA ++LT AK AD LI+A+ G HGL+R+ Y+ +++
Sbjct: 6 QISEKEAWDLAFNALTNNQTSDENAKEVADALINAEFDGQAGHGLSRIPSYVEQVIAGKV 65
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
P IL + VD + + + + G+ + RS+H+G AG
Sbjct: 66 AGKVSPSILSSKGSVIRVDANHGFAFPAISLALSEITKTCKSFGIAAASISRSHHFGQAG 125
Query: 425 YWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
+ + GLIGL F N+ + P + GTNPIA A+P + LV+D++ + VA
Sbjct: 126 RHVERLAEVGLIGLMFGNTPKAIPPWGGTQALFGTNPIAFASPRDSSVPLVIDMSLSKVA 185
Query: 605 MGKVEI 622
GKV +
Sbjct: 186 RGKVMV 191
Score = 33.9 bits (74), Expect = 4.1
Identities = 14/24 (58%), Positives = 16/24 (66%)
Frame = +3
Query: 639 EPLPAGWALGPDGKTTTDAKLAFE 710
E +P WA+ DGK TTDAK A E
Sbjct: 197 EKIPEDWAIDKDGKPTTDAKKALE 220
>UniRef50_A0Z6D1 Cluster: Malate/L-lactate dehydrogenase family
protein; n=1; marine gamma proteobacterium HTCC2080|Rep:
Malate/L-lactate dehydrogenase family protein - marine
gamma proteobacterium HTCC2080
Length = 333
Score = 90.2 bits (214), Expect = 4e-17
Identities = 56/182 (30%), Positives = 86/182 (47%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
MP + ++ +SL AVGA +A A + A+ G + GL + Y+ +
Sbjct: 1 MPVLSLQAIESLCRESLLAVGASDEQAAIVAAEIAEAEAEGIRNVGLGYIHLYLKHLKVG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
P A+P ++K SAA+ +VD I A+E GV +A +S+ G+
Sbjct: 61 KVKPNAQPSVVKTSAASTVVDADFGFCHHAYMVGEQRLIETAREQGVAMLAIHQSSSAGV 120
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
G++ + +QGL+ L F NSS + K GTNP A AP + LVVD+AT +
Sbjct: 121 LGWFVRRLAQQGLVSLMFANSSKAVAAHGGKVPFFGTNPFAFGAPRGTDEPLVVDMATAS 180
Query: 599 VA 604
A
Sbjct: 181 TA 182
>UniRef50_A3HWQ6 Cluster: Putative dehydrogenase; n=1; Algoriphagus
sp. PR1|Rep: Putative dehydrogenase - Algoriphagus sp.
PR1
Length = 340
Score = 89.8 bits (213), Expect = 6e-17
Identities = 57/180 (31%), Positives = 82/180 (45%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
+E +E L G A A L D G SHG+NR +I+ I +P A
Sbjct: 12 QEIASQLEKQLLKFGFESEAANKCAALFAKTDLDGVRSHGVNRFPLFIDFIKKGLVNPSA 71
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
P I DG G +F M AI + E G+G VA + +NH+ G +
Sbjct: 72 SPKIESSLGVFERYDGQLGPGNLNASFAMSRAIEISSEFGIGCVALKNTNHWMRGGTYGW 131
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
+A + G IGL FTN+ + LG NP+ +A P KNG +++D+A + A GK+
Sbjct: 132 QAVESGKIGLCFTNTKANMPAWGGSEPKLGNNPLIIAIPRKNGP-VILDMAMSQFAYGKL 190
>UniRef50_A2SP37 Cluster: L-sulfolactate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: L-sulfolactate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 365
Score = 89.4 bits (212), Expect = 8e-17
Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Frame = +2
Query: 56 VMPEVLVE--EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDI 229
++ +VLV+ E R + AVG A A++++ AD G SHG+ Y+ I
Sbjct: 5 IIKKVLVDSGELRMKVAGLFQAVGVSPEHADQIAEVVVFADLRGVESHGVQFTPRYVRGI 64
Query: 230 LSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNH 409
+P ++ A A+VD + LG M A+ A E G G VA R SNH
Sbjct: 65 ARGHLNPKPDIRVVHRRGAVAVVDADNGLGFLSARRAMKEAMAIAAEHGSGSVAVRNSNH 124
Query: 410 YGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLA 589
+G A ++ + A + G+IG + T+ P V S+ L +P+ A P G +VVD A
Sbjct: 125 FGPAAFYPMMALEAGMIGYATTDGPPHTVVWGSRRPVLSNDPVGWAFPTLEGLPIVVDTA 184
Query: 590 TTAVAMGKVEIQVHKRGAV-ASW 655
T V K+ + + G + A W
Sbjct: 185 FTGV-KEKIRLAAQRGGTIPADW 206
Score = 37.5 bits (83), Expect = 0.33
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +3
Query: 612 KLKYKYTKEEPLPAGWALGPDGKTTTDAKLAFE 710
K++ + +PA WA+GPDG TTD K+A E
Sbjct: 191 KIRLAAQRGGTIPADWAVGPDGNPTTDPKVALE 223
>UniRef50_Q8UIX7 Cluster: Malate dehydrogenase; n=2;
Rhizobiales|Rep: Malate dehydrogenase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 346
Score = 87.4 bits (207), Expect = 3e-16
Identities = 49/181 (27%), Positives = 78/181 (43%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
+ EA + G A++ A L+ ++ G HG R+ Y+ D
Sbjct: 22 IAEAEDLVSSIFERNGVLPQNARSVAKALVASEAAGQGGHGFRRIPVYVRQARVGKVDGQ 81
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
A+PV+ + +D + ++ A++ G+ A RS+H G+
Sbjct: 82 ARPVVRRVKPGVLSIDANHGYAYPAIDCALEELPEMARQQGIALAAIHRSHHAGVMALTV 141
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGK 613
+ + GL+ L F N+ + P T GTNPIA AAP D LV+DLA + VA GK
Sbjct: 142 ERFAEMGLVALMFANAPASMAPWGGHTPLYGTNPIAFAAPIGGADPLVIDLALSKVARGK 201
Query: 614 V 616
+
Sbjct: 202 I 202
>UniRef50_Q5PLN6 Cluster: 2,3-diketo-L-gulonate reductase; n=35;
Gammaproteobacteria|Rep: 2,3-diketo-L-gulonate reductase
- Salmonella paratyphi-a
Length = 332
Score = 87.4 bits (207), Expect = 3e-16
Identities = 51/162 (31%), Positives = 83/162 (51%)
Frame = +2
Query: 137 AKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALVDGCDAL 316
A A A++ G YSHG+NR +I + + P AKP + A D A+
Sbjct: 26 ADACAEMFARTTESGVYSHGVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAI 85
Query: 317 GATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSPILV 496
G MD AI A + G+G VA R +NH+ G + +A ++G IG+ +TNS ++
Sbjct: 86 GNLTAKKMMDRAIELASDHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMP 145
Query: 497 PTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
P +K +GTNP+ +A P+ +VD++ + + G +E+
Sbjct: 146 PWGAKECRIGTNPLIVAIPST--PITMVDMSMSMFSYGMLEV 185
>UniRef50_A3SYU7 Cluster: Malate/L-lactate dehydrogenase; n=2;
Sulfitobacter|Rep: Malate/L-lactate dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 356
Score = 87.0 bits (206), Expect = 4e-16
Identities = 53/176 (30%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
L G A A L+ A+ GH SHG+ + Y++ IL+ D A ++++
Sbjct: 16 LAHAGQDAGRAAKVAARLVGANLAGHDSHGVGMIPAYVDGILAGQLDAAADIELVQDKGP 75
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
LVDG G V M +AI +AQ ++ R S H G G W + A + G I +
Sbjct: 76 FLLVDGHRGFGHIVAEQAMTLAIDRAQAHHFATLSLRNSFHLGRLGDWGIMAAEAGFICI 135
Query: 467 SFTN---SSPILVPTRSKTSALGTNPIALAAPA-KNGDNLVVDLATTAVAMGKVEI 622
+ N + P++ P + TNP A PA + V+D+AT+ +AMGK +
Sbjct: 136 LYANVQSARPLVAPFGGSDARFVTNPYCTAIPATEKHPMFVLDMATSTIAMGKARV 191
>UniRef50_Q0ART3 Cluster: Malate/L-lactate dehydrogenase; n=1;
Maricaulis maris MCS10|Rep: Malate/L-lactate
dehydrogenase - Maricaulis maris (strain MCS10)
Length = 355
Score = 86.6 bits (205), Expect = 6e-16
Identities = 53/180 (29%), Positives = 86/180 (47%), Gaps = 4/180 (2%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
L GA V +A+ A L+ A+ GH SHG+ L Y I A +L ++
Sbjct: 21 LVRAGARVDDAECVARHLVEANLKGHDSHGVGILPAYAGHIRRGQVCLDADDTVLTDTTV 80
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
VD GA G + A KA+ G+ ++H G G +A +A + GLI +
Sbjct: 81 LLRVDAGGGWGAPAGQRLIHQAGAKAKSGGLAAATLGNAHHLGRIGAYAEQASEAGLISM 140
Query: 467 SF---TNSSPILVPTRSKTSALGTNPIALAAPAKN-GDNLVVDLATTAVAMGKVEIQVHK 634
