Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30165
(660 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 187 4e-47
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 187 4e-47
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 187 4e-47
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 187 4e-47
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 187 4e-47
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 187 4e-47
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 187 4e-47
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 187 4e-47
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 187 4e-47
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 187 4e-47
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 187 4e-47
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 187 4e-47
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 187 4e-47
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 182 8e-46
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 177 2e-44
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 176 5e-44
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 173 4e-43
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 173 4e-43
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 173 4e-43
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 173 4e-43
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 173 4e-43
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 173 4e-43
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 173 4e-43
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 172 8e-43
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 93 1e-18
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 77 7e-14
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 73 7e-13
BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein. 33 0.90
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 33 0.90
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 33 0.90
AK130326-1|BAC85327.1| 508|Homo sapiens protein ( Homo sapiens ... 31 2.8
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 25 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 81
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 82 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 141
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 142 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 194
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 187 bits (455), Expect = 4e-47
Identities = 86/173 (49%), Positives = 120/173 (69%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 499
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 500 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 170
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 182 bits (444), Expect = 8e-46
Identities = 80/138 (57%), Positives = 103/138 (74%)
Frame = +2
Query: 245 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 424
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 425 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 604
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 605 MHLYGRNFYGGNGIVGAQ 658
MH+Y +NFYGGNGIVGAQ
Sbjct: 191 MHMYAKNFYGGNGIVGAQ 208
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 177 bits (432), Expect = 2e-44
Identities = 86/180 (47%), Positives = 120/180 (66%), Gaps = 7/180 (3%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQ-------EAVAVGMRAAMRD 478
ED LK Y + +RR+E + LYK+KIIRGFCHL GQ EA VG+ A +
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINP 117
Query: 479 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 TDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 177
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 176 bits (429), Expect = 5e-44
Identities = 77/135 (57%), Positives = 100/135 (74%)
Frame = +2
Query: 245 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 424
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 425 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 604
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 605 MHLYGRNFYGGNGIV 649
MH+Y +NFYGGNGIV
Sbjct: 191 MHMYAKNFYGGNGIV 205
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 43 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 102
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 103 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 162
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 163 AKGKGGSMHMYTKNFYGGNGIVGAQ 187
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 173 bits (422), Expect = 4e-43
Identities = 78/145 (53%), Positives = 102/145 (70%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 172 bits (419), Expect = 8e-43
Identities = 78/145 (53%), Positives = 101/145 (69%)
Frame = +2
Query: 224 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 403
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 404 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 583
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTGRRGGC 143
Query: 584 SRGKGGSMHLYGRNFYGGNGIVGAQ 658
++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQ 168
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 92.7 bits (220), Expect = 1e-18
Identities = 46/110 (41%), Positives = 67/110 (60%)
Frame = +2
Query: 140 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 319
M K++ + + L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSPVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 320 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 469
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLERA 107
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 76.6 bits (180), Expect = 7e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = +2
Query: 245 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 424
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 61 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 120
Query: 425 L 427
L
Sbjct: 121 L 121
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 73.3 bits (172), Expect = 7e-13
Identities = 30/41 (73%), Positives = 37/41 (90%)
Frame = +2
Query: 536 SVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 658
SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 1 SVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 41
>BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein.
Length = 1481
Score = 33.1 bits (72), Expect = 0.90
Identities = 19/40 (47%), Positives = 21/40 (52%)
Frame = -1
Query: 648 TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 529
T PLPP P +PPLP QP V + ST STL P
Sbjct: 548 TPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-STLPP 586
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 33.1 bits (72), Expect = 0.90
Identities = 19/40 (47%), Positives = 21/40 (52%)
Frame = -1
Query: 648 TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 529
T PLPP P +PPLP QP V + ST STL P
Sbjct: 548 TPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-STLPP 586
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 33.1 bits (72), Expect = 0.90
Identities = 19/40 (47%), Positives = 21/40 (52%)
Frame = -1
Query: 648 TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 529
T PLPP P +PPLP QP V + ST STL P
Sbjct: 602 TPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-STLPP 640
>AK130326-1|BAC85327.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ26816 fis, clone PRS06437. ).
Length = 508
Score = 31.5 bits (68), Expect = 2.8
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = -1
Query: 636 PP*KLRPYKCMEP-PLPREQPVLRPVSSESTPSTLTPMR*VHP*QRYAVITESASRIAAL 460
PP KL+P +P P + QP L P ++ P T TP HP Q + + E S + AL
Sbjct: 402 PPPKLQPQPQPQPQPQSQPQPQLPP-QPQTQPQTPTPAP-QHPQQTWPPVNEGESAMRAL 459
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,645,324
Number of Sequences: 237096
Number of extensions: 1901001
Number of successful extensions: 6076
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 5593
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6053
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7422585720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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