F T+ +P++ P R + GTNP+ + PA + ++D+AT+ +A+GK + +K
Sbjct: 141 HFVNVTDHAPLVAPYRGSDARFGTNPVCIGFPATDTRPAFLLDIATSQIALGKARVAANK 200
>UniRef50_Q982E2 Cluster: Malate dehydrogenase-like protein; n=8;
Rhizobiales|Rep: Malate dehydrogenase-like protein -
Rhizobium loti (Mesorhizobium loti)
Length = 383
Score = 86.2 bits (204), Expect = 7e-16
Identities = 55/184 (29%), Positives = 87/184 (47%), Gaps = 2/184 (1%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
+ VE F+ + + EA+ A L A+ GH SHG+ R+ YI +
Sbjct: 26 IKVENLIDFIAEVFGHADSSPEEARRIATYLTTANLTGHDSHGVIRVPGYIRWKKIGSVV 85
Query: 248 PCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
P +L ++ + A++DG G TV + + I K ++AG+ VA R + H G G
Sbjct: 86 PNQTVEVLVDTPSLAVLDGKFGYGQTVAPVAVKLGIEKCKKAGLAAVALRNAGHIGRIGD 145
Query: 428 WALKAEKQGLIGLSFTNS--SPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAV 601
WA A GL+ + F N+ S ++ P + T P + P + D +V+D AT+ V
Sbjct: 146 WAEMAAADGLVSVHFVNATDSLLVAPFGGVERRMSTAPYCVGIPRQGHDPIVLDFATSVV 205
Query: 602 AMGK 613
A GK
Sbjct: 206 AEGK 209
>UniRef50_A1SWJ6 Cluster: Malate/L-lactate dehydrogenase; n=4;
Bacteria|Rep: Malate/L-lactate dehydrogenase -
Psychromonas ingrahamii (strain 37)
Length = 339
Score = 85.8 bits (203), Expect = 1e-15
Identities = 57/192 (29%), Positives = 93/192 (48%)
Frame = +2
Query: 47 LSTVMPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYIND 226
+S + + +EE + +L + GA A A A+ + A+ G SHGL R+ YI
Sbjct: 1 MSHLTINLTLEEIYDLAKTALLSQGANEENAAAIANTVTIAERDGAISHGLFRIPGYIVG 60
Query: 227 ILSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSN 406
+ SK A P I + + D + C+ I A++ G+ VA + S+
Sbjct: 61 LQSKKVVGTATPEIEEVTPIIFRCDAKNGYAPLTHEHCLPPLIDAAKKFGLAAVAIQNSH 120
Query: 407 HYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDL 586
H+ K + GLIGL+ + P + P KT GTNP+A + P + +V+D+
Sbjct: 121 HFAALWPEVEKMSEAGLIGLTTVSYLPWVAPAGGKTPIFGTNPMAFSWPRAGKNPVVIDM 180
Query: 587 ATTAVAMGKVEI 622
AT+++AMG+V I
Sbjct: 181 ATSSMAMGEVMI 192
>UniRef50_Q1YYK8 Cluster: L-sulfolactate dehydrogenase; n=2;
Vibrionaceae|Rep: L-sulfolactate dehydrogenase -
Photobacterium profundum 3TCK
Length = 323
Score = 85.4 bits (202), Expect = 1e-15
Identities = 52/185 (28%), Positives = 96/185 (51%)
Frame = +2
Query: 65 EVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKAT 244
+V EA+ + + G +A D+L+ ++ G SHG+ + I SK+
Sbjct: 2 KVTYREAKELLIKKFMSSGLDWHDANWVTDVLVASEQRGDKSHGIKYAKNIIEIANSKSY 61
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
A PVI + A+ A++DG + +G +++AI+KA++ G V+ R SNH
Sbjct: 62 VKLA-PVIHND-ASIAVLDGKNVIGPVAAKQAIEIAIKKAKKYGTAAVSLRSSNHLFSLS 119
Query: 425 YWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
++A + +IG ++SSP + S +GTNP + AP+ + +V+D+++T VA
Sbjct: 120 HYARYIASKNMIGFICSSSSPAMAAPNSSKVTIGTNPFSFGAPSTSAP-IVMDMSSTQVA 178
Query: 605 MGKVE 619
G+++
Sbjct: 179 RGRIK 183
>UniRef50_Q28QF4 Cluster: Malate/L-lactate dehydrogenase; n=5;
Bacteria|Rep: Malate/L-lactate dehydrogenase -
Jannaschia sp. (strain CCS1)
Length = 328
Score = 85.0 bits (201), Expect = 2e-15
Identities = 50/184 (27%), Positives = 86/184 (46%)
Frame = +2
Query: 65 EVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKAT 244
++ + + R+ E +L A GA +A + + A+ G+ GL LE Y + S
Sbjct: 2 QISISDIRQTAEAALLAHGAGPFQAAEVSKAVARAEETGNIICGLYYLESYCTQLASGRV 61
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
D +P + + + + AI A++ G+ + ++ G
Sbjct: 62 DGMVQPEVSQPKQGVVRANARFGFAQPAFARALPQAIAAARDVGIATLTVAHAHTCTSLG 121
Query: 425 YWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
Y+ + GLIG+ FTN+S I+V KT LGTNPIA+ P ++ + D +T+AVA
Sbjct: 122 YFTEQIAAGGLIGIGFTNASAIVVAPGGKTPVLGTNPIAMTIPGEDAPLMHADFSTSAVA 181
Query: 605 MGKV 616
+GK+
Sbjct: 182 LGKI 185
>UniRef50_Q0RXU9 Cluster: Probable malate/L-lactate dehydrogenase;
n=1; Rhodococcus sp. RHA1|Rep: Probable malate/L-lactate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 349
Score = 85.0 bits (201), Expect = 2e-15
Identities = 55/180 (30%), Positives = 83/180 (46%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
E A D L A G + A A+ ++ AD G SHGL RL +Y+ + + P A
Sbjct: 6 EAAVALATDLLAAAGLDRTRAATTAECIVQADLWGIGSHGLLRLPYYLERMQAGGYPPEA 65
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
V + ++ +DG LG ++A + GV V+ S H G G +
Sbjct: 66 DLVTVSDTGPVVALDGGGGLGHWQLWRAAELAAERCATYGVAAVSVGNSGHCGALGIYTR 125
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A G I L+F+N ++ P L T+PIA P++ ++DLAT+AVA GK+
Sbjct: 126 AAIDTGYIALTFSNGPAVMPPWGGNKPLLSTSPIAAGIPSR-PTPAIIDLATSAVARGKI 184
>UniRef50_Q1FH40 Cluster: Malate/L-lactate dehydrogenase; n=2;
Clostridiales|Rep: Malate/L-lactate dehydrogenase -
Clostridium phytofermentans ISDg
Length = 334
Score = 83.8 bits (198), Expect = 4e-15
Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 2/165 (1%)
Frame = +2
Query: 131 SEAKAQADLLIHADTV--GHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALVDG 304
SE KA+ + AD G YSHG+NR I+ I P + DG
Sbjct: 22 SEEKAKLSAKLFADNSLDGVYSHGVNRFPRVISYIEKGYIKPEQTAAKTEAFGCVERWDG 81
Query: 305 CDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSS 484
+G CMD AI ++ G+G +A + +NH+ G + +A G IG+ +TN+
Sbjct: 82 NLGMGNLNAQICMDRAIELSRTHGIGCIAIKNTNHWMRGGAYGWQAANAGCIGICWTNTM 141
Query: 485 PILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVE 619
P + +K +G NP +A P +G ++V D A + + GKVE
Sbjct: 142 PNMPAWGAKDRRIGNNPFIVAIPRSSGAHVVADCAMSQFSYGKVE 186
>UniRef50_A1BBM1 Cluster: Malate/L-lactate dehydrogenase; n=1;
Paracoccus denitrificans PD1222|Rep: Malate/L-lactate
dehydrogenase - Paracoccus denitrificans (strain Pd
1222)
Length = 356
Score = 83.0 bits (196), Expect = 7e-15
Identities = 51/173 (29%), Positives = 79/173 (45%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
LTA G +A+A AD++ A+ SHGL R+E Y+ + + +P A+P + + A
Sbjct: 38 LTANGLSRDQAEAIADIVTRAEADACRSHGLYRVEGYVAGLRAGRVNPTAQPRVRRLRPA 97
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
VDG N I A+E G+ +A R++H+ + GL+
Sbjct: 98 LLQVDGDKGFAPFAANLARPHLIAAARENGIAAMAIARTHHFSALWADLEPLVEAGLVAW 157
Query: 467 SFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQ 625
F + P T +GTNPI P +G + D AT+A A G VE++
Sbjct: 158 CFVVGQCSVAPHGGSTPLMGTNPIGFGWPRPDGAPFIFDFATSAAARGDVELK 210
>UniRef50_UPI0000E470A0 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 246
Score = 82.2 bits (194), Expect = 1e-14
Identities = 50/122 (40%), Positives = 66/122 (54%)
Frame = +2
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
++PV+L E+ +A +DG LGA VG+F + AI KA + G+GWV + G W
Sbjct: 6 SEPVVLHETVGSAWLDGQGCLGAVVGSFAIKKAIEKAAQNGIGWVLI-------ILGLWN 58
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGK 613
K GL +N+ P V SK LGTNPI LAA +GD L+ D A T AM K
Sbjct: 59 GFLCKHVNRGLCMSNTWPASVVPGSKQRVLGTNPICLAAAGLDGDYLLFDSALTVTAMRK 118
Query: 614 VE 619
V+
Sbjct: 119 VK 120
>UniRef50_A1WAI4 Cluster: Malate/L-lactate dehydrogenase; n=18;
Proteobacteria|Rep: Malate/L-lactate dehydrogenase -
Acidovorax sp. (strain JS42)
Length = 350
Score = 82.2 bits (194), Expect = 1e-14
Identities = 52/168 (30%), Positives = 76/168 (45%)
Frame = +2
Query: 119 GAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALV 298
G A A A+ G +SHG+ R+ Y++ + S D A P + + V
Sbjct: 31 GTSAEVAAVLAHNCASAERDGAHSHGVFRIPGYLSTLASGWVDGRAVPRVEDVAPGYLAV 90
Query: 299 DGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTN 478
D + + KA+ GV +A R S+H+ GL+ L+ N
Sbjct: 91 DAGNGFAQPAYRAAYSALVAKARANGVALLAIRNSHHFAALWPDVEPLADDGLVALALVN 150
Query: 479 SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
S +VP+ T+ GTNPIA AAP + LV DLAT+A+A G V+I
Sbjct: 151 SMACVVPSGGTTALFGTNPIAFAAPRAGHEPLVFDLATSAIAHGDVQI 198
>UniRef50_Q1YQC0 Cluster: Hypothetical oxidoreductase yiaK; n=1;
gamma proteobacterium HTCC2207|Rep: Hypothetical
oxidoreductase yiaK - gamma proteobacterium HTCC2207
Length = 340
Score = 79.8 bits (188), Expect = 6e-14
Identities = 52/181 (28%), Positives = 80/181 (44%)
Frame = +2
Query: 80 EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAK 259
E ++ +E L A G A+A + A+ G SHGL R+ YI + S + A
Sbjct: 10 EIQQLVEQCLIANGCNTDNAEALGRTIASAERDGSASHGLFRMPGYIASLRSGKVNGNAN 69
Query: 260 PVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
P + + S A VDG I A+E G+ +A +H+
Sbjct: 70 PTVTRISPAVVKVDGDHGYAPLALEKGRAALIEAARENGIAAMALVNVHHFASLWVEVEP 129
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVE 619
+ GL+ ++FT P +VP +KT GTNP+ P + LV D A+ ++A G+V
Sbjct: 130 IAEAGLVAMAFTTYKPAVVPAGAKTPLFGTNPMCFGWPRGDKPPLVFDQASASMARGEVM 189
Query: 620 I 622
I
Sbjct: 190 I 190
>UniRef50_Q11D61 Cluster: Malate/L-lactate dehydrogenase; n=1;
Mesorhizobium sp. BNC1|Rep: Malate/L-lactate
dehydrogenase - Mesorhizobium sp. (strain BNC1)
Length = 360
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/181 (29%), Positives = 83/181 (45%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
VE AR +L G V EAK L+ G+ GLNR I + +A +P
Sbjct: 25 VEGARDLTRRALVGAGYSVEEAKIIQSQLVTNALDGYGPAGLNRALAIIME--PRAREPR 82
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
I+ E+ +AL+DG + +G +VA+ KA+ G V G ++
Sbjct: 83 RAIRIVHETPNSALLDGGNNVGYLACWRASEVALEKARATGFAVVGVNNCPFSGRNAHYV 142
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGK 613
+ G + L T+ P ++P + + +GTNPI A P K D ++VD++T A+ G
Sbjct: 143 EPLARAGFVALHTTSGMPHVLPLGGRKAVMGTNPICFAFPTKGRDPIIVDMSTLAIMWGD 202
Query: 614 V 616
V
Sbjct: 203 V 203
>UniRef50_A3K6M0 Cluster: Malate/L-lactate dehydrogenase family
protein; n=1; Sagittula stellata E-37|Rep:
Malate/L-lactate dehydrogenase family protein -
Sagittula stellata E-37
Length = 335
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/172 (30%), Positives = 77/172 (44%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
LT G + A+A A L SHGL RL + + D A+P I+ + +A
Sbjct: 19 LTRTGYGEAHARAIASFLTTCQMDDCGSHGLFRLFMCVETMRRGTIDGTAEPDIVTDDSA 78
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
D + + + I +A+ GV +A R H+ + ++GL L
Sbjct: 79 VVRADARGGISLLATQSGLPLLIERARRFGVAALAVNRCYHFSALWPEVEQLAREGLSAL 138
Query: 467 SFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEI 622
S S + P ALGTNPIA A P + D LV DLAT+A A G++E+
Sbjct: 139 SMVPSHAWVAPAGGTRGALGTNPIAFAWPRGDTDPLVFDLATSAFARGEIEL 190
>UniRef50_Q5DB34 Cluster: SJCHGC06758 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06758 protein - Schistosoma
japonicum (Blood fluke)
Length = 232
Score = 78.2 bits (184), Expect = 2e-13
Identities = 37/68 (54%), Positives = 55/68 (80%), Gaps = 1/68 (1%)
Frame = +2
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAK-NGDNLVVDLATTAVAMGKV 616
A ++GLIGL+FTN+SP++ PTR++ A+GTNP+ LAAP K D+ V+D+AT+AVA+GK+
Sbjct: 2 ALQEGLIGLAFTNTSPLVFPTRARKLAVGTNPLTLAAPGKVPDDHFVLDMATSAVALGKI 61
Query: 617 EIQVHKRG 640
E+ +RG
Sbjct: 62 EMN-RRRG 68
>UniRef50_A3YAI3 Cluster: Malate/L-lactate dehydrogenase family
protein; n=5; Proteobacteria|Rep: Malate/L-lactate
dehydrogenase family protein - Marinomonas sp. MED121
Length = 332
Score = 77.0 bits (181), Expect = 4e-13
Identities = 55/186 (29%), Positives = 90/186 (48%), Gaps = 3/186 (1%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
++E + +L A GA A A + A++VG+ GL LE Y + +
Sbjct: 10 LDEIEQKTAQALIAHGAANWVAVEVAKAVRQAESVGNMICGLFYLESYCTQLKTGRVKGD 69
Query: 254 AKPVILKESAATALVDGCDALGATVGNFC--MDVAIRKAQEAGVGWVAARRSNHYGMAGY 427
P++ + ++ VD LG F + AI A+E G+ +A R S+ GY
Sbjct: 70 VDPIVSQPKSSAIEVDA--QLGFAQAAFAKGFEKAISVAKENGIASLAIRHSHTCTSMGY 127
Query: 428 WALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGD-NLVVDLATTAVA 604
+ + GLI + TN+ + P + LGTNPI++A PAK+G + D +T+A+A
Sbjct: 128 FTEQIANAGLIAVGMTNAPACVSPPGGSKAVLGTNPISMAVPAKDGGISFKFDQSTSAIA 187
Query: 605 MGKVEI 622
+GK+ I
Sbjct: 188 IGKIRI 193
>UniRef50_A3XSZ7 Cluster: Hypothetical oxidoreductase yiaK; n=1;
Vibrio sp. MED222|Rep: Hypothetical oxidoreductase yiaK
- Vibrio sp. MED222
Length = 333
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 1/188 (0%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
MP V E+ ++ E L A A A + G YSHG+NR +I+ +
Sbjct: 1 MPLVSTEKLQQEYERILLARDMKPEMATKLAAGFVEMANEGTYSHGINRFPVFIDQVDKG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
A+P + A D G G C + A+ A++ G+G V R SNH+
Sbjct: 61 QIKLNAEPECVNSMGALEQWDCNYGPGVLNGLICAERAMELARDYGIGMVGMRNSNHWMR 120
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGD-NLVVDLATT 595
G + LK ++G G++ TNS ++ K +G+NP+ +A GD +VVD + +
Sbjct: 121 GGAYVLKMAREGFAGIASTNSIAVMPAWGGKDHRVGSNPLIMAVA---GDPPVVVDCSMS 177
Query: 596 AVAMGKVE 619
+ G+++
Sbjct: 178 QFSYGQLQ 185
>UniRef50_Q1GLV8 Cluster: Malate/L-lactate dehydrogenase; n=5;
Rhodobacteraceae|Rep: Malate/L-lactate dehydrogenase -
Silicibacter sp. (strain TM1040)
Length = 344
Score = 74.9 bits (176), Expect = 2e-12
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 1/196 (0%)
Frame = +2
Query: 53 TVMPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDIL 232
T + + E D+L A G + A+ A + G SHGL + Y +
Sbjct: 11 TATETLTLSEIESLAFDALVAAGTSPANARPLAVATAMTEADGVASHGLAYIPIYAQHVE 70
Query: 233 SKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHY 412
D A P + A VD + + I A+E GV +A S +
Sbjct: 71 CGKVDGQANPKVAHPRPAVITVDAATGFAHRAIDLGFEQLIPLAKEMGVAVLAVNNSYNC 130
Query: 413 GMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGD-NLVVDLA 589
G+ G + + GL+G FTN+ + P+ +GTNP +++AP +G L++D +
Sbjct: 131 GVLGVHTQRLAQAGLMGFGFTNAPASIAPSGGAKPVVGTNPFSISAPGSDGTAALLIDQS 190
Query: 590 TTAVAMGKVEIQVHKR 637
+ +A K E+ H R
Sbjct: 191 ASTIA--KSEVMKHAR 204
>UniRef50_Q3S8E9 Cluster: Putative malate/L-lactate dehydrogenase;
n=1; Paracoccus pantotrophus|Rep: Putative
malate/L-lactate dehydrogenase - Paracoccus pantotrophus
(Thiosphaera pantotropha)
Length = 359
Score = 74.5 bits (175), Expect = 2e-12
Identities = 46/185 (24%), Positives = 92/185 (49%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
M ++ ++EAR +E + A G EA A AD L+ + G GL+R + D ++
Sbjct: 30 MAKIAIDEARVLVERVMEATGYGAPEAAAIADHLLDCELRGVAMGGLSRA-ISVADHFAQ 88
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
I +E+ +A ++G + +G +G ++AI KA+ +G+G V + GM
Sbjct: 89 HRGRIDTLRIQRETPFSAALEGGNRVGYLLGAKATEIAIEKARASGIGMVTGHCAIFSGM 148
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
Y+ + G + ++ ++ P++ P + GTNPIA P+ + + ++ D+ T+
Sbjct: 149 LSYYVERITAAGFVAVATSSVGPMVAPEGGTEALFGTNPIAFGFPSAS-EPVIWDIGTSR 207
Query: 599 VAMGK 613
+ + +
Sbjct: 208 IMLAE 212
>UniRef50_A1WRH9 Cluster: Malate/L-lactate dehydrogenase; n=2;
Burkholderiales|Rep: Malate/L-lactate dehydrogenase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 354
Score = 72.9 bits (171), Expect = 7e-12
Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 2/189 (1%)
Frame = +2
Query: 80 EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAK 259
E R+F L G P++ A A A L+ D +GH +HGL L Y+ ++ A +
Sbjct: 11 ELRQFSTQLLQKAGLPLAPADAVARTLVDGDLLGHDTHGLALLVPYVREVSKGAMTTSGE 70
Query: 260 PVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
P ++ + A + +G G + + +D I +A+E G + S+H + L+
Sbjct: 71 PDVVSDRPAALVWNGRRLPGPWLVHKGIDALIARARELGTAALVIHHSHHIACLAAYLLR 130
Query: 440 AEKQG-LIGLSFTNSSPILVPTRSKTSALGT-NPIALAAPAKNGDNLVVDLATTAVAMGK 613
A ++G L+ LS ++ + V T A+ T NPIA P +G L+VD++ + G
Sbjct: 131 ATEEGFLMVLSSSDPAVQSVAPFGGTRAVFTPNPIAAGIPT-SGTPLLVDISASITTNG- 188
Query: 614 VEIQVHKRG 640
+ ++HK G
Sbjct: 189 MSNRLHKAG 197
>UniRef50_A4SB62 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 330
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/179 (30%), Positives = 86/179 (48%), Gaps = 2/179 (1%)
Frame = +2
Query: 68 VLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
V +EE + ++ +G +AK D+L++A G+ + G+ ++ N + A
Sbjct: 2 VPIEELKTTTTKAIRGIGYNEKDAKVILDVLMYAQLRGN-NQGI--IKVTTNGL---AMA 55
Query: 248 PCAKP-VILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAA-RRSNHYGMA 421
P A+P V+ E+ +A +DG G V VA KA+E G G V S G
Sbjct: 56 PDAEPMVVTHETKLSAAIDGKKTQGMLVLAEATRVAHEKAKEHGFGIVGTCNTSTSTGAL 115
Query: 422 GYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
GY+ QG+I + F S + P S + GTNPI + P+ G +V+D+AT+A
Sbjct: 116 GYYCKSVADQGMISICFAQSPEFVAPAGSSKAIFGTNPIGVGIPSSEG-AMVLDMATSA 173
>UniRef50_Q5QTW6 Cluster: Malate/L-lactate dehydrogenase family
enzyme; n=2; Idiomarina|Rep: Malate/L-lactate
dehydrogenase family enzyme - Idiomarina loihiensis
Length = 356
Score = 70.9 bits (166), Expect = 3e-11
Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 3/173 (1%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
LT GA A+ + L+ D +G +HGL RL + + +PV+L+E AA
Sbjct: 21 LTEAGASGEVARNVSYYLLEGDLLGFSTHGLIRLLNNCQWLRDGKSLAKGQPVVLRERAA 80
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
A D G V +D A + A++AG G V RRS H + A QGL+ +
Sbjct: 81 VANWDAQFLPGPYVVPQAIDAACKMAKQAGTGTVVVRRSQHVAALAAYLSIATDQGLV-V 139
Query: 467 SFTNSSP---ILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
S S+P + P K + NP A+ P+ N + L+ D++ + A GKV
Sbjct: 140 SLMCSTPGQRAVAPFGGKEAVFSPNPFAVGVPSSN-NPLLFDISFSMTAAGKV 191
>UniRef50_Q125C6 Cluster: Malate/L-lactate dehydrogenase; n=1;
Polaromonas sp. JS666|Rep: Malate/L-lactate
dehydrogenase - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 353
Score = 70.1 bits (164), Expect = 5e-11
Identities = 45/180 (25%), Positives = 82/180 (45%), Gaps = 3/180 (1%)
Frame = +2
Query: 89 RFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVI 268
RF LTA G P ++A A LL+ D + ++HG+ YI+ + + +P +
Sbjct: 14 RFASQLLTAAGLPAAKADTVARLLVLTDMMQRHTHGVALCPLYIDQLKNGLMGTDGEPEV 73
Query: 269 LKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEK 448
++++ AT + DG G + + + +A + + GV A RRS+H +A
Sbjct: 74 VRDTGATVVWDGHYLPGLWLVDKALSLAFERVAQHGVVTFAMRRSHHIACLAALVKQATD 133
Query: 449 QGLIGLSFTN--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLV-VDLATTAVAMGKVE 619
+GL+ + T+ + P + L NP A+ P LV + + T V+M + +
Sbjct: 134 RGLVAILATSDPGGKFVAPFGGRDPVLTPNPFAIGYPGSKAPVLVDICASITTVSMARTK 193
>UniRef50_Q98CD3 Cluster: Mll5197 protein; n=1; Mesorhizobium
loti|Rep: Mll5197 protein - Rhizobium loti
(Mesorhizobium loti)
Length = 333
Score = 69.7 bits (163), Expect = 7e-11
Identities = 48/180 (26%), Positives = 85/180 (47%)
Frame = +2
Query: 65 EVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKAT 244
++ +++AR + GA A++ +I A+ G + GL+ Y+ + +
Sbjct: 2 QLSLDQARGLCRMAALGAGANEEAAQSLTASIIAAEAEGLSTVGLSHFIDYLEALEAGRI 61
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
D A PVI + + A L D L T + +D + A+ GV + + + G G
Sbjct: 62 DGNADPVITRPALAVYLSDARGGLAHTGFDRTIDDLAKAAKLFGVAIFSQKNAYTCGALG 121
Query: 425 YWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
Y+ + QGL+ + TN +L + S TNP++ AAPA +G LV+D +++A A
Sbjct: 122 YFTGRLAAQGLVSFAATNGPAVLAGSGSVKPVYCTNPMSFAAPAADGAPLVIDQSSSATA 181
>UniRef50_A6VRA6 Cluster: Malate/L-lactate dehydrogenase; n=1;
Marinomonas sp. MWYL1|Rep: Malate/L-lactate
dehydrogenase - Marinomonas sp. MWYL1
Length = 349
Score = 69.7 bits (163), Expect = 7e-11
Identities = 45/172 (26%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Frame = +2
Query: 107 LTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAA 286
L+ G P A A+LLI +D +G +HGL+ + +YI ++ + V++ ++ +
Sbjct: 19 LSQYGMPDDRASITAELLIQSDELGFTTHGLSLIPYYIPELQAGKMQEADDVVVVNDTGS 78
Query: 287 TALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGL 466
T + + G + N MD A + +E GV + R++H G + A + LI +
Sbjct: 79 TFVWNAQYLPGIWMMNKAMDEAFSRVKEHGVVTASINRAHHIGCLSTYVKLATDKNLICI 138
Query: 467 SFTN--SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
T+ + ++ P L NP A+ P NGD +++D T+ KV
Sbjct: 139 VSTSDPAGKLVAPFGGIDPVLTPNPWAIGYPT-NGDPVIIDTVTSICTFSKV 189
>UniRef50_Q1QWQ4 Cluster: Malate/L-lactate dehydrogenase; n=4;
Gammaproteobacteria|Rep: Malate/L-lactate dehydrogenase
- Chromohalobacter salexigens (strain DSM 3043 / ATCC
BAA-138 / NCIMB13768)
Length = 355
Score = 69.3 bits (162), Expect = 9e-11
Identities = 48/183 (26%), Positives = 91/183 (49%), Gaps = 9/183 (4%)
Frame = +2
Query: 95 MEDSLTAV----GAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA-- 256
+ D LTA+ GA A+ A +L+ D +GH++HG+ + Y+ND+ KA + C
Sbjct: 9 LTDLLTALFAEAGATAEVAETTASILVEGDLLGHHTHGVKLAKGYLNDL--KAGNACGDH 66
Query: 257 KPVILKESA-ATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
+ + L ES+ A++DG LG + + A + A G+G V +RS+H +
Sbjct: 67 RQLALTESSPVAAMIDGHYVLGPYLVTRALAHARQAADGFGIGIVTLKRSHHIACLAAYL 126
Query: 434 LKAEKQGLIGLSFTNSSPI--LVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+QGL+ + ++ + + P T +P+A+ P + L++D++ +++
Sbjct: 127 RPLVEQGLVPIVLSSDPAVASVAPYGGTTPVYTPDPLAIGIPGRE-HPLLIDVSMSSITN 185
Query: 608 GKV 616
G V
Sbjct: 186 GTV 188
>UniRef50_Q1R3L9 Cluster: Putative lactate dehydrogenase; n=6;
Enterobacteriaceae|Rep: Putative lactate dehydrogenase -
Escherichia coli (strain UTI89 / UPEC)
Length = 403
Score = 68.1 bits (159), Expect = 2e-10
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 4/194 (2%)
Frame = +2
Query: 53 TVMPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDIL 232
T+ ++ VE+ R L G A+ A+ +I A+ G SHG+ L Y+ +I
Sbjct: 46 TMSLQIAVEKVRWLAAGLLELNGCDADIAQDVAEHMIEAERYGFASHGVTLLPKYLENIA 105
Query: 233 SKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHY 412
A+P L + G G ++ AI +A+ G + ++H
Sbjct: 106 RGDVTANARPECLTSEGNLQRFHAHNGFGQHAGKVAVNAAIEQAKHRGFCLLTLCHAHHL 165
Query: 413 GMAGYWALKAEKQGLIGLSFTN--SSPILV-PTRSKTSALGTNPIALAAPAKNG-DNLVV 580
G G++ QGL L+ +N P LV P + TNP A P +G ++V
Sbjct: 166 GRMGHYGQMVADQGLAMLAMSNVTGRPALVAPWGGAEPRMTTNPFCFAWPFSDGRPPILV 225
Query: 581 DLATTAVAMGKVEI 622
D AT+++A+ K +
Sbjct: 226 DFATSSMALNKARV 239
>UniRef50_Q4KAT3 Cluster: Malate/L-lactate dehydrogenase family
protein; n=1; Pseudomonas fluorescens Pf-5|Rep:
Malate/L-lactate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 334
Score = 67.7 bits (158), Expect = 3e-10
Identities = 45/175 (25%), Positives = 73/175 (41%)
Frame = +2
Query: 80 EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAK 259
EAR F + G+ A+A A+ + A G S G L Y++ S AK
Sbjct: 14 EARDFAQRCCLQAGSSQEVAQALAEATVSAQGHGLASVGFEHLADYLHGFASGRIAGLAK 73
Query: 260 PVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
P+I + + A D + + ++ G+ A G GY+ +
Sbjct: 74 PLITQVAPAMIRCDARAGIAQLGFDQAFGAVCDSTRQLGISLFALHNGFTCGELGYYTRR 133
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
+GL+ L+F N +L + TNP+A AAP +G L++D A++A A
Sbjct: 134 LAAEGLVALAFCNGPALLTVAGQRQPIYSTNPLAFAAPCGDGRLLLIDQASSATA 188
>UniRef50_Q1YHD0 Cluster: Putative malate/L-lactate dehydrogenase;
n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
malate/L-lactate dehydrogenase - Aurantimonas sp.
SI85-9A1
Length = 348
Score = 67.7 bits (158), Expect = 3e-10
Identities = 49/192 (25%), Positives = 89/192 (46%), Gaps = 3/192 (1%)
Frame = +2
Query: 92 FMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVIL 271
+ D+L A G A+ A+ L+ D +GH +HGL L Y+ ++ + +P I+
Sbjct: 13 YAHDALAASGLDAGHAEIVAETLVEGDLLGHSTHGLALLPRYLRELEAGHMTKAGEPTIV 72
Query: 272 KESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYG-MAGYW-ALKAE 445
++ A+A G G + + + +A++AGV VA +S+H +A Y A+ E
Sbjct: 73 RDHGASAAWGGNYLPGPVLVRRALALCTDRARDAGVATVAIGQSHHVACLAAYLKAVTDE 132
Query: 446 KQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQ 625
I S + ++ + P + NPIA P GD ++VD++ + V +
Sbjct: 133 GMAAIIASSSPATASVAPFGAVEGIYSPNPIAAGWPT-GGDPVLVDISASITTNSLVSER 191
Query: 626 VHK-RGAVASWL 658
V + R +W+
Sbjct: 192 VEEGRRLPGAWM 203
>UniRef50_A4YFT2 Cluster: Malate/L-lactate dehydrogenase; n=1;
Metallosphaera sedula DSM 5348|Rep: Malate/L-lactate
dehydrogenase - Metallosphaera sedula DSM 5348
Length = 328
Score = 66.9 bits (156), Expect = 5e-10
Identities = 39/171 (22%), Positives = 83/171 (48%)
Frame = +2
Query: 128 VSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALVDGC 307
V ++ AD ++ A+ GH SHG+ RL + + + +LK+ + +DG
Sbjct: 27 VEGSEVIADHMVEAELRGHSSHGVQRLIPLVKGVELGTISRRLQYDVLKKERGSMWIDGK 86
Query: 308 DALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSP 487
++G + N + + +A + ++H G GY+ K +G +G+ F N+ P
Sbjct: 87 HSVGIVLWNQLIQHEFDEPSSV----IAVKNASHIGFLGYYTDKLATRGYVGIMFGNAEP 142
Query: 488 ILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQVHKRG 640
+V + L T P+++ P + +V+D+A ++ + GK+ ++ ++G
Sbjct: 143 AVVLPGTSRKLLSTTPLSIGIP--HAPPIVLDMALSSTSRGKI-LEAQRKG 190
Score = 35.9 bits (79), Expect = 1.0
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 633 KEEPLPAGWALGPDGKTTTDAKLA 704
K EP+P GWA+ +GK TTD +LA
Sbjct: 189 KGEPIPEGWAVDSEGKPTTDPELA 212
>UniRef50_A3JKA4 Cluster: Probable L-malate dehydrogenase; n=1;
Marinobacter sp. ELB17|Rep: Probable L-malate
dehydrogenase - Marinobacter sp. ELB17
Length = 340
Score = 66.5 bits (155), Expect = 6e-10
Identities = 50/187 (26%), Positives = 76/187 (40%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
EEA L G ++A ++ +I G SHGL R+ IN + S P A
Sbjct: 11 EEALSLSRKILLKKGFSDDFSRAISETVIAGQKDGCASHGLYRILGCINTLASGGVVPDA 70
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
+P I S V+ + + + I K +E G+ +A H+
Sbjct: 71 EPHIEPSSGGIVKVNANGGFSQLAFSLGLPLLIEKTKENGIALLAINHCVHFSALWIEVE 130
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
+ K+GL+ + + + P LGTNP A P V D AT+A+A G V
Sbjct: 131 QITKRGLVAIVCNPTQAYVAPHGGSRPLLGTNPFAFGWPRPGNLPFVFDFATSAIARGDV 190
Query: 617 EIQVHKR 637
E+ H+R
Sbjct: 191 EL--HER 195
>UniRef50_Q9I492 Cluster: Uncharacterized oxidoreductase PA1252;
n=43; cellular organisms|Rep: Uncharacterized
oxidoreductase PA1252 - Pseudomonas aeruginosa
Length = 334
Score = 65.7 bits (153), Expect = 1e-09
Identities = 53/201 (26%), Positives = 81/201 (40%)
Frame = +2
Query: 59 MPEVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSK 238
M + ++E R L + +A AD L+ + SHG+ RL I + +
Sbjct: 1 MIRMTLDEVRELAVRILRRHAFSEAHVQAVADTLVAGERDECASHGIWRLLGCIATLKAG 60
Query: 239 ATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGM 418
A+P + + VD + + KA+ G+ +A R H+
Sbjct: 61 KVSADAEPELHDIAPGLLRVDAHGGFSQCAFRLGLPHLLEKARSQGIAAMAVNRCVHFSA 120
Query: 419 AGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTA 598
+ GL+ L+ T S + P + GTNPIA P +G V D AT+A
Sbjct: 121 LWVEVEALTEAGLVALATTPSHAWVAPAGGRKPIFGTNPIAFGWPRPDGPPFVFDFATSA 180
Query: 599 VAMGKVEIQVHKRGAVASWLG 661
VA G EIQ+H+R LG
Sbjct: 181 VARG--EIQLHERAGKPIPLG 199
>UniRef50_Q8YB95 Cluster: MALATE DEHYDROGENASE; n=11;
Alphaproteobacteria|Rep: MALATE DEHYDROGENASE - Brucella
melitensis
Length = 345
Score = 64.5 bits (150), Expect = 3e-09
Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 1/189 (0%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
+E+ +E+ G +A A A +++ + SHG+ R+E + + + P
Sbjct: 9 IEKLHARVEEIFRKAGLNAIQAGAVARVIVAGERDHCKSHGIYRIEGALRTVKAGKVKPD 68
Query: 254 AKP-VILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYW 430
A P ++ +E++A VD + V +A+ G+ + H+
Sbjct: 69 AVPELVAQEASAIVRVDAKGGFANPAFELGVPVLAERARSHGLAALVINDCTHFSALWPE 128
Query: 431 ALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMG 610
++GL GL S + PT LGTNP A P ++ V D AT+ A G
Sbjct: 129 VEALTEKGLAGLVMCPSYATVAPTGGSKPLLGTNPFAFGWPRRDNPPYVFDFATSVAARG 188
Query: 611 KVEIQVHKR 637
EI++H+R
Sbjct: 189 --EIELHRR 195
Score = 32.7 bits (71), Expect = 9.5
Identities = 13/22 (59%), Positives = 15/22 (68%)
Frame = +3
Query: 645 LPAGWALGPDGKTTTDAKLAFE 710
LP GWA+ DGK TTD + A E
Sbjct: 200 LPEGWAIDKDGKPTTDPETALE 221
>UniRef50_Q11CF6 Cluster: Malate/L-lactate dehydrogenase; n=1;
Mesorhizobium sp. BNC1|Rep: Malate/L-lactate
dehydrogenase - Mesorhizobium sp. (strain BNC1)
Length = 358
Score = 63.3 bits (147), Expect = 6e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 3/169 (1%)
Frame = +2
Query: 119 GAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALV 298
G P +A A +L+ D G +HGL L Y+ DI + P +L + A
Sbjct: 29 GMPAEKASDVAAVLVEGDLFGKSTHGLALLPLYLRDIEAGGMTLDGDPEVLNDLGACLTW 88
Query: 299 DGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQG---LIGLS 469
DG G + A+ +A+ G+G VA +RS+H G + A G L+ L+
Sbjct: 89 DGRKLPGPWLLRRATAEALSRAKRFGLGAVAIQRSHHTACLGAYLEPAVAAGCMVLVTLT 148
Query: 470 FTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
S + P T L +NPIA AP+ + +++D++T + G V
Sbjct: 149 DPGHSSV-APFGGVTPVLTSNPIAFGAPSPDRP-ILIDMSTALMTNGGV 195
>UniRef50_Q11B93 Cluster: Malate/L-lactate dehydrogenase; n=1;
Mesorhizobium sp. BNC1|Rep: Malate/L-lactate
dehydrogenase - Mesorhizobium sp. (strain BNC1)
Length = 354
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/175 (26%), Positives = 79/175 (45%), Gaps = 2/175 (1%)
Frame = +2
Query: 92 FMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVIL 271
+ + L A+ A+ AD+L+ D +GH +HGL +L Y++++ P ++
Sbjct: 15 YARNLLKALDVQTDIAEVVADVLVEGDLLGHSTHGLAQLPSYLDNLAKGQMKPSGTYSVV 74
Query: 272 KESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYG-MAGYW-ALKAE 445
+ A DG G + A +A++ G G V RRS+H +A Y L AE
Sbjct: 75 SDFPAATTWDGQWLPGPWLTRTACIEAKTRARKFGTGTVVIRRSHHIACLAAYLEPLTAE 134
Query: 446 KQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMG 610
I S + + P L NP+A+ P K GD +++D++ + +G
Sbjct: 135 GFVCIIQSSDPAVKAVAPHGGTRPFLTPNPVAVGIPTK-GDPILIDVSMSIATVG 188
>UniRef50_Q92YR7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putative
- Rhizobium meliloti (Sinorhizobium meliloti)
Length = 334
Score = 60.9 bits (141), Expect = 3e-08
Identities = 48/176 (27%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
EE ++LT GA A+A A + A+ G+ GL L + + D A
Sbjct: 9 EEIEAVCLEALTLHGAAAETARAVAGAITRAEADGNRVCGLYYLPIFCRHLAIGKVDGEA 68
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
P + T VD I A++AG+ +A R S + G+
Sbjct: 69 VPEVTTRGV-TVTVDARSGFAHPAIAAGTPALIDLARQAGLAAMAVRNSYNCLALGHHVR 127
Query: 437 KAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNG-DNLVVDLATTAV 601
GLIG+ +N+ + P + + GTNP+A A P+K G +VVD + +AV
Sbjct: 128 PLADAGLIGICVSNAPASVAPPGATRALFGTNPLAFAVPSKEGAPTIVVDQSMSAV 183
>UniRef50_Q5ARM7 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 230
Score = 60.5 bits (140), Expect = 4e-08
Identities = 30/83 (36%), Positives = 48/83 (57%)
Frame = +2
Query: 341 MDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSA 520
M AI++A+ G+G V+ SNH+GMA + L+A + +I L FT+S+ + P K +
Sbjct: 1 MAEAIKRAEIYGIGMVSVNHSNHFGMAATYVLQALQANMISLVFTSSAKQMPPFGGKETP 60
Query: 521 LGTNPIALAAPAKNGDNLVVDLA 589
LG P A AP+ ++D+A
Sbjct: 61 LGIAPFAAGAPSNREVPYILDIA 83
>UniRef50_Q96YT3 Cluster: 318aa long hypothetical malate
dehydrogenase; n=1; Sulfolobus tokodaii|Rep: 318aa long
hypothetical malate dehydrogenase - Sulfolobus tokodaii
Length = 318
Score = 58.4 bits (135), Expect = 2e-07
Identities = 48/193 (24%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = +2
Query: 65 EVLVEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKAT 244
++ V+EA +E L G V A + A+ GHYSHGL R+ + I
Sbjct: 2 KIKVKEAESLVESILKKRG--VENPSIIAKHFVEAELRGHYSHGLQRVIPLVKGIDLGTI 59
Query: 245 DPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAG 424
+ +K L D ++G V ++ + +E +A R S+H G G
Sbjct: 60 RKTVQLTEIKREDNAVLYDANYSIGILVWHYLTE----SPKET---LIAVRNSSHIGFLG 112
Query: 425 YWALK-AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAV 601
Y+ + A + G + N+ P +V + + T PI++A P + +V+D++ + +
Sbjct: 113 YYTRRIAMRLGKPAIMIGNAEPAVVKPGTAKKIISTTPISIAIPCEK--IVVLDMSLSPI 170
Query: 602 AMGKVEIQVHKRG 640
A GK+ I+ ++G
Sbjct: 171 ARGKI-IEAKRKG 182
>UniRef50_Q46QD8 Cluster: Malate/L-lactate dehydrogenase; n=4;
Burkholderiales|Rep: Malate/L-lactate dehydrogenase -
Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 352
Score = 57.6 bits (133), Expect = 3e-07
Identities = 39/166 (23%), Positives = 71/166 (42%)
Frame = +2
Query: 119 GAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALV 298
G A A L+ ++ G+ +HG+ R+ Y++ + + +P A + + A ++
Sbjct: 22 GVAPEHAVEAAAALVRSELRGYKTHGMTRVPSYVDRLRAGDFNPRAT-MSHRAFAGGIVL 80
Query: 299 DGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTN 478
D A+G G + + + + + VA + H G G AL A + G +
Sbjct: 81 DADGAMGQVAGPHAVRLGLEALESSASVLVAVQSCGHLGALGIHALLAAEAGAFCMVGQR 140
Query: 479 SSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
+ P+L A+G NPIA P +V D+A + A G +
Sbjct: 141 TPPVLGMEGFSGPAIGHNPIAFGCPLPGQAPIVFDVACSVAARGHI 186
Score = 33.9 bits (74), Expect = 4.1
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +3
Query: 639 EPLPAGWALGPDGKTTTDAKLA 704
+P+P GWAL DG+ TTDA+ A
Sbjct: 194 KPIPEGWALDADGQPTTDAQRA 215
>UniRef50_A7CY20 Cluster: Malate/L-lactate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: Malate/L-lactate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 366
Score = 57.2 bits (132), Expect = 4e-07
Identities = 39/118 (33%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Frame = +2
Query: 281 AATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLI 460
AA + + LG + ++ AIR A + G G V+ + HY G + ++A ++G I
Sbjct: 82 AAAKIWNANKKLGQSTAYRAIEEAIRLADQYGTGTVSVDNAFHYLWGGGYVMEAARRGYI 141
Query: 461 GLSFTNSSPIL---VPTRSKTSALGTNPIALAAPAKN--GDNLVVDLATTAVAMGKVE 619
++TN + L VP K LGTNP + P + G +V+D AT+ VAMG+V+
Sbjct: 142 --AYTNCTAALAEVVPFGGKFPTLGTNPHSWGFPTTDAIGYPIVIDWATSVVAMGRVQ 197
>UniRef50_Q1M4M8 Cluster: Putative L-lactate dehydrogenase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
L-lactate dehydrogenase - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 353
Score = 56.8 bits (131), Expect = 5e-07
Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Frame = +2
Query: 59 MPEVLVEEAR--RFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDIL 232
MP L++ +F + LT G V +A+ A +L+ D +GH +HG++ L +Y+ +
Sbjct: 1 MPMPLIDRIALTQFAKQILTRAGMEVDKAETTAVVLVEGDMIGHETHGVSLLNWYVEALE 60
Query: 233 SKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHY 412
+ ++ + A + DG GA + ++ A + + GV A R +H
Sbjct: 61 DGSLAKSGSYEVVNDRGAAFVWDGKSLPGAWLLTKAIEQACERVGDHGVVTAAIRNCHHT 120
Query: 413 GMAGYWALKAEKQGLI-GLSFTNSSPILVPTRSKTSALGT-NPIALAAPAKNGDNLVVDL 586
+ + +GLI LS ++ + V T L T NP+A P + D +++D+
Sbjct: 121 CALSAFMRQVTDRGLIVQLSVSHPAASRVAPYGGTKPLLTPNPMAAGFPT-SADPILIDV 179
Query: 587 ATT 595
+ +
Sbjct: 180 SAS 182
>UniRef50_UPI000050FF64 Cluster: COG2055: Malate/L-lactate
dehydrogenases; n=1; Brevibacterium linens BL2|Rep:
COG2055: Malate/L-lactate dehydrogenases -
Brevibacterium linens BL2
Length = 332
Score = 50.0 bits (114), Expect = 6e-05
Identities = 40/175 (22%), Positives = 72/175 (41%)
Frame = +2
Query: 80 EARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCAK 259
E R ++ G A + A + AD G L Y++ + + + A
Sbjct: 19 ELERLCTSAILDAGGSEKLAASLAAATVAADRRDKIQVGTAHLFDYLDGLEAGRINGAAV 78
Query: 260 PVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALK 439
P + A LVD + + D + A + G+ + + G GY+ ++
Sbjct: 79 PRSVNRLPAAHLVDADGGIVQLAFDEVFDRFAQSATDLGISILNIMNAFPAGELGYYTMR 138
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVA 604
++GLI L+ NS ++ S+ + GTNP++ A P G + D A++A A
Sbjct: 139 LARRGLIALAGGNSPALMSLFGSRDTVTGTNPLSFALPHPQGPRM-FDQASSATA 192
>UniRef50_Q7WEF1 Cluster: Putative malate/L-lactate dehydrogenase;
n=1; Bordetella bronchiseptica|Rep: Putative
malate/L-lactate dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 356
Score = 49.2 bits (112), Expect = 1e-04
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 4/201 (1%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPCA 256
+ A+ F G ++A A A L+ AD +GH SHGL +Y++ +
Sbjct: 13 DSAQHFTARLFERNGLEPAKAAAVARSLVRADMMGHDSHGLALASWYLDALADGQMASQG 72
Query: 257 KPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWAL 436
P ++ + A +G GA + M+ + + + G S H G +
Sbjct: 73 APEVIADRGACFAWNGQRLPGAWLIERAMEAGVERVRTHGSATCTIANSFHAGALAAYLE 132
Query: 437 KAEKQGLIGLSFTNSSP---ILVPTRSKTSALGTNPIALAAPAKNGDNLVVDLATTAVAM 607
+ QGL+ + T S P + P + NP+A P +++D++ +
Sbjct: 133 QLTAQGLLAI-LTCSGPASRAVAPFGGTEALFSPNPLAAGIPTSQAP-MLMDISCSITTT 190
Query: 608 GKV-EIQVHKRGAVASWLGSR 667
+ ++ R A+W +R
Sbjct: 191 NRTRQLARQGRAFPAAWALTR 211
>UniRef50_Q1M3V2 Cluster: Putative malate/lactate dehydrogenase
family protein; n=2; Rhizobium|Rep: Putative
malate/lactate dehydrogenase family protein - Rhizobium
leguminosarum bv. viciae (strain 3841)
Length = 334
Score = 48.4 bits (110), Expect = 2e-04
Identities = 40/178 (22%), Positives = 63/178 (35%), Gaps = 1/178 (0%)
Frame = +2
Query: 74 VEEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATDPC 253
+ E R ++ A G + AKA D + A G G Y+ + +
Sbjct: 10 IGELRHLALEACLACGGSPAMAKALVDATLSAACFGRTELGFPHFVDYLTSLRDGRINGD 69
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
AKP A D + + D + + G+ R S G GY+
Sbjct: 70 AKPRFNHVLPALIQADADGGIAQLGFDLIYDDFTTRVKTFGISVFTQRNSYTAGELGYYV 129
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNG-DNLVVDLATTAVA 604
+ + GLI ++ N ++ TNP+A P LV+D AT+A A
Sbjct: 130 RRLAQDGLISIAAANGPALMAAAEGGERVYCTNPLAFGLPLPEPLPPLVIDQATSATA 187
>UniRef50_Q8GKS5 Cluster: NalP; n=5; Neisseria meningitidis|Rep:
NalP - Neisseria meningitidis
Length = 1083
Score = 37.5 bits (83), Expect = 0.33
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Frame = +2
Query: 401 SNHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALAA---PAKNGDN 571
SNH G+ W L A + + FT ++PI + S ++ + T AL P + DN
Sbjct: 394 SNHCGITAMWCLSAPYEA--SVRFTRTNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDN 451
Query: 572 LVVDLATTAVAMGKVEI 622
L L TTA +G V +
Sbjct: 452 LRTTLLTTAQDIGAVGV 468
>UniRef50_Q9A3U5 Cluster: Peptidase, M20/M25/M40 family; n=27;
Proteobacteria|Rep: Peptidase, M20/M25/M40 family -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 430
Score = 37.1 bits (82), Expect = 0.44
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Frame = +2
Query: 308 DALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSP 487
DA G + N +D A A +G +AA + A+ AE++GL+G + S+P
Sbjct: 209 DAKGDKIYNGAVDNATGIAAMLEMGRLAASGPKPDRSMVFLAVTAEERGLLGSEYYASNP 268
Query: 488 ILVPTRSKTSALGTNPIALAAPAKN---GDNLVVDLATTAVAMGK 613
L P + T+ + PAK+ N +DL +A GK
Sbjct: 269 -LYPLAKTAGVINTDALDPTGPAKDFTISGNAKLDLLDDLIAKGK 312
>UniRef50_Q9XBE9 Cluster: Putative phosphonopyruvate decarboxylase;
n=1; Amycolatopsis orientalis|Rep: Putative
phosphonopyruvate decarboxylase - Amycolatopsis
orientalis
Length = 371
Score = 37.1 bits (82), Expect = 0.44
Identities = 23/59 (38%), Positives = 28/59 (47%)
Frame = +2
Query: 371 AGVGWVAARRSNHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTNPIALA 547
A V W A R+N Y A A AE QG++G + T P LV R + S P A A
Sbjct: 289 ATVDWPALARANGYRDAWLCADGAELQGVLGKALTQPGPCLVAVRIRASETDVPPRASA 347
>UniRef50_UPI0000673706 Cluster: COG2055: Malate/L-lactate
dehydrogenases; n=1; Shigella dysenteriae 1012|Rep:
COG2055: Malate/L-lactate dehydrogenases - Shigella
dysenteriae 1012
Length = 107
Score = 36.7 bits (81), Expect = 0.59
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +2
Query: 77 EEARRFMEDSLTAVGAPVSEAKAQADLLIHADTVGHYSHGLNRLEFYINDILSKATD 247
E + +E+ L G A A++L++AD G +SHG R+E+Y I T+
Sbjct: 6 ETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTN 62
>UniRef50_Q1NGL2 Cluster: Putative uncharacterized protein; n=1;
Sphingomonas sp. SKA58|Rep: Putative uncharacterized
protein - Sphingomonas sp. SKA58
Length = 964
Score = 35.9 bits (79), Expect = 1.0
Identities = 32/127 (25%), Positives = 52/127 (40%)
Frame = -2
Query: 660 PNQLATAPLLCTCISTLPIATAVVAKSTTKLSPFLAGAAKAMGFVPNALVLDLVGTNIGE 481
P ++ AP+ + S P+A A VA +T+ L P + P+A +D NI
Sbjct: 304 PVPVSPAPVADSAPS--PVAAAPVAPATSLLQPAMPSHPSPPQ--PDAAPVDAGAPNIAT 359
Query: 480 EFVNDSPMRPCFSAFNAQYPAIPXXXXXLAATHPTPASCAFLIATSIQKFPTVAPKASQP 301
S P PA+P +A+ H AS + P +AP +++P
Sbjct: 360 TMSPQSAGLPPQPIAAPIDPAVPMADHPVASDHAPVASSTVPVENRAVPAPPMAPPSAEP 419
Query: 300 STRAVAA 280
A++A
Sbjct: 420 QAAAISA 426
>UniRef50_Q019K7 Cluster: Putative phosphate/phosphoenolpyruvate
translocator protein; n=1; Ostreococcus tauri|Rep:
Putative phosphate/phosphoenolpyruvate translocator
protein - Ostreococcus tauri
Length = 352
Score = 35.9 bits (79), Expect = 1.0
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = -2
Query: 678 FRLGLEPNQLATAPLLCTCISTLPIATAVVAKSTTKLSPFLAGAAKAMG 532
F +GL L P L C S +PI V+ S T++S +AG AMG
Sbjct: 152 FSVGLSAAFLGAIPSLALCASLIPIIAGVMIASATEVSFNMAGFLSAMG 200
>UniRef50_A4RXB0 Cluster: DMT family transporter:
glucose-6-phosphate/phosphate; n=5; Viridiplantae|Rep:
DMT family transporter: glucose-6-phosphate/phosphate -
Ostreococcus lucimarinus CCE9901
Length = 327
Score = 35.1 bits (77), Expect = 1.8
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = -2
Query: 678 FRLGLEPNQLATAPLLCTCISTLPIATAVVAKSTTKLSPFLAGAAKAMG 532
F +GL L P L C S +PI V+ S T++S +AG AMG
Sbjct: 131 FSVGLSAIFLGNIPSLAMCASLVPIIAGVMIASATEVSFNMAGFLSAMG 179
>UniRef50_Q92S49 Cluster: Nicotinate phosphoribosyltransferase;
n=57; Bacteria|Rep: Nicotinate phosphoribosyltransferase
- Rhizobium meliloti (Sinorhizobium meliloti)
Length = 434
Score = 34.7 bits (76), Expect = 2.4
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Frame = +2
Query: 398 RSNHYGMAGYWALKAEKQGLIGLSFTNSSPILVPTRSKTSALGTN----PIALAAPAKNG 565
R H + W ++A K+G IG SFT SS +L+ + A+GTN P+ AA +N
Sbjct: 197 RRRHSFLWQRWCVEALKEG-IGSSFTGSSNVLLAMDNDLEAVGTNAHELPMVAAALTRND 255
Query: 566 DNL 574
L
Sbjct: 256 REL 258
>UniRef50_Q3A839 Cluster: Molybdopterin oxidoreductase/precorrin-4
methylase; n=1; Pelobacter carbinolicus DSM 2380|Rep:
Molybdopterin oxidoreductase/precorrin-4 methylase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 607
Score = 33.9 bits (74), Expect = 4.1
Identities = 20/40 (50%), Positives = 22/40 (55%)
Frame = +2
Query: 506 SKTSALGTNPIALAAPAKNGDNLVVDLATTAVAMGKVEIQ 625
S S L NP LAA AKNGD L + T A+ MG E Q
Sbjct: 501 SVPSGLKENPQLLAALAKNGDTLAKNGDTLAIFMGLKEFQ 540
>UniRef50_Q5ADQ7 Cluster: Possible secreted protein; n=1; Candida
albicans|Rep: Possible secreted protein - Candida
albicans (Yeast)
Length = 430
Score = 33.9 bits (74), Expect = 4.1
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Frame = +2
Query: 449 QGLIGLSFTNSSPILVPTRSKTSALGTNPIALAAPAKNGDNLV-VDLATT 595
QGL G+ T + P+R+ T+ +NPIA N +NL D A T
Sbjct: 78 QGLFGVGRTTLGQVTTPSRTSTTTTTSNPIAPTTSIANSNNLFGTDTAPT 127
>UniRef50_A0T6Y3 Cluster: Putative uncharacterized protein; n=1;
Burkholderia ambifaria MC40-6|Rep: Putative
uncharacterized protein - Burkholderia ambifaria MC40-6
Length = 748
Score = 33.5 bits (73), Expect = 5.5
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +1
Query: 253 CKAGDIERVGCDRSGGRLRRFRCYCRKLLYGCRDKEGAGSGSR 381
C+ GD++R +++ RRF + R+LL G RD G G R
Sbjct: 112 CRGGDVDRRHHEQAARTRRRFADHRRRLLRGRRDLRGIRDGHR 154
>UniRef50_Q2HG74 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 705
Score = 33.5 bits (73), Expect = 5.5
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
Frame = +2
Query: 239 ATDPCAKPVILKESAATALVDGCD-----ALGATVGN-----FCMDVAIRKAQEAGVGWV 388
AT+P E+AA A+ DG D LGA +G+ + +A+R+A A
Sbjct: 346 ATNPTVATQTPTEAAAAAVTDGSDPQLNTILGAVLGSIFGAAILLVLAVRRASSAATSNK 405
Query: 389 AARRSNHYGMAGYWALKAEKQGLIGLSFTNSS 484
A R +H + WA EK GL +S+
Sbjct: 406 APRAPSHRWRSS-WARAGEKSAATGLGRKSSN 436
>UniRef50_A7EDA2 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 543
Score = 33.5 bits (73), Expect = 5.5
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +2
Query: 476 NSSPILVPTRSKTSALGTNPIALAAPAKNG 565
N+ +VPTRS TS NP LAAPA+ G
Sbjct: 275 NTQENVVPTRSTTSPTKRNPSKLAAPARGG 304
>UniRef50_Q7NUQ9 Cluster: Putative uncharacterized protein; n=1;
Chromobacterium violaceum|Rep: Putative uncharacterized
protein - Chromobacterium violaceum
Length = 763
Score = 33.1 bits (72), Expect = 7.2
Identities = 22/89 (24%), Positives = 40/89 (44%)
Frame = +2
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
A L+E + AL + LGA + +FC A+ + +AGVG + W
Sbjct: 354 ASSAALRECSPAALRQAAERLGAELDHFC---AVAQQLDAGVGKRQGGAQIEKSIVSSWQ 410
Query: 434 LKAEKQGLIGLSFTNSSPILVPTRSKTSA 520
K + L ++ +++ +L+ RS+ A
Sbjct: 411 GKRREDALANMALAHAA-LLIAARSRGDA 438
>UniRef50_Q9LX31 Cluster: Tetrapyrrole-binding protein, chloroplast
precursor; n=2; Arabidopsis thaliana|Rep:
Tetrapyrrole-binding protein, chloroplast precursor -
Arabidopsis thaliana (Mouse-ear cress)
Length = 265
Score = 33.1 bits (72), Expect = 7.2
Identities = 20/51 (39%), Positives = 24/51 (47%)
Frame = -2
Query: 663 EPNQLATAPLLCTCISTLPIATAVVAKSTTKLSPFLAGAAKAMGFVPNALV 511
+P AT L+C+ ST TAV A STT S A A + N LV
Sbjct: 39 QPTSAATFSLICSASSTSSSTTAVSAVSTTNASATTAETATIFDVLENHLV 89
>UniRef50_UPI00006DB94B Cluster: hypothetical protein
BdolA_01003443; n=1; Burkholderia dolosa AUO158|Rep:
hypothetical protein BdolA_01003443 - Burkholderia
dolosa AUO158
Length = 69
Score = 32.7 bits (71), Expect = 9.5
Identities = 17/30 (56%), Positives = 20/30 (66%)
Frame = -2
Query: 609 PIATAVVAKSTTKLSPFLAGAAKAMGFVPN 520
P A A+VAKS T +P G A A+GFVPN
Sbjct: 3 PRAIALVAKSNTNGTPPGRGHANAIGFVPN 32
>UniRef50_Q9K8R2 Cluster: Glutamate-1-semialdehyde 2,1-aminomutase;
n=1; Bacillus halodurans|Rep: Glutamate-1-semialdehyde
2,1-aminomutase - Bacillus halodurans
Length = 461
Score = 32.7 bits (71), Expect = 9.5
Identities = 20/70 (28%), Positives = 33/70 (47%)
Frame = +2
Query: 179 GHYSHGLNRLEFYINDILSKATDPCAKPVILKESAATALVDGCDALGATVGNFCMDVAIR 358
GHY G N + + ++ LS+A P P+ +KES + DG + L N +
Sbjct: 155 GHYHGGYNDVLYSVSPTLSEA-GPADAPIPVKESKGMHVTDGEEPLILPFNNLTACERLL 213
Query: 359 KAQEAGVGWV 388
+AQ+ + V
Sbjct: 214 RAQQDSIAAV 223
>UniRef50_Q02BJ5 Cluster: Putative uncharacterized protein
precursor; n=1; Solibacter usitatus Ellin6076|Rep:
Putative uncharacterized protein precursor - Solibacter
usitatus (strain Ellin6076)
Length = 767
Score = 32.7 bits (71), Expect = 9.5
Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 AKPVILKESAATALVDGCDALGATVGNFCMDVAIRKAQEAGVGWVAARRSNHYGMAGYWA 433
AKP ++ A AL G L + + ++ ++ G G + A NH M WA
Sbjct: 209 AKPRVIAMCAGGALY-GIPYLAFYILPYLHEIRTAISENQGAGGIGASIRNHVAMYRSWA 267
Query: 434 LKAEKQGLIGLSFTNSSPI-LVPTRSKTSALGTNPIALAA 550
++ LI + +P+ ++ T + T IALAA
Sbjct: 268 HAMDRPVLIRQAMAIGAPLWVISTTLLLAVRSTRGIALAA 307
>UniRef50_A5P3G4 Cluster: Putative uncharacterized protein
precursor; n=1; Methylobacterium sp. 4-46|Rep: Putative
uncharacterized protein precursor - Methylobacterium sp.
4-46
Length = 172
Score = 32.7 bits (71), Expect = 9.5
Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +2
Query: 440 AEKQGLIGLSFTNSSPILVPTRSKTS-ALGTNPIALAAPAKNGDNLVVDLATTAVAMGKV 616
A+ ++GL FT + + T + A GTN +A AAP+K L VDL + +A G
Sbjct: 69 AQYAPVLGLIFTQAR---IETMVRNGIAYGTNAVAGAAPSK---PLTVDLGSQVIASGVR 122
Query: 617 EIQVHKRGAV 646
+Q H A+
Sbjct: 123 YLQAHAPAAI 132
>UniRef50_Q67W22 Cluster: Putative uncharacterized protein
OSJNBa0040M10.6; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OSJNBa0040M10.6 - Oryza sativa subsp. japonica (Rice)
Length = 155
Score = 32.7 bits (71), Expect = 9.5
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Frame = -2
Query: 483 EEFVNDSPMRPCFSAFNAQYPAIPXXXXXLAAT-HPTPASCAFLIATSIQKFPTVAPKAS 307
E F P R CF+AFN P + A+T T SCA + + Q P A S
Sbjct: 59 ENFQTRDPSRHCFAAFNRSSPVLGTMPGDSASTLSTTVPSCA---SATAQSSPCAA--KS 113
Query: 306 QPSTRAV 286
PST AV
Sbjct: 114 PPSTFAV 120
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 742,614,474
Number of Sequences: 1657284
Number of extensions: 14805027
Number of successful extensions: 45622
Number of sequences better than 10.0: 130
Number of HSP's better than 10.0 without gapping: 43602
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45543
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59265488880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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